PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 12, 2009, Pages 4725-4730

  Li, Wenjing ^a   Ferguson, Brian J ^a,e   Khaled, Walid T ^a   Tevendale, Maxine ^a   Stingl, John ^a,f   Poli, Valeria ^b   Rich, Tina ^c   Salomoni, Paolo ^d   Watson, Christine J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF TURIN   (Italy)

^c Institute of Comparative Medicine   (United Kingdom)

^d MRC TOXICOLOGY UNIT   (United Kingdom)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Mammary gland; PML; Progenitor; Stat

Indexed keywords

PROMYELOCYTIC LEUKEMIA PROTEIN; STAT PROTEIN; NUCLEAR PROTEIN; PML PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COMPOSITION; CELL DIFFERENTIATION; CELL POPULATION; FLOW CYTOMETRY; IMMUNODETECTION; IN VIVO STUDY; LUNG ALVEOLUS CELL; MAMMARY GLAND; MOUSE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PREGNANCY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; STEM CELL; ANIMAL; CYTOLOGY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MORPHOGENESIS; UDDER;

MURINAE;

ANIMALS; CELL DIFFERENTIATION; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MAMMARY GLANDS, ANIMAL; MICE; MORPHOGENESIS; NUCLEAR PROTEINS; STAT TRANSCRIPTION FACTORS; STEM CELLS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 63849185620     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0807640106     Document Type: Article

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