-
1
-
-
70049112901
-
Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
-
19713419 10.1093/eurheartj/ehp297
-
Galie N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, Beghetti M, Corris P, Gaine S, Gibbs JS et al (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 30:2493-2537
-
(2009)
Eur Heart J
, vol.30
, pp. 2493-2537
-
-
Galie, N.1
Hoeper, M.M.2
Humbert, M.3
Torbicki, A.4
Vachiery, J.L.5
Barbera, J.A.6
Beghetti, M.7
Corris, P.8
Gaine, S.9
Gibbs, J.S.10
-
2
-
-
67649632034
-
Diagnosis and assessment of pulmonary arterial hypertension
-
19555859 10.1016/j.jacc.2009.04.011
-
Badesch DB, Champion HC, Sanchez MA, Hoeper MM, Loyd JE, Manes A, McGoon M, Naeije R, Olschewski H, Oudiz RJ et al (2009) Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol 54:S55-S66
-
(2009)
J Am Coll Cardiol
, vol.54
-
-
Badesch, D.B.1
Champion, H.C.2
Sanchez, M.A.3
Hoeper, M.M.4
Loyd, J.E.5
Manes, A.6
McGoon, M.7
Naeije, R.8
Olschewski, H.9
Oudiz, R.J.10
-
3
-
-
0033795729
-
Hypoxia-induced pulmonary vascular remodeling: A model for what human disease?
-
10995781 1:CAS:528:DC%2BD3cXms1CgsLY%3D 10.1172/JCI11144
-
Voelkel NF, Tuder RM (2000) Hypoxia-induced pulmonary vascular remodeling: a model for what human disease? J Clin Invest 106:733-738
-
(2000)
J Clin Invest
, vol.106
, pp. 733-738
-
-
Voelkel, N.F.1
Tuder, R.M.2
-
4
-
-
71949129187
-
Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
-
19748998 1:CAS:528:DC%2BD1MXhsFOgtr%2FO 10.1152/ajplung.00217.2009
-
Stenmark KR, Meyrick B, Galie N, Mooi WJ, McMurtry IF (2009) Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol 297:L1013-L1032
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Stenmark, K.R.1
Meyrick, B.2
Galie, N.3
Mooi, W.J.4
McMurtry, I.F.5
-
5
-
-
68049102899
-
Pathology of pulmonary arterial hypertension
-
19634077 10.1055/s-0029-1233307
-
Tuder RM (2009) Pathology of pulmonary arterial hypertension. Semin Respir Crit Care Med 30:376-385
-
(2009)
Semin Respir Crit Care Med
, vol.30
, pp. 376-385
-
-
Tuder, R.M.1
-
6
-
-
77949474595
-
Emerging therapies for the treatment of pulmonary hypertension
-
20216170 10.1097/PCC.0b013e3181c76db3
-
Stenmark KR, Rabinovitch M (2010) Emerging therapies for the treatment of pulmonary hypertension. Pediatr Crit Care Med 11:S85-S90
-
(2010)
Pediatr Crit Care Med
, vol.11
-
-
Stenmark, K.R.1
Rabinovitch, M.2
-
7
-
-
37549020328
-
Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension
-
17989161 10.1378/chest.07-1246
-
Gan CT-J, Lankhaar J-W, Westerhof N, Marcus JT, Becker A, Twisk JWR, Boonstra A, Postmus PE, Vonk-Noordegraaf A (2007) Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension. Chest 132(6):1906-1912
-
(2007)
Chest
, vol.132
, Issue.6
, pp. 1906-1912
-
-
Gan, C.-J.1
Lankhaar, J.-W.2
Westerhof, N.3
Marcus, J.T.4
Becker, A.5
Twisk, J.W.R.6
Boonstra, A.7
Postmus, P.E.8
Vonk-Noordegraaf, A.9
-
8
-
-
32644435423
-
Relationship of pulmonary arterial capacitance and mortality in idiopathic pulmonary arterial hypertension
-
16487848 10.1016/j.jacc.2005.09.054
-
Mahapatra S, Nishimura RA, Sorajja P, Cha S, McGoon MD (2006) Relationship of pulmonary arterial capacitance and mortality in idiopathic pulmonary arterial hypertension. J Am Coll Cardiol 47:799-803
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 799-803
-
-
Mahapatra, S.1
Nishimura, R.A.2
Sorajja, P.3
Cha, S.4
McGoon, M.D.5
-
9
-
-
79251509290
-
Effects of acute Rho kinase inhibition on chronic hypoxia-induced changes in proximal and distal pulmonary arterial structure and function
-
21088209 10.1152/japplphysiol.00533.2010
-
Vanderpool RR, Kim AR, Molthen R, Chesler NC (2011) Effects of acute Rho kinase inhibition on chronic hypoxia-induced changes in proximal and distal pulmonary arterial structure and function. J Appl Physiol 110:188-198
-
(2011)
J Appl Physiol
, vol.110
, pp. 188-198
-
-
Vanderpool, R.R.1
Kim, A.R.2
Molthen, R.3
Chesler, N.C.4
-
10
-
-
22744455284
-
Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation
-
15961717 1:CAS:528:DC%2BD2MXmtFSlt7g%3D 10.1161/01.RES.0000174287.17953. 83
-
Hyvelin J-M, Howell K, Nichol A, Costello CM, Preston RJ, McLoughlin P (2005) Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation. Circ Res 97:185-191
-
(2005)
Circ Res
, vol.97
, pp. 185-191
-
-
Hyvelin, J.-M.1
Howell, K.2
Nichol, A.3
Costello, C.M.4
Preston, R.J.5
McLoughlin, P.6
-
11
-
-
22744457972
-
Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: A time for reappraisal?
-
16037575 1:CAS:528:DC%2BD2MXos1Gms7Y%3D 10.1161/01.RES.00000175934.68087. 29
-
Stenmark KR, McMurtry IF (2005) Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal? Circ Res 97:95-98
-
(2005)
Circ Res
, vol.97
, pp. 95-98
-
-
Stenmark, K.R.1
McMurtry, I.F.2
-
12
-
-
77951239891
-
Rho kinase-mediated vasoconstriction in pulmonary hypertension
-
20204738 1:CAS:528:DC%2BC3cXhsFyjtrrK 10.1007/978-1-60761-500-2-19
-
McMurtry IV, Abe K, Ota H, Fagan KA, Oka M (2010) Rho kinase-mediated vasoconstriction in pulmonary hypertension. Adv Exp Med Biol 661:299-308
-
(2010)
Adv Exp Med Biol
, vol.661
, pp. 299-308
-
-
McMurtry, I.V.1
Abe, K.2
Ota, H.3
Fagan, K.A.4
Oka, M.5
-
13
-
-
0000399371
-
The heart and pulmonary circulation in children at high altitudes: Physiological, anatomical, and clinical observations
-
14212475 1:STN:280:DyaF2M%2Fhs1yltQ%3D%3D
-
Penaloza D, Arias-Stella J, Sime F, Recavarren S, Marticorena E (1964) The heart and pulmonary circulation in children at high altitudes: physiological, anatomical, and clinical observations. Pediatrics 34:568-582
-
(1964)
Pediatrics
, vol.34
, pp. 568-582
-
-
Penaloza, D.1
Arias-Stella, J.2
Sime, F.3
Recavarren, S.4
Marticorena, E.5
-
14
-
-
0000307930
-
Pulmonary circulation at sea level and at high altitudes
-
13376451
-
Rotta A, Canepa A, Hurtado A, Velasquez T, Chavez R (1956) Pulmonary circulation at sea level and at high altitudes. J Appl Physiol 9:328-336
-
(1956)
J Appl Physiol
, vol.9
, pp. 328-336
-
-
Rotta, A.1
Canepa, A.2
Hurtado, A.3
Velasquez, T.4
Chavez, R.5
-
15
-
-
11744278432
-
Electrocardiographic observation of 493 residents living at high altitude (10,150 feet)
-
5834470 1:STN:280:DyaF28%2Fhs12mtA%3D%3D 10.1016/0002-9149(65)90025-1
-
Pryor R, Weaver WF, Blount SG (1965) Electrocardiographic observation of 493 residents living at high altitude (10,150 feet). Am J Cardiol 16:494-499
-
(1965)
Am J Cardiol
, vol.16
, pp. 494-499
-
-
Pryor, R.1
Weaver, W.F.2
Blount, S.G.3
-
16
-
-
0001644427
-
Hypoxemia and pulmonary hypertension. A study of the pulmonary vasculature
-
13727385 1:STN:280:DyaF3c%2FkslSjtw%3D%3D
-
Naeye RL (1961) Hypoxemia and pulmonary hypertension. A study of the pulmonary vasculature. Arch Pathol 71:447-452
-
(1961)
Arch Pathol
, vol.71
, pp. 447-452
-
-
Naeye, R.L.1
-
17
-
-
0007153930
-
Children at high altitude: Pulmonary and renal abnormalities
-
14252154 1:STN:280:DyaF2M%2Fls1Kmsw%3D%3D 10.1161/01.RES.16.1.33
-
Naeye RL (1965) Children at high altitude: pulmonary and renal abnormalities. Circ Res 16:33-38
-
(1965)
Circ Res
, vol.16
, pp. 33-38
-
-
Naeye, R.L.1
-
18
-
-
0001507064
-
The terminal portion of the pulmonary arterial tree in people native to high altitudes
-
14079195 1:STN:280:DyaF2c%2Fjs1ygtA%3D%3D 10.1161/01.CIR.28.5.915
-
Arias-Stella J, Saldana M (1963) The terminal portion of the pulmonary arterial tree in people native to high altitudes. Circulation 28:915-925
-
(1963)
Circulation
, vol.28
, pp. 915-925
-
-
Arias-Stella, J.1
Saldana, M.2
-
19
-
-
0019479960
-
Small pulmonary arteries in some natives of la Paz, Bolivia
-
7314035 1:STN:280:DyaL38%2FosFejsg%3D%3D 10.1136/thx.36.8.599
-
Heath D, Smith P, Rios Dalenz J, Williams D, Harris P (1981) Small pulmonary arteries in some natives of La Paz, Bolivia. Thorax 36:599-604
-
(1981)
Thorax
, vol.36
, pp. 599-604
-
-
Heath, D.1
Smith, P.2
Rios Dalenz, J.3
Williams, D.4
Harris, P.5
-
20
-
-
0027477952
-
Minimal hypoxic pulmonary hypertension in normal Tibetans at 3,658 m
-
8444708 1:STN:280:DyaK3s7os1Gqtg%3D%3D
-
Groves BM, Droma T, Sutton JR, McCullough RG, McCullough RE, Zhuang J, Rapmund G, Sun S, Janes C, Moore LG (1993) Minimal hypoxic pulmonary hypertension in normal Tibetans at 3,658 m. J Appl Physiol 74:312-318
-
(1993)
J Appl Physiol
, vol.74
, pp. 312-318
-
-
Groves, B.M.1
Droma, T.2
Sutton, J.R.3
McCullough, R.G.4
McCullough, R.E.5
Zhuang, J.6
Rapmund, G.7
Sun, S.8
Janes, C.9
Moore, L.G.10
-
21
-
-
0026785650
-
Lack of smooth muscle in the small pulmonary arteries of the native Ladakhi. Is the Himalayan highlander adapted?
-
1586066 1:STN:280:DyaK383msVGqtA%3D%3D 10.1164/ajrccm/145.5.1201
-
Gupta ML, Rao KS, Anand IS, Banerjee AK, Boparai MS (1992) Lack of smooth muscle in the small pulmonary arteries of the native Ladakhi. Is the Himalayan highlander adapted? Am Rev Respir Dis 145:1201-1204
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 1201-1204
-
-
Gupta, M.L.1
Rao, K.S.2
Anand, I.S.3
Banerjee, A.K.4
Boparai, M.S.5
-
22
-
-
0023928253
-
A pathophysiological study of 10 cases of hypoxic cor pulmonale
-
3174923 1:STN:280:DyaL1M%2FhslOnsQ%3D%3D
-
Wilkinson M, Langhorne CA, Heath D, Barer GR, Howard P (1988) A pathophysiological study of 10 cases of hypoxic cor pulmonale. Q J Med 66:65-85
-
(1988)
Q J Med
, vol.66
, pp. 65-85
-
-
Wilkinson, M.1
Langhorne, C.A.2
Heath, D.3
Barer, G.R.4
Howard, P.5
-
23
-
-
0028014624
-
Pulmonary vascular abnormalities and ventilation-perfusion relationships in mild chronic obstructive pulmonary disease
-
8306040
-
Barberà JA, Riverola A, Roca J, Ramirez J, Wagner PD, Ros D, Wiggs BR, Rodriguez-Roisin R (1994) Pulmonary vascular abnormalities and ventilation-perfusion relationships in mild chronic obstructive pulmonary disease. Am J Respir Crit Care Med 149:423-429
-
(1994)
Am J Respir Crit Care Med
, vol.149
, pp. 423-429
-
-
Barberà, J.A.1
Riverola, A.2
Roca, J.3
Ramirez, J.4
Wagner, P.D.5
Ros, D.6
Wiggs, B.R.7
Rodriguez-Roisin, R.8
-
24
-
-
0026573643
-
Analysis of the structure of the muscular pulmonary arteries in patients with pulmonary hypertension and COPD: National Institutes of Health nocturnal oxygen therapy trial
-
1501507 1:STN:280:DyaK38zmsFCisw%3D%3D 10.1007/BF00175982
-
Wright JL, Petty T, Thurlbeck WM (1992) Analysis of the structure of the muscular pulmonary arteries in patients with pulmonary hypertension and COPD: National Institutes of Health nocturnal oxygen therapy trial. Lung 170:109-124
-
(1992)
Lung
, vol.170
, pp. 109-124
-
-
Wright, J.L.1
Petty, T.2
Thurlbeck, W.M.3
-
25
-
-
0036212004
-
Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD
-
11998991 1:STN:280:DC%2BD383lvFGmug%3D%3D 10.1183/09031936.02.00245902
-
Santos S, Peinado VI, Ramírez J, Melgosa T, Roca J, Rodriguez-Roisin R, Barberà JA (2002) Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD. Eur Respir J 19:632-638
-
(2002)
Eur Respir J
, vol.19
, pp. 632-638
-
-
Santos, S.1
Peinado, V.I.2
Ramírez, J.3
Melgosa, T.4
Roca, J.5
Rodriguez-Roisin, R.6
Barberà, J.A.7
-
28
-
-
14144255938
-
Comparative physiology of hypoxic pulmonary hypertension: Historical clues from brisket disease
-
15703167 10.1152/japplphysiol.01017.2004
-
Rhodes J (2005) Comparative physiology of hypoxic pulmonary hypertension: historical clues from brisket disease. J Appl Physiol 98:1092-1100
-
(2005)
J Appl Physiol
, vol.98
, pp. 1092-1100
-
-
Rhodes, J.1
-
29
-
-
0023203985
-
Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m
-
3558241 1:STN:280:DyaL2s7msFKhtw%3D%3D
-
Stenmark KR, Fasules J, Hyde DM, Voelkel NF, Henson J, Tucker A, Wilson H, Reeves JT (1987) Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m. J Appl Physiol 62:821-830
-
(1987)
J Appl Physiol
, vol.62
, pp. 821-830
-
-
Stenmark, K.R.1
Fasules, J.2
Hyde, D.M.3
Voelkel, N.F.4
Henson, J.5
Tucker, A.6
Wilson, H.7
Reeves, J.T.8
-
30
-
-
0018487516
-
Rat pulmonary circulation after chronic hypoxia: Hemodynamic and structural features
-
443445 1:CAS:528:DyaE1MXktlKktrg%3D
-
Rabinovitch M, Gamble WJ, Nadas AS, Miettinen OS, Reid L (1979) Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features. Am J Physiol 236:H818-H827
-
(1979)
Am J Physiol
, vol.236
-
-
Rabinovitch, M.1
Gamble, W.J.2
Nadas, A.S.3
Miettinen, O.S.4
Reid, L.5
-
31
-
-
35349028821
-
Point:counterpoint: Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature
-
17363624 10.1152/japplphysiol.00274.2007
-
Rabinovitch M, Chesler N, Molthen RC (2007) Point:counterpoint: chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature. J Appl Physiol 103:1449-1451
-
(2007)
J Appl Physiol
, vol.103
, pp. 1449-1451
-
-
Rabinovitch, M.1
Chesler, N.2
Molthen, R.C.3
-
32
-
-
0017099110
-
New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension
-
136978 1:STN:280:DyaE2s%2FmsFCruw%3D%3D
-
Hislop A, Reid L (1976) New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. Br J Exp Pathol 57:542-554
-
(1976)
Br J Exp Pathol
, vol.57
, pp. 542-554
-
-
Hislop, A.1
Reid, L.2
-
33
-
-
35348961449
-
Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature
-
17916681 10.1152/japplphysiol.00739.2007
-
Berg JT (2007) Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature. J Appl Physiol 103:1455
-
(2007)
J Appl Physiol
, vol.103
, pp. 1455
-
-
Berg, J.T.1
-
34
-
-
38449097957
-
Counterpoint: Chronic hypoxia-induced pulmonary hypertension does not lead to loss of pulmonary vasculature
-
17916678 1:STN:280:DC%2BD2srpsV2qtA%3D%3D 10.1152/japplphysiol.00274. 2007a discussion 1453-1454
-
Mcloughlin P, Mcmurtry I (2007) Counterpoint: chronic hypoxia-induced pulmonary hypertension does not lead to loss of pulmonary vasculature. J Appl Physiol 103:1451-1453, discussion 1453-1454
-
(2007)
J Appl Physiol
, vol.103
, pp. 1451-1453
-
-
McLoughlin, P.1
McMurtry, I.2
-
35
-
-
0037440743
-
Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation
-
12562951 1:CAS:528:DC%2BD3sXivFSkt7s%3D 10.1113/jphysiol.2002.030676
-
Howell K, Preston RJ, McLoughlin P (2003) Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation. J Physiol 547:133-145
-
(2003)
J Physiol
, vol.547
, pp. 133-145
-
-
Howell, K.1
Preston, R.J.2
McLoughlin, P.3
-
37
-
-
34248187453
-
Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
-
17319968 10.1186/1465-9921-8-15 1:CAS:528:DC%2BD2sXktVaktL8%3D
-
Paddenberg R, Stieger P, Von Lilien A-L, Faulhammer P, Goldenberg A, Tillmanns HH, Kummer W, Braun-Dullaeus RC (2007) Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice. Respir Res 8:15
-
(2007)
Respir Res
, vol.8
, pp. 15
-
-
Paddenberg, R.1
Stieger, P.2
Von Lilien, A.-L.3
Faulhammer, P.4
Goldenberg, A.5
Tillmanns, H.H.6
Kummer, W.7
Braun-Dullaeus, R.C.8
-
38
-
-
33749345684
-
Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
-
17008597 1:CAS:528:DC%2BD28XpvFertro%3D 10.1161/01.RES.0000243584.45145. 3f
-
Stenmark KR, Fagan KA, Frid MG (2006) Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 99:675-691
-
(2006)
Circ Res
, vol.99
, pp. 675-691
-
-
Stenmark, K.R.1
Fagan, K.A.2
Frid, M.G.3
-
39
-
-
0015805208
-
Fine structural alterations of bovine peripheral pulmonary arteries in hypoxia-induced hypertension
-
4357176 1:STN:280:DyaE2c%2FksFegtA%3D%3D
-
Jaenke RS, Alexander AF (1973) Fine structural alterations of bovine peripheral pulmonary arteries in hypoxia-induced hypertension. Am J Pathol 73:377-398
-
(1973)
Am J Pathol
, vol.73
, pp. 377-398
-
-
Jaenke, R.S.1
Alexander, A.F.2
-
40
-
-
0034943184
-
Mild hypoxia causes severe pulmonary hypertension in fawn-hooded but not in Tester Moriyama rats
-
11445200 1:STN:280:DC%2BD3MzptFCgtg%3D%3D 10.1016/S0034-5687(01)00217-1
-
Nagaoka T, Muramatsu M, Sato K, McMurtry I, Oka M, Fukuchi Y (2001) Mild hypoxia causes severe pulmonary hypertension in fawn-hooded but not in Tester Moriyama rats. Respir Physiol 127:53-60
-
(2001)
Respir Physiol
, vol.127
, pp. 53-60
-
-
Nagaoka, T.1
Muramatsu, M.2
Sato, K.3
McMurtry, I.4
Oka, M.5
Fukuchi, Y.6
-
41
-
-
0026524283
-
Factors influencing the idiopathic development of pulmonary hypertension in the fawn hooded rat
-
1554204 1:STN:280:DyaK383gs1Onsw%3D%3D
-
Sato K, Webb S, Tucker A, Rabinovitch M, O'Brien RF, McMurtry IF, Stelzner TJ (1992) Factors influencing the idiopathic development of pulmonary hypertension in the fawn hooded rat. Am Rev Respir Dis 145:793-797
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 793-797
-
-
Sato, K.1
Webb, S.2
Tucker, A.3
Rabinovitch, M.4
O'Brien, R.F.5
McMurtry, I.F.6
Stelzner, T.J.7
-
42
-
-
0035130107
-
Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
-
11156958 1:CAS:528:DC%2BD3MXhsFemsrw%3D 10.1096/fj.00-0343com
-
Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM (2001) Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J 15:427-438
-
(2001)
FASEB J
, vol.15
, pp. 427-438
-
-
Taraseviciene-Stewart, L.1
Kasahara, Y.2
Alger, L.3
Hirth, P.4
Mc Mahon, G.5
Waltenberger, J.6
Voelkel, N.F.7
Tuder, R.M.8
-
43
-
-
77954243018
-
Formation of plexiform lesions in experimental severe pulmonary arterial hypertension
-
20547927 10.1161/CIRCULATIONAHA.109.927681
-
Abe K, Toba M, Alzoubi A, Ito M, Fagan KA, Cool CD, Voelkel NF, McMurtry IF, Oka M (2010) Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation 121:2747-2754
-
(2010)
Circulation
, vol.121
, pp. 2747-2754
-
-
Abe, K.1
Toba, M.2
Alzoubi, A.3
Ito, M.4
Fagan, K.A.5
Cool, C.D.6
Voelkel, N.F.7
McMurtry, I.F.8
Oka, M.9
-
44
-
-
81455150134
-
A novel murine model of severe pulmonary arterial hypertension
-
10.1164/rccm.201103-0412OC 1:CAS:528:DC%2BC3MXhs1ejsLbI
-
Ciuclan L, Bonneau O, Hussey M, Duggan N, Holmes AM, Good R, Stringer R, Jones P, Morrell NW, Jarai G et al (2012) A novel murine model of severe pulmonary arterial hypertension. Am J Respir Crit Care Med 184:1171-1182
-
(2012)
Am J Respir Crit Care Med
, vol.184
, pp. 1171-1182
-
-
Ciuclan, L.1
Bonneau, O.2
Hussey, M.3
Duggan, N.4
Holmes, A.M.5
Good, R.6
Stringer, R.7
Jones, P.8
Morrell, N.W.9
Jarai, G.10
-
45
-
-
0014061764
-
Pulmonary hypertension produced in rats by ingestion of Crotalaria spectabilis seeds
-
6033385 1:STN:280:DyaF2s3gvVeltg%3D%3D 10.1136/thx.22.2.176
-
Kay JM, Harris P, Heath D (1967) Pulmonary hypertension produced in rats by ingestion of Crotalaria spectabilis seeds. Thorax 22:176-179
-
(1967)
Thorax
, vol.22
, pp. 176-179
-
-
Kay, J.M.1
Harris, P.2
Heath, D.3
-
46
-
-
84861165497
-
A brief overview of mouse models of pulmonary arterial hypertension: Problems and prospects
-
22307907 1:CAS:528:DC%2BC38XotVygu7k%3D 10.1152/ajplung.00362.2011
-
Gomez-Arroyo J, Saleem SJ, Mizuno S, Syed AA, Bogaard HJ, Abbate A, Taraseviciene-Stewart L, Sung Y, Kraskauskas D, Farkas D et al (2012) A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. Am J Physiol Lung Cell Mol Physiol 302:L977-L991
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
-
-
Gomez-Arroyo, J.1
Saleem, S.J.2
Mizuno, S.3
Syed, A.A.4
Bogaard, H.J.5
Abbate, A.6
Taraseviciene-Stewart, L.7
Sung, Y.8
Kraskauskas, D.9
Farkas, D.10
-
47
-
-
0019082316
-
Development of Crotalaria pulmonary hypertension: Hemodynamic and structural study
-
6449154 1:STN:280:DyaL3M%2FlvFymuw%3D%3D
-
Meyrick B, Gamble W, Reid L (1980) Development of Crotalaria pulmonary hypertension: hemodynamic and structural study. Am J Physiol 239:H692-H702
-
(1980)
Am J Physiol
, vol.239
-
-
Meyrick, B.1
Gamble, W.2
Reid, L.3
-
48
-
-
0030036720
-
The role of vascular injury and hemodynamics in rat pulmonary artery remodeling
-
8755654 1:CAS:528:DyaK28XksFCltrw%3D 10.1172/JCI118809
-
Tanaka Y, Schuster DP, Davis EC, Patterson GA, Botney MD (1996) The role of vascular injury and hemodynamics in rat pulmonary artery remodeling. J Clin Invest 98:434-442
-
(1996)
J Clin Invest
, vol.98
, pp. 434-442
-
-
Tanaka, Y.1
Schuster, D.P.2
Davis, E.C.3
Patterson, G.A.4
Botney, M.D.5
-
49
-
-
0030828893
-
Pulmonary hemodynamics modify the rat pulmonary artery response to injury. A neointimal model of pulmonary hypertension
-
9327735 1:STN:280:DyaK2svmvVKksg%3D%3D
-
Okada K, Tanaka Y, Bernstein M, Zhang W, Patterson GA, Botney MD (1997) Pulmonary hemodynamics modify the rat pulmonary artery response to injury. A neointimal model of pulmonary hypertension. Am J Pathol 151:1019-1025
-
(1997)
Am J Pathol
, vol.151
, pp. 1019-1025
-
-
Okada, K.1
Tanaka, Y.2
Bernstein, M.3
Zhang, W.4
Patterson, G.A.5
Botney, M.D.6
-
50
-
-
77951227152
-
The serotonin hypothesis of pulmonary hypertension revisited
-
20204739 1:CAS:528:DC%2BC3cXhsFyjtrrE 10.1007/978-1-60761-500-2-20
-
Maclean MR, Dempsie Y (2010) The serotonin hypothesis of pulmonary hypertension revisited. Adv Exp Med Biol 661:309-322
-
(2010)
Adv Exp Med Biol
, vol.661
, pp. 309-322
-
-
Maclean, M.R.1
Dempsie, Y.2
-
51
-
-
0013023197
-
Contractile responses to human urotensin-II in rat and human pulmonary arteries: Effect of endothelial factors and chronic hypoxia in the rat
-
10807654 1:CAS:528:DC%2BD3cXjsl2mtLg%3D 10.1038/sj.bjp.0703314
-
MacLean MR, Alexander D, Stirrat A, Gallagher M, Douglas SA, Ohlstein EH, Morecroft I, Polland K (2000) Contractile responses to human urotensin-II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat. Br J Pharmacol 130:201-204
-
(2000)
Br J Pharmacol
, vol.130
, pp. 201-204
-
-
Maclean, M.R.1
Alexander, D.2
Stirrat, A.3
Gallagher, M.4
Douglas, S.A.5
Ohlstein, E.H.6
Morecroft, I.7
Polland, K.8
-
52
-
-
0032971293
-
Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin
-
10024307 1:CAS:528:DyaK1MXhsVaksb0%3D 10.1161/01.RES.84.3.329
-
Eddahibi S, Fabre V, Boni C, Martres MP, Raffestin B, Hamon M, Adnot S (1999) Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin. Circ Res 84:329-336
-
(1999)
Circ Res
, vol.84
, pp. 329-336
-
-
Eddahibi, S.1
Fabre, V.2
Boni, C.3
Martres, M.P.4
Raffestin, B.5
Hamon, M.6
Adnot, S.7
-
53
-
-
79955369537
-
The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension
-
21177701 1:CAS:528:DC%2BC3MXlt1Glsbg%3D 10.1093/cvr/cvq408
-
White K, Dempsie Y, Nilsen M, Wright AF, Loughlin L, MacLean MR (2011) The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension. Cardiovasc Res 90:373-382
-
(2011)
Cardiovasc Res
, vol.90
, pp. 373-382
-
-
White, K.1
Dempsie, Y.2
Nilsen, M.3
Wright, A.F.4
Loughlin, L.5
Maclean, M.R.6
-
54
-
-
77956404810
-
BMP signaling in vascular development and disease
-
20674464 1:CAS:528:DC%2BC3cXhtFGjsbfP 10.1016/j.cytogfr.2010.06.001
-
Lowery JW, de Caestecker MP (2010) BMP signaling in vascular development and disease. Cytokine Growth Factor Rev 21:287-298
-
(2010)
Cytokine Growth Factor Rev
, vol.21
, pp. 287-298
-
-
Lowery, J.W.1
De Caestecker, M.P.2
-
55
-
-
70649083092
-
Recent advances in BMP receptor signaling
-
19897402 1:CAS:528:DC%2BD1MXhsV2ms7fK 10.1016/j.cytogfr.2009.10.007
-
Sieber C, Kopf J, Hiepen C, Knaus P (2009) Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev 20:343-355
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, pp. 343-355
-
-
Sieber, C.1
Kopf, J.2
Hiepen, C.3
Knaus, P.4
-
56
-
-
0033838125
-
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
-
10903931 1:CAS:528:DC%2BD3cXms1Wgtro%3D 10.1086/303059
-
Deng Z, Morse JH, Slager SL, Cuervo N, Moore KJ, Venetos G, Kalachikov S, Cayanis E, Fischer SG, Barst RJ et al (2000) Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet 67:737-744
-
(2000)
Am J Hum Genet
, vol.67
, pp. 737-744
-
-
Deng, Z.1
Morse, J.H.2
Slager, S.L.3
Cuervo, N.4
Moore, K.J.5
Venetos, G.6
Kalachikov, S.7
Cayanis, E.8
Fischer, S.G.9
Barst, R.J.10
-
57
-
-
24644441189
-
Genetics of pulmonary arterial hypertension: Current and future implications
-
16121312 10.1055/s-2005-916150
-
Elliott CG (2005) Genetics of pulmonary arterial hypertension: current and future implications. Semin Respir Crit Care Med 26:365-371
-
(2005)
Semin Respir Crit Care Med
, vol.26
, pp. 365-371
-
-
Elliott, C.G.1
-
58
-
-
40049100690
-
Narrative review: The enigma of pulmonary arterial hypertension: New insights from genetic studies
-
18283205
-
Newman JH, Phillips JA, Loyd JE (2008) Narrative review: the enigma of pulmonary arterial hypertension: new insights from genetic studies. Ann Intern Med 148:278-283
-
(2008)
Ann Intern Med
, vol.148
, pp. 278-283
-
-
Newman, J.H.1
Phillips, J.A.2
Loyd, J.E.3
-
59
-
-
57349188499
-
Molecular mechanisms of pulmonary arterial hypertension: Role of mutations in the bone morphogenetic protein type II receptor
-
19059957 1:CAS:528:DC%2BD1MXps1elsA%3D%3D 10.1378/chest.08-1341
-
Davies RJ, Morrell NW (2008) Molecular mechanisms of pulmonary arterial hypertension: role of mutations in the bone morphogenetic protein type II receptor. Chest 134:1271-1277
-
(2008)
Chest
, vol.134
, pp. 1271-1277
-
-
Davies, R.J.1
Morrell, N.W.2
-
60
-
-
8644256840
-
BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia
-
15286002 1:CAS:528:DC%2BD2cXhtFShsLfK 10.1152/ajplung.00239.2004
-
Beppu H, Ichinose F, Kawai N, Jones RC, Yu PB, Zapol WM, Miyazono K, Li E, Bloch KD (2004) BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol Lung Cell Mol Physiol 287:L1241-L1247
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Beppu, H.1
Ichinose, F.2
Kawai, N.3
Jones, R.C.4
Yu, P.B.5
Zapol, W.M.6
Miyazono, K.7
Li, E.8
Bloch, K.D.9
-
61
-
-
23044504042
-
Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice
-
16027259 1:CAS:528:DC%2BD2MXmt1yht7k%3D 10.1161/CIRCULATIONAHA.104.492488
-
Song Y, Jones JE, Beppu H, Keaney JF, Loscalzo J, Zhang Y-Y (2005) Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice. Circulation 112:553-562
-
(2005)
Circulation
, vol.112
, pp. 553-562
-
-
Song, Y.1
Jones, J.E.2
Beppu, H.3
Keaney, J.F.4
Loscalzo, J.5
Zhang, Y.-Y.6
-
62
-
-
40749102181
-
Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature
-
18024717 1:CAS:528:DC%2BD1cXhtVWrtbk%3D 10.1152/ajplung.00034.2007
-
Frank DB, Lowery J, Anderson L, Brink M, Reese J, de Caestecker M (2008) Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature. Am J Physiol Lung Cell Mol Physiol 294:L98-L109
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Frank, D.B.1
Lowery, J.2
Anderson, L.3
Brink, M.4
Reese, J.5
De Caestecker, M.6
-
63
-
-
2342486700
-
Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle
-
15031260 1:CAS:528:DC%2BD2cXjt1ylu7w%3D 10.1161/01.RES.0000126047.82846. 20
-
West J, Fagan K, Steudel W, Fouty B, Lane K, Harral J, Hoedt-Miller M, Tada Y, Ozimek J, Tuder R et al (2004) Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circ Res 94:1109-1114
-
(2004)
Circ Res
, vol.94
, pp. 1109-1114
-
-
West, J.1
Fagan, K.2
Steudel, W.3
Fouty, B.4
Lane, K.5
Harral, J.6
Hoedt-Miller, M.7
Tada, Y.8
Ozimek, J.9
Tuder, R.10
-
64
-
-
0020135694
-
Membrane properties of smooth muscle cells in pulmonary hypertensive rats
-
6805338 1:CAS:528:DyaL38XhvFOnt7g%3D
-
Suzuki H, Twarog BM (1982) Membrane properties of smooth muscle cells in pulmonary hypertensive rats. Am J Physiol 242:H907-H915
-
(1982)
Am J Physiol
, vol.242
-
-
Suzuki, H.1
Twarog, B.M.2
-
65
-
-
79955558300
-
Theme: Hypoxia. Hypoxia and ion channel function
-
21178108 1:CAS:528:DC%2BC3MXmsFCmurc%3D 10.1152/ajpcell.00512.2010
-
Shimoda LA, Polak J (2011) Theme: Hypoxia. Hypoxia and ion channel function. Am J Physiol Cell Physiol 300(5):C951-C967
-
(2011)
Am J Physiol Cell Physiol
, vol.300
, Issue.5
-
-
Shimoda, L.A.1
Polak, J.2
-
66
-
-
0032491187
-
+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension
-
9760294 1:CAS:528:DyaK1cXmvFantLY%3D 10.1161/01.CIR.98.14.1400
-
+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension. Circulation 98:1400-1406
-
(1998)
Circulation
, vol.98
, pp. 1400-1406
-
-
Yuan, J.X.1
Aldinger, A.M.2
Juhaszova, M.3
Wang, J.4
Conte, Jr.J.V.5
Gaine, S.P.6
Orens, J.B.7
Rubin, L.J.8
-
67
-
-
40349110969
-
Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: Pharmacotherapeutic implications
-
18084317 1:CAS:528:DC%2BD1cXislSjtbs%3D
-
Burg ED, Remillard CV, Yuan JX (2008) Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications. Br J Pharmacol 153(Suppl 1):S99-S111
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 1
-
-
Burg, E.D.1
Remillard, C.V.2
Yuan, J.X.3
-
68
-
-
0037080541
-
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: Role of increased expression and activity of voltage-gated potassium channels
-
11790708 1:CAS:528:DC%2BD38XhsFeksL0%3D 10.1161/hc0202.101974
-
Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Moudgil R, Hopkins TA, Lopaschuk GD, Puttagunta L, Waite R, Archer SL (2002) Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels. Circulation 105:244-250
-
(2002)
Circulation
, vol.105
, pp. 244-250
-
-
Michelakis, E.D.1
McMurtry, M.S.2
Wu, X.C.3
Dyck, J.R.4
Moudgil, R.5
Hopkins, T.A.6
Lopaschuk, G.D.7
Puttagunta, L.8
Waite, R.9
Archer, S.L.10
-
69
-
-
33745155785
-
An abnormal mitochondrial-hypoxia inducible factor-1a-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: Similarities to human pulmonary arterial hypertension
-
16735674 1:CAS:528:DC%2BD28XltFWgtbk%3D 10.1161/CIRCULATIONAHA.105.609008
-
Bonnet S, Michelakis ED, Porter CJ, Andrade-Navarro MA, Thebaud B, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry MS et al (2006) An abnormal mitochondrial-hypoxia inducible factor-1a-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension. Circulation 113:2630-2641
-
(2006)
Circulation
, vol.113
, pp. 2630-2641
-
-
Bonnet, S.1
Michelakis, E.D.2
Porter, C.J.3
Andrade-Navarro, M.A.4
Thebaud, B.5
Bonnet, S.6
Haromy, A.7
Harry, G.8
Moudgil, R.9
McMurtry, M.S.10
-
70
-
-
0032492407
-
+ channel gene transcription in primary pulmonary hypertension
-
9504523 1:STN:280:DyaK1c7mtlSmsw%3D%3D 10.1016/S0140-6736(05)78495-6
-
+ channel gene transcription in primary pulmonary hypertension. Lancet 351:726-727
-
(1998)
Lancet
, vol.351
, pp. 726-727
-
-
Yuan, X.J.1
Wang, J.2
Juhaszova, M.3
Gaine, S.P.4
Rubin, L.J.5
-
71
-
-
34547456414
-
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
-
17596340 1:CAS:528:DC%2BD2sXnvFOms7g%3D 10.1073/pnas.0610467104
-
Bonnet S, Rochefort G, Sutendra G, Archer SL, Haromy A, Webster L, Hashimoto K, Bonnet SN, Michelakis ED (2007) The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci U S A 104:11418-11423
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11418-11423
-
-
Bonnet, S.1
Rochefort, G.2
Sutendra, G.3
Archer, S.L.4
Haromy, A.5
Webster, L.6
Hashimoto, K.7
Bonnet, S.N.8
Michelakis, E.D.9
-
72
-
-
0037461359
-
2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats
-
12695303 1:CAS:528:DC%2BD3sXivVClu78%3D 10.1161/01.CIR.0000062688.76508. B3
-
2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats. Circulation 107:2037-2044
-
(2003)
Circulation
, vol.107
, pp. 2037-2044
-
-
Pozeg, Z.I.1
Michelakis, E.D.2
McMurtry, M.S.3
Thebaud, B.4
Wu, X.C.5
Dyck, J.R.6
Hashimoto, K.7
Wang, S.8
Moudgil, R.9
Harry, G.10
-
75
-
-
4444352981
-
2+ channels in pulmonary arterial smooth muscle cells: A novel mechanism of hypoxic pulmonary hypertension
-
15256480 1:CAS:528:DC%2BD2cXntVCrtLw%3D 10.1161/01.RES.0000138952.16382. ad
-
2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension. Circ Res 95:496-505
-
(2004)
Circ Res
, vol.95
, pp. 496-505
-
-
Lin, M.J.1
Leung, G.P.2
Zhang, W.M.3
Yang, X.R.4
Yip, K.P.5
Tse, C.M.6
Sham, J.S.7
-
76
-
-
0026632785
-
The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
-
1603139 1:STN:280:DyaK383ptlaksQ%3D%3D 10.1056/NEJM199207093270203
-
Rich S, Kaufmann E, Levy PS (1992) The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 327:76-81
-
(1992)
N Engl J Med
, vol.327
, pp. 76-81
-
-
Rich, S.1
Kaufmann, E.2
Levy, P.S.3
-
77
-
-
20544448927
-
Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
-
15939821 1:CAS:528:DC%2BD2MXkvVCmu74%3D 10.1161/CIRCULATIONAHA.104.488486
-
Sitbon O, Humbert M, Jais X, Ioos V, Hamid AM, Provencher S, Garcia G, Parent F, Herve P, Simonneau G (2005) Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 111:3105-3111
-
(2005)
Circulation
, vol.111
, pp. 3105-3111
-
-
Sitbon, O.1
Humbert, M.2
Jais, X.3
Ioos, V.4
Hamid, A.M.5
Provencher, S.6
Garcia, G.7
Parent, F.8
Herve, P.9
Simonneau, G.10
-
78
-
-
0041422166
-
Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension
-
12878719 1:CAS:528:DC%2BD3sXmtlykurg%3D 10.1073/pnas.1633724100
-
Bonnet S, Dumas-de-La-Roque E, Begueret H, Marthan R, Fayon M, Dos Santos P, Savineau JP, Baulieu EE (2003) Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension. Proc Natl Acad Sci U S A 100:9488-9493
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9488-9493
-
-
Bonnet, S.1
Dumas-De-La-Roque, E.2
Begueret, H.3
Marthan, R.4
Fayon, M.5
Dos Santos, P.6
Savineau, J.P.7
Baulieu, E.E.8
-
79
-
-
6344257102
-
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
-
15375007 1:CAS:528:DC%2BD2cXot1aitr8%3D 10.1161/01.RES.0000145360.16770. 9f
-
McMurtry MS, Bonnet S, Wu X, Dyck JR, Haromy A, Hashimoto K, Michelakis ED (2004) Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ Res 95:830-840
-
(2004)
Circ Res
, vol.95
, pp. 830-840
-
-
McMurtry, M.S.1
Bonnet, S.2
Wu, X.3
Dyck, J.R.4
Haromy, A.5
Hashimoto, K.6
Michelakis, E.D.7
-
81
-
-
2342483718
-
Calcium and TRP channels in pulmonary vascular smooth muscle cell proliferation
-
15016901 1:CAS:528:DC%2BD2cXjslyktbg%3D
-
Landsberg JW, Yuan JX (2004) Calcium and TRP channels in pulmonary vascular smooth muscle cell proliferation. News Physiol Sci 19:44-50
-
(2004)
News Physiol Sci
, vol.19
, pp. 44-50
-
-
Landsberg, J.W.1
Yuan, J.X.2
-
82
-
-
84865137448
-
Hypoxia-induced migration in pulmonary arterial smooth muscle cells requires calcium-dependent upregulation of aquaporin 1
-
22683574 1:CAS:528:DC%2BC38XhtlSksr%2FO 10.1152/ajplung.00130.2012
-
Leggett K, Maylor J, Undem C, Lai N, Lu W, Schweitzer KS, King LS, Myers AC, Sylvester JT, Sidhaye VK et al (2012) Hypoxia-induced migration in pulmonary arterial smooth muscle cells requires calcium-dependent upregulation of aquaporin 1. Am J Physiol Lung Cell Mol Physiol 303:L343-L353
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Leggett, K.1
Maylor, J.2
Undem, C.3
Lai, N.4
Lu, W.5
Schweitzer, K.S.6
King, L.S.7
Myers, A.C.8
Sylvester, J.T.9
Sidhaye, V.K.10
-
83
-
-
83655197507
-
2+ entry and TRPC channel expression in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats
-
21940663 1:CAS:528:DC%2BC38XhvVKqsro%3D 10.1152/ajpcell.00247.2011
-
2+ entry and TRPC channel expression in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats. Am J Physiol Cell Physiol 302:C77-C87
-
(2012)
Am J Physiol Cell Physiol
, vol.302
-
-
Liu, X.R.1
Zhang, M.F.2
Yang, N.3
Liu, Q.4
Wang, R.X.5
Cao, Y.N.6
Yang, X.R.7
Sham, J.S.8
Lin, M.J.9
-
84
-
-
84855317520
-
STIM2 contributes to enhanced store-operated Ca entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension
-
21709766 1:CAS:528:DC%2BC3MXpsVantb0%3D
-
Song MY, Makino A, Yuan JX (2011) STIM2 contributes to enhanced store-operated Ca entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Pulm Circ 1:84-94
-
(2011)
Pulm Circ
, vol.1
, pp. 84-94
-
-
Song, M.Y.1
Makino, A.2
Yuan, J.X.3
-
86
-
-
57049147057
-
Upregulation of vascular calcium channels in neonatal piglets with hypoxia-induced pulmonary hypertension
-
10.1152/ajplung.90286.2008 1:CAS:528:DC%2BD1cXhsVWku7jO
-
Hirenallur SD, Haworth ST, Leming JT, Chang J, Hernandez G, Gordon JB, Rusch NJ (2008) Upregulation of vascular calcium channels in neonatal piglets with hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 295:L915-L924
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Hirenallur, S.D.1
Haworth, S.T.2
Leming, J.T.3
Chang, J.4
Hernandez, G.5
Gordon, J.B.6
Rusch, N.J.7
-
87
-
-
20944438626
-
Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes
-
15774856 1:CAS:528:DC%2BD2MXjsFagsLo%3D 10.1161/01.RES.0000163066.07472. ff
-
Rodman DM, Reese K, Harral J, Fouty B, Wu S, West J, Hoedt-Miller M, Tada Y, Li KX, Cool C et al (2005) Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes. Circ Res 96:864-872
-
(2005)
Circ Res
, vol.96
, pp. 864-872
-
-
Rodman, D.M.1
Reese, K.2
Harral, J.3
Fouty, B.4
Wu, S.5
West, J.6
Hoedt-Miller, M.7
Tada, Y.8
Li, K.X.9
Cool, C.10
-
88
-
-
2442542398
-
Regulation of TRPC6 channel activity by tyrosine phosphorylation
-
14761972 1:CAS:528:DC%2BD2cXjsVKmtrw%3D 10.1074/jbc.M311274200
-
Hisatsune C, Kuroda Y, Nakamura K, Inoue T, Nakamura T, Michikawa T, Mizutani A, Mikoshiba K (2004) Regulation of TRPC6 channel activity by tyrosine phosphorylation. J Biol Chem 279:18887-18894
-
(2004)
J Biol Chem
, vol.279
, pp. 18887-18894
-
-
Hisatsune, C.1
Kuroda, Y.2
Nakamura, K.3
Inoue, T.4
Nakamura, T.5
Michikawa, T.6
Mizutani, A.7
Mikoshiba, K.8
-
89
-
-
27844586833
-
EGF induces tyrosine phosphorylation, membrane insertion and activation of transient receptor potential channel 4
-
16144838 1:CAS:528:DC%2BD2MXhtF2is7%2FI 10.1074/jbc.M503646200
-
Odell AF, Scott JL, Van Helden DF (2005) EGF induces tyrosine phosphorylation, membrane insertion and activation of transient receptor potential channel 4. J Biol Chem 280:37974-37987
-
(2005)
J Biol Chem
, vol.280
, pp. 37974-37987
-
-
Odell, A.F.1
Scott, J.L.2
Van Helden, D.F.3
-
91
-
-
4644290321
-
Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension
-
15358862 1:CAS:528:DC%2BD2cXotVygtbo%3D 10.1073/pnas.0405908101
-
Yu Y, Fantozzi I, Remillard CV, Landsberg JW, Kunichika N, Platoshyn O, Tigno DD, Thistlethwaite PA, Rubin LJ, Yuan JX (2004) Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Proc Natl Acad Sci U S A 101:13861-13866
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13861-13866
-
-
Yu, Y.1
Fantozzi, I.2
Remillard, C.V.3
Landsberg, J.W.4
Kunichika, N.5
Platoshyn, O.6
Tigno, D.D.7
Thistlethwaite, P.A.8
Rubin, L.J.9
Yuan, J.X.10
-
92
-
-
8444223158
-
Bosentan inhibits transient receptor potential channel expression in pulmonary vascular myocytes
-
15317671 10.1164/rccm.200312-1668OC
-
Kunichika N, Landsberg JW, Yu Y, Kunichika H, Thistlethwaite PA, Rubin LJ, Yuan JX (2004) Bosentan inhibits transient receptor potential channel expression in pulmonary vascular myocytes. Am J Respir Crit Care Med 170:1101-1107
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1101-1107
-
-
Kunichika, N.1
Landsberg, J.W.2
Yu, Y.3
Kunichika, H.4
Thistlethwaite, P.A.5
Rubin, L.J.6
Yuan, J.X.7
-
93
-
-
66349095797
-
A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension
-
19380626 1:CAS:528:DC%2BD1MXltV2jsrk%3D 10.1161/CIRCULATIONAHA.108.782458
-
Yu Y, Keller SH, Remillard CV, Safrina O, Nicholson A, Zhang SL, Jiang W, Vangala N, Landsberg JW, Wang JY et al (2009) A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension. Circulation 119:2313-2322
-
(2009)
Circulation
, vol.119
, pp. 2313-2322
-
-
Yu, Y.1
Keller, S.H.2
Remillard, C.V.3
Safrina, O.4
Nicholson, A.5
Zhang, S.L.6
Jiang, W.7
Vangala, N.8
Landsberg, J.W.9
Wang, J.Y.10
-
94
-
-
73649120970
-
Sildenafil inhibits chronically hypoxic upregulation of canonical transient receptor potential expression in rat pulmonary arterial smooth muscle
-
19889962 1:CAS:528:DC%2BC3cXhsFKmtrg%3D 10.1152/ajpcell.00629.2008
-
Lu W, Ran P, Zhang D, Peng G, Li B, Zhong N, Wang J (2010) Sildenafil inhibits chronically hypoxic upregulation of canonical transient receptor potential expression in rat pulmonary arterial smooth muscle. Am J Physiol Cell Physiol 298:C114-C123
-
(2010)
Am J Physiol Cell Physiol
, vol.298
-
-
Lu, W.1
Ran, P.2
Zhang, D.3
Peng, G.4
Li, B.5
Zhong, N.6
Wang, J.7
-
95
-
-
21544444144
-
Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells
-
15817798 10.1164/rccm.200411-1587OC
-
Wharton J, Strange JW, Moller GM, Growcott EJ, Ren X, Franklyn AP, Phillips SC, Wilkins MR (2005) Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells. Am J Respir Crit Care Med 172:105-113
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 105-113
-
-
Wharton, J.1
Strange, J.W.2
Moller, G.M.3
Growcott, E.J.4
Ren, X.5
Franklyn, A.P.6
Phillips, S.C.7
Wilkins, M.R.8
-
96
-
-
84871788547
-
Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension
-
23139294 1:CAS:528:DC%2BC38XhvVeltrbN 10.1161/ATVBAHA.112.300121
-
Yang J, Li X, Al-Lamki R, Wu C, Weiss A, Berk J, Schermuly RT, Morrell NW (2013) Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension. Arterioscler Thromb Vasc Biol 33:34-42
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 34-42
-
-
Yang, J.1
Li, X.2
Al-Lamki, R.3
Wu, C.4
Weiss, A.5
Berk, J.6
Schermuly, R.T.7
Morrell, N.W.8
-
97
-
-
28444461454
-
Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension
-
16205723 1:CAS:528:DC%2BD2MXht1Ghu7vP 10.1038/sj.bjp.0706408
-
Guilluy C, Sauzeau V, Rolli-Derkinderen M, Guerin P, Sagan C, Pacaud P, Loirand G (2005) Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension. Br J Pharmacol 146:1010-1018
-
(2005)
Br J Pharmacol
, vol.146
, pp. 1010-1018
-
-
Guilluy, C.1
Sauzeau, V.2
Rolli-Derkinderen, M.3
Guerin, P.4
Sagan, C.5
Pacaud, P.6
Loirand, G.7
-
99
-
-
78649892620
-
MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration
-
20693317 1:CAS:528:DC%2BC3cXhs1aitrrJ 10.1152/ajplung.00201.2010
-
Sarkar J, Gou D, Turaka P, Viktorova E, Ramchandran R, Raj JU (2010) MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration. Am J Physiol Lung Cell Mol Physiol 299:L861-L871
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.299
-
-
Sarkar, J.1
Gou, D.2
Turaka, P.3
Viktorova, E.4
Ramchandran, R.5
Raj, J.U.6
-
100
-
-
84861589157
-
Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia
-
22539766 1:CAS:528:DC%2BC38XnsVCju7o%3D 10.1161/CIRCRESAHA.112.264473
-
Wojciak-Stothard B, Zhao L, Oliver E, Dubois O, Wu Y, Kardassis D, Vasilaki E, Huang M, Mitchell JA, Harrington LS et al (2012) Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia. Circ Res 110:1423-1434
-
(2012)
Circ Res
, vol.110
, pp. 1423-1434
-
-
Wojciak-Stothard, B.1
Zhao, L.2
Oliver, E.3
Dubois, O.4
Wu, Y.5
Kardassis, D.6
Vasilaki, E.7
Huang, M.8
Mitchell, J.A.9
Harrington, L.S.10
-
101
-
-
84866739116
-
Involvement of TRPV1 and TRPV4 channels in migration of rat pulmonary arterial smooth muscle cells
-
22820913 1:CAS:528:DC%2BC38Xht1aisbbN 10.1007/s00424-012-1136-5
-
Martin E, Dahan D, Cardouat G, Gillibert-Duplantier J, Marthan R, Savineau JP, Ducret T (2012) Involvement of TRPV1 and TRPV4 channels in migration of rat pulmonary arterial smooth muscle cells. Pflugers Arch 464:261-272
-
(2012)
Pflugers Arch
, vol.464
, pp. 261-272
-
-
Martin, E.1
Dahan, D.2
Cardouat, G.3
Gillibert-Duplantier, J.4
Marthan, R.5
Savineau, J.P.6
Ducret, T.7
-
102
-
-
17144379334
-
Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption
-
15815633 1:CAS:528:DC%2BD2MXivFCgurs%3D 10.1038/nature03460
-
Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman AS (2005) Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature 434:786-792
-
(2005)
Nature
, vol.434
, pp. 786-792
-
-
Saadoun, S.1
Papadopoulos, M.C.2
Hara-Chikuma, M.3
Verkman, A.S.4
-
103
-
-
67650230936
-
AQP1 is not only a water channel: It contributes to cell migration through Lin7/beta-catenin
-
19584911 10.1371/journal.pone.0006167 1:CAS:528:DC%2BD1MXosFOmtr8%3D
-
Monzani E, Bazzotti R, Perego C, La Porta CA (2009) AQP1 is not only a water channel: it contributes to cell migration through Lin7/beta-catenin. PLoS One 4:e6167
-
(2009)
PLoS One
, vol.4
, pp. 6167
-
-
Monzani, E.1
Bazzotti, R.2
Perego, C.3
La Porta, C.A.4
-
106
-
-
0035024643
-
Ion exchange activity in pulmonary artery smooth muscle cells: The response to hypoxia
-
11159005 1:CAS:528:DC%2BD3MXjtVajtrk%3D
-
Madden JA, Ray DE, Keller PA, Kleinman JG (2001) Ion exchange activity in pulmonary artery smooth muscle cells: the response to hypoxia. Am J Physiol Lung Cell Mol Physiol 280:L264-L271
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.280
-
-
Madden, J.A.1
Ray, D.E.2
Keller, P.A.3
Kleinman, J.G.4
-
108
-
-
0030077602
-
+ exchange and growth factors in pulmonary artery smooth muscle cell proliferation
-
8630263 1:CAS:528:DyaK28Xps12hug%3D%3D
-
+ exchange and growth factors in pulmonary artery smooth muscle cell proliferation. Am J Respir Cell Mol Biol 14:139-145
-
(1996)
Am J Respir Cell Mol Biol
, vol.14
, pp. 139-145
-
-
Quinn, D.A.1
Dahlberg, C.G.2
Bonventre, J.P.3
Scheid, C.R.4
Honeyman, T.5
Joseph, P.M.6
Thompson, B.T.7
Hales, C.A.8
-
110
-
-
33751117499
-
HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes
-
16766575 1:CAS:528:DC%2BD28Xht1GnsLrJ 10.1152/ajplung.00528.2005
-
Shimoda LA, Fallon M, Pisarcik S, Wang J, Semenza GL (2006) HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes. Am J Physiol Lung Cell Mol Physiol 291:L941-L949
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Shimoda, L.A.1
Fallon, M.2
Pisarcik, S.3
Wang, J.4
Semenza, G.L.5
-
111
-
-
0031956840
-
Amiloride analogs inhibit chronic hypoxic pulmonary hypertension
-
9563749 1:STN:280:DyaK1c3itlagug%3D%3D
-
Quinn DA, Du HK, Thompson BT, Hales CA (1998) Amiloride analogs inhibit chronic hypoxic pulmonary hypertension. Am J Respir Crit Care Med 157:1263-1268
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1263-1268
-
-
Quinn, D.A.1
Du, H.K.2
Thompson, B.T.3
Hales, C.A.4
-
112
-
-
44449095608
-
Deficiency of the NHE1 gene prevents hypoxia-induced pulmonary hypertension and vascular remodeling
-
18310478 1:CAS:528:DC%2BD1cXns1KgsL0%3D 10.1164/rccm.200710-1522OC
-
Yu L, Quinn DA, Garg HG, Hales CA (2008) Deficiency of the NHE1 gene prevents hypoxia-induced pulmonary hypertension and vascular remodeling. Am J Respir Crit Care Med 177:1276-1284
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 1276-1284
-
-
Yu, L.1
Quinn, D.A.2
Garg, H.G.3
Hales, C.A.4
-
113
-
-
80555143052
-
Silencing of NHE1 attenuates PASMC proliferation, hypertrophy and migration via E2F1
-
21454803 1:CAS:528:DC%2BC3MXhsV2nsbjO 10.1165/rcmb.2011-0032OC
-
Yu L, Hales CA (2011) Silencing of NHE1 attenuates PASMC proliferation, hypertrophy and migration via E2F1. Am J Respir Cell Mol Biol 45:923-930
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 923-930
-
-
Yu, L.1
Hales, C.A.2
-
114
-
-
0031689058
-
+ antiport activity, isoform expression, and localization in endothelial cells
-
9728038 1:CAS:528:DyaK1cXmtFSqu7c%3D
-
+ antiport activity, isoform expression, and localization in endothelial cells. Am J Physiol 275:L442-L451
-
(1998)
Am J Physiol
, vol.275
-
-
Cutaia, M.V.1
Parks, N.2
Centracchio, J.3
Rounds, S.4
Yip, K.P.5
Sun, A.M.6
-
115
-
-
0029034799
-
Hypoxia induces capillary network formation in cultured bovine pulmonary microvessel endothelial cells
-
7539223 1:CAS:528:DyaK2MXlvVaisbc%3D
-
Phillips PG, Birnby LM, Narendran A (1995) Hypoxia induces capillary network formation in cultured bovine pulmonary microvessel endothelial cells. Am J Physiol 268:L789-L800
-
(1995)
Am J Physiol
, vol.268
-
-
Phillips, P.G.1
Birnby, L.M.2
Narendran, A.3
-
117
-
-
84875710070
-
+ exchange regulatory factor 1 in hypoxic pulmonary arterial smooth muscle cells
-
Abstract
-
+ exchange regulatory factor 1 in hypoxic pulmonary arterial smooth muscle cells. FASEB J 24:1023.4, Abstract
-
(2010)
FASEB J
, vol.24
, pp. 10234
-
-
Maylor, J.1
Lu, W.2
Pisarcik, S.3
Walker, J.4
Undem, C.5
Myers, A.6
Shimoda, L.7
-
118
-
-
40749126460
-
Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: Results of the EXPEDITION study
-
18355507 10.1016/j.athoracsur.2007.10.054
-
Mentzer RM Jr, Bartels C, Bolli R, Boyce S, Buckberg GD, Chaitman B, Haverich A, Knight J, Menasche P, Myers ML et al (2008) Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study. Ann Thorac Surg 85:1261-1270
-
(2008)
Ann Thorac Surg
, vol.85
, pp. 1261-1270
-
-
Mentzer, Jr.R.M.1
Bartels, C.2
Bolli, R.3
Boyce, S.4
Buckberg, G.D.5
Chaitman, B.6
Haverich, A.7
Knight, J.8
Menasche, P.9
Myers, M.L.10
-
119
-
-
58149291690
-
Why did the NHE inhibitor clinical trials fail?
-
19027021 1:CAS:528:DC%2BD1MXntVGmtA%3D%3D 10.1016/j.yjmcc.2008.09.715
-
Murphy E, Allen DG (2009) Why did the NHE inhibitor clinical trials fail? J Mol Cell Cardiol 46:137-141
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 137-141
-
-
Murphy, E.1
Allen, D.G.2
-
120
-
-
34147189502
-
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats
-
17332430 1:CAS:528:DC%2BD2sXjtlWmsLg%3D 10.1161/01.RES.0000261658.12024. 18
-
Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, McMurtry IF (2007) Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circ Res 100:923-929
-
(2007)
Circ Res
, vol.100
, pp. 923-929
-
-
Oka, M.1
Homma, N.2
Taraseviciene-Stewart, L.3
Morris, K.G.4
Kraskauskas, D.5
Burns, N.6
Voelkel, N.F.7
McMurtry, I.F.8
-
121
-
-
66049112085
-
Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: New findings for an old problem
-
19297247 1:CAS:528:DC%2BD1MXms1OgsrY%3D 10.1016/j.coph.2009.02.006
-
Ward JPT, Mcmurtry IF (2009) Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem. Curr Opin Pharmacol 9:287-296
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 287-296
-
-
Ward, J.P.T.1
McMurtry, I.F.2
-
122
-
-
84864566286
-
Animal models of pulmonary hypertension: Rho kinase inhibition
-
22713173 1:CAS:528:DC%2BC38XhtFKnsrbO 10.1016/j.pbiomolbio.2012.05.009
-
Firth AL, Choi I-W, Park WS (2012) Animal models of pulmonary hypertension: Rho kinase inhibition. Prog Biophys Mol Biol 109:67-75
-
(2012)
Prog Biophys Mol Biol
, vol.109
, pp. 67-75
-
-
Firth, A.L.1
Choi, I.-W.2
Park, W.S.3
-
123
-
-
53849089211
-
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
-
18536743 1:CAS:528:DC%2BD1cXht1emurzK 10.1038/bjp.2008.239
-
Oka M, Fagan KA, Jones PL, McMurtry IF (2008) Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension. Br J Pharmacol 155:444-454
-
(2008)
Br J Pharmacol
, vol.155
, pp. 444-454
-
-
Oka, M.1
Fagan, K.A.2
Jones, P.L.3
McMurtry, I.F.4
-
124
-
-
35348967735
-
BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes
-
17600318 1:CAS:528:DC%2BD2sXhtlWhsr3N 10.1165/rcmb.2006-0360OC
-
Yang X, Lee PJ, Long L, Trembath RC, Morrell NW (2007) BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes. Am J Respir Cell Mol Biol 37:598-605
-
(2007)
Am J Respir Cell Mol Biol
, vol.37
, pp. 598-605
-
-
Yang, X.1
Lee, P.J.2
Long, L.3
Trembath, R.C.4
Morrell, N.W.5
-
125
-
-
33947715935
-
Mechanisms of vascular smooth muscle cell migration
-
17363707 1:CAS:528:DC%2BD2sXisFyntL8%3D 10.1161/01.RES.0000258492.96097. 47
-
Gerthoffer WT (2007) Mechanisms of vascular smooth muscle cell migration. Circ Res 100:607-621
-
(2007)
Circ Res
, vol.100
, pp. 607-621
-
-
Gerthoffer, W.T.1
-
126
-
-
4644248958
-
Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin
-
15297378 1:CAS:528:DC%2BD2cXntlyjtLc%3D 10.1161/01.RES.0000141428.53262. a4
-
Liu Y, Suzuki YJ, Day RM, Fanburg BL (2004) Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin. Circ Res 95:579-586
-
(2004)
Circ Res
, vol.95
, pp. 579-586
-
-
Liu, Y.1
Suzuki, Y.J.2
Day, R.M.3
Fanburg, B.L.4
-
127
-
-
84866995187
-
+ exchange activity in murine pulmonary arterial smooth muscle cells via Rho kinase
-
23029469 1:CAS:528:DC%2BC38XhsFShsL%2FJ 10.1371/journal.pone.0046303
-
+ exchange activity in murine pulmonary arterial smooth muscle cells via Rho kinase. PLoS One 7:e46303
-
(2012)
PLoS One
, vol.7
, pp. 46303
-
-
Undem, C.1
Rios, E.J.2
Maylor, J.3
Shimoda, L.A.4
-
128
-
-
14244260105
-
Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension
-
15710736 1:STN:280:DC%2BD2M%2FotFOhtw%3D%3D 10.1136/hrt.2003.029470
-
Fukumoto Y, Matoba T, Ito A, Tanaka H, Kishi T, Hayashidani S, Abe K, Takeshita A, Shimokawa H (2005) Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart 91:391-392
-
(2005)
Heart
, vol.91
, pp. 391-392
-
-
Fukumoto, Y.1
Matoba, T.2
Ito, A.3
Tanaka, H.4
Kishi, T.5
Hayashidani, S.6
Abe, K.7
Takeshita, A.8
Shimokawa, H.9
-
129
-
-
31644431508
-
Beneficial acute effects of Rho-kinase inhibitor in patients with pulmonary arterial hypertension
-
16434811 1:CAS:528:DC%2BD28XhsFyqurY%3D 10.1253/circj.70.174
-
Ishikura K, Yamada N, Ito M, Ota S, Nakamura M, Isaka N, Nakano T (2006) Beneficial acute effects of Rho-kinase inhibitor in patients with pulmonary arterial hypertension. Circ J 70:174-178
-
(2006)
Circ J
, vol.70
, pp. 174-178
-
-
Ishikura, K.1
Yamada, N.2
Ito, M.3
Ota, S.4
Nakamura, M.5
Isaka, N.6
Nakano, T.7
-
130
-
-
15944403568
-
Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension
-
15563635 10.1164/rccm.200405-637OC
-
Nagaoka T, Fagan KA, Gebb SA, Morris KG, Suzuki T, Shimokawa H, McMurtry IF, Oka M (2005) Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. Am J Respir Crit Care Med 171:494-499
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 494-499
-
-
Nagaoka, T.1
Fagan, K.A.2
Gebb, S.A.3
Morris, K.G.4
Suzuki, T.5
Shimokawa, H.6
McMurtry, I.F.7
Oka, M.8
-
131
-
-
77950921360
-
Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension
-
10.1007/s00380-009-1176-8
-
Fujita H, Fukumoto Y, Saji K, Sugimura K, Demachi J, Nawata J, Shimokawa H (2010) Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension. Hear Vessel 25:144-149
-
(2010)
Hear Vessel
, vol.25
, pp. 144-149
-
-
Fujita, H.1
Fukumoto, Y.2
Saji, K.3
Sugimura, K.4
Demachi, J.5
Nawata, J.6
Shimokawa, H.7
-
132
-
-
4544388803
-
Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase
-
14977625 1:CAS:528:DC%2BD2cXptVyhs7k%3D 10.1152/ajplung.00090.2003
-
Fagan KA, Oka M, Bauer NR, Gebb SA, Ivy DD, Morris KG, McMurtry IF (2004) Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am J Physiol Lung Cell Mol Physiol 287:L656-L664
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Fagan, K.A.1
Oka, M.2
Bauer, N.R.3
Gebb, S.A.4
Ivy, D.D.5
Morris, K.G.6
McMurtry, I.F.7
-
133
-
-
10744222390
-
Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats
-
14670839 1:CAS:528:DC%2BD2cXhtFWlu7o%3D 10.1161/01.RES.0000111804.34509. 94
-
Abe K, Shimokawa H, Morikawa K, Uwatoku T, Oi K, Matsumoto Y, Hattori T, Nakashima Y, Kaibuchi K, Sueishi K et al (2004) Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats. Circ Res 94:385-393
-
(2004)
Circ Res
, vol.94
, pp. 385-393
-
-
Abe, K.1
Shimokawa, H.2
Morikawa, K.3
Uwatoku, T.4
Oi, K.5
Matsumoto, Y.6
Hattori, T.7
Nakashima, Y.8
Kaibuchi, K.9
Sueishi, K.10
-
134
-
-
34447576415
-
Regression of chronic hypoxic pulmonary hypertension by simvastatin
-
17277047 1:CAS:528:DC%2BD2sXls1yhs7k%3D 10.1152/ajplung.00411.2006
-
Girgis RE, Mozammel S, Champion HC, Li D, Peng X, Shimoda LA, Tuder RM, Johns RA, Hassoun PM (2007) Regression of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Lung Cell Mol Physiol 292:L1105-L1110
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Girgis, R.E.1
Mozammel, S.2
Champion, H.C.3
Li, D.4
Peng, X.5
Shimoda, L.A.6
Tuder, R.M.7
Johns, R.A.8
Hassoun, P.M.9
-
135
-
-
0035859940
-
Altered growth responses of pulmonary artery smooth muscle cells from
-
11502704 1:CAS:528:DC%2BD3MXmsVOgur8%3D 10.1161/hc3201.094152
-
Morrell NW, Yang X, Upton PD, Jourdan KB, Morgan N, Sheares KK, Trembath RC (2001) Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-β1 and bone morphogenetic proteins. Circulation 104:790-795
-
(2001)
Circulation
, vol.104
, pp. 790-795
-
-
Morrell, N.W.1
Yang, X.2
Upton, P.D.3
Jourdan, K.B.4
Morgan, N.5
Sheares, K.K.6
Trembath, R.C.7
-
137
-
-
20344362689
-
Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension
-
15845886 1:CAS:528:DC%2BD2MXktlKku78%3D 10.1161/01.RES.0000166926.54293. 68
-
Yang X, Long L, Southwood M, Rudarakanchana N, Upton PD, Jeffery TK, Atkinson C, Chen H, Trembath RC, Morrell NW (2005) Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension. Circ Res 96:1053-1063
-
(2005)
Circ Res
, vol.96
, pp. 1053-1063
-
-
Yang, X.1
Long, L.2
Southwood, M.3
Rudarakanchana, N.4
Upton, P.D.5
Jeffery, T.K.6
Atkinson, C.7
Chen, H.8
Trembath, R.C.9
Morrell, N.W.10
-
138
-
-
77749328893
-
Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension
-
20042692 1:CAS:528:DC%2BC3cXjsFGntLw%3D 10.1152/ajpregu.00534.2009
-
Anderson L, Lowery JW, Frank DB, Novitskaya T, Jones M, Mortlock DP, Chandler RL, de Caestecker MP (2010) Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension. Am J Physiol Regul Integr Comp Physiol 298:R833-R842
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
-
-
Anderson, L.1
Lowery, J.W.2
Frank, D.B.3
Novitskaya, T.4
Jones, M.5
Mortlock, D.P.6
Chandler, R.L.7
De Caestecker, M.P.8
-
139
-
-
24744471858
-
Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension
-
16100039 1:CAS:528:DC%2BD2MXpsVWrur0%3D 10.1161/01.RES.0000181152.65534. 07
-
Frank DB, Abtahi A, Yamaguchi DJ, Manning S, Shyr Y, Pozzi A, Baldwin HS, Johnson JE, de Caestecker MP (2005) Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension. Circ Res 97:496-504
-
(2005)
Circ Res
, vol.97
, pp. 496-504
-
-
Frank, D.B.1
Abtahi, A.2
Yamaguchi, D.J.3
Manning, S.4
Shyr, Y.5
Pozzi, A.6
Baldwin, H.S.7
Johnson, J.E.8
De Caestecker, M.P.9
-
140
-
-
0037421604
-
Signaling molecules in nonfamilial pulmonary hypertension
-
12571257 1:CAS:528:DC%2BD3sXovVKmug%3D%3D 10.1056/NEJMoa021650
-
Du L, Sullivan CC, Chu D, Cho AJ, Kido M, Wolf PL, Yuan JX, Deutsch R, Jamieson SW, Thistlethwaite PA (2003) Signaling molecules in nonfamilial pulmonary hypertension. N Engl J Med 348:500-509
-
(2003)
N Engl J Med
, vol.348
, pp. 500-509
-
-
Du, L.1
Sullivan, C.C.2
Chu, D.3
Cho, A.J.4
Kido, M.5
Wolf, P.L.6
Yuan, J.X.7
Deutsch, R.8
Jamieson, S.W.9
Thistlethwaite, P.A.10
-
141
-
-
33644958041
-
Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension
-
16361357 1:CAS:528:DC%2BD28Xjt1Skt78%3D 10.1152/ajplung.00206.2005
-
Takahashi H, Goto N, Kojima Y, Tsuda Y, Morio Y, Muramatsu M, Fukuchi Y (2006) Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 290:L450-L458
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Takahashi, H.1
Goto, N.2
Kojima, Y.3
Tsuda, Y.4
Morio, Y.5
Muramatsu, M.6
Fukuchi, Y.7
-
142
-
-
33644865928
-
Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: Implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension
-
16357305 1:CAS:528:DC%2BD28Xnt1CqsA%3D%3D 10.1161/01.RES.0000200180. 01710.e6
-
Teichert-Kuliszewska K, Kutryk MJ, Kuliszewski MA, Karoubi G, Courtman DW, Zucco L, Granton J, Stewart DJ (2006) Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension. Circ Res 98:209-217
-
(2006)
Circ Res
, vol.98
, pp. 209-217
-
-
Teichert-Kuliszewska, K.1
Kutryk, M.J.2
Kuliszewski, M.A.3
Karoubi, G.4
Courtman, D.W.5
Zucco, L.6
Granton, J.7
Stewart, D.J.8
-
143
-
-
80053020850
-
Bone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation
-
21808054 1:CAS:528:DC%2BC3MXhtFOit77P 10.1074/jbc.M111.274100
-
Gangopahyay A, Oran M, Bauer EM, Wertz JW, Comhair SA, Erzurum SC, Bauer PM (2011) Bone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation. J Biol Chem 286:33134-33140
-
(2011)
J Biol Chem
, vol.286
, pp. 33134-33140
-
-
Gangopahyay, A.1
Oran, M.2
Bauer, E.M.3
Wertz, J.W.4
Comhair, S.A.5
Erzurum, S.C.6
Bauer, P.M.7
-
144
-
-
28144440031
-
Simvastatin enhances bone morphogenetic protein receptor type II expression
-
16297860 1:CAS:528:DC%2BD2MXht1OrtrzL 10.1016/j.bbrc.2005.10.187
-
Hu H, Sung A, Zhao G, Shi L, Qiu D, Nishimura T, Kao PN (2006) Simvastatin enhances bone morphogenetic protein receptor type II expression. Biochem Biophys Res Commun 339:59-64
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 59-64
-
-
Hu, H.1
Sung, A.2
Zhao, G.3
Shi, L.4
Qiu, D.5
Nishimura, T.6
Kao, P.N.7
-
146
-
-
79958069658
-
The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension
-
21419223 1:CAS:528:DC%2BC3MXnt1Krs7g%3D 10.1016/j.phrs.2011.03.003
-
Shao D, Park JE, Wort SJ (2011) The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension. Pharmacol Res 63:504-511
-
(2011)
Pharmacol Res
, vol.63
, pp. 504-511
-
-
Shao, D.1
Park, J.E.2
Wort, S.J.3
-
147
-
-
0037158630
-
Acute and chronic hypoxic pulmonary vasoconstriction: A central role for endothelin-1?
-
12126698 1:CAS:528:DC%2BD38XntVKjtbY%3D 10.1016/S1569-9048(02)00052-6
-
Shimoda LA, Sham JS, Liu Q, Sylvester JT (2002) Acute and chronic hypoxic pulmonary vasoconstriction: a central role for endothelin-1? Respir Physiol Neurobiol 132:93-106
-
(2002)
Respir Physiol Neurobiol
, vol.132
, pp. 93-106
-
-
Shimoda, L.A.1
Sham, J.S.2
Liu, Q.3
Sylvester, J.T.4
-
149
-
-
68849115556
-
The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: Current understanding and future studies
-
1:CAS:528:DC%2BD1MXmvVyiur0%3D 10.1111/j.1365-2362.2009.02120.x
-
Davie NJ, Schermuly RT, Weissmann N, Grimminger F, Ghofrani HA (2009) The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: current understanding and future studies. Eur J Clin Investig 39(Suppl 2):38-49
-
(2009)
Eur J Clin Investig
, vol.39
, Issue.SUPPL. 2
, pp. 38-49
-
-
Davie, N.J.1
Schermuly, R.T.2
Weissmann, N.3
Grimminger, F.4
Ghofrani, H.A.5
-
150
-
-
53849083055
-
Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts
-
18695640 1:CAS:528:DC%2BD1cXht1emurvF 10.1038/bjp.2008.310
-
Mair KM, MacLean MR, Morecroft I, Dempsie Y, Palmer TM (2008) Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts. Br J Pharmacol 155:606-616
-
(2008)
Br J Pharmacol
, vol.155
, pp. 606-616
-
-
Mair, K.M.1
Maclean, M.R.2
Morecroft, I.3
Dempsie, Y.4
Palmer, T.M.5
-
151
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
1448077 1:CAS:528:DyaK3sXltFShsr0%3D
-
Semenza GL, Wang GL (1992) A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12:5447-5454
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
152
-
-
17644423994
-
Pulmonary vascular responses to chronic hypoxia mediated by hypoxia-inducible factor 1
-
16113471 1:CAS:528:DC%2BD28XhsFGitro%3D 10.1513/pats.200404-029MS
-
Semenza GL (2005) Pulmonary vascular responses to chronic hypoxia mediated by hypoxia-inducible factor 1. Proc Am Thorac Soc 2:68-70
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 68-70
-
-
Semenza, G.L.1
-
153
-
-
84864131464
-
Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2
-
22811423 1:CAS:528:DC%2BC38Xht1KmtbvF 10.1152/physrev.00030.2011
-
Prabhakar NR, Semenza GL (2012) Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2. Physiol Rev 92:967-1003
-
(2012)
Physiol Rev
, vol.92
, pp. 967-1003
-
-
Prabhakar, N.R.1
Semenza, G.L.2
-
154
-
-
0033104847
-
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
-
10074486 1:CAS:528:DyaK1MXhsF2is7o%3D 10.1172/JCI5912
-
Yu AY, Shimoda LA, Iyer NV, Huso DL, Sun X, McWilliams R, Beaty T, Sham JS, Wiener CM, Sylvester JT et al (1999) Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. J Clin Invest 103:691-696
-
(1999)
J Clin Invest
, vol.103
, pp. 691-696
-
-
Yu, A.Y.1
Shimoda, L.A.2
Iyer, N.V.3
Huso, D.L.4
Sun, X.5
McWilliams, R.6
Beaty, T.7
Sham, J.S.8
Wiener, C.M.9
Sylvester, J.T.10
-
155
-
-
78751690547
-
HIF and the lung: Role of hypoxia-inducible factors in pulmonary development and disease
-
21242594 1:CAS:528:DC%2BC3MXis1Cqsbo%3D 10.1164/rccm.201009-1393PP
-
Shimoda LA, Semenza GL (2011) HIF and the lung: role of hypoxia-inducible factors in pulmonary development and disease. Am J Respir Crit Care Med 183:152-156
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 152-156
-
-
Shimoda, L.A.1
Semenza, G.L.2
-
156
-
-
84875741389
-
55th Bowditch lecture: Effects of chronic hypoxia on the pulmonary circulation: Role of HIF-1
-
22923506 1:CAS:528:DC%2BC3sXhsVGjsQ%3D%3D 10.1152/japplphysiol.00843.2012
-
Shimoda LA (2012) 55th Bowditch lecture: effects of chronic hypoxia on the pulmonary circulation: role of HIF-1. J Appl Physiol 113:1343-1352
-
(2012)
J Appl Physiol
, vol.113
, pp. 1343-1352
-
-
Shimoda, L.A.1
-
157
-
-
15444342958
-
2 homeostasis by hypoxia-inducible factor 1α
-
9436976 1:CAS:528:DyaK1cXnsVOqsQ%3D%3D 10.1101/gad.12.2.149
-
2 homeostasis by hypoxia-inducible factor 1α. Genes Dev 12:149-162
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
-
158
-
-
85047691081
-
Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
-
12750401 1:CAS:528:DC%2BD3sXktVGisLs%3D
-
Brusselmans K, Compernolle V, Tjwa M, Wiesener MS, Maxwell PH, Collen D, Carmeliet P (2003) Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. J Clin Invest 111:1519-1527
-
(2003)
J Clin Invest
, vol.111
, pp. 1519-1527
-
-
Brusselmans, K.1
Compernolle, V.2
Tjwa, M.3
Wiesener, M.S.4
Maxwell, P.H.5
Collen, D.6
Carmeliet, P.7
-
159
-
-
77951216444
-
Hypoxic regulation of ion channels and transporters in pulmonary vascular smooth muscle
-
20204733 1:CAS:528:DC%2BC3cXhsFyjtr3L 10.1007/978-1-60761-500-2-14
-
Shimoda LA (2010) Hypoxic regulation of ion channels and transporters in pulmonary vascular smooth muscle. Adv Exp Med Biol 661:221-235
-
(2010)
Adv Exp Med Biol
, vol.661
, pp. 221-235
-
-
Shimoda, L.A.1
-
160
-
-
84856397577
-
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
-
22232678 1:CAS:528:DC%2BC38XislWksLw%3D 10.1073/pnas.1120385109
-
Abud EM, Maylor J, Undem C, Punjabi A, Zaiman AL, Myers AC, Sylvester JT, Semenza GL, Shimoda LA (2012) Digoxin inhibits development of hypoxic pulmonary hypertension in mice. Proc Natl Acad Sci U S A 109:1239-1244
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 1239-1244
-
-
Abud, E.M.1
Maylor, J.2
Undem, C.3
Punjabi, A.4
Zaiman, A.L.5
Myers, A.C.6
Sylvester, J.T.7
Semenza, G.L.8
Shimoda, L.A.9
|