-
1
-
-
0042671357
-
Pre-mRNA splicing: Awash in a sea of proteins
-
Jurica, M.S. & Moore, M.J. Pre-mRNA splicing: awash in a sea of proteins. Mol. Cell 12, 5-14 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 5-14
-
-
Jurica, M.S.1
Moore, M.J.2
-
2
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl, M.C., Will, C.L. & Luhrmann, R. The spliceosome: design principles of a dynamic RNP machine. Cell 136, 701-718 (2009).
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
3
-
-
0032489021
-
Mechanical devices of the spliceosome: Motors, clocks, springs, and things
-
Staley, J.P. & Guthrie, C. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92, 315-326 (1998).
-
(1998)
Cell
, vol.92
, pp. 315-326
-
-
Staley, J.P.1
Guthrie, C.2
-
4
-
-
0027287852
-
A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates
-
DOI 10.1016/0092-8674(93)90363-U
-
Burgess, S.M. & Guthrie, C. A mechanism to enhance mRNA splicing fdelity: the RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates. Cell 73, 1377-1391 (1993). (Pubitemid 23201150)
-
(1993)
Cell
, vol.73
, Issue.7
, pp. 1377-1391
-
-
Burgess, S.M.1
Guthrie, C.2
-
5
-
-
0023370562
-
A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation
-
Couto, J.R., Tamm, J., Parker, R. & Guthrie, C. A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation. Genes Dev. 1, 445-455 (1987).
-
(1987)
Genes Dev.
, vol.1
, pp. 445-455
-
-
Couto, J.R.1
Tamm, J.2
Parker, R.3
Guthrie, C.4
-
6
-
-
33744937919
-
Exon ligation is proofread by the DExD/H-box ATPase Prp22p
-
Mayas, R.M., Maita, H. & Staley, J.P. Exon ligation is proofread by the DExD/H-box ATPase Prp22p. Nat. Struct. Mol. Biol. 13, 482-490 (2006).
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 482-490
-
-
Mayas, R.M.1
Maita, H.2
Staley, J.P.3
-
7
-
-
36749080450
-
Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fdelity of spliceosome assembly
-
Xu, Y.Z. & Query, C.C. Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fdelity of spliceosome assembly. Mol. Cell 28, 838-849 (2007).
-
(2007)
Mol. Cell
, vol.28
, pp. 838-849
-
-
Xu, Y.Z.1
Query, C.C.2
-
8
-
-
44449097780
-
Do-it-yourself guide: How to use the modern single-molecule toolkit
-
Walter, N.G., Huang, C.Y., Manzo, A.J. & Sobhy, M.A. Do-it-yourself guide: how to use the modern single-molecule toolkit. Nat. Methods 5, 475-489 (2008).
-
(2008)
Nat. Methods
, vol.5
, pp. 475-489
-
-
Walter, N.G.1
Huang, C.Y.2
Manzo, A.J.3
Sobhy, M.A.4
-
9
-
-
0029012941
-
Purifcation of the spliceosome A-complex and its visualization by electron microscopy
-
Furman, E. & Glitz, D.G. Purifcation of the spliceosome A-complex and its visualization by electron microscopy. J. Biol. Chem. 270, 15515-15522 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15515-15522
-
-
Furman, E.1
Glitz, D.G.2
-
10
-
-
0036242097
-
And characterization of native spliceosomes suitable for three-dimensional structural analysis
-
Jurica, M.S., Licklider, L.J., Gygi, S.R., Grigorieff, N. & Moore, M.J. Purifcation and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8, 426-439 (2002).
-
(2002)
RNA
, vol.8
, pp. 426-439
-
-
Jurica, M.S.1
Licklider, L.J.2
Gygi, S.R.3
Grigorieff, N.4
Purifcation, J.M.M.5
-
11
-
-
0036315512
-
Early organization of pre-mRNA during spliceosome assembly
-
Kent, O.A. & MacMillan, A.M. Early organization of pre-mRNA during spliceosome assembly. Nat. Struct. Biol. 9, 576-581 (2002).
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 576-581
-
-
Kent, O.A.1
MacMillan, A.M.2
-
12
-
-
0029400769
-
SnRNA interactions at 5′ and 3′ splice sites monitored by photoactivated crosslinking in yeast spliceosomes
-
Newman, A.J., Teigelkamp, S. & Beggs, J.D. snRNA interactions at 5′ and 3′ splice sites monitored by photoactivated crosslinking in yeast spliceosomes. RNA 1, 968-980 (1995).
-
(1995)
RNA
, vol.1
, pp. 968-980
-
-
Newman, A.J.1
Teigelkamp, S.2
Beggs., J.D.3
-
13
-
-
0022350602
-
Yeast mRNA splicing in vitro
-
Lin, R.J., Newman, A.J., Cheng, S.C. & Abelson, J. Yeast mRNA splicing in vitro. J. Biol. Chem. 260, 14780-14792 (1985).
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 14780-14792
-
-
Lin, R.J.1
Newman, A.J.2
Cheng, S.C.3
Abelson, J.4
-
14
-
-
0024710729
-
Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae
-
Vijayraghavan, U., Company, M. & Abelson, J. Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev. 3, 1206-1216 (1989).
-
(1989)
Genes Dev.
, vol.3
, pp. 1206-1216
-
-
Vijayraghavan, U.1
Company, M.2
Abelson, J.3
-
15
-
-
0037012922
-
Genomewide analysis of mRNA processing in yeast using splicing-specifc microarrays
-
Clark, T.A., Sugnet, C.W. & Ares, M. Jr. Genomewide analysis of mRNA processing in yeast using splicing-specifc microarrays. Science 296, 907-910 (2002).
-
(2002)
Science
, vol.296
, pp. 907-910
-
-
Clark, T.A.1
Sugnet, C.W.2
Ares, M.3
-
16
-
-
34247255773
-
Transcript specifcity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components
-
Pleiss, J.A., Whitworth, G.B., Bergkessel, M. & Guthrie, C. Transcript specifcity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components. PLoS Biol. 5, e90 (2007).
-
(2007)
PLoS Biol.
, vol.5
-
-
Pleiss, J.A.1
Whitworth, G.B.2
Bergkessel, M.3
Guthrie, C.4
-
17
-
-
0022747370
-
Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome
-
Vijayraghavan, U. et al. Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. EMBO J. 5, 1683-1695 (1986).
-
(1986)
EMBO J.
, vol.5
, pp. 1683-1695
-
-
Vijayraghavan, U.1
-
18
-
-
3042709638
-
Single-molecule enzymology of RNA: Essential functional groups impact catalysis from a distance
-
Rueda, D. et al. Single-molecule enzymology of RNA: essential functional groups impact catalysis from a distance. Proc. Natl. Acad. Sci. USA 101, 10066-10071 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10066-10071
-
-
Rueda, D.1
-
19
-
-
58149083620
-
A rugged free energy landscape separates multiple functional RNA folds throughout denaturation
-
Ditzler, M.A., Rueda, D., Mo, J., Hakansson, K. & Walter, N.G. A rugged free energy landscape separates multiple functional RNA folds throughout denaturation. Nucleic Acids Res. 36, 7088-7099 (2008).
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 7088-7099
-
-
Ditzler, M.A.1
Rueda, D.2
Mo, J.3
Hakansson, K.4
Walter, N.G.5
-
20
-
-
50049086369
-
Single vs. ribozyme molecules reveal dynamic and hierarchical folding toward catalysis
-
Pereira, M.J. et al. Single vs. ribozyme molecules reveal dynamic and hierarchical folding toward catalysis. J. Mol. Biol. 382, 496-509 (2008).
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 496-509
-
-
Pereira, M.J.1
-
21
-
-
58149085388
-
Leakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme
-
de Silva, C. & Walter, N.G. Leakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme. RNA 15, 76-84 (2009).
-
(2009)
RNA
, vol.15
, pp. 76-84
-
-
De Silva, C.1
Walter, N.G.2
-
22
-
-
0027488624
-
Isolation of new ribozymes from a large pool of random sequences
-
Bartel, D.P. & Szostak, J.W. Isolation of new ribozymes from a large pool of random sequences. Science 261, 1411-1418 (1993).
-
(1993)
Science
, vol.261
, pp. 1411-1418
-
-
Bartel, D.P.1
Szostak, J.W.2
-
23
-
-
33847051154
-
Identifcation of two distinct hybrid state intermediates on the ribosome
-
Munro, J.B., Altman, R.B., O'Connor, N. & Blanchard, S.C. Identifcation of two distinct hybrid state intermediates on the ribosome. Mol. Cell 25, 505-517 (2007).
-
(2007)
Mol. Cell
, vol.25
, pp. 505-517
-
-
Munro, J.B.1
Altman, R.B.2
O'Connor, N.3
Blanchard, S.C.4
-
24
-
-
33746747438
-
Analysis of single-molecule FRET trajectories using hidden Markov modeling
-
McKinney, S.A., Joo, C. & Ha, T. Analysis of single-molecule FRET trajectories using hidden Markov modeling. Biophys. J. 91, 1941-1951 (2006).
-
(2006)
Biophys. J.
, vol.91
, pp. 1941-1951
-
-
McKinney, S.A.1
Joo, C.2
Ha, T.3
-
25
-
-
44949117567
-
A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release
-
Schwer, B. A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release. Mol. Cell 30, 743-754 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 743-754
-
-
Schwer, B.1
-
26
-
-
38049077956
-
Visualizing the splicing of single pre-mRNA molecules in whole cell extract
-
Crawford, D.J., Hoskins, A.A., Friedman, L.J., Gelles, J. & Moore, M.J. Visualizing the splicing of single pre-mRNA molecules in whole cell extract. RNA 14, 170-179 (2008).
-
(2008)
RNA
, vol.14
, pp. 170-179
-
-
Crawford, D.J.1
Hoskins, A.A.2
Friedman, L.J.3
Gelles, J.4
Moore, M.J.5
-
27
-
-
0142215475
-
Global analysis of protein expression in yeast
-
Ghaemmaghami, S. et al. Global analysis of protein expression in yeast. Nature 425, 737-741 (2003).
-
(2003)
Nature
, vol.425
, pp. 737-741
-
-
Ghaemmaghami, S.1
-
28
-
-
0024325159
-
Identifcation of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing
-
Seraphin, B. & Rosbash, M. Identifcation of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing. Cell 59, 349-358 (1989).
-
(1989)
Cell
, vol.59
, pp. 349-358
-
-
Seraphin, B.1
Rosbash, M.2
-
29
-
-
0036158942
-
Composition and functional characterization of the yeast spliceosomal penta-snRNP
-
Stevens, S.W. et al. Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol. Cell 9, 31-44 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 31-44
-
-
Stevens, S.W.1
-
30
-
-
0033634673
-
Functional recognition of 5′ splice site by U4/U6.U5 tri-snRNP defnes a novel ATP-dependent step in early spliceosome assembly
-
Maroney, P.A., Romfo, C.M. & Nilsen, T.W. Functional recognition of 5′ splice site by U4/U6.U5 tri-snRNP defnes a novel ATP-dependent step in early spliceosome assembly. Mol. Cell 6, 317-328 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 317-328
-
-
Maroney, P.A.1
Romfo, C.M.2
Nilsen, T.W.3
-
31
-
-
52949135935
-
Mechanistic insights from reversible splicing catalysis
-
Smith, D.J. & Konarska, M.M. Mechanistic insights from reversible splicing catalysis. RNA 14, 1975-1978 (2008).
-
(2008)
RNA
, vol.14
, pp. 1975-1978
-
-
Smith, D.J.1
Konarska, M.M.2
-
32
-
-
46449086933
-
Both catalytic steps of nuclear pre-mRNA splicing are reversible
-
Tseng, C.K. & Cheng, S.C. Both catalytic steps of nuclear pre-mRNA splicing are reversible. Science 320, 1782-1784 (2008).
-
(2008)
Science
, vol.320
, pp. 1782-1784
-
-
Tseng, C.K.1
Cheng, S.C.2
-
33
-
-
44449125068
-
Spontaneous intersubunit rotation in single ribosomes
-
Cornish, P.V., Ermolenko, D.N., Noller, H.F. & Ha, T. Spontaneous intersubunit rotation in single ribosomes. Mol. Cell 30, 578-588 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 578-588
-
-
Cornish, P.V.1
Ermolenko, D.N.2
Noller, H.F.3
Ha, T.4
-
34
-
-
33751118289
-
An RNA ligase-mediated method for the effcient creation of large, synthetic RNAs
-
Stark, M.R., Pleiss, J.A., Deras, M., Scaringe, S.A. & Rader, S.D. An RNA ligase-mediated method for the effcient creation of large, synthetic RNAs. RNA 12, 2014-2019 (2006).
-
(2006)
RNA
, vol.12
, pp. 2014-2019
-
-
Stark, M.R.1
Pleiss, J.A.2
Deras, M.3
Scaringe, S.A.4
Rader, S.D.5
-
35
-
-
0036270848
-
Yeast pre-mRNA splicing: Methods, mechanisms, and machinery
-
Stevens, S.W. & Abelson, J. Yeast pre-mRNA splicing: methods, mechanisms, and machinery. Methods Enzymol. 351, 200-220 (2002).
-
(2002)
Methods Enzymol.
, vol.351
, pp. 200-220
-
-
Stevens, S.W.1
Abelson, J.2
-
36
-
-
0037057630
-
Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase
-
Ha, T. et al. Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase. Nature 419, 638-641 (2002).
-
(2002)
Nature
, vol.419
, pp. 638-641
-
-
Ha, T.1
-
37
-
-
0041821716
-
Single-molecule kinetics of lambda exonuclease reveal base dependence and dynamic disorder
-
van Oijen, A.M. et al. Single-molecule kinetics of lambda exonuclease reveal base dependence and dynamic disorder. Science 301, 1235-1238 (2003).
-
(2003)
Science
, vol.301
, pp. 1235-1238
-
-
Van Oijen, A.M.1
-
38
-
-
0037165996
-
Correlating structural dynamics and function in single ribozyme molecules
-
Zhuang, X. et al. Correlating structural dynamics and function in single ribozyme molecules. Science 296, 1473-1476 (2002).
-
(2002)
Science
, vol.296
, pp. 1473-1476
-
-
Zhuang, X.1
-
39
-
-
33750295496
-
Nonblinking and long-lasting single-molecule fuorescence imaging
-
Rasnik, I., McKinney, S.A. & Ha, T. Nonblinking and long-lasting single-molecule fuorescence imaging. Nat. Methods 3, 891-893 (2006).
-
(2006)
Nat. Methods
, vol.3
, pp. 891-893
-
-
Rasnik, I.1
McKinney, S.A.2
Ha, T.3
|