P53 expression and regulation by NMDA receptors in the developing rat brain

Journal of Neuroscience Research

Volumn 56, Issue 4, 1999, Pages 427-440

  Poulaki, Vassiliki ^a,b,c   Benekou, A ^a   Bozas, E ^a   Bolaris, S ^a   Stylianopoulou, F ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b NATIONAL CANCER INSTITUTE   (United States)

^c Bldg 10 ^*  (United States)

Author keywords

Brain; Development; NMDA receptors; P53

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; EMBRYO; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; NEUROMODULATION; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; APOPTOSIS; BLOTTING, NORTHERN; BRAIN; CELL NUCLEUS; CYTOPLASM; DIZOCILPINE MALEATE; EPITHELIUM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, P53; IMMUNOLOGIC TECHNIQUES; IN SITU NICK-END LABELING; MALE; N-METHYLASPARTATE; NEURONS; PHOSPHORYLATION; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0033562491     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990515)56:4<427::AID-JNR10>3.0.CO;2-J     Document Type: Article

References (33)

1. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Analyt Biochem 162:156-159.
2. Copp AJ, Brook FA, Estibeiro J, Shum AS, Cockroft DL. 1990. The embryonic development of mammalian neural tube defects. Prog Neurobiol 35:363-403.
3. Cunningham TJ. 1982. Naturally occurring neuron death and its regulation by developing neural pathways. Int Rev Cytol 74:163-186.
4. Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, Butel JS, Bradley A. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356:215-221.
5. Eizenberg O, Faber-Elman A, Gottlieb E, Oren M, Rotter V, Schwartz M. 1996. P53 plays a regulatory role in differentiation and apoptosis of central nervous system. Mol Cell Biol 16:5178-5185.
6. Ferrer I, Soriano E, del Rio JA, Alcantara S, Auladell C. 1992. Cell death and removal in the cerebral cortex during development. Prog Neurobiol 39:1-43.
7. Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Bukowska K, Bursch W, Schulte-Hermann R. 1995. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 21:1465-1468.
8. Haas-Kogan D.A., Dazin P, Hu L, Deen DF, Israel MA. 1996. P53 independent apoptosis: a mechanism of radiation-induced cell death of glioblastoma cells. Cancer J Sci Am Mar 2:114.
9. Hughes PE, Alexi T, Yoshida T, Schreiber SS, Knusel B. 1996. Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes BAX and GADD-45 in brain areas showing DNA fragmentation. Neuroscience 74:1143-1160.
10. Ibrahim AP, Gallimore PH, Grand RJ. 1997. The expression of mdm-2 and other p53-regulated proteins in the tissues of the developing rat. Biochim Biophys Acta 1350:306-316.
11. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. 1991. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 51:6304-6311.
12. Kitraki E, Bozas E, Philippidis H, Stylianopoulou F. 1993. Aging-related changes in IGF-II and c-fos gene expression in the rat brain. Int J Dev Neurosci 11:1-9.
13. Kleinschmidt A, Bear MF, Singer W. 1987. Blockade of NMDA receptors disrupts experience-dependent plasticity of kitten striate cortex. Science 238:355-358.
14. Komarova EA, Chernov MV, Franks R, Wang K, Armin G, Zelnick CR, Chin DM, Bacus SS, Stark GR, Gudkov AV. 1997. Trangenic mice with p53-responsive lacZ: P53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo. EMBO J 16:1391-1400.
15. Krueger B, Burne J, Raff M. 1995. Evidence for large-scale astrocyte death in the developing cerebellum. J Neurosci 15:3366-3374.
16. Li Y, Chopp M, Zhang ZG, Zaloga C, Niewenhuis L, Gautam S. 1994. P53-immunoreactive protein and p53 mRNA exrpression after transient middle cerebral artery occlusion in rats. Stroke 25:849-855.
17. Louis JM, McFarland VW, May P, Mora PT. 1988. The phosphoprotein p53 is down-regulated post-trancriptionally during embryogenesis in vertebrates. Biochim Biophys Acta 950:395-402.
18. Macleod KF, Hu Y, Jacks T. 1996. Loss of RB activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J 15:6178-6188.
19. Mundle SD, Gao XZ, Khan S, Gregory SA, Preisler HD, Raza A. 1995. Two in situ labeling techniques reveal different patterns of DNA fragmentation during spontaneous apoptosis in vivo and induced apoptosis in vitro. Anticancer Res 15:1895-1904.
20. Oppenheim RW. 1991. Cell death during development of the nervous system. Ann Rev Neurosci 14:453-501.
21. Portera-Cailliau C, Price D, Martin L. 1997. Excitotoxic neuronal death in the immature brain is an apoptosis-necrosis continuum. J Comp Neurol 378:70-87.
22. Rogel A, Popliker M, Webb CG, Oren M. 1985. p53 cellular tumor antigen: Analysis of mRNA levels in normal adult tissues, embryos, and tumors. Mol Cell Biol 5:2851-2855.
23. Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T. 1995. A subset of p53-deficient embryos exhibit exencephaly. Nat Genet 10:175-180.
24. Sakhi S, Sun N, Wing LL, Mehta P, Schreiber SS. 1996. Nuclear accumulation of p53 protein following kainic acid-induced seizures. Neuroreport 7:493-496.
25. Sakhi S, Bruce A, Sun N, Tocco G, Baudry M, Schreiber SS. 1997. Induction of tumor suppressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment. Exp Neurol 145:81-88.
26. Schmid P, Lorenz A, Hameister H, Montenarh M. 1991. Expression of p53 during mouse embryogenesis. Development 113: 857-865.
27. Schowalter DB, Sommer SS. 1989. The generation of radiolabeled DNA and RNA probes with polymerase chain reaction. Anal Biochem 177:90-94.
28. Schwartz LM. 1991. The role of cell death genes during development. Bioessays 13:389-395.
29. Stuart E, Haffner R, Oren M, Gruss P. 1995. Loss of p53 function through PAX-mediated trancriptional repression. EMBO J 14: 5638-5645.
30. Vancutsem PM, Lazarus P, Williams GM. 1994. Frequent and specific mutations of the rat p53 gene in hepatocarcinomas induced by tamoxifen. Cancer Res 54: 3864-3867.
31. Volgestein, B. Kinzler KW. 1992. P53 function and dysfunction. Cell 70:523-526.
32. Watanabe M. 1997. Developmental dynamics of gene expression for NMDA receptor channel. In Monaghan DT, Wenthold RJ, editors. The ionotropic glutamate receptors. Totowa, NJ: Humana Press. p 189.
33. Wlodarczyk BC, Craig JC, Bennett GD, Calvin JA, Finnell RH. 1996. Valproic acid-induced changes in gene expression during neurulation in a mouse model.Teratology 54:284-297.