Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption

Nature

Volumn 434, Issue 7034, 2005, Pages 786-792

  Saadoun, Samira ^a   Papadopoulos, Marios C ^a   Hara Chikuma, Mariko ^a   Verkman, A S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BIOLOGICAL ORGANS; BLOOD VESSELS; GROWTH KINETICS; POLARIZATION; TUMORS;

CELL MIGRATION; ORGAN REGENERATION; WATER-SELECTIVE TRANS PORTER (AQP4); WOUND HEALING;

CELL CULTURE;

AQUAPORIN 1; AQP1 PROTEIN, MOUSE; AQP3 PROTEIN, MOUSE; AQP4 PROTEIN, MOUSE; AQUAPORIN; AQUAPORIN 3; AQUAPORIN 4; COLLAGEN; LAMININ; MATRIGEL; PROTEOGLYCAN; WATER;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE DISRUPTION; GENETIC TRANSFECTION; IN VITRO STUDY; MEMBRANE VESICLE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REGENERATION; TUMOR GROWTH; VASCULAR ENDOTHELIUM; WATER PERMEABILITY; WILD TYPE; WOUND HEALING; ANIMAL; CANCER TRANSPLANTATION; CELL CULTURE; CELL MOTION; CELL POLARITY; CYTOLOGY; DRUG COMBINATION; EXPERIMENTAL MELANOMA; GENE DELETION; GENETICS; METABOLISM; MOUSE MUTANT; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PSEUDOPODIUM;

ANIMALS; AQUAPORIN 1; AQUAPORIN 3; AQUAPORIN 4; AQUAPORINS; CELL ADHESION; CELL MOVEMENT; CELL POLARITY; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; DRUG COMBINATIONS; ENDOTHELIAL CELLS; GENE DELETION; LAMININ; MELANOMA, EXPERIMENTAL; MICE; MICE, KNOCKOUT; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PROTEOGLYCANS; PSEUDOPODIA; WATER; WOUND HEALING;

EID: 17144379334     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature03460     Document Type: Article

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