메뉴 건너뛰기




Volumn 6, Issue 4, 2000, Pages 528-544

Characterization of human RNA splice signals by iterative functional selection of splice sites

Author keywords

3' splice site; Branchpoint; In vitro selection; Lariat; Polyadenylation; RNA splicing; SR proteins

Indexed keywords

RNA;

EID: 0033998436     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838200992033     Document Type: Article
Times cited : (12)

References (55)
  • 1
    • 0030911051 scopus 로고    scopus 로고
    • Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
    • Abovich N, Rosbash M. 1997. Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89:403-412.
    • (1997) Cell , vol.89 , pp. 403-412
    • Abovich, N.1    Rosbash, M.2
  • 2
    • 0023700865 scopus 로고
    • Unusual branch point selection involved in the splicing of the alternatively processed Calcitonin/CGRP-I pre-mRNA
    • Adema GJ, Bovenberg RAL, Jansz HS, Baas PD. 1988. Unusual branch point selection involved in the splicing of the alternatively processed Calcitonin/CGRP-I pre-mRNA. Nucleic Acids Res 16:9513-9526.
    • (1988) Nucleic Acids Res , vol.16 , pp. 9513-9526
    • Adema, G.J.1    Bovenberg, R.A.L.2    Jansz, H.S.3    Baas, P.D.4
  • 3
    • 0022974809 scopus 로고
    • Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA
    • Aebi M, Hornig H, Padgett RA, Reiser J, Weissmann C. 1986. Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA. Cell 47:555-565.
    • (1986) Cell , vol.47 , pp. 555-565
    • Aebi, M.1    Hornig, H.2    Padgett, R.A.3    Reiser, J.4    Weissmann, C.5
  • 4
    • 0030802754 scopus 로고    scopus 로고
    • Bimolecular exon ligation by the human spliceosome
    • Anderson K, Moore MJ. 1997. Bimolecular exon ligation by the human spliceosome. Science 276:1712-1716.
    • (1997) Science , vol.276 , pp. 1712-1716
    • Anderson, K.1    Moore, M.J.2
  • 5
    • 0032521186 scopus 로고    scopus 로고
    • A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
    • Berglund JA, Abovich N, Rosbash M. 1998. A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. Genes & Dev 12:858-867.
    • (1998) Genes & Dev , vol.12 , pp. 858-867
    • Berglund, J.A.1    Abovich, N.2    Rosbash, M.3
  • 6
    • 0030696675 scopus 로고    scopus 로고
    • The splicing factor BBP interacts specifically with the pre-mRNA branch-point sequence UACUAAC
    • Berglund JA, Chua K, Abovich N, Reed R, Rosbash M. 1997. The splicing factor BBP interacts specifically with the pre-mRNA branch-point sequence UACUAAC. Cell 89:781-787.
    • (1997) Cell , vol.89 , pp. 781-787
    • Berglund, J.A.1    Chua, K.2    Abovich, N.3    Reed, R.4    Rosbash, M.5
  • 7
    • 0001468848 scopus 로고    scopus 로고
    • Splicing of precursors to mRNA by spliceosomes
    • Gesteland RF, Cech TR, Atkins JF, eds. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
    • Burge CB, Tuschl T, Sharp PA. 1999. Splicing of precursors to mRNA by spliceosomes. In: Gesteland RF, Cech TR, Atkins JF, eds. The RNA world. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, pp 525-560.
    • (1999) The RNA World , pp. 525-560
    • Burge, C.B.1    Tuschl, T.2    Sharp, P.A.3
  • 8
    • 0031299450 scopus 로고    scopus 로고
    • Functional crosstalk between exon enhancers, polypyrimidine tracts and branchpoint sequences
    • Buvoli M, Mayer SA, Patton JG 1997. Functional crosstalk between exon enhancers, polypyrimidine tracts and branchpoint sequences. EMBO J 16:7174-7183.
    • (1997) EMBO J , vol.16 , pp. 7174-7183
    • Buvoli, M.1    Mayer, S.A.2    Patton, J.G.3
  • 9
    • 0024404487 scopus 로고
    • The 216-nucleotide intron of the E1A pre-mRNA contains a hairpin structure that permits utilization of unusually distant branch acceptors
    • Chebli K, Gattoni R, Schmitt P, Hildwein G, Stevenin J. 1989. The 216-nucleotide intron of the E1A pre-mRNA contains a hairpin structure that permits utilization of unusually distant branch acceptors. Mol Cell Biol 9:4852-4861.
    • (1989) Mol Cell Biol , vol.9 , pp. 4852-4861
    • Chebli, K.1    Gattoni, R.2    Schmitt, P.3    Hildwein, G.4    Stevenin, J.5
  • 10
    • 0029894931 scopus 로고    scopus 로고
    • Identification of proteins that interact with exon sequences, splice sites and the branchpoint sequence during each stage of spliceosome assembly
    • Chiara MD, Gozani O, Bennett M, Champion-Arnaud P, Palandjian L, Reed R. 1996. Identification of proteins that interact with exon sequences, splice sites and the branchpoint sequence during each stage of spliceosome assembly. Mol Cell Biol 16:3317-3326.
    • (1996) Mol Cell Biol , vol.16 , pp. 3317-3326
    • Chiara, M.D.1    Gozani, O.2    Bennett, M.3    Champion-Arnaud, P.4    Palandjian, L.5    Reed, R.6
  • 11
    • 0030857005 scopus 로고    scopus 로고
    • Functional analysis of the polypyrimidine tract in pre-mRNA splicing
    • Coolidge CJ, Seely RJ, Patton JG. 1997. Functional analysis of the polypyrimidine tract in pre-mRNA splicing. Nucleic Acids Res 25:888-896.
    • (1997) Nucleic Acids Res , vol.25 , pp. 888-896
    • Coolidge, C.J.1    Seely, R.J.2    Patton, J.G.3
  • 13
    • 0028858388 scopus 로고
    • Inefficient spliceosome assembly and abnormal branch site selection in splicing of an HIV-1 transcript in vitro
    • Dyhr-Mikkelsen H, Kjems J. 1995. Inefficient spliceosome assembly and abnormal branch site selection in splicing of an HIV-1 transcript in vitro. J Biol Chem 270:24060-24066.
    • (1995) J Biol Chem , vol.270 , pp. 24060-24066
    • Dyhr-Mikkelsen, H.1    Kjems, J.2
  • 14
    • 0030611640 scopus 로고    scopus 로고
    • U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
    • Fleckner J, Zhang M, Valcárcel J, Green MR. 1997. U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. Genes & Dev 11:1864-1872.
    • (1997) Genes & Dev , vol.11 , pp. 1864-1872
    • Fleckner, J.1    Zhang, M.2    Valcárcel, J.3    Green, M.R.4
  • 15
    • 0024452160 scopus 로고
    • Alterations in the polypyrimidine sequence affect the in vitro splicing reactions catalyzed by HeLa cell-free preparations
    • Freyer GA, O'Brien JP, Hurwitz J. 1989. Alterations in the polypyrimidine sequence affect the in vitro splicing reactions catalyzed by HeLa cell-free preparations. J Biol Chem 264:14631-14637.
    • (1989) J Biol Chem , vol.264 , pp. 14631-14637
    • Freyer, G.A.1    O'Brien, J.P.2    Hurwitz, J.3
  • 16
    • 0029372979 scopus 로고
    • The superfamily of arginine/serine-rich splicing factors
    • Fu XD. 1995. The superfamily of arginine/serine-rich splicing factors. RNA 1:663-680.
    • (1995) RNA , vol.1 , pp. 663-680
    • Fu, X.D.1
  • 17
    • 0024842159 scopus 로고
    • Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns
    • Garcia-Blanco MA, Jamison SF, Sharp PA. 1989. Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes & Dev 3:1874-1886.
    • (1989) Genes & Dev , vol.3 , pp. 1874-1886
    • Garcia-Blanco, M.A.1    Jamison, S.F.2    Sharp, P.A.3
  • 18
    • 0030044836 scopus 로고    scopus 로고
    • Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A
    • Gozani O, Feld R, Reed R. 1996. Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A. Genes & Dev 10:233-243.
    • (1996) Genes & Dev , vol.10 , pp. 233-243
    • Gozani, O.1    Feld, R.2    Reed, R.3
  • 19
    • 0031878108 scopus 로고    scopus 로고
    • A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site
    • Gozani O, Potashkin J, Reed R. 1998. A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site. Mol Cell Biol 18:4752-4760.
    • (1998) Mol Cell Biol , vol.18 , pp. 4752-4760
    • Gozani, O.1    Potashkin, J.2    Reed, R.3
  • 20
    • 0025787954 scopus 로고
    • Biochemical mechanisms of constitutive and regulated pre-mRNA splicing
    • Green MR. 1991. Biochemical mechanisms of constitutive and regulated pre-mRNA splicing. Annu Rev Cell Biol 7:559-599.
    • (1991) Annu Rev Cell Biol , vol.7 , pp. 559-599
    • Green, M.R.1
  • 21
    • 0025279906 scopus 로고
    • Distribution and consensus of branch point signals in eukaryotic genes: A computerized statistical analysis
    • Harris NL, Senapathy P. 1990. Distribution and consensus of branch point signals in eukaryotic genes: A computerized statistical analysis. Nucleic Acids Res 18:3015-3019.
    • (1990) Nucleic Acids Res , vol.18 , pp. 3015-3019
    • Harris, N.L.1    Senapathy, P.2
  • 22
    • 0023877583 scopus 로고
    • Unusual branch point selection in processing of human growth hormone pre-mRNA
    • Hartmuth K, Barta A. 1988. Unusual branch point selection in processing of human growth hormone pre-mRNA. Mol Cell Biol 8:2011-2020.
    • (1988) Mol Cell Biol , vol.8 , pp. 2011-2020
    • Hartmuth, K.1    Barta, A.2
  • 23
    • 0023037969 scopus 로고
    • Effects of mutations at the lariat branch acceptor site on β-globin pre-mRNA splicing in vitro
    • Hornig H, Aebi M, Weissmann C. 1986. Effects of mutations at the lariat branch acceptor site on β-globin pre-mRNA splicing in vitro. Nature 324:589-591.
    • (1986) Nature , vol.324 , pp. 589-591
    • Hornig, H.1    Aebi, M.2    Weissmann, C.3
  • 24
    • 0026655649 scopus 로고
    • The spliceosome assembly pathway in mammalian extracts
    • Jamison SF, Crow A, Garcia-Blanco MA. 1992. The spliceosome assembly pathway in mammalian extracts. Mol Cell Biol 12:4279-4287.
    • (1992) Mol Cell Biol , vol.12 , pp. 4279-4287
    • Jamison, S.F.1    Crow, A.2    Garcia-Blanco, M.A.3
  • 25
    • 0037829771 scopus 로고
    • Intron splicing: A conserved internal signal in introns of animal pre-mRNAs
    • Keller EB, Noon WA. 1984. Intron splicing: A conserved internal signal in introns of animal pre-mRNAs. Proc Natl Acad Sci USA 81:7417-7420.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 7417-7420
    • Keller, E.B.1    Noon, W.A.2
  • 26
    • 0026668641 scopus 로고
    • Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex
    • Kramer A. 1992. Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex. Mol Cell Biol 12:4545-4552.
    • (1992) Mol Cell Biol , vol.12 , pp. 4545-4552
    • Kramer, A.1
  • 27
    • 0023390960 scopus 로고
    • A mutational analysis of spliceosome assembly: Evidence for splice site collaboration during spliceosome formation
    • Lamond Al, Konarska MM, Sharp PA. 1987. A mutational analysis of spliceosome assembly: Evidence for splice site collaboration during spliceosome formation. Genes & Dev 1:532-543.
    • (1987) Genes & Dev , vol.1 , pp. 532-543
    • Lamond, Al.1    Konarska, M.M.2    Sharp, P.A.3
  • 28
    • 0025040786 scopus 로고
    • Sequence requirements in different steps of the pre-mRNA splicing reaction: Analysis by the RNA modification-exclusion technique
    • Lang KM, Keller W. 1990. Sequence requirements in different steps of the pre-mRNA splicing reaction: Analysis by the RNA modification-exclusion technique. Mol Cell Biol 10:4942-4947.
    • (1990) Mol Cell Biol , vol.10 , pp. 4942-4947
    • Lang, K.M.1    Keller, W.2
  • 29
    • 0032865541 scopus 로고    scopus 로고
    • Genomic-scale quantitative analysis of yeast pre-mRNA splicing: Implications for splice-site recognition
    • Lopez PJ, Séraphin B. 1999. Genomic-scale quantitative analysis of yeast pre-mRNA splicing: Implications for splice-site recognition. RNA 5:1135-1137.
    • (1999) RNA , vol.5 , pp. 1135-1137
    • Lopez, P.J.1    Séraphin, B.2
  • 31
    • 0020050314 scopus 로고
    • A catalogue of splice junction sequences
    • Mount SM. 1982. A catalogue of splice junction sequences. Nucleic Acids Res 10:459-472.
    • (1982) Nucleic Acids Res , vol.10 , pp. 459-472
    • Mount, S.M.1
  • 32
    • 0024747748 scopus 로고
    • Mammalian U2 snRNP has a sequence-specific RNA-binding activity
    • Nelson KK, Green MR. 1989. Mammalian U2 snRNP has a sequence-specific RNA-binding activity. Genes & Dev 3:1562-1571.
    • (1989) Genes & Dev , vol.3 , pp. 1562-1571
    • Nelson, K.K.1    Green, M.R.2
  • 33
    • 1842326159 scopus 로고    scopus 로고
    • The branchpoint residue is recognized during commitment complex formation before being bulged out of the U2 snRNA-pre-mRNA duplex
    • Pascolo E, Séraphin B. 1997. The branchpoint residue is recognized during commitment complex formation before being bulged out of the U2 snRNA-pre-mRNA duplex. Mol Cell Biol 17:3469-3476.
    • (1997) Mol Cell Biol , vol.17 , pp. 3469-3476
    • Pascolo, E.1    Séraphin, B.2
  • 34
    • 0028205987 scopus 로고
    • Branch nucleophile selection in pre-mRNA splicing: Evidence for the bulged duplex model
    • Query CC, Moore MJ, Sharp PA. 1994. Branch nucleophile selection in pre-mRNA splicing: Evidence for the bulged duplex model. Genes & Dev 8:587-597.
    • (1994) Genes & Dev , vol.8 , pp. 587-597
    • Query, C.C.1    Moore, M.J.2    Sharp, P.A.3
  • 35
    • 0029917043 scopus 로고    scopus 로고
    • Three recognition events at the branch-site adenine
    • Query CC, Strobel SA, Sharp PA. 1996. Three recognition events at the branch-site adenine. EMBO J 15:1392-1402.
    • (1996) EMBO J , vol.15 , pp. 1392-1402
    • Query, C.C.1    Strobel, S.A.2    Sharp, P.A.3
  • 36
    • 0024808994 scopus 로고
    • The organization of 3′ splice-site sequences in mammalian introns
    • Reed R. 1989. The organization of 3′ splice-site sequences in mammalian introns. Genes & Dev 3:2113-2123.
    • (1989) Genes & Dev , vol.3 , pp. 2113-2123
    • Reed, R.1
  • 37
    • 0021887989 scopus 로고
    • Intron sequences involved in lariat formation during pre-mRNA splicing
    • Reed R, Maniatis T. 1985. Intron sequences involved in lariat formation during pre-mRNA splicing. Cell 41:95-105.
    • (1985) Cell , vol.41 , pp. 95-105
    • Reed, R.1    Maniatis, T.2
  • 38
    • 0024100723 scopus 로고
    • The role of the mammalian branchpoint sequence in pre-mRNA splicing
    • Reed R, Maniatis T. 1988. The role of the mammalian branchpoint sequence in pre-mRNA splicing. Genes & Dev 2:1268-1276.
    • (1988) Genes & Dev , vol.2 , pp. 1268-1276
    • Reed, R.1    Maniatis, T.2
  • 39
    • 0027233694 scopus 로고
    • A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing
    • Roscigno RF, Weiner M, Garcia-Blanco MA. 1993. A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing. J Biol Chem 268: 11222-11229.
    • (1993) J Biol Chem , vol.268 , pp. 11222-11229
    • Roscigno, R.F.1    Weiner, M.2    Garcia-Blanco, M.A.3
  • 40
    • 0027428138 scopus 로고
    • Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA
    • Ruby SW, Chang TH, Abelson J. 1993. Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA. Genes & Dev 7:1909-1925.
    • (1993) Genes & Dev , vol.7 , pp. 1909-1925
    • Ruby, S.W.1    Chang, T.H.2    Abelson, J.3
  • 41
    • 0022380943 scopus 로고
    • Role of the 3′ splice site consensus sequence in mammalian pre-mRNA splicing
    • Ruskin B, Green MR. 1985. Role of the 3′ splice site consensus sequence in mammalian pre-mRNA splicing. Nature 317:732-734.
    • (1985) Nature , vol.317 , pp. 732-734
    • Ruskin, B.1    Green, M.R.2
  • 42
    • 0025008168 scopus 로고
    • Sequence logos: A new way to display consensus sequences
    • Schneider TD, Stephens RM. 1990. Sequence logos: A new way to display consensus sequences. Nucleic Acids Res 18:6097-6100.
    • (1990) Nucleic Acids Res , vol.18 , pp. 6097-6100
    • Schneider, T.D.1    Stephens, R.M.2
  • 43
    • 0023651307 scopus 로고
    • RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression
    • Shapiro MB, Senapathy P. 1987. RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression. Nucleic Acids Res 15:7155-7174.
    • (1987) Nucleic Acids Res , vol.15 , pp. 7155-7174
    • Shapiro, M.B.1    Senapathy, P.2
  • 44
    • 0029055472 scopus 로고
    • Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
    • Singh R, Valcarcel J, Green MR. 1995. Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins. Science 268:1173-1176.
    • (1995) Science , vol.268 , pp. 1173-1176
    • Singh, R.1    Valcarcel, J.2    Green, M.R.3
  • 45
    • 0027214101 scopus 로고
    • Scanning and competition between AGs are involved in 3′ splice site selection in mammalian introns
    • Smith CW, Chu TT, Nadal-Ginard B. 1993. Scanning and competition between AGs are involved in 3′ splice site selection in mammalian introns. Mol Cell Biol 13:4939-4952.
    • (1993) Mol Cell Biol , vol.13 , pp. 4939-4952
    • Smith, C.W.1    Chu, T.T.2    Nadal-Ginard, B.3
  • 46
    • 0024470631 scopus 로고
    • Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns
    • Smith CW, Porro EB, Patton JG, Nadal-Ginard B. 1989. Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns. Nature 342:243-247.
    • (1989) Nature , vol.342 , pp. 243-247
    • Smith, C.W.1    Porro, E.B.2    Patton, J.G.3    Nadal-Ginard, B.4
  • 47
    • 0028209981 scopus 로고
    • Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly
    • Staknis D, Reed R. 1994. Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly. Mol Cell Biol 14:2994-3005.
    • (1994) Mol Cell Biol , vol.14 , pp. 2994-3005
    • Staknis, D.1    Reed, R.2
  • 48
    • 0032489021 scopus 로고    scopus 로고
    • Mechanical devices of the spliceosome: Motors, clocks, springs, and things
    • Staley JP, Guthrie C. 1998. Mechanical devices of the spliceosome: Motors, clocks, springs, and things. Cell 92:315-326.
    • (1998) Cell , vol.92 , pp. 315-326
    • Staley, J.P.1    Guthrie, C.2
  • 49
    • 0024743838 scopus 로고
    • Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing
    • Wu J, Manley JL 1989. Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing. Genes & Dev 3:1553-1561.
    • (1989) Genes & Dev , vol.3 , pp. 1553-1561
    • Wu, J.1    Manley, J.L.2
  • 50
    • 0030919832 scopus 로고    scopus 로고
    • The herpes simplex virus type 1 2.0-kilobase latency-associated transcript is a stable intron which branches at a guanosine
    • Zabolotny JM, Krummenacher C, Fraser NW. 1997. The herpes simplex virus type 1 2.0-kilobase latency-associated transcript is a stable intron which branches at a guanosine. J Virol 71:4199-4208.
    • (1997) J Virol , vol.71 , pp. 4199-4208
    • Zabolotny, J.M.1    Krummenacher, C.2    Fraser, N.W.3
  • 51
    • 0026716104 scopus 로고
    • SR proteins: A conserved family of pre-mRNA splicing factors
    • Zahler AM, Lane WS, Stolk JA, Roth MB. 1992. SR proteins: A conserved family of pre-mRNA splicing factors. Genes & Dev 6:837-847.
    • (1992) Genes & Dev , vol.6 , pp. 837-847
    • Zahler, A.M.1    Lane, W.S.2    Stolk, J.A.3    Roth, M.B.4
  • 52
    • 0026569967 scopus 로고
    • Cloning and domain structure of the mammalian splicing factor U2AF
    • Zamore PD, Patton JG, Green MR. 1992. Cloning and domain structure of the mammalian splicing factor U2AF. Nature 355:609-614.
    • (1992) Nature , vol.355 , pp. 609-614
    • Zamore, P.D.1    Patton, J.G.2    Green, M.R.3
  • 53
    • 0002862339 scopus 로고
    • UACUAAC is the preferred branch site for mammalian mRNA splicing
    • Zhuang Y, Goldstein AM, Weiner AM. 1989. UACUAAC is the preferred branch site for mammalian mRNA splicing. Proc Natl Acad Sci USA 86:2752-2756.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2752-2756
    • Zhuang, Y.1    Goldstein, A.M.2    Weiner, A.M.3
  • 54
    • 0024744567 scopus 로고
    • A compensatory base change in human U2 snRNA can suppress a branch site mutation
    • Zhuang Y, Weiner AM. 1989. A compensatory base change in human U2 snRNA can suppress a branch site mutation. Genes & Dev 3:1545-1552.
    • (1989) Genes & Dev , vol.3 , pp. 1545-1552
    • Zhuang, Y.1    Weiner, A.M.2
  • 55
    • 0025076272 scopus 로고
    • The conserved dinucleotide AG of the 3′ splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors
    • Zhuang Y, Weiner AM. 1990. The conserved dinucleotide AG of the 3′ splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors. Gene 90:263-269.
    • (1990) Gene , vol.90 , pp. 263-269
    • Zhuang, Y.1    Weiner, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.