-
1
-
-
0034712047
-
Mammalian neural stem cells
-
1:CAS:528:DC%2BD3cXhsV2qtrg%3D 10688783
-
Gage FH (2000) Mammalian neural stem cells. Science 287(5457):1433-1438
-
(2000)
Science
, vol.287
, Issue.5457
, pp. 1433-1438
-
-
Gage, F.H.1
-
2
-
-
63849324022
-
Continuous neurogenesis in the adult brain
-
10.1111/j.1440-169X.2009.01094.x 19298551
-
Imayoshi I, Sakamoto M, Ohtsuka T, Kageyama R (2009) Continuous neurogenesis in the adult brain. Dev Growth Differ 51(3):379-386. doi: 10.1111/j.1440-169X.2009.01094.x
-
(2009)
Dev Growth Differ
, vol.51
, Issue.3
, pp. 379-386
-
-
Imayoshi, I.1
Sakamoto, M.2
Ohtsuka, T.3
Kageyama, R.4
-
3
-
-
52949147794
-
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain
-
10.1038/nn.2185 1:CAS:528:DC%2BD1cXhtFKhsL%2FJ 18758458
-
Imayoshi I, Sakamoto M, Ohtsuka T, Takao K, Miyakawa T, Yamaguchi M, Mori K, Ikeda T, Itohara S, Kageyama R (2008) Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat Neurosci 11(10):1153-1161. doi: 10.1038/nn.2185
-
(2008)
Nat Neurosci
, vol.11
, Issue.10
, pp. 1153-1161
-
-
Imayoshi, I.1
Sakamoto, M.2
Ohtsuka, T.3
Takao, K.4
Miyakawa, T.5
Yamaguchi, M.6
Mori, K.7
Ikeda, T.8
Itohara, S.9
Kageyama, R.10
-
4
-
-
67651036549
-
The glial nature of embryonic and adult neural stem cells
-
10.1146/annurev.neuro.051508.135600 1:CAS:528:DC%2BD1MXpsV2nurk%3D 19555289
-
Kriegstein A, Alvarez-Buylla A (2009) The glial nature of embryonic and adult neural stem cells. Annu Rev Neurosci 32:149-184. doi: 10.1146/annurev. neuro.051508.135600
-
(2009)
Annu Rev Neurosci
, vol.32
, pp. 149-184
-
-
Kriegstein, A.1
Alvarez-Buylla, A.2
-
5
-
-
23244458855
-
Adult neurogenesis in the mammalian central nervous system
-
10.1146/annurev.neuro.28.051804.101459 1:CAS:528:DC%2BD2MXosVegtLs%3D 16022595
-
Ming GL, Song H (2005) Adult neurogenesis in the mammalian central nervous system. Annu Rev Neurosci 28:223-250. doi: 10.1146/annurev.neuro.28. 051804.101459
-
(2005)
Annu Rev Neurosci
, vol.28
, pp. 223-250
-
-
Ming, G.L.1
Song, H.2
-
6
-
-
0035499887
-
The development of neural stem cells
-
10.1038/35102174 1:CAS:528:DC%2BD3MXot1ahu7c%3D 11689956
-
Temple S (2001) The development of neural stem cells. Nature 414(6859):112-117. doi: 10.1038/35102174
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 112-117
-
-
Temple, S.1
-
7
-
-
24344510750
-
The cell biology of neurogenesis
-
10.1038/nrm1739 16314867
-
Gotz M, Huttner WB (2005) The cell biology of neurogenesis. Nat Rev Mol Cell Biol 6(10):777-788. doi: 10.1038/nrm1739
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.10
, pp. 777-788
-
-
Gotz, M.1
Huttner, W.B.2
-
8
-
-
77953625257
-
Cdks and cyclins link G1 length and differentiation of embryonic, neural and hematopoietic stem cells
-
1:CAS:528:DC%2BC3cXht12ktbfP 20436288
-
Lange C, Calegari F (2010) Cdks and cyclins link G1 length and differentiation of embryonic, neural and hematopoietic stem cells. Cell Cycle 9(10):1893-1900
-
(2010)
Cell Cycle
, vol.9
, Issue.10
, pp. 1893-1900
-
-
Lange, C.1
Calegari, F.2
-
9
-
-
69249213590
-
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors
-
10.1016/j.stem.2009.05.026 1:CAS:528:DC%2BD1MXhsVCiurbE 19733543
-
Lange C, Huttner WB, Calegari F (2009) Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. Cell Stem Cell 5(3):320-331. doi: 10.1016/j.stem.2009.05.026
-
(2009)
Cell Stem Cell
, vol.5
, Issue.3
, pp. 320-331
-
-
Lange, C.1
Huttner, W.B.2
Calegari, F.3
-
10
-
-
66049106738
-
Home at last: Neural stem cell niches defined
-
10.1016/j.stem.2009.05.008 1:CAS:528:DC%2BD1MXnt1GgtL0%3D 19497279
-
Miller FD, Gauthier-Fisher A (2009) Home at last: neural stem cell niches defined. Cell Stem Cell 4(6):507-510. doi: 10.1016/j.stem.2009.05.008
-
(2009)
Cell Stem Cell
, vol.4
, Issue.6
, pp. 507-510
-
-
Miller, F.D.1
Gauthier-Fisher, A.2
-
11
-
-
77952544890
-
Cell cycle control of mammalian neural stem cells: Putting a speed limit on G1
-
10.1016/j.tcb.2010.01.006 1:CAS:528:DC%2BC3cXlsFWqu7k%3D 20153966
-
Salomoni P, Calegari F (2010) Cell cycle control of mammalian neural stem cells: putting a speed limit on G1. Trends Cell Biol 20(5):233-243. doi: 10.1016/j.tcb.2010.01.006
-
(2010)
Trends Cell Biol
, vol.20
, Issue.5
, pp. 233-243
-
-
Salomoni, P.1
Calegari, F.2
-
12
-
-
0030987612
-
Genetic influence on neurogenesis in the dentate gyrus of adult mice
-
1:CAS:528:DyaK2sXmt1Gjtrs%3D 9294224
-
Kempermann G, Kuhn HG, Gage FH (1997) Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proc Natl Acad Sci USA 94(19):10409-10414
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.19
, pp. 10409-10414
-
-
Kempermann, G.1
Kuhn, H.G.2
Gage, F.H.3
-
13
-
-
0026535505
-
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
-
1:STN:280:DyaK383gsFemsw%3D%3D 1553558
-
Reynolds BA, Weiss S (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255(5052):1707-1710
-
(1992)
Science
, vol.255
, Issue.5052
, pp. 1707-1710
-
-
Reynolds, B.A.1
Weiss, S.2
-
14
-
-
0026688533
-
De novo generation of neuronal cells from the adult mouse brain
-
1:CAS:528:DyaK3sXhvF2huw%3D%3D 1528866
-
Richards LJ, Kilpatrick TJ, Bartlett PF (1992) De novo generation of neuronal cells from the adult mouse brain. Proc Natl Acad Sci USA 89(18):8591-8595
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, Issue.18
, pp. 8591-8595
-
-
Richards, L.J.1
Kilpatrick, T.J.2
Bartlett, P.F.3
-
15
-
-
22844437215
-
Isolation of neural stem cells from the postnatal cerebellum
-
10.1038/nn1473 1:CAS:528:DC%2BD2MXksVeit7c%3D 15908947
-
Lee A, Kessler JD, Read TA, Kaiser C, Corbeil D, Huttner WB, Johnson JE, Wechsler-Reya RJ (2005) Isolation of neural stem cells from the postnatal cerebellum. Nat Neurosci 8(6):723-729. doi: 10.1038/nn1473
-
(2005)
Nat Neurosci
, vol.8
, Issue.6
, pp. 723-729
-
-
Lee, A.1
Kessler, J.D.2
Read, T.A.3
Kaiser, C.4
Corbeil, D.5
Huttner, W.B.6
Johnson, J.E.7
Wechsler-Reya, R.J.8
-
16
-
-
0036703488
-
The adult substantia nigra contains progenitor cells with neurogenic potential
-
20026700 1:CAS:528:DC%2BD38XlvFKntrs%3D 12151543
-
Lie DC, Dziewczapolski G, Willhoite AR, Kaspar BK, Shults CW, Gage FH (2002) The adult substantia nigra contains progenitor cells with neurogenic potential. J Neurosci 22(15):6639-6649. doi: 20026700
-
(2002)
J Neurosci
, vol.22
, Issue.15
, pp. 6639-6649
-
-
Lie, D.C.1
Dziewczapolski, G.2
Willhoite, A.R.3
Kaspar, B.K.4
Shults, C.W.5
Gage, F.H.6
-
17
-
-
0038037721
-
Evidence for neurogenesis in the adult mammalian substantia nigra
-
10.1073/pnas.1131955100 1:CAS:528:DC%2BD3sXlt1WqtrY%3D 12792021
-
Zhao M, Momma S, Delfani K, Carlen M, Cassidy RM, Johansson CB, Brismar H, Shupliakov O, Frisen J, Janson AM (2003) Evidence for neurogenesis in the adult mammalian substantia nigra. Proc Natl Acad Sci USA 100(13):7925-7930. doi: 10.1073/pnas.1131955100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.13
, pp. 7925-7930
-
-
Zhao, M.1
Momma, S.2
Delfani, K.3
Carlen, M.4
Cassidy, R.M.5
Johansson, C.B.6
Brismar, H.7
Shupliakov, O.8
Frisen, J.9
Janson, A.M.10
-
18
-
-
11144305844
-
Retinal stem cells in vertebrates: Parallels and divergences
-
10.1387/ijdb.041879ma 15558490
-
Amato MA, Arnault E, Perron M (2004) Retinal stem cells in vertebrates: parallels and divergences. Int J Dev Biol 48(8-9):993-1001. doi: 10.1387/ijdb.041879ma
-
(2004)
Int J Dev Biol
, vol.48
, Issue.8-9
, pp. 993-1001
-
-
Amato, M.A.1
Arnault, E.2
Perron, M.3
-
19
-
-
33748630498
-
Molecular characterization of retinal stem cells and their niches in adult zebrafish
-
10.1186/1471-213X-6-36 16872490
-
Raymond PA, Barthel LK, Bernardos RL, Perkowski JJ (2006) Molecular characterization of retinal stem cells and their niches in adult zebrafish. BMC Dev Biol 6:36. doi: 10.1186/1471-213X-6-36
-
(2006)
BMC Dev Biol
, vol.6
, pp. 36
-
-
Raymond, P.A.1
Barthel, L.K.2
Bernardos, R.L.3
Perkowski, J.J.4
-
20
-
-
70350220586
-
Mechanisms of stem cell self-renewal
-
10.1146/annurev.cellbio.042308.113248 1:CAS:528:DC%2BD1MXhsVKisbvJ 19575646
-
He S, Nakada D, Morrison SJ (2009) Mechanisms of stem cell self-renewal. Annu Rev Cell Dev Biol 25:377-406. doi: 10.1146/annurev.cellbio.042308.113248
-
(2009)
Annu Rev Cell Dev Biol
, vol.25
, pp. 377-406
-
-
He, S.1
Nakada, D.2
Morrison, S.J.3
-
21
-
-
77249176666
-
P53 and stem cells: New developments and new concerns
-
10.1016/j.tcb.2009.12.004 1:CAS:528:DC%2BC3cXisFemu7o%3D 20061153
-
Zhao T, Xu Y (2010) p53 and stem cells: new developments and new concerns. Trends Cell Biol 20(3):170-175. doi: 10.1016/j.tcb.2009.12.004
-
(2010)
Trends Cell Biol
, vol.20
, Issue.3
, pp. 170-175
-
-
Zhao, T.1
Xu, Y.2
-
22
-
-
33747608668
-
DNA damage response and mutagenesis in mouse embryonic stem cells
-
10.1385/1-59745-037-5:313 1:CAS:528:DC%2BD28XislKhs7o%3D 16846001
-
Hong Y, Cervantes RB, Stambrook PJ (2006) DNA damage response and mutagenesis in mouse embryonic stem cells. Methods Mol Biol 329:313-326. doi: 10.1385/1-59745-037-5:313
-
(2006)
Methods Mol Biol
, vol.329
, pp. 313-326
-
-
Hong, Y.1
Cervantes, R.B.2
Stambrook, P.J.3
-
23
-
-
33845411722
-
Protecting genomic integrity in somatic cells and embryonic stem cells
-
10.1016/j.mrfmmm.2006.06.006 1:CAS:528:DC%2BD28Xhtlaqs7nF 16914171
-
Hong Y, Cervantes RB, Tichy E, Tischfield JA, Stambrook PJ (2007) Protecting genomic integrity in somatic cells and embryonic stem cells. Mutat Res 614(1-2):48-55. doi: 10.1016/j.mrfmmm.2006.06.006
-
(2007)
Mutat Res
, vol.614
, Issue.1-2
, pp. 48-55
-
-
Hong, Y.1
Cervantes, R.B.2
Tichy, E.3
Tischfield, J.A.4
Stambrook, P.J.5
-
24
-
-
14644411092
-
Stem cell: Balancing aging and cancer
-
10.1016/j.biocel.2004.10.007 1:CAS:528:DC%2BD2MXhvVGjs70%3D 15743668
-
Krtolica A (2005) Stem cell: balancing aging and cancer. Int J Biochem Cell Biol 37(5):935-941. doi: 10.1016/j.biocel.2004.10.007
-
(2005)
Int J Biochem Cell Biol
, vol.37
, Issue.5
, pp. 935-941
-
-
Krtolica, A.1
-
25
-
-
0034881127
-
Cyclin-dependent kinase inhibitors in the development of the central nervous system
-
1:CAS:528:DC%2BD3MXmsFGqurY%3D 11504704
-
Cunningham JJ, Roussel MF (2001) Cyclin-dependent kinase inhibitors in the development of the central nervous system. Cell Growth Differ 12(8):387-396
-
(2001)
Cell Growth Differ
, vol.12
, Issue.8
, pp. 387-396
-
-
Cunningham, J.J.1
Roussel, M.F.2
-
26
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
1:CAS:528:DyaK1MXjvFOju78%3D 10380923
-
Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97(6):703-716
-
(1999)
Cell
, vol.97
, Issue.6
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
27
-
-
0037137686
-
EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells
-
1:CAS:528:DC%2BD3sXhtVOhuw%3D%3D 12495619
-
Doetsch F, Petreanu L, Caille I, Garcia-Verdugo JM, Alvarez-Buylla A (2002) EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron 36(6):1021-1034
-
(2002)
Neuron
, vol.36
, Issue.6
, pp. 1021-1034
-
-
Doetsch, F.1
Petreanu, L.2
Caille, I.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
28
-
-
79956209852
-
Adult neurogenesis in the mammalian brain: Significant answers and significant questions
-
10.1016/j.neuron.2011.05.001 1:CAS:528:DC%2BC3MXmvVehtLk%3D 21609825
-
Ming GL, Song H (2011) Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70(4):687-702. doi: 10.1016/j.neuron.2011.05.001
-
(2011)
Neuron
, vol.70
, Issue.4
, pp. 687-702
-
-
Ming, G.L.1
Song, H.2
-
29
-
-
1542268981
-
For the long run: Maintaining germinal niches in the adult brain
-
1:CAS:528:DC%2BD2cXisVKitLY%3D 15003168
-
Alvarez-Buylla A, Lim DA (2004) For the long run: maintaining germinal niches in the adult brain. Neuron 41(5):683-686
-
(2004)
Neuron
, vol.41
, Issue.5
, pp. 683-686
-
-
Alvarez-Buylla, A.1
Lim, D.A.2
-
30
-
-
50849113768
-
Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain
-
10.1016/j.stem.2008.07.004 1:CAS:528:DC%2BD1cXhtF2jtr7F 18786414
-
Mirzadeh Z, Merkle FT, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla A (2008) Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 3(3):265-278. doi: 10.1016/j.stem.2008.07.004
-
(2008)
Cell Stem Cell
, vol.3
, Issue.3
, pp. 265-278
-
-
Mirzadeh, Z.1
Merkle, F.T.2
Soriano-Navarro, M.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
31
-
-
50849142558
-
Adult SVZ stem cells lie in a vascular niche: A quantitative analysis of niche cell-cell interactions
-
10.1016/j.stem.2008.07.026 1:CAS:528:DC%2BD1cXhtF2jtr%2FN 18786416
-
Shen Q, Wang Y, Kokovay E, Lin G, Chuang SM, Goderie SK, Roysam B, Temple S (2008) Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 3(3):289-300. doi: 10.1016/j.stem.2008.07.026
-
(2008)
Cell Stem Cell
, vol.3
, Issue.3
, pp. 289-300
-
-
Shen, Q.1
Wang, Y.2
Kokovay, E.3
Lin, G.4
Chuang, S.M.5
Goderie, S.K.6
Roysam, B.7
Temple, S.8
-
32
-
-
50849102656
-
A specialized vascular niche for adult neural stem cells
-
10.1016/j.stem.2008.07.025 1:CAS:528:DC%2BD1cXhtF2jtr%2FM 18786415
-
Tavazoie M, Van der Veken L, Silva-Vargas V, Louissaint M, Colonna L, Zaidi B, Garcia-Verdugo JM, Doetsch F (2008) A specialized vascular niche for adult neural stem cells. Cell Stem Cell 3(3):279-288. doi: 10.1016/j.stem.2008. 07.025
-
(2008)
Cell Stem Cell
, vol.3
, Issue.3
, pp. 279-288
-
-
Tavazoie, M.1
Van Der Veken, L.2
Silva-Vargas, V.3
Louissaint, M.4
Colonna, L.5
Zaidi, B.6
Garcia-Verdugo, J.M.7
Doetsch, F.8
-
33
-
-
0242321829
-
The glial identity of neural stem cells
-
10.1038/nn1144 1:CAS:528:DC%2BD3sXosVOiu7g%3D 14583753
-
Doetsch F (2003) The glial identity of neural stem cells. Nat Neurosci 6(11):1127-1134. doi: 10.1038/nn1144
-
(2003)
Nat Neurosci
, vol.6
, Issue.11
, pp. 1127-1134
-
-
Doetsch, F.1
-
34
-
-
27544470656
-
Mammalian cyclin-dependent kinases
-
10.1016/j.tibs.2005.09.005 1:CAS:528:DC%2BD2MXhtFKhsLvE 16236519
-
Malumbres M, Barbacid M (2005) Mammalian cyclin-dependent kinases. Trends Biochem Sci 30(11):630-641. doi: 10.1016/j.tibs.2005.09.005
-
(2005)
Trends Biochem Sci
, vol.30
, Issue.11
, pp. 630-641
-
-
Malumbres, M.1
Barbacid, M.2
-
35
-
-
0029984015
-
Regulating S phase: CDKs, licensing and proteolysis
-
1:CAS:528:DyaK28XjslSkur0%3D 8681373
-
Wuarin J, Nurse P (1996) Regulating S phase: CDKs, licensing and proteolysis. Cell 85(6):785-787
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 785-787
-
-
Wuarin, J.1
Nurse, P.2
-
36
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
1:CAS:528:DyaK1MXktlOhsLs%3D 10385618
-
Sherr CJ, Roberts JM (1999) CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13(12):1501-1512
-
(1999)
Genes Dev
, vol.13
, Issue.12
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
37
-
-
38849187293
-
CDK inhibitors: Cell cycle regulators and beyond
-
10.1016/j.devcel.2008.01.013 1:CAS:528:DC%2BD1cXit1Ojsrc%3D 18267085
-
Besson A, Dowdy SF, Roberts JM (2008) CDK inhibitors: cell cycle regulators and beyond. Dev Cell 14(2):159-169. doi: 10.1016/j.devcel.2008.01.013
-
(2008)
Dev Cell
, vol.14
, Issue.2
, pp. 159-169
-
-
Besson, A.1
Dowdy, S.F.2
Roberts, J.M.3
-
38
-
-
27144458683
-
Cyclins and CDKS in development and cancer: Lessons from genetically modified mice
-
1:CAS:528:DC%2BD2MXhtlSru77I 16146805
-
Santamaria D, Ortega S (2006) Cyclins and CDKS in development and cancer: lessons from genetically modified mice. Front Biosci 11:1164-1188
-
(2006)
Front Biosci
, vol.11
, pp. 1164-1188
-
-
Santamaria, D.1
Ortega, S.2
-
39
-
-
0037320701
-
Induction and patterning of neuronal development, and its connection to cell cycle control
-
1:CAS:528:DC%2BD3sXht1Krt74%3D 12593978
-
Bally-Cuif L, Hammerschmidt M (2003) Induction and patterning of neuronal development, and its connection to cell cycle control. Curr Opin Neurobiol 13(1):16-25
-
(2003)
Curr Opin Neurobiol
, vol.13
, Issue.1
, pp. 16-25
-
-
Bally-Cuif, L.1
Hammerschmidt, M.2
-
40
-
-
34249004934
-
Cell-cycle control and cortical development
-
10.1038/nrn2097 1:CAS:528:DC%2BD2sXlsVSktLk%3D 17514197
-
Dehay C, Kennedy H (2007) Cell-cycle control and cortical development. Nat Rev Neurosci 8(6):438-450. doi: 10.1038/nrn2097
-
(2007)
Nat Rev Neurosci
, vol.8
, Issue.6
, pp. 438-450
-
-
Dehay, C.1
Kennedy, H.2
-
41
-
-
0033957316
-
A cell-intrinsic timer that operates during oligodendrocyte development
-
10.1002/(SICI)1521-1878(200001)22:1<64: AID-BIES11>3.0.CO;2-Q 1:CAS:528:DC%2BD3MXmslGrsLo%3D 10649292
-
Durand B, Raff M (2000) A cell-intrinsic timer that operates during oligodendrocyte development. BioEssays 22(1):64-71. doi: 10.1002/(SICI)1521- 1878(200001)22:1<64:AID-BIES11>3.0.CO;2-Q
-
(2000)
BioEssays
, vol.22
, Issue.1
, pp. 64-71
-
-
Durand, B.1
Raff, M.2
-
42
-
-
0036813521
-
Cyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors
-
1:CAS:528:DC%2BD38Xns1Cisro%3D 12351729
-
Belachew S, Aguirre AA, Wang H, Vautier F, Yuan X, Anderson S, Kirby M, Gallo V (2002) Cyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors. J Neurosci 22(19):8553-8562
-
(2002)
J Neurosci
, vol.22
, Issue.19
, pp. 8553-8562
-
-
Belachew, S.1
Aguirre, A.A.2
Wang, H.3
Vautier, F.4
Yuan, X.5
Anderson, S.6
Kirby, M.7
Gallo, V.8
-
43
-
-
0034721938
-
The Rb-CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation
-
10.1074/jbc.M004879200 1:CAS:528:DC%2BD3cXnvVyjsL4%3D 10915795
-
Ferguson KL, Callaghan SM, O'Hare MJ, Park DS, Slack RS (2000) The Rb-CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation. J Biol Chem 275(43):33593-33600. doi: 10.1074/jbc.M004879200
-
(2000)
J Biol Chem
, vol.275
, Issue.43
, pp. 33593-33600
-
-
Ferguson, K.L.1
Callaghan, S.M.2
O'Hare, M.J.3
Park, D.S.4
Slack, R.S.5
-
44
-
-
38149010217
-
CDK2 is dispensable for adult hippocampal neurogenesis
-
1:CAS:528:DC%2BD1cXit1ShtLo%3D 18073538
-
Vandenbosch R, Borgs L, Beukelaers P, Foidart A, Nguyen L, Moonen G, Berthet C, Kaldis P, Gallo V, Belachew S, Malgrange B (2007) CDK2 is dispensable for adult hippocampal neurogenesis. Cell Cycle 6(24):3065-3069
-
(2007)
Cell Cycle
, vol.6
, Issue.24
, pp. 3065-3069
-
-
Vandenbosch, R.1
Borgs, L.2
Beukelaers, P.3
Foidart, A.4
Nguyen, L.5
Moonen, G.6
Berthet, C.7
Kaldis, P.8
Gallo, V.9
Belachew, S.10
Malgrange, B.11
-
45
-
-
79956125698
-
Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain
-
10.1084/jem.20102167 1:CAS:528:DC%2BC3MXmt1WrsLo%3D 21482697
-
Artegiani B, Lindemann D, Calegari F (2011) Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain. J Exp Med 208(5):937-948. doi: 10.1084/jem.20102167
-
(2011)
J Exp Med
, vol.208
, Issue.5
, pp. 937-948
-
-
Artegiani, B.1
Lindemann, D.2
Calegari, F.3
-
46
-
-
79953794428
-
Cdk6-dependent regulation of G(1) length controls adult neurogenesis
-
10.1002/stem.616 1:CAS:528:DC%2BC3MXmslels7k%3D 21319271
-
Beukelaers P, Vandenbosch R, Caron N, Nguyen L, Belachew S, Moonen G, Kiyokawa H, Barbacid M, Santamaria D, Malgrange B (2011) Cdk6-dependent regulation of G(1) length controls adult neurogenesis. Stem Cells 29(4):713-724. doi: 10.1002/stem.616
-
(2011)
Stem Cells
, vol.29
, Issue.4
, pp. 713-724
-
-
Beukelaers, P.1
Vandenbosch, R.2
Caron, N.3
Nguyen, L.4
Belachew, S.5
Moonen, G.6
Kiyokawa, H.7
Barbacid, M.8
Santamaria, D.9
Malgrange, B.10
-
47
-
-
0018348655
-
T antigen is bound to a host protein in SV40-transformed cells
-
1:CAS:528:DyaE1MXkvV2gtr0%3D 218111
-
Lane DP, Crawford LV (1979) T antigen is bound to a host protein in SV40-transformed cells. Nature 278(5701):261-263
-
(1979)
Nature
, vol.278
, Issue.5701
, pp. 261-263
-
-
Lane, D.P.1
Crawford, L.V.2
-
48
-
-
0018616778
-
The SV40 A gene product is required for the production of a 54,000 MW cellular tumor antigen
-
1:CAS:528:DyaE1MXmtVOhsbg%3D 228475
-
Linzer DI, Maltzman W, Levine AJ (1979) The SV40 A gene product is required for the production of a 54,000 MW cellular tumor antigen. Virology 98(2):308-318
-
(1979)
Virology
, vol.98
, Issue.2
, pp. 308-318
-
-
Linzer, D.I.1
Maltzman, W.2
Levine, A.J.3
-
49
-
-
0032475878
-
Signaling to p53: Breaking the MDM2-p53 circuit
-
1:CAS:528:DyaK1cXmslWmu7k%3D 9778240
-
Prives C (1998) Signaling to p53: breaking the MDM2-p53 circuit. Cell 95(1):5-8
-
(1998)
Cell
, vol.95
, Issue.1
, pp. 5-8
-
-
Prives, C.1
-
50
-
-
0033028043
-
The role of p53 in tumour suppression: Lessons from mouse models
-
1:CAS:528:DyaK1MXhtV2lsLo%3D 10065151
-
Attardi LD, Jacks T (1999) The role of p53 in tumour suppression: lessons from mouse models. Cell Mol Life Sci 55(1):48-63
-
(1999)
Cell Mol Life Sci
, vol.55
, Issue.1
, pp. 48-63
-
-
Attardi, L.D.1
Jacks, T.2
-
51
-
-
0022646788
-
Localization of gene for human p53 tumour antigen to band 17p13
-
10.1038/320084a0 1:CAS:528:DyaL28Xhs1Kms7o%3D 3456488
-
Isobe M, Emanuel BS, Givol D, Oren M, Croce CM (1986) Localization of gene for human p53 tumour antigen to band 17p13. Nature 320(6057):84-85. doi: 10.1038/320084a0
-
(1986)
Nature
, vol.320
, Issue.6057
, pp. 84-85
-
-
Isobe, M.1
Emanuel, B.S.2
Givol, D.3
Oren, M.4
Croce, C.M.5
-
52
-
-
0029967219
-
Lessons from the p53 mutant mouse
-
1:CAS:528:DyaK28Xkt1aqsro%3D 8642041
-
Jacks T (1996) Lessons from the p53 mutant mouse. J Cancer Res Clin Oncol 122(6):319-327
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, Issue.6
, pp. 319-327
-
-
Jacks, T.1
-
53
-
-
0025815451
-
Identification of p53 as a sequence-specific DNA-binding protein
-
1:CAS:528:DyaK3MXkvVKmurs%3D 2047879
-
Kern SE, Kinzler KW, Bruskin A, Jarosz D, Friedman P, Prives C, Vogelstein B (1991) Identification of p53 as a sequence-specific DNA-binding protein. Science 252(5013):1708-1711
-
(1991)
Science
, vol.252
, Issue.5013
, pp. 1708-1711
-
-
Kern, S.E.1
Kinzler, K.W.2
Bruskin, A.3
Jarosz, D.4
Friedman, P.5
Prives, C.6
Vogelstein, B.7
-
54
-
-
0021767927
-
Isolation and characterization of a human p53 cDNA clone: Expression of the human p53 gene
-
1:CAS:528:DyaL2MXhtVOgs7c%3D 6396087
-
Matlashewski G, Lamb P, Pim D, Peacock J, Crawford L, Benchimol S (1984) Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene. EMBO J 3(13):3257-3262
-
(1984)
EMBO J
, vol.3
, Issue.13
, pp. 3257-3262
-
-
Matlashewski, G.1
Lamb, P.2
Pim, D.3
Peacock, J.4
Crawford, L.5
Benchimol, S.6
-
55
-
-
0344246051
-
The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13)
-
1:CAS:528:DyaL28Xot12qsw%3D%3D 3001719
-
McBride OW, Merry D, Givol D (1986) The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13). Proc Natl Acad Sci USA 83(1):130-134
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, Issue.1
, pp. 130-134
-
-
McBride, O.W.1
Merry, D.2
Givol, D.3
-
56
-
-
42449114966
-
Transcriptional control of human p53-regulated genes
-
10.1038/nrm2395 1:CAS:528:DC%2BD1cXkvF2gtL8%3D 18431400
-
Riley T, Sontag E, Chen P, Levine A (2008) Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 9(5):402-412. doi: 10.1038/nrm2395
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.5
, pp. 402-412
-
-
Riley, T.1
Sontag, E.2
Chen, P.3
Levine, A.4
-
57
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
10.1038/nature07986 1:CAS:528:DC%2BD1MXlt1Srt7Y%3D 19407794
-
Green DR, Kroemer G (2009) Cytoplasmic functions of the tumour suppressor p53. Nature 458(7242):1127-1130. doi: 10.1038/nature07986
-
(2009)
Nature
, vol.458
, Issue.7242
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
58
-
-
77955827519
-
The origins and evolution of the p53 family of genes
-
10.1101/cshperspect.a001198 20516129
-
Belyi VA, Ak P, Markert E, Wang H, Hu W, Puzio-Kuter A, Levine AJ (2010) The origins and evolution of the p53 family of genes. Cold Spring Harb Perspect Biol 2(6):a001198. doi: 10.1101/cshperspect.a001198
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.6
, pp. 001198
-
-
Belyi, V.A.1
Ak, P.2
Markert, E.3
Wang, H.4
Hu, W.5
Puzio-Kuter, A.6
Levine, A.J.7
-
59
-
-
78650316134
-
P53 Research: The past thirty years and the next thirty years
-
10.1101/cshperspect.a000893 1:CAS:528:DC%2BC3MXhsFKqt7s%3D 20463001
-
Lane D, Levine A (2010) p53 Research: the past thirty years and the next thirty years. Cold Spring Harb Perspect Biol 2(12):a000893. doi: 10.1101/cshperspect.a000893
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.12
, pp. 000893
-
-
Lane, D.1
Levine, A.2
-
60
-
-
24944495794
-
P53: Link to the past, bridge to the future
-
10.1101/gad.1362905 1:CAS:528:DC%2BD2MXhtVGlsr%2FF 16166374
-
Mills AA (2005) p53: link to the past, bridge to the future. Genes Dev 19(18):2091-2099. doi: 10.1101/gad.1362905
-
(2005)
Genes Dev
, vol.19
, Issue.18
, pp. 2091-2099
-
-
Mills, A.A.1
-
61
-
-
70349459599
-
P53 and metabolism
-
10.1038/nrc2715 1:CAS:528:DC%2BD1MXhtFentb%2FM 19759539
-
Vousden KH, Ryan KM (2009) p53 and metabolism. Nat Rev Cancer 9(10):691-700. doi: 10.1038/nrc2715
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.10
, pp. 691-700
-
-
Vousden, K.H.1
Ryan, K.M.2
-
62
-
-
77951243028
-
Autophagy regulation by p53
-
10.1016/j.ceb.2009.12.001 1:CAS:528:DC%2BC3cXks1Srtbo%3D 20044243
-
Maiuri MC, Galluzzi L, Morselli E, Kepp O, Malik SA, Kroemer G (2010) Autophagy regulation by p53. Curr Opin Cell Biol 22(2):181-185. doi: 10.1016/j.ceb.2009.12.001
-
(2010)
Curr Opin Cell Biol
, vol.22
, Issue.2
, pp. 181-185
-
-
Maiuri, M.C.1
Galluzzi, L.2
Morselli, E.3
Kepp, O.4
Malik, S.A.5
Kroemer, G.6
-
63
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
10.1016/j.cell.2006.05.034 1:CAS:528:DC%2BD28Xns1Cgt7w%3D 16839881
-
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 126(1):121-134. doi: 10.1016/j.cell.2006.05.034
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
Gasco, M.7
Garrone, O.8
Crook, T.9
Ryan, K.M.10
-
64
-
-
0033781632
-
Neuronal life and death: An essential role for the p53 family
-
10.1038/sj.cdd.4400736 1:CAS:528:DC%2BD3cXnslWjtbY%3D 11279533
-
Miller FD, Pozniak CD, Walsh GS (2000) Neuronal life and death: an essential role for the p53 family. Cell Death Differ 7(10):880-888. doi: 10.1038/sj.cdd.4400736
-
(2000)
Cell Death Differ
, vol.7
, Issue.10
, pp. 880-888
-
-
Miller, F.D.1
Pozniak, C.D.2
Walsh, G.S.3
-
65
-
-
32244436592
-
P53 suppresses the self-renewal of adult neural stem cells
-
10.1242/dev.02208 1:CAS:528:DC%2BD28XhsFamsrk%3D 16368933
-
Meletis K, Wirta V, Hede SM, Nister M, Lundeberg J, Frisen J (2006) p53 suppresses the self-renewal of adult neural stem cells. Development 133(2):363-369. doi: 10.1242/dev.02208
-
(2006)
Development
, vol.133
, Issue.2
, pp. 363-369
-
-
Meletis, K.1
Wirta, V.2
Hede, S.M.3
Nister, M.4
Lundeberg, J.5
Frisen, J.6
-
66
-
-
0032572566
-
Tumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain: Comparison with expression of the cell cycle regulators p21Waf1/Cip1, p27Kip1, p57Kip2, p16Ink4a, cyclin G1, and the proto-oncogene Bax
-
van Lookeren Campagne M, Gill R (1998) Tumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain: comparison with expression of the cell cycle regulators p21Waf1/Cip1, p27Kip1, p57Kip2, p16Ink4a, cyclin G1, and the proto-oncogene Bax. J Comp Neurol 397(2):181-198
-
(1998)
J Comp Neurol
, vol.397
, Issue.2
, pp. 181-198
-
-
Van Lookeren, C.M.1
Gill, R.2
-
67
-
-
0033562491
-
P53 expression and regulation by NMDA receptors in the developing rat brain
-
1:CAS:528:DyaK1MXjtVansL8%3D 10340750
-
Poulaki V, Benekou A, Bozas E, Bolaris S, Stylianopoulou F (1999) p53 expression and regulation by NMDA receptors in the developing rat brain. J Neurosci Res 56(4):427-440
-
(1999)
J Neurosci Res
, vol.56
, Issue.4
, pp. 427-440
-
-
Poulaki, V.1
Benekou, A.2
Bozas, E.3
Bolaris, S.4
Stylianopoulou, F.5
-
68
-
-
79955428953
-
P53 coordinates cranial neural crest cell growth and epithelial- mesenchymal transition/delamination processes
-
10.1242/dev.053645 1:CAS:528:DC%2BC3MXnt1eqtLc%3D 21447558
-
Rinon A, Molchadsky A, Nathan E, Yovel G, Rotter V, Sarig R, Tzahor E (2011) p53 coordinates cranial neural crest cell growth and epithelial- mesenchymal transition/delamination processes. Development 138(9):1827-1838. doi: 10.1242/dev.053645
-
(2011)
Development
, vol.138
, Issue.9
, pp. 1827-1838
-
-
Rinon, A.1
Molchadsky, A.2
Nathan, E.3
Yovel, G.4
Rotter, V.5
Sarig, R.6
Tzahor, E.7
-
69
-
-
0029347164
-
High-frequency developmental abnormalities in p53-deficient mice
-
1:CAS:528:DyaK2MXnsVCis78%3D 7583151
-
Armstrong JF, Kaufman MH, Harrison DJ, Clarke AR (1995) High-frequency developmental abnormalities in p53-deficient mice. Curr Biol 5(8):931-936
-
(1995)
Curr Biol
, vol.5
, Issue.8
, pp. 931-936
-
-
Armstrong, J.F.1
Kaufman, M.H.2
Harrison, D.J.3
Clarke, A.R.4
-
70
-
-
0029007405
-
A subset of p53-deficient embryos exhibit exencephaly
-
10.1038/ng0695-175 1:CAS:528:DyaK2MXmtFCqtrc%3D 7663512
-
Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T (1995) A subset of p53-deficient embryos exhibit exencephaly. Nat Genet 10(2):175-180. doi: 10.1038/ng0695-175
-
(1995)
Nat Genet
, vol.10
, Issue.2
, pp. 175-180
-
-
Sah, V.P.1
Attardi, L.D.2
Mulligan, G.J.3
Williams, B.O.4
Bronson, R.T.5
Jacks, T.6
-
71
-
-
0034517534
-
Evolution of functions within the p53/p63/p73 family
-
11193045
-
De Laurenzi V, Melino G (2000) Evolution of functions within the p53/p63/p73 family. Ann NY Acad Sci 926:90-100
-
(2000)
Ann NY Acad Sci
, vol.926
, pp. 90-100
-
-
De Laurenzi, V.1
Melino, G.2
-
72
-
-
78650873252
-
P63 and p73, the ancestors of p53
-
10.1101/cshperspect.a004887 1:CAS:528:DC%2BC3cXhtlSktLjE 20484388
-
Dotsch V, Bernassola F, Coutandin D, Candi E, Melino G (2010) p63 and p73, the ancestors of p53. Cold Spring Harb Perspect Biol 2(9):a004887. doi: 10.1101/cshperspect.a004887
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.9
, pp. 004887
-
-
Dotsch, V.1
Bernassola, F.2
Coutandin, D.3
Candi, E.4
Melino, G.5
-
73
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
10.1038/16476 1:CAS:528:DyaK1MXntVygtQ%3D%3D 9923679
-
Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M (1999) The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397(6715):164-168. doi: 10.1038/16476
-
(1999)
Nature
, vol.397
, Issue.6715
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
Depinho, R.A.4
Van Lohuizen, M.5
-
74
-
-
0033368883
-
Structure, function and regulation of p63 and p73
-
1:CAS:528:DC%2BD3cXhtV2rtLg%3D 10637429
-
Levrero M, De Laurenzi V, Costanzo A, Gong J, Melino G, Wang JY (1999) Structure, function and regulation of p63 and p73. Cell Death Differ 6(12):1146-1153
-
(1999)
Cell Death Differ
, vol.6
, Issue.12
, pp. 1146-1153
-
-
Levrero, M.1
De Laurenzi, V.2
Costanzo, A.3
Gong, J.4
Melino, G.5
Wang, J.Y.6
-
75
-
-
0034079520
-
The p53/p63/p73 family of transcription factors: Overlapping and distinct functions
-
1:CAS:528:DC%2BD3cXjvFGls7s%3D 10769197
-
Levrero M, De Laurenzi V, Costanzo A, Gong J, Wang JY, Melino G (2000) The p53/p63/p73 family of transcription factors: overlapping and distinct functions. J Cell Sci 113(Pt 10):1661-1670
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 10
, pp. 1661-1670
-
-
Levrero, M.1
De Laurenzi, V.2
Costanzo, A.3
Gong, J.4
Wang, J.Y.5
Melino, G.6
-
76
-
-
32544441224
-
Loss of p53 induces changes in the behaviour of subventricular zone cells: Implication for the genesis of glial tumors
-
10.1523/JNEUROSCI.3970-05.2006 1:CAS:528:DC%2BD28XhsVSjsLc%3D 16436596
-
Gil-Perotin S, Marin-Husstege M, Li J, Soriano-Navarro M, Zindy F, Roussel MF, Garcia-Verdugo JM, Casaccia-Bonnefil P (2006) Loss of p53 induces changes in the behaviour of subventricular zone cells: implication for the genesis of glial tumors. J Neurosci 26(4):1107-1116. doi: 10.1523/JNEUROSCI. 3970-05.2006
-
(2006)
J Neurosci
, vol.26
, Issue.4
, pp. 1107-1116
-
-
Gil-Perotin, S.1
Marin-Husstege, M.2
Li, J.3
Soriano-Navarro, M.4
Zindy, F.5
Roussel, M.F.6
Garcia-Verdugo, J.M.7
Casaccia-Bonnefil, P.8
-
77
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
1:CAS:528:DyaK2cXpslGguw%3D%3D 8242752
-
el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75(4):817-825
-
(1993)
Cell
, vol.75
, Issue.4
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
78
-
-
0033694302
-
Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
-
10.1038/81335 1:CAS:528:DC%2BD3cXotVaqtb8%3D 11062534
-
Cheng T, Rodrigues N, Dombkowski D, Stier S, Scadden DT (2000) Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat Med 6(11):1235-1240. doi: 10.1038/81335
-
(2000)
Nat Med
, vol.6
, Issue.11
, pp. 1235-1240
-
-
Cheng, T.1
Rodrigues, N.2
Dombkowski, D.3
Stier, S.4
Scadden, D.T.5
-
79
-
-
0037088913
-
Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis
-
1:CAS:528:DC%2BD38XisVGitr4%3D 11896165
-
Doetsch F, Verdugo JM, Caille I, Alvarez-Buylla A, Chao MV, Casaccia-Bonnefil P (2002) Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis. J Neurosci 22(6):2255-2264
-
(2002)
J Neurosci
, vol.22
, Issue.6
, pp. 2255-2264
-
-
Doetsch, F.1
Verdugo, J.M.2
Caille, I.3
Alvarez-Buylla, A.4
Chao, M.V.5
Casaccia-Bonnefil, P.6
-
80
-
-
15444377643
-
P21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
-
10.1101/gad.1272305 1:CAS:528:DC%2BD2MXis1Crt7o%3D 15769947
-
Kippin TE, Martens DJ, van der Kooy D (2005) p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev 19(6):756-767. doi: 10.1101/gad.1272305
-
(2005)
Genes Dev
, vol.19
, Issue.6
, pp. 756-767
-
-
Kippin, T.E.1
Martens, D.J.2
Van Der Kooy, D.3
-
81
-
-
33644778697
-
Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo
-
10.1073/pnas.0508476103 1:CAS:528:DC%2BD28XksF2kt7k%3D 16492744
-
Francoz S, Froment P, Bogaerts S, De Clercq S, Maetens M, Doumont G, Bellefroid E, Marine JC (2006) Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo. Proc Natl Acad Sci USA 103(9):3232-3237. doi: 10.1073/pnas.0508476103
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.9
, pp. 3232-3237
-
-
Francoz, S.1
Froment, P.2
Bogaerts, S.3
De Clercq, S.4
Maetens, M.5
Doumont, G.6
Bellefroid, E.7
Marine, J.C.8
-
82
-
-
58549090153
-
Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53
-
10.1016/j.neurobiolaging.2007.07.016 1:CAS:528:DC%2BD1MXhtlGrsb0%3D 17850928
-
Medrano S, Burns-Cusato M, Atienza MB, Rahimi D, Scrable H (2009) Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53. Neurobiol Aging 30(3):483-497. doi: 10.1016/j. neurobiolaging.2007.07.016
-
(2009)
Neurobiol Aging
, vol.30
, Issue.3
, pp. 483-497
-
-
Medrano, S.1
Burns-Cusato, M.2
Atienza, M.B.3
Rahimi, D.4
Scrable, H.5
-
83
-
-
39549096892
-
P21Cip1 restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus
-
10.1073/pnas.0711030105 1:CAS:528:DC%2BD1cXhs1KltrY%3D 18172194
-
Pechnick RN, Zonis S, Wawrowsky K, Pourmorady J, Chesnokova V (2008) p21Cip1 restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus. Proc Natl Acad Sci USA 105(4):1358-1363. doi: 10.1073/pnas.0711030105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.4
, pp. 1358-1363
-
-
Pechnick, R.N.1
Zonis, S.2
Wawrowsky, K.3
Pourmorady, J.4
Chesnokova, V.5
-
84
-
-
63849121231
-
P27(KIP1) regulates neurogenesis in the rostral migratory stream and olfactory bulb of the postnatal mouse
-
10.1523/JNEUROSCI.4051-08.2009 1:CAS:528:DC%2BD1MXjt1Wlsrw%3D 19261886
-
Li X, Tang X, Jablonska B, Aguirre A, Gallo V, Luskin MB (2009) p27(KIP1) regulates neurogenesis in the rostral migratory stream and olfactory bulb of the postnatal mouse. J Neurosci 29(9):2902-2914. doi: 10.1523/JNEUROSCI.4051-08. 2009
-
(2009)
J Neurosci
, vol.29
, Issue.9
, pp. 2902-2914
-
-
Li, X.1
Tang, X.2
Jablonska, B.3
Aguirre, A.4
Gallo, V.5
Luskin, M.B.6
-
85
-
-
0034255133
-
A role for p27/Kip1 in the control of cerebellar granule cell precursor proliferation
-
1:CAS:528:DC%2BD3cXlt1Glur0%3D 10908616
-
Miyazawa K, Himi T, Garcia V, Yamagishi H, Sato S, Ishizaki Y (2000) A role for p27/Kip1 in the control of cerebellar granule cell precursor proliferation. J Neurosci 20(15):5756-5763
-
(2000)
J Neurosci
, vol.20
, Issue.15
, pp. 5756-5763
-
-
Miyazawa, K.1
Himi, T.2
Garcia, V.3
Yamagishi, H.4
Sato, S.5
Ishizaki, Y.6
-
86
-
-
0029981438
-
The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons
-
1:CAS:528:DyaK28XisVWis7s%3D 8622924
-
Lee MH, Nikolic M, Baptista CA, Lai E, Tsai LH, Massague J (1996) The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. Proc Natl Acad Sci USA 93(8):3259-3263
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.8
, pp. 3259-3263
-
-
Lee, M.H.1
Nikolic, M.2
Baptista, C.A.3
Lai, E.4
Tsai, L.H.5
Massague, J.6
-
87
-
-
33744816196
-
P27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex
-
10.1101/gad.377106 1:CAS:528:DC%2BD28XlsF2ktb8%3D 16705040
-
Nguyen L, Besson A, Heng JI, Schuurmans C, Teboul L, Parras C, Philpott A, Roberts JM, Guillemot F (2006) p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev 20(11):1511-1524. doi: 10.1101/gad.377106
-
(2006)
Genes Dev
, vol.20
, Issue.11
, pp. 1511-1524
-
-
Nguyen, L.1
Besson, A.2
Heng, J.I.3
Schuurmans, C.4
Teboul, L.5
Parras, C.6
Philpott, A.7
Roberts, J.M.8
Guillemot, F.9
-
88
-
-
33751255370
-
Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis
-
1:CAS:528:DC%2BD2sXmvVyntg%3D%3D 17102618
-
Nguyen L, Besson A, Roberts JM, Guillemot F (2006) Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis. Cell Cycle 5(20):2314-2318
-
(2006)
Cell Cycle
, vol.5
, Issue.20
, pp. 2314-2318
-
-
Nguyen, L.1
Besson, A.2
Roberts, J.M.3
Guillemot, F.4
-
89
-
-
80053564672
-
Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone
-
10.1111/j.1460-9568.2011.07836.x 21899604
-
Gil-Perotin S, Haines JD, Kaur J, Marin-Husstege M, Spinetta MJ, Kim KH, Duran-Moreno M, Schallert T, Zindy F, Roussel MF, Garcia-Verdugo JM, Casaccia P (2011) Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone. Eur J Neurosci 34(7):1040-1052. doi: 10.1111/j.1460-9568.2011.07836.x
-
(2011)
Eur J Neurosci
, vol.34
, Issue.7
, pp. 1040-1052
-
-
Gil-Perotin, S.1
Haines, J.D.2
Kaur, J.3
Marin-Husstege, M.4
Spinetta, M.J.5
Kim, K.H.6
Duran-Moreno, M.7
Schallert, T.8
Zindy, F.9
Roussel, M.F.10
Garcia-Verdugo, J.M.11
Casaccia, P.12
-
90
-
-
0034854091
-
Regulation of PTEN transcription by p53
-
1:CAS:528:DC%2BD3MXmvFWgsbY%3D 11545734
-
Stambolic V, MacPherson D, Sas D, Lin Y, Snow B, Jang Y, Benchimol S, Mak TW (2001) Regulation of PTEN transcription by p53. Mol Cell 8(2):317-325
-
(2001)
Mol Cell
, vol.8
, Issue.2
, pp. 317-325
-
-
Stambolic, V.1
MacPherson, D.2
Sas, D.3
Lin, Y.4
Snow, B.5
Jang, Y.6
Benchimol, S.7
Mak, T.W.8
-
91
-
-
67650601691
-
Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains
-
10.1101/gad.1799609 1:CAS:528:DC%2BD1MXptVahsrw%3D 19605683
-
Chalhoub N, Zhu G, Zhu X, Baker SJ (2009) Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains. Genes Dev 23(14):1619-1624. doi: 10.1101/gad.1799609
-
(2009)
Genes Dev
, vol.23
, Issue.14
, pp. 1619-1624
-
-
Chalhoub, N.1
Zhu, G.2
Zhu, X.3
Baker, S.J.4
-
92
-
-
54549095950
-
P53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
-
10.1038/nature07443 1:CAS:528:DC%2BD1cXht1yju7rE 18948956
-
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA (2008) p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature 455(7216):1129-1133. doi: 10.1038/nature07443
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1129-1133
-
-
Zheng, H.1
Ying, H.2
Yan, H.3
Kimmelman, A.C.4
Hiller, D.J.5
Chen, A.J.6
Perry, S.R.7
Tonon, G.8
Chu, G.C.9
Ding, Z.10
Stommel, J.M.11
Dunn, K.L.12
Wiedemeyer, R.13
You, M.J.14
Brennan, C.15
Wang, Y.A.16
Ligon, K.L.17
Wong, W.H.18
Chin, L.19
Depinho, R.A.20
more..
-
93
-
-
68549115631
-
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma
-
10.1101/sqb.2008.73.047 1:CAS:528:DC%2BD1MXos1erur0%3D 19150964
-
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA (2008) Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harb Symp Quant Biol 73:427-437. doi: 10.1101/sqb.2008.73.047
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 427-437
-
-
Zheng, H.1
Ying, H.2
Yan, H.3
Kimmelman, A.C.4
Hiller, D.J.5
Chen, A.J.6
Perry, S.R.7
Tonon, G.8
Chu, G.C.9
Ding, Z.10
Stommel, J.M.11
Dunn, K.L.12
Wiedemeyer, R.13
You, M.J.14
Brennan, C.15
Wang, Y.A.16
Ligon, K.L.17
Wong, W.H.18
Chin, L.19
Depinho, R.A.20
more..
-
94
-
-
57849109837
-
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
-
10.1016/j.ccr.2008.12.006 19111880
-
Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF (2009) Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell 15(1):45-56. doi: 10.1016/j.ccr.2008.12.006
-
(2009)
Cancer Cell
, vol.15
, Issue.1
, pp. 45-56
-
-
Alcantara Llaguno, S.1
Chen, J.2
Kwon, C.H.3
Jackson, E.L.4
Li, Y.5
Burns, D.K.6
Alvarez-Buylla, A.7
Parada, L.F.8
-
95
-
-
65649142176
-
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
-
10.1016/j.ccr.2009.04.001 1:CAS:528:DC%2BD1MXntlegtbs%3D 19477430
-
Wang Y, Yang J, Zheng H, Tomasek GJ, Zhang P, McKeever PE, Lee EY, Zhu Y (2009) Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell 15(6):514-526. doi: 10.1016/j.ccr.2009.04.001
-
(2009)
Cancer Cell
, vol.15
, Issue.6
, pp. 514-526
-
-
Wang, Y.1
Yang, J.2
Zheng, H.3
Tomasek, G.J.4
Zhang, P.5
McKeever, P.E.6
Lee, E.Y.7
Zhu, Y.8
-
96
-
-
79960809488
-
Mosaic analysis with double markers reveals tumor cell of origin in glioma
-
10.1016/j.cell.2011.06.014 1:CAS:528:DC%2BC3MXptleksLw%3D 21737130
-
Liu C, Sage JC, Miller MR, Verhaak RG, Hippenmeyer S, Vogel H, Foreman O, Bronson RT, Nishiyama A, Luo L, Zong H (2011) Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell 146(2):209-221. doi: 10.1016/j.cell.2011.06.014
-
(2011)
Cell
, vol.146
, Issue.2
, pp. 209-221
-
-
Liu, C.1
Sage, J.C.2
Miller, M.R.3
Verhaak, R.G.4
Hippenmeyer, S.5
Vogel, H.6
Foreman, O.7
Bronson, R.T.8
Nishiyama, A.9
Luo, L.10
Zong, H.11
-
97
-
-
0030884751
-
A novel protein with strong homology to the tumor suppressor p53
-
10.1038/sj.onc.1201500 1:CAS:528:DyaK2sXmsVSit7o%3D 9315105
-
Schmale H, Bamberger C (1997) A novel protein with strong homology to the tumor suppressor p53. Oncogene 15(11):1363-1367. doi: 10.1038/sj.onc.1201500
-
(1997)
Oncogene
, vol.15
, Issue.11
, pp. 1363-1367
-
-
Schmale, H.1
Bamberger, C.2
-
98
-
-
0032161624
-
P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
1:CAS:528:DyaK1cXmsVyqt7c%3D 9774969
-
Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2(3):305-316
-
(1998)
Mol Cell
, vol.2
, Issue.3
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dotsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
99
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
1:CAS:528:DyaK2sXlvFKmurY%3D 9288759
-
Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, Minty A, Chalon P, Lelias JM, Dumont X, Ferrara P, McKeon F, Caput D (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90(4):809-819
-
(1997)
Cell
, vol.90
, Issue.4
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
Ferrara, P.11
McKeon, F.12
Caput, D.13
-
100
-
-
0031564954
-
P73 is a simian (correction of human) p53-related protein that can induce apoptosis
-
10.1038/38298 1:CAS:528:DyaK2sXmtVSqtLw%3D 9296498
-
Jost CA, Marin MC, Kaelin WG Jr (1997) p73 is a simian (correction of human) p53-related protein that can induce apoptosis. Nature 389(6647):191-194. doi: 10.1038/38298
-
(1997)
Nature
, vol.389
, Issue.6647
, pp. 191-194
-
-
Jost, C.A.1
Marin, M.C.2
Kaelin, Jr.W.G.3
-
101
-
-
33646798450
-
P53/p63/p73 isoforms: An orchestra of isoforms to harmonise cell differentiation and response to stress
-
10.1038/sj.cdd.4401914 1:CAS:528:DC%2BD28Xks1Ortbg%3D 16601753
-
Murray-Zmijewski F, Lane DP, Bourdon JC (2006) p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ 13(6):962-972. doi: 10.1038/sj.cdd.4401914
-
(2006)
Cell Death Differ
, vol.13
, Issue.6
, pp. 962-972
-
-
Murray-Zmijewski, F.1
Lane, D.P.2
Bourdon, J.C.3
-
102
-
-
34547737480
-
P73 suppresses polyploidy and aneuploidy in the absence of functional p53
-
10.1016/j.molcel.2007.06.036 1:CAS:528:DC%2BD2sXhtVSmtL3F 17707235
-
Talos F, Nemajerova A, Flores ER, Petrenko O, Moll UM (2007) p73 suppresses polyploidy and aneuploidy in the absence of functional p53. Mol Cell 27(4):647-659. doi: 10.1016/j.molcel.2007.06.036
-
(2007)
Mol Cell
, vol.27
, Issue.4
, pp. 647-659
-
-
Talos, F.1
Nemajerova, A.2
Flores, E.R.3
Petrenko, O.4
Moll, U.M.5
-
103
-
-
58849134327
-
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity
-
10.1073/pnas.0812096106 1:CAS:528:DC%2BD1MXht12isLY%3D 19139399
-
Tomasini R, Tsuchihara K, Tsuda C, Lau SK, Wilhelm M, Ruffini A, Tsao MS, Iovanna JL, Jurisicova A, Melino G, Mak TW (2009) TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci USA 106(3):797-802. doi: 10.1073/pnas.0812096106
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.3
, pp. 797-802
-
-
Tomasini, R.1
Tsuchihara, K.2
Tsuda, C.3
Lau, S.K.4
Wilhelm, M.5
Ruffini, A.6
Tsao, M.S.7
Iovanna, J.L.8
Jurisicova, A.9
Melino, G.10
Mak, T.W.11
-
104
-
-
53549134949
-
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions
-
10.1101/gad.1695308 1:CAS:528:DC%2BD1cXht1ClsbvK 18805989
-
Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, Jurisicova A, Mak TW (2008) TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev 22(19):2677-2691. doi: 10.1101/gad.1695308
-
(2008)
Genes Dev
, vol.22
, Issue.19
, pp. 2677-2691
-
-
Tomasini, R.1
Tsuchihara, K.2
Wilhelm, M.3
Fujitani, M.4
Rufini, A.5
Cheung, C.C.6
Khan, F.7
Itie-Youten, A.8
Wakeham, A.9
Tsao, M.S.10
Iovanna, J.L.11
Squire, J.12
Jurisica, I.13
Kaplan, D.14
Melino, G.15
Jurisicova, A.16
Mak, T.W.17
-
105
-
-
17744386129
-
Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53
-
10.1038/sj.onc.1204118 1:CAS:528:DC%2BD3MXhsVKjtb4%3D 11313982
-
Fillippovich I, Sorokina N, Gatei M, Haupt Y, Hobson K, Moallem E, Spring K, Mould M, McGuckin MA, Lavin MF, Khanna KK (2001) Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53. Oncogene 20(4):514-522. doi: 10.1038/sj.onc.1204118
-
(2001)
Oncogene
, vol.20
, Issue.4
, pp. 514-522
-
-
Fillippovich, I.1
Sorokina, N.2
Gatei, M.3
Haupt, Y.4
Hobson, K.5
Moallem, E.6
Spring, K.7
Mould, M.8
McGuckin, M.A.9
Lavin, M.F.10
Khanna, K.K.11
-
106
-
-
0034647718
-
An anti-apoptotic role for the p53 family member, p73, during developmental neuron death
-
1:CAS:528:DC%2BD3cXltFeqtrg%3D 10894779
-
Pozniak CD, Radinovic S, Yang A, McKeon F, Kaplan DR, Miller FD (2000) An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science 289(5477):304-306
-
(2000)
Science
, vol.289
, Issue.5477
, pp. 304-306
-
-
Pozniak, C.D.1
Radinovic, S.2
Yang, A.3
McKeon, F.4
Kaplan, D.R.5
Miller, F.D.6
-
107
-
-
77953598591
-
DeltaNp73 transcription factors modulate cell survival and tumor development
-
1:CAS:528:DC%2BC3cXht12qsL7F 20372082
-
Ravni A, Tissir F, Goffinet AM (2010) DeltaNp73 transcription factors modulate cell survival and tumor development. Cell Cycle 9(8):1523-1527
-
(2010)
Cell Cycle
, vol.9
, Issue.8
, pp. 1523-1527
-
-
Ravni, A.1
Tissir, F.2
Goffinet, A.M.3
-
108
-
-
70349733185
-
DeltaNp73 regulates neuronal survival in vivo
-
10.1073/pnas.0903191106 1:CAS:528:DC%2BD1MXht1Oju77K 19805388
-
Tissir F, Ravni A, Achouri Y, Riethmacher D, Meyer G, Goffinet AM (2009) DeltaNp73 regulates neuronal survival in vivo. Proc Natl Acad Sci USA 106(39):16871-16876. doi: 10.1073/pnas.0903191106
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.39
, pp. 16871-16876
-
-
Tissir, F.1
Ravni, A.2
Achouri, Y.3
Riethmacher, D.4
Meyer, G.5
Goffinet, A.M.6
-
109
-
-
0034576495
-
P63 and P73: P53 mimics, menaces and more
-
10.1038/35043127 1:CAS:528:DC%2BD3MXivVGjsLw%3D 11252895
-
Yang A, McKeon F (2000) P63 and P73: P53 mimics, menaces and more. Nat Rev Mol Cell Biol 1(3):199-207. doi: 10.1038/35043127
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, Issue.3
, pp. 199-207
-
-
Yang, A.1
McKeon, F.2
-
110
-
-
0035082243
-
Role of the newer p53 family proteins in malignancy
-
1:CAS:528:DC%2BD3MXivVGrsL4%3D 11321038
-
Irwin MS, Kaelin WG Jr (2001) Role of the newer p53 family proteins in malignancy. Apoptosis 6(1-2):17-29
-
(2001)
Apoptosis
, vol.6
, Issue.1-2
, pp. 17-29
-
-
Irwin, M.S.1
Kaelin, Jr.W.G.2
-
111
-
-
0037041392
-
P63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
10.1038/416560a 1:CAS:528:DC%2BD38XivVOnu7o%3D 11932750
-
Flores ER, Tsai KY, Crowley D, Sengupta S, Yang A, McKeon F, Jacks T (2002) p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 416(6880):560-564. doi: 10.1038/416560a
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
Jacks, T.7
-
112
-
-
17444390129
-
Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family
-
10.1016/j.ccr.2005.02.019 1:CAS:528:DC%2BD2MXjvFSku7w%3D 15837625
-
Flores ER, Sengupta S, Miller JB, Newman JJ, Bronson R, Crowley D, Yang A, McKeon F, Jacks T (2005) Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell 7(4):363-373. doi: 10.1016/j.ccr.2005.02.019
-
(2005)
Cancer Cell
, vol.7
, Issue.4
, pp. 363-373
-
-
Flores, E.R.1
Sengupta, S.2
Miller, J.B.3
Newman, J.J.4
Bronson, R.5
Crowley, D.6
Yang, A.7
McKeon, F.8
Jacks, T.9
-
113
-
-
0033594491
-
P63 is a p53 homologue required for limb and epidermal morphogenesis
-
10.1038/19531 1:CAS:528:DyaK1MXivVegtbo%3D 10227293
-
Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398(6729):708-713. doi: 10.1038/19531
-
(1999)
Nature
, vol.398
, Issue.6729
, pp. 708-713
-
-
Mills, A.A.1
Zheng, B.2
Wang, X.J.3
Vogel, H.4
Roop, D.R.5
Bradley, A.6
-
114
-
-
17544363909
-
P73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
-
10.1038/35003607 1:CAS:528:DC%2BD3cXhvVyqtbo%3D 10716451
-
Yang A, Walker N, Bronson R, Kaghad M, Oosterwegel M, Bonnin J, Vagner C, Bonnet H, Dikkes P, Sharpe A, McKeon F, Caput D (2000) p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature 404(6773):99-103. doi: 10.1038/35003607
-
(2000)
Nature
, vol.404
, Issue.6773
, pp. 99-103
-
-
Yang, A.1
Walker, N.2
Bronson, R.3
Kaghad, M.4
Oosterwegel, M.5
Bonnin, J.6
Vagner, C.7
Bonnet, H.8
Dikkes, P.9
Sharpe, A.10
McKeon, F.11
Caput, D.12
-
115
-
-
84855490109
-
Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets
-
10.1073/pnas.1112061109 1:CAS:528:DC%2BC38XnvVGisQ%3D%3D 22160687
-
Agostini M, Tucci P, Killick R, Candi E, Sayan BS, di Val Rivetti, Cervo P, Nicotera P, McKeon F, Knight RA, Mak TW, Melino G (2011) Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci USA 108(52):21093-21098. doi: 10.1073/pnas.1112061109
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.52
, pp. 21093-21098
-
-
Agostini, M.1
Tucci, P.2
Killick, R.3
Candi, E.4
Sayan, B.S.5
Di Val, R.6
Cervo, P.7
Nicotera, P.8
McKeon, F.9
Knight, R.A.10
Mak, T.W.11
Melino, G.12
-
116
-
-
78649331805
-
TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors
-
10.1016/j.cub.2010.10.029 1:CAS:528:DC%2BC3cXhsVGrtLvI 21074438
-
Fujitani M, Cancino GI, Dugani CB, Weaver IC, Gauthier-Fisher A, Paquin A, Mak TW, Wojtowicz MJ, Miller FD, Kaplan DR (2010) TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors. Curr Biol 20(22):2058-2065. doi: 10.1016/j.cub.2010.10.029
-
(2010)
Curr Biol
, vol.20
, Issue.22
, pp. 2058-2065
-
-
Fujitani, M.1
Cancino, G.I.2
Dugani, C.B.3
Weaver, I.C.4
Gauthier-Fisher, A.5
Paquin, A.6
Mak, T.W.7
Wojtowicz, M.J.8
Miller, F.D.9
Kaplan, D.R.10
-
117
-
-
79951870202
-
While p73 is essential, p63 is completely dispensable for the development of the central nervous system
-
1:CAS:528:DC%2BC3MXkt1CksL0%3D 21293190
-
Holembowski L, Schulz R, Talos F, Scheel A, Wolff S, Dobbelstein M, Moll U (2011) While p73 is essential, p63 is completely dispensable for the development of the central nervous system. Cell Cycle 10(4):680-689
-
(2011)
Cell Cycle
, vol.10
, Issue.4
, pp. 680-689
-
-
Holembowski, L.1
Schulz, R.2
Talos, F.3
Scheel, A.4
Wolff, S.5
Dobbelstein, M.6
Moll, U.7
-
118
-
-
77949362925
-
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway
-
10.1101/gad.1873910 1:CAS:528:DC%2BC3cXktFOksrY%3D 20194434
-
Wilhelm MT, Rufini A, Wetzel MK, Tsuchihara K, Inoue S, Tomasini R, Itie-Youten A, Wakeham A, Arsenian-Henriksson M, Melino G, Kaplan DR, Miller FD, Mak TW (2010) Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev 24(6):549-560. doi: 10.1101/gad.1873910
-
(2010)
Genes Dev
, vol.24
, Issue.6
, pp. 549-560
-
-
Wilhelm, M.T.1
Rufini, A.2
Wetzel, M.K.3
Tsuchihara, K.4
Inoue, S.5
Tomasini, R.6
Itie-Youten, A.7
Wakeham, A.8
Arsenian-Henriksson, M.9
Melino, G.10
Kaplan, D.R.11
Miller, F.D.12
Mak, T.W.13
-
119
-
-
79959286263
-
DeltaNp63 regulates stem cell dynamics in the mammalian olfactory epithelium
-
10.1523/JNEUROSCI.0681-11.2011 1:CAS:528:DC%2BC3MXotVOqtL0%3D 21677159
-
Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE (2011) DeltaNp63 regulates stem cell dynamics in the mammalian olfactory epithelium. J Neurosci 31(24):8748-8759. doi: 10.1523/JNEUROSCI.0681-11.2011
-
(2011)
J Neurosci
, vol.31
, Issue.24
, pp. 8748-8759
-
-
Packard, A.1
Schnittke, N.2
Romano, R.A.3
Sinha, S.4
Schwob, J.E.5
-
120
-
-
83355175406
-
P63 regulates olfactory stem cell self-renewal and differentiation
-
10.1016/j.neuron.2011.09.009 1:CAS:528:DC%2BC3MXhs1Shtb%2FF 22153372
-
Fletcher RB, Prasol MS, Estrada J, Baudhuin A, Vranizan K, Choi YG, Ngai J (2011) p63 regulates olfactory stem cell self-renewal and differentiation. Neuron 72(5):748-759. doi: 10.1016/j.neuron.2011.09.009
-
(2011)
Neuron
, vol.72
, Issue.5
, pp. 748-759
-
-
Fletcher, R.B.1
Prasol, M.S.2
Estrada, J.3
Baudhuin, A.4
Vranizan, K.5
Choi, Y.G.6
Ngai, J.7
-
121
-
-
66249121719
-
P63 antagonizes p53 to promote the survival of embryonic neural precursor cells
-
10.1523/JNEUROSCI.5878-08.2009 1:CAS:528:DC%2BD1MXmsFentLs%3D 19458240
-
Dugani CB, Paquin A, Fujitani M, Kaplan DR, Miller FD (2009) p63 antagonizes p53 to promote the survival of embryonic neural precursor cells. J Neurosci 29(20):6710-6721. doi: 10.1523/JNEUROSCI.5878-08.2009
-
(2009)
J Neurosci
, vol.29
, Issue.20
, pp. 6710-6721
-
-
Dugani, C.B.1
Paquin, A.2
Fujitani, M.3
Kaplan, D.R.4
Miller, F.D.5
-
122
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
10.1038/323643a0 1:CAS:528:DyaL2sXhtl2qsw%3D%3D 2877398
-
Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323(6089):643-646. doi: 10.1038/323643a0
-
(1986)
Nature
, vol.323
, Issue.6089
, pp. 643-646
-
-
Friend, S.H.1
Bernards, R.2
Rogelj, S.3
Weinberg, R.A.4
Rapaport, J.M.5
Albert, D.M.6
Dryja, T.P.7
-
123
-
-
0023222707
-
Structural evidence for the authenticity of the human retinoblastoma gene
-
1:CAS:528:DyaL2sXksFGhu70%3D 2885916
-
Fung YK, Murphree AL, T'Ang A, Qian J, Hinrichs SH, Benedict WF (1987) Structural evidence for the authenticity of the human retinoblastoma gene. Science 236(4809):1657-1661
-
(1987)
Science
, vol.236
, Issue.4809
, pp. 1657-1661
-
-
Fung, Y.K.1
Murphree, A.L.2
T'Ang, A.3
Qian, J.4
Hinrichs, S.H.5
Benedict, W.F.6
-
124
-
-
0023106062
-
Human retinoblastoma susceptibility gene: Cloning, identification, and sequence
-
1:CAS:528:DyaL2sXktlCitrY%3D 3823889
-
Lee WH, Bookstein R, Hong F, Young LJ, Shew JY, Lee EY (1987) Human retinoblastoma susceptibility gene: cloning, identification, and sequence. Science 235(4794):1394-1399
-
(1987)
Science
, vol.235
, Issue.4794
, pp. 1394-1399
-
-
Lee, W.H.1
Bookstein, R.2
Hong, F.3
Young, L.J.4
Shew, J.Y.5
Lee, E.Y.6
-
125
-
-
0026337295
-
Tumor suppressor genes
-
1:CAS:528:DyaK38Xls1CjsA%3D%3D 1659741
-
Weinberg RA (1991) Tumor suppressor genes. Science 254(5035):1138-1146
-
(1991)
Science
, vol.254
, Issue.5035
, pp. 1138-1146
-
-
Weinberg, R.A.1
-
126
-
-
0027279891
-
Identification of germline mutations in the RB1 gene by denaturant gradient gel electrophoresis and polymerase chain reaction direct sequencing
-
1:CAS:528:DyaK3sXlslymsLg%3D 8364580
-
Blanquet V, Turleau C, Gross MS, Goossens M, Besmond C (1993) Identification of germline mutations in the RB1 gene by denaturant gradient gel electrophoresis and polymerase chain reaction direct sequencing. Hum Mol Genet 2(7):975-979
-
(1993)
Hum Mol Genet
, vol.2
, Issue.7
, pp. 975-979
-
-
Blanquet, V.1
Turleau, C.2
Gross, M.S.3
Goossens, M.4
Besmond, C.5
-
127
-
-
0036884829
-
The retinoblastoma tumour suppressor in development and cancer
-
10.1038/nrc950 1:CAS:528:DC%2BD38XptFCjsb8%3D 12459729
-
Classon M, Harlow E (2002) The retinoblastoma tumour suppressor in development and cancer. Nat Rev Cancer 2(12):910-917. doi: 10.1038/nrc950
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.12
, pp. 910-917
-
-
Classon, M.1
Harlow, E.2
-
128
-
-
13444249786
-
The search for the retinoblastoma cell of origin
-
10.1038/nrc1545 1:CAS:528:DC%2BD2MXoslKktQ%3D%3D 15685194
-
Dyer MA, Bremner R (2005) The search for the retinoblastoma cell of origin. Nat Rev Cancer 5(2):91-101. doi: 10.1038/nrc1545
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.2
, pp. 91-101
-
-
Dyer, M.A.1
Bremner, R.2
-
129
-
-
0024515741
-
Binding of the Rb1 protein to E1A products is required for adenovirus transformation
-
1:CAS:528:DyaL1MXkt1SksL8%3D 2523032
-
Egan C, Bayley ST, Branton PE (1989) Binding of the Rb1 protein to E1A products is required for adenovirus transformation. Oncogene 4(3):383-388
-
(1989)
Oncogene
, vol.4
, Issue.3
, pp. 383-388
-
-
Egan, C.1
Bayley, S.T.2
Branton, P.E.3
-
130
-
-
0023686773
-
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
-
1:CAS:528:DyaL1cXlt1emsbo%3D 2838909
-
Harbour JW, Lai SL, Whang-Peng J, Gazdar AF, Minna JD, Kaye FJ (1988) Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241(4863):353-357
-
(1988)
Science
, vol.241
, Issue.4863
, pp. 353-357
-
-
Harbour, J.W.1
Lai, S.L.2
Whang-Peng, J.3
Gazdar, A.F.4
Minna, J.D.5
Kaye, F.J.6
-
131
-
-
0025304297
-
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
-
1:CAS:528:DyaK3cXitleitLw%3D 2181449
-
Horowitz JM, Park SH, Bogenmann E, Cheng JC, Yandell DW, Kaye FJ, Minna JD, Dryja TP, Weinberg RA (1990) Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc Natl Acad Sci USA 87(7):2775-2779
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, Issue.7
, pp. 2775-2779
-
-
Horowitz, J.M.1
Park, S.H.2
Bogenmann, E.3
Cheng, J.C.4
Yandell, D.W.5
Kaye, F.J.6
Minna, J.D.7
Dryja, T.P.8
Weinberg, R.A.9
-
132
-
-
0023914010
-
Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product
-
10.1038/334124a0 1:CAS:528:DyaL1cXkvVOgu7k%3D 2968522
-
Whyte P, Buchkovich KJ, Horowitz JM, Friend SH, Raybuck M, Weinberg RA, Harlow E (1988) Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 334(6178):124-129. doi: 10.1038/334124a0
-
(1988)
Nature
, vol.334
, Issue.6178
, pp. 124-129
-
-
Whyte, P.1
Buchkovich, K.J.2
Horowitz, J.M.3
Friend, S.H.4
Raybuck, M.5
Weinberg, R.A.6
Harlow, E.7
-
133
-
-
0023731010
-
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
-
1:CAS:528:DyaL1cXls1Kqs7Y%3D 2839300
-
DeCaprio JA, Ludlow JW, Figge J, Shew JY, Huang CM, Lee WH, Marsilio E, Paucha E, Livingston DM (1988) SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54(2):275-283
-
(1988)
Cell
, vol.54
, Issue.2
, pp. 275-283
-
-
Decaprio, J.A.1
Ludlow, J.W.2
Figge, J.3
Shew, J.Y.4
Huang, C.M.5
Lee, W.H.6
Marsilio, E.7
Paucha, E.8
Livingston, D.M.9
-
134
-
-
0024535228
-
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
-
1:CAS:528:DyaL1MXhslWjs7k%3D 2537532
-
Dyson N, Howley PM, Munger K, Harlow E (1989) The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243(4893):934-937
-
(1989)
Science
, vol.243
, Issue.4893
, pp. 934-937
-
-
Dyson, N.1
Howley, P.M.2
Munger, K.3
Harlow, E.4
-
135
-
-
0024809865
-
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product
-
1:STN:280:DyaK3c%2Fns1Wgsw%3D%3D 2556261
-
Munger K, Werness BA, Dyson N, Phelps WC, Harlow E, Howley PM (1989) Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. Embo J 8(13):4099-4105
-
(1989)
Embo J
, vol.8
, Issue.13
, pp. 4099-4105
-
-
Munger, K.1
Werness, B.A.2
Dyson, N.3
Phelps, W.C.4
Harlow, E.5
Howley, P.M.6
-
136
-
-
0025273737
-
The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations
-
1:CAS:528:DyaK3cXitleitbo%3D 2138977
-
Hu QJ, Dyson N, Harlow E (1990) The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations. Embo J 9(4):1147-1155
-
(1990)
Embo J
, vol.9
, Issue.4
, pp. 1147-1155
-
-
Hu, Q.J.1
Dyson, N.2
Harlow, E.3
-
137
-
-
0033786378
-
Rb function in cell-cycle regulation and apoptosis
-
10.1038/35008695 1:CAS:528:DC%2BD3cXivVSlsrg%3D 10783254
-
Harbour JW, Dean DC (2000) Rb function in cell-cycle regulation and apoptosis. Nat Cell Biol 2(4):E65-E67. doi: 10.1038/35008695
-
(2000)
Nat Cell Biol
, vol.2
, Issue.4
-
-
Harbour, J.W.1
Dean, D.C.2
-
138
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
1:CAS:528:DyaK2MXlsFSrs7k%3D 7736585
-
Weinberg RA (1995) The retinoblastoma protein and cell cycle control. Cell 81(3):323-330
-
(1995)
Cell
, vol.81
, Issue.3
, pp. 323-330
-
-
Weinberg, R.A.1
-
139
-
-
0024439444
-
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
-
1:CAS:528:DyaL1MXmtFamsbc%3D 2673543
-
Buchkovich K, Duffy LA, Harlow E (1989) The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58(6):1097-1105
-
(1989)
Cell
, vol.58
, Issue.6
, pp. 1097-1105
-
-
Buchkovich, K.1
Duffy, L.A.2
Harlow, E.3
-
140
-
-
0035028719
-
Revisiting retinoblastoma protein phosphorylation during the mammalian cell cycle
-
1:CAS:528:DC%2BD3MXktVWns7g%3D 11361093
-
Cooper S, Shayman JA (2001) Revisiting retinoblastoma protein phosphorylation during the mammalian cell cycle. Cell Mol Life Sci 58(4):580-595
-
(2001)
Cell Mol Life Sci
, vol.58
, Issue.4
, pp. 580-595
-
-
Cooper, S.1
Shayman, J.A.2
-
141
-
-
0032549001
-
Rb interacts with histone deacetylase to repress transcription
-
1:CAS:528:DyaK1cXhsVKnsb8%3D 9491888
-
Luo RX, Postigo AA, Dean DC (1998) Rb interacts with histone deacetylase to repress transcription. Cell 92(4):463-473
-
(1998)
Cell
, vol.92
, Issue.4
, pp. 463-473
-
-
Luo, R.X.1
Postigo, A.A.2
Dean, D.C.3
-
142
-
-
77954498022
-
Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive
-
10.1101/gad.1917610 1:CAS:528:DC%2BC3cXpt1CntL0%3D 20551166
-
Coschi CH, Martens AL, Ritchie K, Francis SM, Chakrabarti S, Berube NG, Dick FA (2010) Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive. Genes Dev 24(13):1351-1363. doi: 10.1101/gad.1917610
-
(2010)
Genes Dev
, vol.24
, Issue.13
, pp. 1351-1363
-
-
Coschi, C.H.1
Martens, A.L.2
Ritchie, K.3
Francis, S.M.4
Chakrabarti, S.5
Berube, N.G.6
Dick, F.A.7
-
143
-
-
84857654700
-
RB: Mitotic implications of a tumour suppressor
-
10.1038/nrc3216 1:CAS:528:DC%2BC38XitVWntLo%3D 22318235
-
Manning AL, Dyson NJ (2012) RB: mitotic implications of a tumour suppressor. Nat Rev Cancer 12(3):220-226. doi: 10.1038/nrc3216
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.3
, pp. 220-226
-
-
Manning, A.L.1
Dyson, N.J.2
-
144
-
-
77954516489
-
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling
-
10.1101/gad.580710 20551164
-
van Harn T, Foijer F, van Vugt M, Banerjee R, Yang F, Oostra A, Joenje H, te Riele H (2010) Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes Dev 24(13):1377-1388. doi: 10.1101/gad.580710
-
(2010)
Genes Dev
, vol.24
, Issue.13
, pp. 1377-1388
-
-
Van Harn, T.1
Foijer, F.2
Van Vugt, M.3
Banerjee, R.4
Yang, F.5
Oostra, A.6
Joenje, H.7
Te Riele, H.8
-
145
-
-
77954526477
-
RB's original CIN?
-
10.1101/gad.1948010 1:CAS:528:DC%2BC3cXpt1Cnt7c%3D 20551167
-
Sage J, Straight AF (2010) RB's original CIN? Genes Dev 24(13):1329-1333. doi: 10.1101/gad.1948010
-
(2010)
Genes Dev
, vol.24
, Issue.13
, pp. 1329-1333
-
-
Sage, J.1
Straight, A.F.2
-
146
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
10.1038/359328a0 1:CAS:528:DyaK38XmtV2mtbs%3D 1406937
-
Clarke AR, Maandag ER, van Roon M, van der Lugt NM, van der Valk M, Hooper ML, Berns A, te Riele H (1992) Requirement for a functional Rb-1 gene in murine development. Nature 359(6393):328-330. doi: 10.1038/359328a0
-
(1992)
Nature
, vol.359
, Issue.6393
, pp. 328-330
-
-
Clarke, A.R.1
Maandag, E.R.2
Van Roon, M.3
Van Der Lugt, N.M.4
Van Der Valk, M.5
Hooper, M.L.6
Berns, A.7
Te Riele, H.8
-
147
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
10.1038/359295a0 1:CAS:528:DyaK38XlvV2hu7s%3D 1406933
-
Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA (1992) Effects of an Rb mutation in the mouse. Nature 359(6393):295-300. doi: 10.1038/359295a0
-
(1992)
Nature
, vol.359
, Issue.6393
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
148
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
10.1038/359288a0 1:CAS:528:DyaK38XmtV2mtbo%3D 1406932
-
Lee EY, Chang CY, Hu N, Wang YC, Lai CC, Herrup K, Lee WH, Bradley A (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359(6393):288-294. doi: 10.1038/359288a0
-
(1992)
Nature
, vol.359
, Issue.6393
, pp. 288-294
-
-
Lee, E.Y.1
Chang, C.Y.2
Hu, N.3
Wang, Y.C.4
Lai, C.C.5
Herrup, K.6
Lee, W.H.7
Bradley, A.8
-
149
-
-
0029819994
-
PRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis
-
1:CAS:528:DyaK28XnsV2ltL8%3D 8957005
-
Zacksenhaus E, Jiang Z, Chung D, Marth JD, Phillips RA, Gallie BL (1996) pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev 10(23):3051-3064
-
(1996)
Genes Dev
, vol.10
, Issue.23
, pp. 3051-3064
-
-
Zacksenhaus, E.1
Jiang, Z.2
Chung, D.3
Marth, J.D.4
Phillips, R.A.5
Gallie, B.L.6
-
150
-
-
0028131540
-
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
-
1:CAS:528:DyaK2cXmt1Ogtrw%3D 7958874
-
Lee EY, Hu N, Yuan SS, Cox LA, Bradley A, Lee WH, Herrup K (1994) Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev 8(17):2008-2021
-
(1994)
Genes Dev
, vol.8
, Issue.17
, pp. 2008-2021
-
-
Lee, E.Y.1
Hu, N.2
Yuan, S.S.3
Cox, L.A.4
Bradley, A.5
Lee, W.H.6
Herrup, K.7
-
151
-
-
0035796491
-
Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system
-
10.1093/emboj/20.13.3402 1:CAS:528:DC%2BD3MXlsVCgtrk%3D 11432828
-
Lipinski MM, Macleod KF, Williams BO, Mullaney TL, Crowley D, Jacks T (2001) Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system. Embo J 20(13):3402-3413. doi: 10.1093/emboj/20.13.3402
-
(2001)
Embo J
, vol.20
, Issue.13
, pp. 3402-3413
-
-
Lipinski, M.M.1
MacLeod, K.F.2
Williams, B.O.3
Mullaney, T.L.4
Crowley, D.5
Jacks, T.6
-
152
-
-
18444389748
-
Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development
-
10.1093/emboj/cdf338 1:CAS:528:DC%2BD38XlsFCgtL0%3D 12093735
-
Ferguson KL, Vanderluit JL, Hebert JM, McIntosh WC, Tibbo E, MacLaurin JG, Park DS, Wallace VA, Vooijs M, McConnell SK, Slack RS (2002) Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development. Embo J 21(13):3337-3346. doi: 10.1093/emboj/cdf338
-
(2002)
Embo J
, vol.21
, Issue.13
, pp. 3337-3346
-
-
Ferguson, K.L.1
Vanderluit, J.L.2
Hebert, J.M.3
McIntosh, W.C.4
Tibbo, E.5
MacLaurin, J.G.6
Park, D.S.7
Wallace, V.A.8
Vooijs, M.9
McConnell, S.K.10
Slack, R.S.11
-
153
-
-
2942512013
-
Cell type-specific effects of Rb deletion in the murine retina
-
10.1101/gad.1203304 1:CAS:528:DC%2BD2cXlvFKltrc%3D 15231717
-
MacPherson D, Sage J, Kim T, Ho D, McLaughlin ME, Jacks T (2004) Cell type-specific effects of Rb deletion in the murine retina. Genes Dev 18(14):1681-1694. doi: 10.1101/gad.1203304
-
(2004)
Genes Dev
, vol.18
, Issue.14
, pp. 1681-1694
-
-
MacPherson, D.1
Sage, J.2
Kim, T.3
Ho, D.4
McLaughlin, M.E.5
Jacks, T.6
-
154
-
-
0042977676
-
Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence
-
1:CAS:528:DC%2BD3sXms1WhtLo%3D 12810584
-
Marino S, Hoogervoorst D, Brandner S, Berns A (2003) Rb and p107 are
-
(2003)
Development
, vol.130
, Issue.15
, pp. 3359-3368
-
-
Marino, S.1
Hoogervoorst, D.2
Brandner, S.3
Berns, A.4
-
155
-
-
29244475774
-
A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration
-
10.1038/sj.emboj.7600887 1:CAS:528:DC%2BD2MXhtlanu7zN 16308563
-
Ferguson KL, McClellan KA, Vanderluit JL, McIntosh WC, Schuurmans C, Polleux F, Slack RS (2005) A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration. Embo J 24(24):4381-4391. doi: 10.1038/sj.emboj.7600887
-
(2005)
Embo J
, vol.24
, Issue.24
, pp. 4381-4391
-
-
Ferguson, K.L.1
McClellan, K.A.2
Vanderluit, J.L.3
McIntosh, W.C.4
Schuurmans, C.5
Polleux, F.6
Slack, R.S.7
-
156
-
-
0026547060
-
Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins
-
1:CAS:528:DyaK38XnvVyhsA%3D%3D 1532457
-
Ewen ME, Faha B, Harlow E, Livingston DM (1992) Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins. Science 255(5040):85-87
-
(1992)
Science
, vol.255
, Issue.5040
, pp. 85-87
-
-
Ewen, M.E.1
Faha, B.2
Harlow, E.3
Livingston, D.M.4
-
157
-
-
0025785484
-
Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein
-
1:CAS:528:DyaK3sXhtFOktbs%3D 1833063
-
Ewen ME, Xing YG, Lawrence JB, Livingston DM (1991) Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell 66(6):1155-1164
-
(1991)
Cell
, vol.66
, Issue.6
, pp. 1155-1164
-
-
Ewen, M.E.1
Xing, Y.G.2
Lawrence, J.B.3
Livingston, D.M.4
-
158
-
-
0027142956
-
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins
-
1:CAS:528:DyaK2cXpslKjuw%3D%3D 8253384
-
Hannon GJ, Demetrick D, Beach D (1993) Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev 7(12A):2378-2391
-
(1993)
Genes Dev
, vol.7
, Issue.12 A
, pp. 2378-2391
-
-
Hannon, G.J.1
Demetrick, D.2
Beach, D.3
-
159
-
-
0027135209
-
The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and e
-
1:CAS:528:DyaK2cXht1Oqtb4%3D 8253383
-
Li Y, Graham C, Lacy S, Duncan AM, Whyte P (1993) The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev 7(12A):2366-2377
-
(1993)
Genes Dev
, vol.7
, Issue.12 A
, pp. 2366-2377
-
-
Li, Y.1
Graham, C.2
Lacy, S.3
Duncan, A.M.4
Whyte, P.5
-
160
-
-
12044258811
-
Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain
-
1:CAS:528:DyaK2cXjtVSm 8361765
-
Mayol X, Grana X, Baldi A, Sang N, Hu Q, Giordano A (1993) Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene 8(9):2561-2566
-
(1993)
Oncogene
, vol.8
, Issue.9
, pp. 2561-2566
-
-
Mayol, X.1
Grana, X.2
Baldi, A.3
Sang, N.4
Hu, Q.5
Giordano, A.6
-
161
-
-
18344383345
-
Pocket proteins and cell cycle control
-
10.1038/sj.onc.1208619 1:CAS:528:DC%2BD2MXjtlehsL0%3D 15838516
-
Cobrinik D (2005) Pocket proteins and cell cycle control. Oncogene 24(17):2796-2809. doi: 10.1038/sj.onc.1208619
-
(2005)
Oncogene
, vol.24
, Issue.17
, pp. 2796-2809
-
-
Cobrinik, D.1
-
162
-
-
0036371956
-
Sibling rivalry in the E2F family
-
10.1038/nrm714 1:CAS:528:DC%2BD38XhtFGmsbw%3D 11823794
-
Trimarchi JM, Lees JA (2002) Sibling rivalry in the E2F family. Nat Rev Mol Cell Biol 3(1):11-20. doi: 10.1038/nrm714
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, Issue.1
, pp. 11-20
-
-
Trimarchi, J.M.1
Lees, J.A.2
-
163
-
-
0031831681
-
The retinoblastoma gene family: Cousins with overlapping interests
-
1:CAS:528:DyaK1cXjslantLY%3D 9635405
-
Mulligan G, Jacks T (1998) The retinoblastoma gene family: cousins with overlapping interests. Trends Genet 14(6):223-229
-
(1998)
Trends Genet
, vol.14
, Issue.6
, pp. 223-229
-
-
Mulligan, G.1
Jacks, T.2
-
164
-
-
9444242683
-
Shared role of the pRB-related p130 and p107 proteins in limb development
-
1:CAS:528:DyaK28Xkt1CksLo%3D 8682294
-
Cobrinik D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, Harlow E, Beach D, Weinberg RA, Jacks T (1996) Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev 10(13):1633-1644
-
(1996)
Genes Dev
, vol.10
, Issue.13
, pp. 1633-1644
-
-
Cobrinik, D.1
Lee, M.H.2
Hannon, G.3
Mulligan, G.4
Bronson, R.T.5
Dyson, N.6
Harlow, E.7
Beach, D.8
Weinberg, R.A.9
Jacks, T.10
-
165
-
-
0029736909
-
Targeted disruption of p107: Functional overlap between p107 and Rb
-
1:CAS:528:DyaK28Xkt1CksL0%3D 8682293
-
Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, Dyson N, Harlow E, Jacks T (1996) Targeted disruption of p107: functional overlap between p107 and Rb. Genes Dev 10(13):1621-1632
-
(1996)
Genes Dev
, vol.10
, Issue.13
, pp. 1621-1632
-
-
Lee, M.H.1
Williams, B.O.2
Mulligan, G.3
Mukai, S.4
Bronson, R.T.5
Dyson, N.6
Harlow, E.7
Jacks, T.8
-
166
-
-
0033559609
-
Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity
-
10.1006/dbio.1998.9162 1:CAS:528:DyaK1MXhsFajtLs%3D 10068462
-
Callaghan DA, Dong L, Callaghan SM, Hou YX, Dagnino L, Slack RS (1999) Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity. Dev Biol 207(2):257-270. doi: 10.1006/dbio.1998.9162
-
(1999)
Dev Biol
, vol.207
, Issue.2
, pp. 257-270
-
-
Callaghan, D.A.1
Dong, L.2
Callaghan, S.M.3
Hou, Y.X.4
Dagnino, L.5
Slack, R.S.6
-
167
-
-
33745304849
-
Compensation by tumor suppressor genes during retinal development in mice and humans
-
10.1186/1741-7007-4-14 16672052
-
Donovan SL, Schweers B, Martins R, Johnson D, Dyer MA (2006) Compensation by tumor suppressor genes during retinal development in mice and humans. BMC Biol 4:14. doi: 10.1186/1741-7007-4-14
-
(2006)
BMC Biol
, vol.4
, pp. 14
-
-
Donovan, S.L.1
Schweers, B.2
Martins, R.3
Johnson, D.4
Dyer, M.A.5
-
168
-
-
35348849572
-
Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice
-
10.1016/j.cell.2007.09.036 1:CAS:528:DC%2BD2sXht1KqsbfM 17956737
-
Ajioka I, Martins RA, Bayazitov IT, Donovan S, Johnson DA, Frase S, Cicero SA, Boyd K, Zakharenko SS, Dyer MA (2007) Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice. Cell 131(2):378-390. doi: 10.1016/j.cell.2007.09.036
-
(2007)
Cell
, vol.131
, Issue.2
, pp. 378-390
-
-
Ajioka, I.1
Martins, R.A.2
Bayazitov, I.T.3
Donovan, S.4
Johnson, D.A.5
Frase, S.6
Cicero, S.A.7
Boyd, K.8
Zakharenko, S.S.9
Dyer, M.A.10
-
169
-
-
66449114034
-
Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling
-
10.1016/j.cell.2009.03.051 1:CAS:528:DC%2BD1MXps1eiurk%3D 19524506
-
Xu XL, Fang Y, Lee TC, Forrest D, Gregory-Evans C, Almeida D, Liu A, Jhanwar SC, Abramson DH, Cobrinik D (2009) Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling. Cell 137(6):1018-1031. doi: 10.1016/j.cell.2009.03.051
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1018-1031
-
-
Xu, X.L.1
Fang, Y.2
Lee, T.C.3
Forrest, D.4
Gregory-Evans, C.5
Almeida, D.6
Liu, A.7
Jhanwar, S.C.8
Abramson, D.H.9
Cobrinik, D.10
-
170
-
-
75649109727
-
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes
-
10.1038/emboj.2009.327 1:CAS:528:DC%2BD1MXhsVSmu7vE 19927122
-
Jacques TS, Swales A, Brzozowski MJ, Henriquez NV, Linehan JM, Mirzadeh Z, O'Malley C, Naumann H, Alvarez-Buylla A, Brandner S (2010) Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes. Embo J 29(1):222-235. doi: 10.1038/emboj.2009.327
-
(2010)
Embo J
, vol.29
, Issue.1
, pp. 222-235
-
-
Jacques, T.S.1
Swales, A.2
Brzozowski, M.J.3
Henriquez, N.V.4
Linehan, J.M.5
Mirzadeh, Z.6
O'Malley, C.7
Naumann, H.8
Alvarez-Buylla, A.9
Brandner, S.10
-
171
-
-
0034656212
-
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
-
1:CAS:528:DC%2BD3cXivFyltrk%3D 10783170
-
Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A (2000) Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev 14(8):994-1004
-
(2000)
Genes Dev
, vol.14
, Issue.8
, pp. 994-1004
-
-
Marino, S.1
Vooijs, M.2
Van Der Gulden, H.3
Jonkers, J.4
Berns, A.5
-
172
-
-
0036490954
-
Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation
-
1:CAS:528:DC%2BD38XivVegsbs%3D 12086874
-
Xiao A, Wu H, Pandolfi PP, Louis DN, Van Dyke T (2002) Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell 1(2):157-168
-
(2002)
Cancer Cell
, vol.1
, Issue.2
, pp. 157-168
-
-
Xiao, A.1
Wu, H.2
Pandolfi, P.P.3
Louis, D.N.4
Van Dyke, T.5
-
173
-
-
4544363898
-
P107 regulates neural precursor cells in the mammalian brain
-
10.1083/jcb.200403156 1:CAS:528:DC%2BD2cXns1yhtLY%3D 15353549
-
Vanderluit JL, Ferguson KL, Nikoletopoulou V, Parker M, Ruzhynsky V, Alexson T, McNamara SM, Park DS, Rudnicki M, Slack RS (2004) p107 regulates neural precursor cells in the mammalian brain. J Cell Biol 166(6):853-863. doi: 10.1083/jcb.200403156
-
(2004)
J Cell Biol
, vol.166
, Issue.6
, pp. 853-863
-
-
Vanderluit, J.L.1
Ferguson, K.L.2
Nikoletopoulou, V.3
Parker, M.4
Ruzhynsky, V.5
Alexson, T.6
McNamara, S.M.7
Park, D.S.8
Rudnicki, M.9
Slack, R.S.10
-
174
-
-
34347392919
-
The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate
-
10.1083/jcb.200703176 1:CAS:528:DC%2BD2sXnsVaju78%3D 17591923
-
Vanderluit JL, Wylie CA, McClellan KA, Ghanem N, Fortin A, Callaghan S, MacLaurin JG, Park DS, Slack RS (2007) The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate. J Cell Biol 178(1):129-139. doi: 10.1083/jcb.200703176
-
(2007)
J Cell Biol
, vol.178
, Issue.1
, pp. 129-139
-
-
Vanderluit, J.L.1
Wylie, C.A.2
McClellan, K.A.3
Ghanem, N.4
Fortin, A.5
Callaghan, S.6
MacLaurin, J.G.7
Park, D.S.8
Slack, R.S.9
-
175
-
-
68849119333
-
The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells
-
10.1128/MCB.01767-08 1:CAS:528:DC%2BD1MXhtFWgs7zL 19564414
-
McClellan KA, Vanderluit JL, Julian LM, Andrusiak MG, Dugal-Tessier D, Park DS, Slack RS (2009) The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells. Mol Cell Biol 29(17):4701-4713. doi: 10.1128/MCB.01767-08
-
(2009)
Mol Cell Biol
, vol.29
, Issue.17
, pp. 4701-4713
-
-
McClellan, K.A.1
Vanderluit, J.L.2
Julian, L.M.3
Andrusiak, M.G.4
Dugal-Tessier, D.5
Park, D.S.6
Slack, R.S.7
-
176
-
-
0025089467
-
Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17
-
1:CAS:528:DyaK3cXmtV2itLY%3D 2218500
-
Borrow J, Goddard AD, Sheer D, Solomon E (1990) Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17. Science 249(4976):1577-1580
-
(1990)
Science
, vol.249
, Issue.4976
, pp. 1577-1580
-
-
Borrow, J.1
Goddard, A.D.2
Sheer, D.3
Solomon, E.4
-
177
-
-
0025043959
-
The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus
-
10.1038/347558a0 2170850
-
de The H, Chomienne C, Lanotte M, Degos L, Dejean A (1990) The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus. Nature 347(6293):558-561. doi: 10.1038/347558a0
-
(1990)
Nature
, vol.347
, Issue.6293
, pp. 558-561
-
-
De The, H.1
Chomienne, C.2
Lanotte, M.3
Degos, L.4
Dejean, A.5
-
178
-
-
0025875679
-
The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
-
1652369
-
de The H, Lavau C, Marchio A, Chomienne C, Degos L, Dejean A (1991) The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 66(4):675-684
-
(1991)
Cell
, vol.66
, Issue.4
, pp. 675-684
-
-
De The, H.1
Lavau, C.2
Marchio, A.3
Chomienne, C.4
Degos, L.5
Dejean, A.6
-
179
-
-
0025646509
-
Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias
-
1:CAS:528:DyaK3cXmtV2isbc%3D 2175343
-
Longo L, Pandolfi PP, Biondi A, Rambaldi A, Mencarelli A, Lo Coco F, Diverio D, Pegoraro L, Avanzi G, Tabilio A et al (1990) Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias. J Exp Med 172(6):1571-1575
-
(1990)
J Exp Med
, vol.172
, Issue.6
, pp. 1571-1575
-
-
Longo, L.1
Pandolfi, P.P.2
Biondi, A.3
Rambaldi, A.4
Mencarelli, A.5
Lo Coco, F.6
Diverio, D.7
Pegoraro, L.8
Avanzi, G.9
Tabilio, A.10
-
180
-
-
0033561797
-
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
-
1:CAS:528:DyaK1MXjtVKqurg%3D 10233871
-
Melnick A, Licht JD (1999) Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93(10):3167-3215
-
(1999)
Blood
, vol.93
, Issue.10
, pp. 3167-3215
-
-
Melnick, A.1
Licht, J.D.2
-
181
-
-
0025917413
-
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties
-
1:CAS:528:DyaK38XktVajsrs%3D 1650447
-
Pandolfi PP, Grignani F, Alcalay M, Mencarelli A, Biondi A, LoCoco F, Pelicci PG (1991) Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties. Oncogene 6(7):1285-1292
-
(1991)
Oncogene
, vol.6
, Issue.7
, pp. 1285-1292
-
-
Pandolfi, P.P.1
Grignani, F.2
Alcalay, M.3
Mencarelli, A.4
Biondi, A.5
Lococo, F.6
Pelicci, P.G.7
-
182
-
-
0025780876
-
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML
-
1:CAS:528:DyaK38Xlt1Gls74%3D 1652368
-
Kakizuka A, Miller WH Jr, Umesono K, Warrell RP Jr, Frankel SR, Murty VV, Dmitrovsky E, Evans RM (1991) Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 66(4):663-674
-
(1991)
Cell
, vol.66
, Issue.4
, pp. 663-674
-
-
Kakizuka, A.1
Miller, Jr.W.H.2
Umesono, K.3
Warrell, Jr.R.P.4
Frankel, S.R.5
Murty, V.V.6
Dmitrovsky, E.7
Evans, R.M.8
-
183
-
-
0026513504
-
Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia
-
1:CAS:528:DyaK38Xitlaqsbs%3D 1314166
-
Pandolfi PP, Alcalay M, Fagioli M, Zangrilli D, Mencarelli A, Diverio D, Biondi A, Lo Coco F, Rambaldi A, Grignani F et al (1992) Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia. Embo J 11(4):1397-1407
-
(1992)
Embo J
, vol.11
, Issue.4
, pp. 1397-1407
-
-
Pandolfi, P.P.1
Alcalay, M.2
Fagioli, M.3
Zangrilli, D.4
Mencarelli, A.5
Diverio, D.6
Biondi, A.7
Lo Coco, F.8
Rambaldi, A.9
Grignani, F.10
-
184
-
-
0037169341
-
The role of PML in tumor suppression
-
1:CAS:528:DC%2BD38XhtV2hsLY%3D 11832207
-
Salomoni P, Pandolfi PP (2002) The role of PML in tumor suppression. Cell 108(2):165-170
-
(2002)
Cell
, vol.108
, Issue.2
, pp. 165-170
-
-
Salomoni, P.1
Pandolfi, P.P.2
-
185
-
-
0031791875
-
PML is essential for multiple apoptotic pathways
-
10.1038/3073 1:CAS:528:DyaK1cXntFOisL0%3D 9806545
-
Wang ZG, Ruggero D, Ronchetti S, Zhong S, Gaboli M, Rivi R, Pandolfi PP (1998) PML is essential for multiple apoptotic pathways. Nat Genet 20(3):266-272. doi: 10.1038/3073
-
(1998)
Nat Genet
, vol.20
, Issue.3
, pp. 266-272
-
-
Wang, Z.G.1
Ruggero, D.2
Ronchetti, S.3
Zhong, S.4
Gaboli, M.5
Rivi, R.6
Pandolfi, P.P.7
-
186
-
-
0032721540
-
PML is critical for ND10 formation and recruits the PML-interacting protein DAXX to this nuclear structure when modified by SUMO-1
-
1:CAS:528:DyaK1MXmslCqsrg%3D 10525530
-
Ishov AM, Sotnikov AG, Negorev D, Vladimirova OV, Neff N, Kamitani T, Yeh ET, Strauss JF 3rd, Maul GG (1999) PML is critical for ND10 formation and recruits the PML-interacting protein DAXX to this nuclear structure when modified by SUMO-1. J Cell Biol 147(2):221-234
-
(1999)
J Cell Biol
, vol.147
, Issue.2
, pp. 221-234
-
-
Ishov, A.M.1
Sotnikov, A.G.2
Negorev, D.3
Vladimirova, O.V.4
Neff, N.5
Kamitani, T.6
Yeh, E.T.7
Strauss III, J.F.8
Maul, G.G.9
-
188
-
-
33750447586
-
The mechanisms of PML-nuclear body formation
-
10.1016/j.molcel.2006.09.013 1:CAS:528:DC%2BD28XhtF2qs7jO 17081985
-
Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP (2006) The mechanisms of PML-nuclear body formation. Mol Cell 24(3):331-339. doi: 10.1016/j.molcel.2006.09.013
-
(2006)
Mol Cell
, vol.24
, Issue.3
, pp. 331-339
-
-
Shen, T.H.1
Lin, H.K.2
Scaglioni, P.P.3
Yung, T.M.4
Pandolfi, P.P.5
-
189
-
-
63849293624
-
Perspectives in PML: A unifying framework for PML function
-
1:CAS:528:DC%2BD1MXltFejsbo%3D 19273081
-
Borden KL, Culjkovic B (2009) Perspectives in PML: a unifying framework for PML function. Front Biosci 14:497-509
-
(2009)
Front Biosci
, vol.14
, pp. 497-509
-
-
Borden, K.L.1
Culjkovic, B.2
-
190
-
-
63849264344
-
PML links aberrant cytokine signaling and oncogenic stress to cellular senescence
-
1:CAS:528:DC%2BD1MXltFejsbw%3D 19273079
-
Bourdeau V, Baudry D, Ferbeyre G (2009) PML links aberrant cytokine signaling and oncogenic stress to cellular senescence. Front Biosci 14:475-485
-
(2009)
Front Biosci
, vol.14
, pp. 475-485
-
-
Bourdeau, V.1
Baudry, D.2
Ferbeyre, G.3
-
191
-
-
0346147033
-
Body language: The function of PML nuclear bodies in apoptosis regulation
-
10.1038/sj.cdd.4401313 1:CAS:528:DC%2BD3sXptVCktbs%3D 12934066
-
Hofmann TG, Will H (2003) Body language: the function of PML nuclear bodies in apoptosis regulation. Cell Death Differ 10(12):1290-1299. doi: 10.1038/sj.cdd.4401313
-
(2003)
Cell Death Differ
, vol.10
, Issue.12
, pp. 1290-1299
-
-
Hofmann, T.G.1
Will, H.2
-
192
-
-
0035969104
-
PML interaction with p53 and its role in apoptosis and replicative senescence
-
10.1038/sj.onc.1204856 1:CAS:528:DC%2BD3MXos1Onu7g%3D 11704853
-
Pearson M, Pelicci PG (2001) PML interaction with p53 and its role in apoptosis and replicative senescence. Oncogene 20(49):7250-7256. doi: 10.1038/sj.onc.1204856
-
(2001)
Oncogene
, vol.20
, Issue.49
, pp. 7250-7256
-
-
Pearson, M.1
Pelicci, P.G.2
-
193
-
-
44849143636
-
New insights into the role of PML in tumour suppression
-
10.1038/cr.2008.58 1:CAS:528:DC%2BD1cXmsFegtLc%3D 18504460
-
Salomoni P, Ferguson BJ, Wyllie AH, Rich T (2008) New insights into the role of PML in tumour suppression. Cell Res 18(6):622-640. doi: 10.1038/cr.2008.58
-
(2008)
Cell Res
, vol.18
, Issue.6
, pp. 622-640
-
-
Salomoni, P.1
Ferguson, B.J.2
Wyllie, A.H.3
Rich, T.4
-
194
-
-
2442711599
-
PML nuclear bodies and apoptosis
-
10.1038/sj.onc.1207533 1:CAS:528:DC%2BD2cXivFKmsLc%3D 15077145
-
Takahashi Y, Lallemand-Breitenbach V, Zhu J, de The H (2004) PML nuclear bodies and apoptosis. Oncogene 23(16):2819-2824. doi: 10.1038/sj.onc.1207533
-
(2004)
Oncogene
, vol.23
, Issue.16
, pp. 2819-2824
-
-
Takahashi, Y.1
Lallemand-Breitenbach, V.2
Zhu, J.3
De The, H.4
-
195
-
-
58849151893
-
The tumor suppressor PML regulates cell fate in the developing neocortex
-
10.1038/nn.2251 1:CAS:528:DC%2BD1MXktVagug%3D%3D 19136970
-
Regad T, Bellodi C, Nicotera P, Salomoni P (2009) The tumor suppressor PML regulates cell fate in the developing neocortex. Nat Neurosci 12(2):132-140. doi: 10.1038/nn.2251
-
(2009)
Nat Neurosci
, vol.12
, Issue.2
, pp. 132-140
-
-
Regad, T.1
Bellodi, C.2
Nicotera, P.3
Salomoni, P.4
-
196
-
-
84859641689
-
Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation
-
10.1016/j.neuron.2012.02.021 1:CAS:528:DC%2BC38Xls1ehsbw%3D 22500635
-
Michod D, Bartesaghi S, Khelifi A, Bellodi C, Berliocchi L, Nicotera P, Salomoni P (2012) Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation. Neuron 74(1):122-135. doi: 10.1016/j.neuron.2012.02.021
-
(2012)
Neuron
, vol.74
, Issue.1
, pp. 122-135
-
-
Michod, D.1
Bartesaghi, S.2
Khelifi, A.3
Bellodi, C.4
Berliocchi, L.5
Nicotera, P.6
Salomoni, P.7
-
197
-
-
77953955724
-
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
-
10.1101/gad.566910 1:CAS:528:DC%2BC3cXotlaisr0%3D 20504901
-
Drane P, Ouararhni K, Depaux A, Shuaib M, Hamiche A (2010) The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. Genes Dev 24(12):1253-1265. doi: 10.1101/gad.566910
-
(2010)
Genes Dev
, vol.24
, Issue.12
, pp. 1253-1265
-
-
Drane, P.1
Ouararhni, K.2
Depaux, A.3
Shuaib, M.4
Hamiche, A.5
-
198
-
-
77956282773
-
DAXX is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
-
10.1073/pnas.1008850107 1:CAS:528:DC%2BC3cXhtVCktrfO 20651253
-
Lewis PW, Elsaesser SJ, Noh KM, Stadler SC, Allis CD (2010) DAXX is an H3.3-specific histone chaperone and cooperates with ATRX in replication- independent chromatin assembly at telomeres. Proc Natl Acad Sci USA 107(32):14075-14080. doi: 10.1073/pnas.1008850107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.32
, pp. 14075-14080
-
-
Lewis, P.W.1
Elsaesser, S.J.2
Noh, K.M.3
Stadler, S.C.4
Allis, C.D.5
-
199
-
-
14944359718
-
The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis
-
10.1172/JCI22329 1:CAS:528:DC%2BD2MXhtFyjsLw%3D 15668733
-
Berube NG, Mangelsdorf M, Jagla M, Vanderluit J, Garrick D, Gibbons RJ, Higgs DR, Slack RS, Picketts DJ (2005) The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clin Invest 115(2):258-267. doi: 10.1172/JCI22329
-
(2005)
J Clin Invest
, vol.115
, Issue.2
, pp. 258-267
-
-
Berube, N.G.1
Mangelsdorf, M.2
Jagla, M.3
Vanderluit, J.4
Garrick, D.5
Gibbons, R.J.6
Higgs, D.R.7
Slack, R.S.8
Picketts, D.J.9
-
200
-
-
44349166602
-
PML targeting eradicates quiescent leukaemia-initiating cells
-
10.1038/nature07016 1:CAS:528:DC%2BD1cXntlGjtb0%3D 18469801
-
Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y, Rosenblatt J, Avigan DE, Teruya-Feldstein J, Pandolfi PP (2008) PML targeting eradicates quiescent leukaemia-initiating cells. Nature 453(7198):1072-1078. doi: 10.1038/nature07016
-
(2008)
Nature
, vol.453
, Issue.7198
, pp. 1072-1078
-
-
Ito, K.1
Bernardi, R.2
Morotti, A.3
Matsuoka, S.4
Saglio, G.5
Ikeda, Y.6
Rosenblatt, J.7
Avigan, D.E.8
Teruya-Feldstein, J.9
Pandolfi, P.P.10
-
201
-
-
77956233247
-
A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal
-
10.1016/j.stem.2010.05.016 1:CAS:528:DC%2BC3cXhtVyrt7%2FM 20619763
-
Milyavsky M, Gan OI, Trottier M, Komosa M, Tabach O, Notta F, Lechman E, Hermans KG, Eppert K, Konovalova Z, Ornatsky O, Domany E, Meyn MS, Dick JE (2010) A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal. Cell Stem Cell 7(2):186-197. doi: 10.1016/j.stem.2010.05.016
-
(2010)
Cell Stem Cell
, vol.7
, Issue.2
, pp. 186-197
-
-
Milyavsky, M.1
Gan, O.I.2
Trottier, M.3
Komosa, M.4
Tabach, O.5
Notta, F.6
Lechman, E.7
Hermans, K.G.8
Eppert, K.9
Konovalova, Z.10
Ornatsky, O.11
Domany, E.12
Meyn, M.S.13
Dick, J.E.14
-
202
-
-
63849185620
-
PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool
-
10.1073/pnas.0807640106 1:CAS:528:DC%2BD1MXktFOgtL0%3D 19261859
-
Li W, Ferguson BJ, Khaled WT, Tevendale M, Stingl J, Poli V, Rich T, Salomoni P, Watson CJ (2009) PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool. Proc Natl Acad Sci USA 106(12):4725-4730. doi: 10.1073/pnas.0807640106
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.12
, pp. 4725-4730
-
-
Li, W.1
Ferguson, B.J.2
Khaled, W.T.3
Tevendale, M.4
Stingl, J.5
Poli, V.6
Rich, T.7
Salomoni, P.8
Watson, C.J.9
-
203
-
-
79958706507
-
The role of PML in the nervous system
-
10.1007/s12035-010-8156-y 1:CAS:528:DC%2BC3MXjs1Cnt7Y%3D 21161613
-
Salomoni P, Betts-Henderson J (2011) The role of PML in the nervous system. Mol Neurobiol 43(2):114-123. doi: 10.1007/s12035-010-8156-y
-
(2011)
Mol Neurobiol
, vol.43
, Issue.2
, pp. 114-123
-
-
Salomoni, P.1
Betts-Henderson, J.2
-
204
-
-
1342291118
-
Loss of the tumor suppressor PML in human cancers of multiple histologic origins
-
1:CAS:528:DC%2BD2cXhsV2qtLY%3D 14970276
-
Gurrieri C, Capodieci P, Bernardi R, Scaglioni PP, Nafa K, Rush LJ, Verbel DA, Cordon-Cardo C, Pandolfi PP (2004) Loss of the tumor suppressor PML in human cancers of multiple histologic origins. J Natl Cancer Inst 96(4):269-279
-
(2004)
J Natl Cancer Inst
, vol.96
, Issue.4
, pp. 269-279
-
-
Gurrieri, C.1
Capodieci, P.2
Bernardi, R.3
Scaglioni, P.P.4
Nafa, K.5
Rush, L.J.6
Verbel, D.A.7
Cordon-Cardo, C.8
Pandolfi, P.P.9
-
205
-
-
77951599543
-
Targeting brain cancer: Advances in the molecular pathology of malignant glioma and medulloblastoma
-
10.1038/nrc2818 1:CAS:528:DC%2BC3cXltV2ks7w%3D 20414201
-
Huse JT, Holland EC (2010) Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer 10(5):319-331. doi: 10.1038/nrc2818
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.5
, pp. 319-331
-
-
Huse, J.T.1
Holland, E.C.2
-
206
-
-
77954287020
-
PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3
-
10.1016/j.ccr.2010.06.003 1:CAS:528:DC%2BC3cXpslSjtL8%3D 20609355
-
Jeanne M, Lallemand-Breitenbach V, Ferhi O, Koken M, Le Bras M, Duffort S, Peres L, Berthier C, Soilihi H, Raught B, de The H (2010) PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3. Cancer Cell 18(1):88-98. doi: 10.1016/j.ccr.2010.06.003
-
(2010)
Cancer Cell
, vol.18
, Issue.1
, pp. 88-98
-
-
Jeanne, M.1
Lallemand-Breitenbach, V.2
Ferhi, O.3
Koken, M.4
Le Bras, M.5
Duffort, S.6
Peres, L.7
Berthier, C.8
Soilihi, H.9
Raught, B.10
De The, H.11
-
207
-
-
77950826446
-
Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML
-
10.1126/science.1183424 1:CAS:528:DC%2BC3cXkt1Cgt7k%3D 20378816
-
Zhang XW, Yan XJ, Zhou ZR, Yang FF, Wu ZY, Sun HB, Liang WX, Song AX, Lallemand-Breitenbach V, Jeanne M, Zhang QY, Yang HY, Huang QH, Zhou GB, Tong JH, Zhang Y, Wu JH, Hu HY, de The H, Chen SJ, Chen Z (2010) Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science 328(5975):240-243. doi: 10.1126/science.1183424
-
(2010)
Science
, vol.328
, Issue.5975
, pp. 240-243
-
-
Zhang, X.W.1
Yan, X.J.2
Zhou, Z.R.3
Yang, F.F.4
Wu, Z.Y.5
Sun, H.B.6
Liang, W.X.7
Song, A.X.8
Lallemand-Breitenbach, V.9
Jeanne, M.10
Zhang, Q.Y.11
Yang, H.Y.12
Huang, Q.H.13
Zhou, G.B.14
Tong, J.H.15
Zhang, Y.16
Wu, J.H.17
Hu, H.Y.18
De The, H.19
Chen, S.J.20
Chen, Z.21
more..
-
208
-
-
0027525653
-
Characterization and chromosomal localization of the human proto-oncogene BMI-1
-
1:CAS:528:DyaK2cXpslCqug%3D%3D 8268912
-
Alkema MJ, Wiegant J, Raap AK, Berns A, van Lohuizen M (1993) Characterization and chromosomal localization of the human proto-oncogene BMI-1. Hum Mol Genet 2(10):1597-1603
-
(1993)
Hum Mol Genet
, vol.2
, Issue.10
, pp. 1597-1603
-
-
Alkema, M.J.1
Wiegant, J.2
Raap, A.K.3
Berns, A.4
Van Lohuizen, M.5
-
209
-
-
84857367297
-
RYBP-PRC1 complexes mediate H2A ubiquitylation at Polycomb target sites independently of PRC2 and H3 K27me3
-
10.1016/j.cell.2011.12.029 1:CAS:528:DC%2BC38XitFKhtLo%3D 22325148
-
Tavares L, Dimitrova E, Oxley D, Webster J, Poot R, Demmers J, Bezstarosti K, Taylor S, Ura H, Koide H, Wutz A, Vidal M, Elderkin S, Brockdorff N (2012) RYBP-PRC1 complexes mediate H2A ubiquitylation at Polycomb target sites independently of PRC2 and H3 K27me3. Cell 148(4):664-678. doi: 10.1016/j.cell.2011.12.029
-
(2012)
Cell
, vol.148
, Issue.4
, pp. 664-678
-
-
Tavares, L.1
Dimitrova, E.2
Oxley, D.3
Webster, J.4
Poot, R.5
Demmers, J.6
Bezstarosti, K.7
Taylor, S.8
Ura, H.9
Koide, H.10
Wutz, A.11
Vidal, M.12
Elderkin, S.13
Brockdorff, N.14
-
210
-
-
77951605788
-
The Hox genes and their roles in oncogenesis
-
10.1038/nrc2826 1:CAS:528:DC%2BC3cXktVGju7g%3D 20357775
-
Shah N, Sukumar S (2010) The Hox genes and their roles in oncogenesis. Nat Rev Cancer 10(5):361-371. doi: 10.1038/nrc2826
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.5
, pp. 361-371
-
-
Shah, N.1
Sukumar, S.2
-
211
-
-
84856756676
-
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs
-
10.1016/j.stem.2011.12.017 1:CAS:528:DC%2BC38XhvFaqtbo%3D 22305566
-
Brookes E, de Santiago I, Hebenstreit D, Morris KJ, Carroll T, Xie SQ, Stock JK, Heidemann M, Eick D, Nozaki N, Kimura H, Ragoussis J, Teichmann SA, Pombo A (2012) Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell 10(2):157-170. doi: 10.1016/j.stem.2011.12.017
-
(2012)
Cell Stem Cell
, vol.10
, Issue.2
, pp. 157-170
-
-
Brookes, E.1
De Santiago, I.2
Hebenstreit, D.3
Morris, K.J.4
Carroll, T.5
Xie, S.Q.6
Stock, J.K.7
Heidemann, M.8
Eick, D.9
Nozaki, N.10
Kimura, H.11
Ragoussis, J.12
Teichmann, S.A.13
Pombo, A.14
-
212
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
10.1038/nature02060 1:CAS:528:DC%2BD3sXosVOht7w%3D 14574365
-
Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ (2003) Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425(6961):962-967. doi: 10.1038/nature02060
-
(2003)
Nature
, vol.425
, Issue.6961
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.K.4
Clarke, M.F.5
Morrison, S.J.6
-
213
-
-
0028201742
-
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene
-
7926765
-
van der Lugt NM, Domen J, Linders K, van Roon M, Robanus-Maandag E, te Riele H, van der Valk M, Deschamps J, Sofroniew M, van Lohuizen M et al (1994) Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. Genes Dev 8(7):757-769
-
(1994)
Genes Dev
, vol.8
, Issue.7
, pp. 757-769
-
-
Van Der Lugt, N.M.1
Domen, J.2
Linders, K.3
Van Roon, M.4
Robanus-Maandag, E.5
Te Riele, H.6
Van Der Valk, M.7
Deschamps, J.8
Sofroniew, M.9
Van Lohuizen, M.10
-
214
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
1:CAS:528:DyaK2MXhtVSnu7fM 8521522
-
Quelle DE, Zindy F, Ashmun RA, Sherr CJ (1995) Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 83(6):993-1000
-
(1995)
Cell
, vol.83
, Issue.6
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
215
-
-
0033037541
-
The INK4A/ARF locus and its two gene products
-
1:CAS:528:DyaK1MXhsFSnt7c%3D 10072356
-
Sharpless NE, DePinho RA (1999) The INK4A/ARF locus and its two gene products. Curr Opin Genet Dev 9(1):22-30
-
(1999)
Curr Opin Genet Dev
, vol.9
, Issue.1
, pp. 22-30
-
-
Sharpless, N.E.1
Depinho, R.A.2
-
216
-
-
33747819484
-
Divorcing ARF and p53: An unsettled case
-
10.1038/nrc1954 1:CAS:528:DC%2BD28XosVOmsLk%3D 16915296
-
Sherr CJ (2006) Divorcing ARF and p53: an unsettled case. Nat Rev Cancer 6(9):663-673. doi: 10.1038/nrc1954
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.9
, pp. 663-673
-
-
Sherr, C.J.1
-
217
-
-
1342289563
-
Bmi1, stem cells, and senescence regulation
-
10.1172/JCI20800 1:CAS:528:DC%2BD2cXmsVyrsg%3D%3D 14722607
-
Park IK, Morrison SJ, Clarke MF (2004) Bmi1, stem cells, and senescence regulation. J Clin Invest 113(2):175-179. doi: 10.1172/JCI20800
-
(2004)
J Clin Invest
, vol.113
, Issue.2
, pp. 175-179
-
-
Park, I.K.1
Morrison, S.J.2
Clarke, M.F.3
-
218
-
-
74249099090
-
P53 stabilization: The importance of nuclear import
-
10.1038/cdd.2009.183 20062067
-
Marine JC (2010) p53 stabilization: the importance of nuclear import. Cell Death Differ 17(2):191-192. doi: 10.1038/cdd.2009.183
-
(2010)
Cell Death Differ
, vol.17
, Issue.2
, pp. 191-192
-
-
Marine, J.C.1
-
219
-
-
0035906853
-
The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression
-
10.1054/bjoc.2001.1791 1:CAS:528:DC%2BD3MXkslKgurY%3D 11355949
-
Vonlanthen S, Heighway J, Altermatt HJ, Gugger M, Kappeler A, Borner MM, van Lohuizen M, Betticher DC (2001) The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression. Br J Cancer 84(10):1372-1376. doi: 10.1054/bjoc.2001.1791
-
(2001)
Br J Cancer
, vol.84
, Issue.10
, pp. 1372-1376
-
-
Vonlanthen, S.1
Heighway, J.2
Altermatt, H.J.3
Gugger, M.4
Kappeler, A.5
Borner, M.M.6
Van Lohuizen, M.7
Betticher, D.C.8
-
220
-
-
34249907279
-
ShRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development
-
10.1016/j.stem.2007.04.001 1:CAS:528:DC%2BD2sXptV2rs7w%3D 18371338
-
Fasano CA, Dimos JT, Ivanova NB, Lowry N, Lemischka IR, Temple S (2007) shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell Stem Cell 1(1):87-99. doi: 10.1016/j.stem.2007.04.001
-
(2007)
Cell Stem Cell
, vol.1
, Issue.1
, pp. 87-99
-
-
Fasano, C.A.1
Dimos, J.T.2
Ivanova, N.B.3
Lowry, N.4
Lemischka, I.R.5
Temple, S.6
-
221
-
-
77955772813
-
Bmi1 directly represses p21Waf1/Cip1 in Shh-induced proliferation of cerebellar granule cell progenitors
-
10.1016/j.mcn.2010.06.006 1:CAS:528:DC%2BC3cXhtVeht73F 20600931
-
Subkhankulova T, Zhang X, Leung C, Marino S (2010) Bmi1 directly represses p21Waf1/Cip1 in Shh-induced proliferation of cerebellar granule cell progenitors. Mol Cell Neurosci 45(2):151-162. doi: 10.1016/j.mcn.2010.06.006
-
(2010)
Mol Cell Neurosci
, vol.45
, Issue.2
, pp. 151-162
-
-
Subkhankulova, T.1
Zhang, X.2
Leung, C.3
Marino, S.4
-
222
-
-
61849144426
-
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain
-
10.1101/gad.1743709 1:CAS:528:DC%2BD1MXjsVals7o%3D 19270157
-
Fasano CA, Phoenix TN, Kokovay E, Lowry N, Elkabetz Y, Dimos JT, Lemischka IR, Studer L, Temple S (2009) Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev 23(5):561-574. doi: 10.1101/gad.1743709
-
(2009)
Genes Dev
, vol.23
, Issue.5
, pp. 561-574
-
-
Fasano, C.A.1
Phoenix, T.N.2
Kokovay, E.3
Lowry, N.4
Elkabetz, Y.5
Dimos, J.T.6
Lemischka, I.R.7
Studer, L.8
Temple, S.9
-
223
-
-
1642633053
-
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
-
10.1038/nature02385 1:CAS:528:DC%2BD2cXitFCnur8%3D 15029199
-
Leung C, Lingbeek M, Shakhova O, Liu J, Tanger E, Saremaslani P, Van Lohuizen M, Marino S (2004) Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 428(6980):337-341. doi: 10.1038/nature02385
-
(2004)
Nature
, vol.428
, Issue.6980
, pp. 337-341
-
-
Leung, C.1
Lingbeek, M.2
Shakhova, O.3
Liu, J.4
Tanger, E.5
Saremaslani, P.6
Van Lohuizen, M.7
Marino, S.8
-
224
-
-
11844301282
-
Medulloblastoma: Developmental mechanisms out of control
-
10.1016/j.molmed.2004.11.008 1:CAS:528:DC%2BD2MXksVajuw%3D%3D 15649818
-
Marino S (2005) Medulloblastoma: developmental mechanisms out of control. Trends Mol Med 11(1):17-22. doi: 10.1016/j.molmed.2004.11.008
-
(2005)
Trends Mol Med
, vol.11
, Issue.1
, pp. 17-22
-
-
Marino, S.1
-
225
-
-
66549099504
-
The heterogeneity of adult neural stem cells and the emerging complexity of their niche
-
10.1101/sqb.2008.73.019 1:CAS:528:DC%2BD1MXos1ertbg%3D 19022766
-
Alvarez-Buylla A, Kohwi M, Nguyen TM, Merkle FT (2008) The heterogeneity of adult neural stem cells and the emerging complexity of their niche. Cold Spring Harb Symp Quant Biol 73:357-365. doi: 10.1101/sqb.2008.73.019
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 357-365
-
-
Alvarez-Buylla, A.1
Kohwi, M.2
Nguyen, T.M.3
Merkle, F.T.4
-
226
-
-
0031928716
-
Stem cells in the developing and adult nervous system
-
1:STN:280:DyaK1czns1WnsQ%3D%3D 9712298
-
Alvarez-Buylla A, Temple S (1998) Stem cells in the developing and adult nervous system. J Neurobiol 36(2):105-110
-
(1998)
J Neurobiol
, vol.36
, Issue.2
, pp. 105-110
-
-
Alvarez-Buylla, A.1
Temple, S.2
-
227
-
-
0031820136
-
In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain
-
1:CAS:528:DyaK1cXksFanu7g%3D 9584124
-
Morshead CM, Craig CG, van der Kooy D (1998) In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain. Development 125(12):2251-2261
-
(1998)
Development
, vol.125
, Issue.12
, pp. 2251-2261
-
-
Morshead, C.M.1
Craig, C.G.2
Van Der Kooy, D.3
-
228
-
-
0037104668
-
Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsiveness
-
1:CAS:528:DC%2BD38XmslSlsb8%3D 12194866
-
Kruger GM, Mosher JT, Bixby S, Joseph N, Iwashita T, Morrison SJ (2002) Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsiveness. Neuron 35(4):657-669
-
(2002)
Neuron
, vol.35
, Issue.4
, pp. 657-669
-
-
Kruger, G.M.1
Mosher, J.T.2
Bixby, S.3
Joseph, N.4
Iwashita, T.5
Morrison, S.J.6
-
229
-
-
22344449361
-
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
-
10.1101/gad.1299505 1:CAS:528:DC%2BD2MXlslChurc%3D 15964994
-
Molofsky AV, He S, Bydon M, Morrison SJ, Pardal R (2005) Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev 19(12):1432-1437. doi: 10.1101/gad.1299505
-
(2005)
Genes Dev
, vol.19
, Issue.12
, pp. 1432-1437
-
-
Molofsky, A.V.1
He, S.2
Bydon, M.3
Morrison, S.J.4
Pardal, R.5
-
230
-
-
67349156082
-
Bmi1 regulates mitochondrial function and the DNA damage response pathway
-
10.1038/nature08040 1:CAS:528:DC%2BD1MXlt1SrsbY%3D 19404261
-
Liu J, Cao L, Chen J, Song S, Lee IH, Quijano C, Liu H, Keyvanfar K, Chen H, Cao LY, Ahn BH, Kumar NG, Rovira II, Xu XL, van Lohuizen M, Motoyama N, Deng CX, Finkel T (2009) Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature 459(7245):387-392. doi: 10.1038/nature08040
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 387-392
-
-
Liu, J.1
Cao, L.2
Chen, J.3
Song, S.4
Lee, I.H.5
Quijano, C.6
Liu, H.7
Keyvanfar, K.8
Chen, H.9
Cao, L.Y.10
Ahn, B.H.11
Kumar, N.G.12
Rovira, I.I.13
Xu, X.L.14
Van Lohuizen, M.15
Motoyama, N.16
Deng, C.X.17
Finkel, T.18
-
231
-
-
58849166901
-
The Polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity
-
10.1523/JNEUROSCI.5303-08.2009 1:CAS:528:DC%2BD1MXhtVKru7c%3D 19144853
-
Chatoo W, Abdouh M, David J, Champagne MP, Ferreira J, Rodier F, Bernier G (2009) The Polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity. J Neurosci 29(2):529-542. doi: 10.1523/JNEUROSCI.5303-08.2009
-
(2009)
J Neurosci
, vol.29
, Issue.2
, pp. 529-542
-
-
Chatoo, W.1
Abdouh, M.2
David, J.3
Champagne, M.P.4
Ferreira, J.5
Rodier, F.6
Bernier, G.7
-
232
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
10.1038/nature02989 1:CAS:528:DC%2BD2cXoslSlt78%3D 15496926
-
Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Hamaguchi I, Nomiyama K, Hosokawa K, Sakurada K, Nakagata N, Ikeda Y, Mak TW, Suda T (2004) Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 431(7011):997-1002. doi: 10.1038/nature02989
-
(2004)
Nature
, vol.431
, Issue.7011
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
Nomiyama, K.7
Hosokawa, K.8
Sakurada, K.9
Nakagata, N.10
Ikeda, Y.11
Mak, T.W.12
Suda, T.13
-
233
-
-
78650968492
-
Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner
-
10.1016/j.stem.2010.11.028 21211782
-
Le Belle JE, Orozco NM, Paucar AA, Saxe JP, Mottahedeh J, Pyle AD, Wu H, Kornblum HI (2011) Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. Cell Stem Cell 8(1):59-71. doi: 10.1016/j.stem.2010.11.028
-
(2011)
Cell Stem Cell
, vol.8
, Issue.1
, pp. 59-71
-
-
Le Belle, J.E.1
Orozco, N.M.2
Paucar, A.A.3
Saxe, J.P.4
Mottahedeh, J.5
Pyle, A.D.6
Wu, H.7
Kornblum, H.I.8
-
234
-
-
47749128298
-
Stem cell protein BMI-1 is an independent marker for poor prognosis in oligodendroglial tumours
-
10.1111/j.1365-2990.2008.00949.x 1:CAS:528:DC%2BD1cXhtlWit7jI 18346113
-
Hayry V, Tynninen O, Haapasalo HK, Wolfer J, Paulus W, Hasselblatt M, Sariola H, Paetau A, Sarna S, Niemela M, Wartiovaara K, Nupponen NN (2008) Stem cell protein BMI-1 is an independent marker for poor prognosis in oligodendroglial tumours. Neuropathol Appl Neurobiol 34(5):555-563. doi: 10.1111/j.1365-2990.2008.00949.x
-
(2008)
Neuropathol Appl Neurobiol
, vol.34
, Issue.5
, pp. 555-563
-
-
Hayry, V.1
Tynninen, O.2
Haapasalo, H.K.3
Wolfer, J.4
Paulus, W.5
Hasselblatt, M.6
Sariola, H.7
Paetau, A.8
Sarna, S.9
Niemela, M.10
Wartiovaara, K.11
Nupponen, N.N.12
-
235
-
-
49749101982
-
Expression of the Polycomb-group protein BMI1 and correlation with p16 in astrocytomas an immunohistochemical study on 80 cases
-
10.1016/j.prp.2008.02.007 18450386
-
Tirabosco R, De Maglio G, Skrap M, Falconieri G, Pizzolitto S (2008) Expression of the Polycomb-group protein BMI1 and correlation with p16 in astrocytomas an immunohistochemical study on 80 cases. Pathol Res Pract 204(9):625-631. doi: 10.1016/j.prp.2008.02.007
-
(2008)
Pathol Res Pract
, vol.204
, Issue.9
, pp. 625-631
-
-
Tirabosco, R.1
De Maglio, G.2
Skrap, M.3
Falconieri, G.4
Pizzolitto, S.5
-
236
-
-
47749133381
-
Copy number alterations of the Polycomb gene BMI1 in gliomas
-
10.1007/s00401-008-0376-0 18427816
-
Hayry V, Tanner M, Blom T, Tynninen O, Roselli A, Ollikainen M, Sariola H, Wartiovaara K, Nupponen NN (2008) Copy number alterations of the Polycomb gene BMI1 in gliomas. Acta Neuropathol 116(1):97-102. doi: 10.1007/s00401-008- 0376-0
-
(2008)
Acta Neuropathol
, vol.116
, Issue.1
, pp. 97-102
-
-
Hayry, V.1
Tanner, M.2
Blom, T.3
Tynninen, O.4
Roselli, A.5
Ollikainen, M.6
Sariola, H.7
Wartiovaara, K.8
Nupponen, N.N.9
-
237
-
-
67650727135
-
BMI1 sustains human glioblastoma multiforme stem cell renewal
-
10.1523/JNEUROSCI.0968-09.2009 1:CAS:528:DC%2BD1MXovFegtb8%3D 19605626
-
Abdouh M, Facchino S, Chatoo W, Balasingam V, Ferreira J, Bernier G (2009) BMI1 sustains human glioblastoma multiforme stem cell renewal. J Neurosci 29(28):8884-8896. doi: 10.1523/JNEUROSCI.0968-09.2009
-
(2009)
J Neurosci
, vol.29
, Issue.28
, pp. 8884-8896
-
-
Abdouh, M.1
Facchino, S.2
Chatoo, W.3
Balasingam, V.4
Ferreira, J.5
Bernier, G.6
-
238
-
-
57349121020
-
Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion
-
19048113 1345p following 1349
-
Michael LE, Westerman BA, Ermilov AN, Wang A, Ferris J, Liu J, Blom M, Ellison DW, van Lohuizen M, Dlugosz AA (2008) Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion. Neoplasia 10(12):1343-1349 1345p following 1349
-
(2008)
Neoplasia
, vol.10
, Issue.12
, pp. 1343-1349
-
-
Michael, L.E.1
Westerman, B.A.2
Ermilov, A.N.3
Wang, A.4
Ferris, J.5
Liu, J.6
Blom, M.7
Ellison, D.W.8
Van Lohuizen, M.9
Dlugosz, A.A.10
-
239
-
-
34347354307
-
Contribution of Polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis
-
10.1128/MCB.02244-06 1:CAS:528:DC%2BD2sXnsVWrtrs%3D 17452456
-
Wiederschain D, Chen L, Johnson B, Bettano K, Jackson D, Taraszka J, Wang YK, Jones MD, Morrissey M, Deeds J, Mosher R, Fordjour P, Lengauer C, Benson JD (2007) Contribution of Polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis. Mol Cell Biol 27(13):4968-4979. doi: 10.1128/MCB.02244-06
-
(2007)
Mol Cell Biol
, vol.27
, Issue.13
, pp. 4968-4979
-
-
Wiederschain, D.1
Chen, L.2
Johnson, B.3
Bettano, K.4
Jackson, D.5
Taraszka, J.6
Wang, Y.K.7
Jones, M.D.8
Morrissey, M.9
Deeds, J.10
Mosher, R.11
Fordjour, P.12
Lengauer, C.13
Benson, J.D.14
-
240
-
-
35148840173
-
Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma
-
10.1016/j.ccr.2007.08.032 1:CAS:528:DC%2BD2sXht1ais7zO 17936558
-
Bruggeman SW, Hulsman D, Tanger E, Buckle T, Blom M, Zevenhoven J, van Tellingen O, van Lohuizen M (2007) Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell 12(4):328-341. doi: 10.1016/j.ccr.2007.08.032
-
(2007)
Cancer Cell
, vol.12
, Issue.4
, pp. 328-341
-
-
Bruggeman, S.W.1
Hulsman, D.2
Tanger, E.3
Buckle, T.4
Blom, M.5
Zevenhoven, J.6
Van Tellingen, O.7
Van Lohuizen, M.8
-
241
-
-
35148884324
-
Bmi1 and cell of origin determinants of brain tumor phenotype
-
10.1016/j.ccr.2007.10.003 1:CAS:528:DC%2BD2sXht1ais7%2FE 17936553
-
Dirks P (2007) Bmi1 and cell of origin determinants of brain tumor phenotype. Cancer Cell 12(4):295-297. doi: 10.1016/j.ccr.2007.10.003
-
(2007)
Cancer Cell
, vol.12
, Issue.4
, pp. 295-297
-
-
Dirks, P.1
|