BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 287, Issue 6 31-6, 2004, Pages

  Beppu, Hideyuki ^a   Ichinose, Fumito ^a   Kawai, Noriko ^a   Jones, Rosemary C ^a   Yu, Paul B ^a   Zapol, Warren M ^a   Miyazono, Kohei ^b   Li, En ^a   Bloch, Kenneth D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CANCER INSTITUTE   (Japan)

Author keywords

Bone morphogenetic protein; Hypoxia; Pulmonary vasculature; Smooth muscle cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY; CONTROLLED STUDY; EXON; FEMALE; HEART VENTRICLE HYPERTROPHY; HEMODYNAMIC MONITORING; HEMOGLOBIN DETERMINATION; HISTOLOGY; HYPOXIA; LUNG; LUNG ALVEOLUS WALL; LUNG BLOOD VESSEL; LUNG VASCULAR RESISTANCE; MALE; MEAN ARTERIAL PRESSURE; MORPHOLOGY; MORPHOMETRICS; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SURGERY; WILD TYPE;

ANIMALS; ANOXIA; ARTERIOLES; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; EXONS; HETEROZYGOTE DETECTION; HYPERTENSION, PULMONARY; LUNG; MICE; MUTATION; PROTEIN-SERINE-THREONINE KINASES; PULMONARY CIRCULATION; SEQUENCE DELETION; VASCULAR RESISTANCE;

EID: 8644256840     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00239.2004     Document Type: Article

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