-
1
-
-
58849131828
-
Cancer and the tumor microenvironment: A review of an essential relationship
-
Mbeunkui F and Johann DJ: Cancer and the tumor microenvironment: a review of an essential relationship. Cancer Chemother Pharmacol 63: 571-582, 2009.
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 571-582
-
-
Mbeunkui, F.1
Johann, D.J.2
-
2
-
-
33749240527
-
The tumor microenvironment in the post-PAGET era
-
DOI 10.1016/j.canlet.2005.12.005, PII S0304383505010566
-
Witz IP and Levy-Nissenbaum O: The tumor microenvironment in the post-PAGET era. Cancer Lett 242: 1-10, 2006. (Pubitemid 44485302)
-
(2006)
Cancer Letters
, vol.242
, Issue.1
, pp. 1-10
-
-
Witz, I.P.1
Levy-Nissenbaum, O.2
-
3
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
DOI 10.1016/S0140-6736(00)04046-0
-
Balkwill F and Mantovani A: Inflammation and cancer: back to virchow? Lancet 357: 539-545, 2001. (Pubitemid 32173595)
-
(2001)
Lancet
, vol.357
, Issue.9255
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
4
-
-
4544322522
-
Inflammatory exposure and historical changes in human life-spans
-
DOI 10.1126/science.1092556
-
Finch CE and Crimmins EM: Inflammatory exposure and historical changes in human life-spans. Science 305: 1736-1739, 2004. (Pubitemid 39249633)
-
(2004)
Science
, vol.305
, Issue.5691
, pp. 1736-1739
-
-
Finch, C.E.1
Crimmins, E.M.2
-
6
-
-
17644394616
-
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
-
DOI 10.1016/j.ccr.2005.02.013
-
Balkwill F, Charles KA and Mantovani A: Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7: 211-217, 2005. (Pubitemid 40568680)
-
(2005)
Cancer Cell
, vol.7
, Issue.3
, pp. 211-217
-
-
Balkwill, F.1
Charles, K.A.2
Mantovani, A.3
-
7
-
-
3042788940
-
COX-2 inhibition and colorectal cancer
-
DOI 10.1016/j.seminoncol.2004.03.041, PII S0093775404001903
-
Koehne CH and Dubois RN: COX-2 inhibition and colorectal cancer. Semin Oncol 31: 12-21, 2004. (Pubitemid 38879410)
-
(2004)
Seminars in Oncology
, vol.31
, Issue.SUPPL. 7
, pp. 12-21
-
-
Koehne, C.-H.1
Dubois, R.N.2
-
8
-
-
34248157118
-
Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies
-
DOI 10.1016/S0140-6736(07)60747-8, PII S0140673607607478
-
Flossmann E and Rothwell PM: Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies. Lancet 369: 1603-1613, 2007. (Pubitemid 46710123)
-
(2007)
Lancet
, vol.369
, Issue.9573
, pp. 1603-1613
-
-
Flossmann, E.1
Rothwell, P.M.2
-
9
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J and Thun MJ: Cancer statistics, 2009. CA Cancer J Clin 59: 225-249, 2009.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
10
-
-
1642544603
-
Focus on hepatocellular carcinoma
-
DOI 10.1016/S1535-6108(04)00058-3, PII S1535610804000583
-
Bruix J, Boix L, Sala M and Llovet JM: Focus on hepatocellular carcinoma. Cancer Cell 5: 215-219, 2004. (Pubitemid 38402113)
-
(2004)
Cancer Cell
, vol.5
, Issue.3
, pp. 215-219
-
-
Bruix, J.1
Boix, L.2
Sala, M.3
Llovet, J.M.4
-
11
-
-
67449094451
-
Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma
-
Amann T, Bataille F, Spruss T, Muhlbauer M, Gabele E, Scholmerich J, Kiefer P, Bosserhoff AK and Hellerbrand C: Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma. Cancer Sci 100: 646-653, 2009.
-
(2009)
Cancer Sci
, vol.100
, pp. 646-653
-
-
Amann, T.1
Bataille, F.2
Spruss, T.3
Muhlbauer, M.4
Gabele, E.5
Scholmerich, J.6
Kiefer, P.7
Bosserhoff, A.K.8
Hellerbrand, C.9
-
12
-
-
78649681584
-
The 5th International Conference on Tumor Microenvironment: Progression, Therapy and Prevention Versailles, France, October 20-24, 2009: conference summary
-
Mohla S and Witz IP: The 5th International Conference on Tumor Microenvironment: Progression, Therapy and Prevention Versailles, France, October 20-24, 2009: conference summary. Cancer Microenviron 3: 1-5, 2010.
-
(2010)
Cancer Microenviron
, vol.3
, pp. 1-5
-
-
Mohla, S.1
Witz, I.P.2
-
13
-
-
53449094862
-
Stromal myo-fibroblasts are drivers of invasive cancer growth
-
De Wever O, Demetter P, Mareel M and Bracke M: Stromal myo-fibroblasts are drivers of invasive cancer growth. Int J Cancer 123: 2229-2238, 2008.
-
(2008)
Int J Cancer
, vol.123
, pp. 2229-2238
-
-
De Wever, O.1
Demetter, P.2
Mareel, M.3
Bracke, M.4
-
14
-
-
77951233373
-
Cancer associated fibroblasts (CAFs) in tumor microenvironment
-
Xing F, Saidou J and Watabe K: Cancer associated fibroblasts (CAFs) in tumor microenvironment. Front Biosci 15: 166-179, 2010.
-
(2010)
Front Biosci
, vol.15
, pp. 166-179
-
-
Xing, F.1
Saidou, J.2
Watabe, K.3
-
15
-
-
5044234897
-
Hepatocellular carcinoma: Role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis
-
Anzola M: Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis. J Viral Hepat 11: 383-393, 2004.
-
(2004)
J Viral Hepat
, vol.11
, pp. 383-393
-
-
Anzola, M.1
-
16
-
-
0032579547
-
A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma
-
DOI 10.1002/(SICI)1097-0215(19980130)75:3<347::AID-IJC4>3.0.CO;2-2
-
Donato F, Boffetta P and Puoti M: A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma. Int J Cancer 75: 347-354, 1998. (Pubitemid 28100034)
-
(1998)
International Journal of Cancer
, vol.75
, Issue.3
, pp. 347-354
-
-
Donato, F.1
Boffetta, P.2
Puoti, M.3
-
17
-
-
0032145740
-
Impact of HBV, HCV and GBV-C/HGV on hepatocellular carcinomas in Europe: Results of a European concerted action
-
DOI 10.1016/S0168-8278(98)80001-9
-
Brechot C, Jaffredo F, Lagorce D, Gerken G, Meyer zum Buschenfelde K, Papakonstontinou A, Hadziyannis S, Romeo R, Colombo M, Rodes J, Bruix J, Williams R and Naoumov N: Impact of HBV, HCV and GBV-C/HGV on hepatocellular carcinomas in Europe: results of a European concerted action. J Hepatol 29: 173-183, 1998. (Pubitemid 28352801)
-
(1998)
Journal of Hepatology
, vol.29
, Issue.2
, pp. 173-183
-
-
Brechot, C.1
Jaffredo, F.2
Lagorce, D.3
Gerken, G.4
Zum, B.K.M.5
Papakonstontinou, A.6
Hadziyannis, S.7
Romeo, R.8
Colombo, M.9
Rodes, J.10
Bruix, J.11
Williams, R.12
Naoumov, N.13
-
19
-
-
0031658280
-
A case-control study of hepatitis B and C virus infection as risk factors for hepatocellular carcinoma in Henan, China
-
DOI 10.1093/ije/27.4.574
-
Zhang JY, Dai M, Wang X, Lu WQ, Li DS, Zhang MX, Wang KJ, Dai LP, Han SG, Zhou YF and Zhuang H: A case-control study of hepatitis B and C virus infection as risk factors for hepatocellular carcinoma in Henan, China. Int J Epidemiol 27: 574-578, 1998. (Pubitemid 28431497)
-
(1998)
International Journal of Epidemiology
, vol.27
, Issue.4
, pp. 574-578
-
-
Zhang, J.-Y.1
Dai, M.2
Wang, X.3
Lu, W.-Q.4
Li, D.-S.5
Zhang, M.-X.6
Wang, K.-J.7
Dai, L.-P.8
Han, S.-G.9
Zhou, Y.-F.10
Zhuang, H.11
-
20
-
-
33846322772
-
Mutual confounding and interactive effects between hepatitis C and hepatitis B viral infections in hepatocellular carcinogenesis: A population-based case-control study in Taiwan
-
Sun CA, Farzadegan H, You SL, Lu SN, Wu MH, Wolfe L, Hardy W, Huang GT, Yang PM, Lee H and Chen CJ: Mutual confounding and interactive effects between hepatitis C and hepatitis B viral infections in hepatocellular carcinogenesis: a population-based case-control study in Taiwan. Cancer Epidemiol Biomarkers Prev 5: 173-178, 1996.
-
(1996)
Cancer Epidemiol Biomarkers Prev
, vol.5
, pp. 173-178
-
-
Sun, C.A.1
Farzadegan, H.2
You, S.L.3
Lu, S.N.4
Wu, M.H.5
Wolfe, L.6
Hardy, W.7
Huang, G.T.8
Yang, P.M.9
Lee, H.10
Chen, C.J.11
-
21
-
-
0030823524
-
Effect of hepatitis C and B virus infection on risk of hepatocellular carcinoma: A prospective study
-
Tsai JF, Jeng JE, Ho MS, Chang WY, Hsieh MY, Lin ZY and Tsai JH: Effect of hepatitis C and B virus infection on risk of hepatocellular carcinoma: a prospective study. Br J Cancer 76: 968-974, 2003.
-
(2003)
Br J Cancer
, vol.76
, pp. 968-974
-
-
Tsai, J.F.1
Jeng, J.E.2
Ho, M.S.3
Chang, W.Y.4
Hsieh, M.Y.5
Lin, Z.Y.6
Tsai, J.H.7
-
22
-
-
77950346282
-
Immunity, inflammation, and cancer
-
Grivennikov SI, Greten FR and Karin M: Immunity, inflammation, and cancer. Cell 140: 883-899, 2010.
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
23
-
-
0036271116
-
Viral determinants and host immune responses in the pathogenesis of HBV infection
-
Rapicetta M, Ferrari C and Levrero M: Viral determinants and host immune responses in the pathogenesis of HBV infection. J Med Virol 67: 454-457, 2002.
-
(2002)
J Med Virol
, vol.67
, pp. 454-457
-
-
Rapicetta, M.1
Ferrari, C.2
Levrero, M.3
-
24
-
-
0034678409
-
Intrahepatic T cells in hepatitis B: Viral control versus liver cell injury
-
Rehermann B: Intrahepatic T cells in hepatitis B: viral control versus liver cell injury. J Exp Med 191: 1263-1268, 2000.
-
(2000)
J Exp Med
, vol.191
, pp. 1263-1268
-
-
Rehermann, B.1
-
25
-
-
0033617583
-
Viral clearance without destruction of infected cells during acute HBV infection
-
DOI 10.1126/science.284.5415.825
-
Guidotti LG, Rochford R, Chung J, Shapiro M, Purcell R and Chisari FV: Viral clearance without destruction of infected cells during acute HBV infection. Science 284: 825-829, 1999. (Pubitemid 29291352)
-
(1999)
Science
, vol.284
, Issue.5415
, pp. 825-829
-
-
Guidotti, L.G.1
Rochford, R.2
Chung, J.3
Shapiro, M.4
Purcell, R.5
Chisari, F.V.6
-
26
-
-
0035905411
-
Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes
-
DOI 10.1084/jem.194.12.1755
-
Kakimi K, Lane TE, Wieland S, Asensio VC, Campbell IL, Chisari FV and Guidotti LG: Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes. J Exp Med 194: 1755-1766, 2001. (Pubitemid 34028655)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.12
, pp. 1755-1766
-
-
Kakimi, K.1
Lane, T.E.2
Wieland, S.3
Asensio, V.C.4
Campbell, I.L.5
Chisari, F.V.6
Guidotti, L.G.7
-
27
-
-
0036322490
-
Hepatocarcinogenesis in hepatitis viral infection: Lessons from transgenic mouse studies
-
Koike K: Hepatocarcinogenesis in hepatitis viral infection: lessons from transgenic mouse studies. J Gastroenterol 37: 55-64, 2002.
-
(2002)
J Gastroenterol
, vol.37
, pp. 55-64
-
-
Koike, K.1
-
28
-
-
0035180320
-
Immunopathogenesis of hepatitis C virus infection
-
DOI 10.1046/j.1440-1711.2001.01036.x
-
Freeman AJ, Marinos G, Ffrench RA and Lloyd AR: Immunopathogenesis of hepatitis C virus infection. Immunol Cell Biol 79: 515-536, 2001. (Pubitemid 33070441)
-
(2001)
Immunology and Cell Biology
, vol.79
, Issue.6
, pp. 515-536
-
-
Freeman, A.J.1
Marinos, G.2
Ffrench, R.A.3
Lloyd, A.R.4
-
29
-
-
0034518533
-
Cellular immune response in HCV infection
-
DOI 10.1007/s005350070001
-
Nakamura I and Imawari M: Cellular immune response in HCV infection. J Gastroenterol 35: 881-889, 2000. (Pubitemid 32042381)
-
(2000)
Journal of Gastroenterology
, vol.35
, Issue.12
, pp. 881-889
-
-
Nakamura, I.1
Imawari, M.2
-
30
-
-
19144365016
-
Effect of immune globulin on the prevention of experimental hepatitis C virus infection
-
Krawczynski K, Alter MJ, Tankersley DL, Beach M, Robertson BH, Lambert S, Kuo G, Spelbring JE, Meeks E, Sinha S and Carson DA: Effect of immune globulin on the prevention of experimental hepatitis C virus infection. J Infect Dis 173: 822-828, 1996. (Pubitemid 26176003)
-
(1996)
Journal of Infectious Diseases
, vol.173
, Issue.4
, pp. 822-828
-
-
Krawczynski, K.1
Alter, M.J.2
Tankersley, D.L.3
Beach, M.4
Robertson, B.H.5
Lambert, S.6
Kuo, G.7
Spelbring, J.E.8
Meeks, E.9
Sinha, S.10
Carson, D.A.11
-
31
-
-
0033056992
-
Hepatitis C viral quasispecies
-
DOI 10.1046/j.1365-2893.1999.t01-1-6120131.x
-
Gomez J, Martell M, Quer J, Cabot B and Esteban JI: Hepatitis C viral quasispecies. J Viral Hepat 6: 3-16, 1999. (Pubitemid 29077621)
-
(1999)
Journal of Viral Hepatitis
, vol.6
, Issue.1
, pp. 3-16
-
-
Gomez, J.1
Martell, M.2
Quer, J.3
Cabot, B.4
Esteban, J.I.5
-
32
-
-
0032823995
-
Natural and iatrogenic variation in hepatitis B virus
-
DOI 10.1002/(SICI)1099-1654(199907/09)9:3<183::AID-RMV248>3.0.CO;2- P
-
Ngui SL, Hallet R and Teo CG: Natural and iatrogenic variation in hepatitis B virus. Rev Med Virol 9: 183-209, 1999. (Pubitemid 29410507)
-
(1999)
Reviews in Medical Virology
, vol.9
, Issue.3
, pp. 183-209
-
-
Ngui, S.L.1
Hallet, R.2
Teo, C.G.3
-
33
-
-
0028360076
-
Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
-
DOI 10.1038/369407a0
-
Bertoletti A, Sette A, Chisari FV, Penna A, Levrero M, De Carli M, Fiaccadori F and Ferrari C: Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells. Nature 369: 407-410, 1994. (Pubitemid 24184055)
-
(1994)
Nature
, vol.369
, Issue.6479
, pp. 407-410
-
-
Bertoletti, A.1
Sette, A.2
Chisari, F.V.3
Penna, A.4
Levrero, M.5
De Carli, M.6
Fiaccadori, F.7
Ferrari, C.8
-
34
-
-
0030914290
-
Understanding the mechanisms of sustained signaling and T cell activation
-
Lanzavecchia A: Understanding the mechanisms of sustained signaling and T cell activation. J Exp Med 185: 1717-1719, 1997.
-
(1997)
J Exp Med
, vol.185
, pp. 1717-1719
-
-
Lanzavecchia, A.1
-
35
-
-
0027298445
-
Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells
-
DOI 10.1038/363156a0
-
Sloan-Lancaster J, Evavold BD and Allen PM: Induction of T-cell anergy by altered T-cell-receptor ligand on live antigenpresenting cells. Nature 363: 156-159, 1993. (Pubitemid 23147012)
-
(1993)
Nature
, vol.363
, Issue.6425
, pp. 156-159
-
-
Sloan-Lancaster, J.1
Evavold, B.D.2
Allen, P.M.3
-
36
-
-
0031872341
-
Immune pathogenesis of hepatocellular carcinoma
-
DOI 10.1084/jem.188.2.341
-
Nakamoto Y, Guidotti LG, Kuhlen CV, Fowler P and Chisari FV: Immune pathogenesis of hepatocellular carcinoma. J Exp Med 188: 341-350, 1998. (Pubitemid 28357762)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.2
, pp. 341-350
-
-
Nakamoto, Y.1
Guidotti, L.G.2
Kuhlen, C.V.3
Fowler, P.4
Chisari, F.V.5
-
37
-
-
32944474237
-
Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
-
DOI 10.1016/j.cell.2006.02.016, PII S0092867406001917
-
Karin M, Lawrence T and Nizet V: Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 124: 823-835, 2006. (Pubitemid 43261455)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 823-835
-
-
Karin, M.1
Lawrence, T.2
Nizet, V.3
-
39
-
-
0037422535
-
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation
-
DOI 10.1073/pnas.0237083100
-
Hofseth LJ, Saito S, Hussain SP, Espey MG, Miranda KM, Araki Y, Jhappan C, Higashimoto Y, He P, Linke SP, Quezado MM, Zurer I, Rotter V, Wink DA, Appella E and Harris CC: Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc Natl Acad Sci USA 100: 143-148, 2003. (Pubitemid 36078042)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.1
, pp. 143-148
-
-
Hofseth, L.J.1
Saito, S.2
Perwez, H.S.3
Espey, M.G.4
Miranda, K.M.5
Araki, Y.6
Jhappan, C.7
Higashimoto, Y.8
He, P.9
Linke, S.P.10
Quezado, M.M.11
Zurer, I.12
Rotter, V.13
Wink, D.A.14
Appella, E.15
Harris, C.C.16
-
40
-
-
0028567172
-
Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma
-
Hagen TM, Huang S, Curnutte J, Fowler P, Martinez V, Wehr CM, Ames BN and Chisari FV: Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. Proc Natl Acad Sci USA 91: 12808-12812, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12808-12812
-
-
Hagen, T.M.1
Huang, S.2
Curnutte, J.3
Fowler, P.4
Martinez, V.5
Wehr, C.M.6
Ames, B.N.7
Chisari, F.V.8
-
41
-
-
0042091978
-
Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles
-
DOI 10.1128/MCB.23.15.5282-5292.2003
-
Forgues M, Difilippantonio MJ, Linke SP, Ried T, Nagashima K, Feden J, Valerie K, Fukasawa K and Wang XW: Involvement of Crm1 in HBx-induced aberrant centriole replication and abnormal mitotic spindles. Mol Cell Biol 23: 5282-5292, 2003. (Pubitemid 36950883)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.15
, pp. 5282-5292
-
-
Forgues, M.1
Difilippantonio, M.J.2
Linke, S.P.3
Ried, T.4
Nagashima, K.5
Feden, J.6
Valerie, K.7
Fukasawa, K.8
Wang, X.W.9
-
42
-
-
0035804226
-
Activated ras oncogene collaborates with HBx gene of hepatitis B virus to transform cells by suppressing HBx-mediated apoptosis
-
DOI 10.1038/sj.onc.1203840
-
Kim YC, Song KS, Yoon G, Nam MJ and Ryu WS: Activated ras oncogene collaborates with HBx gene of hepatitis B virus to transform cells by suppressing HBx-mediated apoptosis. Oncogene 20: 16-23, 2001. (Pubitemid 32142334)
-
(2001)
Oncogene
, vol.20
, Issue.1
, pp. 16-23
-
-
Kim, Y.C.1
Song, K.-S.2
Yoon, G.3
Nam, M.-J.4
Ryu, W.-S.5
-
43
-
-
0036717295
-
Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation
-
DOI 10.1084/jem.20012127
-
Yoshida T, Hanada T, Tokuhisa T, Kosai K, Sata M, Kohara M and Yoshimura A: Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation. J Exp Med 196: 641-653, 2002. (Pubitemid 35024442)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.5
, pp. 641-653
-
-
Yoshida, T.1
Hanada, T.2
Tokuhisa, T.3
Kosai, K.-I.4
Sata, M.5
Kohara, M.6
Yoshimura, A.7
-
44
-
-
23144449790
-
Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication
-
DOI 10.1038/ncb1282
-
Wang W, Budhu A, Forgues M and Wang XW: Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication. Nat Cell Biol 7: 823-830, 2005. (Pubitemid 41079055)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.8
, pp. 823-830
-
-
Wang, W.1
Budhu, A.2
Forgues, M.3
Wang, X.W.4
-
45
-
-
0033556262
-
Suppression of host immune response by the core protein of hepatitis C virus: Possible implications for hepatitis C virus persistence
-
Large MK, Kittlesen DJ and Hahn YS: Suppression of host immune response by the core protein of hepatitis C virus: possible implications for hepatitis C virus persistence. J Immunol 162: 931-938, 1999. (Pubitemid 29035418)
-
(1999)
Journal of Immunology
, vol.162
, Issue.2
, pp. 931-938
-
-
Large, M.K.1
Kittlesen, D.J.2
Hahn, Y.S.3
-
46
-
-
0032906988
-
Hepatitis C virus core protein enhances NF-κB signal pathway triggering by lymphotoxinbeta receptor ligand and tumor necrosis factor alfa
-
You LR, Chen CM and Lee YHW: Hepatitis C virus core protein enhances NF-κB signal pathway triggering by lymphotoxinbeta receptor ligand and tumor necrosis factor alfa. J Virol 73: 1672-1681, 1999.
-
(1999)
J Virol
, vol.73
, pp. 1672-1681
-
-
You, L.R.1
Chen, C.M.2
Lee, Y.H.W.3
-
47
-
-
0035916008
-
Hepatitis C virus core protein inhibits interleukin 12 and nitric oxide production from activated macrophages
-
DOI 10.1006/viro.2000.0694
-
Lee CH, Choi YH, Yang SH, Lee CW, Ha SJ and Sung YC: Hepatitis C virus core protein inhibits interleukin 12 and nitric oxide production from activated macrophages. Virology 279: 271-279, 2001. (Pubitemid 34161017)
-
(2001)
Virology
, vol.279
, Issue.1
, pp. 271-279
-
-
Lee, C.H.1
Choi, Y.H.2
Yang, S.-H.3
Lee, C.W.4
Ha, S.J.5
Sung, Y.C.6
-
48
-
-
33746467483
-
Effect of hepatitis C virus core protein on the molecular profiling of human B lymphocytes
-
DOI 10.2119/2006-00020.Wu
-
Wu CG, Budhu A, Chen S, Zhou X, Popescu NC, Valerie K and Wang XW: Effect of hepatitis C virus core protein on the molecular profiling of human B lymphocyte. Mol Med 12: 47-53, 2006. (Pubitemid 44128377)
-
(2006)
Molecular Medicine
, vol.12
, Issue.1-3
, pp. 47-53
-
-
Wu, C.-G.1
Budhu, A.2
Chen, S.3
Zhou, X.4
Popescu, N.C.5
Valerie, K.6
Wang, X.W.7
-
49
-
-
0034691609
-
Hepatitis C virus glycoprotein E2 binding to CD81: The role of E1E2 cleavage and protein glycosylation in bioactivity
-
DOI 10.1006/viro.2000.0407
-
Chan-Fook C, Jiang WR, Clarke BE, Zitzmann N, Maidens C, McKeating JA and Jones IM: Hepatitis C virus glycoprotein E2 binding to CD81: the role of E1E2 cleavage and protein glycosylation in bioactivity. Virology 273: 60-66, 2000. (Pubitemid 30602008)
-
(2000)
Virology
, vol.273
, Issue.1
, pp. 60-66
-
-
Chan-Fook, C.1
Jiang, W.-R.2
Clarke, B.E.3
Zitzmann, N.4
Maidens, C.5
McKeating, J.A.6
Jones, I.M.7
-
50
-
-
0036017204
-
The nonstructural NS5A protein of hepatitis C virus: An expanding, multifunctional role in enhancing hepatitis C virus pathogenesis
-
Reyes GR: The nonstructural NS5A protein of hepatitis C virus: an expanding, multifunctional role in enhancing hepatitis C virus pathogenesis. J Biomed Sci 9: 187-197, 2002.
-
(2002)
J Biomed Sci
, vol.9
, pp. 187-197
-
-
Reyes, G.R.1
-
51
-
-
0036432759
-
The hepatitis B virus X protein binds to and activates the NH(2)-terminal trans-activation domain of nuclear factor of activated T cells-1
-
Carretero M, Gomez-Gonzalo M, Lara-Pezzi E, Benedicto I, Aramburu J, Martinez-Martinez S, Redondo J and Lopez- Cabrera M: The hepatitis B virus X protein binds to and activates the NH(2)-terminal trans-activation domain of nuclear factor of activated T cells-1. Virology 299: 288-300, 2002.
-
(2002)
Virology
, vol.299
, pp. 288-300
-
-
Carretero, M.1
Gomez-Gonzalo, M.2
Lara-Pezzi, E.3
Benedicto, I.4
Aramburu, J.5
Martinez-Martinez, S.6
Redondo, J.7
Lopez- Cabrera, M.8
-
52
-
-
0038103068
-
Low frequency of bcl-2 rearrangement in HCV-associated non-Hodgkin's lymphoma tissue [12]
-
DOI 10.1038/sj.leu.2402968
-
Libra M, De Re V, De Vita S, Gasparotto D, Gloghini A, Rupolo M, Degan M, Marzotto A, Stivala F, Carbone A and Boiocchi M: Low frequency of bcl-2 rearrangement in HCV-associated non-Hodgkin's lymphoma tissue. Leukemia 17: 1433-1436, 2003. (Pubitemid 36857363)
-
(2003)
Leukemia
, vol.17
, Issue.7
, pp. 1433-1436
-
-
Libra, M.1
De Re, V.2
De Vita, S.3
Gasparotto, D.4
Gloghini, A.5
Rupolo, M.6
Degan, M.7
Marzotto, A.8
Stivala, F.9
Carbone, A.10
Boiocchi, M.11
-
53
-
-
3242798980
-
Detection of bcl-2 rearrangement in mucosa-associated lymphoid tissue lymphomas from patients with hepatitis C virus infection
-
Libra M, De Re V, Gloghini A, Gasparotto D, Gragnani L, Navolanic PM, De Vita S, Mazzarino MC, Zignego AL, Carbone A and Boiocchi M: Detection of bcl-2 rearrangement in mucosaassociated lymphoid tissue lymphomas from patients with hepatitis C virus infection. Haematologica 89: 873-874, 2004. (Pubitemid 38981354)
-
(2004)
Haematologica
, vol.89
, Issue.7
, pp. 873-874
-
-
Libra, M.1
De Re, V.2
Gloghini, A.3
Gasparotto, D.4
Gragnani, L.5
Navolanic, P.M.6
De Vita, S.7
Mazzarino, M.C.8
Zignego, A.L.9
Carbone, A.10
Boiocchi, M.11
-
54
-
-
33646426905
-
Elevated serum levels of osteopontin in HCV-associated lymphoproliferative disorders
-
Libra M, Indelicato M, De Re V, Zignego AL, Chiocchetti A, Malaponte G, Dianzani U, Nicoletti F, Stivala F, McCubrey JA and Mazzarino MC: Elevated serum levels of osteopontin in HCV-associated lymphoproliferative disorders. Cancer Biol Ther 4: 1192-1194, 2005.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1192-1194
-
-
Libra, M.1
Indelicato, M.2
De Re, V.3
Zignego, A.L.4
Chiocchetti, A.5
Malaponte, G.6
Dianzani, U.7
Nicoletti, F.8
Stivala, F.9
McCubrey, J.A.10
Mazzarino, M.C.11
-
55
-
-
20944433443
-
Analysis of aberrant somatic hypermutation (SHM) in non-Hodgkin's lymphomas of patients with chronic HCV infection
-
DOI 10.1002/path.1754
-
Libra M, Capello D, Gloghini A, Laura P, Berra E, Cerri M, Gasparotto D, Franca S, De Re V, Gaidano G and Carbone A: Analysis of aberrant somatic hypermutation (SHM) in non-Hodgkin's lymphomas of patients with chronic HCV infection. J Pathol 206: 87-91, 2005. (Pubitemid 40613438)
-
(2005)
Journal of Pathology
, vol.206
, Issue.1
, pp. 87-91
-
-
Libra, M.1
Capello, D.2
Gloghini, A.3
Laura, P.4
Berra, E.5
Cerri, M.6
Gasparotto, D.7
Franca, S.8
De Re, V.9
Gaidano, G.10
Carbone, A.11
-
56
-
-
21344441380
-
Aggressive forms of non-Hodgkin's lymphoma in two patients bearing coinfection of Epstein-Barr and hepatitis C viruses
-
Libra M, Gloghini A, De Re V, Rupolo M, Navolanic PM, Gasparotto D, Stivala F, Spina M, Boiocchi M and Carbone A: Aggressive forms of non-Hodgkin's lymphoma in two patients bearing coinfection of Epstein-Barr and hepatitis C viruses. Int J Oncol 26: 945-950, 2005.
-
(2005)
Int J Oncol
, vol.26
, pp. 945-950
-
-
Libra, M.1
Gloghini, A.2
De Re, V.3
Rupolo, M.4
Navolanic, P.M.5
Gasparotto, D.6
Stivala, F.7
Spina, M.8
Boiocchi, M.9
Carbone, A.10
-
57
-
-
33744989717
-
Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV-associated lymphoproliferative disorders
-
Libra M, Mangano K, Anzaldi M, Quattrocchi C, Donia M, Di Marco R, Signorelli S, Scalia G, Zignego AL, De Re V, Mazzarino MC and Nicoletti F: Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV-associated lymphoproliferative disorders. Oncol Rep 15: 1305-1308, 2006.
-
(2006)
Oncol Rep
, vol.15
, pp. 1305-1308
-
-
Libra, M.1
Mangano, K.2
Anzaldi, M.3
Quattrocchi, C.4
Donia, M.5
Di Marco, R.6
Signorelli, S.7
Scalia, G.8
Zignego, A.L.9
De Re, V.10
Mazzarino, M.C.11
Nicoletti, F.12
-
58
-
-
46149120101
-
Association of t(14;18) translocation with HCV infection in gastrointestinal MALT lymphomas
-
Libra M, Gloghini A, Malaponte G, Gangemi P, De Re V, Cacopardo B, Spandidos DA, Nicoletti F, Stivala F, Zignego AL and Carbone A: Association of t(14;18) translocation with HCV infection in gastrointestinal MALT lymphomas. J Hepatol 49: 170-174, 2008.
-
(2008)
J Hepatol
, vol.49
, pp. 170-174
-
-
Libra, M.1
Gloghini, A.2
Malaponte, G.3
Gangemi, P.4
De Re, V.5
Cacopardo, B.6
Spandidos, D.A.7
Nicoletti, F.8
Stivala, F.9
Zignego, A.L.10
Carbone, A.11
-
59
-
-
35148863475
-
Genetic insights into the disease mechanisms of type II mixed cryoglobulinemia induced by hepatitis C virus
-
De Re V, Caggiari L, De Vita S, Mazzaro C, Lenzi M, Galli M, Monti G, Ferri C, Zignego AL, Gabrielli A, Sansonno D, Dammacco F, Libra M, Sacchi N, Talamini R, Spina M, Cannizzaro R, Guidoboni M and Dolcetti R: Genetic insights into the disease mechanisms of type II mixed cryoglobulinemia induced by hepatitis C virus. Dig Liver Dis 39: 65-71, 2007.
-
(2007)
Dig Liver Dis
, vol.39
, pp. 65-71
-
-
De Re, V.1
Caggiari, L.2
De Vita, S.3
Mazzaro, C.4
Lenzi, M.5
Galli, M.6
Monti, G.7
Ferri, C.8
Zignego, A.L.9
Gabrielli, A.10
Sansonno, D.11
Dammacco, F.12
Libra, M.13
Sacchi, N.14
Talamini, R.15
Spina, M.16
Cannizzaro, R.17
Guidoboni, M.18
Dolcetti, R.19
-
60
-
-
34648817580
-
Role of the HLA class II: HCV-related disorders
-
DOI 10.1196/annals.1381.033, Autoimmunity, Part C The Mosaic of Autoimmunity
-
De Re V, Caggiari L, Simula MP, De Vita S, Mazzaro C, Lenzi M, Massimo GM, Monti G, Ferri C, Zignego AL, Gabrielli A, Sansonno D, Dammacco F, Libra M, Sacchi N, Talamini R, Spina M, Tirelli U, Cannizzaro R and Dolcetti R: Role of the HLA class II: HCV-related disorders. Ann NY Acad Sci 1107: 308-318, 2007. (Pubitemid 47528808)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1107
, pp. 308-318
-
-
De Re, V.1
Caggiari, L.2
Simula, M.P.3
De Vita, S.4
Mazzaro, C.5
Lenzi, M.6
Galli, M.M.7
Monti, G.8
Ferri, C.9
Zignego, A.L.10
Gabrielli, A.11
Sansonno, D.12
Dammacco, F.13
Libra, M.14
Sacchi, N.15
Talamini, R.16
Spina, M.17
Tirelli, U.18
Cannizzaro, R.19
Dolcetti, R.20
more..
-
61
-
-
73949089660
-
HLA DR-DQ combination associated with the increased risk of developing human HCV positive non-Hodgkin's lymphoma is related to the type II mixed cryoglobulinemia
-
De Re V, Caggiari L, Monti G, Libra M, Spina M, Dolcetti R, De Zorzi M, Racanelli V, Crovatto M and Toffoli G: HLA DR-DQ combination associated with the increased risk of developing human HCV positive non-Hodgkin's lymphoma is related to the type II mixed cryoglobulinemia. Tissue Antigens 75: 127-135, 2010.
-
(2010)
Tissue Antigens
, vol.75
, pp. 127-135
-
-
De Re, V.1
Caggiari, L.2
Monti, G.3
Libra, M.4
Spina, M.5
Dolcetti, R.6
De Zorzi, M.7
Racanelli, V.8
Crovatto, M.9
Toffoli, G.10
-
62
-
-
77951586549
-
Extrahepatic disorders of HCV infection: A distinct entity of B-cell neoplasia?
-
Libra M, Polesel J, Russo AE, De Re V, Cinà D, Serraino D, Nicoletti F, Spandidos DA, Stivala F and Talamini R: Extrahepatic disorders of HCV infection: a distinct entity of B-cell neoplasia? Int J Oncol 36: 1331-1340, 2010.
-
(2010)
Int J Oncol
, vol.36
, pp. 1331-1340
-
-
Libra, M.1
Polesel, J.2
Russo, A.E.3
De Re, V.4
Cinà, D.5
Serraino, D.6
Nicoletti, F.7
Spandidos, D.A.8
Stivala, F.9
Talamini, R.10
-
64
-
-
60949101225
-
Cancer-associated fibroblasts and tumor growth-bystanders turning into key players
-
Ostman A and Augsten M: Cancer-associated fibroblasts and tumor growth-bystanders turning into key players. Curr Opin Genet Dev 19: 67-73, 2009.
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 67-73
-
-
Ostman, A.1
Augsten, M.2
-
65
-
-
77952568396
-
Hallmarks of cancer: Interactions with the tumor stroma
-
Pietras K and Ostman A: Hallmarks of cancer: interactions with the tumor stroma. Exp Cell Res 316: 1324-1331, 2010.
-
(2010)
Exp Cell Res
, vol.316
, pp. 1324-1331
-
-
Pietras, K.1
Ostman, A.2
-
66
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
DOI 10.1038/nature03096
-
Bhowmick NA, Neilson EG and Moses HL: Stromal fibroblasts in cancer initiation and progression. Nature 432: 332-337, 2004. (Pubitemid 39551661)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
67
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
-
Orimo A, Gupta PB, Sgroi DC, et al: Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121: 335-348, 2005. (Pubitemid 40692295)
-
(2005)
Cell
, vol.121
, Issue.3
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
68
-
-
33846916208
-
Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma
-
DOI 10.1200/JCO.2006.07.8824
-
Infante JR, Matsubayashi H, Sato N, Tonascia J, Klein AP, Riall TA, Yeo C, Iacobuzio-Donahue C and Goggins M: Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma. J Clin Oncol 25: 319-325, 2007. (Pubitemid 350003021)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.3
, pp. 319-325
-
-
Infante, J.R.1
Matsubayashi, H.2
Sato, N.3
Tonascia, J.4
Klein, A.P.5
Riall, T.A.6
Yeo, C.7
Iacobuzio-Donahue, C.8
Goggins, M.9
-
69
-
-
36349034540
-
Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment
-
DOI 10.2353/ajpath.2007.060661
-
Mueller L, Goumas FA, Affeldt M, et al: Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment. Am J Pathol 171: 1608-1618, 2007. (Pubitemid 350158321)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.5
, pp. 1608-1618
-
-
Mueller, L.1
Goumas, F.A.2
Affeldt, M.3
Sandtner, S.4
Gehling, U.M.5
Brilloff, S.6
Walter, J.7
Karnatz, N.8
Lamszus, K.9
Rogiers, X.10
Broering, D.C.11
-
70
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
DOI 10.1038/ncb1658, PII NCB1658
-
Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K and Sahai E: Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 9: 1392-1400, 2007. (Pubitemid 350201752)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.12
, pp. 1392-1400
-
-
Gaggioli, C.1
Hooper, S.2
Hidalgo-Carcedo, C.3
Grosse, R.4
Marshall, J.F.5
Harrington, K.6
Sahai, E.7
-
71
-
-
63349088695
-
Targeting transforming growth factor (TGF)-betaRI inhibits activation of beta1 integrin and blocks vascular invasion in hepatocellular carcinoma
-
Fransvea E, Mazzocca A, Antonaci S and Giannelli G: Targeting transforming growth factor (TGF)-betaRI inhibits activation of beta1 integrin and blocks vascular invasion in hepatocellular carcinoma. Hepatology 49: 839-850, 2009.
-
(2009)
Hepatology
, vol.49
, pp. 839-850
-
-
Fransvea, E.1
Mazzocca, A.2
Antonaci, S.3
Giannelli, G.4
-
72
-
-
0001520008
-
Hepatic lipocytes: The principal collagen-producing cells of normal rat liver
-
Friedman SL, Roll FJ, Boyles J and Bissell DM: Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci USA 82: 8681-8685, 1985. (Pubitemid 16101107)
-
(1985)
Proceedings of the National Academy of Sciences of the United States of America
, vol.82
, Issue.24
, pp. 8681-8685
-
-
Friedman, S.L.1
Roll, F.J.2
Boyles, J.3
Bissell, D.M.4
-
73
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
Wynn TA: Cellular and molecular mechanisms of fibrosis. J Pathol 214: 199-210, 2008.
-
(2008)
J Pathol
, vol.214
, pp. 199-210
-
-
Wynn, T.A.1
-
75
-
-
35948954244
-
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
-
Friedman SL: Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 88: 125-172, 2008.
-
(2008)
Physiol Rev
, vol.88
, pp. 125-172
-
-
Friedman, S.L.1
-
76
-
-
0035064480
-
Expression and cellular localization of fibrillin-1 in normal and pathological human liver
-
DOI 10.1016/S0168-8278(00)00048-9, PII S0168827800000489
-
Dubuisson L, Lepreux S, Bioulac-Sage P, Balabaud C, Costa AM, Rosenbaum J and Desmoulière A: Expression and cellular localization of fibrillin-1 in normal and pathological human liver. J Hepatol 34: 514-522, 2001. (Pubitemid 32328507)
-
(2001)
Journal of Hepatology
, vol.34
, Issue.4
, pp. 514-522
-
-
Dubuisson, L.1
Lepreux, S.2
Bioulac-Sage, P.3
Balabaud, C.4
Costa, A.M.A.5
Rosenbaum, J.6
Desmouliere, A.7
-
77
-
-
74049086775
-
Gene expression profiles during activation of cultured rat hepatic stellate cells by tumoral hepatocytes and fetal bovine serum
-
Xia Y, Chen R, Song Z, Ye S, Sun R, Xue Q and Zhang Z: Gene expression profiles during activation of cultured rat hepatic stellate cells by tumoral hepatocytes and fetal bovine serum. J Cancer Res Clin Oncol 136: 309-321, 2010.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 309-321
-
-
Xia, Y.1
Chen, R.2
Song, Z.3
Ye, S.4
Sun, R.5
Xue, Q.6
Zhang, Z.7
-
78
-
-
73349108444
-
Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells
-
Sancho-Bru P, Juez E, Moreno M, et al: Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells. Liver Int 30: 31-41, 2010.
-
(2010)
Liver Int
, vol.30
, pp. 31-41
-
-
Sancho-Bru, P.1
Juez, E.2
Moreno, M.3
-
79
-
-
0029935071
-
Type I procollagen production and cell proliferation is mediated by transforming growth factor-beta in a model of hepatic fibrosis
-
DOI 10.1210/en.137.5.1894
-
Eghbali-Fatourechi G, Sieck GC, Prakash YS, Maercklein P, Gores GJ and Fitzpatrick LA: Type I procollagen production and cell proliferation is mediated by transforming growth factor-beta in a model of hepatic fibrosis. Endocrinology 137: 1894-1903, 1996. (Pubitemid 26133966)
-
(1996)
Endocrinology
, vol.137
, Issue.5
, pp. 1894-1903
-
-
Eghbali-Fatourechi, G.1
Sieck, G.C.2
Prakash, Y.S.3
Maercklein, P.4
Gores, G.J.5
Fitzpatrick, L.A.6
-
80
-
-
20044385758
-
Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma
-
DOI 10.1073/pnas.0409722102
-
Campbell JS, Hughes SD, Gilbertson DG, et al: Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. Proc Natl Acad Sci USA 102: 3389-3394, 2005. (Pubitemid 40328055)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.9
, pp. 3389-3394
-
-
Campbell, J.S.1
Hughes, S.D.2
Gilbertson, D.G.3
Palmer, T.E.4
Holdren, M.S.5
Haran, A.C.6
Odell, M.M.7
Bauer, R.L.8
Ren, H.-P.9
Haugen, H.S.10
Yeh, M.M.11
Fausto, N.12
-
81
-
-
33645798836
-
Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice
-
DOI 10.1096/fj.05-4828com
-
Roderfeld M, Weiskirchen R, Wagner S, Berres ML, Henkel C, Grötzinger J, Gressner AM, Matern S and Roeb E: Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice. FASEB J 20: 444-454, 2006. (Pubitemid 44933321)
-
(2006)
FASEB Journal
, vol.20
, Issue.3
, pp. 444-454
-
-
Roderfeld, M.1
Weiskirchen, R.2
Wagner, S.3
Berres, M.-L.4
Henkel, C.5
Grotzinger, J.6
Gressner, A.M.7
Matern, S.8
Roeb, E.9
-
82
-
-
22344452756
-
Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells
-
DOI 10.1053/j.gastro.2005.03.089, PII S0016508505008942
-
Schulze-Krebs A, Preimel D, Popov Y, Bartenschlager R, Lohmann V, Pinzani M and Schuppan D: Hepatitis C virusreplicating hepatocytes induce fibrogenic activation of hepatic stellate cells. Gastroenterology 129: 246-258, 2005. (Pubitemid 41002058)
-
(2005)
Gastroenterology
, vol.129
, Issue.1
, pp. 246-258
-
-
Schulze-Krebs, A.1
Preimel, D.2
Popov, Y.3
Bartenschlager, R.4
Lohmann, V.5
Pinzani, M.6
Schuppan, D.7
-
83
-
-
46249101267
-
The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells
-
DOI 10.1002/hep.22265
-
Martín-Vílchez S, Sanz-Cameno P, Rodríguez- Muñoz Y, Majano PL, Molina-Jiménez F, López-Cabrera M, Moreno- Otero R and Lara-Pezzi E: The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells. Hepatology 47: 1872-1883, 2008. (Pubitemid 351945555)
-
(2008)
Hepatology
, vol.47
, Issue.6
, pp. 1872-1883
-
-
Martin-Vilchez, S.1
Sanz-Cameno, P.2
Rodriguez-Munoz, Y.3
Majano, P.L.4
Molina-Jimenez, F.5
Lopez-Cabrera, M.6
Moreno-Otero, R.7
Lara-Pezzi, E.8
-
84
-
-
51349133312
-
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways
-
Nitta T, Kim JS, Mohuczy D and Behrns KE: Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways. Hepatology 48: 909-919, 2008.
-
(2008)
Hepatology
, vol.48
, pp. 909-919
-
-
Nitta, T.1
Kim, J.S.2
Mohuczy, D.3
Behrns, K.E.4
-
85
-
-
72249114470
-
Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition
-
Kluwe J, Pradere JP, Gwak GY, Mencin A, De Minicis S, Osterreicher CH, Colmenero J, Bataller R and Schwabe RF: Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition. Gastroenterology 138: 347-359, 2010.
-
(2010)
Gastroenterology
, vol.138
, pp. 347-359
-
-
Kluwe, J.1
Pradere, J.P.2
Gwak, G.Y.3
Mencin, A.4
De Minicis, S.5
Osterreicher, C.H.6
Colmenero, J.7
Bataller, R.8
Schwabe, R.F.9
-
86
-
-
65449128051
-
Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential
-
Moles A, Tarrats N, Fernandez-Checa JC and Mari M: Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential. Hepatology 49: 1297-1307, 2009.
-
(2009)
Hepatology
, vol.49
, pp. 1297-1307
-
-
Moles, A.1
Tarrats, N.2
Fernandez-Checa, J.C.3
Mari, M.4
-
87
-
-
79952042322
-
Insulin-like growth factor binding protein 5 enhances survival of LX2 human hepatic stellate cells
-
Sokolovic A, Sokolovic M, Boers W, Elferink RP and Bosma PJ: Insulin-like growth factor binding protein 5 enhances survival of LX2 human hepatic stellate cells. Fibrogenesis Tissue Repair 3: 3, 2010.
-
(2010)
Fibrogenesis Tissue Repair
, vol.3
, pp. 3
-
-
Sokolovic, A.1
Sokolovic, M.2
Boers, W.3
Elferink, R.P.4
Bosma, P.J.5
-
88
-
-
0026689558
-
The origin and function of tumor-associated macrophages
-
Mantovani A, Bottazzi B, Colotta F, Sozzani S and Ruco L: The origin and function of tumor-associated macrophages. Immunol Today 13: 265-270, 1992.
-
(1992)
Immunol Today
, vol.13
, pp. 265-270
-
-
Mantovani, A.1
Bottazzi, B.2
Colotta, F.3
Sozzani, S.4
Ruco, L.5
-
89
-
-
35448954376
-
Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
-
DOI 10.1158/0008-5472.CAN-07-2354
-
Bunt SK, Yang L, Sinha P, Clements VK, Leips J and Ostrand-Rosenberg S: Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res 67: 10019-10026, 2007. (Pubitemid 47621253)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 10019-10026
-
-
Bunt, S.K.1
Yang, L.2
Sinha, P.3
Clements, V.K.4
Leips, J.5
Ostrand-Rosenberg, S.6
-
90
-
-
0034721666
-
MMP-9 supplied by bone marrow derived cells contributes to skin carcinogenesis
-
Coussens LM, Tinkle CL, Hanahan D and Werb Z: MMP-9 supplied by bone marrow derived cells contributes to skin carcinogenesis. Cell 103: 481-490, 2000.
-
(2000)
Cell
, vol.103
, pp. 481-490
-
-
Coussens, L.M.1
Tinkle, C.L.2
Hanahan, D.3
Werb, Z.4
-
91
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
DOI 10.1016/S1471-4906(02)02302-5, PII S1471490602023025
-
Mantovani A, Sozzani S, Locati M, Allavena P and Sica A: Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23: 549-555, 2002. (Pubitemid 35223554)
-
(2002)
Trends in Immunology
, vol.23
, Issue.11
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
92
-
-
65049084189
-
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation
-
Mantovani A, Sica A, Allavena P, Garlanda C and Locati M: Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum Immunol 70: 325-330, 2009.
-
(2009)
Hum Immunol
, vol.70
, pp. 325-330
-
-
Mantovani, A.1
Sica, A.2
Allavena, P.3
Garlanda, C.4
Locati, M.5
-
93
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
-
Biswas SK and Mantovani A: Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 11: 889-896, 2010.
-
(2010)
Nat Immunol
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
94
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI and Nagaraj S: Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9: 162-174, 2009.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
95
-
-
77955038532
-
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes
-
Movahedi K, Laoui D, Gysemans C, Baeten M, Stangè G, van den Bossche J, Mack M, Pipeleers D, In't Veld P, De Baetselier P and van Ginderachter JA: Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes. Cancer Res 70: 5728-5739, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 5728-5739
-
-
Movahedi, K.1
Laoui, D.2
Gysemans, C.3
Baeten, M.4
Stangè, G.5
Van Den Bossche, J.6
Mack, M.7
Pipeleers, D.8
In't Veld, P.9
De Baetselier, P.10
Van Ginderachter, J.A.11
-
96
-
-
0035197719
-
Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12
-
DOI 10.1053/jhep.2001.20796
-
Barajas M, Mazzolini G, Genove G, Bilbao R, Narvaiza I, Schmitz V, Sangro B, Melero I, Qian C and Prieto J: Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12. Hepatology 33: 52-61, 2001. (Pubitemid 32016887)
-
(2001)
Hepatology
, vol.33
, Issue.1
, pp. 52-61
-
-
Barajas, M.1
Mazzolini, G.2
Genovie, G.3
Bilbao, R.4
Narvaiza, I.5
Schmitz, V.6
Sangro, B.7
Melero, I.8
Qian, C.9
Prieto, J.10
-
97
-
-
70350234729
-
Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions
-
Wu K, Kryczek I, Chen L, Zou W and Welling TH: Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions. Cancer Res 69: 8067-8075, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 8067-8075
-
-
Wu, K.1
Kryczek, I.2
Chen, L.3
Zou, W.4
Welling, T.H.5
-
98
-
-
42149085600
-
Reviews: Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer
-
DOI 10.1093/toxsci/kfm246
-
Ramaiah SK and Rittling S: Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer. Toxicol Sci 103: 4-13, 2008. (Pubitemid 351524472)
-
(2008)
Toxicological Sciences
, vol.103
, Issue.1
, pp. 4-13
-
-
Ramaiah, S.K.1
Rittling, S.2
-
99
-
-
58149348622
-
Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression
-
Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P, Travali S, Stivala F, Canevari S and Libra M: Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression. Clin Cancer Res 14: 7470-7480, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7470-7480
-
-
Castellano, G.1
Malaponte, G.2
Mazzarino, M.C.3
Figini, M.4
Marchese, F.5
Gangemi, P.6
Travali, S.7
Stivala, F.8
Canevari, S.9
Libra, M.10
-
100
-
-
33847650413
-
Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes?
-
DOI 10.1016/j.coi.2007.02.001, PII S095279150700009X, Lymphocyte development/Tumour immunology
-
Bui JD and Schreiber RD: Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes? Curr Opin Immunol 19: 203-208, 2007. (Pubitemid 46356963)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.2
, pp. 203-208
-
-
Bui, J.D.1
Schreiber, R.D.2
-
101
-
-
0348223787
-
+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 198: 1875-1886, 2003.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
102
-
-
34250005419
-
Increased Regulatory T Cells Correlate With CD8 T-Cell Impairment and Poor Survival in Hepatocellular Carcinoma Patients
-
DOI 10.1053/j.gastro.2007.03.102, PII S0016508507006282
-
Fu J, Xu D, Liu Z, et al: Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients. Gastroenterology 132: 2328-2339, 2007. (Pubitemid 46890865)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2328-2339
-
-
Fu, J.1
Xu, D.2
Liu, Z.3
Shi, M.4
Zhao, P.5
Fu, B.6
Zhang, Z.7
Yang, H.8
Zhang, H.9
Zhou, C.10
Yao, J.11
Jin, L.12
Wang, H.13
Yang, Y.14
Fu, Y.-X.15
Wang, F.-S.16
-
103
-
-
34447277894
-
Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
-
DOI 10.1200/JCO.2006.09.4565
-
Gao Q, Qiu SJ, Fan J, Zhou J, Wang XY, Xiao YS, Xu Y, Li YW and Tang ZY: Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol 25: 2586-2593, 2007. (Pubitemid 47041232)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.18
, pp. 2586-2593
-
-
Gao, Q.1
Qiu, S.-J.2
Fan, J.3
Zhou, J.4
Wang, X.-Y.5
Xiao, Y.-S.6
Xu, Y.7
Li, Y.-W.8
Tang, Z.-Y.9
-
104
-
-
77957607351
-
Increased prevalence of regulatory T cells in the tumor microenvironment and its correlation with TNM stage of hepatocellular carcinoma
-
Shen X, Li N, Li H, Zhang T, Wang F and Li Q: Increased prevalence of regulatory T cells in the tumor microenvironment and its correlation with TNM stage of hepatocellular carcinoma. J Cancer Res Clin Oncol 136: 1745-1754, 2010.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 1745-1754
-
-
Shen, X.1
Li, N.2
Li, H.3
Zhang, T.4
Wang, F.5
Li, Q.6
-
105
-
-
69849107597
-
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
-
Kryczek I, Banerjee M, Cheng P, Vatan L, Szeliga W, Wei S, Huang E, Finlayson E, Simeone D, Welling TH, Chang A, Coukos G, Liu R and Zou W: Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 114: 1141-1149, 2009.
-
(2009)
Blood
, vol.114
, pp. 1141-1149
-
-
Kryczek, I.1
Banerjee, M.2
Cheng, P.3
Vatan, L.4
Szeliga, W.5
Wei, S.6
Huang, E.7
Finlayson, E.8
Simeone, D.9
Welling, T.H.10
Chang, A.11
Coukos, G.12
Liu, R.13
Zou, W.14
-
106
-
-
55149114870
-
Th17 and cancer: Friends or foes?
-
Bronte V: Th17 and cancer: friends or foes? Blood 112: 214, 2008.
-
(2008)
Blood
, vol.112
, pp. 214
-
-
Bronte, V.1
-
107
-
-
70449715722
-
Protumor vs antitumor functions of IL-17
-
Murugaiyan G and Saha B: Protumor vs antitumor functions of IL-17. J Immunol 183: 4169-4175, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 4169-4175
-
-
Murugaiyan, G.1
Saha, B.2
-
108
-
-
64549108462
-
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
-
Zhang JP, Yan J, Xu J, Pang XH, Chen MS, Li L, Wu C, Li SP and Zheng L: Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol 50: 980-989, 2009.
-
(2009)
J Hepatol
, vol.50
, pp. 980-989
-
-
Zhang, J.P.1
Yan, J.2
Xu, J.3
Pang, X.H.4
Chen, M.S.5
Li, L.6
Wu, C.7
Li, S.P.8
Zheng, L.9
-
109
-
-
31544467539
-
Molecular fingerprinting and autocrine growth regulation of endothelial cells in a murine model of hepatocellular carcinoma
-
DOI 10.1158/0008-5472.CAN-05-1636
-
Ryschich E, Lizdenis P, Ittrich C, et al: Molecular fingerprinting and autocrine growth regulation of endothelial cells in a murine model of hepatocellular carcinoma. Cancer Res 66: 198-211, 2006. (Pubitemid 43166026)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 198-211
-
-
Ryschich, E.1
Lizdenis, P.2
Ittrich, C.3
Benner, A.4
Stahl, S.5
Hamann, A.6
Schmidt, J.7
Knolle, P.8
Arnold, B.9
Hammerling, G.J.10
Ganss, R.11
-
110
-
-
33644546368
-
Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors
-
Amin DN, Hida K, Bielenberg DR and Klagsbrun M: Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors. Cancer Res 66: 2173-2180, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 2173-2180
-
-
Amin, D.N.1
Hida, K.2
Bielenberg, D.R.3
Klagsbrun, M.4
-
111
-
-
33748697185
-
Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation
-
DOI 10.1182/blood-2006-04-014894
-
Rolny C, Nilsson I, Magnusson P, et al: Platelet-derived growth factor receptor beta promotes early endothelial cell differentiation. Blood 108: 1877-1886, 2006. (Pubitemid 44394997)
-
(2006)
Blood
, vol.108
, Issue.6
, pp. 1877-1886
-
-
Rolny, C.1
Nilsson, I.2
Magnusson, P.3
Armulik, A.4
Jakobsson, L.5
Wentzel, P.6
Lindblom, P.7
Norlin, J.8
Betsholtz, C.9
Heuchel, R.10
Welsh, M.11
Claesson-Welsh, L.12
-
112
-
-
33744458204
-
The dynamic roles of angiopoietins in tumor angiogenesis
-
Yu Q: The dynamic roles of angiopoietins in tumor angiogenesis. Future Oncol 1: 475-484, 2005.
-
(2005)
Future Oncol
, vol.1
, pp. 475-484
-
-
Yu, Q.1
-
113
-
-
54249139202
-
Transforming growth factor-beta1 and CD105 promote the migration of hepatocellular carcinoma-derived endothelium
-
Benetti A, Berenzi A, Gambarotti M, Garrafa E, Gelati M, Dessy E, Portolani N, Piardi T, Giulini SM, Caruso A, Invernici G, Parati EA, Nicosia R and Alessandri G: Transforming growth factor-beta1 and CD105 promote the migration of hepatocellular carcinoma-derived endothelium. Cancer Res 68: 8626-8634, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 8626-8634
-
-
Benetti, A.1
Berenzi, A.2
Gambarotti, M.3
Garrafa, E.4
Gelati, M.5
Dessy, E.6
Portolani, N.7
Piardi, T.8
Giulini, S.M.9
Caruso, A.10
Invernici, G.11
Parati, E.A.12
Nicosia, R.13
Alessandri, G.14
-
114
-
-
68049139572
-
Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells
-
Xiong YQ, Sun HC, Zhang W, et al: Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. Clin Cancer Res 15: 4838-4846, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4838-4846
-
-
Xiong, Y.Q.1
Sun, H.C.2
Zhang, W.3
-
115
-
-
38849202330
-
Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting
-
Pietras K, Pahler J, Bergers G and Hanahan D: Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting. PLoS Med 5: e19, 2008.
-
(2008)
PLoS Med
, vol.5
-
-
Pietras, K.1
Pahler, J.2
Bergers, G.3
Hanahan, D.4
-
116
-
-
45749137283
-
High expression of macrophage colony stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma
-
Zhu XD, Zhang JB, Zhuang PY, Zhu HG, Zhang W, Xiong YQ, Wu WZ, Wang L, Tang ZY and Sun HC: High expression of macrophage colony stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol 26: 2707-2716, 2008.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2707-2716
-
-
Zhu, X.D.1
Zhang, J.B.2
Zhuang, P.Y.3
Zhu, H.G.4
Zhang, W.5
Xiong, Y.Q.6
Wu, W.Z.7
Wang, L.8
Tang, Z.Y.9
Sun, H.C.10
-
117
-
-
77949390562
-
Tumor-mediated inhibition of dendritic cell differentiation is mediated by down regulation of protein kinase C beta II expression
-
Farren MR, Carlson LM and Lee KP: Tumor-mediated inhibition of dendritic cell differentiation is mediated by down regulation of protein kinase C beta II expression. Immunol Res 46: 165-176, 2010.
-
(2010)
Immunol Res
, vol.46
, pp. 165-176
-
-
Farren, M.R.1
Carlson, L.M.2
Lee, K.P.3
-
118
-
-
35448992438
-
Hepatoma cells inhibit the differentiation and maturation of dendritic cells and increase the production of regulatory T cells
-
DOI 10.1016/j.imlet.2007.09.003, PII S0165247807002064
-
Li L, Li SP, Min J and Zheng L: Hepatoma cells inhibit the differentiation and maturation of dendritic cells and increase the production of regulatory T cells. Immunol Lett 114: 38-45, 2007. (Pubitemid 47625596)
-
(2007)
Immunology Letters
, vol.114
, Issue.1
, pp. 38-45
-
-
Li, L.1
Li, S.-P.2
Min, J.3
Zheng, L.4
-
119
-
-
67650474215
-
The expression profile of glypican-3 and its relation to macrophage population in human hepatocellular carcinoma
-
Takai H, Kato A, Kato C, Watanabe T, Matsubara K, Suzuki M and Kataoka H: The expression profile of glypican-3 and its relation to macrophage population in human hepatocellular carcinoma. Liver Int 29: 1056-1064, 2009.
-
(2009)
Liver Int
, vol.29
, pp. 1056-1064
-
-
Takai, H.1
Kato, A.2
Kato, C.3
Watanabe, T.4
Matsubara, K.5
Suzuki, M.6
Kataoka, H.7
-
120
-
-
0029992460
-
Expressions of basic fibroblast growth factor and its receptors and their relationship to proliferation of human hepatocellular carcinoma cell lines
-
DOI 10.1053/jhep.1996.v24.pm0008707262
-
Ogasawara S, Yano H, Iemura A, Hisaka T and Kojiro M: Expressions of basic fibroblast growth factor and its receptors and their relationship to proliferation of human hepatocellular carcinoma cell lines. Hepatology 24: 198-205, 1996. (Pubitemid 26249434)
-
(1996)
Hepatology
, vol.24
, Issue.1
, pp. 198-205
-
-
Ogasawara, S.1
Yano, H.2
Iemura, A.3
Hisaka, T.4
Kojiro, M.5
-
121
-
-
0030683506
-
Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: Evidence for a role of hepatocyte growth factor
-
Neaud V, Faouzi S, Guirouilh J, Le Bail B, Balabaud C, Bioulac-Sage P and Rosenbaum J: Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: evidence for a role of hepatocyte growth factor. Hepatology 26: 1458-1466, 1997. (Pubitemid 27520010)
-
(1997)
Hepatology
, vol.26
, Issue.6
, pp. 1458-1466
-
-
Neaud, V.1
Faouzi, S.2
Guirouilh, J.3
Le, B.B.4
Balabaud, C.5
Bioulac-Sage, P.6
Rosenbaum, J.7
-
122
-
-
33644657201
-
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparinbound growth factors and chemokines: Effects on VEGF, FGF-1, and SDF-1
-
Uchimura K, Morimoto-Tomita M, Bistrup A, Li J, Lyon M, Gallagher J, Werb Z and Rosen SD: HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparinbound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. BMC Biochem 7: 2, 2006.
-
(2006)
BMC Biochem
, vol.7
, pp. 2
-
-
Uchimura, K.1
Morimoto-Tomita, M.2
Bistrup, A.3
Li, J.4
Lyon, M.5
Gallagher, J.6
Werb, Z.7
Rosen, S.D.8
-
123
-
-
1842737772
-
QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis
-
DOI 10.1073/pnas.0401028101
-
Wang S, Ai X, Freeman SD, Pownall ME, Lu Q, Kessler DS and Emerson CP Jr: QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signalling in mesoderm induction and angiogenesis. Proc Natl Acad Sci USA 101: 4833-4838, 2004. (Pubitemid 38469163)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.14
, pp. 4833-4838
-
-
Wang, S.1
Ai, X.2
Freeman, S.D.3
Pownall, M.E.4
Lu, Q.5
Kessler, D.S.6
Emerson Jr., C.P.7
-
124
-
-
9144264904
-
hSulf1 Sulfatase Promotes Apoptosis of Hepatocellular Cancer Cells by Decreasing Heparin-Binding Growth Factor Signaling
-
DOI 10.1053/j.gastro.2003.09.043
-
Lai JP, Chien JR, Moser DR, et al: hSulf1 sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparinbinding growth factor signaling. Gastroenterology 126: 231-248, 2004. (Pubitemid 38040739)
-
(2004)
Gastroenterology
, vol.126
, Issue.1 SUPPL. 1
, pp. 231-248
-
-
Lai, J.-P.1
Chien, J.R.2
Moser, D.R.3
Staub, J.K.4
Aderca, I.5
Montoya, D.P.6
Matthews, T.A.7
Nagorney, D.M.8
Cunningham, J.M.9
Smith, D.I.10
Greene, E.L.11
Shridhar, V.12
Roberts, L.R.13
-
125
-
-
42249105195
-
Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma
-
DOI 10.1002/hep.22202
-
Lai JP, Sandhu DS, Yu C, et al: Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma. Hepatology 47: 1211-1222, 2008. (Pubitemid 351547907)
-
(2008)
Hepatology
, vol.47
, Issue.4
, pp. 1211-1222
-
-
Lai, J.-P.1
Sandhu, D.S.2
Yu, C.3
Han, T.4
Moser, C.D.5
Jackson, K.K.6
Guerrero, R.B.7
Aderca, I.8
Isomoto, H.9
Garrity-Park, M.M.10
Zou, H.11
Shire, A.M.12
Nagorney, D.M.13
Sanderson, S.O.14
Adjei, A.A.15
Lee, J.-S.16
Thorgeirsson, S.S.17
Roberts, L.R.18
-
126
-
-
77649218826
-
Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88
-
Hossain MM, Hosono-Fukao T, Tang R, Sugaya N, van Kuppevelt TH, Jenniskens GJ, Kimata K, Rosen SD and Uchimura K: Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88. Glycobiology 20: 175-186, 2010.
-
(2010)
Glycobiology
, vol.20
, pp. 175-186
-
-
Hossain, M.M.1
Hosono-Fukao, T.2
Tang, R.3
Sugaya, N.4
Van Kuppevelt, T.H.5
Jenniskens, G.J.6
Kimata, K.7
Rosen, S.D.8
Uchimura, K.9
-
127
-
-
84984569951
-
Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: A randomized phase II trial for safety and optimal dosage
-
Liu CJ, Lee PH, Lin DY, et al: Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: a randomized phase II trial for safety and optimal dosage. J Hepatol 50: 958-968, 2009.
-
(2009)
J Hepatol
, vol.50
, pp. 958-968
-
-
Liu, C.J.1
Lee, P.H.2
Lin, D.Y.3
-
128
-
-
0345251977
-
Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: An in vivo and in vitro study
-
DOI 10.1016/S0168-8278(99)80074-9
-
Faouzi S, Le Bail B, Neaud V, Boussarie L, Saric J, Bioulac-Sage P, Balabaud C and Rosenbaum J: Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: an in vivo and in vitro study. J Hepatol 30: 275-284, 1999. (Pubitemid 29071192)
-
(1999)
Journal of Hepatology
, vol.30
, Issue.2
, pp. 275-284
-
-
Faouzi, S.1
Bail, B.L.2
Neaud, V.3
Boussarie, L.4
Saric, J.5
Bioulac-Sage, P.6
Balabaud, C.7
Rosenbaum, J.8
-
129
-
-
0030982967
-
Evidence that 'myofibroblast-like' cells are the cellular source of capsular collagen in hepatocellular carcinoma
-
DOI 10.1016/S0168-8278(97)80245-0
-
Ooi LP, Crawford DH, Gotley DC, et al: Evidence that 'myo-fibroblast- like' cells are the cellular source of capsular collagen in hepatocellular carcinoma. J Hepatol 26: 798-807, 1997. (Pubitemid 27145702)
-
(1997)
Journal of Hepatology
, vol.26
, Issue.4
, pp. 798-807
-
-
Ooi, L.P.J.1
Crawford, D.H.G.2
Gotley, D.C.3
Clouston, A.D.4
Strong, R.W.5
Gobe, G.C.6
Halliday, J.W.7
Bridle, K.R.8
Ramm, G.A.9
-
130
-
-
77951623294
-
Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma
-
Ji J, Zhao L, Budhu A, Forgues M, Jia HL, Qin LX, Ye QH, Yu J, Shi X, Tang ZY and Wang XW: Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma. J Hepatol 52: 690-697, 2010.
-
(2010)
J Hepatol
, vol.52
, pp. 690-697
-
-
Ji, J.1
Zhao, L.2
Budhu, A.3
Forgues, M.4
Jia, H.L.5
Qin, L.X.6
Ye, Q.H.7
Yu, J.8
Shi, X.9
Tang, Z.Y.10
Wang, X.W.11
-
131
-
-
42949086409
-
Laminins and their roles in mammals
-
Miner JH: Laminins and their roles in mammals. Microsc Res Tech 71: 349-356, 2008.
-
(2008)
Microsc Res Tech
, vol.71
, pp. 349-356
-
-
Miner, J.H.1
-
132
-
-
0141679409
-
Laminin-5 chains are expressed differentially in metastatic and nonmetastatic hepatocellular carcinoma
-
Giannelli G, Fransvea E, Bergamini C, Marinosci F and Antonaci S: Laminin-5 chains are expressed differentially in metastatic and nonmetastatic hepatocellular carcinoma. Clin Cancer Res 9: 3684-3691, 2003. (Pubitemid 37169236)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.10 I
, pp. 3684-3691
-
-
Giannelli, G.1
Fransvea, E.2
Bergamini, C.3
Marinosci, F.4
Antonaci, S.5
-
133
-
-
27744527762
-
Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma
-
DOI 10.1053/j.gastro.2005.09.055, PII S0016508505019980
-
Giannelli G, Bergamini C, Fransvea E, Sgarra C and Antonaci S: Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma. Gastroenterology 129: 1375-1383, 2005. (Pubitemid 41597379)
-
(2005)
Gastroenterology
, vol.129
, Issue.5
, pp. 1375-1383
-
-
Giannelli, G.1
Bergamini, C.2
Fransvea, E.3
Sgarra, C.4
Antonaci, S.5
-
135
-
-
35048893450
-
Overexpression of integrin beta1 inhibits proliferation of hepatocellular carcinoma cell SMMC-7721 through preventing Skp2-dependent degradation of p27 via PI3K pathway
-
DOI 10.1002/jcb.21323
-
Fu Y, Fang Z, Liang Y, Zhu X, Prins P, Li Z, Wang L, Sun L, Jin J, Yang Y and Zha X: Overexpression of integrin beta 1 inhibits proliferation of hepatocellular carcinoma cell SMMC-7721 through preventing Skp2-dependent degradation of p27 via PI3K pathway. J Cell Biochem 102: 704-718, 2007. (Pubitemid 47557423)
-
(2007)
Journal of Cellular Biochemistry
, vol.102
, Issue.3
, pp. 704-718
-
-
Fu, Y.1
Fang, Z.2
Liang, Y.3
Zhu, X.4
Prins, P.5
Li, Z.6
Wang, L.7
Sun, L.8
Jin, J.9
Yang, Y.10
Zha, X.11
-
136
-
-
0025679064
-
Distinct functions for integrins alpha3beta1 in focal adhesions and alpha6beta4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: Relation to hemidesmosomes
-
Carter WG, Kaur P, Gil SG, Gahr PJ and Wayner EA: Distinct functions for integrins alpha 3 beta 1 in focal adhesions and alpha 6 beta 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes. J Cell Biol 111: 3141-3154, 1990. (Pubitemid 120034049)
-
(1990)
Journal of Cell Biology
, vol.111
, Issue.6 PART 2
, pp. 3141-3154
-
-
Carter, W.G.1
Kaur, P.2
Gil, S.G.3
Gahr, P.J.4
Wayner, E.A.5
-
137
-
-
0035044816
-
Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion
-
Giannelli G, Bergamini C, Fransvea E, Marinosci F, Quaranta V and Antonaci S: Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion. Lab Invest 81: 613-627, 2001. (Pubitemid 32298807)
-
(2001)
Laboratory Investigation
, vol.81
, Issue.4
, pp. 613-627
-
-
Giannelli, G.1
Bergamini, C.2
Fransvea, E.3
Marinosci, F.4
Quaranta, V.5
Antonaci, S.6
-
138
-
-
37749038909
-
Laminin-5 stimulates hepatocellular carcinoma growth through a different function of alpha6beta4 and alpha3beta1 integrins
-
Bergamini C, Sgarra C, Trerotoli P, Lupo L, Azzariti A, Antonaci S and Giannelli G: Laminin-5 stimulates hepatocellular carcinoma growth through a different function of alpha6beta4 and alpha3beta1 integrins. Hepatology 46: 1801-1809, 2007.
-
(2007)
Hepatology
, vol.46
, pp. 1801-1809
-
-
Bergamini, C.1
Sgarra, C.2
Trerotoli, P.3
Lupo, L.4
Azzariti, A.5
Antonaci, S.6
Giannelli, G.7
-
139
-
-
40749098889
-
Changes in adhesive and migratory characteristics of hepatocellular carcinoma (HCC) cells induced by expression of alpha3beta1 integrin
-
DOI 10.1016/j.bbagen.2007.09.007, PII S0304416507002115
-
Mizuno H, Ogura M, Saito Y, et al: Changes in adhesive and migratory characteristics of hepatocellular carcinoma (HCC) cells induced by expression of alpha3beta1 integrin. Biochim Biophys Acta 1780: 564-570, 2008. (Pubitemid 351381248)
-
(2008)
Biochimica et Biophysica Acta - General Subjects
, vol.1780
, Issue.3
, pp. 564-570
-
-
Mizuno, H.1
Ogura, M.2
Saito, Y.3
Sekine, W.4
Sano, R.5
Gotou, T.6
Oku, T.7
Itoh, S.8
Katabami, K.9
Tsuji, T.10
-
140
-
-
0029846756
-
Liver failure and defective hepatocyte regeneration in interleukin-6- deficient mice
-
DOI 10.1126/science.274.5291.1379
-
Cressman DE, Greenbaum LE, De Angelis RA, Ciliberto G, Furth EE, Poli V and Taub R: Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. Science 274: 1379-1383, 1996. (Pubitemid 26391463)
-
(1996)
Science
, vol.274
, Issue.5291
, pp. 1379-1383
-
-
Cressman, D.E.1
Greenbaum, L.E.2
DeAngelis, R.A.3
Ciliberto, G.4
Furth, E.E.5
Poli, V.6
Taub, R.7
-
141
-
-
0032959637
-
Human hepatitis B virus X protein augments the DNA binding of nuclear factor for IL-6 through its basic-leucine zipper domain
-
DOI 10.1002/(SICI)1096-9071(199905)58:1<11::AID-JMV2>3.0.CO;2-H
-
Ohno H, Kaneko S, Lin Y, Kobayashi K and Murakami S: Human hepatitis B virus X protein augments the DNA binding of nuclear factor for IL-6 through its basic-leucine zipper domain. J Med Virol 58: 11-18, 1999. (Pubitemid 29172115)
-
(1999)
Journal of Medical Virology
, vol.58
, Issue.1
, pp. 11-18
-
-
Ohno, H.1
Kaneko, S.2
Lin, Y.3
Kobayashi, K.4
Murakami, S.5
-
142
-
-
0041589356
-
Serum cytokine profiles associated with clinical presentation in Vietnamese infected with hepatitis B virus
-
DOI 10.1016/S1386-6532(02)00271-8, PII S1386653202002718
-
Song IH, Binh VQ, Duy DN, Kun JF, Bock TC, Kremsner PG and Luty AJ: Serum cytokine profiles associated with clinical presentation in Vietnamese infected with hepatitis B virus. J Clin Virol 28: 93-103, 2003. (Pubitemid 36970109)
-
(2003)
Journal of Clinical Virology
, vol.28
, Issue.1
, pp. 93-103
-
-
Song, L.H.1
Binh, V.Q.2
Duy, D.N.3
Kun, J.F.J.4
Bock, T.C.5
Kremsner, P.G.6
Luty, A.J.F.7
-
143
-
-
0031746396
-
Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells
-
Lee Y, Park US, Choi I, Yoon SK, Park YM and Lee YI: Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells. Clin Cancer Res 4: 1711-1717, 1998. (Pubitemid 28304733)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.7
, pp. 1711-1717
-
-
Lee, Y.1
Park, U.-S.2
Choi, I.3
Yoon, S.K.4
Park, Y.M.5
Lee, Y.I.6
-
144
-
-
70349849505
-
Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: An analysis based on gender differences
-
Nakagawa H, Maeda S, Yoshida H, et al: Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: an analysis based on gender differences. Int J Cancer 125: 2264-2269, 2009.
-
(2009)
Int J Cancer
, vol.125
, pp. 2264-2269
-
-
Nakagawa, H.1
Maeda, S.2
Yoshida, H.3
-
145
-
-
0026691627
-
Serum levels of cytokines in chronic liver diseases
-
Tilg H, Wilmer A, Vogel W, Herold M, Nölchen B, Judmaier G and Huber C: Serum levels of cytokines in chronic liver diseases. Gastroenterology 103: 264-274, 1992.
-
(1992)
Gastroenterology
, vol.103
, pp. 264-274
-
-
Tilg, H.1
Wilmer, A.2
Vogel, W.3
Herold, M.4
Nölchen, B.5
Judmaier, G.6
Huber, C.7
-
146
-
-
65649111667
-
High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B
-
Wong VW, Yu J, Cheng AS, Wong GL, Chan HY, Chu ES, Ng EK, Chan FK, Sung JJ and Chan HL: High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B. Int J Cancer 124: 2766-2770, 2009.
-
(2009)
Int J Cancer
, vol.124
, pp. 2766-2770
-
-
Wong, V.W.1
Yu, J.2
Cheng, A.S.3
Wong, G.L.4
Chan, H.Y.5
Chu, E.S.6
Ng, E.K.7
Chan, F.K.8
Sung, J.J.9
Chan, H.L.10
-
147
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu H, Pardoll D and Jove R: STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 9: 798-809, 2009.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
148
-
-
77950349016
-
Th17 and regulatory T cells in mediating and restraining inflammation
-
Littman DR and Rudensky AY: Th17 and regulatory T cells in mediating and restraining inflammation. Cell 140: 845-858, 2010.
-
(2010)
Cell
, vol.140
, pp. 845-858
-
-
Littman, D.R.1
Rudensky, A.Y.2
-
149
-
-
34447327216
-
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
-
DOI 10.1126/science.1140485
-
Naugler WE, Sakurai T, Kim S, Maeda S, Kim K, Elsharkawy AM and Karin M: Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317: 121-124, 2007. (Pubitemid 47056470)
-
(2007)
Science
, vol.317
, Issue.5834
, pp. 121-124
-
-
Naugler, W.E.1
Sakurai, T.2
Kim, S.3
Maeda, S.4
Kim, K.5
Elsharkawy, A.M.6
Karin, M.7
-
150
-
-
74549167737
-
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
-
Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, Osterreicher CH, Takahashi H and Karin M: Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 140: 197-208, 2010.
-
(2010)
Cell
, vol.140
, pp. 197-208
-
-
Park, E.J.1
Lee, J.H.2
Yu, G.Y.3
He, G.4
Ali, S.R.5
Holzer, R.G.6
Osterreicher, C.H.7
Takahashi, H.8
Karin, M.9
-
151
-
-
0031811737
-
Effect of IL-6 overexpression on the metastatic potential of rat hepatocellular carcinoma cells
-
DOI 10.1007/BF02303786
-
Reichner JS, Mulligan JA, Spisni R, Sotomayor EA, Albina JE and Bland KI: Effect of IL-6 overexpression on the metastatic potential of rat hepatocellular carcinoma cells. Ann Surg Oncol 5: 279-286, 1998. (Pubitemid 28249321)
-
(1998)
Annals of Surgical Oncology
, vol.5
, Issue.3
, pp. 279-286
-
-
Reichner, J.S.1
Mulligan, J.A.2
Spisni, R.3
Sotomayor, E.A.4
Albina, J.E.5
Bland, K.I.6
-
152
-
-
3042575159
-
Serum hepatocyte growth factor and interleukin-6 levels can distinguish patients with primary or metastatic liver tumors from those with benign liver lesions
-
Coskun U, Bukan N, Sancak B, Gunel N, Ozenirler S, Unal A and Yucel A: Serum hepatocyte growth factor and interleukin-6 levels can distinguish patients with primary or metastatic liver tumors from those with benign liver lesions. Neoplasma 51: 209-213, 2004. (Pubitemid 38821501)
-
(2004)
Neoplasma
, vol.51
, Issue.3
, pp. 209-213
-
-
Coskun, U.1
Bukan, N.2
Sancak, B.3
Gunel, N.4
Ozenirler, S.5
Unal, A.6
Yucel, A.7
-
153
-
-
0037256512
-
Cytokine gene polymorphisms in patients infected with hepatitis B virus
-
DOI 10.1111/j.1572-0241.2003.07179.x, PII S0002927002058471
-
Ben Ari Z, Mor E, Papo O, Kfir B, Sulkes J, Tambur AR, Tur-Kaspa R and Klein T: Cytokine gene polymorphisms in patients infected with hepatitis B virus. Am J Gastroenterol 98: 144-150, 2003. (Pubitemid 36135183)
-
(2003)
American Journal of Gastroenterology
, vol.98
, Issue.1
, pp. 144-150
-
-
Ben-Ari, Z.1
Mor, E.2
Papo, O.3
Kfir, B.4
Sulkes, J.5
Tambur, A.R.6
Tur-Kaspa, R.7
Klein, T.8
-
154
-
-
79952523091
-
IL-6-174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma
-
Giannitrapani L, Soresi M, Giacalone A, Campagna ME, Marasà M, Cervello M, Marasà S and Montalto G: IL-6-174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma. OMICS 15: 183-186, 2011.
-
(2011)
OMICS
, vol.15
, pp. 183-186
-
-
Giannitrapani, L.1
Soresi, M.2
Giacalone, A.3
Campagna, M.E.4
Marasà, M.5
Cervello, M.6
Marasà, S.7
Montalto, G.8
-
155
-
-
0038147057
-
Association between interleukin 6 promoter variants and chronic hepatitis B progression
-
Park BL, Lee HS, Kim YJ, Kim JY, Jung JH, Kim LH and Shin HD: Association between interleukin 6 promoter variants and chronic hepatitis B progression. Exp Mol Med 35: 76-82, 2003. (Pubitemid 36626937)
-
(2003)
Experimental and Molecular Medicine
, vol.35
, Issue.2
, pp. 76-82
-
-
Park, B.L.1
Lee, H.-S.2
Kim, Y.J.3
Kim, J.Y.4
Jung, J.H.5
Kim, L.H.6
Shin, H.D.7
-
157
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M: Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436, 2006.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
158
-
-
17044417550
-
TNF-alfa induced DNA damage in primary murine hepatocytes
-
Wheelhouse NM, Chan YS, Gillies SE, Caldwell H, Ross JA, Harrison DJ and Prost S: TNF-alfa induced DNA damage in primary murine hepatocytes. Int J Mol Med 12: 889-894, 2003.
-
(2003)
Int J Mol Med
, vol.12
, pp. 889-894
-
-
Wheelhouse, N.M.1
Chan, Y.S.2
Gillies, S.E.3
Caldwell, H.4
Ross, J.A.5
Harrison, D.J.6
Prost, S.7
-
159
-
-
21444450865
-
Expression of TNF-related apoptosis-inducing ligand in human hepatocellular carcinoma
-
Shiraki K, Yamanaka T, Inoue H, Kawakita T, Enokimura N, Okano H, Sugimoto K, Murata K and Nakano T: Expression of TNF-related apoptosis-inducing ligand in human hepatocellular carcinoma. Int J Oncol 26: 1273-1281, 2005.
-
(2005)
Int J Oncol
, vol.26
, pp. 1273-1281
-
-
Shiraki, K.1
Yamanaka, T.2
Inoue, H.3
Kawakita, T.4
Enokimura, N.5
Okano, H.6
Sugimoto, K.7
Murata, K.8
Nakano, T.9
-
160
-
-
0033063046
-
Serum levels of cytokines in hepatitis C-related liver disease: A longitudinal study
-
Huang YS, Hwang SJ, Chan CY, Wu JC, Chao Y, Chang FY and Lee SD: Serum levels of cytokines in hepatitis C-related liver disease: a longitudinal study. Zhonghua Yi Xue Za Zhi (Taipei) 62: 327-333, 1999. (Pubitemid 29289363)
-
(1999)
Chinese Medical Journal (Taipei)
, vol.62
, Issue.6
, pp. 327-333
-
-
Huang, Y.-S.1
Hwang, S.-J.2
Chan, C.-Y.3
Wu, J.-C.4
Chao, Y.5
Chang, F.-Y.6
Lee, S.-D.7
-
161
-
-
0026770647
-
Preoperative and postoperative cytokines in patients with cancer
-
Nakazaki H: Preoperative and postoperative cytokines in patients with cancer. Cancer 70: 709-713, 1992.
-
(1992)
Cancer
, vol.70
, pp. 709-713
-
-
Nakazaki, H.1
-
162
-
-
0030770259
-
Serum levels of IL-10, IL-15 and soluble tumour necrosis factor-alpha (TNF-alpha) receptors in type C chronic liver disease
-
Kakumu S, Okumura A, Ishikawa T, Yano M, Enomoto A, Nishimura H, Yoshioka K and Yoshika Y: Serum levels of IL-10, IL-15 and soluble tumor necrosis factor-alfa (TNF-alfa) receptors in type C chronic liver disease. Clin Exp Immunol 109: 458-463, 1997. (Pubitemid 27402313)
-
(1997)
Clinical and Experimental Immunology
, vol.109
, Issue.3
, pp. 458-463
-
-
Kakumu, S.1
Okumura, A.2
Ishikawa, T.3
Yano, M.4
Enomoto, A.5
Nishimura, H.6
Yoshioka, K.7
Yoshikai, Y.8
-
163
-
-
12244250729
-
Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer
-
DOI 10.1016/S1590-8658(02)80073-1
-
Bortolami M, Venturi C, Giacomelli L, Scalerta R, Bacchetti S, Marino F, Floreani A, Lise M, Naccarato R and Farinati F: Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer. Dig Liver Dis 34: 794-801, 2002. (Pubitemid 36097519)
-
(2002)
Digestive and Liver Disease
, vol.34
, Issue.11
, pp. 794-801
-
-
Bortolami, M.1
Venturi, C.2
Giacomelli, L.3
Scalerta, R.4
Bacchetti, S.5
Marino, F.6
Floreani, A.7
Lise, M.8
Naccarato, R.9
Farinati, F.10
-
164
-
-
30444448077
-
Cytokine profile in Egyptian hepatitis C virus genotype-4 in relation to liver disease progression
-
Zekri AR, Ashour MS, Hassan A, Alam El-Din HM, El Shehaby AM and Abu-Shady MA: Cytokine profile in Egyptian hepatitis C virus genotype-4 in relation to liver disease progression. World J Gastroenterol 11: 6624-6630, 2005. (Pubitemid 43072701)
-
(2005)
World Journal of Gastroenterology
, vol.11
, Issue.42
, pp. 6624-6630
-
-
Zekri, A.-R.N.1
El-din, A.M.S.2
Hassan, A.3
El-Din, H.M.A.4
El-Shehaby, A.M.R.5
Abu-Shady, M.A.6
-
165
-
-
4043102715
-
Increased risk of developing hepatocellular carcinoma associated with carriage of the TNF2 allele of the -308 tumor necrosis factor-alpha promoter gene
-
DOI 10.1023/B:CACO.0000036173.99930.75
-
Ho SY, Wang YJ, Chen HL, Chen CH, Chang CJ, Wang PJ, Chen HH and Guo HR: Increased risk of developing hepatocellular carcinoma associated with carriage of the TNF2 allele of the -308 tumor necrosis factor-β promoter gene. Cancer Causes Control 15: 657-663, 2004. (Pubitemid 39060927)
-
(2004)
Cancer Causes and Control
, vol.15
, Issue.7
, pp. 657-663
-
-
Ho, S.-Y.1
Wang, Y.-J.2
Chen, H.-L.3
Chen, C.-H.4
Chang, C.-J.5
Wang, P.-J.6
Chen, H.H.W.7
Guo, H.-R.8
-
166
-
-
3242713143
-
Frequency and nature of cytokine gene polymorphisms in hepatocellular carcinoma in Hong Kong Chinese
-
Heneghan MA, Johnson PJ, Clare M, Ho S, Harrison PM and Donaldson PT: Frequency and nature of cytokine gene polymorphisms in hepatocellular carcinoma in Hong Kong Chinese. Int J Gastrointest Cancer 34: 19-26, 2003. (Pubitemid 38962757)
-
(2003)
International Journal of Gastrointestinal Cancer
, vol.34
, Issue.1
, pp. 19-26
-
-
Heneghan, M.A.1
Johnson, P.J.2
Clare, M.3
Ho, S.4
Harrison, P.M.5
Donaldson, P.T.6
-
167
-
-
84856173209
-
Tumor necrosis factor-alpha -308G/A polymorphism and risk of hepatocellular carcinoma in hepatitis C virus-infected patients
-
Talaat RM, Esmail AA, Elwakil R, Gurgis AA and Nasr MI: Tumor necrosis factor-alpha -308G/A polymorphism and risk of hepatocellular carcinoma in hepatitis C virus-infected patients. Chin J Cancer 31: 29-35, 2012.
-
(2012)
Chin J Cancer
, vol.31
, pp. 29-35
-
-
Talaat, R.M.1
Esmail, A.A.2
Elwakil, R.3
Gurgis, A.A.4
Nasr, M.I.5
-
168
-
-
32944464648
-
Pathogen recognition and innate immunity
-
DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
-
Akira S, Uematsu S and Takeuchi O: Pathogen recognition and innate immunity. Cell 124: 783-801, 2006. (Pubitemid 43261452)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
169
-
-
1042289741
-
Essential Role of Matrix Metalloproteinases in Interleukin-1-induced Myofibroblastic Activation of Hepatic Stellate Cell in Collagen
-
DOI 10.1074/jbc.M310999200
-
Han YP, Zhou L, Wang J, Xiong S, Garner WL, French SW and Tsukamoto H: Essential role of matrix metalloproteinases in interleukin-1-induced myofibroblastic activation of hepatic stellate cell in collagen. J Biol Chem 279: 4820-4828, 2004. (Pubitemid 38199077)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4820-4828
-
-
Han, Y.-P.1
Zhou, L.2
Wang, J.3
Xiong, S.4
Garner, W.L.5
French, S.W.6
Tsukamoto, H.7
-
170
-
-
33644888000
-
Interleukin-1beta gene polymorphism associated with hepatocellular carcinoma in hepatitis B virus infection
-
Hirankarn N, Kimkong I, Kummee P, Tangkijvanich P and Poovorawan Y: Interleukin-1β gene polymorphism associated with hepatocellular carcinoma in hepatitis B virus infection. World J Gastroenterol 12: 776-779, 2006. (Pubitemid 43380763)
-
(2006)
World Journal of Gastroenterology
, vol.12
, Issue.5
, pp. 776-779
-
-
Hirankarn, N.1
Kimkong, I.2
Kummee, P.3
Tangkijvanich, P.4
Poovorawan, Y.5
-
171
-
-
0037864153
-
Impact of intefieukin- 1beta genetic polymorphisms on the development of hepatitis C virus-related hepatocellular carcinoma in Japan
-
DOI 10.1086/375248
-
Tanaka Y, Furuta T, Suzuki S, Orito E, Yeo AE, Hirashima N, Sugauchi F, Ueda R and Mizokami M: Impact of interleukin-1βgenetic polymorphisms on the development of hepatitis C virusrelated hepatocellular carcinoma in Japan. J Infect Dis 187: 1822-1825, 2003. (Pubitemid 36667895)
-
(2003)
Journal of Infectious Diseases
, vol.187
, Issue.11
, pp. 1822-1825
-
-
Tanaka, Y.1
Furuta, T.2
Suzuki, S.3
Orito, E.4
Yeo, A.E.T.5
Hirashima, N.6
Sugauchi, F.7
Ueda, R.8
Mizokami, M.9
-
172
-
-
0037207461
-
Interleukin-1beta gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection
-
DOI 10.1053/jhep.2003.50017
-
Wang Y, Kato N, Hoshida Y, Yoshida H, Taniguchi H, Goto T, Moriyama M, Otsuka M, Shiina S, Shiratori Y, Ito Y and Omata M: Interleukin-1β gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection. Hepatology 37: 65-71, 2003. (Pubitemid 36042146)
-
(2003)
Hepatology
, vol.37
, Issue.1
, pp. 65-71
-
-
Wang, Y.1
Kato, N.2
Hoshida, Y.3
Yoshida, H.4
Taniguchi, H.5
Goto, T.6
Moriyama, M.7
Otsuka, M.8
Shiina, S.9
Shiratori, Y.10
Ito, Y.11
Omata, M.12
-
173
-
-
0141540375
-
Serum levels of interleukin- 10, interleukin-12 and soluble interleukin-2 receptor in chronic liver disease type C
-
Kitaoka S, Shiota G and Kawasaki H: Serum levels of interleukin-10, interleukin-12 and soluble interleukin-2 receptor in chronic liver disease type C. Hepatogastroenterology 50: 1569-1574, 2003. (Pubitemid 37186534)
-
(2003)
Hepato-Gastroenterology
, vol.50
, Issue.53
, pp. 1569-1574
-
-
Kitaoka, S.1
Shiota, G.2
Kawasaki, H.3
-
174
-
-
0037015951
-
Expression of interleukin-18, interferon-gamma and interleukin-10 in hepatocellular carcinoma
-
DOI 10.1016/S0165-2478(02)00176-1, PII S0165247802001761
-
Chia CS, Ban K, Ithnin H, Singh H, Krishnan R, Mokhtar S, Malihan N and Seow HF: Expression of interleukin-18, interferongamma and interleukin-10 in hepatocellular carcinoma. Immunol Lett 84: 163-172, 2002. (Pubitemid 35292375)
-
(2002)
Immunology Letters
, vol.84
, Issue.3
, pp. 163-172
-
-
Chia, C.S.1
Ban, K.2
Ithnin, H.3
Singh, H.4
Krishnan, R.5
Mokhtar, S.6
Malihan, N.7
Seow, H.F.8
-
175
-
-
8444243261
-
Increased levels of interleukin-10 in serum from patients with hepatocellular carcinoma correlate with profound numerical deficiencies and immature phenotype of circulating dendritic cell subsets
-
DOI 10.1158/1078-0432.CCR-04-0872
-
Beckebaum S, Zhang X, Chen X, Yu Z, Frilling A, Dworacki G, Grosse-Wilde H, Broelsch CE, Gerken G and Cicinnati VR: Increased levels of interleukin-10 in serum from patients with hepatocellular carcinoma correlate with profound numerical deficiencies and immature phenotype of circulating dendritic cell subsets. Clin Cancer Res 10: 7260-7269, 2004. (Pubitemid 39487713)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.21
, pp. 7260-7269
-
-
Beckebaum, S.1
Zhang, X.2
Chen, X.3
Yu, Z.4
Frilling, A.5
Dworacki, G.6
Grosse-Wilde, H.7
Broelsch, C.E.8
Gerken, G.9
Cicinnati, V.R.10
-
176
-
-
0034028927
-
Serum interleukin-10 but not interleukin-6 is related to clinical outcome in patients with resectable hepatocellular carcinoma
-
Chau GY, Wu CW, Lui WY, Chang TJ, Kao HL, Wu LH, King KL, Loong CC, Hsia CY and Chi CW: Serum interleukin-10 but not interleukin-6 is related to clinical outcome in patients with resectable hepatocellular carcinoma. Ann Surg 231: 552-558, 2000.
-
(2000)
Ann Surg
, vol.231
, pp. 552-558
-
-
Chau, G.Y.1
Wu, C.W.2
Lui, W.Y.3
Chang, T.J.4
Kao, H.L.5
Wu, L.H.6
King, K.L.7
Loong, C.C.8
Hsia, C.Y.9
Chi, C.W.10
-
177
-
-
0037447447
-
Interleukin 10 haplotype associated with increased risk of hepatocellular carcinoma
-
DOI 10.1093/hmg/ddg104
-
Shin HD, Park BL, Kim LH, Jung JH, Kim JY, Yoon JH, Kim YJ and Lee HS: Interleukin 10 haplotype associated with increased risk of hepatocellular carcinoma. Hum Mol Genet 12: 901-906, 2003. (Pubitemid 36504032)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.8
, pp. 901-906
-
-
Shin, H.D.1
Park, B.L.2
Kim, L.H.3
Jung, J.H.4
Kim, J.Y.5
Yoon, J.H.6
Kim, Y.J.7
Lee, H.-S.8
-
178
-
-
13444253760
-
Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association
-
DOI 10.1002/cncr.20842
-
Nieters A, Yuan JM, Sun CL, Zhang ZQ, Stoehlmacher J, Govindarajan S and Yu MC: Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association. Cancer 103: 740-748, 2005. (Pubitemid 40216402)
-
(2005)
Cancer
, vol.103
, Issue.4
, pp. 740-748
-
-
Nieters, A.1
Yuan, J.-M.2
Sun, C.-L.3
Zhang, Z.-Q.4
Stoehlmacher, J.5
Govindarajan, S.6
Yu, M.C.7
-
179
-
-
20044377406
-
Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection - Association between TGF-beta1 polymorphisms and hepatocellular carcinoma
-
DOI 10.1016/j.jhep.2004.11.026
-
Migita K, Miyazoe S, Maeda Y, Daikoku M, Abiru S, Ueki T, Yano K, Nagaoka S, Matsumoto T, Nakao K, Hamasaki K, Yatsuhashi H, Ishibashi H and Eguchi K: Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection-association between TGF-β1 polymorphisms and hepatocellular carcinoma. J Hepatol 42: 505-510, 2005. (Pubitemid 40342929)
-
(2005)
Journal of Hepatology
, vol.42
, Issue.4
, pp. 505-510
-
-
Migita, K.1
Miyazoe, S.2
Maeda, Y.3
Daikoku, M.4
Abiru, S.5
Ueki, T.6
Yano, K.7
Nagaoka, S.8
Matsumoto, T.9
Nakao, K.10
Hamasaki, K.11
Yatsuhashi, H.12
Ishibashi, H.13
Eguchi, K.14
-
180
-
-
33747029250
-
Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
-
DOI 10.1016/j.ccr.2006.06.016, PII S1535610806002145
-
Budhu A, Forgues M, Ye QH, He P, Zanetti KA, Kammula US, Chen Y, Qin LX, Tang ZY and Wang XW: Prediction of venous metastases, recurrence and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 10: 99-111, 2006. (Pubitemid 44202603)
-
(2006)
Cancer Cell
, vol.10
, Issue.2
, pp. 99-111
-
-
Budhu, A.1
Forgues, M.2
Ye, Q.-H.3
Jia, H.-L.4
He, P.5
Zanetti, K.A.6
Kammula, U.S.7
Chen, Y.8
Qin, L.-X.9
Tang, Z.-Y.10
Wang, X.W.11
-
181
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri G: Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3: 133-146, 2003.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
182
-
-
0035110705
-
Electroporation-mediated interleukin-12 gene therapy for hepatocellular carcinoma in the mice model
-
Yamashita YI, Shimada M, Hasegawa H, et al: Electroporationmediated interleukin-12 gene therapy for hepatocellular carcinoma in the mice model. Cancer Res 61: 1005-1012, 2001. (Pubitemid 32174418)
-
(2001)
Cancer Research
, vol.61
, Issue.3
, pp. 1005-1012
-
-
Yamashita, Y.-I.1
Shimada, M.2
Hasegawa, H.3
Minagawa, R.4
Rikimaru, T.5
Hamatsu, T.6
Tanaka, S.7
Shirabe, K.8
Miyazaki, J.9
Sugimachi, K.10
-
183
-
-
0030766971
-
Effects of single-dose interleukin-12 exposure on interleukin-12 associated toxicity and interferon-gamma production
-
Leonard JP, Sherman ML, Fisher GL, Buchanan LJ, Larsen G, Atkins MB, Sosman JA, Dutcher JP, Vogelzang NJ and Ryan JL: Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production. Blood 90: 2541-2548, 1997. (Pubitemid 27413462)
-
(1997)
Blood
, vol.90
, Issue.7
, pp. 2541-2548
-
-
Leonard, J.P.1
Sherman, M.L.2
Fisher, G.L.3
Buchanan, L.J.4
Larsen, G.5
Atkins, M.B.6
Sosman, J.A.7
Dutcher, J.P.8
Vogelzang, N.J.9
Ryan, J.L.10
-
184
-
-
2342570309
-
Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors
-
DOI 10.1200/JCO.2004.04.059
-
Sangro B, Mazzolini G, Ruiz J, et al: Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors. J Clin Oncol 22: 1389-1397, 2004. (Pubitemid 41103620)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.8
, pp. 1389-1397
-
-
Sangro, B.1
Mazzolini, G.2
Ruiz, J.3
Herraiz, M.4
Quiroga, J.5
Herrero, I.6
Benito, A.7
Larrache, J.8
Pueyo, J.9
Subtil, J.C.10
Olague, C.11
Sola, J.12
Sadaba, B.13
Lacasa, C.14
Melero, I.15
Qian, C.16
Prieto, J.17
-
185
-
-
67650495415
-
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
-
Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D and Yu H: IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 206: 1457-1464, 2009.
-
(2009)
J Exp Med
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
Yi, T.2
Kortylewski, M.3
Pardoll, D.M.4
Zeng, D.5
Yu, H.6
-
186
-
-
83455162844
-
IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma
-
Gu FM, Li QL, Gao Q, Jiang JH, Zhu K, Huang XY, Pan JF, Yan J, Hu JH, Wang Z, Dai Z, Fan J and Zhou J: IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma. Mol Cancer 10: 150, 2011.
-
(2011)
Mol Cancer
, vol.10
, pp. 150
-
-
Gu, F.M.1
Li, Q.L.2
Gao, Q.3
Jiang, J.H.4
Zhu, K.5
Huang, X.Y.6
Pan, J.F.7
Yan, J.8
Hu, J.H.9
Wang, Z.10
Dai, Z.11
Fan, J.12
Zhou, J.13
-
187
-
-
47549090432
-
TGFbeta in cancer
-
Massague J: TGFbeta in cancer. Cell 134: 215-230, 2008.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
188
-
-
80051768100
-
Molecular pathogenesis of hepatocellular carcinoma: Altering transforming growth factor-β signaling in hepatocarcinogenesis
-
Yamazaki K, Masugi Y and Sakamoto M: Molecular pathogenesis of hepatocellular carcinoma: altering transforming growth factor-β signaling in hepatocarcinogenesis. Dig Dis 29: 284-288, 2011.
-
(2011)
Dig Dis
, vol.29
, pp. 284-288
-
-
Yamazaki, K.1
Masugi, Y.2
Sakamoto, M.3
-
189
-
-
0028959114
-
Transforming growth factor-beta 1 (TGF-beta 1) and TGF-beta 1 receptors in normal, cirrhotic, and neoplastic human livers
-
Bedossa P, Peltier E, Terris B, Franco D and Poynard T: Transforming growth factor-beta 1 (TGF-beta 1) and TGF-beta 1 receptors in normal, cirrhotic, and neoplastic human livers. Hepatology 21: 760-766, 1995.
-
(1995)
Hepatology
, vol.21
, pp. 760-766
-
-
Bedossa, P.1
Peltier, E.2
Terris, B.3
Franco, D.4
Poynard, T.5
-
190
-
-
33748208668
-
C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells
-
DOI 10.1016/j.ccr.2006.07.019, PII S1535610806002479
-
Gomis RR, Alarcon C, Nadal C, van Poznak C and Massague J: C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells. Cancer Cell 10: 203-214, 2006. (Pubitemid 44311064)
-
(2006)
Cancer Cell
, vol.10
, Issue.3
, pp. 203-214
-
-
Gomis, R.R.1
Alarcon, C.2
Nadal, C.3
Van Poznak, C.4
Massague, J.5
-
191
-
-
11344275986
-
Suppression of hepatitis C virus replicon by TGF-beta
-
DOI 10.1016/j.virol.2004.10.036, PII S0042682204007172
-
Murata T, Ohshima T, Yamaji M, Hosaka M, Miyanari Y, Hijikata M and Shimotohno K: Suppression of hepatitis C virus replicon by TGF-β. Virology 331: 407-417, 2005. (Pubitemid 40075466)
-
(2005)
Virology
, vol.331
, Issue.2
, pp. 407-417
-
-
Murata, T.1
Ohshima, T.2
Yamaji, M.3
Hosaka, M.4
Miyanari, Y.5
Hijikata, M.6
Shimotohno, K.7
-
192
-
-
34347232205
-
Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma
-
DOI 10.1002/hep.21672
-
Matsuzaki K, Murata M, Yoshida K, et al: Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma. Hepatology 46: 48-57, 2007. (Pubitemid 47171920)
-
(2007)
Hepatology
, vol.46
, Issue.1
, pp. 48-57
-
-
Matsuzaki, K.1
Murata, M.2
Yoshida, K.3
Sekimoto, G.4
Uemura, Y.5
Sakaida, N.6
Kaibori, M.7
Kamiyama, Y.8
Nishizawa, M.9
Fujisawa, J.10
Okazaki, K.11
Seki, T.12
-
193
-
-
65449159717
-
Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B
-
Murata M, Matsuzaki K, Yoshida K, et al: Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B. Hepatology 49: 1203-1217, 2009.
-
(2009)
Hepatology
, vol.49
, pp. 1203-1217
-
-
Murata, M.1
Matsuzaki, K.2
Yoshida, K.3
-
194
-
-
77951667118
-
Functional switching of TGF-beta1 signalling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter
-
Sohn BH, Park IY, Lee JJ, et al: Functional switching of TGF-beta1 signalling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter. Gastroenterology 138: 1898-1908, 2010.
-
(2010)
Gastroenterology
, vol.138
, pp. 1898-1908
-
-
Sohn, B.H.1
Park, I.Y.2
Lee, J.J.3
-
195
-
-
43949140575
-
Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells
-
DOI 10.1002/hep.22201
-
Fransvea E, Angelotti U, Antonaci S and Giannelli G: Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells. Hepatology 47: 1557-1566, 2008. (Pubitemid 351702739)
-
(2008)
Hepatology
, vol.47
, Issue.5
, pp. 1557-1566
-
-
Fransvea, E.1
Angelotti, U.2
Antonaci, S.3
Giannelli, G.4
-
196
-
-
0036317838
-
Transforming growth factor-beta1 triggers hepatocellular carcinoma invasiveness via alpha3beta1 integrin
-
Giannelli G, Fransvea E, Marinosci F, Bergamini C, Colucci S, Schiraldi O and Antonaci S: Transforming growth factor-beta1 triggers hepatocellular carcinoma invasiveness via alpha3beta1 integrin. Am J Pathol 161: 183-193, 2002. (Pubitemid 34760784)
-
(2002)
American Journal of Pathology
, vol.161
, Issue.1
, pp. 183-193
-
-
Giannelli, G.1
Fransvea, E.2
Marinosci, F.3
Bergamini, C.4
Colucci, S.5
Schiraldi, O.6
Antonaci, S.7
-
197
-
-
32544447712
-
Transforming growth factor-beta1 upregulates transcription of alpha3 integrin gene in hepatocellular carcinoma cells via Ets-transcription factor-binding motif in the promoter region
-
DOI 10.1007/s10585-005-5260-x
-
Katabami K, Mizuno H, Sano R, Saito Y, Ogura M, Itoh S and Tsuji T: Transforming growth factor-beta1 upregulates transcription of alpha3 integrin gene in hepatocellular carcinoma cells via Ets-transcription factor-binding motif in the promoter region. Clin Exp Metastasis 22: 539-548, 2005. (Pubitemid 43234638)
-
(2005)
Clinical and Experimental Metastasis
, vol.22
, Issue.7
, pp. 539-548
-
-
Katabami, K.1
Mizuno, H.2
Sano, R.3
Saito, Y.4
Ogura, M.5
Itoh, S.6
Tsuji, T.7
-
198
-
-
70350059078
-
Inhibition of transforming growth factor beta receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation
-
Mazzocca A, Fransvea E, Lavezzari G, Antonaci S and Giannelli G: Inhibition of transforming growth factor beta receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation. Hepatology 50: 1140-1151, 2009.
-
(2009)
Hepatology
, vol.50
, pp. 1140-1151
-
-
Mazzocca, A.1
Fransvea, E.2
Lavezzari, G.3
Antonaci, S.4
Giannelli, G.5
-
199
-
-
75449092617
-
Downregulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross talk and tumor progression in hepatocellular carcinoma
-
Mazzocca A, Fransvea E, Dituri F, Lupo L, Antonaci S and Giannelli G: Downregulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross talk and tumor progression in hepatocellular carcinoma. Hepatology 51: 523-534, 2010.
-
(2010)
Hepatology
, vol.51
, pp. 523-534
-
-
Mazzocca, A.1
Fransvea, E.2
Dituri, F.3
Lupo, L.4
Antonaci, S.5
Giannelli, G.6
-
200
-
-
0038756636
-
Transforming growth factor beta-1 induces Snail transcription factor in epithelial cell lines. Mechanisms for epithelial mesenchymal transitions
-
DOI 10.1074/jbc.M211304200
-
Peinado H, Quintanilla M and Cano A: Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem 278: 21113-21123, 2003. (Pubitemid 36806424)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.23
, pp. 21113-21123
-
-
Peinado, H.1
Quintanilla, M.2
Cano, A.3
-
201
-
-
70449636444
-
Hepatic tumorstroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
-
Van Zijl F, Mair M, Csiszar A, Schneller D, Zulehner G, Huber H, Eferl R, Beug H, Dolznig H and Mikulits W: Hepatic tumorstroma crosstalk guides epithelial to mesenchymal transition at the tumor edge. Oncogene 28: 4022-4033, 2009.
-
(2009)
Oncogene
, vol.28
, pp. 4022-4033
-
-
Van Zijl, F.1
Mair, M.2
Csiszar, A.3
Schneller, D.4
Zulehner, G.5
Huber, H.6
Eferl, R.7
Beug, H.8
Dolznig, H.9
Mikulits, W.10
-
202
-
-
77950095763
-
TGFbeta mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
-
Wang B, Hsu SH, Majumder S, Kutay H, Huang W, Jacob ST and Ghoshal K: TGFbeta mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene 29: 1787-1797, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 1787-1797
-
-
Wang, B.1
Hsu, S.H.2
Majumder, S.3
Kutay, H.4
Huang, W.5
Jacob, S.T.6
Ghoshal, K.7
-
203
-
-
47049125858
-
Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells
-
DOI 10.1002/ijc.23580
-
Huang S, He X, Ding J, Liang L, Zhao Y, Zhang Z, Yao X, Pan Z, Zhang P, Li J, Wan D and Gu J: Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells. Int J Cancer 123: 972-978, 2008. (Pubitemid 352032429)
-
(2008)
International Journal of Cancer
, vol.123
, Issue.4
, pp. 972-978
-
-
Huang, S.1
He, X.2
Ding, J.3
Liang, L.4
Zhao, Y.5
Zhang, Z.6
Yao, X.7
Pan, Z.8
Zhang, P.9
Li, J.10
Wan, D.11
Gu, J.12
-
204
-
-
1542709590
-
Possible contribution of circulating transforming growth factor-beta1 to immunity and prognosis in unresectable hepatocellular carcinoma
-
Okumoto K, Hattori E, Tamura K, Kiso S, Watanabe H, Saito K, Saito T, Togashi H and Kawata S: Possible contribution of circulating transforming growth factor-β1 to immunity and prognosis in unresectable hepatocellular carcinoma. Liver Int 24: 21-28, 2004. (Pubitemid 38351210)
-
(2004)
Liver International
, vol.24
, Issue.1
, pp. 21-28
-
-
Okumoto, K.1
Hattori, E.2
Tamura, K.3
Kiso, S.4
Watanabe, H.5
Saito, K.6
Saito, T.7
Togashi, H.8
Kawata, S.9
-
205
-
-
10744219917
-
Association of transforming growth factor-beta1 gene polymorphisms with a hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection
-
Kim YJ, Lee HS, Im JP, Min BH, Kim HD, Jeong JB, Yoon JH, Kim CY, Kim MS, Kim JY, Jung JH, Kim LH, Park BL and Shin HD: Association of transforming growth factor-β1 gene polymorphisms with a hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection. Exp Mol Med 35: 196-202, 2003. (Pubitemid 36841640)
-
(2003)
Experimental and Molecular Medicine
, vol.35
, Issue.3
, pp. 196-202
-
-
Kim, Y.J.1
Lee, H.-S.2
Im, J.P.3
Min, B.-H.4
Kim, H.-D.5
Jeong, J.B.6
Yoon, J.-H.7
Kim, C.Y.8
Kim, M.S.9
Kim, J.Y.10
Jung, J.H.11
Kim, L.H.12
Park, B.L.13
Shin, H.D.14
-
206
-
-
77953596327
-
Putative association of transforming growth factor-alpha polymorphisms with clearance of hepatitis B virus and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B virus infection
-
Kim YJ, Kim HY, Kim JS, Lee JH, Yoon JH, Kim CY, Park BL, Cheong HS, Bae JS, Kim S, Shin HD and Lee HS: Putative association of transforming growth factor-alpha polymorphisms with clearance of hepatitis B virus and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B virus infection. J Viral Hepat 17: 518-526, 2010.
-
(2010)
J Viral Hepat
, vol.17
, pp. 518-526
-
-
Kim, Y.J.1
Kim, H.Y.2
Kim, J.S.3
Lee, J.H.4
Yoon, J.H.5
Kim, C.Y.6
Park, B.L.7
Cheong, H.S.8
Bae, J.S.9
Kim, S.10
Shin, H.D.11
Lee, H.S.12
-
207
-
-
84860672829
-
Association between transforming growth factor-β1 polymorphisms and hepatocellular cancer risk: A meta-analysis
-
doi: 10.1111/j.1872-034X.2011.00958.x [Epub ahead of print]
-
Xiang TX, Cheng N, Li XN and Wu XP: Association between transforming growth factor-β1 polymorphisms and hepatocellular cancer risk: a meta-analysis. Hepatol Res doi: 10.1111/j.1872-034X.2011.00958.x [Epub ahead of print] 2012.
-
(2012)
Hepatol Res
-
-
Xiang, T.X.1
Cheng, N.2
Li, X.N.3
Wu, X.P.4
-
208
-
-
43749088730
-
Wound repair and regeneration
-
DOI 10.1038/nature07039, PII NATURE07039
-
Gurtner GC, Werner S, Barrandon Y and Longaker MT: Wound repair and regeneration. Nature 453: 314-321, 2008. (Pubitemid 351693137)
-
(2008)
Nature
, vol.453
, Issue.7193
, pp. 314-321
-
-
Gurtner, G.C.1
Werner, S.2
Barrandon, Y.3
Longaker, M.T.4
-
209
-
-
18144364350
-
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis
-
DOI 10.1016/j.cytogfr.2005.01.004
-
Presta M, Dell'Era P, Mitola S, Moroni E, Ronca R and Rusnati M: Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev 16: 159-178, 2005. (Pubitemid 40616114)
-
(2005)
Cytokine and Growth Factor Reviews
, vol.16
, Issue.2 SPEC. ISS.
, pp. 159-178
-
-
Presta, M.1
Dell'Era, P.2
Mitola, S.3
Moroni, E.4
Ronca, R.5
Rusnati, M.6
-
210
-
-
56949101730
-
Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention
-
Ho HK, Pok S, Streit S, Ruhe JE, Hart S, Lim KS, Loo HL, Aung MO, Lim SG and Ullrich A: Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention. J Hepatol 50: 118-127, 2009.
-
(2009)
J Hepatol
, vol.50
, pp. 118-127
-
-
Ho, H.K.1
Pok, S.2
Streit, S.3
Ruhe, J.E.4
Hart, S.5
Lim, K.S.6
Loo, H.L.7
Aung, M.O.8
Lim, S.G.9
Ullrich, A.10
-
211
-
-
77749304065
-
Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth
-
Amann T, Bataille F, Spruss T, et al: Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth. Am J Pathol 176: 1433-1442, 2010.
-
(2010)
Am J Pathol
, vol.176
, pp. 1433-1442
-
-
Amann, T.1
Bataille, F.2
Spruss, T.3
-
212
-
-
0027954225
-
c-met mRNA overexpression in human hepatocellular carcinoma
-
DOI 10.1016/0270-9139(94)90057-4
-
Boix L, Rosa JL, Ventura F, Castells A, Bruix J, Rodés J and Bartrons R: c-MET mRNA overexpression in human hepatocellular carcinoma. Hepatology 19: 88-91, 1994. (Pubitemid 24020476)
-
(1994)
Hepatology
, vol.19
, Issue.1
, pp. 88-91
-
-
Boix, L.1
Rosa, J.L.2
Ventura, F.3
Castells, A.4
Bruix, J.5
Rodes, J.6
Bartrons, R.7
-
213
-
-
0030857813
-
Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth factor/c-met, TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas
-
Kiss A, Wang NJ, Xie JP and Thorgeirsson SS: Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth factor/c-met, TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas. Clin Cancer Res 3: 1059-1066, 1997. (Pubitemid 27319751)
-
(1997)
Clinical Cancer Research
, vol.3
, Issue.7
, pp. 1059-1066
-
-
Kiss, A.1
Wang, N.-J.2
Xie, J.-P.3
Thorgeirsson, S.S.4
-
214
-
-
0033867263
-
u-PA and c-MET mRNA expression is co-ordinately enhanced while hepatocyte growth factor mRNA is down-regulated in human hepatocellular carcinoma
-
DOI 10.1002/1097-0215(20000901)87:5<644::AID-IJC4>3.0.CO;2-W
-
Tavian D, De PG, Benetti A, Portolani N, Giulini SM and Barlati S: u-PA and c-MET mRNA expression is co-ordinately enhanced while hepatocyte growth factor mRNA is down-regulated in human hepatocellular carcinoma. Int J Cancer 87: 644-649, 2000. (Pubitemid 30620405)
-
(2000)
International Journal of Cancer
, vol.87
, Issue.5
, pp. 644-649
-
-
Tavian, D.1
De Petro, G.2
Benetti, A.3
Portolani, N.4
Giulini, S.M.5
Barlati, S.6
-
215
-
-
0030951358
-
Expression of hepatocyte growth factor and its receptor, the c-met proto-oncogene, in hepatocellular carcinoma
-
DOI 10.1002/hep.510250321
-
Ueki T, Fujimoto J, Suzuki T, Yamamoto H and Okamoto E: Expression of hepatocyte growth factor and its receptor, the c-met proto-oncogene, in hepatocellular carcinoma. Hepatology 25: 619-623, 1997. (Pubitemid 27106443)
-
(1997)
Hepatology
, vol.25
, Issue.3
, pp. 619-623
-
-
Ueki, T.1
Fujimoto, J.2
Suzuki, T.3
Yamamoto, H.4
Okamoto, E.5
-
216
-
-
33745220780
-
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
-
Kaposi-Novak P, Lee JS, Gomez-Quiroz L, Coulouarn C, Factor VM and Thorgeirsson SS: Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. J Clin Invest 116: 1582-1595, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 1582-1595
-
-
Kaposi-Novak, P.1
Lee, J.S.2
Gomez-Quiroz, L.3
Coulouarn, C.4
Factor, V.M.5
Thorgeirsson, S.S.6
-
217
-
-
0030639167
-
Control of angiogenesis by the pericyte: Molecular mechanisms and significance
-
Hirschi KK and D'Amore PA: Control of angiogenesis by the pericyte: molecular mechanisms and significance. EXS 79: 419-428, 1997.
-
(1997)
EXS
, vol.79
, pp. 419-428
-
-
Hirschi, K.K.1
D'Amore, P.A.2
-
218
-
-
7244250405
-
Angiogenesis and hepatocellular carcinoma
-
DOI 10.1016/j.jhep.2004.09.006, PII S0168827804003940
-
Semela D and Dufour JF: Angiogenesis and hepatocellular carcinoma. J Hepatol 41: 864-880, 2004. (Pubitemid 39434320)
-
(2004)
Journal of Hepatology
, vol.41
, Issue.5
, pp. 864-880
-
-
Semela, D.1
Dufour, J.-F.2
-
219
-
-
33745547361
-
New therapies for hepatocellular carcinoma
-
DOI 10.1038/sj.onc.1209550, PII 1209550
-
Avila MA, Berasain C, Sangro B and Prieto J: New therapies for hepatocellular carcinoma. Oncogene 25: 3866-3884, 2006. (Pubitemid 43980482)
-
(2006)
Oncogene
, vol.25
, Issue.27
, pp. 3866-3884
-
-
Avila, M.A.1
Berasain, C.2
Sangro, B.3
Prieto, J.4
-
220
-
-
34447537888
-
Prognostic significance of HIF-2alpha/EPAS1 expression in hepatocellular carcinoma
-
Bangoura G, Liu ZS, Qian Q, Jiang CQ, Yang GF and Jing S: Prognostic significance of HIF-2alpha/EPAS1 expression in hepatocellular carcinoma. World J Gastroenterol 13: 3176-3182, 2007. (Pubitemid 47064579)
-
(2007)
World Journal of Gastroenterology
, vol.13
, Issue.23
, pp. 3176-3182
-
-
Bangoura, G.1
Liu, Z.-S.2
Qian, Q.3
Jiang, C.-Q.4
Yang, G.-F.5
Jing, S.6
-
221
-
-
77952163228
-
The role of NFkappaB in Hepatitis b virus X proteinmediated upregulation of VEGF and MMPs
-
Liu LP, Liang HF, Chen XP, Zhang WG, Yang SL, Xu T and Ren L: The role of NFkappaB in Hepatitis b virus X proteinmediated upregulation of VEGF and MMPs. Cancer Invest 28: 443-451, 2010.
-
(2010)
Cancer Invest
, vol.28
, pp. 443-451
-
-
Liu, L.P.1
Liang, H.F.2
Chen, X.P.3
Zhang, W.G.4
Yang, S.L.5
Xu, T.6
Ren, L.7
-
222
-
-
68949091981
-
Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis
-
Yang JC, Teng CF, Wu HC, Tsai HW, Chuang HC, Tsai TF, Hsu YH, Huang W, Wu LW and Su IJ: Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis. Hepatology 49: 1962-1971, 2009.
-
(2009)
Hepatology
, vol.49
, pp. 1962-1971
-
-
Yang, J.C.1
Teng, C.F.2
Wu, H.C.3
Tsai, H.W.4
Chuang, H.C.5
Tsai, T.F.6
Hsu, Y.H.7
Huang, W.8
Wu, L.W.9
Su, I.J.10
-
223
-
-
0036254553
-
Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: A comparison with angiopoietin/Tie pathway
-
Dhar DK, Naora H, Yamanoi A, Ono T, Kohno H and Otani H: Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: a comparison with angiopoietin/Tie pathway. Anticancer Res 22: 379-386, 2002. (Pubitemid 34475326)
-
(2002)
Anticancer Research
, vol.22
, Issue.1 A
, pp. 379-386
-
-
Dhar, D.K.1
Naora, H.2
Yamanoi, A.3
Ono, T.4
Kohno, H.5
Otani, H.6
Nagasue, N.7
-
224
-
-
0035190559
-
Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma
-
DOI 10.1309/FXNL-QTN1-94FH-AB3A
-
Ng IO, Poon RT, Lee JM, Fan ST, Ng M and Tso WK: Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma. Am J Clin Pathol 116: 838-845, 2001. (Pubitemid 33108154)
-
(2001)
American Journal of Clinical Pathology
, vol.116
, Issue.6
, pp. 838-845
-
-
Ng, I.O.L.1
Poon, R.T.P.2
Lee, J.M.F.3
Fan, S.T.4
Ng, M.5
Tso, W.K.6
-
225
-
-
4944234987
-
Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma
-
DOI 10.1002/bjs.4594
-
Poon RT, Ho JW, Tong CS, Lau C, Ng IO and Fan ST: Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma. Br J Surg 91: 1354-1360, 2004. (Pubitemid 39331462)
-
(2004)
British Journal of Surgery
, vol.91
, Issue.10
, pp. 1354-1360
-
-
Poon, R.T.P.1
Ho, J.W.Y.2
Tong, C.S.W.3
Lau, C.4
Ng, I.O.L.5
Fan, S.-T.6
-
226
-
-
0033918376
-
Detection of vascular endothelial growth factor and its receptor expression in human hepatocellular carcinoma biopsy specimens
-
DOI 10.1046/j.1440-1746.2000.02201.x
-
Shimamura T, Saito S, Morita K, Kitamura T, Morimoto M, Kiba T, Numata K, Tanaka K and Sekihara H: Detection of vascular endothelial growth factor and its receptor expression in human hepatocellular carcinoma biopsy specimens. J Gastroenterol Hepatol 15: 640-646, 2000. (Pubitemid 30435715)
-
(2000)
Journal of Gastroenterology and Hepatology
, vol.15
, Issue.6
, pp. 640-646
-
-
Shimamura, T.1
Saito, S.2
Morita, K.3
Kitamura, T.4
Morimoto, M.5
Kiba, T.6
Numata, K.7
Tanaka, K.8
Sekihara, H.9
-
227
-
-
34250372946
-
Hepatitis B x antigen up-regulates vascular endothelial growth factor receptor 3 in hepatocarcinogenesis
-
DOI 10.1002/hep.21610
-
Lian Z, Liu J, Wu M, Wang HY, Arbuthnot P, Kew M and Feitelson MA: Hepatitis B x antigen up-regulates vascular endothelial growth factor receptor 3 in hepatocarcinogenesis. Hepatology 45: 1390-1399, 2007. (Pubitemid 46918323)
-
(2007)
Hepatology
, vol.45
, Issue.6
, pp. 1390-1399
-
-
Lian, Z.1
Liu, J.2
Wu, M.3
Wang, H.-Y.4
Arbuthnot, P.5
Kew, M.6
Feitelson, M.A.7
-
228
-
-
0031807538
-
Expression of vascular endothelial growth factor in human hepatocellular carcinoma
-
DOI 10.1002/hep.510280111
-
Yamaguchi R, Yano H, Iemura A, Ogasawara S, Haramaki M and Kojiro M: Expression of vascular endothelial growth factor in human hepatocellular carcinoma. Hepatology 28: 68-77, 1998. (Pubitemid 28299987)
-
(1998)
Hepatology
, vol.28
, Issue.1
, pp. 68-77
-
-
Yamaguchi, R.1
Yano, H.2
Iemura, A.3
Ogasawara, S.4
Haramaki, M.5
Kojiro, M.6
-
229
-
-
7244222908
-
High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: A prospective study
-
Poon RT, Lau C, Yu WC, Fan ST and Wong J: High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: a prospective study. Oncol Rep 11: 1077-1084, 2004.
-
(2004)
Oncol Rep
, vol.11
, pp. 1077-1084
-
-
Poon, R.T.1
Lau, C.2
Yu, W.C.3
Fan, S.T.4
Wong, J.5
-
230
-
-
0043163428
-
Prognostic significance of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin in patients with resectable hepatocellular carcinoma after surgery
-
DOI 10.1245/ASO.2003.10.002
-
Chao Y, Li CP, Chau GY, Chen CP, King KL, Lui WY, Yen SH, Chang FY, Chan WK and Lee SD: Prognostic significance of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin in patients with resectable hepatocellular carcinoma after surgery. Ann Surg Oncol 10: 355-362, 2003. (Pubitemid 40486931)
-
(2003)
Annals of Surgical Oncology
, vol.10
, Issue.4
, pp. 355-362
-
-
Chao, Y.1
Li, C.-P.2
Chau, G.-Y.3
Chen, C.-P.4
King, K.-L.5
Lui, W.-Y.6
Yen, S.-H.7
Chang, F.-Y.8
Chan, W.-K.9
Lee, S.-D.10
-
231
-
-
0031955570
-
Significance of vascular endothelial growth factor mRNA expression in invasion and metastasis of hepatocellular carcinoma
-
Li XM, Tang ZY, Zhou G, Lui YK and Ye SL: Significance of vascular endothelial growth factor mRNA expression in invasion and metastasis of hepatocellular carcinoma. J Exp Clin Cancer Res 17: 13-17, 1998. (Pubitemid 28215959)
-
(1998)
Journal of Experimental and Clinical Cancer Research
, vol.17
, Issue.1
, pp. 13-17
-
-
Li, X.M.1
Tang, Z.Y.2
Zhou, G.3
Lui, Y.K.4
Ye, S.L.5
-
232
-
-
0033986802
-
Expression of platelet-derived endothelial cell growth factor and vascular endothelial growth factor in hepatocellular carcinoma and portal vein tumor thrombus
-
Zhou J, Tang ZY, Fan J, Wu ZQ, Li XM, Liu YK, Liu F, Sun HC and Ye SL: Expression of platelet-derived endothelial cell growth factor and vascular endothelial growth factor in hepatocellular carcinoma and portal vein tumor thrombus. J Cancer Res Clin Oncol 126: 57-61, 2000. (Pubitemid 30006353)
-
(2000)
Journal of Cancer Research and Clinical Oncology
, vol.126
, Issue.1
, pp. 57-61
-
-
Zhou, J.1
Tang, Z.-Y.2
Fan, J.3
Wu, Z.-Q.4
Li, X.-M.5
Liu, Y.-K.6
Liu, F.7
Sun, H.-C.8
Ye, S.-L.9
-
233
-
-
3543134126
-
Matrix metalloproteinases as modulators of inflammation and innate immunity
-
Parks WC, Wilson CL and Lopez-Boado YS: Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol 4: 617-629, 2004. (Pubitemid 39025047)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.8
, pp. 617-629
-
-
Parks, W.C.1
Wilson, C.L.2
Lopez-Boado, Y.S.3
-
234
-
-
67649445789
-
Uterine cervical carcinoma: Role of matrix metalloproteinases
-
Review
-
Libra M, Scalisi A, Vella N, Clementi S, Sorio R, Stivala F, Spandidos DA and Mazzarino C: Uterine cervical carcinoma: role of matrix metalloproteinases (Review). Int J Oncol 34: 897-903, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 897-903
-
-
Libra, M.1
Scalisi, A.2
Vella, N.3
Clementi, S.4
Sorio, R.5
Stivala, F.6
Spandidos, D.A.7
Mazzarino, C.8
-
235
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock K, Plaks V and Werb Z: Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141: 52-67, 2010.
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
236
-
-
77956301181
-
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion
-
Bourboulia D and Stetler-Stevenson WG: Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): positive and negative regulators in tumor cell adhesion. Semin Cancer Biol 20: 161-168, 2010.
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 161-168
-
-
Bourboulia, D.1
Stetler-Stevenson, W.G.2
-
237
-
-
33846948601
-
The hepatitis B virus X protein promotes hepatocellular carcinoma metastasis by upregulation of matrix metalloproteinases
-
Ou DP, Tao YM, Tang FQ and Yang LY: The hepatitis B virus X protein promotes hepatocellular carcinoma metastasis by upregulation of matrix metalloproteinases. Int J Cancer 120: 1208-1214, 2007.
-
(2007)
Int J Cancer
, vol.120
, pp. 1208-1214
-
-
Ou, D.P.1
Tao, Y.M.2
Tang, F.Q.3
Yang, L.Y.4
-
238
-
-
14844307045
-
Hepatitis B virus X protein promotes cell migration by inducing matrix metalloproteinase-3
-
Yu FL, Liu HJ, Lee JW, Liao MH and Shih WL: Hepatitis B virus X protein promotes cell migration by inducing matrix metalloproteinase-3. J Hepatol 42: 520-527, 2005.
-
(2005)
J Hepatol
, vol.42
, pp. 520-527
-
-
Yu, F.L.1
Liu, H.J.2
Lee, J.W.3
Liao, M.H.4
Shih, W.L.5
-
239
-
-
0036955336
-
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression
-
DOI 10.1172/JCI200215887
-
Lara-Pezzi E, Gómez-Gaviro MV, Gálvez BG, Mira E, Iñiguez MA, Fresno M, Martínez-A C, Arroyo AG and López-Cabrera M: The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. J Clin Invest 110: 1831-1838, 2002. (Pubitemid 36076490)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.12
, pp. 1831-1838
-
-
Lara-Pezzi, E.1
Victoria G.-Gaviro, M.2
Galvez, B.G.3
Mira, E.4
Iniguez, M.A.5
Fresno, M.6
Carlos, M.-A.7
Arroyo, A.G.8
Lopez-Cabrera, M.9
-
240
-
-
79953325124
-
Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator twist1
-
Zhao XL, Sun T, Che N, Sun D, Zhao N, Dong XY, Gu Q, Yao Z and Sun BC: Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator twist1. J Cell Mol Med 15: 691-700, 2011.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 691-700
-
-
Zhao, X.L.1
Sun, T.2
Che, N.3
Sun, D.4
Zhao, N.5
Dong, X.Y.6
Gu, Q.7
Yao, Z.8
Sun, B.C.9
-
241
-
-
0032926177
-
Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion
-
Yu Q and Stamenkovic I: Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev 13: 35-48, 1999. (Pubitemid 29045114)
-
(1999)
Genes and Development
, vol.13
, Issue.1
, pp. 35-48
-
-
Yu, Q.1
Stamenkovic, I.2
-
242
-
-
0035863471
-
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity
-
Mitsiades N, Yu WH, Poulaki V, Tsokos M and Stamenkovic I: Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer Res 61: 577-581, 2001. (Pubitemid 32128617)
-
(2001)
Cancer Research
, vol.61
, Issue.2
, pp. 577-581
-
-
Mitsiades, N.1
Yu, W.-H.2
Poulaki, V.3
Tsokos, M.4
Stamenkovic, I.5
-
243
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
Lin WW and Karin M: A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117: 1175-1183, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
244
-
-
36849094431
-
Matrix metalloproteinases as modulators of inflammation
-
DOI 10.1016/j.semcdb.2007.07.003, PII S1084952107000936, Matrix Metalloproteinases
-
Manicone AM and McGuire JK: Matrix metalloproteinases as modulators of inflammation. Semin Cell Dev Biol 19: 34-41, 2008. (Pubitemid 350235986)
-
(2008)
Seminars in Cell and Developmental Biology
, vol.19
, Issue.1
, pp. 34-41
-
-
Manicone, A.M.1
McGuire, J.K.2
-
245
-
-
77952429537
-
Expression of CD133 confers malignant potential by regulating metalloproteinases in human hepatocellular carcinoma
-
Kohga K, Tatsumi T, Takehara T, Tsunematsu H, Shimizu S, Yamamoto M, Sasakawa A, Miyagi T and Hayashi N: Expression of CD133 confers malignant potential by regulating metalloproteinases in human hepatocellular carcinoma. J Hepatol 52: 872-879, 2010.
-
(2010)
J Hepatol
, vol.52
, pp. 872-879
-
-
Kohga, K.1
Tatsumi, T.2
Takehara, T.3
Tsunematsu, H.4
Shimizu, S.5
Yamamoto, M.6
Sasakawa, A.7
Miyagi, T.8
Hayashi, N.9
-
246
-
-
77950266184
-
Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression
-
Littlepage LE, Sternlicht MD, Rougier N, et al: Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression. Cancer Res 70: 2224-2234, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 2224-2234
-
-
Littlepage, L.E.1
Sternlicht, M.D.2
Rougier, N.3
-
247
-
-
33750890673
-
Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway
-
DOI 10.1038/sj.onc.1209706, PII 1209706
-
Cheng JC, Chou CH, Kuo ML and Hsieh CY: Radiationenhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway. Oncogene 25: 7009-7018, 2006. (Pubitemid 44722069)
-
(2006)
Oncogene
, vol.25
, Issue.53
, pp. 7009-7018
-
-
Cheng, J.C.-H.1
Chou, C.H.2
Kuo, M.L.3
Hsieh, C.-Y.4
-
248
-
-
59149105815
-
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9
-
Chen JS, Wang Q, Fu XH, Huang XH, Chen XL, Cao LQ, Chen LZ, Tan HX, Li W, Bi J and Zhang LJ: Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: association with MMP-9. Hepatol Res 39: 177-186, 2009.
-
(2009)
Hepatol Res
, vol.39
, pp. 177-186
-
-
Chen, J.S.1
Wang, Q.2
Fu, X.H.3
Huang, X.H.4
Chen, X.L.5
Cao, L.Q.6
Chen, L.Z.7
Tan, H.X.8
Li, W.9
Bi, J.10
Zhang, L.J.11
-
249
-
-
34547885530
-
An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma
-
DOI 10.1038/sj.onc.1210463, PII 1210463
-
Takafuji V, Forgues M, Unsworth E, Goldsmith P and Wang XW: An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma. Oncogene 26: 6361-6371, 2007. (Pubitemid 47494216)
-
(2007)
Oncogene
, vol.26
, Issue.44
, pp. 6361-6371
-
-
Takafuji, V.1
Forgues, M.2
Unsworth, E.3
Goldsmith, P.4
Wang, X.W.5
-
250
-
-
0029741786
-
Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential
-
DOI 10.1053/jhep.1996.v24.pm0008690399
-
Arii S, Mise M, Harada T, Furutani M, Ishigami S, Niwano M, Mizumoto M, Fukumoto M and Imamura M: Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential. Hepatology 24: 316-322, 1996. (Pubitemid 26260026)
-
(1996)
Hepatology
, vol.24
, Issue.2
, pp. 316-322
-
-
Arii, S.1
Mise, M.2
Harada, T.3
Furutani, M.4
Ishigami, S.-I.5
Niwano, M.6
Mizumoto, M.7
Fukumoto, M.8
Imamura, M.9
-
251
-
-
23044499535
-
The matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients
-
DOI 10.1158/1078-0432.CCR-04-2391
-
Fernández CA, Yan L, Louis G, Yang J, Kutok JL and Moses MA: The matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients. Clin Cancer Res 11: 5390-5395, 2005. (Pubitemid 41060812)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.15
, pp. 5390-5395
-
-
Fernandez, C.A.1
Yan, L.2
Louis, G.3
Yang, J.4
Kutok, J.L.5
Moses, M.A.6
-
252
-
-
34547747873
-
Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer
-
DOI 10.1016/j.ejca.2007.05.013, PII S0959804907004017
-
Kubben FJ, Sier CF, Hawinkels LJ, et al: Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer. Eur J Cancer 43: 1869-1876, 2007. (Pubitemid 47238246)
-
(2007)
European Journal of Cancer
, vol.43
, Issue.12
, pp. 1869-1876
-
-
Kubben, F.J.G.M.1
Sier, C.F.M.2
Hawinkels, L.J.A.C.3
Tschesche, H.4
Van Duijn, W.5
Zuidwijk, K.6
Van Der Reijden, J.J.7
Hanemaaijer, R.8
Griffioen, G.9
Lamers, C.B.H.W.10
Verspaget, H.W.11
-
253
-
-
42249085231
-
Urinary biomarkers predict brain tumor presence and response to therapy
-
DOI 10.1158/1078-0432.CCR-07-1253
-
Smith ER, Zurakowski D, Saad A, Scott RM and Moses MA: Urinary biomarkers predict brain tumor presence and response to therapy. Clin Cancer Res 14: 2378-2386, 2008. (Pubitemid 351551071)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.8
, pp. 2378-2386
-
-
Smith, E.R.1
Zurakowski, D.2
Saad, A.3
Scott, R.M.4
Moses, M.A.5
-
254
-
-
34249914771
-
Upregulation of neutrophil gelatinase-associated lipocalin in oesophageal squamous cell carcinoma: Significant correlation with cell differentiation and tumour invasion
-
DOI 10.1136/jcp.2006.039297
-
Zhang H, Xu L, Xiao D, et al: Upregulation of neutrophil gelatinase-associated lipocalin in oesophageal squamous cell carcinoma: significant correlation with cell differentiation and tumour invasion. J Clin Pathol 60: 555-561, 2007. (Pubitemid 46867169)
-
(2007)
Journal of Clinical Pathology
, vol.60
, Issue.5
, pp. 555-561
-
-
Zhang, H.1
Xu, L.2
Xiao, D.3
Xie, J.4
Zeng, H.5
Wang, Z.6
Zhang, X.7
Niu, Y.8
Shen, Z.9
Shen, J.10
Wu, X.11
Li, E.12
-
255
-
-
4143072599
-
Association of a high activity of matrix metalloproteinase-9 to low levels of tissue inhibitors of metalloproteinase-1 and -3 in human hepatitis B-viral hepatoma cells
-
DOI 10.1016/j.biocel.2004.04.022, PII S1357272504001943
-
Kim JR and Kim CH: Association of a high activity of matrix metalloproteinase-9 to low levels of tissue inhibitors of metalloproteinase-1 and -3 in human hepatitis B-viral hepatoma cells. Int J Biochem Cell Biol 36: 2293-2306, 2004. (Pubitemid 39094450)
-
(2004)
International Journal of Biochemistry and Cell Biology
, vol.36
, Issue.11
, pp. 2293-2306
-
-
Kim, J.-R.1
Kim, C.-H.2
-
256
-
-
33748058811
-
Overexpression of TIMP-1 mediated by recombinant adenovirus in hepatocellular carcinoma cells inhibits proliferation and invasion in vitro
-
Xia D, Yan LN, Xie JG, Tong Y, Yan ML, Wang XP, Zhang MM and Zhao LY: Overexpression of TIMP-1 mediated by recombinant adenovirus in hepatocellular carcinoma cells inhibits proliferation and invasion in vitro. Hepatobiliary Pancreat Dis Int 5: 409-415, 2006. (Pubitemid 44295197)
-
(2006)
Hepatobiliary and Pancreatic Diseases International
, vol.5
, Issue.3
, pp. 409-415
-
-
Xia, D.1
Yan, L.-N.2
Xie, J.-G.3
Tong, Y.4
Yan, M.-L.5
Wang, X.-P.6
Zhang, M.-M.7
Zhao, L.-Y.8
-
257
-
-
0037393850
-
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
-
DOI 10.1038/nm846
-
Qi JH, Ebrahem Q, Moore N, Murphy G, Claesson-Welsh L, Bond M, Baker A and Anand-Apte B: A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med 9: 407-415, 2003. (Pubitemid 36460074)
-
(2003)
Nature Medicine
, vol.9
, Issue.4
, pp. 407-415
-
-
Qi, J.H.1
Ebrahem, Q.2
Moore, N.3
Murphy, G.4
Claesson-Welsh, L.5
Bond, M.6
Baker, A.7
Anand-Apte, B.8
-
258
-
-
34948831072
-
TIMP-3 gene transfection suppresses invasive and metastatic capacity of human hepatocarcinoma cell line HCC-7721
-
Zhang H, Wang YS, Han G and Shi Y: TIMP-3 gene transfection suppresses invasive and metastatic capacity of human hepatocarcinoma cell line HCC-7721. Hepatobiliary Pancreat Dis Int 6: 487-491, 2007. (Pubitemid 47521162)
-
(2007)
Hepatobiliary and Pancreatic Diseases International
, vol.6
, Issue.5
, pp. 487-491
-
-
Zhang, H.1
Wang, Y.-S.2
Han, G.3
Shi, Y.4
-
259
-
-
0035985214
-
Gene expression patterns in human liver cancers
-
DOI 10.1091/mbc.02-02-0023.
-
Chen X, Cheung ST, So S, Fan ST, Barry C, Higgins J, Lai KM, Ji J, Dudoit S, Ng IO, van de Rijn M, Botstein D and Brown PO: Gene expression patterns in human liver cancers. Mol Biol Cell 13: 1929-1939, 2002. (Pubitemid 34651483)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.6
, pp. 1929-1939
-
-
Chen, X.1
Cheung, S.T.2
So, S.3
Fan, S.T.4
Barry, C.5
Higgins, J.6
Lai, K.-M.7
Ji, J.8
Dudoit, S.9
Ng, I.O.L.10
Van De, R.M.11
Botstein, D.12
Brown, P.O.13
-
260
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
Lee JS, Heo J, Libbrecht L, et al: A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 12: 410-416, 2006.
-
(2006)
Nat Med
, vol.12
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
-
261
-
-
34547690632
-
Hypoxia and hepatocellular carcinoma: The therapeutic target for hepatocellular carcinoma
-
Wu XZ, Xie GR and Chen D: Hypoxia and hepatocellular carcinoma: the therapeutic target for hepatocellular carcinoma. J Gastroenterol Hepatol 22: 1178-1182, 2007.
-
(2007)
J Gastroenterol Hepatol
, vol.22
, pp. 1178-1182
-
-
Wu, X.Z.1
Xie, G.R.2
Chen, D.3
-
262
-
-
77952324704
-
Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis
-
Liu L, Zhu XD, Wang WQ, Shen Y, Qin Y, Ren ZG, Sun HC and Tang ZY: Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis. Clin Cancer Res 16: 2740-2750, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2740-2750
-
-
Liu, L.1
Zhu, X.D.2
Wang, W.Q.3
Shen, Y.4
Qin, Y.5
Ren, Z.G.6
Sun, H.C.7
Tang, Z.Y.8
-
263
-
-
54049123723
-
Glycolysis module activated by hypoxia-inducible factor 1alpha is related to the aggressive phenotype of hepatocellular carcinoma
-
Hamaguchi T, Iizuka N, Tsunedomi R, Hamamoto Y, Miyamoto T, Iida M, Tokuhisa Y, Sakamoto K, Takashima M, Tamesa T and Oka M: Glycolysis module activated by hypoxia-inducible factor 1alpha is related to the aggressive phenotype of hepatocellular carcinoma. Int J Oncol 33: 725-731, 2008.
-
(2008)
Int J Oncol
, vol.33
, pp. 725-731
-
-
Hamaguchi, T.1
Iizuka, N.2
Tsunedomi, R.3
Hamamoto, Y.4
Miyamoto, T.5
Iida, M.6
Tokuhisa, Y.7
Sakamoto, K.8
Takashima, M.9
Tamesa, T.10
Oka, M.11
-
264
-
-
20344366296
-
Hepatocellular carcinoma: Molecular pathways and new therapeutic targets
-
DOI 10.1055/s-2005-871200
-
Roberts LR and Gores GJ: Hepatocellular carcinoma: molecular pathways and new therapeutic targets. Semin Liver Dis 25: 212-225, 2005. (Pubitemid 40781073)
-
(2005)
Seminars in Liver Disease
, vol.25
, Issue.2
, pp. 212-225
-
-
Roberts, L.R.1
Gores, G.J.2
-
265
-
-
33746565515
-
Role of Raf Kinase in Cancer: Therapeutic Potential of Targeting the Raf/MEK/ERK Signal Transduction Pathway
-
DOI 10.1053/j.seminoncol.2006.04.002, PII S009377540600176X
-
Gollob JA, Wilhelm S, Carter C and Kelley SL: Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway. Semin Oncol 33: 392-406, 2006. (Pubitemid 44142735)
-
(2006)
Seminars in Oncology
, vol.33
, Issue.4
, pp. 392-406
-
-
Gollob, J.A.1
Wilhelm, S.2
Carter, C.3
Kelley, S.L.4
-
266
-
-
34547469939
-
Raf kinases: Function, regulation and role in human cancer
-
DOI 10.1016/j.bbamcr.2007.05.001, PII S0167488907001164
-
Leicht DT, Balan V, Kaplun A, Singh-Gupta V, Kaplun L, Dobson M and Tzivion G: Raf kinases: function, regulation and role in human cancer. Biochim Biophys Acta 1773: 1196-1212, 2007. (Pubitemid 47161035)
-
(2007)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1773
, Issue.8
, pp. 1196-1212
-
-
Leicht, D.T.1
Balan, V.2
Kaplun, A.3
Singh-Gupta, V.4
Kaplun, L.5
Dobson, M.6
Tzivion, G.7
-
267
-
-
33749836283
-
Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors
-
DOI 10.1038/sj.onc.1209635, PII 1209635
-
Yoshida T, Hisamoto T, Akiba J, et al: Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors. Oncogene 25: 6056-6066, 2006. (Pubitemid 44562404)
-
(2006)
Oncogene
, vol.25
, Issue.45
, pp. 6056-6066
-
-
Yoshida, T.1
Hisamoto, T.2
Akiba, J.3
Koga, H.4
Nakamura, K.5
Tokunaga, Y.6
Hanada, S.7
Kumemura, H.8
Maeyama, M.9
Harada, M.10
Ogata, H.11
Yano, H.12
Kojiro, M.13
Ueno, T.14
Yoshimura, A.15
Sata, M.16
-
268
-
-
33749161559
-
Raf kinase inhibitor protein is downregulated in hepatocellular carcinoma
-
Schuierer MM, Bataille F, Weiss TS, Hellerbrand C and Bosserhoff AK: Raf kinase inhibitor protein is downregulated in hepatocellular carcinoma. Oncol Rep 16: 451-456, 2006.
-
(2006)
Oncol Rep
, vol.16
, pp. 451-456
-
-
Schuierer, M.M.1
Bataille, F.2
Weiss, T.S.3
Hellerbrand, C.4
Bosserhoff, A.K.5
-
269
-
-
36549013178
-
Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection
-
DOI 10.1016/j.jhep.2007.08.018, PII S0168827807005661
-
Schmitz KJ, Wohlschlaeger J, Lang H, Sotiropoulos GC, Malago M, Steveling K, Reis H, Cicinnati VR, Schmid KW and Baba HA: Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection. J Hepatol 48: 83-90, 2008. (Pubitemid 350191996)
-
(2008)
Journal of Hepatology
, vol.48
, Issue.1
, pp. 83-90
-
-
Schmitz, K.J.1
Wohlschlaeger, J.2
Lang, H.3
Sotiropoulos, G.C.4
Malago, M.5
Steveling, K.6
Reis, H.7
Cicinnati, V.R.8
Schmid, K.W.9
Baba, H.A.10
-
270
-
-
0030715557
-
Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma
-
McKillop IH, Schmidt CM, Cahill PA and Sitzmann JV: Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma. Hepatology 26: 1484-1491, 1997. (Pubitemid 27520013)
-
(1997)
Hepatology
, vol.26
, Issue.6
, pp. 1484-1491
-
-
McKillop, I.H.1
Schmidt, C.M.2
Cahill, P.A.3
Sitzmann, J.V.4
-
271
-
-
17344372847
-
Activation of mitogen-activated protein kinases/extracellular signal- regulated kinases in human hepatocellular carcinoma
-
DOI 10.1002/hep.510270409
-
Ito Y, Sasaki Y, Horimoto M, et al: Activation of mitogenactivated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma. Hepatology 27: 951-958, 1998. (Pubitemid 28160479)
-
(1998)
Hepatology
, vol.27
, Issue.4
, pp. 951-958
-
-
Ito, Y.1
Sasaki, Y.2
Horimoto, M.3
Wada, S.4
Tanaka, Y.5
Kasahara, A.6
Ueki, T.7
Hirano, T.8
Yamamoto, H.9
Fujimoto, J.10
Okamoto, E.11
Hayashi, N.12
Hori, M.13
-
272
-
-
34748917797
-
AZD6244 and doxorubicin induce growth suppression and apoptosis in mouse models of hepatocellular carcinoma
-
DOI 10.1158/1535-7163.MCT-07-0162
-
Huynh H, Chow PK and Soo KC: AZD6244 and doxorubicin induce growth suppression and apoptosis in mouse models of hepatocellular carcinoma. Mol Cancer Ther 6: 2468-2476, 2007. (Pubitemid 47480412)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.9
, pp. 2468-2476
-
-
Huynh, H.1
Chow, P.K.H.2
Soo, K.-C.3
-
273
-
-
2442637885
-
Over-expression of c-raf-1 proto-oncogene in liver cirrhosis and hepatocellular carcinoma
-
DOI 10.1016/j.hepres.2004.02.009, PII S1386634604000415
-
Hwang YH, Choi JY, Kim S, Chung ES, Kim T, Koh SS, Lee B, Bae SH, Kim J and Park YM: Over-expression of c-raf-1 protooncogene in liver cirrhosis and hepatocellular carcinoma. Hepatol Res 29: 113-121, 2004. (Pubitemid 38667508)
-
(2004)
Hepatology Research
, vol.29
, Issue.2
, pp. 113-121
-
-
Hwang, Y.H.1
Choi, J.Y.2
Kim, S.3
Chung, E.S.4
Kim, T.5
Koh, S.S.6
Lee, B.7
Bae, S.H.8
Kim, J.9
Park, Y.M.10
-
274
-
-
0035113393
-
Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance
-
Feng DY, Zheng H, Tan Y and Cheng RX: Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance. World J Gastroenterol 7: 33-36, 2001. (Pubitemid 32170895)
-
(2001)
World Journal of Gastroenterology
, vol.7
, Issue.1
, pp. 33-36
-
-
Feng, D.Y.1
Zheng, H.2
Tan, Y.3
Cheng, R.X.4
-
275
-
-
4143074965
-
An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis
-
DOI 10.1016/j.bcp.2004.05.029, PII S0006295204003545
-
Alexia C, Fallot G, Lasfer M, Schweizer-Groyer G and Groyer A: An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis. Biochem Pharmacol 68: 1003-1015, 2004. (Pubitemid 39094263)
-
(2004)
Biochemical Pharmacology
, vol.68
, Issue.6
, pp. 1003-1015
-
-
Alexia, C.1
Fallot, G.2
Lasfer, M.3
Schweizer-Groyer, G.4
Groyer, A.5
-
276
-
-
0035843148
-
Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation
-
DOI 10.1038/sj.onc.1204064
-
Desbois-Mouthon C, Cadoret A, Blivet-van Eggelpoël MJ, Bertrand F, Cherqui G, Perret C and Capeau J: Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene 20: 252-259, 2001. (Pubitemid 32150270)
-
(2001)
Oncogene
, vol.20
, Issue.2
, pp. 252-259
-
-
Desbois-Mouthon, C.1
Cadoret, A.2
Blivet-Van, E.M.-J.3
Bertrand, F.4
Cherqui, G.5
Perret, C.6
Capeau, J.7
-
277
-
-
0344407448
-
Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma
-
Hu TH, Huang CC, Lin PR, Chang HW, Ger LP, Lin YW, Changchien CS, Lee CM and Tai MH: Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma. Cancer 97: 1929-1940, 2003.
-
(2003)
Cancer
, vol.97
, pp. 1929-1940
-
-
Hu, T.H.1
Huang, C.C.2
Lin, P.R.3
Chang, H.W.4
Ger, L.P.5
Lin, Y.W.6
Changchien, C.S.7
Lee, C.M.8
Tai, M.H.9
-
278
-
-
57349087153
-
Pivotal role of mTOR signaling in hepatocellular carcinoma
-
Villanueva A, Chiang DY, Newell P, et al: Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology 135: 1972-1983, 2008.
-
(2008)
Gastroenterology
, vol.135
, pp. 1972-1983
-
-
Villanueva, A.1
Chiang, D.Y.2
Newell, P.3
-
279
-
-
0345006147
-
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
-
DOI 10.1073/pnas.95.15.8847
-
De La CA, Romagnolo B, Billuart P, et al: Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci USA 95: 8847-8851, 1998. (Pubitemid 28350577)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.15
, pp. 8847-8851
-
-
De La, C.A.1
Romagnolo, B.2
Billuart, P.3
Renard, C.-A.4
Buendia, M.-A.5
Soubrane, O.6
Fabre, M.7
Chelly, J.8
Beldjord, C.9
Kahn, A.10
Perret, C.11
-
281
-
-
70349739285
-
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
-
Hoshida Y, Nijman SM, Kobayashi M, et al: Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res 69: 7385-7392, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 7385-7392
-
-
Hoshida, Y.1
Nijman, S.M.2
Kobayashi, M.3
-
282
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z, et al: Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 10: 25-34, 2009.
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
-
283
-
-
33644518982
-
Fibronectin as target for tumor therapy
-
Kaspar M, Zardi L and Neri D: Fibronectin as target for tumor therapy. Int J Cancer 118: 1331-1339, 2006.
-
(2006)
Int J Cancer
, vol.118
, pp. 1331-1339
-
-
Kaspar, M.1
Zardi, L.2
Neri, D.3
-
284
-
-
54949123005
-
Antisense hypoxia-inducible factor 1alpha gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma
-
Liu F, Wang P, Jiang X, Tan G, Qiao H, Jiang H, Krissansen GW and Sun X: Antisense hypoxia-inducible factor 1alpha gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma. Cancer Sci 99: 2055-2061, 2008.
-
(2008)
Cancer Sci
, vol.99
, pp. 2055-2061
-
-
Liu, F.1
Wang, P.2
Jiang, X.3
Tan, G.4
Qiao, H.5
Jiang, H.6
Krissansen, G.W.7
Sun, X.8
-
285
-
-
42949088151
-
Inhibitory effect of hypoxia inducible factor-1 antisense oligonucleotide on growth of human hepatocellular carcinoma cells
-
WeiXing C, Tiantian H, Qun N, Chaohui Y and Ping X: Inhibitory effect of hypoxia inducible factor-1 antisense oligonucleotide on growth of human hepatocellular carcinoma cells. Med Oncol 25: 88-92, 2008.
-
(2008)
Med Oncol
, vol.25
, pp. 88-92
-
-
WeiXing, C.1
Tiantian, H.2
Qun, N.3
Chaohui, Y.4
Ping, X.5
|