Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment

Cancer Cell

Volumn 10, Issue 2, 2006, Pages 99-111

  Budhu, Anuradha ^a   Forgues, Marshonna ^a   Ye, Qing Hai ^b   Jia, Hu Liang ^a,b   He, Ping ^c   Zanetti, Krista A ^d   Kammula, Udai S ^a   Chen, Yidong ^e   Qin, Lun Xiu ^b   Tang, Zhao You ^b   Wang, Xin Wei ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b FUDAN UNIVERSITY   (China)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^d Laboratory of Human Carcinogenesis   (United States)

^e NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; CYTOKINE;

ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE FUNCTION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIVER CELL CARCINOMA; LIVER VEIN; MAJOR CLINICAL STUDY; MALE; METASTASIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TH1 CELL; TH2 CELL;

EID: 33747029250     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2006.06.016     Document Type: Article

References (40)

1. Ambs S., Merriam W.G., Ogunfusika M.O., Bennett W.P., Ishibe N., Hussain S.P., Tzeng E.E., Geller D.A., Billiar T.R., and Harris C.C. p53 and vascular endothelial growth factor regulate tumour growth of NOS2-expressing human carcinoma cells. Nat. Med. 4 (1998) 1371-1376
2. Berghella A.M., Contasta I., Pellegrini P., Del Beato T., and Adorno D. Peripheral blood immunological parameters for use as markers of pre-invasive to invasive colorectal cancer. Cancer Biother. Radiopharm. 17 (2002) 43-50
3. Bernards R., and Weinberg R.A. A progression puzzle. Nature 418 (2002) 823
4. Coussens L.M., and Werb Z. Inflammation and cancer. Nature 420 (2002) 860-867
5. D'Arrigo A., Belluco C., Ambrosi A., Digito M., Esposito G., Bertola A., Fabris M., Nofrate V., Mammano E., Leon A., et al. Metastatic transcriptional pattern revealed by gene expression profiling in primary colorectal carcinoma. Int. J. Cancer 115 (2005) 256-262
6. Dave S.S., Wright G., Tan B., Rosenwald A., Gascoyne R.D., Chan W.C., Fisher R.I., Braziel R.M., Rimsza L.M., Grogan T.M., et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N. Engl. J. Med. 351 (2004) 2159-2169
7. de Visser K.E., and Coussens L.M. The interplay between innate and adaptive immunity regulates cancer development. Cancer Immunol. Immunother. 54 (2005) 1143-1152
8. Fidler I.J. Modulation of the organ microenvironment for treatment of cancer metastasis. J. Natl. Cancer Inst. 87 (1995) 1588-1592
9. Fidler I.J., and Kripke M.L. Genomic analysis of primary tumors does not address the prevalence of metastatic cells in the population. Nat. Genet. 34 (2003) 23
10. Golden-Mason L., and Rosen H.R. Natural killer cells: Primary target for hepatitis C virus immune evasion strategies?. Liver Transpl. 12 (2006) 363-372
11. Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
12. Hattori E., Okumoto K., Adachi T., Takeda T., Ito J., Sugahara K., Watanabe H., Saito K., Saito T., Togashi H., and Kawata S. Possible contribution of circulating interleukin-10 (IL-10) to anti-tumor immunity and prognosis in patients with unresectable hepatocellular carcinoma. Hepatol. Res. 27 (2003) 309-314
13. Hofseth L.J., Saito S., Hussain S.P., Espey M.G., Miranda K.M., Araki Y., Jhappan C., Higashimoto Y., He P., Linke S.P., et al. Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc. Natl. Acad. Sci. USA 100 (2003) 143-148
14. Hunter K.W. Host genetics and tumour metastasis. Br. J. Cancer 90 (2004) 752-755
15. Hunter K.W., and Crawford N.P. Germ line polymorphism in metastatic progression. Cancer Res. 66 (2006) 1251-1254
16. Hussain S.P., Hofseth L.J., and Harris C.C. Radical causes of cancer. Nat. Rev. Cancer 3 (2003) 276-285
17. Iizuka N., Oka M., Yamada-Okabe H., Nishida M., Maeda Y., Mori N., Takao T., Tamesa T., Tangoku A., Tabuchi H., et al. Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection. Lancet 361 (2003) 923-929
18. Johansson S., Hall H., Berg L., and Hoglund P. NK cells in autoimmune disease. Curr. Top. Microbiol. Immunol. 298 (2006) 259-277
19. Johnson T.R., Hong S., Van Kaer L., Koezuka Y., and Graham B.S. NK T cells contribute to expansion of CD8(+) T cells and amplification of antiviral immune responses to respiratory syncytial virus. J. Virol. 76 (2002) 4294-4303
20. Kim J.W., Ye Q., Forgues M., Chen Y., Budhu A., Sime J., Hofseth L.J., Kaul R., and Wang X.W. Cancer-associated molecular signature in the tissue samples of patients with cirrhosis. Hepatology 39 (2004) 518-527
21. Lee J.S., Chu I.S., Heo J., Calvisi D.F., Sun Z., Roskams T., Durnez A., Demetris A.J., and Thorgeirsson S.S. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 40 (2004) 667-676
22. Liotta L.A. Mechanisms of cancer invasion and metastasis. Important Adv. Oncol. (1985) 28-41
23. Mann J.R., Backlund M.G., and DuBois R.N. Mechanisms of disease: Inflammatory mediators and cancer prevention. Nat. Clin. Pract. Oncol. 2 (2005) 202-210
24. Mantovani A., Sozzani S., Locati M., Allavena P., and Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23 (2002) 549-555
25. Mueller M.M., and Fusenig N.E. Friends or foes-bipolar effects of the tumour stroma in cancer. Nat. Rev. Cancer 4 (2004) 839-849
26. Nakakura E.K., and Choti M.A. Management of hepatocellular carcinoma. Oncology (Huntingt.) 14 (2000) 1085-1098
27. Paludan S.R., Malmgaard L., Ellermann-Eriksen S., Bosca L., and Mogensen S.C. Interferon (IFN)-gamma and Herpes simplex virus/tumor necrosis factor-alpha synergistically induce nitric oxide synthase 2 in macrophages through cooperative action of nuclear factor-kappa B and IFN regulatory factor-1. Eur. Cytokine Netw. 12 (2001) 297-308
28. Pixley F.J., and Stanley E.R. CSF-1 regulation of the wandering macrophage: complexity in action. Trends Cell Biol. 14 (2004) 628-638
29. Pollard J.W. Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 4 (2004) 71-78
30. Ramaswamy S., Ross K.N., Lander E.S., and Golub T.R. A molecular signature of metastasis in primary solid tumors. Nat. Genet. 33 (2003) 49-54
31. Smyth M.J., Cretney E., Kershaw M.H., and Hayakawa Y. Cytokines in cancer immunity and immunotherapy. Immunol. Rev. 202 (2004) 275-293
32. Spirli C., Fabris L., Duner E., Fiorotto R., Ballardini G., Roskams T., LaRusso N.F., Sonzogni A., Okolicsanyi L., and Strazzabosco M. Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. Gastroenterology 124 (2003) 737-753
33. Tang Z.Y. Hepatocellular carcinoma-Cause, treatment and metastasis. World J. Gastroenterol. 7 (2001) 445-454
34. Thorgeirsson S.S., and Grisham J.W. Molecular pathogenesis of human hepatocellular carcinoma. Nat. Genet. 31 (2002) 339-346
35. Tibshirani R., Hastie T., Narasimhan B., and Chu G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc. Natl. Acad. Sci. USA 99 (2002) 6567-6572
36. van de Vijver M.J., He Y.D., van't Veer L.J., Dai H., Hart A.A., Voskuil D.W., Schreiber G.J., Peterse J.L., Roberts C., Marton M.J., et al. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347 (2002) 1999-2009
37. Van Dommelen S.L., and Degli-Esposti M.A. NKT cells and viral immunity. Immunol. Cell Biol. 82 (2004) 332-341
38. Ye Q.H., Qin L.X., Forgues M., He P., Kim J.W., Peng A.C., Simon R., Li Y., Robles A.I., Chen Y., et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat. Med. 9 (2003) 416-423
39. Yuki K., Hirohashi S., Sakamoto M., Kanai T., and Shimosato Y. Growth and spread of hepatocellular carcinoma. A review of 240 consecutive autopsy cases. Cancer 66 (1990) 2174-2179
40. Zingoni A., Sornasse T., Cocks B.G., Tanaka Y., Santoni A., and Lanier L.L. NK cell regulation of T cell-mediated responses. Mol. Immunol. 42 (2005) 451-454