메뉴 건너뛰기




Volumn 110, Issue 1, 2011, Pages 188-198

Effects of acute Rho kinase inhibition on chronic hypoxia-induced changes in proximal and distal pulmonary arterial structure and function

Author keywords

Arterial biomechanics; Impedance; Pulmonary circulation; Y27632

Indexed keywords

RHO KINASE;

EID: 79251509290     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00533.2010     Document Type: Article
Times cited : (42)

References (65)
  • 1
    • 0031110877 scopus 로고    scopus 로고
    • Hypoxia increases bromodeoxyuridine labeling indices in bovine neonatal pulmonary arteries
    • Belknap J, Orton E, Ensley B, Tucker A, Stenmark K. Hypoxia increases bromodeoxyuridine labeling indices in bovine neonatal pulmonary arteries. Am J Respir Cell Mol Biol 16: 366-371, 1997.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 366-371
    • Belknap, J.1    Orton, E.2    Ensley, B.3    Tucker, A.4    Stenmark, K.5
  • 2
    • 0021878915 scopus 로고
    • One-lung ventilation and hypoxic pulmonary vasoconstriction: Implications for anesthetic management
    • Benumof J. One-lung ventilation and hypoxic pulmonary vasoconstriction: implications for anesthetic management. Anesth Analg 64: 821-833, 1985.
    • (1985) Anesth Analg , vol.64 , pp. 821-833
    • Benumof, J.1
  • 4
    • 0024374262 scopus 로고
    • Pulmonary artery distensibility and blood flow patterns: A magnetic resonance study of normal subjects and of patients with pulmonary arterial hypertension
    • Bogren H, Klipstein R, Mohiaddin R, Firmin D, Underwood S, Rees R, Longmore D. Pulmonary artery distensibility and blood flow patterns: a magnetic resonance study of normal subjects and of patients with pulmonary arterial hypertension. Am Heart J 118: 990-999, 1989.
    • (1989) Am Heart J , vol.118 , pp. 990-999
    • Bogren, H.1    Klipstein, R.2    Mohiaddin, R.3    Firmin, D.4    Underwood, S.5    Rees, R.6    Longmore, D.7
  • 6
    • 70349776690 scopus 로고    scopus 로고
    • Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: State of the art and clinical and research implications
    • Champion H, Michelakis E, Hassoun P. Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications. Circulation 120: 992-1007, 2009.
    • (2009) Circulation , vol.120 , pp. 992-1007
    • Champion, H.1    Michelakis, E.2    Hassoun, P.3
  • 7
    • 59649110461 scopus 로고    scopus 로고
    • Vessel asymmetry as an additional diagnostic tool in the assessment of abdominal aortic aneurysms
    • Doyle B, Callanan A, Burke P, Grace P, Walsh M, Vorp D, Mc- Gloughlin T. Vessel asymmetry as an additional diagnostic tool in the assessment of abdominal aortic aneurysms. J Vasc Surg 49: 443-454, 2009.
    • (2009) J Vasc Surg , vol.49 , pp. 443-454
    • Doyle, B.1    Callanan, A.2    Burke, P.3    Grace, P.4    Walsh, M.5    Vorp, D.6    Mc- Gloughlin, T.7
  • 9
    • 68549132471 scopus 로고    scopus 로고
    • Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia
    • Estrada K, Chesler N. Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia. Biomech Model Mechanobiol 8: 263-272, 2009.
    • (2009) Biomech Model Mechanobiol , vol.8 , pp. 263-272
    • Estrada, K.1    Chesler, N.2
  • 10
    • 4544388803 scopus 로고    scopus 로고
    • Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase
    • Fagan K, Oka M, Bauer N, Gebb S, Ivy D, Morris K, McMurtry I. Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am J Physiol Lung Cell Mol Physiol 287: L656-L664, 2004.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287
    • Fagan, K.1    Oka, M.2    Bauer, N.3    Gebb, S.4    Ivy, D.5    Morris, K.6    McMurtry, I.7
  • 12
    • 0037899249 scopus 로고    scopus 로고
    • The myofibroblast in wound healing and fibrocontractive diseases
    • Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases. J Pathol 200: 500-503, 2003.
    • (2003) J Pathol , vol.200 , pp. 500-503
    • Gabbiani, G.1
  • 15
    • 0345829932 scopus 로고    scopus 로고
    • Extracellular ATP is an autocrine/paracrine regulator of hypoxiainduced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor
    • Gerasimovskaya E, Ahmad S, White C, Jones P, Carpenter T, Stenmark K. Extracellular ATP is an autocrine/paracrine regulator of hypoxiainduced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor. J Biol Chem 277: 44638-44650, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 44638-44650
    • Gerasimovskaya, E.1    Ahmad, S.2    White, C.3    Jones, P.4    Carpenter, T.5    Stenmark, K.6
  • 17
    • 0017099110 scopus 로고
    • New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension
    • Hislop A, Reid L. New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. Br J Exp Pathol 57: 542-554, 1976.
    • (1976) Br J Exp Pathol , vol.57 , pp. 542-554
    • Hislop, A.1    Reid, L.2
  • 19
    • 22744455284 scopus 로고    scopus 로고
    • Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation
    • Hyvelin JM, Howell K, Nichol A, Costello CM, Preston RJ, McLoughlin P. Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation. Circ Res 97: 185-191, 2005.
    • (2005) Circ Res , vol.97 , pp. 185-191
    • Hyvelin, J.M.1    Howell, K.2    Nichol, A.3    Costello, C.M.4    Preston, R.J.5    McLoughlin, P.6
  • 21
    • 31644431508 scopus 로고    scopus 로고
    • Beneficial acute effects of rho-kinase inhibitor in patients with pulmonary arterial hypertension
    • Ishikura K, Yamada N, Ito M, Ota S, Nakamura M, Isaka N, Nakano T. Beneficial acute effects of rho-kinase inhibitor in patients with pulmonary arterial hypertension. Circ J 70: 174-178, 2006.
    • (2006) Circ J , vol.70 , pp. 174-178
    • Ishikura, K.1    Yamada, N.2    Ito, M.3    Ota, S.4    Nakamura, M.5    Isaka, N.6    Nakano, T.7
  • 26
    • 33749325593 scopus 로고    scopus 로고
    • The mechanobiology of pulmonary vascular remodeling in the congenital absence of eNOS
    • Kobs RW, Chesler NC. The mechanobiology of pulmonary vascular remodeling in the congenital absence of eNOS. Biomech Model Mechanobiol 5: 217-225, 2006.
    • (2006) Biomech Model Mechanobiol , vol.5 , pp. 217-225
    • Kobs, R.W.1    Chesler, N.C.2
  • 27
    • 13944267913 scopus 로고    scopus 로고
    • Linked mechanical and biological aspects of remodeling in mouse pulmonary arteries with hypoxia-induced hypertension
    • Kobs RW, Muvarak NE, Eickhoff JC, Chesler NC. Linked mechanical and biological aspects of remodeling in mouse pulmonary arteries with hypoxia-induced hypertension. Am J Physiol Heart Circ Physiol 288: H1209-H1217, 2005.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Kobs, R.W.1    Muvarak, N.E.2    Eickhoff, J.C.3    Chesler, N.C.4
  • 29
    • 0023867096 scopus 로고
    • Multipoint pulmonary vascular pressure/flow relationships in hypoxic and in normoxic dogs: Effects of nitrous oxide with and without cyclooxygenase inhibition
    • Lejeune P, Deloof T, Leeman M, Mélot C, Naeije R. Multipoint pulmonary vascular pressure/flow relationships in hypoxic and in normoxic dogs: effects of nitrous oxide with and without cyclooxygenase inhibition. Anesthesiology 68: 92-99, 1988.
    • (1988) Anesthesiology , vol.68 , pp. 92-99
    • Lejeune, P.1    Deloof, T.2    Leeman, M.3    Mélot, C.4    Naeije, R.5
  • 30
    • 64249097973 scopus 로고    scopus 로고
    • Acute inhibition of Rho-kinase attenuates pulmonary hypertension in patients with congenital heart disease
    • Li F, Xia W, Yuan S, Sun R. Acute inhibition of Rho-kinase attenuates pulmonary hypertension in patients with congenital heart disease. Pediatr Cardiol 30: 363-366, 2009.
    • (2009) Pediatr Cardiol , vol.30 , pp. 363-366
    • Li, F.1    Xia, W.2    Yuan, S.3    Sun, R.4
  • 31
    • 0026744787 scopus 로고
    • A simple distensible vessel model for interpreting pulmonary vascular pressure-flow curves
    • Linehan J, Haworth S, Nelin L, Krenz G, Dawson C. A simple distensible vessel model for interpreting pulmonary vascular pressure-flow curves. J Appl Physiol 73: 987-994, 1992.
    • (1992) J Appl Physiol , vol.73 , pp. 987-994
    • Linehan, J.1    Haworth, S.2    Nelin, L.3    Krenz, G.4    Dawson, C.5
  • 32
    • 32644435423 scopus 로고    scopus 로고
    • Relationship of pulmonary arterial capacitance and mortality in idiopathic pulmonary arterial hypertension
    • DOI 10.1016/j.jacc.2005.09.054, PII S073510970502797X
    • Mahapatra S, Nishimura R, Sorajja P, Cha S, McGoon M. Relationship of pulmonary arterial capacitance and mortality in idiopathic pulmonary arterial hypertension. J Am Coll Cardiol 47: 799-803, 2006. (Pubitemid 43243104)
    • (2006) Journal of the American College of Cardiology , vol.47 , Issue.4 , pp. 799-803
    • Mahapatra, S.1    Nishimura, R.A.2    Sorajja, P.3    Cha, S.4    McGoon, M.D.5
  • 33
    • 0017325963 scopus 로고
    • General anesthetics and regional hypoxic pulmonary vasoconstriction
    • Mathers J, Benumof J, Wahrenbrock E. General anesthetics and regional hypoxic pulmonary vasoconstriction. Anesthesiology 46: 111-114, 1977. (Pubitemid 8035218)
    • (1977) Anesthesiology , vol.46 , Issue.2 , pp. 111-114
    • Mathers, J.1    Benumof, J.L.2    Wahrenbrock, E.A.3
  • 34
    • 64849109410 scopus 로고    scopus 로고
    • ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society,; And the Pulmonary Hypertension Association
    • McLaughlin V, Archer S, Badesch D, Barst R, Farber H, Lindner J, Mathier M, McGoon M, Park M, Rosenson R, Rubin L, Tapson V, Varga J. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society,; and the Pulmonary Hypertension Association. J Am Coll Cardiol 53: 1573-1619, 2009.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1573-1619
    • McLaughlin, V.1    Archer, S.2    Badesch, D.3    Barst, R.4    Farber, H.5    Lindner, J.6    Mathier, M.7    McGoon, M.8    Park, M.9    Rosenson, R.10    Rubin, L.11    Tapson, V.12    Varga, J.13
  • 35
    • 77951239891 scopus 로고    scopus 로고
    • Rho kinase-mediated vasoconstriction in pulmonary hypertension
    • McMurtry I, Abe K, Ota H, Fagan K, Oka M. Rho kinase-mediated vasoconstriction in pulmonary hypertension. Adv Exp Med Biol 661: 299-308, 2010.
    • (2010) Adv Exp Med Biol , vol.661 , pp. 299-308
    • McMurtry, I.1    Abe, K.2    Ota, H.3    Fagan, K.4    Oka, M.5
  • 37
    • 0020570619 scopus 로고
    • Pulmonary hypertension. Anatomic and physiologic correlates
    • Meyrick B, Reid L. Pulmonary hypertension. Anatomic and physiologic correlates. Clin Chest Med 4: 199-217, 1983.
    • (1983) Clin Chest Med , vol.4 , pp. 199-217
    • Meyrick, B.1    Reid, L.2
  • 38
    • 0004045209 scopus 로고
    • Baltimore, MD: Williams and Wilkins
    • Milnor WR. Hemodynamics. Baltimore, MD: Williams and Wilkins, 1989, p. 419.
    • (1989) Hemodynamics , pp. 419
    • Milnor, W.R.1
  • 39
    • 9244236573 scopus 로고    scopus 로고
    • Quantitative models of the rat pulmonary arterial tree morphometry applied to hypoxia-induced arterial remodeling
    • Molthen RC, Karau KL, Dawson CA. Quantitative models of the rat pulmonary arterial tree morphometry applied to hypoxia-induced arterial remodeling. J Appl Physiol 97: 2372-2384, 2004.
    • (2004) J Appl Physiol , vol.97 , pp. 2372-2384
    • Molthen, R.C.1    Karau, K.L.2    Dawson, C.A.3
  • 40
    • 34548820973 scopus 로고    scopus 로고
    • P38 MAP kinase: Essential role in hypoxia-mediated human pulmonary artery fibroblast proliferation
    • Mortimer H, Peacock A, Kirk A, Welsh D. p38 MAP kinase: essential role in hypoxia-mediated human pulmonary artery fibroblast proliferation. Pulm Pharmacol Ther 20: 718-725, 2007.
    • (2007) Pulm Pharmacol Ther , vol.20 , pp. 718-725
    • Mortimer, H.1    Peacock, A.2    Kirk, A.3    Welsh, D.4
  • 41
    • 25644449318 scopus 로고    scopus 로고
    • Pulmonary vascular function
    • edited by Peacock AJ and Rubin LJ. London: Arnold
    • Naeije R. Pulmonary vascular function. In: Pulmonary Circulation: Diseases and Their Treatment, edited by Peacock AJ and Rubin LJ. London: Arnold, 2004, p. 3-11.
    • (2004) Pulmonary Circulation: Diseases and Their Treatment , pp. 3-11
    • Naeije, R.1
  • 45
    • 77952009600 scopus 로고    scopus 로고
    • Geometric variability of the abdominal aorta and its major peripheral branches
    • O'Flynn P, O'Sullivan G, Pandit A. Geometric variability of the abdominal aorta and its major peripheral branches. Ann Biomed Eng 38: 824-840, 2010.
    • (2010) Ann Biomed Eng , vol.38 , pp. 824-840
    • O'flynn, P.1    O'sullivan, G.2    Pandit, A.3
  • 47
    • 0036933489 scopus 로고    scopus 로고
    • The myofibroblast in pulmonary fibrosis
    • Phan S. The myofibroblast in pulmonary fibrosis. Chest 122: 286S-289S, 2002.
    • (2002) Chest , vol.122
    • Phan, S.1
  • 49
    • 0023234321 scopus 로고
    • Inhibition of vasoactive agents by perfluorochemical emulsion
    • Saeed M, Hartmann A, Bing R. Inhibition of vasoactive agents by perfluorochemical emulsion. Life Sci 40: 1971-1979, 1987.
    • (1971) Life Sci , vol.40 , pp. 1987
    • Saeed, M.1    Hartmann, A.2    Bing, R.3
  • 51
    • 38349045165 scopus 로고    scopus 로고
    • Changes in macrovessel pulmonary blood flow distribution following chronic hypoxia: Assessed using synchrotron radiation microangiography
    • Schwenke D, Pearson J, Kangawa K, Umetani K, Shirai M. Changes in macrovessel pulmonary blood flow distribution following chronic hypoxia: assessed using synchrotron radiation microangiography. J Appl Physiol 104: 88-96, 2008.
    • (2008) J Appl Physiol , vol.104 , pp. 88-96
    • Schwenke, D.1    Pearson, J.2    Kangawa, K.3    Umetani, K.4    Shirai, M.5
  • 52
    • 33846880481 scopus 로고    scopus 로고
    • Imaging of the pulmonary circulation in the closed-chest rat using synchrotron radiation microangiography
    • Schwenke D, Pearson J, Umetani K, Kangawa K, Shirai M. Imaging of the pulmonary circulation in the closed-chest rat using synchrotron radiation microangiography. J Appl Physiol 102: 787-793, 2007.
    • (2007) J Appl Physiol , vol.102 , pp. 787-793
    • Schwenke, D.1    Pearson, J.2    Umetani, K.3    Kangawa, K.4    Shirai, M.5
  • 53
    • 71949129187 scopus 로고    scopus 로고
    • Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
    • Stenmark K, Meyrick B, Galie N, Mooi W, McMurtry I. Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol 297: L1013-L1032, 2009.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297
    • Stenmark, K.1    Meyrick, B.2    Galie, N.3    Mooi, W.4    McMurtry, I.5
  • 54
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
    • Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 99: 675-691, 2006.
    • (2006) Circ Res , vol.99 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 55
    • 22744457972 scopus 로고    scopus 로고
    • Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: A time for reappraisal?
    • Stenmark KR, McMurtry IF. Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal? Circ Res 97: 95-98, 2005.
    • (2005) Circ Res , vol.97 , pp. 95-98
    • Stenmark, K.R.1    McMurtry, I.F.2
  • 56
    • 77954142754 scopus 로고    scopus 로고
    • The effects of vasoactivity and hypoxic pulmonary hypertension on extralobar pulmonary artery biomechanics
    • Tabima D, Chesler N. The effects of vasoactivity and hypoxic pulmonary hypertension on extralobar pulmonary artery biomechanics. J Biomech 43: 1864-1869, 2010.
    • (2010) J Biomech , vol.43 , pp. 1864-1869
    • Tabima, D.1    Chesler, N.2
  • 58
    • 33847675337 scopus 로고    scopus 로고
    • Pulmonary vascular remodeling in isolated mouse lungs: Effects on pulsatile pressure-flow relationships
    • Tuchscherer HA, Vanderpool RR, Chesler NC. Pulmonary vascular remodeling in isolated mouse lungs: effects on pulsatile pressure-flow relationships. J Biomech 40: 993-1001, 2007.
    • (2007) J Biomech , vol.40 , pp. 993-1001
    • Tuchscherer, H.A.1    Vanderpool, R.R.2    Chesler, N.C.3
  • 59
    • 33645968995 scopus 로고    scopus 로고
    • Pulmonary vascular resistance and impedance in isolated mouse lungs: Effects of pulmonary emboli
    • Tuchscherer HA, Webster EB, Chesler NC. Pulmonary vascular resistance and impedance in isolated mouse lungs: effects of pulmonary emboli. Ann Biomed Eng 34: 660-668, 2006.
    • (2006) Ann Biomed Eng , vol.34 , pp. 660-668
    • Tuchscherer, H.A.1    Webster, E.B.2    Chesler, N.C.3
  • 60
    • 77952011655 scopus 로고    scopus 로고
    • Impedance in isolated mouse lungs for the determination of site of action of vasoactive agents and disease
    • Vanderpool RR, Naeije R, Chesler NC. Impedance in isolated mouse lungs for the determination of site of action of vasoactive agents and disease. Ann Biomed Eng 38: 1854-1861, 2010.
    • (2010) Ann Biomed Eng , vol.38 , pp. 1854-1861
    • Vanderpool, R.R.1    Naeije, R.2    Chesler, N.C.3
  • 65
    • 0036081679 scopus 로고    scopus 로고
    • Regional arterial stress-strain distributions referenced to the zero-stress state in the rat
    • Zhao J, Day J, Yuan Z, Gregersen H. Regional arterial stress-strain distributions referenced to the zero-stress state in the rat. Am J Physiol Heart Circ Physiol 282: H622-H629, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Zhao, J.1    Day, J.2    Yuan, Z.3    Gregersen, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.