Coupled in vitro synthesis and splicing of RNA polymerase II transcripts

RNA

Volumn 6, Issue 9, 2000, Pages 1325-1334

  Ghosh, Sagarmoy ^a   Garcia Blanco, Mariano A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cotranscriptional splicing; Rate of splicing; RNA polymerase II; T7 RNA polymerase; Transcription

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; MESSENGER RNA;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DNA TEMPLATE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RNA PROCESSING; RNA SPLICING; RNA SYNTHESIS; RNA TRANSCRIPTION;

BASE SEQUENCE; DNA, VIRAL; HELA CELLS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; RNA POLYMERASE II; RNA PRECURSORS; RNA SPLICING; TRANSCRIPTION, GENETIC;

EID: 0033834946     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838200992537     Document Type: Article

References (37)

1. Splicing of Balbani ring 1 gene pre-mRNA occurs simultaneously with transcription
2. Coupling RNA polymerase II transcription with pre-mRNA processing
3. Splice site selection, rate of splicing, and alternative splicing of nascent transcripts
4. TAR RNA decoys inhibit tat-activated HIV-1 transcription after preinitiation complex formation
5. An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicing
6. mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain
7. A CTD function linking transcription to splicing
8. Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer
9. Functional association between promoter structure and transcript alternative splicing
10. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
11. A functional interaction between the carboxy-terminal domain of RNA polymerase II and pre-mRNA splicing
12. Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II
13. Positive patches and negative noodles: Linking RNA processing to transcription?
14. Cofactor requirements of splicing of purified messenger RNA precursors
15. Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts
16. RNA polymerase II is an essential mRNA polyadenylation factor
17. Phosphorylated RNA polymerase II stimulates pre-mRNA splicing
18. A nuclear cap binding protein complex involved in pre-mRNA splicing
19. In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism
20. Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA
21. Accurate in vitro splicing of β-globin RNA
22. Recognition of cap structure in splicing in vitro of mRNA precursors
23. The C-terminal domain of RNA polymerase II couples mRNA processing to transcription
24. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo
25. Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-end formation
26. Transcription units as RNA processing units
27. A conserved epitope on a subset of SR proteins defines a larger family of pre-mRNA splicing factors
28. Splicing of adenovirus RNA in a cell-free transcription system
29. The 5' and 3' splice sites come together via a three dimensional diffusion mechanism
30. A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II
31. Co-transcriptional commitment to alternative splice site selection
32. Pre-mRNA processing and the CTD of RNA polymerase II: The tail that wags the dog?
33. Functions of SR and Tra2 proteins in pre-mRNA splicing regulation
34. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
35. Transcription and processing of adenoviral RNA by extracts from HeLa cells
36. The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins
37. Localization of pre-mRNA splicing in mammalian nuclei