Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas

Nature

Volumn 428, Issue 6980, 2004, Pages 337-341

  Leung, Carly ^a   Lingbeek, Merel ^b   Shakhova, Olga ^a   Liu, James ^a   Tanger, Ellen ^b   Saremaslani, Parvin ^a   Van Lohuizen, Maarten ^b   Marino, Silvia ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; CELL CULTURE; GENES; TUMORS;

CLONAL EXPANSIONS; TUMOR SUPPRESSORS;

NEUROLOGY;

BMI1 PROTEIN; PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG; BMI1 PROTEIN, HUMAN; BMI1 PROTEIN, MOUSE; CELL SURFACE RECEPTOR; GLI PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; ONCOPROTEIN; PATCHED RECEPTORS; REPRESSOR PROTEIN; SHH PROTEIN, HUMAN; SIGNAL PEPTIDE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

MEDICINE;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BMI1 GENE; BRAIN DEVELOPMENT; CDKN2A GENE; CELL PROLIFERATION; CEREBELLUM; CLINICAL ARTICLE; EMBRYO; GENE; GENE ACTIVATION; GENE LOSS; GENE OVEREXPRESSION; GENE REPRESSION; GRANULE CELL; HEMATOLOGIC DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA; MEDULLOBLASTOMA; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PTCH GENE; STEM CELL; TUMOR SUPPRESSOR GENE; ANIMAL; CELL DIVISION; CYTOLOGY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; PHENOTYPE; PRENATAL DEVELOPMENT; SIGNAL TRANSDUCTION;

ANIMALIA; ERINACEIDAE;

ANIMALS; CELL DIVISION; CEREBELLUM; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEDULLOBLASTOMA; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PHENOTYPE; PROTO-ONCOGENE PROTEINS; RECEPTORS, CELL SURFACE; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEM CELLS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 1642633053     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02385     Document Type: Article

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