-
1
-
-
0024256133
-
Novel regulators of bone formation: molecular clones and activities
-
Wozney J.M., Rosen V., Celeste A.J., Mitsock L.M., Whitters M.J., Kriz R.W., et al. Novel regulators of bone formation: molecular clones and activities. Science 1988, 242:1528-1534.
-
(1988)
Science
, vol.242
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.W.6
-
3
-
-
0037250476
-
Consequences of knocking out BMP signaling in the mouse
-
Zhao G.Q. Consequences of knocking out BMP signaling in the mouse. Genesis 2003, 35:43-56.
-
(2003)
Genesis
, vol.35
, pp. 43-56
-
-
Zhao, G.Q.1
-
4
-
-
35748943880
-
Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development
-
Andersson O., Bertolino P., Ibanez C.F. Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development. Dev Biol 2007, 311:500-511.
-
(2007)
Dev Biol
, vol.311
, pp. 500-511
-
-
Andersson, O.1
Bertolino, P.2
Ibanez, C.F.3
-
5
-
-
33747762981
-
Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis
-
Andersson O., Reissmann E., Ibanez C.F. Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis. EMBO Rep 2006, 7:831-837.
-
(2006)
EMBO Rep
, vol.7
, pp. 831-837
-
-
Andersson, O.1
Reissmann, E.2
Ibanez, C.F.3
-
6
-
-
0141864365
-
Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis
-
Rebbapragada A., Benchabane H., Wrana J.L., Celeste A.J., Attisano L. Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis. Mol Cell Biol 2003, 23:7230-7242.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7230-7242
-
-
Rebbapragada, A.1
Benchabane, H.2
Wrana, J.L.3
Celeste, A.J.4
Attisano, L.5
-
7
-
-
24144438593
-
BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos
-
Gamer L.W., Nove J., Levin M., Rosen V. BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos. Dev Biol 2005, 285:156-168.
-
(2005)
Dev Biol
, vol.285
, pp. 156-168
-
-
Gamer, L.W.1
Nove, J.2
Levin, M.3
Rosen, V.4
-
8
-
-
0037424231
-
Inhibin is an antagonist of bone morphogenetic protein signaling
-
Wiater E., Vale W. Inhibin is an antagonist of bone morphogenetic protein signaling. J Biol Chem 2003, 278:7934-7941.
-
(2003)
J Biol Chem
, vol.278
, pp. 7934-7941
-
-
Wiater, E.1
Vale, W.2
-
9
-
-
70649101154
-
Control of BMP gene expression by long-range regulatory elements
-
Pregizer S., Mortlock D.P. Control of BMP gene expression by long-range regulatory elements. Cytokine Growth Factor Rev 2009, 20:509-515.
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, pp. 509-515
-
-
Pregizer, S.1
Mortlock, D.P.2
-
10
-
-
0032541405
-
BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development
-
Cui Y., Jean F., Thomas G., Christian J.L. BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development. EMBO J 1998, 17:4735-4743.
-
(1998)
EMBO J
, vol.17
, pp. 4735-4743
-
-
Cui, Y.1
Jean, F.2
Thomas, G.3
Christian, J.L.4
-
11
-
-
0033545215
-
Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases
-
Constam D.B., Robertson E.J. Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. J Cell Biol 1999, 144:139-149.
-
(1999)
J Cell Biol
, vol.144
, pp. 139-149
-
-
Constam, D.B.1
Robertson, E.J.2
-
12
-
-
33745094372
-
Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity
-
Goldman D.C., Hackenmiller R., Nakayama T., Sopory S., Wong C., Kulessa H., et al. Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity. Development 2006, 133:1933-1942.
-
(2006)
Development
, vol.133
, pp. 1933-1942
-
-
Goldman, D.C.1
Hackenmiller, R.2
Nakayama, T.3
Sopory, S.4
Wong, C.5
Kulessa, H.6
-
13
-
-
23044515502
-
The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix
-
Gregory K.E., Ono R.N., Charbonneau N.L., Kuo C.L., Keene D.R., Bachinger H.P., et al. The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix. J Biol Chem 2005, 280:27970-27980.
-
(2005)
J Biol Chem
, vol.280
, pp. 27970-27980
-
-
Gregory, K.E.1
Ono, R.N.2
Charbonneau, N.L.3
Kuo, C.L.4
Keene, D.R.5
Bachinger, H.P.6
-
14
-
-
21644461778
-
Crystal structure of BMP-9 and functional interactions with pro-region and receptors
-
Brown M.A., Zhao Q., Baker K.A., Naik C., Chen C., Pukac L., et al. Crystal structure of BMP-9 and functional interactions with pro-region and receptors. J Biol Chem 2005, 280:25111-25118.
-
(2005)
J Biol Chem
, vol.280
, pp. 25111-25118
-
-
Brown, M.A.1
Zhao, Q.2
Baker, K.A.3
Naik, C.4
Chen, C.5
Pukac, L.6
-
15
-
-
70450170394
-
The extracellular regulation of bone morphogenetic protein signaling
-
Umulis D., O'Connor M.B., Blair S.S. The extracellular regulation of bone morphogenetic protein signaling. Development 2009, 136:3715-3728.
-
(2009)
Development
, vol.136
, pp. 3715-3728
-
-
Umulis, D.1
O'Connor, M.B.2
Blair, S.S.3
-
16
-
-
73649136476
-
Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN
-
Seemann P., Brehm A., Konig J., Reissner C., Stricker S., Kuss P., et al. Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN. PLoS Genet 2009, 5(11):e1000747.
-
(2009)
PLoS Genet
, vol.5
, Issue.11
-
-
Seemann, P.1
Brehm, A.2
Konig, J.3
Reissner, C.4
Stricker, S.5
Kuss, P.6
-
17
-
-
0030598829
-
The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
-
Zimmerman L.B., De Jesus-Escobar J.M., Harland R.M. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 1996, 86:599-606.
-
(1996)
Cell
, vol.86
, pp. 599-606
-
-
Zimmerman, L.B.1
De Jesus-Escobar, J.M.2
Harland, R.M.3
-
18
-
-
0030598867
-
Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4
-
Piccolo S., Sasai Y., Lu B., De Robertis E.M. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 1996, 86:589-598.
-
(1996)
Cell
, vol.86
, pp. 589-598
-
-
Piccolo, S.1
Sasai, Y.2
Lu, B.3
De Robertis, E.M.4
-
19
-
-
0035205079
-
Proteolytic cleavage of chordin as a switch for the dual activities of twisted gastrulation in BMP signaling
-
Larrain J., Oelgeschlager M., Ketpura N.I., Reversade B., Zakin L., De Robertis E.M. Proteolytic cleavage of chordin as a switch for the dual activities of twisted gastrulation in BMP signaling. Development 2001, 128:4439-4447.
-
(2001)
Development
, vol.128
, pp. 4439-4447
-
-
Larrain, J.1
Oelgeschlager, M.2
Ketpura, N.I.3
Reversade, B.4
Zakin, L.5
De Robertis, E.M.6
-
20
-
-
75649127963
-
Bone morphogenetic protein receptors and signal transduction
-
Miyazono K., Kamiya Y., Morikawa M. Bone morphogenetic protein receptors and signal transduction. J Biochem 2010, 147:35-51.
-
(2010)
J Biochem
, vol.147
, pp. 35-51
-
-
Miyazono, K.1
Kamiya, Y.2
Morikawa, M.3
-
21
-
-
70450187617
-
The regulation of TGFbeta signal transduction
-
Moustakas A., Heldin C.H. The regulation of TGFbeta signal transduction. Development 2009, 136:3699-3714.
-
(2009)
Development
, vol.136
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.H.2
-
22
-
-
34547882714
-
A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor
-
Chan M.C., Nguyen P.H., Davis B.N., Ohoka N., Hayashi H., Du K., et al. A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor. Mol Cell Biol 2007, 27:5776-5789.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5776-5789
-
-
Chan, M.C.1
Nguyen, P.H.2
Davis, B.N.3
Ohoka, N.4
Hayashi, H.5
Du, K.6
-
23
-
-
67349167022
-
Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity
-
Schwappacher R., Weiske J., Heining E., Ezerski V., Marom B., Henis Y.I., et al. Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity. EMBO J 2009, 28:1537-1550.
-
(2009)
EMBO J
, vol.28
, pp. 1537-1550
-
-
Schwappacher, R.1
Weiske, J.2
Heining, E.3
Ezerski, V.4
Marom, B.5
Henis, Y.I.6
-
24
-
-
11244313831
-
Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis
-
Lee-Hoeflich S.T., Causing C.G., Podkowa M., Zhao X., Wrana J.L., Attisano L. Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis. EMBO J 2004, 23:4792-4801.
-
(2004)
EMBO J
, vol.23
, pp. 4792-4801
-
-
Lee-Hoeflich, S.T.1
Causing, C.G.2
Podkowa, M.3
Zhao, X.4
Wrana, J.L.5
Attisano, L.6
-
25
-
-
70649098149
-
Intricacies of BMP receptor assembly
-
Nickel J., Sebald W., Groppe J.C., Mueller T.D. Intricacies of BMP receptor assembly. Cytokine Growth Factor Rev 2009, 20:367-377.
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, pp. 367-377
-
-
Nickel, J.1
Sebald, W.2
Groppe, J.C.3
Mueller, T.D.4
-
26
-
-
0025323376
-
Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily
-
Sampath T.K., Coughlin J.E., Whetstone R.M., Banach D., Corbett C., Ridge R.J., et al. Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily. J Biol Chem 1990, 265:13198-13205.
-
(1990)
J Biol Chem
, vol.265
, pp. 13198-13205
-
-
Sampath, T.K.1
Coughlin, J.E.2
Whetstone, R.M.3
Banach, D.4
Corbett, C.5
Ridge, R.J.6
-
27
-
-
0029028648
-
Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system
-
Hazama M., Aono A., Ueno N., Fujisawa Y. Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system. Biochem Biophys Res Commun 1995, 209:859-866.
-
(1995)
Biochem Biophys Res Commun
, vol.209
, pp. 859-866
-
-
Hazama, M.1
Aono, A.2
Ueno, N.3
Fujisawa, Y.4
-
28
-
-
67349187409
-
Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis
-
Little S.C., Mullins M.C. Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat Cell Biol 2009, 11:637-643.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 637-643
-
-
Little, S.C.1
Mullins, M.C.2
-
29
-
-
1542357571
-
Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5
-
Mazerbourg S., Klein C., Roh J., Kaivo-Oja N., Mottershead D.G., Korchynskyi O., et al. Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5. Mol Endocrinol 2004, 18:653-665.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 653-665
-
-
Mazerbourg, S.1
Klein, C.2
Roh, J.3
Kaivo-Oja, N.4
Mottershead, D.G.5
Korchynskyi, O.6
-
30
-
-
0035992835
-
Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9
-
Vitt U.A., Mazerbourg S., Klein C., Hsueh A.J. Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9. Biol Reprod 2002, 67:473-480.
-
(2002)
Biol Reprod
, vol.67
, pp. 473-480
-
-
Vitt, U.A.1
Mazerbourg, S.2
Klein, C.3
Hsueh, A.J.4
-
31
-
-
55849145475
-
Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth
-
Daly A.C., Randall R.A., Hill C.S. Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth. Mol Cell Biol 2008, 28:6889-6902.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6889-6902
-
-
Daly, A.C.1
Randall, R.A.2
Hill, C.S.3
-
32
-
-
0242330126
-
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
-
Goumans M.J., Valdimarsdottir G., Itoh S., Lebrin F., Larsson J., Mummery C., et al. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Mol Cell 2003, 12:817-828.
-
(2003)
Mol Cell
, vol.12
, pp. 817-828
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
Lebrin, F.4
Larsson, J.5
Mummery, C.6
-
33
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
-
Goumans M.J., Valdimarsdottir G., Itoh S., Rosendahl A., Sideras P., ten Dijke P. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J 2002, 21:1743-1753.
-
(2002)
EMBO J
, vol.21
, pp. 1743-1753
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
Rosendahl, A.4
Sideras, P.5
ten Dijke, P.6
-
34
-
-
0032990886
-
Functional antagonism between activin and osteogenic protein-1 in human embryonal carcinoma cells
-
Piek E., Afrakhte M., Sampath K., van Zoelen E.J., Heldin C.H., ten Dijke P. Functional antagonism between activin and osteogenic protein-1 in human embryonal carcinoma cells. J Cell Physiol 1999, 180:141-149.
-
(1999)
J Cell Physiol
, vol.180
, pp. 141-149
-
-
Piek, E.1
Afrakhte, M.2
Sampath, K.3
van Zoelen, E.J.4
Heldin, C.H.5
ten Dijke, P.6
-
35
-
-
27544501019
-
Cell-surface co-receptors: emerging roles in signaling and human disease
-
Kirkbride K.C., Ray B.N., Blobe G.C. Cell-surface co-receptors: emerging roles in signaling and human disease. Trends Biochem Sci 2005, 30:611-621.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 611-621
-
-
Kirkbride, K.C.1
Ray, B.N.2
Blobe, G.C.3
-
36
-
-
0027976511
-
Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites
-
Lopez-Casillas F., Payne H.M., Andres J.L., Massague J. Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites. J Cell Biol 1994, 124:557-568.
-
(1994)
J Cell Biol
, vol.124
, pp. 557-568
-
-
Lopez-Casillas, F.1
Payne, H.M.2
Andres, J.L.3
Massague, J.4
-
37
-
-
33744985816
-
Soluble endoglin contributes to the pathogenesis of preeclampsia
-
Venkatesha S., Toporsian M., Lam C., Hanai J., Mammoto T., Kim Y.M., et al. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med 2006, 12:642-649.
-
(2006)
Nat Med
, vol.12
, pp. 642-649
-
-
Venkatesha, S.1
Toporsian, M.2
Lam, C.3
Hanai, J.4
Mammoto, T.5
Kim, Y.M.6
-
38
-
-
43149095145
-
Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptor
-
Kirkbride K.C., Townsend T.A., Bruinsma M.W., Barnett J.V., Blobe G.C. Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptor. J Biol Chem 2008, 283:7628-7637.
-
(2008)
J Biol Chem
, vol.283
, pp. 7628-7637
-
-
Kirkbride, K.C.1
Townsend, T.A.2
Bruinsma, M.W.3
Barnett, J.V.4
Blobe, G.C.5
-
39
-
-
0034704753
-
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
-
Lewis K.A., Gray P.C., Blount A.L., MacConell L.A., Wiater E., Bilezikjian L.M., et al. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature 2000, 404:411-414.
-
(2000)
Nature
, vol.404
, pp. 411-414
-
-
Lewis, K.A.1
Gray, P.C.2
Blount, A.L.3
MacConell, L.A.4
Wiater, E.5
Bilezikjian, L.M.6
-
40
-
-
43149095145
-
Bone morphogenetic proteins signal through the transforming growth factor-β type III receptor
-
Kirkbride K.C., Townsend T.A., Bruinsma M.W., Barnett J.V., Blobe G.C. Bone morphogenetic proteins signal through the transforming growth factor-β type III receptor. J Biol Chem 2008, 283:7628-7637.
-
(2008)
J Biol Chem
, vol.283
, pp. 7628-7637
-
-
Kirkbride, K.C.1
Townsend, T.A.2
Bruinsma, M.W.3
Barnett, J.V.4
Blobe, G.C.5
-
41
-
-
70350088248
-
The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors
-
Lee N.Y., Kirkbride K.C., Sheu R.D., Blobe G.C. The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors. Mol Biol Cell 2009, 20:4362-4370.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 4362-4370
-
-
Lee, N.Y.1
Kirkbride, K.C.2
Sheu, R.D.3
Blobe, G.C.4
-
42
-
-
0033534572
-
Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-β superfamily
-
Barbara N.P., Wrana J.L., Letarte M. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-β superfamily. J Biol Chem 1999, 274:584-594.
-
(1999)
J Biol Chem
, vol.274
, pp. 584-594
-
-
Barbara, N.P.1
Wrana, J.L.2
Letarte, M.3
-
43
-
-
34247331476
-
BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis
-
Scharpfenecker M., van Dinther M., Liu Z., van Bezooijen R.L., Zhao Q., Pukac L., et al. BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis. J Cell Sci 2007, 120:964-972.
-
(2007)
J Cell Sci
, vol.120
, pp. 964-972
-
-
Scharpfenecker, M.1
van Dinther, M.2
Liu, Z.3
van Bezooijen, R.L.4
Zhao, Q.5
Pukac, L.6
-
44
-
-
33847369980
-
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
-
David L., Mallet C., Mazerbourg S., Feige J.J., Bailly S. Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 2007, 109:1953-1961.
-
(2007)
Blood
, vol.109
, pp. 1953-1961
-
-
David, L.1
Mallet, C.2
Mazerbourg, S.3
Feige, J.J.4
Bailly, S.5
-
45
-
-
34347230515
-
Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling
-
Scherner O., Meurer S.K., Tihaa L., Gressner A.M., Weiskirchen R. Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling. J Biol Chem 2007, 282:13934-13943.
-
(2007)
J Biol Chem
, vol.282
, pp. 13934-13943
-
-
Scherner, O.1
Meurer, S.K.2
Tihaa, L.3
Gressner, A.M.4
Weiskirchen, R.5
-
46
-
-
0033534572
-
Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily
-
Barbara N.P., Wrana J.L., Letarte M. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J Biol Chem 1999, 274:584-594.
-
(1999)
J Biol Chem
, vol.274
, pp. 584-594
-
-
Barbara, N.P.1
Wrana, J.L.2
Letarte, M.3
-
47
-
-
77950880642
-
ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration
-
Ray B.N., Lee N.Y., How T., Blobe G.C. ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration. Carcinogenesis 2009, 31(3):435-441.
-
(2009)
Carcinogenesis
, vol.31
, Issue.3
, pp. 435-441
-
-
Ray, B.N.1
Lee, N.Y.2
How, T.3
Blobe, G.C.4
-
48
-
-
39049121312
-
How the Smads regulate transcription
-
Ross S., Hill C.S. How the Smads regulate transcription. Int J Biochem Cell Biol 2008, 40:383-408.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 383-408
-
-
Ross, S.1
Hill, C.S.2
-
49
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y., Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003, 113:685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
50
-
-
65649105437
-
Transforming growth factor {beta} can stimulate smad1 phosphorylation independently of bone morphogenic protein receptors
-
Wrighton K.H., Lin X., Yu P.B., Feng X.H. Transforming growth factor {beta} can stimulate smad1 phosphorylation independently of bone morphogenic protein receptors. J Biol Chem 2009, 284:9755-9763.
-
(2009)
J Biol Chem
, vol.284
, pp. 9755-9763
-
-
Wrighton, K.H.1
Lin, X.2
Yu, P.B.3
Feng, X.H.4
-
51
-
-
58749089988
-
TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch
-
Liu I.M., Schilling S.H., Knouse K.A., Choy L., Derynck R., Wang X.F. TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch. EMBO J 2009, 28:88-98.
-
(2009)
EMBO J
, vol.28
, pp. 88-98
-
-
Liu, I.M.1
Schilling, S.H.2
Knouse, K.A.3
Choy, L.4
Derynck, R.5
Wang, X.F.6
-
52
-
-
73349089657
-
Endoglin is involved in BMP-2-induced osteogenic differentiation of periodontal ligament cells through a pathway independent of Smad-1/5/8 phosphorylation
-
Ishibashi O., Ikegame M., Takizawa F., Yoshizawa T., Moksed M.A., Iizawa F., et al. Endoglin is involved in BMP-2-induced osteogenic differentiation of periodontal ligament cells through a pathway independent of Smad-1/5/8 phosphorylation. J Cell Physiol 2010, 222:465-473.
-
(2010)
J Cell Physiol
, vol.222
, pp. 465-473
-
-
Ishibashi, O.1
Ikegame, M.2
Takizawa, F.3
Yoshizawa, T.4
Moksed, M.A.5
Iizawa, F.6
-
53
-
-
67650188576
-
Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells
-
Upton P.D., Davies R.J., Trembath R.C., Morrell N.W. Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells. J Biol Chem 2009, 284:15794-15804.
-
(2009)
J Biol Chem
, vol.284
, pp. 15794-15804
-
-
Upton, P.D.1
Davies, R.J.2
Trembath, R.C.3
Morrell, N.W.4
-
54
-
-
58149218252
-
Regulating the stability of TGFbeta receptors and Smads
-
Lonn P., Moren A., Raja E., Dahl M., Moustakas A. Regulating the stability of TGFbeta receptors and Smads. Cell Res 2009, 19:21-35.
-
(2009)
Cell Res
, vol.19
, pp. 21-35
-
-
Lonn, P.1
Moren, A.2
Raja, E.3
Dahl, M.4
Moustakas, A.5
-
55
-
-
58149239730
-
Phospho-control of TGF-beta superfamily signaling
-
Wrighton K.H., Lin X., Feng X.H. Phospho-control of TGF-beta superfamily signaling. Cell Res 2009, 19:8-20.
-
(2009)
Cell Res
, vol.19
, pp. 8-20
-
-
Wrighton, K.H.1
Lin, X.2
Feng, X.H.3
-
56
-
-
0036829567
-
Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase
-
Funaba M., Zimmerman C.M., Mathews L.S. Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase. J Biol Chem 2002, 277:41361-41368.
-
(2002)
J Biol Chem
, vol.277
, pp. 41361-41368
-
-
Funaba, M.1
Zimmerman, C.M.2
Mathews, L.S.3
-
57
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
de Caestecker M.P., Parks W.T., Frank C.J., Castagnino P., Bottaro D.P., Roberts A.B., et al. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev 1998, 12:1587-1592.
-
(1998)
Genes Dev
, vol.12
, pp. 1587-1592
-
-
de Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
Castagnino, P.4
Bottaro, D.P.5
Roberts, A.B.6
-
58
-
-
68549098152
-
Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells
-
Liu Y., Ren W., Warburton R., Toksoz D., Fanburg B.L. Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells. FASEB J 2009, 23:2299-2306.
-
(2009)
FASEB J
, vol.23
, pp. 2299-2306
-
-
Liu, Y.1
Ren, W.2
Warburton, R.3
Toksoz, D.4
Fanburg, B.L.5
-
59
-
-
1542569747
-
Smad4 and beta-catenin co-activators functionally interact with lymphoid-enhancing factor to regulate graded expression of Msx2
-
Hussein S.M., Duff E.K., Sirard C. Smad4 and beta-catenin co-activators functionally interact with lymphoid-enhancing factor to regulate graded expression of Msx2. J Biol Chem 2003, 278:48805-48814.
-
(2003)
J Biol Chem
, vol.278
, pp. 48805-48814
-
-
Hussein, S.M.1
Duff, E.K.2
Sirard, C.3
-
60
-
-
10744231139
-
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells
-
Itoh F., Itoh S., Goumans M.J., Valdimarsdottir G., Iso T., Dotto G.P., et al. Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. EMBO J 2004, 23:541-551.
-
(2004)
EMBO J
, vol.23
, pp. 541-551
-
-
Itoh, F.1
Itoh, S.2
Goumans, M.J.3
Valdimarsdottir, G.4
Iso, T.5
Dotto, G.P.6
-
61
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
Davis B.N., Hilyard A.C., Lagna G., Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008, 454:56-61.
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
62
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D., Villen J., Shin C., Camargo F.D., Gygi S.P., Bartel D.P. The impact of microRNAs on protein output. Nature 2008, 455:64-71.
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
63
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach M., Schwanhausser B., Thierfelder N., Fang Z., Khanin R., Rajewsky N. Widespread changes in protein synthesis induced by microRNAs. Nature 2008, 455:58-63.
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
64
-
-
76349093390
-
Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression
-
Chan M.C., Hilyard A.C., Wu C., Davis B.N., Hill N.S., Lal A., et al. Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J 2010, 29(3):559-573.
-
(2010)
EMBO J
, vol.29
, Issue.3
, pp. 559-573
-
-
Chan, M.C.1
Hilyard, A.C.2
Wu, C.3
Davis, B.N.4
Hill, N.S.5
Lal, A.6
-
65
-
-
58149213801
-
Non-Smad pathways in TGF-beta signaling
-
Zhang Y.E. Non-Smad pathways in TGF-beta signaling. Cell Res 2009, 19:128-139.
-
(2009)
Cell Res
, vol.19
, pp. 128-139
-
-
Zhang, Y.E.1
-
66
-
-
0034021776
-
Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors
-
Gilboa L., Nohe A., Geissendorfer T., Sebald W., Henis Y.I., Knaus P. Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Mol Biol Cell 2000, 11:1023-1035.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 1023-1035
-
-
Gilboa, L.1
Nohe, A.2
Geissendorfer, T.3
Sebald, W.4
Henis, Y.I.5
Knaus, P.6
-
67
-
-
0041633633
-
Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes
-
A
-
Hassel S., Schmitt S., Hartung A., Roth M., Nohe A., Petersen N., et al. Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes. J Bone Joint Surg Am 2003, 85A(Suppl. 3):44-51.
-
(2003)
J Bone Joint Surg Am
, vol.85
, Issue.SUPPL. 3
, pp. 44-51
-
-
Hassel, S.1
Schmitt, S.2
Hartung, A.3
Roth, M.4
Nohe, A.5
Petersen, N.6
-
68
-
-
0037085287
-
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
-
Nohe A., Hassel S., Ehrlich M., Neubauer F., Sebald W., Henis Y.I., et al. The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J Biol Chem 2002, 277:5330-5338.
-
(2002)
J Biol Chem
, vol.277
, pp. 5330-5338
-
-
Nohe, A.1
Hassel, S.2
Ehrlich, M.3
Neubauer, F.4
Sebald, W.5
Henis, Y.I.6
-
69
-
-
0033521529
-
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
-
Yamaguchi K., Nagai S., Ninomiya-Tsuji J., Nishita M., Tamai K., Irie K., et al. XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J 1999, 18:179-187.
-
(1999)
EMBO J
, vol.18
, pp. 179-187
-
-
Yamaguchi, K.1
Nagai, S.2
Ninomiya-Tsuji, J.3
Nishita, M.4
Tamai, K.5
Irie, K.6
-
70
-
-
0029940355
-
TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction
-
Shibuya H., Yamaguchi K., Shirakabe K., Tonegawa A., Gotoh Y., Ueno N., et al. TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science 1996, 272:1179-1182.
-
(1996)
Science
, vol.272
, pp. 1179-1182
-
-
Shibuya, H.1
Yamaguchi, K.2
Shirakabe, K.3
Tonegawa, A.4
Gotoh, Y.5
Ueno, N.6
-
71
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
Yamaguchi K., Shirakabe K., Shibuya H., Irie K., Oishi I., Ueno N., et al. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 1995, 270:2008-2011.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
-
72
-
-
67651174283
-
TAK1 is an essential regulator of BMP signalling in cartilage
-
Shim J.H., Greenblatt M.B., Xie M., Schneider M.D., Zou W., Zhai B., et al. TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J 2009, 28:2028-2041.
-
(2009)
EMBO J
, vol.28
, pp. 2028-2041
-
-
Shim, J.H.1
Greenblatt, M.B.2
Xie, M.3
Schneider, M.D.4
Zou, W.5
Zhai, B.6
-
73
-
-
38949213376
-
Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation
-
Corriere M.A., Rogers C.M., Eliason J.L., Faulk J., Kume T., Hogan B.L., et al. Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation. J Surg Res 2008, 145:142-149.
-
(2008)
J Surg Res
, vol.145
, pp. 142-149
-
-
Corriere, M.A.1
Rogers, C.M.2
Eliason, J.L.3
Faulk, J.4
Kume, T.5
Hogan, B.L.6
-
74
-
-
0027285583
-
Bone morphogenetic protein expression in human atherosclerotic lesions
-
Bostrom K., Watson K.E., Horn S., Wortham C., Herman I.M., Demer L.L. Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest 1993, 91:1800-1809.
-
(1993)
J Clin Invest
, vol.91
, pp. 1800-1809
-
-
Bostrom, K.1
Watson, K.E.2
Horn, S.3
Wortham, C.4
Herman, I.M.5
Demer, L.L.6
-
75
-
-
0043234315
-
Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response
-
Sorescu G.P., Sykes M., Weiss D., Platt M.O., Saha A., Hwang J., et al. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. J Biol Chem 2003, 278:31128-31135.
-
(2003)
J Biol Chem
, vol.278
, pp. 31128-31135
-
-
Sorescu, G.P.1
Sykes, M.2
Weiss, D.3
Platt, M.O.4
Saha, A.5
Hwang, J.6
-
76
-
-
18544384985
-
Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure
-
Csiszar A., Smith K.E., Koller A., Kaley G., Edwards J.G., Ungvari Z. Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure. Circulation 2005, 111:2364-2372.
-
(2005)
Circulation
, vol.111
, pp. 2364-2372
-
-
Csiszar, A.1
Smith, K.E.2
Koller, A.3
Kaley, G.4
Edwards, J.G.5
Ungvari, Z.6
-
77
-
-
0031470417
-
Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2
-
Nakaoka T., Gonda K., Ogita T., Otawara-Hamamoto Y., Okabe F., Kira Y., et al. Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2. J Clin Invest 1997, 100:2824-2832.
-
(1997)
J Clin Invest
, vol.100
, pp. 2824-2832
-
-
Nakaoka, T.1
Gonda, K.2
Ogita, T.3
Otawara-Hamamoto, Y.4
Okabe, F.5
Kira, Y.6
-
78
-
-
33745946837
-
Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation
-
Miriyala S., Gongora Nieto M.C., Mingone C., Smith D., Dikalov S., Harrison D.G., et al. Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation. Circulation 2006, 113:2818-2825.
-
(2006)
Circulation
, vol.113
, pp. 2818-2825
-
-
Miriyala, S.1
Gongora Nieto, M.C.2
Mingone, C.3
Smith, D.4
Dikalov, S.5
Harrison, D.G.6
-
79
-
-
33144469523
-
Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype
-
Csiszar A., Ahmad M., Smith K.E., Labinskyy N., Gao Q., Kaley G., et al. Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol 2006, 168:629-638.
-
(2006)
Am J Pathol
, vol.168
, pp. 629-638
-
-
Csiszar, A.1
Ahmad, M.2
Smith, K.E.3
Labinskyy, N.4
Gao, Q.5
Kaley, G.6
-
80
-
-
6344283050
-
Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase
-
Sorescu G.P., Song H., Tressel S.L., Hwang J., Dikalov S., Smith D.A., et al. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Circ Res 2004, 95:773-779.
-
(2004)
Circ Res
, vol.95
, pp. 773-779
-
-
Sorescu, G.P.1
Song, H.2
Tressel, S.L.3
Hwang, J.4
Dikalov, S.5
Smith, D.A.6
-
81
-
-
52449102202
-
Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells
-
Csiszar A., Labinskyy N., Jo H., Ballabh P., Ungvari Z. Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am J Physiol Heart Circ Physiol 2008, 295:H569-H577.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Csiszar, A.1
Labinskyy, N.2
Jo, H.3
Ballabh, P.4
Ungvari, Z.5
-
82
-
-
24744471858
-
Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension
-
Frank D.B., Abtahi A., Yamaguchi D.J., Manning S., Shyr Y., Pozzi A., et al. Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension. Circ Res 2005, 97:496-504.
-
(2005)
Circ Res
, vol.97
, pp. 496-504
-
-
Frank, D.B.1
Abtahi, A.2
Yamaguchi, D.J.3
Manning, S.4
Shyr, Y.5
Pozzi, A.6
-
83
-
-
0020570619
-
Pulmonary hypertension. Anatomic and physiologic correlates
-
Meyrick B., Reid L. Pulmonary hypertension. Anatomic and physiologic correlates. Clin Chest Med 1983, 4:199-217.
-
(1983)
Clin Chest Med
, vol.4
, pp. 199-217
-
-
Meyrick, B.1
Reid, L.2
-
84
-
-
77749328893
-
Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension
-
Anderson L., Lowery J.W., Frank D.B., Novitskaya T., Jones M., Mortlock D.P., et al. Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension. Am J Physiol Regul Integr Comp Physiol 2010, 298:R833-R842.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
-
-
Anderson, L.1
Lowery, J.W.2
Frank, D.B.3
Novitskaya, T.4
Jones, M.5
Mortlock, D.P.6
-
85
-
-
33751074163
-
BMP-dependent activation of caspase-9 and caspase-8 mediates apoptosis in pulmonary artery smooth muscle cells
-
Lagna G., Nguyen P.H., Ni W., Hata A. BMP-dependent activation of caspase-9 and caspase-8 mediates apoptosis in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2006, 291:L1059-L1067.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Lagna, G.1
Nguyen, P.H.2
Ni, W.3
Hata, A.4
-
86
-
-
4344684087
-
Characterization of the bone morphogenetic protein (BMP) system in human pulmonary arterial smooth muscle cells isolated from a sporadic case of primary pulmonary hypertension: roles of BMP type IB receptor (activin receptor-like kinase-6) in the mitotic action
-
Takeda M., Otsuka F., Nakamura K., Inagaki K., Suzuki J., Miura D., et al. Characterization of the bone morphogenetic protein (BMP) system in human pulmonary arterial smooth muscle cells isolated from a sporadic case of primary pulmonary hypertension: roles of BMP type IB receptor (activin receptor-like kinase-6) in the mitotic action. Endocrinology 2004, 145:4344-4354.
-
(2004)
Endocrinology
, vol.145
, pp. 4344-4354
-
-
Takeda, M.1
Otsuka, F.2
Nakamura, K.3
Inagaki, K.4
Suzuki, J.5
Miura, D.6
-
87
-
-
20344362689
-
Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension
-
Yang X., Long L., Southwood M., Rudarakanchana N., Upton P.D., Jeffery T.K., et al. Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension. Circ Res 2005, 96:1053-1063.
-
(2005)
Circ Res
, vol.96
, pp. 1053-1063
-
-
Yang, X.1
Long, L.2
Southwood, M.3
Rudarakanchana, N.4
Upton, P.D.5
Jeffery, T.K.6
-
88
-
-
40749102181
-
Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature
-
Frank D.B., Lowery J., Anderson L., Brink M., Reese J., de Caestecker M. Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature. Am J Physiol Lung Cell Mol Physiol 2008, 294:L98-L109.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Frank, D.B.1
Lowery, J.2
Anderson, L.3
Brink, M.4
Reese, J.5
de Caestecker, M.6
-
89
-
-
64049114344
-
A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum
-
Herrera B., Inman G.J. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol 2009, 10:20.
-
(2009)
BMC Cell Biol
, vol.10
, pp. 20
-
-
Herrera, B.1
Inman, G.J.2
-
90
-
-
42549158413
-
Bone morphogenetic protein-9 is a circulating vascular quiescence factor
-
David L., Mallet C., Keramidas M., Lamande N., Gasc J.M., Dupuis-Girod S., et al. Bone morphogenetic protein-9 is a circulating vascular quiescence factor. Circ Res 2008, 102:914-922.
-
(2008)
Circ Res
, vol.102
, pp. 914-922
-
-
David, L.1
Mallet, C.2
Keramidas, M.3
Lamande, N.4
Gasc, J.M.5
Dupuis-Girod, S.6
-
91
-
-
54449100051
-
BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis
-
Heinke J., Wehofsits L., Zhou Q., Zoeller C., Baar K.M., Helbing T., et al. BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis. Circ Res 2008, 103:804-812.
-
(2008)
Circ Res
, vol.103
, pp. 804-812
-
-
Heinke, J.1
Wehofsits, L.2
Zhou, Q.3
Zoeller, C.4
Baar, K.M.5
Helbing, T.6
-
92
-
-
33947588820
-
Gene expression profiles identify a role for cyclooxygenase 2-dependent prostanoid generation in BMP6-induced angiogenic responses
-
Ren R., Charles P.C., Zhang C., Wu Y., Wang H., Patterson C. Gene expression profiles identify a role for cyclooxygenase 2-dependent prostanoid generation in BMP6-induced angiogenic responses. Blood 2007, 109:2847-2853.
-
(2007)
Blood
, vol.109
, pp. 2847-2853
-
-
Ren, R.1
Charles, P.C.2
Zhang, C.3
Wu, Y.4
Wang, H.5
Patterson, C.6
-
93
-
-
39149099992
-
Gremlin promotes vascular smooth muscle cell proliferation and migration
-
Maciel T.T., Melo R.S., Schor N., Campos A.H. Gremlin promotes vascular smooth muscle cell proliferation and migration. J Mol Cell Cardiol 2008, 44:370-379.
-
(2008)
J Mol Cell Cardiol
, vol.44
, pp. 370-379
-
-
Maciel, T.T.1
Melo, R.S.2
Schor, N.3
Campos, A.H.4
-
94
-
-
65349196385
-
Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia
-
Jara A., Chacon C., Burgos M.E., Droguett A., Valdivieso A., Ortiz M., et al. Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia. Nephrol Dial Transplant 2009, 24:1121-1129.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 1121-1129
-
-
Jara, A.1
Chacon, C.2
Burgos, M.E.3
Droguett, A.4
Valdivieso, A.5
Ortiz, M.6
-
95
-
-
52149085463
-
Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension
-
Costello C.M., Howell K., Cahill E., McBryan J., Konigshoff M., Eickelberg O., et al. Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2008, 295:L272-L284.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Costello, C.M.1
Howell, K.2
Cahill, E.3
McBryan, J.4
Konigshoff, M.5
Eickelberg, O.6
-
96
-
-
34948907257
-
Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries: role of bone morphogenic protein antagonists in inflammation and atherosclerosis
-
Chang K., Weiss D., Suo J., Vega J.D., Giddens D., Taylor W.R., et al. Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries: role of bone morphogenic protein antagonists in inflammation and atherosclerosis. Circulation 2007, 116:1258-1266.
-
(2007)
Circulation
, vol.116
, pp. 1258-1266
-
-
Chang, K.1
Weiss, D.2
Suo, J.3
Vega, J.D.4
Giddens, D.5
Taylor, W.R.6
-
97
-
-
34548151204
-
BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish
-
Moser M., Yu Q., Bode C., Xiong J.W., Patterson C. BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish. J Mol Cell Cardiol 2007, 43:243-253.
-
(2007)
J Mol Cell Cardiol
, vol.43
, pp. 243-253
-
-
Moser, M.1
Yu, Q.2
Bode, C.3
Xiong, J.W.4
Patterson, C.5
-
98
-
-
0037040197
-
Matrix GLA protein, a regulatory protein for bone morphogenetic protein-2
-
Zebboudj A.F., Imura M., Boström K. Matrix GLA protein, a regulatory protein for bone morphogenetic protein-2. J Biol Chem 2002, 277:4388-4394.
-
(2002)
J Biol Chem
, vol.277
, pp. 4388-4394
-
-
Zebboudj, A.F.1
Imura, M.2
Boström, K.3
-
99
-
-
33845921834
-
Regulation of bone morphogenetic protein-4 by matrix GLA protein in vascular endothelial cells involves activin-like kinase receptor 1
-
Yao Y., Zebboudj A.F., Shao E., Perez M., Bostrom K. Regulation of bone morphogenetic protein-4 by matrix GLA protein in vascular endothelial cells involves activin-like kinase receptor 1. J Biol Chem 2006, 281:33921-33930.
-
(2006)
J Biol Chem
, vol.281
, pp. 33921-33930
-
-
Yao, Y.1
Zebboudj, A.F.2
Shao, E.3
Perez, M.4
Bostrom, K.5
-
100
-
-
0030947025
-
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
-
Luo G., Ducy P., McKee M.D., Pinero G.J., Loyer E., Behringer R.R., et al. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature 1997, 386:78-81.
-
(1997)
Nature
, vol.386
, pp. 78-81
-
-
Luo, G.1
Ducy, P.2
McKee, M.D.3
Pinero, G.J.4
Loyer, E.5
Behringer, R.R.6
-
101
-
-
18244394309
-
A novel MGP mutation in a consanguineous family: review of the clinical and molecular characteristics of Keutel syndrome
-
Hur D.J., Raymond G.V., Kahler S.G., Riegert-Johnson D.L., Cohen B.A., Boyadjiev S.A. A novel MGP mutation in a consanguineous family: review of the clinical and molecular characteristics of Keutel syndrome. Am J Med Genet A 2005, 135:36-40.
-
(2005)
Am J Med Genet A
, vol.135
, pp. 36-40
-
-
Hur, D.J.1
Raymond, G.V.2
Kahler, S.G.3
Riegert-Johnson, D.L.4
Cohen, B.A.5
Boyadjiev, S.A.6
-
102
-
-
35649010993
-
Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development
-
Yao Y., Nowak S., Yochelis A., Garfinkel A., Bostrom K.I. Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development. J Biol Chem 2007, 282:30131-30142.
-
(2007)
J Biol Chem
, vol.282
, pp. 30131-30142
-
-
Yao, Y.1
Nowak, S.2
Yochelis, A.3
Garfinkel, A.4
Bostrom, K.I.5
-
103
-
-
32544458797
-
Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension
-
Machado R.D., Aldred M.A., James V., Harrison R.E., Patel B., Schwalbe E.C., et al. Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum Mutat 2006, 27:121-132.
-
(2006)
Hum Mutat
, vol.27
, pp. 121-132
-
-
Machado, R.D.1
Aldred, M.A.2
James, V.3
Harrison, R.E.4
Patel, B.5
Schwalbe, E.C.6
-
104
-
-
67649573380
-
Genetics and genomics of pulmonary arterial hypertension
-
Machado R.D., Eickelberg O., Elliott C.G., Geraci M.W., Hanaoka M., Loyd J.E., et al. Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol 2009, 54:S32-S42.
-
(2009)
J Am Coll Cardiol
, vol.54
-
-
Machado, R.D.1
Eickelberg, O.2
Elliott, C.G.3
Geraci, M.W.4
Hanaoka, M.5
Loyd, J.E.6
-
105
-
-
2942522878
-
Clinical classification of pulmonary hypertension
-
Simonneau G., Galie N., Rubin L.J., Langleben D., Seeger W., Domenighetti G., et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol 2004, 43:5S-12S.
-
(2004)
J Am Coll Cardiol
, vol.43
-
-
Simonneau, G.1
Galie, N.2
Rubin, L.J.3
Langleben, D.4
Seeger, W.5
Domenighetti, G.6
-
106
-
-
0037421604
-
Signaling molecules in nonfamilial pulmonary hypertension
-
Du L., Sullivan C.C., Chu D., Cho A.J., Kido M., Wolf P.L., et al. Signaling molecules in nonfamilial pulmonary hypertension. N Engl J Med 2003, 348:500-509.
-
(2003)
N Engl J Med
, vol.348
, pp. 500-509
-
-
Du, L.1
Sullivan, C.C.2
Chu, D.3
Cho, A.J.4
Kido, M.5
Wolf, P.L.6
-
107
-
-
0037046175
-
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor
-
Atkinson C., Stewart S., Upton P.D., Machado R., Thomson J.R., Trembath R.C., et al. Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor. Circulation 2002, 105:1672-1678.
-
(2002)
Circulation
, vol.105
, pp. 1672-1678
-
-
Atkinson, C.1
Stewart, S.2
Upton, P.D.3
Machado, R.4
Thomson, J.R.5
Trembath, R.C.6
-
108
-
-
34548853386
-
Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity
-
Liu D., Wang J., Kinzel B., Mueller M., Mao X., Valdez R., et al. Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity. Blood 2007, 110:1502-1510.
-
(2007)
Blood
, vol.110
, pp. 1502-1510
-
-
Liu, D.1
Wang, J.2
Kinzel, B.3
Mueller, M.4
Mao, X.5
Valdez, R.6
-
109
-
-
50349096148
-
Genetic ablation of the Bmpr2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension
-
Hong K.-H., Lee Y.J., Lee E., Park S.O., Han C., Beppu H., et al. Genetic ablation of the Bmpr2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension. Circulation 2008, 118:722-730.
-
(2008)
Circulation
, vol.118
, pp. 722-730
-
-
Hong, K.-H.1
Lee, Y.J.2
Lee, E.3
Park, S.O.4
Han, C.5
Beppu, H.6
-
110
-
-
57049159708
-
Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions
-
West J., Harral J., Lane K., Deng Y., Ickes B., Crona D., et al. Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions. Am J Physiol Lung Cell Mol Physiol 2008, 295:L744-L755.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
West, J.1
Harral, J.2
Lane, K.3
Deng, Y.4
Ickes, B.5
Crona, D.6
-
111
-
-
67649844313
-
Inflammation, growth factors, and pulmonary vascular remodeling
-
Hassoun P.M., Mouthon L., Barbera J.A., Eddahibi S., Flores S.C., Grimminger F., et al. Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol 2009, 54:S10-S19.
-
(2009)
J Am Coll Cardiol
, vol.54
-
-
Hassoun, P.M.1
Mouthon, L.2
Barbera, J.A.3
Eddahibi, S.4
Flores, S.C.5
Grimminger, F.6
-
112
-
-
52449108680
-
Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice
-
Song Y., Coleman L., Shi J., Beppu H., Sato K., Walsh K., et al. Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice. Am J Physiol Heart Circ Physiol 2008, 295:H677-H690.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Song, Y.1
Coleman, L.2
Shi, J.3
Beppu, H.4
Sato, K.5
Walsh, K.6
-
113
-
-
23044504042
-
Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice
-
Song Y., Jones J.E., Beppu H., Keaney J.F., Loscalzo J., Zhang Y.Y. Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice. Circulation 2005, 112:553-562.
-
(2005)
Circulation
, vol.112
, pp. 553-562
-
-
Song, Y.1
Jones, J.E.2
Beppu, H.3
Keaney, J.F.4
Loscalzo, J.5
Zhang, Y.Y.6
-
114
-
-
33645751955
-
Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice
-
Long L., MacLean M.R., Jeffery T.K., Morecroft I., Yang X., Rudarakanchana N., et al. Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice. Circ Res 2006, 98:818-827.
-
(2006)
Circ Res
, vol.98
, pp. 818-827
-
-
Long, L.1
MacLean, M.R.2
Jeffery, T.K.3
Morecroft, I.4
Yang, X.5
Rudarakanchana, N.6
-
115
-
-
8644256840
-
BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia
-
Beppu H., Ichinose F., Kawai N., Jones R.C., Yu P.B., Zapol W.M., et al. BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol Lung Cell Mol Physiol 2004, 287:L1241-L1247.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Beppu, H.1
Ichinose, F.2
Kawai, N.3
Jones, R.C.4
Yu, P.B.5
Zapol, W.M.6
-
116
-
-
0033795729
-
Hypoxia-induced pulmonary vascular remodeling: a model for what human disease?
-
Voelkel N.F., Tuder R.M. Hypoxia-induced pulmonary vascular remodeling: a model for what human disease?. J Clin Invest 2000, 106:733-738.
-
(2000)
J Clin Invest
, vol.106
, pp. 733-738
-
-
Voelkel, N.F.1
Tuder, R.M.2
-
117
-
-
34250172107
-
Hereditary hemorrhagic telangiectasia: clinical features in ENG and ALK1 mutation carriers
-
Sabba C., Pasculli G., Lenato G.M., Suppressa P., Lastella P., Memeo M., et al. Hereditary hemorrhagic telangiectasia: clinical features in ENG and ALK1 mutation carriers. J Thromb Haemost 2007, 5:1149-1157.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1149-1157
-
-
Sabba, C.1
Pasculli, G.2
Lenato, G.M.3
Suppressa, P.4
Lastella, P.5
Memeo, M.6
-
118
-
-
12944273545
-
Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis
-
Oh S.P., Seki T., Goss K.A., Imamura T., Yi Y., Donahoe P.K., et al. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci USA 2000, 97:2626-2631.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2626-2631
-
-
Oh, S.P.1
Seki, T.2
Goss, K.A.3
Imamura, T.4
Yi, Y.5
Donahoe, P.K.6
-
119
-
-
0033757655
-
Arteriovenous malformations in mice lacking activin receptor-like kinase-1
-
Urness L.D., Sorensen L.K., Li D.Y. Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet 2000, 26:328-331.
-
(2000)
Nat Genet
, vol.26
, pp. 328-331
-
-
Urness, L.D.1
Sorensen, L.K.2
Li, D.Y.3
-
120
-
-
0033621804
-
Endoglin, an ancillary TGF[beta] receptor, is required for extraembryonic angiogenesis and plays a key role in heart development
-
Arthur H.M., Ure J., Smith A.J.H., Renforth G., Wilson D.I., Torsney E., et al. Endoglin, an ancillary TGF[beta] receptor, is required for extraembryonic angiogenesis and plays a key role in heart development. Dev Biol 2000, 217:42-53.
-
(2000)
Dev Biol
, vol.217
, pp. 42-53
-
-
Arthur, H.M.1
Ure, J.2
Smith, A.J.H.3
Renforth, G.4
Wilson, D.I.5
Torsney, E.6
-
121
-
-
0037341510
-
A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2
-
Srinivasan S., Hanes M.A., Dickens T., Porteous M.E., Oh S.P., Hale L.P., et al. A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2. Hum Mol Genet 2003, 12:473-482.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 473-482
-
-
Srinivasan, S.1
Hanes, M.A.2
Dickens, T.3
Porteous, M.E.4
Oh, S.P.5
Hale, L.P.6
-
122
-
-
38349173601
-
ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2
-
Park S.O., Lee Y.J., Seki T., Hong K.-H., Fliess N., Jiang Z., et al. ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2. Blood 2008, 111:633-642.
-
(2008)
Blood
, vol.111
, pp. 633-642
-
-
Park, S.O.1
Lee, Y.J.2
Seki, T.3
Hong, K.-H.4
Fliess, N.5
Jiang, Z.6
-
123
-
-
9144219585
-
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
-
Harrison R.E., Flanagan J.A., Sankelo M., Abdalla S.A., Rowell J., Machado R.D., et al. Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia. J Med Genet 2003, 40:865-871.
-
(2003)
J Med Genet
, vol.40
, pp. 865-871
-
-
Harrison, R.E.1
Flanagan, J.A.2
Sankelo, M.3
Abdalla, S.A.4
Rowell, J.5
Machado, R.D.6
-
124
-
-
33749379585
-
Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation
-
Park C., Lavine K., Mishina Y., Deng C.X., Ornitz D.M., Choi K. Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development 2006, 133:3473-3484.
-
(2006)
Development
, vol.133
, pp. 3473-3484
-
-
Park, C.1
Lavine, K.2
Mishina, Y.3
Deng, C.X.4
Ornitz, D.M.5
Choi, K.6
-
125
-
-
39449096751
-
Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling
-
El-Bizri N., Wang L., Merklinger S.L., Guignabert C., Desai T., Urashima T., et al. Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling. Circ Res 2008, 102:380-388.
-
(2008)
Circ Res
, vol.102
, pp. 380-388
-
-
El-Bizri, N.1
Wang, L.2
Merklinger, S.L.3
Guignabert, C.4
Desai, T.5
Urashima, T.6
-
126
-
-
0028171579
-
Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1
-
McAllister K.A., Grogg K.M., Johnson D.W., Gallione C.J., Baldwin M.A., Jackson C.E., et al. Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. Nat Genet 1994, 8:345-351.
-
(1994)
Nat Genet
, vol.8
, pp. 345-351
-
-
McAllister, K.A.1
Grogg, K.M.2
Johnson, D.W.3
Gallione, C.J.4
Baldwin, M.A.5
Jackson, C.E.6
-
127
-
-
0034443720
-
Endoglin-deficient mice, a unique model to study hereditary hemorrhagic telangiectasia
-
Bourdeau A., Faughnan M.E., Letarte M. Endoglin-deficient mice, a unique model to study hereditary hemorrhagic telangiectasia. Trends Cardiovasc Med 2000, 10:279-285.
-
(2000)
Trends Cardiovasc Med
, vol.10
, pp. 279-285
-
-
Bourdeau, A.1
Faughnan, M.E.2
Letarte, M.3
-
128
-
-
77649135502
-
Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia
-
Toporsian M., Jerkic M., Zhou Y.Q., Kabir M.G., Yu L.X., McIntyre B.A., et al. Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia. Arterioscler Thromb Vasc Biol 2010, 30:509-517.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 509-517
-
-
Toporsian, M.1
Jerkic, M.2
Zhou, Y.Q.3
Kabir, M.G.4
Yu, L.X.5
McIntyre, B.A.6
-
129
-
-
71949131399
-
Age-dependent endothelial nitric oxide synthase uncoupling in pulmonary arteries of endoglin heterozygous mice
-
Belik J., Jerkic M., McIntyre B.A.S., Pan J., Leen J., Yu L.X., et al. Age-dependent endothelial nitric oxide synthase uncoupling in pulmonary arteries of endoglin heterozygous mice. Am J Physiol Lung Cell Mol Physiol 2009, 297:L1170-L1178.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Belik, J.1
Jerkic, M.2
McIntyre, B.A.S.3
Pan, J.4
Leen, J.5
Yu, L.X.6
-
130
-
-
67649227647
-
Preeclampsia: the role of angiogenic factors in its pathogenesis
-
Wang A., Rana S., Karumanchi S.A. Preeclampsia: the role of angiogenic factors in its pathogenesis. Physiology (Bethesda) 2009, 24:147-158.
-
(2009)
Physiology (Bethesda)
, vol.24
, pp. 147-158
-
-
Wang, A.1
Rana, S.2
Karumanchi, S.A.3
-
131
-
-
0027259431
-
Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions
-
Bellon T., Corbi A., Lastres P., Cales C., Cebrian M., Vera S., et al. Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. Eur J Immunol 1993, 23:2340-2345.
-
(1993)
Eur J Immunol
, vol.23
, pp. 2340-2345
-
-
Bellon, T.1
Corbi, A.2
Lastres, P.3
Cales, C.4
Cebrian, M.5
Vera, S.6
-
132
-
-
21744455455
-
Characterization of murine S-endoglin isoform and its effects on tumor development
-
Perez-Gomez E., Eleno N., Lopez-Novoa J.M., Ramirez J.R., Velasco B., Letarte M., et al. Characterization of murine S-endoglin isoform and its effects on tumor development. Oncogene 2005, 24:4450-4461.
-
(2005)
Oncogene
, vol.24
, pp. 4450-4461
-
-
Perez-Gomez, E.1
Eleno, N.2
Lopez-Novoa, J.M.3
Ramirez, J.R.4
Velasco, B.5
Letarte, M.6
-
133
-
-
58149218908
-
S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology
-
Blanco F.J., Grande M.T., Langa C., Oujo B., Velasco S., Rodriguez-Barbero A., et al. S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology. Circ Res 2008, 103:1383-1392.
-
(2008)
Circ Res
, vol.103
, pp. 1383-1392
-
-
Blanco, F.J.1
Grande, M.T.2
Langa, C.3
Oujo, B.4
Velasco, S.5
Rodriguez-Barbero, A.6
-
135
-
-
33745958768
-
Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo
-
Arnold S.J., Maretto S., Islam A., Bikoff E.K., Robertson E.J. Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol 2006, 296:104-118.
-
(2006)
Dev Biol
, vol.296
, pp. 104-118
-
-
Arnold, S.J.1
Maretto, S.2
Islam, A.3
Bikoff, E.K.4
Robertson, E.J.5
-
136
-
-
0032908432
-
Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects
-
Chang H., Huylebroeck D., Verschueren K., Guo Q., Matzuk M.M., Zwijsen A. Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development 1999, 126:1631-1642.
-
(1999)
Development
, vol.126
, pp. 1631-1642
-
-
Chang, H.1
Huylebroeck, D.2
Verschueren, K.3
Guo, Q.4
Matzuk, M.M.5
Zwijsen, A.6
-
137
-
-
0032960886
-
Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5
-
Yang X., Castilla L.H., Xu X., Li C., Gotay J., Weinstein M., et al. Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5. Development 1999, 126:1571-1580.
-
(1999)
Development
, vol.126
, pp. 1571-1580
-
-
Yang, X.1
Castilla, L.H.2
Xu, X.3
Li, C.4
Gotay, J.5
Weinstein, M.6
-
138
-
-
34250844456
-
Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis
-
Umans L., Cox L., Tjwa M., Bito V., Vermeire L., Laperre K., et al. Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis. Am J Pathol 2007, 170:1460-1472.
-
(2007)
Am J Pathol
, vol.170
, pp. 1460-1472
-
-
Umans, L.1
Cox, L.2
Tjwa, M.3
Bito, V.4
Vermeire, L.5
Laperre, K.6
-
139
-
-
0035581323
-
Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion
-
Lechleider R.J., Ryan J.L., Garrett L., Eng C., Deng C., Wynshaw-Boris A., et al. Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion. Dev Biol 2001, 240:157-167.
-
(2001)
Dev Biol
, vol.240
, pp. 157-167
-
-
Lechleider, R.J.1
Ryan, J.L.2
Garrett, L.3
Eng, C.4
Deng, C.5
Wynshaw-Boris, A.6
-
140
-
-
67650721435
-
Defective pulmonary vascular remodeling in Smad8 mutant mice
-
Huang Z., Wang D., Ihida-Stansbury K., Jones P.L., Martin J.F. Defective pulmonary vascular remodeling in Smad8 mutant mice. Hum Mol Genet 2009, 18:2791-2801.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 2791-2801
-
-
Huang, Z.1
Wang, D.2
Ihida-Stansbury, K.3
Jones, P.L.4
Martin, J.F.5
-
141
-
-
66249125359
-
A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension
-
Shintani M., Yagi H., Nakayama T., Saji T., Matsuoka R. A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension. J Med Genet 2009, 46:331-337.
-
(2009)
J Med Genet
, vol.46
, pp. 331-337
-
-
Shintani, M.1
Yagi, H.2
Nakayama, T.3
Saji, T.4
Matsuoka, R.5
-
142
-
-
3142746721
-
The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations
-
Howe J.R., Sayed M.G., Ahmed A.F., Ringold J., Larsen-Haidle J., Merg A., et al. The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations. J Med Genet 2004, 41:484-491.
-
(2004)
J Med Genet
, vol.41
, pp. 484-491
-
-
Howe, J.R.1
Sayed, M.G.2
Ahmed, A.F.3
Ringold, J.4
Larsen-Haidle, J.5
Merg, A.6
-
143
-
-
15444348295
-
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo
-
Sirard C., de la Pompa J.L., Elia A., Itie A., Mirtsos C., Cheung A., et al. The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. Genes Dev 1998, 12:107-119.
-
(1998)
Genes Dev
, vol.12
, pp. 107-119
-
-
Sirard, C.1
de la Pompa, J.L.2
Elia, A.3
Itie, A.4
Mirtsos, C.5
Cheung, A.6
-
144
-
-
0032584068
-
The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice
-
Yang X., Li C., Xu X., Deng C. The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. Proc Natl Acad Sci USA 1998, 95:3667-3672.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3667-3672
-
-
Yang, X.1
Li, C.2
Xu, X.3
Deng, C.4
-
145
-
-
0033612141
-
Defective angiogenesis in mice lacking endoglin
-
Li D.Y., Sorensen L.K., Brooke B.S., Urness L.D., Davis E.C., Taylor D.G., et al. Defective angiogenesis in mice lacking endoglin. Science 1999, 284:1534-1537.
-
(1999)
Science
, vol.284
, pp. 1534-1537
-
-
Li, D.Y.1
Sorensen, L.K.2
Brooke, B.S.3
Urness, L.D.4
Davis, E.C.5
Taylor, D.G.6
-
146
-
-
35648947847
-
Essential role of endothelial Smad4 in vascular remodeling and integrity
-
Lan Y., Liu B., Yao H., Li F., Weng T., Yang G., et al. Essential role of endothelial Smad4 in vascular remodeling and integrity. Mol Cell Biol 2007, 27:7683-7692.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7683-7692
-
-
Lan, Y.1
Liu, B.2
Yao, H.3
Li, F.4
Weng, T.5
Yang, G.6
-
147
-
-
17444453852
-
A role for smad6 in development and homeostasis of the cardiovascular system
-
Galvin K.M., Donovan M.J., Lynch C.A., Meyer R.I., Paul R.J., Lorenz J.N., et al. A role for smad6 in development and homeostasis of the cardiovascular system. Nat Genet 2000, 24:171-174.
-
(2000)
Nat Genet
, vol.24
, pp. 171-174
-
-
Galvin, K.M.1
Donovan, M.J.2
Lynch, C.A.3
Meyer, R.I.4
Paul, R.J.5
Lorenz, J.N.6
-
148
-
-
33646713486
-
The TGF beta activated kinase TAK1 regulates vascular development in vivo
-
Jadrich J.L., O'Connor M.B., Coucouvanis E. The TGF beta activated kinase TAK1 regulates vascular development in vivo. Development 2006, 133:1529-1541.
-
(2006)
Development
, vol.133
, pp. 1529-1541
-
-
Jadrich, J.L.1
O'Connor, M.B.2
Coucouvanis, E.3
-
149
-
-
70849128432
-
Applications of small molecule BMP inhibitors in physiology and disease
-
Hong C.C., Yu P.B. Applications of small molecule BMP inhibitors in physiology and disease. Cytokine Growth Factor Rev 2009, 20:409-418.
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, pp. 409-418
-
-
Hong, C.C.1
Yu, P.B.2
-
150
-
-
70349260659
-
Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells
-
Shao E.S., Lin L., Yao Y., Bostrom K.I. Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells. Blood 2009, 114:2197-2206.
-
(2009)
Blood
, vol.114
, pp. 2197-2206
-
-
Shao, E.S.1
Lin, L.2
Yao, Y.3
Bostrom, K.I.4
-
151
-
-
33847369980
-
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
-
David L., Mallet C., Mazerbourg S., Feige J.-J., Bailly S. Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 2007, 109:1953-1961.
-
(2007)
Blood
, vol.109
, pp. 1953-1961
-
-
David, L.1
Mallet, C.2
Mazerbourg, S.3
Feige, J.-J.4
Bailly, S.5
-
152
-
-
76649106431
-
ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth
-
Mitchell D., Pobre E.G., Mulivor A.W., Grinberg A.V., Castonguay R., Monnell T.E., et al. ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth. Mol Cancer Ther 2010, 9:379-388.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 379-388
-
-
Mitchell, D.1
Pobre, E.G.2
Mulivor, A.W.3
Grinberg, A.V.4
Castonguay, R.5
Monnell, T.E.6
-
153
-
-
0032754669
-
Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation
-
Ebisawa T., Tada K., Kitajima I., Tojo K., Sampath T., Kawabata M., et al. Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation. J Cell Sci 1999, 112:3519-3527.
-
(1999)
J Cell Sci
, vol.112
, pp. 3519-3527
-
-
Ebisawa, T.1
Tada, K.2
Kitajima, I.3
Tojo, K.4
Sampath, T.5
Kawabata, M.6
-
154
-
-
0028332818
-
Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4
-
ten Dijke P., Yamashita H., Sampath T.K., Reddi A.H., Estevez M., Riddle D.L., et al. Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. J Biol Chem 1994, 269:16985-16988.
-
(1994)
J Biol Chem
, vol.269
, pp. 16985-16988
-
-
ten Dijke, P.1
Yamashita, H.2
Sampath, T.K.3
Reddi, A.H.4
Estevez, M.5
Riddle, D.L.6
-
155
-
-
0032475884
-
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2
-
Maci{dotless}óas-Silva M., Hoodless P.A., Tang S.J., Buchwald M., Wrana J.L. Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J Biol Chem 1998, 273:25628-25636.
-
(1998)
J Biol Chem
, vol.273
, pp. 25628-25636
-
-
Macióas-Silva, M.1
Hoodless, P.A.2
Tang, S.J.3
Buchwald, M.4
Wrana, J.L.5
-
156
-
-
0029003377
-
Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects
-
Yamashita H., ten Dijke P., Huylebroeck D., Sampath T.K., Andries M., Smith J.C., et al. Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects. J Cell Biol 1995, 130:217-226.
-
(1995)
J Cell Biol
, vol.130
, pp. 217-226
-
-
Yamashita, H.1
ten Dijke, P.2
Huylebroeck, D.3
Sampath, T.K.4
Andries, M.5
Smith, J.C.6
-
157
-
-
2342516135
-
Molecular recognition of BMP-2 and BMP receptor IA
-
Keller S., Nickel J., Zhang J.L., Sebald W., Mueller T.D. Molecular recognition of BMP-2 and BMP receptor IA. Nat Struct Mol Biol 2004, 11:481-488.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 481-488
-
-
Keller, S.1
Nickel, J.2
Zhang, J.L.3
Sebald, W.4
Mueller, T.D.5
-
158
-
-
0035088553
-
The crystal structure of the BMP-2:BMPR-IA complex and the generation of BMP-2 antagonists
-
Nickel J., Dreyer M.K., Kirsch T., Sebald W. The crystal structure of the BMP-2:BMPR-IA complex and the generation of BMP-2 antagonists. J Bone Joint Surg Am 2001, 83:S7-S14.
-
(2001)
J Bone Joint Surg Am
, vol.83
-
-
Nickel, J.1
Dreyer, M.K.2
Kirsch, T.3
Sebald, W.4
-
159
-
-
0028142801
-
Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells
-
Koenig B.B., Cook J.S., Wolsing D.H., Ting J., Tiesman J.P., Correa P.E., et al. Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. Mol Cell Biol 1994, 14:5961-5974.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5961-5974
-
-
Koenig, B.B.1
Cook, J.S.2
Wolsing, D.H.3
Ting, J.4
Tiesman, J.P.5
Correa, P.E.6
-
160
-
-
0034043106
-
Crystal structure of the BMP-2-BRIA ectodomain complex
-
Kirsch T., Sebald W., Dreyer M.K. Crystal structure of the BMP-2-BRIA ectodomain complex. Nat Struct Biol 2000, 7:492-496.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 492-496
-
-
Kirsch, T.1
Sebald, W.2
Dreyer, M.K.3
-
161
-
-
0033975972
-
Isolation of recombinant BMP receptor IA ectodomain and its 2:1 complex with BMP-2
-
Kirsch T., Nickel J., Sebald W. Isolation of recombinant BMP receptor IA ectodomain and its 2:1 complex with BMP-2. FEBS Lett 2000, 468:215-219.
-
(2000)
FEBS Lett
, vol.468
, pp. 215-219
-
-
Kirsch, T.1
Nickel, J.2
Sebald, W.3
-
162
-
-
0028572494
-
A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4
-
Yamaji N., Celeste A.J., Thies R.S., Song J.J., Bernier S.M., Goltzman D., et al. A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4. Biochem Biophys Res Commun 1994, 205:1944-1951.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1944-1951
-
-
Yamaji, N.1
Celeste, A.J.2
Thies, R.S.3
Song, J.J.4
Bernier, S.M.5
Goltzman, D.6
-
163
-
-
33646749327
-
Structure of the ternary signaling complex of a TGF-beta superfamily member
-
Allendorph G.P., Vale W.W., Choe S. Structure of the ternary signaling complex of a TGF-beta superfamily member. Proc Natl Acad Sci USA 2006, 103:7643-7648.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7643-7648
-
-
Allendorph, G.P.1
Vale, W.W.2
Choe, S.3
-
164
-
-
0034460683
-
Identification of the ligand-binding site of the BMP type IA receptor for BMP-4
-
Hatta T., Konishi H., Katoh E., Natsume T., Ueno N., Kobayashi Y., et al. Identification of the ligand-binding site of the BMP type IA receptor for BMP-4. Pept Sci 2000, 55:399-406.
-
(2000)
Pept Sci
, vol.55
, pp. 399-406
-
-
Hatta, T.1
Konishi, H.2
Katoh, E.3
Natsume, T.4
Ueno, N.5
Kobayashi, Y.6
-
165
-
-
0035789468
-
Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons
-
Beck H., Drahushuk K., Jacoby D., Higgins D., Lein P. Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons. BMC Neurosci 2001, 2:12.
-
(2001)
BMC Neurosci
, vol.2
, pp. 12
-
-
Beck, H.1
Drahushuk, K.2
Jacoby, D.3
Higgins, D.4
Lein, P.5
-
166
-
-
33745272290
-
Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/growth differentiation factor ligands
-
Mazerbourg S., Hsueh A.J. Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/growth differentiation factor ligands. Hum Reprod Update 2006, 12:373-383.
-
(2006)
Hum Reprod Update
, vol.12
, pp. 373-383
-
-
Mazerbourg, S.1
Hsueh, A.J.2
-
167
-
-
0031918786
-
Cartilage-derived morphogenetic proteins and osteogenic protein-1 differentially regulate osteogenesis
-
Erlacher L., McCartney J., Piek E., ten Dijke P., Yanagishita M., Oppermann H., et al. Cartilage-derived morphogenetic proteins and osteogenic protein-1 differentially regulate osteogenesis. J Bone Miner Res 1998, 13:383-392.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 383-392
-
-
Erlacher, L.1
McCartney, J.2
Piek, E.3
ten Dijke, P.4
Yanagishita, M.5
Oppermann, H.6
-
168
-
-
0029831660
-
Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5
-
Nishitoh H., Ichijo H., Kimura M., Matsumoto T., Makishima F., Yamaguchi A., et al. Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5. J Biol Chem 1996, 271:21345-21352.
-
(1996)
J Biol Chem
, vol.271
, pp. 21345-21352
-
-
Nishitoh, H.1
Ichijo, H.2
Kimura, M.3
Matsumoto, T.4
Makishima, F.5
Yamaguchi, A.6
-
169
-
-
0037414773
-
Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells
-
Moore R.K., Otsuka F., Shimasaki S. Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells. J Biol Chem 2003, 278:304-310.
-
(2003)
J Biol Chem
, vol.278
, pp. 304-310
-
-
Moore, R.K.1
Otsuka, F.2
Shimasaki, S.3
-
170
-
-
0034600953
-
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II
-
Kirsch T., Nickel J., Sebald W. BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II. EMBO J 2000, 19:3314-3324.
-
(2000)
EMBO J
, vol.19
, pp. 3314-3324
-
-
Kirsch, T.1
Nickel, J.2
Sebald, W.3
-
171
-
-
0029008597
-
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs
-
Liu F., Ventura F., Doody J., Massague J. Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Mol Cell Biol 1995, 15:3479-3486.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3479-3486
-
-
Liu, F.1
Ventura, F.2
Doody, J.3
Massague, J.4
-
172
-
-
0029117276
-
Cloning and characterization of a human type II receptor for bone morphogenetic proteins
-
Rosenzweig B.L., Imamura T., Okadome T., Cox G.N., Yamashita H., ten Dijke P., et al. Cloning and characterization of a human type II receptor for bone morphogenetic proteins. Proc Natl Acad Sci USA 1995, 92:7632-7636.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7632-7636
-
-
Rosenzweig, B.L.1
Imamura, T.2
Okadome, T.3
Cox, G.N.4
Yamashita, H.5
ten Dijke, P.6
-
173
-
-
34547124340
-
Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4
-
Xia Y., Yu P.B., Sidis Y., Beppu H., Bloch K.D., Schneyer A.L., et al. Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem 2007, 282:18129-18140.
-
(2007)
J Biol Chem
, vol.282
, pp. 18129-18140
-
-
Xia, Y.1
Yu, P.B.2
Sidis, Y.3
Beppu, H.4
Bloch, K.D.5
Schneyer, A.L.6
-
174
-
-
0037351880
-
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly
-
Greenwald J., Groppe J., Gray P., Wiater E., Kwiatkowski W., Vale W., et al. The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly. Mol Cell 2003, 11:605-617.
-
(2003)
Mol Cell
, vol.11
, pp. 605-617
-
-
Greenwald, J.1
Groppe, J.2
Gray, P.3
Wiater, E.4
Kwiatkowski, W.5
Vale, W.6
-
175
-
-
23844456919
-
Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor
-
Babitt J.L., Zhang Y., Samad T.A., Xia Y., Tang J., Campagna J.A., et al. Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem 2005, 280:29820-29827.
-
(2005)
J Biol Chem
, vol.280
, pp. 29820-29827
-
-
Babitt, J.L.1
Zhang, Y.2
Samad, T.A.3
Xia, Y.4
Tang, J.5
Campagna, J.A.6
-
176
-
-
34547759860
-
Role of RGM coreceptors in bone morphogenetic protein signaling
-
Halbrooks P.J., Ding R., Wozney J.M., Bain G. Role of RGM coreceptors in bone morphogenetic protein signaling. J Mol Signal 2007, 2:4.
-
(2007)
J Mol Signal
, vol.2
, pp. 4
-
-
Halbrooks, P.J.1
Ding, R.2
Wozney, J.M.3
Bain, G.4
-
177
-
-
20244375259
-
DRAGON, a bone morphogenetic protein co-receptor
-
Samad T.A., Rebbapragada A., Bell E., Zhang Y., Sidis Y., Jeong S.J., et al. DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem 2005, 280:14122-14129.
-
(2005)
J Biol Chem
, vol.280
, pp. 14122-14129
-
-
Samad, T.A.1
Rebbapragada, A.2
Bell, E.3
Zhang, Y.4
Sidis, Y.5
Jeong, S.J.6
-
178
-
-
41949115757
-
Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin
-
Kuns-Hashimoto R., Kuninger D., Nili M., Rotwein P. Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin. Am J Physiol Cell Physiol 2008, 294:C994-C1003.
-
(2008)
Am J Physiol Cell Physiol
, vol.294
-
-
Kuns-Hashimoto, R.1
Kuninger, D.2
Nili, M.3
Rotwein, P.4
-
179
-
-
41849096388
-
Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains
-
Yang F., West A.P., Allendorph G.P., Choe S., Bjorkman P.J. Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains. Biochemistry 2008, 47:4237-4245.
-
(2008)
Biochemistry
, vol.47
, pp. 4237-4245
-
-
Yang, F.1
West, A.P.2
Allendorph, G.P.3
Choe, S.4
Bjorkman, P.J.5
-
180
-
-
46749158788
-
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
-
Xia Y., Babitt J.L., Sidis Y., Chung R.T., Lin H.Y. Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood 2008, 111:5195-5204.
-
(2008)
Blood
, vol.111
, pp. 5195-5204
-
-
Xia, Y.1
Babitt, J.L.2
Sidis, Y.3
Chung, R.T.4
Lin, H.Y.5
-
181
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
-
Babitt J.L., Huang F.W., Wrighting D.M., Xia Y., Sidis Y., Samad T.A., et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 2006, 38:531-539.
-
(2006)
Nat Genet
, vol.38
, pp. 531-539
-
-
Babitt, J.L.1
Huang, F.W.2
Wrighting, D.M.3
Xia, Y.4
Sidis, Y.5
Samad, T.A.6
-
182
-
-
63449103712
-
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
-
Andriopoulos B., Corradini E., Xia Y., Faasse S.A., Chen S., Grgurevic L., et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet 2009, 41:482-487.
-
(2009)
Nat Genet
, vol.41
, pp. 482-487
-
-
Andriopoulos, B.1
Corradini, E.2
Xia, Y.3
Faasse, S.A.4
Chen, S.5
Grgurevic, L.6
-
183
-
-
0033619255
-
Silencing of TGF-beta signalling by the pseudoreceptor BAMBI
-
Onichtchouk D., Chen Y.G., Dosch R., Gawantka V., Delius H., Massague J., et al. Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature 1999, 401:480-485.
-
(1999)
Nature
, vol.401
, pp. 480-485
-
-
Onichtchouk, D.1
Chen, Y.G.2
Dosch, R.3
Gawantka, V.4
Delius, H.5
Massague, J.6
-
184
-
-
35448957195
-
TrkC binds to the bone morphogenetic protein type II receptor to suppress bone morphogenetic protein signaling
-
Jin W., Yun C., Kim H.S., Kim S.J. TrkC binds to the bone morphogenetic protein type II receptor to suppress bone morphogenetic protein signaling. Cancer Res 2007, 67:9869-9877.
-
(2007)
Cancer Res
, vol.67
, pp. 9869-9877
-
-
Jin, W.1
Yun, C.2
Kim, H.S.3
Kim, S.J.4
-
185
-
-
61849137766
-
Biochemical and functional characterization of the Ror2/BRIb receptor complex
-
Sammar M., Sieber C., Knaus P. Biochemical and functional characterization of the Ror2/BRIb receptor complex. Biochem Biophys Res Commun 2009, 381:1-6.
-
(2009)
Biochem Biophys Res Commun
, vol.381
, pp. 1-6
-
-
Sammar, M.1
Sieber, C.2
Knaus, P.3
-
186
-
-
10244267459
-
Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2
-
Sammar M., Stricker S., Schwabe G.C., Sieber C., Hartung A., Hanke M., et al. Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2. Genes Cells 2004, 9:1227-1238.
-
(2004)
Genes Cells
, vol.9
, pp. 1227-1238
-
-
Sammar, M.1
Stricker, S.2
Schwabe, G.C.3
Sieber, C.4
Hartung, A.5
Hanke, M.6
-
187
-
-
55449130745
-
BMPR2 mutation in a patient with pulmonary arterial hypertension and suspected hereditary hemorrhagic telangiectasia
-
A
-
Rigelsky C.M., Jennings C., Lehtonen R., Minai O.A., Eng C., Aldred M.A. BMPR2 mutation in a patient with pulmonary arterial hypertension and suspected hereditary hemorrhagic telangiectasia. Am J Med Genet A 2008, 146A:2551-2556.
-
(2008)
Am J Med Genet A
, vol.146
, pp. 2551-2556
-
-
Rigelsky, C.M.1
Jennings, C.2
Lehtonen, R.3
Minai, O.A.4
Eng, C.5
Aldred, M.A.6
-
188
-
-
70449392400
-
Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia
-
Park S.O., Wankhede M., Lee Y.J., Choi E.J., Fliess N., Choe S.W., et al. Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. J Clin Invest 2009, 119:3487-3496.
-
(2009)
J Clin Invest
, vol.119
, pp. 3487-3496
-
-
Park, S.O.1
Wankhede, M.2
Lee, Y.J.3
Choi, E.J.4
Fliess, N.5
Choe, S.W.6
-
189
-
-
39849084288
-
Implications of mutations of activin receptor-like kinase 1 gene (ALK1) in addition to bone morphogenetic protein receptor II gene (BMPR2) in children with pulmonary arterial hypertension
-
Fujiwara M., Yagi H., Matsuoka R., Akimoto K., Furutani M., Imamura S., et al. Implications of mutations of activin receptor-like kinase 1 gene (ALK1) in addition to bone morphogenetic protein receptor II gene (BMPR2) in children with pulmonary arterial hypertension. Circ J 2008, 72:127-133.
-
(2008)
Circ J
, vol.72
, pp. 127-133
-
-
Fujiwara, M.1
Yagi, H.2
Matsuoka, R.3
Akimoto, K.4
Furutani, M.5
Imamura, S.6
-
190
-
-
0030050973
-
Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2
-
Johnson D.W., Berg J.N., Baldwin M.A., Gallione C.J., Marondel I., Yoon S.J., et al. Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet 1996, 13:189-195.
-
(1996)
Nat Genet
, vol.13
, pp. 189-195
-
-
Johnson, D.W.1
Berg, J.N.2
Baldwin, M.A.3
Gallione, C.J.4
Marondel, I.5
Yoon, S.J.6
-
191
-
-
53349108638
-
SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis
-
El-Bizri N., Guignabert C., Wang L., Cheng A., Stankunas K., Chang C.P., et al. SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. Development 2008, 135:2981-2991.
-
(2008)
Development
, vol.135
, pp. 2981-2991
-
-
El-Bizri, N.1
Guignabert, C.2
Wang, L.3
Cheng, A.4
Stankunas, K.5
Chang, C.P.6
-
192
-
-
0033888018
-
Endoglin expression is reduced in normal vessels but still detectable in arteriovenous malformations of patients with hereditary hemorrhagic telangiectasia type 1
-
Bourdeau A., Cymerman U., Paquet M.E., Meschino W., McKinnon W.C., Guttmacher A.E., et al. Endoglin expression is reduced in normal vessels but still detectable in arteriovenous malformations of patients with hereditary hemorrhagic telangiectasia type 1. Am J Pathol 2000, 156:911-923.
-
(2000)
Am J Pathol
, vol.156
, pp. 911-923
-
-
Bourdeau, A.1
Cymerman, U.2
Paquet, M.E.3
Meschino, W.4
McKinnon, W.C.5
Guttmacher, A.E.6
-
193
-
-
77952478858
-
Pathogenesis of arteriovenous malformations in the absence of endoglin
-
Mahmoud M., Allinson K.R., Zhai Z., Oakenfull R., Ghandi P., Adams R.H., et al. Pathogenesis of arteriovenous malformations in the absence of endoglin. Circ Res 2010, 106:1425-1433.
-
(2010)
Circ Res
, vol.106
, pp. 1425-1433
-
-
Mahmoud, M.1
Allinson, K.R.2
Zhai, Z.3
Oakenfull, R.4
Ghandi, P.5
Adams, R.H.6
-
194
-
-
33745318246
-
Distribution of ENG and ACVRL1 (ALK1) mutations in French HHT patients
-
Lesca G., Burnichon N., Raux G., Tosi M., Pinson S., Marion M.J., et al. Distribution of ENG and ACVRL1 (ALK1) mutations in French HHT patients. Hum Mutat 2006, 27(6):598.
-
(2006)
Hum Mutat
, vol.27
, Issue.6
, pp. 598
-
-
Lesca, G.1
Burnichon, N.2
Raux, G.3
Tosi, M.4
Pinson, S.5
Marion, M.J.6
-
195
-
-
75449083190
-
Overlapping spectra of SMAD4 mutations in juvenile polyposis (JP) and JP-HHT syndrome
-
A
-
Gallione C., Aylsworth A.S., Beis J., Berk T., Bernhardt B., Clark R.D., et al. Overlapping spectra of SMAD4 mutations in juvenile polyposis (JP) and JP-HHT syndrome. Am J Med Genet A 2010, 152A:333-339.
-
(2010)
Am J Med Genet A
, vol.152
, pp. 333-339
-
-
Gallione, C.1
Aylsworth, A.S.2
Beis, J.3
Berk, T.4
Bernhardt, B.5
Clark, R.D.6
-
196
-
-
33749260421
-
SMAD4 mutations found in unselected HHT patients
-
Gallione C.J., Richards J.A., Letteboer T.G., Rushlow D., Prigoda N.L., Leedom T.P., et al. SMAD4 mutations found in unselected HHT patients. J Med Genet 2006, 43:793-797.
-
(2006)
J Med Genet
, vol.43
, pp. 793-797
-
-
Gallione, C.J.1
Richards, J.A.2
Letteboer, T.G.3
Rushlow, D.4
Prigoda, N.L.5
Leedom, T.P.6
-
197
-
-
0036904895
-
Genetic analysis of the mammalian transforming growth factor-beta superfamily
-
Chang H., Brown C.W., Matzuk M.M. Genetic analysis of the mammalian transforming growth factor-beta superfamily. Endocr Rev 2002, 23:787-823.
-
(2002)
Endocr Rev
, vol.23
, pp. 787-823
-
-
Chang, H.1
Brown, C.W.2
Matzuk, M.M.3
-
198
-
-
34547781750
-
MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0
-
Tamura K., Dudley J., Nei M., Kumar S. MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 2007, 24:1596-1599.
-
(2007)
Mol Biol Evol
, vol.24
, pp. 1596-1599
-
-
Tamura, K.1
Dudley, J.2
Nei, M.3
Kumar, S.4
-
199
-
-
0023375195
-
The neighbor-joining method: a new method for reconstructing phylogenetic trees
-
Saitou N., Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 1987, 4:406-425.
-
(1987)
Mol Biol Evol
, vol.4
, pp. 406-425
-
-
Saitou, N.1
Nei, M.2
|