Significance of vascular endothelial growth factor mRNA expression in invasion and metastasis of hepatocellular carcinoma

Journal of Experimental and Clinical Cancer Research

Volumn 17, Issue 1, 1998, Pages 13-17

  Li, X M ^a   Tang, Z Y ^a   Zhou, G ^a   Lui, Y K ^a   Ye, S L ^a  

^a ZHONGSHAN HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; Invasion; Metastasis; Reverse transcription polymerase chain reaction; Vascular endothelial growth factor

Indexed keywords

VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER INVASION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; DISEASE PROGRESSION; ENDOTHELIAL GROWTH FACTORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; LYMPHOKINES; MALE; MIDDLE AGED; NEOPLASM CIRCULATING CELLS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0031955570     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Folkman J.: Angiogenesis in cancer vascular rheumatoid and other disease. Nature Med. 1: 27-31, 1995.
2. Fidler I. and Ellis L.: The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell. 79:185-187, 1994.
3. Lin G., Hagerstrand I. and Lunderquist A.: Portal blood supply of liver metastasis. AJR. 143: 53-56, 1984.
4. Haratake J. and Scheuer P.J.:An immunohistochemical and ultrastructural study of the sinusoids of hepatocellular carcinoma. Cancer. 65: 1985-1993, 1990.
5. Folkman J.: Clinical applications of research on angiogenesis. N. Eng. J. Med. 333: 1757-1763, 1995.
6. Potenns A.J., Westphol H.R., de Waal R.M., and Ruiter D.J.: The role of vascular permeability factor and basic fibroblast factor in tumor angiogenesis. Biol. Chem. Hoppe-Seyler. 376: 57-70, 1995.
7. Suzuki K., Hayashi N., Miyamoto Y., et al.: Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocelluar carcinoma. Cancer Res. 56:3004-3009, 1996.
8. Chomczysky P., Sacchi N.: Single-step method of RNA isolation by guanidinum thiocyanaye-phenol-chloroform extaction. Anal. Biochem. 162: 156-159, 1987.
9. Houck K.A., Ferrara N.W., Cachianes G., Li B. and Leung D.W.: The vascular endothelial cell growth factor gene family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol. Endocrinol. 5: 1806-1814, 1991.
10. Mise M., Arh S., Higshituji H., Furutani M., Niwano M., Harada T., Ishgami S., Toda Y., Nakayama H., Fukumoto M., Fujita J. and Imamura M.: Clinical significantce of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor. Hepatology. 23: 455-464, 1996.
11. Senger D.R., Galli S.J., Dvorak A.M., Perruzzi C.A., Harvey V.S. and Dvrak H.F.: Tumor cell secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science. 219: 983-985, 1983.
12. Ferrara N., Houck K., Jakeman L. and Leung W. : Molecular and biological properties of the vascular endothelial growth factor family and proteins. Endocr. Rev. 13:18-32, 1992.
13. Kim K.J., Li B., Winer J., Armanini M., Gillett N., Phillips H.S. and Ferrara N.: Inhibition of vascular endothelial growth factor induced angiogenesis suppression tumor growth in vivo. Nature. 362: 841-844, 1993.
14. Rak J.W., Croix B.D.S. and Kerbel R.S.: Consequences of angiogenesis for tumor progression, metastasis and cancer therapy. Anti-cancer Drugs. 6: 3-18, 1995.
15. Shweiki D., Itin A., Soffer D. and Keshet E.: Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-intiated angiogenesis. Nature. 359: 834-845, 1992.
16. Fidler I.J. and Ellis L.M. : The implication of angiogenesis for the biology and therapy of cancer metastasis. Cell. 79:185-188, 1994.
17. Barinaga M.: Designing therapies that target tumor blood vessels. Science. 275: 482-484, 1997.