메뉴 건너뛰기




Volumn 36, Issue , 2002, Pages 333-360

Allosteric cascade of spliceosome activation

Author keywords

Intron; pre mRNA; RNA; snRNP; Splicing

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MESSENGER RNA PRECURSOR; SMALL NUCLEAR RNA;

EID: 0036948420     PISSN: 00664197     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.genet.36.043002.091635     Document Type: Review
Times cited : (297)

References (178)
  • 1
    • 0028273768 scopus 로고
    • The yeast MUD2 protein: An interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition
    • Abovich N, Liao XC, Rosbash M. 1994. The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition. Genes Dev. 8:843-54
    • (1994) Genes Dev. , vol.8 , pp. 843-854
    • Abovich, N.1    Liao, X.C.2    Rosbash, M.3
  • 2
    • 0030911051 scopus 로고    scopus 로고
    • Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
    • Abovich N, Rosbash M. 1997. Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89:403-12
    • (1997) Cell , vol.89 , pp. 403-412
    • Abovich, N.1    Rosbash, M.2
  • 3
    • 0037036402 scopus 로고    scopus 로고
    • Probing interactions between the U2 snRNP and the DEAD-box protein Prp5
    • Abu Dayyeh BK, Quan TK, Castro M, Ruby SW. 2002. Probing interactions between the U2 snRNP and the DEAD-box protein Prp5. J. Biol. Chem. 277:20221-33
    • (2002) J. Biol. Chem. , vol.277 , pp. 20221-20233
    • Abu Dayyeh, B.K.1    Quan, T.K.2    Castro, M.3    Ruby, S.W.4
  • 4
    • 0034956337 scopus 로고    scopus 로고
    • ATP-dependent interaction of yeast U5 snRNA loop 1 with the 5′ splice site
    • Alvi RK, Lund M, O'Keefe RT. 2001. ATP-dependent interaction of yeast U5 snRNA loop 1 with the 5′ splice site. RNA 7:1013-23
    • (2001) RNA , vol.7 , pp. 1013-1023
    • Alvi, R.K.1    Lund, M.2    O'Keefe, R.T.3
  • 5
    • 0029167994 scopus 로고
    • Rearrangement of snRNA structure during assembly and function of the spliceosome
    • Ares M Jr, Weiser B. 1995. Rearrangement of snRNA structure during assembly and function of the spliceosome. Prog. Nucleic Acids Res. Mol. Biol. 50:131-59
    • (1995) Prog. Nucleic Acids Res. Mol. Biol. , vol.50 , pp. 131-159
    • Ares M., Jr.1    Weiser, B.2
  • 6
    • 0030671163 scopus 로고    scopus 로고
    • Prp43: An RNA helicase-like factor involved in spliceosome disassembly
    • Arenas JE, Abelson JN. 1997. Prp43: An RNA helicase-like factor involved in spliceosome disassembly. Proc. Natl. Acad. Sci. USA 94:11798-802
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11798-11802
    • Arenas, J.E.1    Abelson, J.N.2
  • 7
    • 0029949698 scopus 로고    scopus 로고
    • Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA
    • Arning S, Grüter P, Bilbe G, Krämer A. 1996. Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA. RNA 2:794-810
    • (1996) RNA , vol.2 , pp. 794-810
    • Arning, S.1    Grüter, P.2    Bilbe, G.3    Krämer, A.4
  • 8
    • 0035870716 scopus 로고    scopus 로고
    • Sequences upstream of the branch site are required to form helix II between U2 and U6 snRNA in a trans-splicing reaction
    • Ast G, Pavelitz T, Weiner AM. 2001. Sequences upstream of the branch site are required to form helix II between U2 and U6 snRNA in a trans-splicing reaction. Nucleic Acids Res. 29:1741-49
    • (2001) Nucleic Acids Res. , vol.29 , pp. 1741-1749
    • Ast, G.1    Pavelitz, T.2    Weiner, A.M.3
  • 9
    • 0030914332 scopus 로고    scopus 로고
    • A novel U1/U5 interaction indicates proximity between U1 and U5 snRNAs during an early step of mRNA splicing
    • Ast G, Weiner AM. 1997. A novel U1/U5 interaction indicates proximity between U1 and U5 snRNAs during an early step of mRNA splicing. RNA 3:371-81
    • (1997) RNA , vol.3 , pp. 371-381
    • Ast, G.1    Weiner, A.M.2
  • 10
    • 0035903211 scopus 로고    scopus 로고
    • New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing
    • Awashti S, Palmer R, Castro M, Mobarak CD, Ruby SW. 2001. New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J. Biol. Chem. 276:31004-15
    • (2001) J. Biol. Chem. , vol.276 , pp. 31004-31015
    • Awashti, S.1    Palmer, R.2    Castro, M.3    Mobarak, C.D.4    Ruby, S.W.5
  • 11
    • 0031016867 scopus 로고    scopus 로고
    • Mutations within the yeast U4/U6 snRNP protein Prp4 affect a late stage of spliceosome assembly
    • Ayadi L, Miller M, Banroques J. 1997. Mutations within the yeast U4/U6 snRNP protein Prp4 affect a late stage of spliceosome assembly. RNA 3:197-209
    • (1997) RNA , vol.3 , pp. 197-209
    • Ayadi, L.1    Miller, M.2    Banroques, J.3
  • 12
    • 0032484029 scopus 로고    scopus 로고
    • Functional and structural characterization of the Prp3 binding domain of the yeast Prp4 splicing factor
    • Ayadi L, Callebaut I, Saguez C, Villa T, Mornon J-P, Banroques J. 1998. Functional and structural characterization of the Prp3 binding domain of the yeast Prp4 splicing factor. J. Mol. Biol. 284:673-87
    • (1998) J. Mol. Biol. , vol.284 , pp. 673-687
    • Ayadi, L.1    Callebaut, I.2    Saguez, C.3    Villa, T.4    Mornon, J.-P.5    Banroques, J.6
  • 13
    • 0034533307 scopus 로고    scopus 로고
    • Genetic and physical interaction between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae
    • Ben-Yehuda S, Dix I, Russell CS, McGarvey M, Beggs JD, Kupiec M. 2000. Genetic and physical interaction between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156:1503-17
    • (2000) Genetics , vol.156 , pp. 1503-1517
    • Ben-Yehuda, S.1    Dix, I.2    Russell, C.S.3    McGarvey, M.4    Beggs, J.D.5    Kupiec, M.6
  • 14
    • 0028895417 scopus 로고
    • Exon recognition in vertebrate splicing
    • Berget SM. 1995. Exon recognition in vertebrate splicing. J. Biol. Chem. 270:2411-14
    • (1995) J. Biol. Chem. , vol.270 , pp. 2411-2414
    • Berget, S.M.1
  • 15
    • 0032521186 scopus 로고    scopus 로고
    • A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
    • Berglund JA, Abovich N, Rosbash M. 1998. A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. Genes Dev. 12:858-67
    • (1998) Genes Dev. , vol.12 , pp. 858-867
    • Berglund, J.A.1    Abovich, N.2    Rosbash, M.3
  • 16
    • 0030696675 scopus 로고    scopus 로고
    • The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC
    • Berglund JA, Chua K, Abovich N, Reed R, Rosbash M. 1997. The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC. Cell 89:781-87
    • (1997) Cell , vol.89 , pp. 781-787
    • Berglund, J.A.1    Chua, K.2    Abovich, N.3    Reed, R.4    Rosbash, M.5
  • 17
    • 0031823231 scopus 로고    scopus 로고
    • The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequence
    • Berglund JA, Fleming ML, Rosbash M. 1998. The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequence. RNA 4:998-1006
    • (1998) RNA , vol.4 , pp. 998-1006
    • Berglund, J.A.1    Fleming, M.L.2    Rosbash, M.3
  • 18
    • 0021799778 scopus 로고
    • The "spliceosome": Yeast pre-messenger RNA associates with a 40S complex in a splicing-dependent reaction
    • Brody E, Abelson J. 1985. The "spliceosome": yeast pre-messenger RNA associates with a 40S complex in a splicing-dependent reaction. Science 228:963-67
    • (1985) Science , vol.228 , pp. 963-967
    • Brody, E.1    Abelson, J.2
  • 19
    • 0029286626 scopus 로고
    • An element in human U6 RNA destabilizes the U4/U6 spliceosomal RNA complex
    • Brow DA, Vidaver RM. 1995. An element in human U6 RNA destabilizes the U4/U6 spliceosomal RNA complex. RNA 1:122-31
    • (1995) RNA , vol.1 , pp. 122-131
    • Brow, D.A.1    Vidaver, R.M.2
  • 20
    • 0001468848 scopus 로고    scopus 로고
    • Splicing of precursors to mRNAs by the spliceosomes
    • ed. RF Gesteland, TR Cech, JF Atkins. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press
    • Burge CB, Tuschl TA, Sharp PA. 1999. Splicing of precursors to mRNAs by the spliceosomes. In RNA World, ed. RF Gesteland, TR Cech, JF Atkins, pp. 525-60. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press
    • (1999) RNA World , pp. 525-560
    • Burge, C.B.1    Tuschl, T.A.2    Sharp, P.A.3
  • 21
    • 0036143714 scopus 로고    scopus 로고
    • Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae
    • Burns CG, Ohi R, Mehta S, O'Toole ET, Winey M, et al. 2002. Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae. Mol. Cell. Biol. 22:801-15
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 801-815
    • Burns, C.G.1    Ohi, R.2    Mehta, S.3    O'Toole, E.T.4    Winey, M.5
  • 22
    • 0035367070 scopus 로고    scopus 로고
    • Structure and function of the small ribozymes
    • Butcher SE. 2001. Structure and function of the small ribozymes. Curr. Opin. Struct. Biol. 11:315-20
    • (2001) Curr. Opin. Struct. Biol. , vol.11 , pp. 315-320
    • Butcher, S.E.1
  • 23
    • 0036534129 scopus 로고    scopus 로고
    • Alternative splicing: Multiple control mechanisms and involvement in human disease
    • Cáceres JF, Kornblihtt AR. 2002. Alternative splicing: multiple control mechanisms and involvement in human disease. Trends Genet. 18:186-93
    • (2002) Trends Genet. , vol.18 , pp. 186-193
    • Cáceres, J.F.1    Kornblihtt, A.R.2
  • 24
    • 0032476603 scopus 로고    scopus 로고
    • The yeast U2A′/U2B″ complex is required for pre-spliceosome formation
    • Caspary F, Séraphin B. 1998. The yeast U2A′/U2B″ complex is required for pre-spliceosome formation. EMBO J. 17:6348-58
    • (1998) EMBO J. , vol.17 , pp. 6348-6358
    • Caspary, F.1    Séraphin, B.2
  • 25
    • 0033564206 scopus 로고    scopus 로고
    • Partial purification of the yeast U2 snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome formation
    • Caspary F, Shevchenko A, Wilm M, Séraphin B. 1999. Partial purification of the yeast U2 snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome formation. EMBO J. 18:3463-74
    • (1999) EMBO J. , vol.18 , pp. 3463-3474
    • Caspary, F.1    Shevchenko, A.2    Wilm, M.3    Séraphin, B.4
  • 26
    • 18244377189 scopus 로고    scopus 로고
    • Mutations in HPRP3, a third member of pre-mRNA splicing factor genes, implicated in autosomal dominant retinitis pigmentosa
    • Chakarova CF, Hims MM, Bolz H, Abu-Safieh L, Patel RJ, et al. 2002. Mutations in HPRP3, a third member of pre-mRNA splicing factor genes, implicated in autosomal dominant retinitis pigmentosa. Hum. Mol. Genet. 11:87-92
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 87-92
    • Chakarova, C.F.1    Hims, M.M.2    Bolz, H.3    Abu-Safieh, L.4    Patel, R.J.5
  • 27
    • 0037082435 scopus 로고    scopus 로고
    • Functional and physical interactions between components of the Prp19p-associated complex
    • Chen C-H, Yu W-C, Tsao TY, Wang L-Y, Chen H-R, et al. 2002. Functional and physical interactions between components of the Prp19p-associated complex. Nucleic Acids Res. 30:1029-37
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1029-1037
    • Chen, C.-H.1    Yu, W.-C.2    Tsao, T.Y.3    Wang, L.-Y.4    Chen, H.-R.5
  • 28
    • 0035105921 scopus 로고    scopus 로고
    • Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor
    • Chen JY, Stands L, Staley JP, Jackups RR, Latus LJ, Chang T-H. 2001. Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor. Mol. Cell 7:227-32
    • (2001) Mol. Cell , vol.7 , pp. 227-232
    • Chen, J.Y.1    Stands, L.2    Staley, J.P.3    Jackups, R.R.4    Latus, L.J.5    Chang, T.-H.6
  • 29
    • 0023449728 scopus 로고
    • Spliceosome assembly in yeast
    • Cheng S-C, Abelson J. 1987. Spliceosome assembly in yeast. Genes Dev. 1:1014-27
    • (1987) Genes Dev. , vol.1 , pp. 1014-1027
    • Cheng, S.-C.1    Abelson, J.2
  • 30
    • 0032877215 scopus 로고    scopus 로고
    • Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition
    • Chung S, McLean MR, Rymond BC. 1999. Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition. RNA 5:1042-54
    • (1999) RNA , vol.5 , pp. 1042-1054
    • Chung, S.1    McLean, M.R.2    Rymond, B.C.3
  • 31
    • 0029775561 scopus 로고    scopus 로고
    • The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex
    • Colot HV, Stutz F, Rosbash M. 1996. The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex. Genes Dev. 10:1699-708
    • (1996) Genes Dev. , vol.10 , pp. 1699-1708
    • Colot, H.V.1    Stutz, F.2    Rosbash, M.3
  • 32
    • 0027273672 scopus 로고
    • A cold-sensitive mutation in 16S rRNA provides evidence for helical switching in ribosome assembly
    • Dammel C, Noller H. 1993. A cold-sensitive mutation in 16S rRNA provides evidence for helical switching in ribosome assembly. Genes Dev. 7:660-70
    • (1993) Genes Dev. , vol.7 , pp. 660-670
    • Dammel, C.1    Noller, H.2
  • 33
    • 0033636518 scopus 로고    scopus 로고
    • Functional association of U2 snRNP with the ATP-independent spliceosomal complex E
    • Das R, Zhou Z, Reed R. 2000. Functional association of U2 snRNP with the ATP-independent spliceosomal complex E. Mol. Cell 5:779-87
    • (2000) Mol. Cell , vol.5 , pp. 779-787
    • Das, R.1    Zhou, Z.2    Reed, R.3
  • 34
    • 0035037961 scopus 로고    scopus 로고
    • Yeast U1 snRNP-pre-mRNA complex formation without U1 snRNA-pre-mRNA base pairing
    • Du H, Rosbash M. 2001. Yeast U1 snRNP-pre-mRNA complex formation without U1 snRNA-pre-mRNA base pairing. RNA 7:133-42
    • (2001) RNA , vol.7 , pp. 133-142
    • Du, H.1    Rosbash, M.2
  • 35
    • 0033864702 scopus 로고    scopus 로고
    • Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins
    • Edwalds-Gilbert G, Kim D-H, Kim S-H, Tseng Y-H, Yu Y, Lin R-J. 2000. Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins. RNA 6:1106-19
    • (2000) RNA , vol.6 , pp. 1106-1119
    • Edwalds-Gilbert, G.1    Kim, D.-H.2    Kim, S.-H.3    Tseng, Y.-H.4    Yu, Y.5    Lin, R.-J.6
  • 36
    • 0030611640 scopus 로고    scopus 로고
    • U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
    • Fleckner J, Zhang M, Valcárcel J, Green MR. 1997. U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. Genes Dev. 11:1864-72
    • (1997) Genes Dev. , vol.11 , pp. 1864-1872
    • Fleckner, J.1    Zhang, M.2    Valcárcel, J.3    Green, M.R.4
  • 37
    • 0033568197 scopus 로고    scopus 로고
    • Luc7p, a novel yeast U1 snRNP protein with a role in 5′ splice site recognition
    • Fortes P, Bilbao-Cortés D, Fornerod M, Rigaut G, Raymond W, et al. 1999. Luc7p, a novel yeast U1 snRNP protein with a role in 5′ splice site recognition. Genes Dev. 13:2425-38
    • (1999) Genes Dev. , vol.13 , pp. 2425-2438
    • Fortes, P.1    Bilbao-Cortés, D.2    Fornerod, M.3    Rigaut, G.4    Raymond, W.5
  • 39
    • 0028144641 scopus 로고
    • A stem-loop in U6 RNA defines a conformational switch required for pre-messenger RNA splicing
    • Fortner DM, Troy RG, Brow DA. 1994. A stem-loop in U6 RNA defines a conformational switch required for pre-messenger RNA splicing. Genes Dev. 8:221-33
    • (1994) Genes Dev. , vol.8 , pp. 221-233
    • Fortner, D.M.1    Troy, R.G.2    Brow, D.A.3
  • 40
    • 0022413541 scopus 로고
    • Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences
    • Frendewey D, Keller W. 1985. Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences. Cell 42:355-67
    • (1985) Cell , vol.42 , pp. 355-367
    • Frendewey, D.1    Keller, W.2
  • 41
    • 0029951308 scopus 로고    scopus 로고
    • Conditional mutants of the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing
    • Fresco LD, Buratowski S. 1996. Conditional mutants of the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing. RNA 2:584-96
    • (1996) RNA , vol.2 , pp. 584-596
    • Fresco, L.D.1    Buratowski, S.2
  • 42
    • 0035104772 scopus 로고    scopus 로고
    • Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome
    • Frilander MJ, Steitz JA. 2001. Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome. Mol. Cell 7:217-26
    • (2001) Mol. Cell , vol.7 , pp. 217-226
    • Frilander, M.J.1    Steitz, J.A.2
  • 43
    • 0030963019 scopus 로고    scopus 로고
    • Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens
    • Fromont-Racine M, Rain J-C, Legrain P. 1997. Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Nat. Genet. 16:277-82
    • (1997) Nat. Genet. , vol.16 , pp. 277-282
    • Fromont-Racine, M.1    Rain, J.-C.2    Legrain, P.3
  • 44
    • 0033965261 scopus 로고    scopus 로고
    • Metal ion catalysis during the exonligation step of nuclear pre-mRNA splicing: Extending the parallels between the spliceosome and group II introns
    • Gordon PM, Sontheimer EJ, Piccirilli JA. 2000. Metal ion catalysis during the exonligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns. RNA 6:199-205
    • (2000) RNA , vol.6 , pp. 199-205
    • Gordon, P.M.1    Sontheimer, E.J.2    Piccirilli, J.A.3
  • 45
    • 0035052524 scopus 로고    scopus 로고
    • A novel yeast U2 snRNP protein, Snu17, is required for the first catalytic step of splicing and for progression of spliceosome assembly
    • Gottschalk A, Bartels C, Neubauer G, Lührmann R, Fabrizio P. 2001. A novel yeast U2 snRNP protein, Snu17, is required for the first catalytic step of splicing and for progression of spliceosome assembly. Mol. Cell. Biol. 21:3037-46
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3037-3046
    • Gottschalk, A.1    Bartels, C.2    Neubauer, G.3    Lührmann, R.4    Fabrizio, P.5
  • 46
    • 0035161659 scopus 로고    scopus 로고
    • The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p
    • Gottschalk A, Kastner B, Lührmann R, Fabrizio P. 2001. The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7:1554-66
    • (2001) RNA , vol.7 , pp. 1554-1566
    • Gottschalk, A.1    Kastner, B.2    Lührmann, R.3    Fabrizio, P.4
  • 47
    • 0033575711 scopus 로고    scopus 로고
    • Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP
    • Gottschalk A, Neubauer G, Banroques J, Mann M, Lührmann R, Fabrizio P. 1999. Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. EMBO J. 18:4535-48
    • (1999) EMBO J. , vol.18 , pp. 4535-4548
    • Gottschalk, A.1    Neubauer, G.2    Banroques, J.3    Mann, M.4    Lührmann, R.5    Fabrizio, P.6
  • 48
    • 0031899237 scopus 로고    scopus 로고
    • A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins
    • Gottschalk A, Tang J, Puig O, Salgado J, Neubauer G, et al. 1998. A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4:374-93
    • (1998) RNA , vol.4 , pp. 374-393
    • Gottschalk, A.1    Tang, J.2    Puig, O.3    Salgado, J.4    Neubauer, G.5
  • 49
    • 0030044836 scopus 로고    scopus 로고
    • Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A
    • Gozani O, Feld R, Reed R. 1996. Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A. Genes Dev. 10:233-43
    • (1996) Genes Dev. , vol.10 , pp. 233-243
    • Gozani, O.1    Feld, R.2    Reed, R.3
  • 50
    • 0031878108 scopus 로고    scopus 로고
    • A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site
    • Gozani O, Potashkin J, Reed R. 1998. A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site. Mol. Cell. Biol. 18:4752-60
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4752-4760
    • Gozani, O.1    Potashkin, J.2    Reed, R.3
  • 51
    • 0022354874 scopus 로고
    • A multicomponent complex is involved in the splicing of messenger RNA precursors
    • Grabowski PJ, Seiler SR, Sharp PA. 1985. A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell 42:345-53
    • (1985) Cell , vol.42 , pp. 345-353
    • Grabowski, P.J.1    Seiler, S.R.2    Sharp, P.A.3
  • 52
    • 0033835333 scopus 로고    scopus 로고
    • Sorting out the complexity of SR protein function
    • Gravely BR. 2000. Sorting out the complexity of SR protein function. RNA 6:1197-211
    • (2000) RNA , vol.6 , pp. 1197-1211
    • Gravely, B.R.1
  • 53
    • 0025639012 scopus 로고
    • Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles
    • Hausner T-P, Giglio LM, Weiner AM. 1990. Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles. Genes Dev. 4:2146-56
    • (1990) Genes Dev. , vol.4 , pp. 2146-2156
    • Hausner, T.-P.1    Giglio, L.M.2    Weiner, A.M.3
  • 54
    • 0025137186 scopus 로고
    • U1-specific protein C needed for efficient complex formation of U1 snRNP with a 5′ splice site
    • Heinrichs V, Bach M, Winkelmann G, Lührmann R. 1990. U1-specific protein C needed for efficient complex formation of U1 snRNP with a 5′ splice site. Science 247:69-72
    • (1990) Science , vol.247 , pp. 69-72
    • Heinrichs, V.1    Bach, M.2    Winkelmann, G.3    Lührmann, R.4
  • 55
    • 0021026456 scopus 로고
    • Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts
    • Hernandez N, Keller W. 1983. Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts. Cell 35:89-99
    • (1983) Cell , vol.35 , pp. 89-99
    • Hernandez, N.1    Keller, W.2
  • 57
    • 0031976033 scopus 로고    scopus 로고
    • Conservation of structure and subunit interactions in yeast homologs of splicing factor 3b (SF3b) subunits
    • Igel H, Wells S, Perriman R, Ares M Jr. 1998. Conservation of structure and subunit interactions in yeast homologs of splicing factor 3b (SF3b) subunits. RNA 4:1-10
    • (1998) RNA , vol.4 , pp. 1-10
    • Igel, H.1    Wells, S.2    Perriman, R.3    Ares M., Jr.4
  • 58
    • 0035256812 scopus 로고    scopus 로고
    • The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5′ splice site through its ATPase site
    • Ismaïli N, Sha M, Gustafson EH, Konarska MM. 2001. The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5′ splice site through its ATPase site. RNA 7:182-93
    • (2001) RNA , vol.7 , pp. 182-193
    • Ismaïli, N.1    Sha, M.2    Gustafson, E.H.3    Konarska, M.M.4
  • 59
    • 0035423681 scopus 로고    scopus 로고
    • Characterization of U4 and U6 interactions with the 5′ splice site using a S. cerevisiae in vitro trans-splicing system
    • Johnson TL, Abelson J. 2001. Characterization of U4 and U6 interactions with the 5′ splice site using a S. cerevisiae in vitro trans-splicing system. Genes Dev. 15:1957-70
    • (2001) Genes Dev. , vol.15 , pp. 1957-1970
    • Johnson, T.L.1    Abelson, J.2
  • 60
    • 0027923620 scopus 로고
    • Involvement of U6 snRNA in 5′ splice site selection
    • Kandels-Lewis S, Seraphin B. 1993. Involvement of U6 snRNA in 5′ splice site selection, Science 262:2035-39
    • (1993) Science , vol.262 , pp. 2035-2039
    • Kandels-Lewis, S.1    Seraphin, B.2
  • 61
    • 0030027483 scopus 로고    scopus 로고
    • Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle
    • Kao H-Y, Siliciano PG. 1996. Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle. Mol. Cell. Biol. 16:960-67
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 960-967
    • Kao, H.-Y.1    Siliciano, P.G.2
  • 62
    • 0034663604 scopus 로고    scopus 로고
    • Analysis of the splicing machinery in fission yeast: A comparison with budding yeast and mammals
    • Käufer NF, Potashkin J. 2000. Analysis of the splicing machinery in fission yeast: a comparison with budding yeast and mammals. Nucleic Acids Res. 28:3003-10
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3003-3010
    • Käufer, N.F.1    Potashkin, J.2
  • 63
    • 0002690513 scopus 로고    scopus 로고
    • Site-specific crosslinks of yeast U6 snRNA to the pre-mRNA near the 5′ splice site
    • Kim CH, Abelson J. 1996. Site-specific crosslinks of yeast U6 snRNA to the pre-mRNA near the 5′ splice site. RNA 2:995-1010
    • (1996) RNA , vol.2 , pp. 995-1010
    • Kim, C.H.1    Abelson, J.2
  • 64
    • 0034666330 scopus 로고    scopus 로고
    • Human RNA lariat debranching enzyme cDNA complements the phenotypes of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1 mutants
    • Kim JW, Kim HC, Kim GM, Yang JM, Boeke JD, Nam K. 2000. Human RNA lariat debranching enzyme cDNA complements the phenotypes of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1 mutants. Nucleic Acids Res. 28:3666-73
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3666-3673
    • Kim, J.W.1    Kim, H.C.2    Kim, G.M.3    Yang, J.M.4    Boeke, J.D.5    Nam, K.6
  • 65
    • 0033056712 scopus 로고    scopus 로고
    • The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex
    • Kim D-H, Rossi JJ. 1999. The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex. RNA 5:959-71
    • (1999) RNA , vol.5 , pp. 959-971
    • Kim, D.-H.1    Rossi, J.J.2
  • 66
    • 0029965552 scopus 로고    scopus 로고
    • Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing
    • Kim S-H, Lin R-J. 1996. Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing. Mol. Cell. Biol. 16:6810-19
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6810-6819
    • Kim, S.-H.1    Lin, R.-J.2
  • 67
    • 0035177309 scopus 로고    scopus 로고
    • Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase
    • Kistler AL, Guthrie C. 2001. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase. Genes Dev. 15:42-49
    • (2001) Genes Dev. , vol.15 , pp. 42-49
    • Kistler, A.L.1    Guthrie, C.2
  • 68
    • 0022549635 scopus 로고
    • Electrophoretic separation of complexes involved in the splicing of precursors to mRNA
    • Konarska MM, Sharp PA. 1986. Electrophoretic separation of complexes involved in the splicing of precursors to mRNA. Cell 46:845-55
    • (1986) Cell , vol.46 , pp. 845-855
    • Konarska, M.M.1    Sharp, P.A.2
  • 69
    • 0011990527 scopus 로고
    • Association of U2, U4, U5, and U6 small nuclear ribonucleoproteins in a spliceosome-type complex in absence of precursor mRNA
    • Konarska MM, Sharp PA. 1988. Association of U2, U4, U5, and U6 small nuclear ribonucleoproteins in a spliceosome-type complex in absence of precursor mRNA. Proc. Natl. Acad. Sci. USA 85:5459-62
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5459-5462
    • Konarska, M.M.1    Sharp, P.A.2
  • 70
    • 0021223245 scopus 로고
    • Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro
    • Krainer AR, Maniatis T, Ruskin B, Green MR. 1984. Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell 36:993-1005
    • (1984) Cell , vol.36 , pp. 993-1005
    • Krainer, A.R.1    Maniatis, T.2    Ruskin, B.3    Green, M.R.4
  • 71
    • 0029891101 scopus 로고    scopus 로고
    • The structure and function of proteins involved in mammalian pre-mRNA splicing
    • Krämer A. 1996. The structure and function of proteins involved in mammalian pre-mRNA splicing. Annu. Rev. Biochem. 65:367-409
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 367-409
    • Krämer, A.1
  • 72
    • 0033612569 scopus 로고    scopus 로고
    • Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP
    • Krämer A, Grüter P, Gröning K, Kastner B. 1999. Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP. J. Cell Biol. 145:1355-68
    • (1999) J. Cell Biol. , vol.145 , pp. 1355-1368
    • Krämer, A.1    Grüter, P.2    Gröning, K.3    Kastner, B.4
  • 73
    • 0033900068 scopus 로고    scopus 로고
    • Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation
    • Kuhn AN, Brow DA. 2000. Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155:1667-82
    • (2000) Genetics , vol.155 , pp. 1667-1682
    • Kuhn, A.N.1    Brow, D.A.2
  • 74
    • 0033047503 scopus 로고    scopus 로고
    • Splicing factor Prp8 governs U4/U6 unwinding during activation of the spliceosome
    • Kuhn AN, Li Z, Brow DA. 1999. Splicing factor Prp8 governs U4/U6 unwinding during activation of the spliceosome. Mol. Cell 3:65-75
    • (1999) Mol. Cell , vol.3 , pp. 65-75
    • Kuhn, A.N.1    Li, Z.2    Brow, D.A.3
  • 75
    • 0037047049 scopus 로고    scopus 로고
    • Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation
    • Kuhn AN, Reichl EM, Brow DA. 2002. Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation. Proc. Natl. Acad. Sci. USA 99:9145-49
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 9145-9149
    • Kuhn, A.N.1    Reichl, E.M.2    Brow, D.A.3
  • 76
    • 0032515969 scopus 로고    scopus 로고
    • The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro
    • Laggerbauer B, Achsel T, Lührmann R. 1998. The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro. Proc. Natl. Acad. Sci. USA 95:4188-92
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 4188-4192
    • Laggerbauer, B.1    Achsel, T.2    Lührmann, R.3
  • 77
    • 0029782402 scopus 로고    scopus 로고
    • The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases
    • Lauber J, Fabrizio P, Teigelkamp S, Lane WS, Hartmann E, Lührmann R. 1996. The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases. EMBO J. 15:4001-15
    • (1996) EMBO J. , vol.15 , pp. 4001-4015
    • Lauber, J.1    Fabrizio, P.2    Teigelkamp, S.3    Lane, W.S.4    Hartmann, E.5    Lührmann, R.6
  • 78
    • 0023695462 scopus 로고
    • Early commitment of yeast pre-mRNA to the spliceosome pathway
    • Legrain P, Séraphin B, Rosbash M. 1988. Early commitment of yeast pre-mRNA to the spliceosome pathway. Mol. Cell. Biol. 8:3755-60
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3755-3760
    • Legrain, P.1    Séraphin, B.2    Rosbash, M.3
  • 79
    • 0027739852 scopus 로고
    • Mutations in U6 snRNA that alter splice site specificity: Implications for the active site
    • Lesser CF, Guthrie C. 1993. Mutations in U6 snRNA that alter splice site specificity: implications for the active site. Science 262:1982-88
    • (1993) Science , vol.262 , pp. 1982-1988
    • Lesser, C.F.1    Guthrie, C.2
  • 80
    • 0029790606 scopus 로고    scopus 로고
    • A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing
    • Lewis JD, Görlich D, Mattaj IW. 1996. A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing. Nucleic Acids Res. 24:3332-6
    • (1996) Nucleic Acids Res. , vol.24 , pp. 3332-3336
    • Lewis, J.D.1    Görlich, D.2    Mattaj, I.W.3
  • 81
    • 0029958501 scopus 로고    scopus 로고
    • A spontaneous duplication in U6 spliceosomal RNA uncouples the early and late functions of the ACAGA element in vivo
    • Li Z, Brow DA. 1996. A spontaneous duplication in U6 spliceosomal RNA uncouples the early and late functions of the ACAGA element in vivo. RNA 2:879-94
    • (1996) RNA , vol.2 , pp. 879-894
    • Li, Z.1    Brow, D.A.2
  • 83
    • 0027241224 scopus 로고
    • An enhancer screen identifies a gene that encodes the yeast U1A snRNP protein: Implications for snRNP protein function in pre-mRNA splicing
    • Liao XC, Tang J, Rosbash M. 1993. An enhancer screen identifies a gene that encodes the yeast U1A snRNP protein: implications for snRNP protein function in pre-mRNA splicing. Genes Dev. 7:419-28
    • (1993) Genes Dev. , vol.7 , pp. 419-428
    • Liao, X.C.1    Tang, J.2    Rosbash, M.3
  • 84
    • 0035180388 scopus 로고    scopus 로고
    • Multiple roles for the yeast SUB2/yUAP56 gene in splicing
    • Libri D, Graziani N, Saguez C, Boulay J. 2001. Multiple roles for the yeast SUB2/yUAP56 gene in splicing. Genes Dev. 15:36-41
    • (2001) Genes Dev. , vol.15 , pp. 36-41
    • Libri, D.1    Graziani, N.2    Saguez, C.3    Boulay, J.4
  • 85
    • 0029854007 scopus 로고    scopus 로고
    • Identification and characterization of yeast mutants that overcome an experimentally introduced block to splicing at the 3′ splice site
    • Lin J, Rossi JJ. 1996. Identification and characterization of yeast mutants that overcome an experimentally introduced block to splicing at the 3′ splice site. RNA 2:835-48
    • (1996) RNA , vol.2 , pp. 835-848
    • Lin, J.1    Rossi, J.J.2
  • 87
    • 0035798243 scopus 로고    scopus 로고
    • Structural basis for recognition of the intron branch site RNA by Splicing Factor 1
    • Liu Z, Luyten I, Bottomley MJ, Messias AC, Houngninou-Molango S, et al. 2001. Structural basis for recognition of the intron branch site RNA by Splicing Factor 1. Science 294:1098-102
    • (2001) Science , vol.294 , pp. 1098-1102
    • Liu, Z.1    Luyten, I.2    Bottomley, M.J.3    Messias, A.C.4    Houngninou-Molango, S.5
  • 88
    • 0032865541 scopus 로고    scopus 로고
    • Genomic-scale quantitative analysis of yeast pre-mRNA splicing: Implications for splice-site recognition
    • Lopez PJ, Séraphin B. 1999. Genomic-scale quantitative analysis of yeast pre-mRNA splicing: implications for splice-site recognition. RNA 5:1135-37
    • (1999) RNA , vol.5 , pp. 1135-1137
    • Lopez, P.J.1    Séraphin, B.2
  • 89
    • 0036009859 scopus 로고    scopus 로고
    • Defining a 5′ splice site by functional selection in the presence and absence of U1 snRNA 5′ end
    • Lund M, Kjems J. 2002. Defining a 5′ splice site by functional selection in the presence and absence of U1 snRNA 5′ end. RNA 8:166-79
    • (2002) RNA , vol.8 , pp. 166-179
    • Lund, M.1    Kjems, J.2
  • 90
    • 0035812381 scopus 로고    scopus 로고
    • Direct pKa measurement of the active-site cytosine in a genomic hepatitis delta virus ribozyme
    • Lupták A, Ferré-D'Amaré AR, Zhou K, Zilm KW, Doudna JA. 2001. Direct pKa measurement of the active-site cytosine in a genomic hepatitis delta virus ribozyme. J. Am. Chem. Soc. 123:8447-52
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 8447-8452
    • Lupták, A.1    Ferré-D'Amaré, A.R.2    Zhou, K.3    Zilm, K.W.4    Doudna, J.A.5
  • 91
    • 0032908071 scopus 로고    scopus 로고
    • Elevated levels of a U4/U6.U5 snRNP-associated protein, Spp381p, rescue a mutant defective in spliceosome maturation
    • Lybarger S, Beickman K, Brown V, Dembla-Rajpal N, Morey K, et al. 1999. Elevated levels of a U4/U6.U5 snRNP-associated protein, Spp381p, rescue a mutant defective in spliceosome maturation. Mol. Cell. Biol. 19:577-84
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 577-584
    • Lybarger, S.1    Beickman, K.2    Brown, V.3    Dembla-Rajpal, N.4    Morey, K.5
  • 92
    • 0028281593 scopus 로고
    • Extragenic suppressors of Saccharomyces cerevisiae prp4 mutations identify a negative regulator of PRP genes
    • Maddock JR, Weidenhammer EM, Adams CC, Lunz RL, Woolford JL Jr. 1994. Extragenic suppressors of Saccharomyces cerevisiae prp4 mutations identify a negative regulator of PRP genes. Genetics 136:833-47
    • (1994) Genetics , vol.136 , pp. 833-847
    • Maddock, J.R.1    Weidenhammer, E.M.2    Adams, C.C.3    Lunz, R.L.4    Woolford J.L., Jr.5
  • 93
    • 0028175201 scopus 로고
    • Randomization-selection analysis of snRNAs in vivo: Evidence for a tertiary interaction in the spliceosome
    • Madhani HD, Guthrie C. 1994. Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome. Genes Dev. 8:1071-86
    • (1994) Genes Dev. , vol.8 , pp. 1071-1086
    • Madhani, H.D.1    Guthrie, C.2
  • 94
    • 0028556367 scopus 로고
    • Dynamic RNA-RNA interactions in the spliceosome
    • Madhani HD, Guthrie C. 1994. Dynamic RNA-RNA interactions in the spliceosome. Annu. Rev. Genet. 28:1-26
    • (1994) Annu. Rev. Genet. , vol.28 , pp. 1-26
    • Madhani, H.D.1    Guthrie, C.2
  • 95
    • 0036500141 scopus 로고    scopus 로고
    • Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6.U5 trisnRNP formation and pre-mRNA splicing
    • Makarova OV, Makarov EM, Liu S, Vornlocher H-P, Lührmann R. 2002. Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6.U5 trisnRNP formation and pre-mRNA splicing. EMBO J. 21:1148-57
    • (2002) EMBO J. , vol.21 , pp. 1148-1157
    • Makarova, O.V.1    Makarov, E.M.2    Liu, S.3    Vornlocher, H.-P.4    Lührmann, R.5
  • 96
    • 0033634673 scopus 로고    scopus 로고
    • Functional recognition of the 5′ splice site by U4/U6.U5 tri-snRNP defines a novel ATP-dependent step in early splicesome assembly
    • Maroney PA, Romfo CM, Nilsen TW. 2000. Functional recognition of the 5′ splice site by U4/U6.U5 tri-snRNP defines a novel ATP-dependent step in early splicesome assembly. Mol. Cell 6:317-28
    • (2000) Mol. Cell , vol.6 , pp. 317-328
    • Maroney, P.A.1    Romfo, C.M.2    Nilsen, T.W.3
  • 97
    • 0037124096 scopus 로고    scopus 로고
    • Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome
    • Martin A, Schneider S, Schwer B. 2002. Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome. J. Biol. Chem. 277:17743-50
    • (2002) J. Biol. Chem. , vol.277 , pp. 17743-17750
    • Martin, A.1    Schneider, S.2    Schwer, B.3
  • 98
    • 0035878541 scopus 로고    scopus 로고
    • Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13)
    • McKie AB, McHale JC, Keen TJ, Tarttelin EE, Goliath R, et al. 2001. Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum. Mol. Genet. 10:1555-62
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1555-1562
    • McKie, A.B.1    McHale, J.C.2    Keen, T.J.3    Tarttelin, E.E.4    Goliath, R.5
  • 99
    • 0029959586 scopus 로고    scopus 로고
    • Interactions of the yeast U6 RNA with the pre-mRNA branch site
    • McPheeters DS. 1996. Interactions of the yeast U6 RNA with the pre-mRNA branch site. RNA 2:1110-23
    • (1996) RNA , vol.2 , pp. 1110-1123
    • McPheeters, D.S.1
  • 100
    • 0033576625 scopus 로고    scopus 로고
    • Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3′ splice site AG
    • Merendino L, Guth S, Bilbao D, Martinez C, Valcárcel J. 1999. Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3′ splice site AG. Nature 402:838-41
    • (1999) Nature , vol.402 , pp. 838-841
    • Merendino, L.1    Guth, S.2    Bilbao, D.3    Martinez, C.4    Valcárcel, J.5
  • 101
    • 0027215924 scopus 로고
    • A functional association between the 5′ and 3′ splice sites is established in the earliest prespliceosome complex (E) in mammals
    • Michaud S, Reed R. 1993. A functional association between the 5′ and 3′ splice sites is established in the earliest prespliceosome complex (E) in mammals. Genes Dev. 7:1008-20
    • (1993) Genes Dev. , vol.7 , pp. 1008-1020
    • Michaud, S.1    Reed, R.2
  • 102
    • 0029066770 scopus 로고
    • Structure and activities of group II introns
    • Michel F, Ferat J-L. 1995. Structure and activities of group II introns. Annu. Rev. Biochem. 64:435-61
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 435-461
    • Michel, F.1    Ferat, J.-L.2
  • 103
    • 0034712097 scopus 로고    scopus 로고
    • General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme
    • Nakano S, Chadalavada DM, Bevilacqua PC. 2000. General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme. Science 287:1493-97
    • (2000) Science , vol.287 , pp. 1493-1497
    • Nakano, S.1    Chadalavada, D.M.2    Bevilacqua, P.C.3
  • 105
    • 0029400769 scopus 로고
    • snRNA interactions at the 5′ and 3′ splice sites monitored by photoactivated crosslinking in yeast splicesomes
    • Newman AJ, Teigelkamp S, Beggs JD. 1995. snRNA interactions at the 5′ and 3′ splice sites monitored by photoactivated crosslinking in yeast splicesomes. RNA 1:968-80
    • (1995) RNA , vol.1 , pp. 968-980
    • Newman, A.J.1    Teigelkamp, S.2    Beggs, J.D.3
  • 106
    • 0034840125 scopus 로고    scopus 로고
    • The ATP requirement for U2 snRNP addition is linked to the pre-mRNA region 5′ to the branch site
    • Newnham CM, Query CC. 2001. The ATP requirement for U2 snRNP addition is linked to the pre-mRNA region 5′ to the branch site. RNA 7:1298-309
    • (2001) RNA , vol.7 , pp. 1298-1309
    • Newnham, C.M.1    Query, C.C.2
  • 107
    • 0002340095 scopus 로고    scopus 로고
    • RNA-RNA interactions in nuclear pre-mRNA splicing
    • ed. R. Simons, M. Grunberg-Manago. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press
    • Nilsen TW. 1998. RNA-RNA interactions in nuclear pre-mRNA splicing. In RNA Structure and Function, ed. R. Simons, M. Grunberg-Manago, pp. 279-307. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press
    • (1998) RNA Structure and Function , pp. 279-307
    • Nilsen, T.W.1
  • 108
    • 0029871680 scopus 로고    scopus 로고
    • Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations
    • Noble SM, Guthrie C. 1996. Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations. Genetics 143:67-80
    • (1996) Genetics , vol.143 , pp. 67-80
    • Noble, S.M.1    Guthrie, C.2
  • 109
    • 0030475009 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA
    • O'Day CL, Dalbadie-McFarland G, Abelson J. 1996. The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA. J. Biol. Chem. 271:33261-67
    • (1996) J. Biol. Chem. , vol.271 , pp. 33261-33267
    • O'Day, C.L.1    Dalbadie-McFarland, G.2    Abelson, J.3
  • 110
    • 0036118353 scopus 로고    scopus 로고
    • Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs
    • Ohi MD, Link AJ, Ren L, Jennings JL, McDonald WH, Gould K. 2002. Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol. Cell. Biol. 22:2011-24
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2011-2024
    • Ohi, M.D.1    Link, A.J.2    Ren, L.3    Jennings, J.L.4    McDonald, W.H.5    Gould, K.6
  • 111
    • 0009361523 scopus 로고
    • Splicing of adenovirus RNA in a cell-free transcription system
    • Padgett RA, Hardy SF, Sharp PA. 1983. Splicing of adenovirus RNA in a cell-free transcription system. Proc. Natl. Acad. Sci. USA 80:5230-34
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 5230-5234
    • Padgett, R.A.1    Hardy, S.F.2    Sharp, P.A.3
  • 112
    • 1842326159 scopus 로고    scopus 로고
    • The branchpoint residue is recognized during commitment complex formation before being bulged out of the U2 snRNA-pre-mRNA duplex
    • Pascolo E, Séraphin B. 1997. The branchpoint residue is recognized during commitment complex formation before being bulged out of the U2 snRNA-pre-mRNA duplex. Mol. Cell. Biol. 17:3469-76
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3469-3476
    • Pascolo, E.1    Séraphin, B.2
  • 114
    • 0033999317 scopus 로고    scopus 로고
    • Functional Cus1p is found with Hsh155p in a multiprotein splicing factor associated with U2 snRNA
    • Pauling MH, McPheeters DS, Ares M Jr. 2000. Functional Cus1p is found with Hsh155p in a multiprotein splicing factor associated with U2 snRNA. Mol. Cell. Biol. 20:2176-85
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2176-2185
    • Pauling, M.H.1    McPheeters, D.S.2    Ares M., Jr.3
  • 115
    • 0034948027 scopus 로고    scopus 로고
    • Recognition of RNA branch point sequences by the KH domain of splicing factor 1 (mammalian branch point binding protein) in a splicing factor complex
    • Peled-Zehavi H, Berglund A, Rosbash M, Frankel AD. 2001. Recognition of RNA branch point sequences by the KH domain of splicing factor 1 (mammalian branch point binding protein) in a splicing factor complex. Mol. Cell. Biol. 21:5232-41
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5232-5241
    • Peled-Zehavi, H.1    Berglund, A.2    Rosbash, M.3    Frankel, A.D.4
  • 116
    • 0343851620 scopus 로고    scopus 로고
    • ATP can be dispensable for prespliceosome formation in yeast
    • Perriman R, Ares M Jr. 2000. ATP can be dispensable for prespliceosome formation in yeast. Genes Dev. 14:97-107
    • (2000) Genes Dev. , vol.14 , pp. 97-107
    • Perriman, R.1    Ares M., Jr.2
  • 117
    • 0022997930 scopus 로고
    • Electrophoresis of ribonucleoproteins reveals an ordered assembly of yeast splicing complexes
    • Pikielny CW, Rymond BC, Rosbash M. 1986. Electrophoresis of ribonucleoproteins reveals an ordered assembly of yeast splicing complexes. Nature 324:341-45
    • (1986) Nature , vol.324 , pp. 341-345
    • Pikielny, C.W.1    Rymond, B.C.2    Rosbash, M.3
  • 119
    • 0033105003 scopus 로고    scopus 로고
    • Interaction of the U1 snRNP with nonconserved intronic sequences affects 5′ splice site selection
    • Puig O, Gottschalk A, Fabrizio P, Séraphin B. 1999. Interaction of the U1 snRNP with nonconserved intronic sequences affects 5′ splice site selection. Genes Dev. 13:569-80
    • (1999) Genes Dev. , vol.13 , pp. 569-580
    • Puig, O.1    Gottschalk, A.2    Fabrizio, P.3    Séraphin, B.4
  • 120
    • 0032488860 scopus 로고    scopus 로고
    • A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles
    • Raghunathan PL, Guthrie C. 1998. A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles. Science 279:857-60
    • (1998) Science , vol.279 , pp. 857-860
    • Raghunathan, P.L.1    Guthrie, C.2
  • 121
    • 0032537739 scopus 로고    scopus 로고
    • RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
    • Raghunathan PL, Guthrie C. 1998. RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr. Biol. 8:847-55
    • (1998) Curr. Biol. , vol.8 , pp. 847-855
    • Raghunathan, P.L.1    Guthrie, C.2
  • 122
    • 0031958545 scopus 로고    scopus 로고
    • Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1
    • Rain J-C, Rafi Z, Rhani Z, Legrain P, Krämer A. 1998. Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1. RNA 4:551-65
    • (1998) RNA , vol.4 , pp. 551-565
    • Rain, J.-C.1    Rafi, Z.2    Rhani, Z.3    Legrain, P.4    Krämer, A.5
  • 123
    • 0029933504 scopus 로고    scopus 로고
    • Initial splice-site recognition and pairing during pre-mRNA splicing
    • Reed R. 1996. Initial splice-site recognition and pairing during pre-mRNA splicing. Curr. Opin. Genet. Dev. 6:215-20
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 215-220
    • Reed, R.1
  • 124
    • 0029827836 scopus 로고    scopus 로고
    • The canonical GU dinucleotide at the 5′ splice site is recognized by p220 of the U5 snRNP within the spliceosome
    • Reyes JL, Kois P, Konforti B, Konarska MM. 1996. The canonical GU dinucleotide at the 5′ splice site is recognized by p220 of the U5 snRNP within the spliceosome. RNA 2:213-25
    • (1996) RNA , vol.2 , pp. 213-225
    • Reyes, J.L.1    Kois, P.2    Konforti, B.3    Konarska, M.M.4
  • 126
    • 0030808771 scopus 로고    scopus 로고
    • Both the polypyrimidine tract and the 3′ splice site function prior to the first step of splicing in fission yeast
    • Romfo CM, Wise JA. 1997. Both the polypyrimidine tract and the 3′ splice site function prior to the first step of splicing in fission yeast. Nucleic Acids Res. 25:4658-65
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4658-4665
    • Romfo, C.M.1    Wise, J.A.2
  • 127
    • 0025876808 scopus 로고
    • Who's on first? The U1snRNP-5′ splice site interaction and splicing
    • Rosbash M, Séraphin B. 1991. Who's on first? The U1snRNP-5′ splice site interaction and splicing. Trends Biochem. Sci. 16:187-90
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 187-190
    • Rosbash, M.1    Séraphin, B.2
  • 128
    • 0029312195 scopus 로고
    • The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing
    • Roy J, Kim K, Maddock JR, Anthony JG, Woolford JL Jr. 1995. The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing. RNA 1:375-90
    • (1995) RNA , vol.1 , pp. 375-390
    • Roy, J.1    Kim, K.2    Maddock, J.R.3    Anthony, J.G.4    Woolford J.L., Jr.5
  • 129
    • 0030841913 scopus 로고    scopus 로고
    • Dynamics of the U1 small nuclear ribonucleoprotein during yeast spliceosome assembly
    • Ruby SW. 1997. Dynamics of the U1 small nuclear ribonucleoprotein during yeast spliceosome assembly. J. Biol. Chem. 272:17333-41
    • (1997) J. Biol. Chem. , vol.272 , pp. 17333-17341
    • Ruby, S.W.1
  • 130
    • 0024291370 scopus 로고
    • An early hierarchic role of U1 small nuclear ribonucleoprotein in spliceosome assembly
    • Ruby SW, Abelson J. 1988. An early hierarchic role of U1 small nuclear ribonucleoprotein in spliceosome assembly. Science 242:1028-35
    • (1988) Science , vol.242 , pp. 1028-1035
    • Ruby, S.W.1    Abelson, J.2
  • 131
    • 0027428138 scopus 로고
    • Four yeast spliceosomal proteins (PRP5, PRP9, PRP11 and PRP21) interact to promote U2 snRNP binding to pre-mRNA
    • Ruby SW, Chang T-H, Abelson J. 1993. Four yeast spliceosomal proteins (PRP5, PRP9, PRP11 and PRP21) interact to promote U2 snRNP binding to pre-mRNA. Genes Dev. 7:1909-25
    • (1993) Genes Dev. , vol.7 , pp. 1909-1925
    • Ruby, S.W.1    Chang, T.-H.2    Abelson, J.3
  • 132
    • 0033730605 scopus 로고    scopus 로고
    • Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae
    • Russell CS, Ben-Yehuda S, Dix I, Kupiec M, Beggs JD. 2000. Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae. RNA 6:1565-72
    • (2000) RNA , vol.6 , pp. 1565-1572
    • Russell, C.S.1    Ben-Yehuda, S.2    Dix, I.3    Kupiec, M.4    Beggs, J.D.5
  • 133
    • 0345593813 scopus 로고    scopus 로고
    • Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly
    • Rutz B, Séraphin B. 1999. Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly. RNA 5:819-31
    • (1999) RNA , vol.5 , pp. 819-831
    • Rutz, B.1    Séraphin, B.2
  • 134
    • 0022343426 scopus 로고
    • Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing
    • Rymond BC, Rosbash M. 1985. Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing. Nature 317:735-37
    • (1985) Nature , vol.317 , pp. 735-737
    • Rymond, B.C.1    Rosbash, M.2
  • 135
    • 0026453396 scopus 로고
    • Evidence for a base-pairing interaction between U6 small nuclear RNA and 5′ splice site during the splicing reaction in yeast
    • Sawa H, Abelson J. 1992. Evidence for a base-pairing interaction between U6 small nuclear RNA and 5′ splice site during the splicing reaction in yeast. Proc. Natl. Acad. Sci. USA 89:11269-73
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11269-11273
    • Sawa, H.1    Abelson, J.2
  • 136
    • 0029902842 scopus 로고    scopus 로고
    • Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo
    • Schwer B, Shuman S. 1996. Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo. RNA 2:574-83
    • (1996) RNA , vol.2 , pp. 574-583
    • Schwer, B.1    Shuman, S.2
  • 137
    • 0024325159 scopus 로고
    • Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing
    • Séraphin B, Rosbash M. 1989. Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing. Cell 59:349-58
    • (1989) Cell , vol.59 , pp. 349-358
    • Séraphin, B.1    Rosbash, M.2
  • 138
    • 0025733098 scopus 로고
    • The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 RNA
    • Séraphin B, Rosbash M. 1991. The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 RNA. EMBO J. 10:1209-16
    • (1991) EMBO J. , vol.10 , pp. 1209-1216
    • Séraphin, B.1    Rosbash, M.2
  • 139
    • 0025906517 scopus 로고
    • Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs
    • Shannon KW, Guthrie C. 1991. Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs. Genes Dev. 5:773-85
    • (1991) Genes Dev. , vol.5 , pp. 773-785
    • Shannon, K.W.1    Guthrie, C.2
  • 140
    • 0034098296 scopus 로고    scopus 로고
    • Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal
    • Singh R, Banerjee H, Green MR. 2000. Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal. RNA 6:901-11
    • (2000) RNA , vol.6 , pp. 901-911
    • Singh, R.1    Banerjee, H.2    Green, M.R.3
  • 141
    • 0033034668 scopus 로고    scopus 로고
    • Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae
    • Spignola M, Grate L, Haussler D, Ares M. 1999. Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae. RNA 5:221-34
    • (1999) RNA , vol.5 , pp. 221-234
    • Spignola, M.1    Grate, L.2    Haussler, D.3    Ares, M.4
  • 142
    • 0032489021 scopus 로고    scopus 로고
    • Mechanical devices of the spliceosome: Motors, clocks, springs, and things
    • Staley JP, Guthrie C. 1998. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92:315-26
    • (1998) Cell , vol.92 , pp. 315-326
    • Staley, J.P.1    Guthrie, C.2
  • 143
    • 0033010430 scopus 로고    scopus 로고
    • An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p
    • Staley JP, Guthrie C. 1999. An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p. Mol. Cell 3:55-64
    • (1999) Mol. Cell , vol.3 , pp. 55-64
    • Staley, J.P.1    Guthrie, C.2
  • 145
    • 0030960198 scopus 로고    scopus 로고
    • Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
    • Tang J, Abovich N, Fleming ML, Séraphin B, Rosbash M. 1997. Identification and characterization of a yeast homolog of U1 snRNP-specific protein C. EMBO J. 16:4082-91
    • (1997) EMBO J. , vol.16 , pp. 4082-4091
    • Tang, J.1    Abovich, N.2    Fleming, M.L.3    Séraphin, B.4    Rosbash, M.5
  • 146
    • 0034857262 scopus 로고    scopus 로고
    • DExD/H box RNA helicases: From generic motors to specific dissociation functions
    • Tanner NK, Linder P. 2001. DExD/H box RNA helicases: from generic motors to specific dissociation functions. Mol. Cell 8:251-62
    • (2001) Mol. Cell , vol.8 , pp. 251-262
    • Tanner, N.K.1    Linder, P.2
  • 147
    • 0027491331 scopus 로고
    • Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA
    • Tarn W-Y, Lee K-R, Cheng S-C. 1993. Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA. Proc. Natl. Acad. Sci. USA 90:10821-25
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10821-10825
    • Tarn, W.-Y.1    Lee, K.-R.2    Cheng, S.-C.3
  • 148
    • 0028158655 scopus 로고
    • The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNA
    • Teigelkamp S, McGarvey M, Plumpton M, Beggs JD. 1994. The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNA. EMBO J. 13:888-97
    • (1994) EMBO J. , vol.13 , pp. 888-897
    • Teigelkamp, S.1    McGarvey, M.2    Plumpton, M.3    Beggs, J.D.4
  • 149
    • 0029397324 scopus 로고
    • The second catalytic step of splicing
    • Umen JG, Guthrie C. 1995. The second catalytic step of splicing. RNA 1:869-85
    • (1995) RNA , vol.1 , pp. 869-885
    • Umen, J.G.1    Guthrie, C.2
  • 150
    • 0033962271 scopus 로고    scopus 로고
    • A tertiary interaction detected in a human U2/U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast
    • Valadkhan S, Manley JL. 2000. A tertiary interaction detected in a human U2/U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast. RNA 6:206-19
    • (2000) RNA , vol.6 , pp. 206-219
    • Valadkhan, S.1    Manley, J.L.2
  • 151
    • 0035909314 scopus 로고    scopus 로고
    • Splicing-related catalysis by protein-free snRNAs
    • Valadkhan S, Manley JL. 2001. Splicing-related catalysis by protein-free snRNAs. Nature 413:701-7
    • (2001) Nature , vol.413 , pp. 701-707
    • Valadkhan, S.1    Manley, J.L.2
  • 152
    • 0035053295 scopus 로고    scopus 로고
    • Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae
    • van Nues RW, Beggs JD. 2001. Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157:1451-67
    • (2001) Genetics , vol.157 , pp. 1451-1467
    • Van Nues, R.W.1    Beggs, J.D.2
  • 153
    • 0032736975 scopus 로고    scopus 로고
    • Multiple functions of Saccharomyces cerevisiae splicing protein Prp24 in U6 RNA structural rearrangements
    • Vidaver RM, Fortner DM, Loos-Austin LS, Brow DA. 1999. Multiple functions of Saccharomyces cerevisiae splicing protein Prp24 in U6 RNA structural rearrangements. Genetics 153:1205-18
    • (1999) Genetics , vol.153 , pp. 1205-1218
    • Vidaver, R.M.1    Fortner, D.M.2    Loos-Austin, L.S.3    Brow, D.A.4
  • 154
    • 17944379537 scopus 로고    scopus 로고
    • A human homolog of yeast pre-mRNA splicing gene, PRP31, underlies autosomal dominant retinitis pigmentosa on chromosome 19q13.4 (RP11)
    • Vithana EN, Abu-Safieh L, Allen MJ, Carey A, Papaioannou M, et al. 2001. A human homolog of yeast pre-mRNA splicing gene, PRP31, underlies autosomal dominant retinitis pigmentosa on chromosome 19q13.4 (RP11). Mol. Cell 8:375-81
    • (2001) Mol. Cell , vol.8 , pp. 375-381
    • Vithana, E.N.1    Abu-Safieh, L.2    Allen, M.J.3    Carey, A.4    Papaioannou, M.5
  • 155
    • 0032523934 scopus 로고    scopus 로고
    • Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis
    • Wang C, Chua K, Seghezzi W, Lees E, Gozani O, Reed R. 1998. Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis. Genes Dev. 12:1409-14
    • (1998) Genes Dev. , vol.12 , pp. 1409-1414
    • Wang, C.1    Chua, K.2    Seghezzi, W.3    Lees, E.4    Gozani, O.5    Reed, R.6
  • 156
    • 0026670431 scopus 로고
    • Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing
    • Wassarman DA, Steitz JA. 1992. Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing. Science 257:1918-25
    • (1992) Science , vol.257 , pp. 1918-1925
    • Wassarman, D.A.1    Steitz, J.A.2
  • 157
    • 0030927321 scopus 로고    scopus 로고
    • Prp31p promotes the association of the U4/U6.U5 trisnRNP with pre-spliceosomes to form spliceosomes in Saccharomyces cerevisae
    • Weidenhammer EM, Ruiz-Noriega M, Woolford JL Jr. 1997. Prp31p promotes the association of the U4/U6.U5 trisnRNP with pre-spliceosomes to form spliceosomes in Saccharomyces cerevisae. Mol. Cell. Biol. 17:3580-88
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3580-3588
    • Weidenhammer, E.M.1    Ruiz-Noriega, M.2    Woolford J.L., Jr.3
  • 158
    • 0030463475 scopus 로고    scopus 로고
    • In vitro studies of the Prp9 · Prp11 · Prp21 complex indicate a pathway for U2 small nuclear ribonucleoprotein activation
    • Weist DK, O'Day CL, Abelson J. 1996. In vitro studies of the Prp9 · Prp11 · Prp21 complex indicate a pathway for U2 small nuclear ribonucleoprotein activation. J. Biol. Chem. 271:33268-76
    • (1996) J. Biol. Chem. , vol.271 , pp. 33268-33276
    • Weist, D.K.1    O'Day, C.L.2    Abelson, J.3
  • 159
    • 0030024636 scopus 로고    scopus 로고
    • CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145
    • Wells SE, Neville M, Haynes M, Wang J, Igel H, Ares M Jr. 1996. CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145. Genes Dev. 10:220-32
    • (1996) Genes Dev. , vol.10 , pp. 220-232
    • Wells, S.E.1    Neville, M.2    Haynes, M.3    Wang, J.4    Igel, H.5    Ares M., Jr.6
  • 160
    • 0029890769 scopus 로고    scopus 로고
    • The small subunit of the splicing factor U2AF is conserved in fission yeast
    • Wentz-Hunter K, Potashkin J. 1996. The small subunit of the splicing factor U2AF is conserved in fission yeast. Nucleic Acids Res. 24:1849-54
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1849-1854
    • Wentz-Hunter, K.1    Potashkin, J.2
  • 161
    • 0035882161 scopus 로고    scopus 로고
    • A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site
    • Will CL, Schneider C, MacMillan AM, Katopodis NF, Neubauer G, et al. 2001. A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. EMBO J. 20:4536-46
    • (2001) EMBO J. , vol.20 , pp. 4536-4546
    • Will, C.L.1    Schneider, C.2    MacMillan, A.M.3    Katopodis, N.F.4    Neubauer, G.5
  • 163
    • 0033576626 scopus 로고    scopus 로고
    • Functional recognition of the 3′ splice site AG by the splicing factor U2AF35
    • Wu S, Romfo CM, Nilsen TW, Green MR. 1999. Functional recognition of the 3′ splice site AG by the splicing factor U2AF35. Nature 402:832-35
    • (1999) Nature , vol.402 , pp. 832-835
    • Wu, S.1    Romfo, C.M.2    Nilsen, T.W.3    Green, M.R.4
  • 164
    • 0027059033 scopus 로고
    • Site-specific cross-linking of mammalian U5 snRNP to the 5′ splice site before the first step of pre-mRNA splicing
    • Wyatt JR, Sontheimer EJ, Steitz JA. 1992. Site-specific cross-linking of mammalian U5 snRNP to the 5′ splice site before the first step of pre-mRNA splicing. Genes Dev. 6:2542-53
    • (1992) Genes Dev. , vol.6 , pp. 2542-2553
    • Wyatt, J.R.1    Sontheimer, E.J.2    Steitz, J.A.3
  • 165
    • 0032525135 scopus 로고    scopus 로고
    • Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation
    • Xie J, Beickman K, Otte E, Rymond BC. 1998. Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation. EMBO J. 17:2938-46
    • (1998) EMBO J. , vol.17 , pp. 2938-2946
    • Xie, J.1    Beickman, K.2    Otte, E.3    Rymond, B.C.4
  • 166
    • 0031922271 scopus 로고    scopus 로고
    • Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggest functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing
    • Xu D, Field DJ, Tang S-J, Moris A, Bobechko BO, Friesen JD. 1998. Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggest functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing. Mol. Cell. Biol. 18:2055-66
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2055-2066
    • Xu, D.1    Field, D.J.2    Tang, S.-J.3    Moris, A.4    Bobechko, B.O.5    Friesen, J.D.6
  • 167
    • 0035144581 scopus 로고    scopus 로고
    • Splicing factor Slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosome
    • Xu D, Friesen JD. 2001. Splicing factor Slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosome. Mol. Cell. Biol. 21:1011-23
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1011-1023
    • Xu, D.1    Friesen, J.D.2
  • 168
    • 0029888811 scopus 로고    scopus 로고
    • An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing
    • Xu D, Nouraini S, Field D, Tang S-J, Friesen JD. 1996. An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing. Nature 381:709-13
    • (1996) Nature , vol.381 , pp. 709-713
    • Xu, D.1    Nouraini, S.2    Field, D.3    Tang, S.-J.4    Friesen, J.D.5
  • 169
    • 0031865048 scopus 로고    scopus 로고
    • Cus2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif
    • Yan D, Perriman R, Igel H, Howe KJ, Neville M, Ares M Jr. 1998. Cus2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif. Mol. Cell. Biol. 18:5000-9
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5000-5009
    • Yan, D.1    Perriman, R.2    Igel, H.3    Howe, K.J.4    Neville, M.5    Ares M., Jr.6
  • 170
    • 0025941556 scopus 로고
    • U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction
    • Yean S-L, Lin R-J. 1991. U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction. Mol. Cell. Biol. 11:5571-77
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5571-5577
    • Yean, S.-L.1    Lin, R.-J.2
  • 171
    • 0030338611 scopus 로고    scopus 로고
    • Analysis of small nuclear RNAs in a precatalytic spliceosome
    • Yean S-L, Lin R-J. 1996. Analysis of small nuclear RNAs in a precatalytic spliceosome. Gene Express. 5:301-13
    • (1996) Gene Express. , vol.5 , pp. 301-313
    • Yean, S.-L.1    Lin, R.-J.2
  • 172
    • 0034649666 scopus 로고    scopus 로고
    • Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome
    • Yean S-L, Wuenschell G, Termini J, Lin R-J. 2000. Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. Nature 408:881-84
    • (2000) Nature , vol.408 , pp. 881-884
    • Yean, S.-L.1    Wuenschell, G.2    Termini, J.3    Lin, R.-J.4
  • 173
    • 0024408832 scopus 로고
    • Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor
    • Zamore PD, Green MR. 1989. Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc. Natl. Acad. Sci. USA 86:9243-47
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9243-9247
    • Zamore, P.D.1    Green, M.R.2
  • 174
    • 0028349788 scopus 로고
    • Mutations in an essential U2 small nuclear RNA structure cause cold-sensitive U2 small nuclear ribonucleoprotein function by favoring competing alternative U2 RNA structures
    • Zavanelli MI, Britton JS, Igel AH, Ares M Jr. 1994. Mutations in an essential U2 small nuclear RNA structure cause cold-sensitive U2 small nuclear ribonucleoprotein function by favoring competing alternative U2 RNA structures. Mol. Cell. Biol. 14:1689-97
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1689-1697
    • Zavanelli, M.I.1    Britton, J.S.2    Igel, A.H.3    Ares M., Jr.4
  • 175
    • 0035106688 scopus 로고    scopus 로고
    • A biochemical function for the Sm complex
    • Zhang D, Abovich N, Rosbash M. 2001. A biochemical function for the Sm complex. Mol. Cell 7:319-29
    • (2001) Mol. Cell , vol.7 , pp. 319-329
    • Zhang, D.1    Abovich, N.2    Rosbash, M.3
  • 176
    • 0033106323 scopus 로고    scopus 로고
    • Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex
    • Zhang D, Rosbash M. 1999. Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex. Genes Dev. 13:581-92
    • (1999) Genes Dev. , vol.13 , pp. 581-592
    • Zhang, D.1    Rosbash, M.2
  • 177
    • 0035187881 scopus 로고    scopus 로고
    • Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56
    • Zhang M, Green MR. 2001. Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56. Genes Dev. 15:30-35
    • (2001) Genes Dev. , vol.15 , pp. 30-35
    • Zhang, M.1    Green, M.R.2
  • 178
    • 0033576591 scopus 로고    scopus 로고
    • Both subunits of U2AF recognize the 3′ splice site in Caenorhabditis elegans
    • Zorio DAR, Blumenthal T. 1999. Both subunits of U2AF recognize the 3′ splice site in Caenorhabditis elegans. Nature 402:835-38
    • (1999) Nature , vol.402 , pp. 835-838
    • Zorio, D.A.R.1    Blumenthal, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.