Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum

Genes and Development

Volumn 14, Issue 8, 2000, Pages 994-1004

  Marino, Silvia ^a   Vooijs, Marc ^a   Van Der Gulden, Hanneke ^a   Jonkers, Jos ^a   Berns, Anton ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Astrocyte; Cre LoxP system; GFAP; Medulloblastoma; p53; Rb

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; PROTEIN P53; RECOMBINASE; RETINOBLASTOMA PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CEREBELLUM; CHILDHOOD CANCER; CONTROLLED STUDY; GENE INDUCTION; GENE MUTATION; GRANULE CELL; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; TUMOR SUPPRESSOR GENE;

ANIMALS; ASTROCYTES; BETA-GALACTOSIDASE; CEREBELLAR NEOPLASMS; CEREBELLUM; GENES, P53; GENES, RETINOBLASTOMA; GLIAL FIBRILLARY ACIDIC PROTEIN; IN SITU HYBRIDIZATION; INTEGRASES; MEDULLOBLASTOMA; MICE; MICE, MUTANT STRAINS; MUTATION; PLASMIDS; PROMOTER REGIONS (GENETICS); TISSUE DISTRIBUTION; TRANSCRIPTION, GENETIC; TRANSGENES; VIRAL PROTEINS;

ANIMALIA; RODENTIA;

EID: 0034656212     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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