-
1
-
-
0022350602
-
Yeast mRNA splicing in vitro.
-
Lin RJ, Newman AJ, Cheng SC, Abelson J. Yeast mRNA splicing in vitro. J Biol Chem 1985, 260:14780-14792.
-
(1985)
J Biol Chem
, vol.260
, pp. 14780-14792
-
-
Lin, R.J.1
Newman, A.J.2
Cheng, S.C.3
Abelson, J.4
-
2
-
-
0024270536
-
RNA processing generates the mature 3′ end of yeast CYC1 messenger RNA in vitro.
-
Butler JS, Platt T. RNA processing generates the mature 3′ end of yeast CYC1 messenger RNA in vitro. Science 1988, 242:1270-1274.
-
(1988)
Science
, vol.242
, pp. 1270-1274
-
-
Butler, J.S.1
Platt, T.2
-
3
-
-
78149301248
-
Coupled RNA polymerase II transcription and 3′ end formation with yeast whole-cell extracts.
-
Mariconti L, Loll B, Schlinkmann K, Wengi A, Meinhart A, Dichtl B. Coupled RNA polymerase II transcription and 3′ end formation with yeast whole-cell extracts. RNA 2010, 16:2205-2217.
-
(2010)
RNA
, vol.16
, pp. 2205-2217
-
-
Mariconti, L.1
Loll, B.2
Schlinkmann, K.3
Wengi, A.4
Meinhart, A.5
Dichtl, B.6
-
4
-
-
0025284904
-
Trans splicing of nematode pre-messenger RNA in vitro.
-
Hannon GJ, Maroney PA, Denker JA, Nilsen TW. Trans splicing of nematode pre-messenger RNA in vitro. Cell 1990, 61:1247- 1255.
-
(1990)
Cell
, vol.61
, pp. 1247-1255
-
-
Hannon, G.J.1
Maroney, P.A.2
Denker, J.A.3
Nilsen, T.W.4
-
5
-
-
0005138411
-
Transcription initiation by RNA polymerase II is inhibited by S-adenosylhomocysteine.
-
Jove R, Manley JL. Transcription initiation by RNA polymerase II is inhibited by S-adenosylhomocysteine. Proc Natl Acad Sci U S A 1982, 79:5842-5846.
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 5842-5846
-
-
Jove, R.1
Manley, J.L.2
-
6
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing.
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Radmark O, Kim S, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003, 425:415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
-
7
-
-
0021223245
-
Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro.
-
Krainer AR, Maniatis T, Ruskin B, Green MR. Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell 1984, 36:993-1005.
-
(1984)
Cell
, vol.36
, pp. 993-1005
-
-
Krainer, A.R.1
Maniatis, T.2
Ruskin, B.3
Green, M.R.4
-
8
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.
-
Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983, 11:1475-1488.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 1475-1488
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
9
-
-
0032648206
-
Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing.
-
Mayeda A, Krainer AR. Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing. Methods Mol Biol 1999, 118:309-314.
-
(1999)
Methods Mol Biol
, vol.118
, pp. 309-314
-
-
Mayeda, A.1
Krainer, A.R.2
-
10
-
-
0025333058
-
Small-scale preparation of extracts from radiolabeled cells efficient in pre-mRNA splicing.
-
Lee KA, Green MR. Small-scale preparation of extracts from radiolabeled cells efficient in pre-mRNA splicing. Methods Enzymol 1990, 181:20-30.
-
(1990)
Methods Enzymol
, vol.181
, pp. 20-30
-
-
Lee, K.A.1
Green, M.R.2
-
11
-
-
0025346111
-
Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells.
-
Krainer AR, Conway GC, Kozak D. Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells. Genes Dev 1990, 4:1158-1171.
-
(1990)
Genes Dev
, vol.4
, pp. 1158-1171
-
-
Krainer, A.R.1
Conway, G.C.2
Kozak, D.3
-
12
-
-
0028831527
-
Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.
-
Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO J 1995, 14:4336-4349.
-
(1995)
EMBO J
, vol.14
, pp. 4336-4349
-
-
Screaton, G.R.1
Cáceres, J.F.2
Mayeda, A.3
Bell, M.V.4
Plebanski, M.5
Jackson, D.G.6
Bell, J.I.7
Krainer, A.R.8
-
13
-
-
0026071593
-
In vitro apolipoprotein B mRNA editing: Identification of a 27S editing complex.
-
Smith HC, Kuo SR, Backus JW, Harris SG, Sparks CE, Sparks JD. In vitro apolipoprotein B mRNA editing: Identification of a 27S editing complex. Proc Natl Acad Sci U S A 1991, 88:1489-1493.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 1489-1493
-
-
Smith, H.C.1
Kuo, S.R.2
Backus, J.W.3
Harris, S.G.4
Sparks, C.E.5
Sparks, J.D.6
-
14
-
-
0025630746
-
Characterization of the apolipoprotein B mRNA editing activity in enterocyte extracts.
-
Driscoll DM, Casanova E. Characterization of the apolipoprotein B mRNA editing activity in enterocyte extracts. J Biol Chem 1990, 265:21401-21403.
-
(1990)
J Biol Chem
, vol.265
, pp. 21401-21403
-
-
Driscoll, D.M.1
Casanova, E.2
-
15
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference.
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001, 409:363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
16
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.
-
Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 2002, 110:563-574.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
18
-
-
0026505629
-
An in vitro system for the editing of ATP synthase subunit 9 mRNA using wheat mitochondrial extracts.
-
Araya A, Domec C, Begu D, Litvak S. An in vitro system for the editing of ATP synthase subunit 9 mRNA using wheat mitochondrial extracts. Proc Natl Acad Sci U S A 1992, 89:1040-1044.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 1040-1044
-
-
Araya, A.1
Domec, C.2
Begu, D.3
Litvak, S.4
-
19
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi.
-
Hammond SM, Boettcher S, Caudy AA, Kobayashi R, Hannon GJ. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 2001, 293:1146-1150.
-
(2001)
Science
, vol.293
, pp. 1146-1150
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
20
-
-
84857761249
-
Pre-mRNA 3′-end processing complex assembly and function.
-
Chan S, Choi E-A, Shi Y. Pre-mRNA 3′-end processing complex assembly and function. WIREs RNA 2011, 2:321-335.
-
(2011)
WIREs RNA
, vol.2
, pp. 321-335
-
-
Chan, S.1
Choi, E.-A.2
Shi, Y.3
-
21
-
-
0025324948
-
A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro.
-
Ge H, Manley JL. A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell 1990, 62:25-34.
-
(1990)
Cell
, vol.62
, pp. 25-34
-
-
Ge, H.1
Manley, J.L.2
-
22
-
-
60349104299
-
The spliceosome: design principles of a dynamic RNP machine.
-
Wahl MC, Will CL, Lührmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009, 136:701-718.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Lührmann, R.3
-
23
-
-
73849107519
-
Regulation of mRNA cap methylation.
-
Cowling VH. Regulation of mRNA cap methylation. Biochem J 2009, 425:295-302.
-
(2009)
Biochem J
, vol.425
, pp. 295-302
-
-
Cowling, V.H.1
-
24
-
-
77951165117
-
Hypermutation induced by APOBEC-1 overexpression can be eliminated.
-
Chen Z, Eggerman TL, Bocharov AV, Baranova IN, Vishnyakova TG, Csako G, Patterson AP. Hypermutation induced by APOBEC-1 overexpression can be eliminated. RNA 2010, 16:1040-1052.
-
(2010)
RNA
, vol.16
, pp. 1040-1052
-
-
Chen, Z.1
Eggerman, T.L.2
Bocharov, A.V.3
Baranova, I.N.4
Vishnyakova, T.G.5
Csako, G.6
Patterson, A.P.7
-
25
-
-
0344012481
-
ADAR2 A-->I editing: site selectivity and editing efficiency are separate events.
-
Källman AM, Sahlin M, Öhman M. ADAR2 A-->I editing: site selectivity and editing efficiency are separate events. Nucleic Acids Res 2003, 31: 4874-4881.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 4874-4881
-
-
Källman, A.M.1
Sahlin, M.2
Öhman, M.3
-
26
-
-
0036847540
-
Ribonuclease activity and RNA binding of recombinant human Dicer.
-
Provost P, Dishart D, Doucet J, Frendewey D, Samuelsson B, Radmark O. Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J 2002, 21:5864-5874.
-
(2002)
EMBO J
, vol.21
, pp. 5864-5874
-
-
Provost, P.1
Dishart, D.2
Doucet, J.3
Frendewey, D.4
Samuelsson, B.5
Radmark, O.6
-
27
-
-
18744407284
-
Purified Argonaute2 and an siRNA form recombinant human RISC.
-
Rivas FV, Tolia NH, Song JJ, Aragon JP, Liu J, Hannon GJ, Joshua-Tor L. Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol 2005, 12:340-349.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 340-349
-
-
Rivas, F.V.1
Tolia, N.H.2
Song, J.J.3
Aragon, J.P.4
Liu, J.5
Hannon, G.J.6
Joshua-Tor, L.7
-
28
-
-
85011940677
-
Role of the snRNAs in spliceosomal active site.
-
Valadkhan S. Role of the snRNAs in spliceosomal active site. RNA Biol 2010, 7:345-353.
-
(2010)
RNA Biol
, vol.7
, pp. 345-353
-
-
Valadkhan, S.1
-
29
-
-
0024408832
-
Identification, purification and characterization of U2 small nuclear ribonucleoprotein auxiliary factor.
-
Zamore PD, Green MR. Identification, purification and characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci U S A 1989, 86:9243-9247.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 9243-9247
-
-
Zamore, P.D.1
Green, M.R.2
-
30
-
-
0017855369
-
Ribonuclease P: an enzyme with an essential RNA component.
-
Stark BC, Kole R, Bowman EJ, Altman S. Ribonuclease P: an enzyme with an essential RNA component. Proc Natl Acad Sci U S A 1978, 75:3717-3721.
-
(1978)
Proc Natl Acad Sci U S A
, vol.75
, pp. 3717-3721
-
-
Stark, B.C.1
Kole, R.2
Bowman, E.J.3
Altman, S.4
-
31
-
-
0021691190
-
The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors.
-
Krämer A, Keller W, Appel B, Lührmann R. The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors. Cell 1984, 38:299-307.
-
(1984)
Cell
, vol.38
, pp. 299-307
-
-
Krämer, A.1
Keller, W.2
Appel, B.3
Lührmann, R.4
-
32
-
-
0023972998
-
Cloning of the RNA8 gene of Saccharomyces cerevisiae, detection of the RNA8 protein, and demonstration that it is essential for nuclear pre-mRNA splicing.
-
Jackson SP, Lossky M, Beggs JD. Cloning of the RNA8 gene of Saccharomyces cerevisiae, detection of the RNA8 protein, and demonstration that it is essential for nuclear pre-mRNA splicing. Mol Cell Biol 1988, 8:1067-1075.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 1067-1075
-
-
Jackson, S.P.1
Lossky, M.2
Beggs, J.D.3
-
33
-
-
0031013878
-
SC35-mediated reconstitution of splicing in U2AF-depleted nuclear extract.
-
MacMillan AM, McCaw PS, Crispino JD, Sharp PA. SC35-mediated reconstitution of splicing in U2AF-depleted nuclear extract. Proc Natl Acad Sci U S A 1997, 94:133-136.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 133-136
-
-
MacMillan, A.M.1
McCaw, P.S.2
Crispino, J.D.3
Sharp, P.A.4
-
34
-
-
78649254115
-
Pervasive and cooperative deadenylation of 3′UTRs by embryonic microRNA families.
-
Wu E, Thivierge C, Flamand M, Mathonnet G, Vashisht AA, Wohlschlegel J, Fabian MR, Sonenberg N, Duchaine TF. Pervasive and cooperative deadenylation of 3′UTRs by embryonic microRNA families. Mol Cell 2010, 40:558-570.
-
(2010)
Mol Cell
, vol.40
, pp. 558-570
-
-
Wu, E.1
Thivierge, C.2
Flamand, M.3
Mathonnet, G.4
Vashisht, A.A.5
Wohlschlegel, J.6
Fabian, M.R.7
Sonenberg, N.8
Duchaine, T.F.9
-
35
-
-
75849145292
-
Expansion of the eukaryotic proteome by alternative splicing.
-
Nilsen TW, Graveley BR. Expansion of the eukaryotic proteome by alternative splicing. Nature 2010, 463:457-463.
-
(2010)
Nature
, vol.463
, pp. 457-463
-
-
Nilsen, T.W.1
Graveley, B.R.2
-
37
-
-
0029001790
-
Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene.
-
Mao X, Schwer B, Shuman S. Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene. Mol Cell Biol 1995, 15: 4167-4174.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4167-4174
-
-
Mao, X.1
Schwer, B.2
Shuman, S.3
-
38
-
-
0029558314
-
Localization and in vitro mutagenesis of the active site in the Saccharomyces cerevisiae mRNA capping enzyme.
-
Shibagaki Y, Gotoh H, Kato M, Mizumoto K. Localization and in vitro mutagenesis of the active site in the Saccharomyces cerevisiae mRNA capping enzyme. J Biochem 1995, 118:1303-1309.
-
(1995)
J Biochem
, vol.118
, pp. 1303-1309
-
-
Shibagaki, Y.1
Gotoh, H.2
Kato, M.3
Mizumoto, K.4
-
39
-
-
0031561370
-
Isolation and characterization of the yeast mRNA capping enzyme β subunit gene encoding RNA 5′-triphosphatase, which is essential for cell viability.
-
Tsukamoto T, Shibagaki Y, Imajoh-Ohmi S, Murakoshi T, Suzuki M, Nakamura A, Gotoh H, Mizumoto K. Isolation and characterization of the yeast mRNA capping enzyme β subunit gene encoding RNA 5′-triphosphatase, which is essential for cell viability. Biochem Biophys Res Commun 1997, 239:116-122.
-
(1997)
Biochem Biophys Res Commun
, vol.239
, pp. 116-122
-
-
Tsukamoto, T.1
Shibagaki, Y.2
Imajoh-Ohmi, S.3
Murakoshi, T.4
Suzuki, M.5
Nakamura, A.6
Gotoh, H.7
Mizumoto, K.8
-
40
-
-
0017161004
-
Modification of the 5′ terminus of mRNA by an RNA (guanine-7-)-methyltransferase from HeLa cells
-
Ensinger MJ, Moss B. Modification of the 5′ terminus of mRNA by an RNA (guanine-7-)-methyltransferase from HeLa cells. J Biol Chem 1976, 251:5283-5291.
-
(1976)
J Biol Chem
, vol.251
, pp. 5283-5291
-
-
Ensinger, M.J.1
Moss, B.2
-
41
-
-
0018531323
-
Transmethylation and transguanylylation in 5′-RNA capping system isolated from rat liver nuclei.
-
Mizumoto K, Lipmann F. Transmethylation and transguanylylation in 5′-RNA capping system isolated from rat liver nuclei. Proc Natl Acad Sci U S A 1979, 76:4961-4965.
-
(1979)
Proc Natl Acad Sci U S A
, vol.76
, pp. 4961-4965
-
-
Mizumoto, K.1
Lipmann, F.2
-
42
-
-
0033522898
-
Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.
-
Saha N, Schwer B, Shuman S. Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes. J Biol Chem 1999, 274:16553-16562.
-
(1999)
J Biol Chem
, vol.274
, pp. 16553-16562
-
-
Saha, N.1
Schwer, B.2
Shuman, S.3
-
43
-
-
2442681755
-
Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II.
-
Mandal SS, Chu C, Wada T, Handa H, Shatkin AJ, Reinberg D. Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II. Proc Natl Acad Sci U S A 2004, 101:7572-7577.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7572-7577
-
-
Mandal, S.S.1
Chu, C.2
Wada, T.3
Handa, H.4
Shatkin, A.J.5
Reinberg, D.6
-
44
-
-
0021747202
-
Recognition of cap structure in splicing in vitro of mRNA precursors.
-
Konarska MM, Padgett RA, Sharp PA. Recognition of cap structure in splicing in vitro of mRNA precursors. Cell 1984, 38:731-736.
-
(1984)
Cell
, vol.38
, pp. 731-736
-
-
Konarska, M.M.1
Padgett, R.A.2
Sharp, P.A.3
-
45
-
-
0023394375
-
Preferential excision of the 5′ proximal intron from mRNA precursors with two introns as mediated by the cap structure.
-
Ohno M, Sakamoto H, Shimura Y. Preferential excision of the 5′ proximal intron from mRNA precursors with two introns as mediated by the cap structure. Proc Natl Acad Sci U S A 1987, 84:5187-5191.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 5187-5191
-
-
Ohno, M.1
Sakamoto, H.2
Shimura, Y.3
-
46
-
-
0029737855
-
A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5′ splice site.
-
Lewis JD, Izaurralde E, Jarmolowski A, McGuigan C, Mattaj IW. A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5′ splice site. Genes Dev 1996, 10:1683-1698.
-
(1996)
Genes Dev
, vol.10
, pp. 1683-1698
-
-
Lewis, J.D.1
Izaurralde, E.2
Jarmolowski, A.3
McGuigan, C.4
Mattaj, I.W.5
-
47
-
-
0030711724
-
Participation of the nuclear cap binding complex in pre-mRNA 3′ processing.
-
Flaherty SM, Fortes P, Izaurralde E, Mattaj IW, Gilmartin GM. Participation of the nuclear cap binding complex in pre-mRNA 3′ processing. Proc Natl Acad Sci U S A 1997, 94:11893-11898.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 11893-11898
-
-
Flaherty, S.M.1
Fortes, P.2
Izaurralde, E.3
Mattaj, I.W.4
Gilmartin, G.M.5
-
48
-
-
0016680603
-
5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation.
-
Muthukrishnan S, Both GW, Furuichi Y, Shatkin AJ. 5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation. Nature 1975, 255:33-37.
-
(1975)
Nature
, vol.255
, pp. 33-37
-
-
Muthukrishnan, S.1
Both, G.W.2
Furuichi, Y.3
Shatkin, A.J.4
-
49
-
-
56849103665
-
The control of mRNA decapping and P-body formation.
-
Franks TM, Lykke-Andersen J. The control of mRNA decapping and P-body formation. Mol Cell 2008, 32:605-615.
-
(2008)
Mol Cell
, vol.32
, pp. 605-615
-
-
Franks, T.M.1
Lykke-Andersen, J.2
-
50
-
-
0037320851
-
Analysis of recombinant yeast decapping enzyme.
-
Steiger M, Carr-Schmid A, Schwartz DC, Kiledjian M, Parker R. Analysis of recombinant yeast decapping enzyme. RNA 2003, 9:231-238.
-
(2003)
RNA
, vol.9
, pp. 231-238
-
-
Steiger, M.1
Carr-Schmid, A.2
Schwartz, D.C.3
Kiledjian, M.4
Parker, R.5
-
51
-
-
0036792078
-
The hDcp2 protein is a mammalian mRNA decapping enzyme.
-
Wang Z, Jiao X, Carr-Schmid A, Kiledjian M. The hDcp2 protein is a mammalian mRNA decapping enzyme. Proc Natl Acad Sci U S A 2002, 99:12663-12668.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12663-12668
-
-
Wang, Z.1
Jiao, X.2
Carr-Schmid, A.3
Kiledjian, M.4
-
52
-
-
1442360375
-
Crystal structure of Dcp1p and its functional implications in mRNA decapping.
-
She M, Decker CJ, Sundramurthy K, Liu Y, Chen N, Parker R, Song H. Crystal structure of Dcp1p and its functional implications in mRNA decapping. Nat Struct Mol Biol 2004, 11:249-256.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 249-256
-
-
She, M.1
Decker, C.J.2
Sundramurthy, K.3
Liu, Y.4
Chen, N.5
Parker, R.6
Song, H.7
-
53
-
-
0037322952
-
The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme.
-
Schwartz D, Decker CJ, Parker R. The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme. RNA 2003, 9:239-251.
-
(2003)
RNA
, vol.9
, pp. 239-251
-
-
Schwartz, D.1
Decker, C.J.2
Parker, R.3
-
54
-
-
0034507456
-
Functions and mechanisms of RNA editing.
-
Gott JM, Emeson RB. Functions and mechanisms of RNA editing. Annu Rev Genet 2000, 34:499-531.
-
(2000)
Annu Rev Genet
, vol.34
, pp. 499-531
-
-
Gott, J.M.1
Emeson, R.B.2
-
55
-
-
0029804892
-
Guide RNA-directed uridine insertion RNA editing in vitro.
-
Byrne EM, Connell GJ, Simpson L. Guide RNA-directed uridine insertion RNA editing in vitro. EMBO J 1996, 15:6758-6765.
-
(1996)
EMBO J
, vol.15
, pp. 6758-6765
-
-
Byrne, E.M.1
Connell, G.J.2
Simpson, L.3
-
56
-
-
0029832215
-
Trypanosome U-deletional RNA editing involves guide RNA-directed endonuclease cleavage, terminal U exonuclease, and RNA ligase activities.
-
Cruz-Reyes J, Sollner-Webb B. Trypanosome U-deletional RNA editing involves guide RNA-directed endonuclease cleavage, terminal U exonuclease, and RNA ligase activities. Proc Natl Acad Sci U S A 1996, 93:8901-8906.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8901-8906
-
-
Cruz-Reyes, J.1
Sollner-Webb, B.2
-
57
-
-
0027942565
-
RNA editing: transfer of genetic information from gRNA to precursor mRNA in vitro.
-
Seiwert SD, Stuart K. RNA editing: transfer of genetic information from gRNA to precursor mRNA in vitro. Science 1994, 266:114-117.
-
(1994)
Science
, vol.266
, pp. 114-117
-
-
Seiwert, S.D.1
Stuart, K.2
-
58
-
-
0029375404
-
Accurate and efficient insertional RNA editing in isolated Physarum mitochondria.
-
Visomirski-Robic LM, Gott JM. Accurate and efficient insertional RNA editing in isolated Physarum mitochondria. RNA 1995, 1:681-691.
-
(1995)
RNA
, vol.1
, pp. 681-691
-
-
Visomirski-Robic, L.M.1
Gott, J.M.2
-
59
-
-
69049120274
-
Distinct roles for sequences upstream of and downstream from Physarum editing sites.
-
Rhee AC, Somerlot BH, Parimi N, Gott JM. Distinct roles for sequences upstream of and downstream from Physarum editing sites. RNA 2009, 15:1753-1765.
-
(2009)
RNA
, vol.15
, pp. 1753-1765
-
-
Rhee, A.C.1
Somerlot, B.H.2
Parimi, N.3
Gott, J.M.4
-
60
-
-
0031694734
-
Analysis of protein complexes assembled on apolipoprotein B mRNA for mooring sequence-dependent RNA editing.
-
Smith HC. Analysis of protein complexes assembled on apolipoprotein B mRNA for mooring sequence-dependent RNA editing. Methods 1998, 15:27-39.
-
(1998)
Methods
, vol.15
, pp. 27-39
-
-
Smith, H.C.1
-
61
-
-
0027200620
-
Molecular cloning of an apolipoprotein B messenger RNA editing protein.
-
Teng B, Burant CF, Davidson NO. Molecular cloning of an apolipoprotein B messenger RNA editing protein. Science 1993, 260:1816-1819.
-
(1993)
Science
, vol.260
, pp. 1816-1819
-
-
Teng, B.1
Burant, C.F.2
Davidson, N.O.3
-
62
-
-
0026441405
-
Three distinct RNA sequence elements are required for efficient apolipoprotein B (apoB) RNA editing in vitro.
-
Backus JW, Smith HC. Three distinct RNA sequence elements are required for efficient apolipoprotein B (apoB) RNA editing in vitro. Nucleic Acids Res 1992, 20:6007-6014.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 6007-6014
-
-
Backus, J.W.1
Smith, H.C.2
-
63
-
-
0033520929
-
Phylogenetic analysis of the apolipoprotein B mRNA-editing region. Evidence for a secondary structure between the mooring sequence and the 3′ efficiency element.
-
Hersberger M, Patarroyo-White S, Arnold KS, Innerarity TL. Phylogenetic analysis of the apolipoprotein B mRNA-editing region. Evidence for a secondary structure between the mooring sequence and the 3′ efficiency element. J Biol Chem 1999, 274:34590-34597.
-
(1999)
J Biol Chem
, vol.274
, pp. 34590-34597
-
-
Hersberger, M.1
Patarroyo-White, S.2
Arnold, K.S.3
Innerarity, T.L.4
-
64
-
-
0033970066
-
Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.
-
Mehta A, Kinter M, Sherman N, Driscoll D. Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA. Mol Cell Biol 2000, 20:1846-1854.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1846-1854
-
-
Mehta, A.1
Kinter, M.2
Sherman, N.3
Driscoll, D.4
-
65
-
-
0036006807
-
C→U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.
-
Mukhopadhyay D, Anant S, Lee RM, Kennedy S, Viskochil D, Davidson NO. C→U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme. Am J Hum Genet 2002, 70:38-50.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 38-50
-
-
Mukhopadhyay, D.1
Anant, S.2
Lee, R.M.3
Kennedy, S.4
Viskochil, D.5
Davidson, N.O.6
-
66
-
-
84857730206
-
Site-selective versus promiscuous A-to-I editing.
-
Wahlstedt H, Öhman M. Site-selective versus promiscuous A-to-I editing. WIREs RNA 2011, 2:761-771.
-
(2011)
WIREs RNA
, vol.2
, pp. 761-771
-
-
Wahlstedt, H.1
Öhman, M.2
-
67
-
-
0030051809
-
A mammalian RNA editing enzyme.
-
Melcher T, Maas S, Herb A, Sprengel R, Seeburg PH, Higuchi M. A mammalian RNA editing enzyme. Nature 1996, 379:460-464.
-
(1996)
Nature
, vol.379
, pp. 460-464
-
-
Melcher, T.1
Maas, S.2
Herb, A.3
Sprengel, R.4
Seeburg, P.H.5
Higuchi, M.6
-
68
-
-
0025943830
-
Substrate specificity of the dsRNA unwinding/modifying activity.
-
Nishikura K, Yoo C, Kim U, Murray JM, Estes PA, Cash FE, Liebhaber SA. Substrate specificity of the dsRNA unwinding/modifying activity. EMBO J 1991, 10:3523-3532.
-
(1991)
EMBO J
, vol.10
, pp. 3523-3532
-
-
Nishikura, K.1
Yoo, C.2
Kim, U.3
Murray, J.M.4
Estes, P.A.5
Cash, F.E.6
Liebhaber, S.A.7
-
69
-
-
0344035669
-
The importance of internal loops within RNA substrates of ADAR1.
-
Lehmann KA, Bass BL. The importance of internal loops within RNA substrates of ADAR1. J Mol Biol 1999, 291:1-13.
-
(1999)
J Mol Biol
, vol.291
, pp. 1-13
-
-
Lehmann, K.A.1
Bass, B.L.2
-
70
-
-
0035542769
-
RNAi is antagonized by A-->I hyper-editing.
-
Scadden AD, Smith CW. RNAi is antagonized by A-->I hyper-editing. EMBO Rep 2001, 2: 1107-1111.
-
(2001)
EMBO Rep
, vol.2
, pp. 1107-1111
-
-
Scadden, A.D.1
Smith, C.W.2
-
71
-
-
0021235185
-
Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors.
-
Padgett RA, Konarska MM, Grabowski PJ, Hardy SF, Sharp PA. Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors. Science 1984, 225:898-903.
-
(1984)
Science
, vol.225
, pp. 898-903
-
-
Padgett, R.A.1
Konarska, M.M.2
Grabowski, P.J.3
Hardy, S.F.4
Sharp, P.A.5
-
72
-
-
0021026456
-
Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts.
-
Hernandez N, Keller W. Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts. Cell 1983, 35:89-99.
-
(1983)
Cell
, vol.35
, pp. 89-99
-
-
Hernandez, N.1
Keller, W.2
-
73
-
-
0032623342
-
Mammalian in vitro splicing assays.
-
Mayeda A, Krainer AR. Mammalian in vitro splicing assays. Methods Mol Biol 1999, 118:315-321.
-
(1999)
Methods Mol Biol
, vol.118
, pp. 315-321
-
-
Mayeda, A.1
Krainer, A.R.2
-
74
-
-
0021719524
-
Excission of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro.
-
Ruskin B, Krainer AR, Maniatis T, Green MR. Excission of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Cell 1984, 38:317-331.
-
(1984)
Cell
, vol.38
, pp. 317-331
-
-
Ruskin, B.1
Krainer, A.R.2
Maniatis, T.3
Green, M.R.4
-
75
-
-
0022135603
-
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro.
-
Krainer AR, Maniatis T. Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell 1985, 42:725-736.
-
(1985)
Cell
, vol.42
, pp. 725-736
-
-
Krainer, A.R.1
Maniatis, T.2
-
76
-
-
0022133074
-
U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing.
-
Black DL, Chabot B, Steitz JA. U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing. Cell 1985, 42:737-750.
-
(1985)
Cell
, vol.42
, pp. 737-750
-
-
Black, D.L.1
Chabot, B.2
Steitz, J.A.3
-
77
-
-
39149083341
-
Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65).
-
Hastings ML, Allemand E, Duelli DM, Myers MP, Krainer AR. Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65). PLoS One 2007, 2:e538.
-
(2007)
PLoS One
, vol.2
-
-
Hastings, M.L.1
Allemand, E.2
Duelli, D.M.3
Myers, M.P.4
Krainer, A.R.5
-
78
-
-
0029863992
-
A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vivo.
-
Tarn WY, Steitz JA. A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vivo. Cell 1996, 84:801-811.
-
(1996)
Cell
, vol.84
, pp. 801-811
-
-
Tarn, W.Y.1
Steitz, J.A.2
-
79
-
-
0029763477
-
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns.
-
Tarn WY, Steitz JA. Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns. Science 1996, 273:1824-1832.
-
(1996)
Science
, vol.273
, pp. 1824-1832
-
-
Tarn, W.Y.1
Steitz, J.A.2
-
80
-
-
0033119176
-
Initial recognition of U12-dependent introns requires both U11/5′ splice-site and U12/branchpoint interactions.
-
Frilander MJ, Steitz JA. Initial recognition of U12-dependent introns requires both U11/5′ splice-site and U12/branchpoint interactions. Genes Dev 1999, 13:851-863.
-
(1999)
Genes Dev
, vol.13
, pp. 851-863
-
-
Frilander, M.J.1
Steitz, J.A.2
-
81
-
-
24044457307
-
A mutational analysis of U12-dependent splice site dinucleotides.
-
Dietrich RC, Fuller JD, Padgett RA. A mutational analysis of U12-dependent splice site dinucleotides. RNA 2005, 11:1430-1440.
-
(2005)
RNA
, vol.11
, pp. 1430-1440
-
-
Dietrich, R.C.1
Fuller, J.D.2
Padgett, R.A.3
-
82
-
-
77949559979
-
A mechanism for splicing control: U11 snRNP as an activator of alternative splicing.
-
Verbeeren J, Niemelä EH, Turunen JJ, Will CL, Ravantti JJ, Lührmann R, Frilander MJ. A mechanism for splicing control: U11 snRNP as an activator of alternative splicing. Mol Cell 2010, 37:821-833.
-
(2010)
Mol Cell
, vol.37
, pp. 821-833
-
-
Verbeeren, J.1
Niemelä, E.H.2
Turunen, J.J.3
Will, C.L.4
Ravantti, J.J.5
Lührmann, R.6
Frilander, M.J.7
-
83
-
-
0026748223
-
Activation of c-src neuron-specific splicing by and unusual RNA element in vivo and in vitro.
-
Black DL. Activation of c-src neuron-specific splicing by and unusual RNA element in vivo and in vitro. Cell 1992, 69:795-807.
-
(1992)
Cell
, vol.69
, pp. 795-807
-
-
Black, D.L.1
-
84
-
-
23844471326
-
HnRNP L represses exon splicing via a regulated exonic splicing silencer.
-
Rothrock CR, House AE, Lynch KW. HnRNP L represses exon splicing via a regulated exonic splicing silencer. EMBO J 2005, 24:2792-2802.
-
(2005)
EMBO J
, vol.24
, pp. 2792-2802
-
-
Rothrock, C.R.1
House, A.E.2
Lynch, K.W.3
-
85
-
-
0025354006
-
Regulated splicing of the Drosophila P transposable element third intron in vitro: somatic repression.
-
Siebel CW, Rio DC. Regulated splicing of the Drosophila P transposable element third intron in vitro: somatic repression. Science 1990, 248: 1200-1208.
-
(1990)
Science
, vol.248
, pp. 1200-1208
-
-
Siebel, C.W.1
Rio, D.C.2
-
86
-
-
0033019048
-
Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences.
-
Schaal TD, Maniatis T. Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences. Mol Cell Biol 1999, 19:1705-1719.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1705-1719
-
-
Schaal, T.D.1
Maniatis, T.2
-
87
-
-
0033998436
-
Characterization of human RNA splice signals by iterative functional selection of splice sites.
-
Lund M, Tange TO, Dyhr-Mikkelsen H, Hansen J, Kjems J. Characterization of human RNA splice signals by iterative functional selection of splice sites. RNA 2000, 6:528-544.
-
(2000)
RNA
, vol.6
, pp. 528-544
-
-
Lund, M.1
Tange, T.O.2
Dyhr-Mikkelsen, H.3
Hansen, J.4
Kjems, J.5
-
88
-
-
0032128255
-
Identification of functional exonic splicing enhancer motifs by individual SR proteins.
-
Liu HX, Zhang M, Krainer AR. Identification of functional exonic splicing enhancer motifs by individual SR proteins. Genes Dev 1998, 12:1998-2012.
-
(1998)
Genes Dev
, vol.12
, pp. 1998-2012
-
-
Liu, H.X.1
Zhang, M.2
Krainer, A.R.3
-
89
-
-
0036207384
-
Listening to silence and understanding nonsense: exonic mutations that affect splicing.
-
Cartegni L, Chew SL, Krainer AR. Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat Rev Genet 2002, 3:285-298.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 285-298
-
-
Cartegni, L.1
Chew, S.L.2
Krainer, A.R.3
-
90
-
-
17844367842
-
Determinants of the inherent strength of human 5′ splice sites.
-
Roca X, Sachidanandam R, Krainer AR. Determinants of the inherent strength of human 5′ splice sites. RNA 2005, 11:683-698.
-
(2005)
RNA
, vol.11
, pp. 683-698
-
-
Roca, X.1
Sachidanandam, R.2
Krainer, A.R.3
-
91
-
-
0033762534
-
Selection of alternative 5′ splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1.
-
Eperon IC, Makarova OV, Mayeda A, Munroe SH, Cáceres JF, Hayward DG, Krainer AR. Selection of alternative 5′ splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1. Mol Cell Biol 2000, 20:8303-8318.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8303-8318
-
-
Eperon, I.C.1
Makarova, O.V.2
Mayeda, A.3
Munroe, S.H.4
Cáceres, J.F.5
Hayward, D.G.6
Krainer, A.R.7
-
92
-
-
57649231776
-
Dynamic regulation of alternative splicing by silencers that modulate 5′ splice site competition.
-
Yu Y, Maroney PA, Denker JA, Zhang XH, Dybkov O, Lührmann R, Jankowsky E, Chasin LA, Nilsen TW. Dynamic regulation of alternative splicing by silencers that modulate 5′ splice site competition. Cell 2008, 135:1224-1236.
-
(2008)
Cell
, vol.135
, pp. 1224-1236
-
-
Yu, Y.1
Maroney, P.A.2
Denker, J.A.3
Zhang, X.H.4
Dybkov, O.5
Lührmann, R.6
Jankowsky, E.7
Chasin, L.A.8
Nilsen, T.W.9
-
93
-
-
59449100357
-
Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex.
-
Kotlajich MV, Crabb TL, Hertel KJ. Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex. Mol Cell Biol 2009, 29:1072-1082.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1072-1082
-
-
Kotlajich, M.V.1
Crabb, T.L.2
Hertel, K.J.3
-
94
-
-
41549168514
-
Antisense masking of an hnRNP A1/A2 intronic splicing silencer corrects SMN2 splicing in transgenic mice.
-
Hua Y, Vickers TA, Okunola HL, Bennett CF, Krainer AR. Antisense masking of an hnRNP A1/A2 intronic splicing silencer corrects SMN2 splicing in transgenic mice. Am J Hum Genet 2008, 82:834-848.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 834-848
-
-
Hua, Y.1
Vickers, T.A.2
Okunola, H.L.3
Bennett, C.F.4
Krainer, A.R.5
-
95
-
-
79952220808
-
Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A.
-
Corrionero A, Miñana B, Valcárcel J. Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A. Genes Dev 2011, 25:445-459.
-
(2011)
Genes Dev
, vol.25
, pp. 445-459
-
-
Corrionero, A.1
Miñana, B.2
Valcárcel, J.3
-
96
-
-
0022549635
-
Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs.
-
Konarska MM, Sharp PA. Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs. Cell 1986, 46:845-855.
-
(1986)
Cell
, vol.46
, pp. 845-855
-
-
Konarska, M.M.1
Sharp, P.A.2
-
97
-
-
0032708815
-
Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels.
-
Das R, Reed R. Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels. RNA 1999, 5:1504-1508.
-
(1999)
RNA
, vol.5
, pp. 1504-1508
-
-
Das, R.1
Reed, R.2
-
98
-
-
0022413541
-
Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences.
-
Frendewey D, Keller W. Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences. Cell 1985, 42:355-367.
-
(1985)
Cell
, vol.42
, pp. 355-367
-
-
Frendewey, D.1
Keller, W.2
-
99
-
-
0024290434
-
Purification and visualization of native spliceosomes.
-
Reed R, Griffith J, Maniatis T. Purification and visualization of native spliceosomes. Cell 1988, 53:949-961.
-
(1988)
Cell
, vol.53
, pp. 949-961
-
-
Reed, R.1
Griffith, J.2
Maniatis, T.3
-
100
-
-
78649650270
-
3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core.
-
Golas MM, Sander B, Bessonov S, Grote M, Wolf E, Kastner B, Stark H, Lührmann R. 3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core. Mol Cell 2010, 40:927-938.
-
(2010)
Mol Cell
, vol.40
, pp. 927-938
-
-
Golas, M.M.1
Sander, B.2
Bessonov, S.3
Grote, M.4
Wolf, E.5
Kastner, B.6
Stark, H.7
Lührmann, R.8
-
101
-
-
0036242097
-
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
-
Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 2002, 8:426-439.
-
(2002)
RNA
, vol.8
, pp. 426-439
-
-
Jurica, M.S.1
Licklider, L.J.2
Gygi, S.R.3
Grigorieff, N.4
Moore, M.J.5
-
102
-
-
37849032986
-
Functional coupling of last-intron splicing and 30-end processing to transcription in vitro: the poly(A) signal couples to splicing before committing to cleavage.
-
Rigo F, Martinson HG. Functional coupling of last-intron splicing and 30-end processing to transcription in vitro: the poly(A) signal couples to splicing before committing to cleavage. Mol Cell Biol 2008, 28:849-862.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 849-862
-
-
Rigo, F.1
Martinson, H.G.2
-
103
-
-
0033834946
-
Coupled in vitro synthesis and splicing of RNA polymerase II transcripts.
-
Ghosh S, Garcia-Blanco MA. Coupled in vitro synthesis and splicing of RNA polymerase II transcripts. RNA 2000, 6:1325-1334.
-
(2000)
RNA
, vol.6
, pp. 1325-1334
-
-
Ghosh, S.1
Garcia-Blanco, M.A.2
-
104
-
-
33745220323
-
Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns.
-
Hicks MJ, Yang CR, Kotlajich MV, Hertel KJ. Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns. PLoS Biol 2006, 4:e147.
-
(2006)
PLoS Biol
, vol.4
-
-
Hicks, M.J.1
Yang, C.R.2
Kotlajich, M.V.3
Hertel, K.J.4
-
105
-
-
78649813424
-
A model in vitro system for co-transcriptional splicing.
-
Yu Y, Das R, Folco EG, Reed R. A model in vitro system for co-transcriptional splicing. Nucleic Acids Res 2010, 38:7570-7578.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 7570-7578
-
-
Yu, Y.1
Das, R.2
Folco, E.G.3
Reed, R.4
-
106
-
-
0036948420
-
Allosteric cascade of spliceosome activation.
-
Brow DA. Allosteric cascade of spliceosome activation. Annu Rev Genet 2002, 36:333-3360.
-
(2002)
Annu Rev Genet
, vol.36
, pp. 333-3360
-
-
Brow, D.A.1
-
107
-
-
0022343426
-
Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing.
-
Rymond BC, Rosbash M. Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing. Nature 1985, 317:735-737.
-
(1985)
Nature
, vol.317
, pp. 735-737
-
-
Rymond, B.C.1
Rosbash, M.2
-
108
-
-
0034649666
-
Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.
-
Yean SL, Wuenschell G, Termini J, Lin RJ. Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. Nature 2000, 408:881-884.
-
(2000)
Nature
, vol.408
, pp. 881-884
-
-
Yean, S.L.1
Wuenschell, G.2
Termini, J.3
Lin, R.J.4
-
109
-
-
0032537739
-
RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2.
-
Raghunathan PL, Guthrie C. RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr Biol 1998, 8:847-855.
-
(1998)
Curr Biol
, vol.8
, pp. 847-855
-
-
Raghunathan, P.L.1
Guthrie, C.2
-
110
-
-
0027153257
-
A U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae.
-
Horowitz DS, Abelson J. A U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae. Mol Cell Biol 1993, 13:2959-2970.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 2959-2970
-
-
Horowitz, D.S.1
Abelson, J.2
-
111
-
-
77955488349
-
The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5′ splice site cleavage during pre-mRNA splicing.
-
Koodathingal P, Novak T, Piccirilli JA, Staley JP. The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5′ splice site cleavage during pre-mRNA splicing. Mol Cell 2010, 39:385-395.
-
(2010)
Mol Cell
, vol.39
, pp. 385-395
-
-
Koodathingal, P.1
Novak, T.2
Piccirilli, J.A.3
Staley, J.P.4
-
112
-
-
46449086933
-
Both catalytic steps of nuclear pre-mRNA splicing are reversible.
-
Tseng CK, Cheng SC. Both catalytic steps of nuclear pre-mRNA splicing are reversible. Science 2008, 320:1782-1784.
-
(2008)
Science
, vol.320
, pp. 1782-1784
-
-
Tseng, C.K.1
Cheng, S.C.2
-
113
-
-
0026654005
-
Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro.
-
Fabrizio P, Abelson J. Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro. Nucleic Acids Res 1992, 20:3659-3664.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 3659-3664
-
-
Fabrizio, P.1
Abelson, J.2
-
114
-
-
33745755054
-
Proximity of conserved U6 and U2 snRNA elements to the 5′ splice site region in activated spliceosomes.
-
Rhode BM, Hartmuth K, Westhof E, Lührmann R. Proximity of conserved U6 and U2 snRNA elements to the 5′ splice site region in activated spliceosomes. EMBO J 2006, 25:2475-2486.
-
(2006)
EMBO J
, vol.25
, pp. 2475-2486
-
-
Rhode, B.M.1
Hartmuth, K.2
Westhof, E.3
Lührmann, R.4
-
115
-
-
67749098066
-
Protein-free small nuclear RNAs catalyze a two-step splicing reaction.
-
Valadkhan S, Mohammadi A, Jaladat Y, Geisler S. Protein-free small nuclear RNAs catalyze a two-step splicing reaction. Proc Natl Acad Sci U S A 2009, 106:11901-11906.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 11901-11906
-
-
Valadkhan, S.1
Mohammadi, A.2
Jaladat, Y.3
Geisler, S.4
-
116
-
-
33344460290
-
Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome.
-
Turner IA, Norman CM, Churcher MJ, Newman AJ. Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome. RNA 2006, 12:375-386.
-
(2006)
RNA
, vol.12
, pp. 375-386
-
-
Turner, I.A.1
Norman, C.M.2
Churcher, M.J.3
Newman, A.J.4
-
117
-
-
0034637161
-
The structural basis of ribosome activity in peptide bond synthesis.
-
Nissen P, Hansen J, Ban N, Moore P, Steitz T. The structural basis of ribosome activity in peptide bond synthesis. Science 2000, 289:920-930.
-
(2000)
Science
, vol.289
, pp. 920-930
-
-
Nissen, P.1
Hansen, J.2
Ban, N.3
Moore, P.4
Steitz, T.5
-
118
-
-
77950516144
-
Conformational dynamics of single pre-mRNA molecules during in vitro splicing.
-
Abelson J, Blanco M, Ditzler MA, Fuller F, Aravamudhan P, Wood M, Villa T, Ryan DE, Pleiss JA, Maeder C, et al. Conformational dynamics of single pre-mRNA molecules during in vitro splicing. Nat Struct Mol Biol 2010, 17:504-512.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 504-512
-
-
Abelson, J.1
Blanco, M.2
Ditzler, M.A.3
Fuller, F.4
Aravamudhan, P.5
Wood, M.6
Villa, T.7
Ryan, D.E.8
Pleiss, J.A.9
Maeder, C.10
-
119
-
-
77954957530
-
Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses.
-
Cherny D, Gooding C, Eperon GE, Coelho MB, Bagshaw CR, Smith CW, Eperon IC. Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses. EMBO J 2010, 29:2161-2172.
-
(2010)
EMBO J
, vol.29
, pp. 2161-2172
-
-
Cherny, D.1
Gooding, C.2
Eperon, G.E.3
Coelho, M.B.4
Bagshaw, C.R.5
Smith, C.W.6
Eperon, I.C.7
-
120
-
-
79952504644
-
Ordered and dynamic assembly of single spliceosomes.
-
Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Ordered and dynamic assembly of single spliceosomes. Science 2011, 331:1289-1295.
-
(2011)
Science
, vol.331
, pp. 1289-1295
-
-
Hoskins, A.A.1
Friedman, L.J.2
Gallagher, S.S.3
Crawford, D.J.4
Anderson, E.G.5
Wombacher, R.6
Ramirez, N.7
Cornish, V.W.8
Gelles, J.9
Moore, M.J.10
-
121
-
-
70350778445
-
Single-molecule analysis of protein-free U2-U6 snRNAs.
-
Guo Z, Karunatilaka KS, Rueda D. Single-molecule analysis of protein-free U2-U6 snRNAs. Nat Struct Mol Biol 2009, 16:1154-1159.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1154-1159
-
-
Guo, Z.1
Karunatilaka, K.S.2
Rueda, D.3
-
123
-
-
77955903010
-
Polycistronic pre-mRNA processing in vitro: snRNP and pre-mRNA role reversal in trans-splicing.
-
Lasda EL, Allen MA, Blumenthal T. Polycistronic pre-mRNA processing in vitro: snRNP and pre-mRNA role reversal in trans-splicing. Genes Dev 2010, 24:1645- 1658.
-
(2010)
Genes Dev
, vol.24
, pp. 1645-1658
-
-
Lasda, E.L.1
Allen, M.A.2
Blumenthal, T.3
-
124
-
-
77954118235
-
Establishment of an in vitro trans-splicing system in Trypanosoma brucei that requires endogenous spliced leader RNA
-
Shaked H, Wachtel C, Tulinski P, Yahia NH, Barda O, Darzynkiewicz E, Nilsen TW, Michaeli S. Establishment of an in vitro trans-splicing system in Trypanosoma brucei that requires endogenous spliced leader RNA. Nucleic Acids Res 2010, 38:e114.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Shaked, H.1
Wachtel, C.2
Tulinski, P.3
Yahia, N.H.4
Barda, O.5
Darzynkiewicz, E.6
Nilsen, T.W.7
Michaeli, S.8
-
125
-
-
0029006578
-
A two-step mechanism for 5′ and 3′ splice-site pairing.
-
Chiara MD, Reed R. A two-step mechanism for 5′ and 3′ splice-site pairing. Nature 1995, 375:510-513.
-
(1995)
Nature
, vol.375
, pp. 510-513
-
-
Chiara, M.D.1
Reed, R.2
-
126
-
-
0030802754
-
Bimolecular exon ligation by the human spliceosome.
-
Anderson K, Moore MJ. Bimolecular exon ligation by the human spliceosome. Science 1997, 276:1712-1716.
-
(1997)
Science
, vol.276
, pp. 1712-1716
-
-
Anderson, K.1
Moore, M.J.2
-
127
-
-
0016194957
-
Poly adenylic acid synthesis in vitro in isolated HeLa cell nuclei and whole cell homogenates.
-
Jelinek WR. Poly adenylic acid synthesis in vitro in isolated HeLa cell nuclei and whole cell homogenates. Cell 1974, 2:197-204.
-
(1974)
Cell
, vol.2
, pp. 197-204
-
-
Jelinek, W.R.1
-
128
-
-
0033039863
-
Specific transcriptional pausing activates polyadenylation in a coupled in vitro system.
-
Yonaha M, Proudfoot NJ. Specific transcriptional pausing activates polyadenylation in a coupled in vitro system. Mol Cell 1999, 3:593-600.
-
(1999)
Mol Cell
, vol.3
, pp. 593-600
-
-
Yonaha, M.1
Proudfoot, N.J.2
-
129
-
-
0018231094
-
Polyadenylation of RNA in a cell-free system from mouse myeloma cells.
-
Cooper DL, Marzluff WF. Polyadenylation of RNA in a cell-free system from mouse myeloma cells. J Biol Chem 1978, 253:8375-8380.
-
(1978)
J Biol Chem
, vol.253
, pp. 8375-8380
-
-
Cooper, D.L.1
Marzluff, W.F.2
-
130
-
-
0022098633
-
Accurate cleavage and polyadenylation of exogenous RNA substrate.
-
Moore CL, Sharp PA. Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell 1985, 41:845-855.
-
(1985)
Cell
, vol.41
, pp. 845-855
-
-
Moore, C.L.1
Sharp, P.A.2
-
131
-
-
0022751114
-
The AAUAAA sequence is required for both cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro.
-
Zarkower D, Stephenson P, Sheets M, Wickens M. The AAUAAA sequence is required for both cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro. Mol Cell Biol 1986, 6:2317-2323.
-
(1986)
Mol Cell Biol
, vol.6
, pp. 2317-2323
-
-
Zarkower, D.1
Stephenson, P.2
Sheets, M.3
Wickens, M.4
-
132
-
-
0020774204
-
Accurate and specific polyadenylation of mRNA precursors in a soluble whole-cell lysate.
-
Manley JL. Accurate and specific polyadenylation of mRNA precursors in a soluble whole-cell lysate. Cell 1983, 33:595-605.
-
(1983)
Cell
, vol.33
, pp. 595-605
-
-
Manley, J.L.1
-
133
-
-
0022018877
-
RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro.
-
Manley JL, Yu H, Ryner L. RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro. Mol Cell Biol 1985, 5:373-379.
-
(1985)
Mol Cell Biol
, vol.5
, pp. 373-379
-
-
Manley, J.L.1
Yu, H.2
Ryner, L.3
-
134
-
-
0024602509
-
Sequences downstream of AAUAAA signals affect pre-mRNA cleavage and polyadenylation in vitro both directly and indirectly.
-
Ryner LC, Takagaki Y, Manley JL. Sequences downstream of AAUAAA signals affect pre-mRNA cleavage and polyadenylation in vitro both directly and indirectly. Mol Cell Biol 1989, 9:1759-1771.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1759-1771
-
-
Ryner, L.C.1
Takagaki, Y.2
Manley, J.L.3
-
135
-
-
0022332463
-
Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences.
-
Hart RP, McDevitt MA, Nevins JR. Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences. Cell 1985, 43:677-683.
-
(1985)
Cell
, vol.43
, pp. 677-683
-
-
Hart, R.P.1
McDevitt, M.A.2
Nevins, J.R.3
-
136
-
-
0029742241
-
RNA structure is a critical determinant of poly(A) site recognition by cleavage and polyadenylation specificity factor.
-
Graveley BR, Fleming ES, Gilmartin GM. RNA structure is a critical determinant of poly(A) site recognition by cleavage and polyadenylation specificity factor. Mol Cell Biol 1996, 16:4942-4951.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4942-4951
-
-
Graveley, B.R.1
Fleming, E.S.2
Gilmartin, G.M.3
-
137
-
-
22344439263
-
Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition.
-
Venkataraman K, Brown KM, Gilmartin GM. Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition. Genes Dev 2005, 19:1315-1327.
-
(2005)
Genes Dev
, vol.19
, pp. 1315-1327
-
-
Venkataraman, K.1
Brown, K.M.2
Gilmartin, G.M.3
-
138
-
-
0023409733
-
Electrophoretic separation of polyadenylation-specific complexes.
-
Skolnik-David H, Moore CL, Sharp PA. Electrophoretic separation of polyadenylation-specific complexes. Genes Dev 1987, 1:672-682.
-
(1987)
Genes Dev
, vol.1
, pp. 672-682
-
-
Skolnik-David, H.1
Moore, C.L.2
Sharp, P.A.3
-
139
-
-
0024762583
-
Four factors are required for 3′-end cleavage of pre-mRNAs.
-
Takagaki Y, Ryner LC, Manley JL. Four factors are required for 3′-end cleavage of pre-mRNAs. Genes Dev 1989, 3:1711-1724.
-
(1989)
Genes Dev
, vol.3
, pp. 1711-1724
-
-
Takagaki, Y.1
Ryner, L.C.2
Manley, J.L.3
-
140
-
-
0025695149
-
A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs.
-
Takagaki Y, Manley JL, MacDonald CC, Wilusz J, Shenk T. A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes Dev 1990, 4:2112-2120.
-
(1990)
Genes Dev
, vol.4
, pp. 2112-2120
-
-
Takagaki, Y.1
Manley, J.L.2
MacDonald, C.C.3
Wilusz, J.4
Shenk, T.5
-
141
-
-
0028025647
-
The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location.
-
MacDonald CC, Wilusz J, Shenk T. The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location. Mol Cell Biol 1994, 14:6647-6654.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6647-6654
-
-
MacDonald, C.C.1
Wilusz, J.2
Shenk, T.3
-
142
-
-
33845902048
-
Polyadenylation factor CPSF-73 is the pre-mRNA 3′-end-processing endonuclease.
-
Mandel CR, Kaneko S, Zhang H, Gebauer D, Vethantham V, Manley JL, Tong L. Polyadenylation factor CPSF-73 is the pre-mRNA 3′-end-processing endonuclease. Nature 2006, 444:953-956.
-
(2006)
Nature
, vol.444
, pp. 953-956
-
-
Mandel, C.R.1
Kaneko, S.2
Zhang, H.3
Gebauer, D.4
Vethantham, V.5
Manley, J.L.6
Tong, L.7
-
143
-
-
0024282810
-
3′ Cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP.
-
Christofori G, Keller W. 3′ Cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP. Cell 1988, 54:875-889.
-
(1988)
Cell
, vol.54
, pp. 875-889
-
-
Christofori, G.1
Keller, W.2
-
144
-
-
0032480229
-
RNA polymerase II is an essential mRNA polyadenylation factor.
-
Hirose Y, Manley JL. RNA polymerase II is an essential mRNA polyadenylation factor. Nature 1998, 395:93-96.
-
(1998)
Nature
, vol.395
, pp. 93-96
-
-
Hirose, Y.1
Manley, J.L.2
-
145
-
-
69249151288
-
Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor.
-
Kühn U, Gündel M, Knoth A, Kerwitz Y, Rüdel S, Wahle E. Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor. J Biol Chem 2009, 284:22803-22814.
-
(2009)
J Biol Chem
, vol.284
, pp. 22803-22814
-
-
Kühn, U.1
Gündel, M.2
Knoth, A.3
Kerwitz, Y.4
Rüdel, S.5
Wahle, E.6
-
146
-
-
70350004235
-
HIV-1 mRNA 3′ end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8.
-
Valente ST, Gilmartin GM, Venkatarama K, Arriagada G, Goff SP. HIV-1 mRNA 3′ end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8. Mol Cell 2009, 36:279-289.
-
(2009)
Mol Cell
, vol.36
, pp. 279-289
-
-
Valente, S.T.1
Gilmartin, G.M.2
Venkatarama, K.3
Arriagada, G.4
Goff, S.P.5
-
147
-
-
33745944934
-
Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3′ end processing and splicing.
-
Kyburz A, Friedlein A, Langen H, Keller W. Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3′ end processing and splicing. Mol Cell 2006, 23:195-205.
-
(2006)
Mol Cell
, vol.23
, pp. 195-205
-
-
Kyburz, A.1
Friedlein, A.2
Langen, H.3
Keller, W.4
-
148
-
-
0031610367
-
U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase.
-
Gunderson SI, Polycarpou-Schwarz M, Mattaj IW. U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1998, 1:255-264.
-
(1998)
Mol Cell
, vol.1
, pp. 255-264
-
-
Gunderson, S.I.1
Polycarpou-Schwarz, M.2
Mattaj, I.W.3
-
149
-
-
34250653243
-
Formation of the 3′ end of histone mRNA: getting closer to the end.
-
Dominski Z, Marzluff WF. Formation of the 3′ end of histone mRNA: getting closer to the end. Gene 2007, 396:373-390.
-
(2007)
Gene
, vol.396
, pp. 373-390
-
-
Dominski, Z.1
Marzluff, W.F.2
-
150
-
-
0022726725
-
Generation of histone mRNA 3′ ends by endonucleolytic cleavage of the pre-mRNA in a snRNP-dependent in vitro reaction.
-
Gick O, Kramer A, Keller W, Birnstiel ML. Generation of histone mRNA 3′ ends by endonucleolytic cleavage of the pre-mRNA in a snRNP-dependent in vitro reaction. EMBO J 1986, 5:1319-1326.
-
(1986)
EMBO J
, vol.5
, pp. 1319-1326
-
-
Gick, O.1
Kramer, A.2
Keller, W.3
Birnstiel, M.L.4
-
151
-
-
0036707527
-
3′ End processing of Drosophila histone pre-mRNAs: requirement for phosphorylated dSLBP and co-evolution of the histone pre-mRNA processing system.
-
Dominski Z, Yang X, Raska CS, Santiago CS, Borchers CH, Duronio RJ, Marzluff WF. 3′ End processing of Drosophila histone pre-mRNAs: requirement for phosphorylated dSLBP and co-evolution of the histone pre-mRNA processing system. Mol Cell Biol 2002, 22:6648-6660.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6648-6660
-
-
Dominski, Z.1
Yang, X.2
Raska, C.S.3
Santiago, C.S.4
Borchers, C.H.5
Duronio, R.J.6
Marzluff, W.F.7
-
152
-
-
26244452759
-
The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing.
-
Dominski Z, Yang XC, Marzluff WF. The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing. Cell 2005, 123:37-48.
-
(2005)
Cell
, vol.123
, pp. 37-48
-
-
Dominski, Z.1
Yang, X.C.2
Marzluff, W.F.3
-
153
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro.
-
Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev 1999, 13:3191-3197.
-
(1999)
Genes Dev
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
154
-
-
0034737298
-
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals.
-
Zamore PD, Tuschl T, Sharp PA, Bartel DP. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 2000, 101:25-33.
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
155
-
-
0036845374
-
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP.
-
Zhang H, Kolb FA, Brondani V, Billy E, Filipowicz W. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J 2002, 21:5875-5885.
-
(2002)
EMBO J
, vol.21
, pp. 5875-5885
-
-
Zhang, H.1
Kolb, F.A.2
Brondani, V.3
Billy, E.4
Filipowicz, W.5
-
156
-
-
34548667878
-
In vitro analysis of microRNA processing using recombinant Dicer and cytoplasmic extracts of HeLa cells.
-
Leuschner PJ, Martinez J. In vitro analysis of microRNA processing using recombinant Dicer and cytoplasmic extracts of HeLa cells. Methods 2007, 43:105-109.
-
(2007)
Methods
, vol.43
, pp. 105-109
-
-
Leuschner, P.J.1
Martinez, J.2
-
157
-
-
0035798415
-
ATP requirements and small interfering RNA structure in the RNA interference pathway.
-
Nykanen A, Haley B, Zamore PD. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 2001, 107:309-321.
-
(2001)
Cell
, vol.107
, pp. 309-321
-
-
Nykanen, A.1
Haley, B.2
Zamore, P.D.3
-
158
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs.
-
Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001, 15:188-200.
-
(2001)
Genes Dev
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
159
-
-
0037009364
-
MicroRNA maturation: stepwise processing and subcellular localization.
-
Lee Y, Jeon K, Lee JT, Kim S, Kim VN. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J 2002, 21:4663-4670.
-
(2002)
EMBO J
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
160
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells.
-
Hammond SM, Bernstein E, Beach D, Hannon GJ. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 2000, 404:293-296.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
161
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate.
-
Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 2001, 20:6877-6888.
-
(2001)
EMBO J
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschl, T.5
-
162
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex.
-
Hutvagner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002, 297:2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
163
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi.
-
Liu J, Carmell MA, Rivas FV, Marsden CG, Thomson JM, Song JJ, Hammond SM, Joshua-Tor L, Hannon GJ. Argonaute2 is the catalytic engine of mammalian RNAi. Science 2004, 305:1437-1441.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
164
-
-
3242736704
-
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
-
Meister G, Landthaler M, Patkaniowska A, Dorsett Y, Teng G, Tuschl T. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell 2004, 15:185-197.
-
(2004)
Mol Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
165
-
-
37648999735
-
A biochemical approach to identifying microRNA targets.
-
Karginov FV, Conaco C, Xuan Z, Schmidt BH, Parker JS, Mandel G, Hannon GJ. A biochemical approach to identifying microRNA targets. Proc Natl Acad Sci U S A 2007, 104:19291-19296.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19291-19296
-
-
Karginov, F.V.1
Conaco, C.2
Xuan, Z.3
Schmidt, B.H.4
Parker, J.S.5
Mandel, G.6
Hannon, G.J.7
-
166
-
-
47749154078
-
Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance.
-
Hendrickson DG, Hogan DJ, Herschlag D, Ferrell JE, Brown PO. Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance. PLoS One 2008, 3:e2126.
-
(2008)
PLoS One
, vol.3
-
-
Hendrickson, D.G.1
Hogan, D.J.2
Herschlag, D.3
Ferrell, J.E.4
Brown, P.O.5
-
167
-
-
34447521718
-
Isolation of microRNA targets by miRNP immunopurification.
-
Easow G, Teleman AA, Cohen SM. Isolation of microRNA targets by miRNP immunopurification. RNA 2007, 13:1198-1204.
-
(2007)
RNA
, vol.13
, pp. 1198-1204
-
-
Easow, G.1
Teleman, A.A.2
Cohen, S.M.3
-
168
-
-
67749132423
-
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
-
Chi SW, Zang JB, Mele A, Darnell RB. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 2009, 460:479-486.
-
(2009)
Nature
, vol.460
, pp. 479-486
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
Darnell, R.B.4
-
169
-
-
80055101895
-
PAR-CliP-a method to identify transcriptome-wide the binding sites of RNA binding proteins.
-
41:pii: 2034. doi:10.3791/2034.
-
Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M, Jungkamp AC, Munschauer M, et al. PAR-CliP-a method to identify transcriptome-wide the binding sites of RNA binding proteins. J Vis Exp 2010, 41:pii: 2034. doi:10.3791/2034.
-
(2010)
J Vis Exp
-
-
Hafner, M.1
Landthaler, M.2
Burger, L.3
Khorshid, M.4
Hausser, J.5
Berninger, P.6
Rothballer, A.7
Ascano, M.8
Jungkamp, A.C.9
Munschauer, M.10
-
170
-
-
1842766252
-
A dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila.
-
Pham JW, Pellino JL, Lee YS, Carthew RW, Sontheimer EJ. A dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 2004, 117:83-94.
-
(2004)
Cell
, vol.117
, pp. 83-94
-
-
Pham, J.W.1
Pellino, J.L.2
Lee, Y.S.3
Carthew, R.W.4
Sontheimer, E.J.5
-
171
-
-
1642603943
-
RISC assembly defects in the Drosophila RNAi mutant armitage.
-
Tomari Y, Du T, Haley B, Schwarz DS, Bennett R, Cook HA, Koppetsch BS, Theurkauf WE, Zamore PD. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 2004, 116:831-841.
-
(2004)
Cell
, vol.116
, pp. 831-841
-
-
Tomari, Y.1
Du, T.2
Haley, B.3
Schwarz, D.S.4
Bennett, R.5
Cook, H.A.6
Koppetsch, B.S.7
Theurkauf, W.E.8
Zamore, P.D.9
-
172
-
-
8844271740
-
A protein sensor for siRNA asymmetry.
-
Tomari Y, Matranga C, Haley B, Martinez N, Zamore PD. A protein sensor for siRNA asymmetry. Science 2004, 306:1377-1380.
-
(2004)
Science
, vol.306
, pp. 1377-1380
-
-
Tomari, Y.1
Matranga, C.2
Haley, B.3
Martinez, N.4
Zamore, P.D.5
-
173
-
-
34547944309
-
MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F.
-
Mathonnet G, Fabian MR, Svitkin YV, Parsyan A, Huck L, Murata T, Biffo S, Merrick WC, Darzynkiewicz E, Pillai RS, et al. MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science 2007, 317:1764-1767.
-
(2007)
Science
, vol.317
, pp. 1764-1767
-
-
Mathonnet, G.1
Fabian, M.R.2
Svitkin, Y.V.3
Parsyan, A.4
Huck, L.5
Murata, T.6
Biffo, S.7
Merrick, W.C.8
Darzynkiewicz, E.9
Pillai, R.S.10
-
174
-
-
70349177026
-
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.
-
Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, et al. Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol Cell 2009, 35:868-880.
-
(2009)
Mol Cell
, vol.35
, pp. 868-880
-
-
Fabian, M.R.1
Mathonnet, G.2
Sundermeier, T.3
Mathys, H.4
Zipprich, J.T.5
Svitkin, Y.V.6
Rivas, F.7
Jinek, M.8
Wohlschlegel, J.9
Doudna, J.A.10
-
175
-
-
80052991624
-
3′ End formation of PIWI-interacting RNAs in vitro.
-
Kawaoka S, Izumi N, Katsuma S, Tomari Y. 3′ End formation of PIWI-interacting RNAs in vitro. Mol Cell 2011, 43:1015-1022.
-
(2011)
Mol Cell
, vol.43
, pp. 1015-1022
-
-
Kawaoka, S.1
Izumi, N.2
Katsuma, S.3
Tomari, Y.4
|