메뉴 건너뛰기




Volumn 12, Issue 4, 2006, Pages 410-416

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INVASION; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; FEMALE; FETUS; FETUS CELL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RAT; STEM CELL;

EID: 33645742425     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1377     Document Type: Article
Times cited : (828)

References (40)
  • 1
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • Parkin, D.M., Bray, F., Ferlay, J. & Pisani, P. Estimating the world cancer burden: Globocan 2000. Int. J. Cancer 94, 153-156 (2001).
    • (2001) Int. J. Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 2
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • El Serag, H.B. & Mason, A.C. Rising incidence of hepatocellular carcinoma in the United States. N. Engl. J. Med. 340, 745-750 (1999).
    • (1999) N. Engl. J. Med. , vol.340 , pp. 745-750
    • El Serag, H.B.1    Mason, A.C.2
  • 4
    • 0032898237 scopus 로고    scopus 로고
    • Natural history of untreated nonsurgical hepatocellular carcinoma: Rationale for the design and evaluation of therapeutic trials
    • Llovet, J.M. et al. Natural history of untreated nonsurgical hepatocellular carcinoma: rationale for the design and evaluation of therapeutic trials. Hepatology 29, 62-67 (1999).
    • (1999) Hepatology , vol.29 , pp. 62-67
    • Llovet, J.M.1
  • 5
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. & Weinberg, R.A. The hallmarks of cancer. Cell 100, 57-70 (2000).
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh, A.A. et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403, 503-511 (2000).
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1
  • 7
    • 0034050902 scopus 로고    scopus 로고
    • Systematic variation in gene expression patterns in human cancer cell lines
    • Ross, D.T. et al. Systematic variation in gene expression patterns in human cancer cell lines. Nat. Genet. 24, 227-235 (2000).
    • (2000) Nat. Genet. , vol.24 , pp. 227-235
    • Ross, D.T.1
  • 9
    • 9644254191 scopus 로고    scopus 로고
    • Application of comparative functional genomics to identify best-fit mouse models to study human cancer
    • Lee, J.S. et al. Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat. Genet. 36, 1306-1311 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 1306-1311
    • Lee, J.S.1
  • 10
    • 20344387386 scopus 로고    scopus 로고
    • Comparative functional genomics for identifying models of human cancer
    • Lee, J.S., Grisham, J.W. & Thorgeirsson, S.S. Comparative functional genomics for identifying models of human cancer. Carcinogenesis 26, 1013-1020 (2005).
    • (2005) Carcinogenesis , vol.26 , pp. 1013-1020
    • Lee, J.S.1    Grisham, J.W.2    Thorgeirsson, S.S.3
  • 11
    • 1542410331 scopus 로고    scopus 로고
    • Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays
    • Petkov, P.M. et al. Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays. Hepatology 39, 617-627 (2004).
    • (2004) Hepatology , vol.39 , pp. 617-627
    • Petkov, P.M.1
  • 12
    • 0347623197 scopus 로고    scopus 로고
    • Hepatic stem cells and liver repopulation
    • Dabeva, M.D. & Shafritz, D.A. Hepatic stem cells and liver repopulation. Semin. Liver Dis. 23, 349-362 (2003).
    • (2003) Semin. Liver Dis. , vol.23 , pp. 349-362
    • Dabeva, M.D.1    Shafritz, D.A.2
  • 13
    • 0347623196 scopus 로고    scopus 로고
    • Overview of recent experimental studies on liver stem cells
    • Thorgeirsson, S.S. & Grisham, J.W. Overview of recent experimental studies on liver stem cells. Semin. Liver Dis. 23, 303-312 (2003).
    • (2003) Semin. Liver Dis. , vol.23 , pp. 303-312
    • Thorgeirsson, S.S.1    Grisham, J.W.2
  • 14
    • 4544273428 scopus 로고    scopus 로고
    • Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
    • Lee, J.S. et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 40, 667-676 (2004).
    • (2004) Hepatology , vol.40 , pp. 667-676
    • Lee, J.S.1
  • 15
    • 0030806173 scopus 로고    scopus 로고
    • Changing views of the role of matrix metalloproteinases in metastasis
    • Chambers, A.F. & Matrisian, L.M. Changing views of the role of matrix metalloproteinases in metastasis. J. Natl. Cancer Inst. 89, 1260-1270 (1997).
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1260-1270
    • Chambers, A.F.1    Matrisian, L.M.2
  • 16
    • 0033981473 scopus 로고    scopus 로고
    • The plasminogen activation system in tumor growth, invasion, and metastasis
    • Andreasen, P.A., Egelund, R. & Petersen, H.H. The plasminogen activation system in tumor growth, invasion, and metastasis. Cell. Mol. Life Sci. 57, 25-40 (2000).
    • (2000) Cell. Mol. Life Sci. , vol.57 , pp. 25-40
    • Andreasen, P.A.1    Egelund, R.2    Petersen, H.H.3
  • 17
    • 0035500490 scopus 로고    scopus 로고
    • The many faces of metalloproteases: Cell growth, invasion, angiogenesis and metastasis
    • Chang, C. & Werb, Z. The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol. 11, S37-S43 (2001).
    • (2001) Trends Cell Biol. , vol.11
    • Chang, C.1    Werb, Z.2
  • 18
    • 0037277035 scopus 로고    scopus 로고
    • CD44 and its partners in metastasis
    • Jothy, S. CD44 and its partners in metastasis. Clin. Exp. Metastasis 20, 195-201 (2003).
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 195-201
    • Jothy, S.1
  • 19
    • 1442304609 scopus 로고    scopus 로고
    • Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
    • Yu, Y. et al. Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat. Med. 10, 175-181 (2004).
    • (2004) Nat. Med. , vol.10 , pp. 175-181
    • Yu, Y.1
  • 20
    • 11144357298 scopus 로고    scopus 로고
    • The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
    • Khanna, C. et al. The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis. Nat. Med. 10, 182-186 (2004).
    • (2004) Nat. Med. , vol.10 , pp. 182-186
    • Khanna, C.1
  • 21
    • 1442334887 scopus 로고    scopus 로고
    • Ezrin.a metastatic detERMinant?
    • Curto, M. & McClatchey, A.I. Ezrin.a metastatic detERMinant? Cancer Cell 5, 113-114 (2004).
    • (2004) Cancer Cell , vol.5 , pp. 113-114
    • Curto, M.1    McClatchey, A.I.2
  • 23
    • 27944507386 scopus 로고    scopus 로고
    • Risk factors for early death after liver resection in patients with solitary hepatocellular carcinoma
    • Kondo, K. et al. Risk factors for early death after liver resection in patients with solitary hepatocellular carcinoma. J. Hepatobiliary Pancreat. Surg. 12, 399-404 (2005).
    • (2005) J. Hepatobiliary Pancreat. Surg. , vol.12 , pp. 399-404
    • Kondo, K.1
  • 24
    • 0032819717 scopus 로고    scopus 로고
    • Resection of hepatocellular carcinoma in cirrhotic patients: Longterm results of a prospective study
    • Gouillat, C., Manganas, D., Saguier, G., Duque-Campos, R. & Berard, P. Resection of hepatocellular carcinoma in cirrhotic patients: longterm results of a prospective study. J. Am. Coll. Surg. 189, 282-290 (1999).
    • (1999) J. Am. Coll. Surg. , vol.189 , pp. 282-290
    • Gouillat, C.1    Manganas, D.2    Saguier, G.3    Duque-Campos, R.4    Berard, P.5
  • 25
    • 7044274454 scopus 로고    scopus 로고
    • Genome-scale profiling of gene expression in hepatocellular carcinoma: Classification, survival prediction, and identification of therapeutic targets
    • Lee, J.S. & Thorgeirsson, S.S. Genome-scale profiling of gene expression in hepatocellular carcinoma: classification, survival prediction, and identification of therapeutic targets. Gastroenterology 127, S51-S55 (2004).
    • (2004) Gastroenterology , vol.127
    • Lee, J.S.1    Thorgeirsson, S.S.2
  • 26
    • 0344010691 scopus 로고    scopus 로고
    • Cancer robustness: Tumour tactics
    • Kitano, H. Cancer robustness: tumour tactics. Nature 426, 125 (2003).
    • (2003) Nature , vol.426 , pp. 125
    • Kitano, H.1
  • 27
    • 0034059141 scopus 로고    scopus 로고
    • DNA excision in liver by an albumin-Cre transgene occurs progressively with age
    • Postic, C. & Magnuson, M.A. DNA excision in liver by an albumin-Cre transgene occurs progressively with age. Genesis 26, 149-150 (2000).
    • (2000) Genesis , vol.26 , pp. 149-150
    • Postic, C.1    Magnuson, M.A.2
  • 28
    • 0023339694 scopus 로고
    • An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice
    • Pinkert, C.A., Ornitz, D.M., Brinster, R.L. & Palmiter, R.D. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev. 1, 268-276 (1987).
    • (1987) Genes Dev. , vol.1 , pp. 268-276
    • Pinkert, C.A.1    Ornitz, D.M.2    Brinster, R.L.3    Palmiter, R.D.4
  • 29
    • 1842428601 scopus 로고    scopus 로고
    • Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
    • Huh, C.G. et al. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc. Natl. Acad. Sci. USA 101, 4477-4482 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4477-4482
    • Huh, C.G.1
  • 30
    • 17144474314 scopus 로고    scopus 로고
    • Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
    • Ferrando, A.A. et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 1, 75-87 (2002).
    • (2002) Cancer Cell , vol.1 , pp. 75-87
    • Ferrando, A.A.1
  • 31
    • 0027999434 scopus 로고
    • Cell behavior in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations
    • Sarraf, C. et al. Cell behavior in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations. Am. J. Pathol. 145, 1114-1126 (1994).
    • (1994) Am. J. Pathol. , vol.145 , pp. 1114-1126
    • Sarraf, C.1
  • 32
    • 0037462454 scopus 로고    scopus 로고
    • Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
    • Eferl, R. et al. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell 112, 181-192 (2003).
    • (2003) Cell , vol.112 , pp. 181-192
    • Eferl, R.1
  • 33
    • 0027242180 scopus 로고
    • c-jun is essential for normal mouse development and hepatogenesis
    • Hilberg, F., Aguzzi, A., Howells, N. & Wagner, E.F. c-jun is essential for normal mouse development and hepatogenesis. Nature 365, 179-181 (1993).
    • (1993) Nature , vol.365 , pp. 179-181
    • Hilberg, F.1    Aguzzi, A.2    Howells, N.3    Wagner, E.F.4
  • 34
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan, C.Y. & Nusse, R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20, 781-810 (2004).
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 35
    • 20344374424 scopus 로고    scopus 로고
    • Genetic profiling of human hepatocellular carcinoma
    • Lee, J.S. & Thorgeirsson, S.S. Genetic profiling of human hepatocellular carcinoma. Semin. Liver Dis. 25, 125-132 (2005).
    • (2005) Semin. Liver Dis. , vol.25 , pp. 125-132
    • Lee, J.S.1    Thorgeirsson, S.S.2
  • 36
    • 0031757473 scopus 로고    scopus 로고
    • Primary liver tumour of intermediate (hepatocyte-bile duct cell) phenotype: A progenitor cell tumour?
    • Robrechts, C. et al. Primary liver tumour of intermediate (hepatocyte-bile duct cell) phenotype: a progenitor cell tumour? Liver 18, 288-293 (1998).
    • (1998) Liver , vol.18 , pp. 288-293
    • Robrechts, C.1
  • 37
    • 0033933955 scopus 로고    scopus 로고
    • The immunohistochemical phenotype of dysplastic foci in human liver: Correlation with putative progenitor cells
    • Libbrecht, L., Desmet, V., Van Damme, B. & Roskams, T. The immunohistochemical phenotype of dysplastic foci in human liver: correlation with putative progenitor cells. J. Hepatol. 33, 76-84 (2000).
    • (2000) J. Hepatol. , vol.33 , pp. 76-84
    • Libbrecht, L.1    Desmet, V.2    Van Damme, B.3    Roskams, T.4
  • 38
    • 0029794269 scopus 로고    scopus 로고
    • Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers. Clinical and biological implications
    • Wu, P.C. et al. Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers. Clinical and biological implications. Am. J. Pathol. 149, 1167-1175 (1996).
    • (1996) Am. J. Pathol. , vol.149 , pp. 1167-1175
    • Wu, P.C.1
  • 39
    • 0242609884 scopus 로고    scopus 로고
    • Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence
    • Uenishi, T. et al. Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence. Cancer Sci. 94, 851-857 (2003).
    • (2003) Cancer Sci. , vol.94 , pp. 851-857
    • Uenishi, T.1
  • 40
    • 33645729532 scopus 로고    scopus 로고
    • The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma
    • in the press
    • Durnez, A. et al. The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. Hepatology (in the press).
    • Hepatology
    • Durnez, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.