-
1
-
-
0025173845
-
P53: Ocogene or antioncogene?
-
1 Lane D. P. and Benchimol S. (1990) p53: ocogene or antioncogene? Genes Dev. 4: 1-8
-
(1990)
Genes Dev.
, vol.4
, pp. 1-8
-
-
Lane, D.P.1
Benchimol, S.2
-
2
-
-
0025040233
-
Suppression of human colorectal carcinoma cell growth by wild-type p53
-
2 Baker S. J., Markowitz S., Fearon E. R., Willson J. K. V. and Vogelstein B. (1990) Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249: 912-915
-
(1990)
Science
, vol.249
, pp. 912-915
-
-
Baker, S.J.1
Markowitz, S.2
Fearon, E.R.3
Willson, J.K.V.4
Vogelstein, B.5
-
3
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
3 Greenblatt M. S., Hollstein M. and Harris C. C. (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54: 4855-4878
-
(1994)
Cancer Res.
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Hollstein, M.2
Harris, C.C.3
-
5
-
-
0028025564
-
How loops, β sheets, and α helices help us to understand p53
-
5 Prives C. (1994) How loops, β sheets, and α helices help us to understand p53. Cell 78: 543-546
-
(1994)
Cell
, vol.78
, pp. 543-546
-
-
Prives, C.1
-
7
-
-
0027315653
-
P53 and the li-fraumeni syndrome
-
7 Mulkin, D. (1993) p53 and the Li-Fraumeni syndrome. Cancer Genet. Cytogenet. 66: 83-92.
-
(1993)
Cancer Genet. Cytogenet.
, vol.66
, pp. 83-92
-
-
Mulkin, D.1
-
8
-
-
0021835959
-
Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by friend virus
-
8 Mowat M., Cheng A., Kimura N., Bernstein A. and Benchimol S. (1985) Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus. Nature 314: 633-636
-
(1985)
Nature
, vol.314
, pp. 633-636
-
-
Mowat, M.1
Cheng, A.2
Kimura, N.3
Bernstein, A.4
Benchimol, S.5
-
9
-
-
0026070065
-
Friend virus-induced erythroleukaemia and the multistage nature of cancer
-
9 Ben-David Y. and Bernstein A. (1991) Friend virus-induced erythroleukaemia and the multistage nature of cancer. Cell 66: 831-834
-
(1991)
Cell
, vol.66
, pp. 831-834
-
-
Ben-David, Y.1
Bernstein, A.2
-
10
-
-
0024431245
-
High incidence of lung, bone and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene
-
10 Lavigueur A., Maltby V., Mock D., Rossand J., Pawson T. and Bernstein A. (1989) High incidence of lung, bone and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Mol. Cell. Biol. 9: 3982-3991
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 3982-3991
-
-
Lavigueur, A.1
Maltby, V.2
Mock, D.3
Rossand, J.4
Pawson, T.5
Bernstein, A.6
-
11
-
-
0028033027
-
Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53-deficient mice
-
11 Lee J. M., Abrahamson J. L. A., Kandel R., Donehower L. A. and Bernstein A. (1994) Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53-deficient mice. Oncogene 9: 3731-3736
-
(1994)
Oncogene
, vol.9
, pp. 3731-3736
-
-
Lee, J.M.1
Abrahamson, J.L.A.2
Kandel, R.3
Donehower, L.A.A.4
Bernstein, A.5
-
12
-
-
0028842340
-
A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice
-
12 Harvey M., Vogel H., Morris D., Bradley A., Bernstein A. and Donehower L. A. (1995) A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice. Nature Genet. 9: 305-311
-
(1995)
Nature Genet.
, vol.9
, pp. 305-311
-
-
Harvey, M.1
Vogel, H.2
Morris, D.3
Bradley, A.4
Bernstein, A.5
Donehower, L.A.6
-
13
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
13 Donehower L. A., Harvey M., Slagle B. L., McArthur M. J., Montgomery C. A., Butel J. S. et al. (1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356: 215-221
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery, C.A.5
Butel, J.S.6
-
14
-
-
0027521657
-
Spontaneous and carcinogen-induced tumors in p53-deficient mice
-
14 Harvey M., McArthur M. J., Montgomery C. A., Butel J. S., Bradley A., Donehower L. A. et al. (1993) Spontaneous and carcinogen-induced tumors in p53-deficient mice. Nature Genet. 5: 225-229
-
(1993)
Nature Genet.
, vol.5
, pp. 225-229
-
-
Harvey, M.1
McArthur, M.J.2
Montgomery, C.A.3
Butel, J.S.4
Bradley, A.5
Donehower, L.A.6
-
15
-
-
0028862865
-
Effects of genetic background on tumorigenesis in p53-deficient mice
-
15 Donehower L. A., Harvey M., Vogel H., McArthur M. J., Montgomery J. C. A., Park S. H. et al. (1995) Effects of genetic background on tumorigenesis in p53-deficient mice. Mol. Carcinog. 14: 16-22
-
(1995)
Mol. Carcinog.
, vol.14
, pp. 16-22
-
-
Donehower, L.A.1
Harvey, M.2
Vogel, H.3
McArthur, M.J.4
Montgomery, J.C.A.5
Park, S.H.6
-
16
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
16 Jacks T., Remington L., Williams B. O., Schmitt E. M., Halachmi S., Bronson R. T. et al. (1994) Tumor spectrum analysis in p53-mutant mice. Curr. Biol. 4: 1-7
-
(1994)
Curr. Biol.
, vol.4
, pp. 1-7
-
-
Jacks, T.1
Remington, L.2
Williams, B.O.3
Schmitt, E.M.4
Halachmi, S.5
Bronson, R.T.6
-
17
-
-
0028176453
-
Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene
-
17 Purdie C. A., Harrison D. J., Peter A., Dobbie L., White S., Howie S. E. M. et al. (1994) Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene. Oncogene 9: 603-609
-
(1994)
Oncogene
, vol.9
, pp. 603-609
-
-
Purdie, C.A.1
Harrison, D.J.2
Peter, A.3
Dobbie, L.4
White, S.5
Howie, S.E.M.6
-
18
-
-
0030265337
-
The p53-deficient mouse: A model for basic and applied cancer studies
-
18 Donehower L. A. (1996) The p53-deficient mouse: a model for basic and applied cancer studies. Sem. Cancer Biol. 7: 269-278
-
(1996)
Sem. Cancer Biol.
, vol.7
, pp. 269-278
-
-
Donehower, L.A.1
-
19
-
-
0027226306
-
Genetic background alters the spectrum of tumors that develop in p53-deficient mice
-
19 Harvey M., McArthur M. J., Montgomery C. A. Jr., Bradley A. and Donehower L. A. (1993) Genetic background alters the spectrum of tumors that develop in p53-deficient mice. FASEB J. 7: 938-943
-
(1993)
FASEB J.
, vol.7
, pp. 938-943
-
-
Harvey, M.1
McArthur, M.J.2
Montgomery C.A., Jr.3
Bradley, A.4
Donehower, L.A.5
-
20
-
-
0027210981
-
Gain of function mutations in p53
-
20 Dittmer D., Pali S., Zambetti G., Chu S., Teresky A. K., Moore M. et al. (1993) Gain of function mutations in p53. Nature Genet. 4: 42-46
-
(1993)
Nature Genet.
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pali, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
-
21
-
-
0030941458
-
P53. The cellular gatekeeper for growth and division
-
21 Levine A. J. (1997) p53. the cellular gatekeeper for growth and division. Cell 88: 323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
22
-
-
0028168643
-
P53-deficient mice are extremely susceptible to radiation-induced tumorigenesis
-
22 Kemp C. J., Wheldon T. and Balmain A. (1994) p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis. Nature Genet. 8: 66-69
-
(1994)
Nature Genet.
, vol.8
, pp. 66-69
-
-
Kemp, C.J.1
Wheldon, T.2
Balmain, A.3
-
23
-
-
0026346885
-
Alterations of the p53 tumor suppressor gene during mouse skin tumor progression
-
23 Ruggeri B., Camano J., Goodrow T., DiRado M., Bianchi A., Trono D. et al. (1991) Alterations of the p53 tumor suppressor gene during mouse skin tumor progression. Cancer Res. 51: 6615-6621
-
(1991)
Cancer Res.
, vol.51
, pp. 6615-6621
-
-
Ruggeri, B.1
Camano, J.2
Goodrow, T.3
DiRado, M.4
Bianchi, A.5
Trono, D.6
-
24
-
-
0027500049
-
Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene
-
24 Ruggeri B., DiRado M., Zhang S. Y., Bauer B., Goodrow T. and Klein-Santo A. J. P. (1993) Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc. Natl. Acad. Sci. USA 90: 1013-1017
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1013-1017
-
-
Ruggeri, B.1
DiRado, M.2
Zhang, S.Y.3
Bauer, B.4
Goodrow, T.5
Klein-Santo, A.J.P.6
-
25
-
-
0027203921
-
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
-
25 Kemp C. J., Donehower L. A., Bradley A. and Balmain A. (1993) Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 74: 813-822
-
(1993)
Cell
, vol.74
, pp. 813-822
-
-
Kemp, C.J.1
Donehower, L.A.2
Bradley, A.3
Balmain, A.4
-
26
-
-
0026480247
-
Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin
-
26 Kress S., Sutter C., Strickland P. T., Mukhtar H., Schweizer J. and Schwartz M. (1992) Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin. Cancer Res. 52: 6400-6403
-
(1992)
Cancer Res.
, vol.52
, pp. 6400-6403
-
-
Kress, S.1
Sutter, C.2
Strickland, P.T.3
Mukhtar, H.4
Schweizer, J.5
Schwartz, M.6
-
27
-
-
0027214013
-
High frequency of p53 mutations in ultraviolet radiation-induced murine skin tumors: Evidence for strand bias and tumor heterogeneity
-
27 Kanjilal S., Pierceall W. E., Cummings K. K., Kripke M. L. and Ananthaswamy H. N. (1993) High frequency of p53 mutations in ultraviolet radiation-induced murine skin tumors: evidence for strand bias and tumor heterogeneity. Cancer Res. 53: 2961-2964
-
(1993)
Cancer Res.
, vol.53
, pp. 2961-2964
-
-
Kanjilal, S.1
Pierceall, W.E.2
Cummings, K.K.3
Kripke, M.L.4
Ananthaswamy, H.N.5
-
28
-
-
0029026594
-
Frequent p53 alterations but now incidence of ras mutations in UV-B-induced skin tumors of hairless mice
-
28 van Kranen H. J., de Gruijl F. R., de Vries A., Sontag Y., Wester P. W., Senden H. C. M. et al. (1995) Frequent p53 alterations but now incidence of ras mutations in UV-B-induced skin tumors of hairless mice. Carcinogenesis 16: 1141-1147
-
(1995)
Carcinogenesis
, vol.16
, pp. 1141-1147
-
-
Van Kranen, H.J.1
De Gruijl, F.R.2
De Vries, A.3
Sontag, Y.4
Wester, P.W.5
Senden, H.C.M.6
-
29
-
-
0031417965
-
The role of UV-B light in skin carcinogenesis throught the analysis of p53 mutations in squamous cell carcinomas of hairless mice
-
29 Dumaz N., van Kranen H. J., de Vries A., Berg R. J. W., Wester P. W., van Kreijl C. F. et al. (1997) The role of UV-B light in skin carcinogenesis throught the analysis of p53 mutations in squamous cell carcinomas of hairless mice. Carcino-genesis 18: 897-904
-
(1997)
Carcino-genesis
, vol.18
, pp. 897-904
-
-
Dumaz, N.1
Van Kranen, H.J.2
De Vries, A.3
Berg, R.J.W.4
Wester, P.W.5
Van Kreijl, C.F.6
-
30
-
-
0029071480
-
Ultraviolet radiation induction of squamous cell carcinomas in p53 transgenic mice
-
30 Li G., Ho V. C., Berean K. and Tron V. A. (1995) Ultraviolet radiation induction of squamous cell carcinomas in p53 transgenic mice. Cancer Res. 55: 2070-2074
-
(1995)
Cancer Res.
, vol.55
, pp. 2070-2074
-
-
Li, G.1
Ho, V.C.2
Berean, K.3
Tron, V.A.4
-
31
-
-
0031933682
-
Induction of squamous cell carcinoma in p53-deficient mice after ultraviolet irradiation
-
31 Li G., Tron V. and Ho V. (1998) Induction of squamous cell carcinoma in p53-deficient mice after ultraviolet irradiation. J. Invest. Dermatol. 110: 72-75
-
(1998)
J. Invest. Dermatol.
, vol.110
, pp. 72-75
-
-
Li, G.1
Tron, V.2
Ho, V.3
-
32
-
-
0030968938
-
Sunlight and skin cancer: Inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens
-
32 Ananthaswamy H. N., Louglin S. M., Cox P., Evans R. L., Ullrich S. E. and Kripke M. L. (1997) Sunlight and skin cancer: inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens. Nature Med. 5: 510-514
-
(1997)
Nature Med.
, vol.5
, pp. 510-514
-
-
Ananthaswamy, H.N.1
Louglin, S.M.2
Cox, P.3
Evans, R.L.4
Ullrich, S.E.5
Kripke, M.L.6
-
33
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
33 Ziegler A., Jonason A. S., Leffell D. J., Simon J. A., Sharma H. W., Limmelman J. et al. (1994) Sunburn and p53 in the onset of skin cancer. Nature 372: 773-776
-
(1994)
Nature
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
Jonason, A.S.2
Leffell, D.J.3
Simon, J.A.4
Sharma, H.W.5
Limmelman, J.6
-
34
-
-
0028286960
-
Screening for p53 mutations in C3H/He mouse liver tumors derived spontaneously or induced with diethylnitrosamine or phenobarbitone
-
34 Rumsby P. C., Davies M. J. and Evans J. G. (1994) Screening for p53 mutations in C3H/He mouse liver tumors derived spontaneously or induced with diethylnitrosamine or phenobarbitone. Mol. Carcinog. 9: 71-75
-
(1994)
Mol. Carcinog.
, vol.9
, pp. 71-75
-
-
Rumsby, P.C.1
Davies, M.J.2
Evans, J.G.3
-
35
-
-
0028838588
-
K-ras mutations in lung tumors from A/J and A/JXTSG-p53 F1 mice treated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothicoyanate
-
35 Matzinger S. A., Crist K. A., Stoner G. D., Anderson M. W., Pereira M. A., Steele V. E. et al. (1995) K-ras mutations in lung tumors from A/J and A/JXTSG-p53 F1 mice treated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothicoyanate. Carcinogenesis 16: 2487-2492
-
(1995)
Carcinogenesis
, vol.16
, pp. 2487-2492
-
-
Matzinger, S.A.1
Crist, K.A.2
Stoner, G.D.3
Anderson, M.W.4
Pereira, M.A.5
Steele, V.E.6
-
36
-
-
0028335432
-
Infrequent p53 mutations in 7, 12-dimethylbenz(a)anthracene-induced mammary tumors in BALB/c and p53 hemizygous mice
-
36 Jerry D. J., Butel J. S., Donehower L. A., Paulson E. J., Cochran C., Wiseman R. W. et al. (1994) Infrequent p53 mutations in 7, 12-dimethylbenz(a)anthracene-induced mammary tumors in BALB/c and p53 hemizygous mice. Mol. Carcinog. 9: 175-183
-
(1994)
Mol. Carcinog.
, vol.9
, pp. 175-183
-
-
Jerry, D.J.1
Butel, J.S.2
Donehower, L.A.3
Paulson, E.J.4
Cochran, C.5
Wiseman, R.W.6
-
37
-
-
0028936624
-
Hepatocarcinogenesis in p53-deficient mice
-
37 Kemp C. J. (1995) Hepatocarcinogenesis in p53-deficient mice. Mol. Carcinog. 12: 132-136
-
(1995)
Mol. Carcinog.
, vol.12
, pp. 132-136
-
-
Kemp, C.J.1
-
38
-
-
0029855293
-
Evaluation of transgenic mouse bioassays for identifying carcinogens and noncarcinogens
-
38 Tennant R. W., Spalding J. and French J. E. (1996) Evaluation of transgenic mouse bioassays for identifying carcinogens and noncarcinogens. Mutat. Res. 365: 119-127
-
(1996)
Mutat. Res.
, vol.365
, pp. 119-127
-
-
Tennant, R.W.1
Spalding, J.2
French, J.E.3
-
39
-
-
0028237041
-
Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice
-
39 Hursting S. D., Perkins S. N. and Phang J. M. (1994) Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice. Proc. Natl. Acad. Sci. USA 91: 7036-7040
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7036-7040
-
-
Hursting, S.D.1
Perkins, S.N.2
Phang, J.M.3
-
40
-
-
0030746765
-
Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice
-
40 Hursting S. D., Perkins S. N., Brown C. C., Haines D. C. and Phang J. M. (1997) Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice. Cancer Res. 57: 2843-2846
-
(1997)
Cancer Res.
, vol.57
, pp. 2843-2846
-
-
Hursting, S.D.1
Perkins, S.N.2
Brown, C.C.3
Haines, D.C.4
Phang, J.M.5
-
41
-
-
0029126002
-
Chemoprevention of spontaneous tumorigenesis in p53-knockout mice
-
41 Hursting S. D., Perkins S. N., Haines D. C., Ward J. M. and Phang J. M. (1995) Chemoprevention of spontaneous tumorigenesis in p53-knockout mice. Cancer Res. 55: 3949-3953
-
(1995)
Cancer Res.
, vol.55
, pp. 3949-3953
-
-
Hursting, S.D.1
Perkins, S.N.2
Haines, D.C.3
Ward, J.M.4
Phang, J.M.5
-
42
-
-
0027319521
-
P53 is required for radiation-induced apoptosis in mouse thymocytes
-
42 Lowe S. W., Schmitt E. S., Smith S. W., Osborne B. A. and Jacks T. (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.S.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
43
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
43 Clarke A. R., Purdie C. A., Harrison D. J., Morris R. G., Bird C. C., Hooper M. L. et al. (1993) Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362: 849-852
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
-
44
-
-
0027970838
-
Chromosomal translocations in human cancer
-
44 Rabbitts T. H. (1994) Chromosomal translocations in human cancer. Nature 372: 143-149
-
(1994)
Nature
, vol.372
, pp. 143-149
-
-
Rabbitts, T.H.1
-
45
-
-
0025811882
-
The scid mouse mutant: Definition, characterization, and potential uses
-
45 Bosma M. and Carroll A. (1991) The scid mouse mutant: definition, characterization, and potential uses. Annu. Rev. Immunol. 9: 323-350
-
(1991)
Annu. Rev. Immunol.
, vol.9
, pp. 323-350
-
-
Bosma, M.1
Carroll, A.2
-
46
-
-
0029881698
-
P53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes
-
46 Bogue M. A., Zhu C., Aguilar-Cordova F., Donehower L. A., Roth D. B. et al. (1996) p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes. Genes Dev. 10: 553-565
-
(1996)
Genes Dev.
, vol.10
, pp. 553-565
-
-
Bogue, M.A.1
Zhu, C.2
Aguilar-Cordova, F.3
Donehower, L.A.4
Roth, D.B.5
-
47
-
-
0029858143
-
V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors
-
47 Guidos C. J., Williams C. J., Grandal I., Knowles G., Huang M. T. F. and Danska J. S. (1996) V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. Genes Dev. 10: 2038-2054
-
(1996)
Genes Dev.
, vol.10
, pp. 2038-2054
-
-
Guidos, C.J.1
Williams, C.J.2
Grandal, I.3
Knowles, G.4
Huang, M.T.F.5
Danska, J.S.6
-
48
-
-
0029858044
-
Mutations in the p53 and SCID genes cooperate in tumorigenesis
-
48 Nacht M., Strasser A., Chan Y. R., Harris A. W., Schlissel M., Bronson R. T. et al. (1996) Mutations in the p53 and SCID genes cooperate in tumorigenesis. Genes Dev. 10: 2055-2066
-
(1996)
Genes Dev.
, vol.10
, pp. 2055-2066
-
-
Nacht, M.1
Strasser, A.2
Chan, Y.R.3
Harris, A.W.4
Schlissel, M.5
Bronson, R.T.6
-
49
-
-
0031869669
-
No requirement for V(D)J recombination in p53-deficient thymic lymphoma
-
49 Liao M. J., Zhang X. X., Hill R., Gao J., Qumsiyeh M. B., Nichole W. et al. (1998) No requirement for V(D)J recombination in p53-deficient thymic lymphoma. Mol. Cell. Biol. 18: 3495-3501
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3495-3501
-
-
Liao, M.J.1
Zhang, X.X.2
Hill, R.3
Gao, J.4
Qumsiyeh, M.B.5
Nichole, W.6
-
50
-
-
0031992186
-
V(D)J recombination is not required for the development of lymphoma in p53-deficient mice
-
50 Nacht M. and Jacks T. (1998) V(D)J recombination is not required for the development of lymphoma in p53-deficient mice. Cell Growth Differ. 9: 131-138
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 131-138
-
-
Nacht, M.1
Jacks, T.2
-
51
-
-
0026355290
-
Mutant p53, EGF receptor and c-erbB-2 expression in human breast cancer
-
51 Horak E., Smith K., Bromley L., Le Jeune S., Greenall M., Lane D. et al. (1991) Mutant p53, EGF receptor and c-erbB-2 expression in human breast cancer. Oncogene 6: 2277-2284
-
(1991)
Oncogene
, vol.6
, pp. 2277-2284
-
-
Horak, E.1
Smith, K.2
Bromley, L.3
Le Jeune, S.4
Greenall, M.5
Lane, D.6
-
52
-
-
0026472124
-
Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
-
52 Guy S. T., Webster M. A., Schaller M., Parsons T. J., Cardiff R. D. and Muller W. J. (1992) Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc. Natl. Acad. Sci. USA 89: 10578-10582
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10578-10582
-
-
Guy, S.T.1
Webster, M.A.2
Schaller, M.3
Parsons, T.J.4
Cardiff, R.D.5
Muller, W.J.6
-
53
-
-
0030946970
-
Neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice
-
53 Li B., Rosen J. M., McMenamin-Blano J., Muller W. J. and Perkins A. S. (1997) neu/ERBB2 Cooperates with p53-172H during mammary tumorigenesis in transgenic mice. Mol. Cell. Biol. 17: 3155-3163
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3155-3163
-
-
Li, B.1
Rosen, J.M.2
McMenamin-Blano, J.3
Muller, W.J.4
Perkins, A.S.5
-
54
-
-
0024162530
-
Expression of the int-1 gene in transgenic mice is associated with mammary hyperplasia and adenocarcinomas in male and female mice
-
54 Tsukamoto A. S., Grosschedl R., Guman R. C., Parslow T. and Varmus H. E. (1988) Expression of the int-1 gene in transgenic mice is associated with mammary hyperplasia and adenocarcinomas in male and female mice. Cell 55: 619-625
-
(1988)
Cell
, vol.55
, pp. 619-625
-
-
Tsukamoto, A.S.1
Grosschedl, R.2
Guman, R.C.3
Parslow, T.4
Varmus, H.E.5
-
55
-
-
0028951801
-
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability
-
55 Donehower L. A., Godley L. A., Aldaz C. M., Pyle R., Shi Y.-P., Pinkel D. et al. (1995) Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes Dev. 9: 882-895
-
(1995)
Genes Dev.
, vol.9
, pp. 882-895
-
-
Donehower, L.A.1
Godley, L.A.2
Aldaz, C.M.3
Pyle, R.4
Shi, Y.-P.5
Pinkel, D.6
-
56
-
-
0030812202
-
Absence of p53 in a mouse mammary tumour model promotes tumor cell proliferation with out affecting apoptosis
-
56 Jones J., Attardi L., Godley L. A., Laucirica R., Medina D., Jacks T. et al. (1997) Absence of p53 in a mouse mammary tumour model promotes tumor cell proliferation with out affecting apoptosis. Cell Growth Differ. 8: 829-838
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 829-838
-
-
Jones, J.1
Attardi, L.2
Godley, L.A.3
Laucirica, R.4
Medina, D.5
Jacks, T.6
-
57
-
-
0031012977
-
Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53
-
57 Hundley J. F., Koester S. K., Troyer D. A., Hilsenbeck S. G., Subler M. A. and Windle J. J. (1997) Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53. Mol. Cell. Biol. 17: 723-731
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 723-731
-
-
Hundley, J.F.1
Koester, S.K.2
Troyer, D.A.3
Hilsenbeck, S.G.4
Subler, M.A.5
Windle, J.J.6
-
58
-
-
0029060361
-
Synergy between a human c-myc transgene and p53 null genotype in murine thymic lymphomas: Contrasting effects of homozygous and heterozygous p53 loss
-
58 Blyth K., Terry A., O'Hara M., Baxter E. W., Campbell M., Stewart M. et al. (1995) Synergy between a human c-myc transgene and p53 null genotype in murine thymic lymphomas: contrasting effects of homozygous and heterozygous p53 loss. Oncogene 10: 1717-1723
-
(1995)
Oncogene
, vol.10
, pp. 1717-1723
-
-
Blyth, K.1
Terry, A.2
O'Hara, M.3
Baxter, E.W.4
Campbell, M.5
Stewart, M.6
-
59
-
-
0029134878
-
Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis
-
59 Hsu B., Marin M. C., El-Nagger A. K., Stephens L. C., Brisbay S. and McDonnell T. J. (1995) Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis. Oncogene 11: 175-179
-
(1995)
Oncogene
, vol.11
, pp. 175-179
-
-
Hsu, B.1
Marin, M.C.2
El-Nagger, A.K.3
Stephens, L.C.4
Brisbay, S.5
McDonnell, T.J.6
-
60
-
-
0029135433
-
The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice
-
60 Elson A., Deng C., Campos-Torres J., Donehower L. A. and Leder P. (1995) The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice. Oncogene 11: 181-190
-
(1995)
Oncogene
, vol.11
, pp. 181-190
-
-
Elson, A.1
Deng, C.2
Campos-Torres, J.3
Donehower, L.A.4
Leder, P.5
-
61
-
-
0029844127
-
T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice
-
61 Condorelli G. L., Facchiano F., Valtieri M., Proietti F., Vitelli L., Lulli K. et al. (1996) T-Cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice. Cancer Res. 56: 5113-5119
-
(1996)
Cancer Res.
, vol.56
, pp. 5113-5119
-
-
Condorelli, G.L.1
Facchiano, F.2
Valtieri, M.3
Proietti, F.4
Vitelli, L.5
Lulli, K.6
-
62
-
-
0031454577
-
The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice
-
62 Curtis D. J., Robb L., Strasser A. and Begley C. G. (1997) The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice. Oncogene 15: 2975-2983
-
(1997)
Oncogene
, vol.15
, pp. 2975-2983
-
-
Curtis, D.J.1
Robb, L.2
Strasser, A.3
Begley, C.G.4
-
63
-
-
0028020522
-
Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis
-
63 Marin M. C., Hsu B., Meyn R. E., Donehower L. A., El-Naggar A. K. and McDonnell T. (1994) Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis. Oncogene 9: 3107-3112
-
(1994)
Oncogene
, vol.9
, pp. 3107-3112
-
-
Marin, M.C.1
Hsu, B.2
Meyn, R.E.3
Donehower, L.A.4
El-Naggar, A.K.5
McDonnell, T.6
-
64
-
-
0028136594
-
Cooperative tumorigenic effects of germline mutations in Rb and p53
-
64 Williams B. O., Remington L., Bronson R. T., Mukai S., Albert D. M., Dryja T. et al. (1994) Cooperative tumorigenic effects of germline mutations in Rb and p53. Nature. Genet. 7: 480-484
-
(1994)
Nature. Genet.
, vol.7
, pp. 480-484
-
-
Williams, B.O.1
Remington, L.2
Bronson, R.T.3
Mukai, S.4
Albert, D.M.5
Dryja, T.6
-
65
-
-
0028376386
-
Analysis of viral-host protein interactions and tumorigenesis in transgenic mice
-
65 Van Dyke T. A. (1994) Analysis of viral-host protein interactions and tumorigenesis in transgenic mice. Sem. Cancer. Biol. 5: 106.1-106.14
-
(1994)
Sem. Cancer. Biol.
, vol.5
, pp. 1061-10614
-
-
Van Dyke, T.A.1
-
66
-
-
0028937476
-
Mice deficient in both p53 and Rb develop tumours primarily of endocrine origin
-
66 Harvey M., Vogel H., Lee E. Y., Bradley A. and Donehower L. A. (1995) Mice deficient in both p53 and Rb develop tumours primarily of endocrine origin. Cancer Res. 55: 1146-1151
-
(1995)
Cancer Res.
, vol.55
, pp. 1146-1151
-
-
Harvey, M.1
Vogel, H.2
Lee, E.Y.3
Bradley, A.4
Donehower, L.A.5
-
67
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
67 Fearon E. R. and Vogelstein B. (1990) A genetic model for colorectal tumorigenesis. Cell 61: 759-767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
68
-
-
0028792347
-
Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy
-
68 Clarke A. R., Cummings M. C. and Harrison D. J. (1995) Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy. Oncogene 11: 1913-1920
-
(1995)
Oncogene
, vol.11
, pp. 1913-1920
-
-
Clarke, A.R.1
Cummings, M.C.2
Harrison, D.J.3
-
69
-
-
0032522603
-
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors
-
69 McClatchey A. I., Saotome I., Mercer K., Crowley D., Gusella J. F., Bronson R. T. et al. (1998) Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors. Genes. Dev. 12: 1121-1133
-
(1998)
Genes. Dev.
, vol.12
, pp. 1121-1133
-
-
McClatchey, A.I.1
Saotome, I.2
Mercer, K.3
Crowley, D.4
Gusella, J.F.5
Bronson, R.T.6
-
70
-
-
0030879563
-
Atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity
-
70 Westphal C. H., Rowan S., Schmaltz C., Elson A., Fisher D. E. and Leder P. (1997) atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity. Nature Genet. 16: 397-401
-
(1997)
Nature Genet.
, vol.16
, pp. 397-401
-
-
Westphal, C.H.1
Rowan, S.2
Schmaltz, C.3
Elson, A.4
Fisher, D.E.5
Leder, P.6
-
71
-
-
0030814494
-
Female embryonic lethality in mice nullizygous for both Msh2 and p53
-
71 Cranston A., Bocker T., Retimair A., Palazzo J., Wilson T., Mak T. et al. (1997) Female embryonic lethality in mice nullizygous for both Msh2 and p53. Nature Genet. 17: 114-118
-
(1997)
Nature Genet.
, vol.17
, pp. 114-118
-
-
Cranston, A.1
Bocker, T.2
Retimair, A.3
Palazzo, J.4
Wilson, T.5
Mak, T.6
-
72
-
-
0030480945
-
Synergistic interactions between XPC and p53 mutations in double-mutant mice: Neural tube abnormalities and accelerated UV radiation-induced skin cancer
-
72 Cheo D. L., Meira L. B., Hammer R. E., Burns D. K., Doughty A. T. B. and Friedber E. C. (1996) Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer. Curr. Biol. 6: 1691-1694
-
(1996)
Curr. Biol.
, vol.6
, pp. 1691-1694
-
-
Cheo, D.L.1
Meira, L.B.2
Hammer, R.E.3
Burns, D.K.4
Doughty, A.T.B.5
Friedber, E.C.6
-
73
-
-
0028169994
-
P53-dependent apoptosis suppresses tumor growth and progression in vivo
-
73 Symonds H., Krall L., Remington L., Saenz-Robles M., Lowe S., Jacks T. et al. (1994) p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78: 703-711
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
Saenz-Robles, M.4
Lowe, S.5
Jacks, T.6
-
74
-
-
0029916320
-
Tissue-specific inactivation of p53 tumor suppression in the mouse
-
74 Bowman T., Symonds H., Gu L., Yin C., Oren M. and Van Dyke T. (1996) Tissue-specific inactivation of p53 tumor suppression in the mouse. Genes Dev. 10: 826-835
-
(1996)
Genes Dev.
, vol.10
, pp. 826-835
-
-
Bowman, T.1
Symonds, H.2
Gu, L.3
Yin, C.4
Oren, M.5
Van Dyke, T.6
-
75
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
75 Miyashita T., Krajewski S., Krajewska M., Wang H. G., Lin H. K., Liebermann D. A. et al. (1994) Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9: 1799-1805
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
-
76
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
76 Miyashita T. and Reed J. C. (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
77
-
-
0031038137
-
Bax suppresses tumorigenesis and stimulates apoptosis in vivo
-
77 Yin C., Knudson C. M., Korsmeyer S. J. and Van Dyke T. (1997) Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature 385: 637-640
-
(1997)
Nature
, vol.385
, pp. 637-640
-
-
Yin, C.1
Knudson, C.M.2
Korsmeyer, S.J.3
Van Dyke, T.4
-
78
-
-
0028227260
-
Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
-
78 Howes K. A., Ransom N., Papermaster D. S., Lasudry J. G. H., Albert D. M. and Windle J. J. (1994) Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev. 8: 1300-1310
-
(1994)
Genes Dev.
, vol.8
, pp. 1300-1310
-
-
Howes, K.A.1
Ransom, N.2
Papermaster, D.S.3
Lasudry, J.G.H.4
Albert, D.M.5
Windle, J.J.6
-
79
-
-
0028334011
-
Altered cell-cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
-
79 Pan H. and Griep A. (1994) Altered cell-cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev. 8: 1285-1299
-
(1994)
Genes Dev.
, vol.8
, pp. 1285-1299
-
-
Pan, H.1
Griep, A.2
-
80
-
-
0029093605
-
Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
-
80 Pan H. and Griep A. E. (1995) Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev. 9: 2157-2169
-
(1995)
Genes Dev.
, vol.9
, pp. 2157-2169
-
-
Pan, H.1
Griep, A.E.2
-
81
-
-
0029881977
-
Abnormal centrosome amplification in the absence of p53
-
81 Fukasawa K., Choi T., Kuriyama R., Rulong S. and Vande Woude G. F. (1996) Abnormal centrosome amplification in the absence of p53. Science 271: 1744-1747
-
(1996)
Science
, vol.271
, pp. 1744-1747
-
-
Fukasawa, K.1
Choi, T.2
Kuriyama, R.3
Rulong, S.4
Vande Woude, G.F.5
-
82
-
-
0027179908
-
In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice
-
82 Harvey M., Sands A. T., Weiss R. S., Hegi M. E., Wiseman R. W., Pantazis P. et al. (1993) In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice. Oncogene 8: 2457-2467
-
(1993)
Oncogene
, vol.8
, pp. 2457-2467
-
-
Harvey, M.1
Sands, A.T.2
Weiss, R.S.3
Hegi, M.E.4
Wiseman, R.W.5
Pantazis, P.6
-
83
-
-
0027251720
-
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
-
83 Debbas M. and White E. (1993) Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev. 7: 546-554
-
(1993)
Genes Dev.
, vol.7
, pp. 546-554
-
-
Debbas, M.1
White, E.2
-
84
-
-
0027262606
-
Stabilization of the p53 tumor suppressor is induced by adenovirus-5 E1A and accompanies apoptosis
-
84 Lowe S. W. and Ruley H. E. (1993) Stabilization of the p53 tumor suppressor is induced by adenovirus-5 E1A and accompanies apoptosis. Genes Dev. 7: 535-545
-
(1993)
Genes Dev.
, vol.7
, pp. 535-545
-
-
Lowe, S.W.1
Ruley, H.E.2
-
85
-
-
0028171968
-
Mediation of c-myc-induced apoptosis by p53
-
85 Hermeking H. and Eick D. (1994) Mediation of c-myc-induced apoptosis by p53. Science 265: 2091-2093
-
(1994)
Science
, vol.265
, pp. 2091-2093
-
-
Hermeking, H.1
Eick, D.2
-
86
-
-
0028034199
-
Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell-cycle arrest and the ability of p53 to induce p21 waf1/cip1
-
86 Wagner A. J., Kokontis J. M. and Hay N. (1994) Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell-cycle arrest and the ability of p53 to induce p21 waf1/cip1. Genes Dev. 8: 2817-2830
-
(1994)
Genes Dev.
, vol.8
, pp. 2817-2830
-
-
Wagner, A.J.1
Kokontis, J.M.2
Hay, N.3
-
87
-
-
0029910628
-
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
-
87 Macleod K., Hu Y. and Jacks T. (1996) Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J. 15: 6178-6188
-
(1996)
EMBO J.
, vol.15
, pp. 6178-6188
-
-
Macleod, K.1
Hu, Y.2
Jacks, T.3
-
88
-
-
0030791113
-
Involvement of p53 in cell differentiation and development
-
88 Almog N. and Rotter V. (1997) Involvement of p53 in cell differentiation and development. Biochem. Biophys. Acta 1333: F1-F27
-
(1997)
Biochem. Biophys. Acta
, vol.1333
-
-
Almog, N.1
Rotter, V.2
|