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Volumn 116, Issue 6, 2001, Pages 838-845

Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma

Author keywords

Flk 1 KDR; Flt 1; Hepatocellular carcinoma; Microvessel density; Vascular endothelial growth factor; VEGF

Indexed keywords

ANTIBODY; CD34 ANTIGEN; ISOPROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 0035190559     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/FXNL-QTN1-94FH-AB3A     Document Type: Article
Times cited : (149)

References (33)
  • 4
    • 0027482251 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract
    • (1993) Cancer Res , vol.53 , pp. 4727-4735
    • Brown, L.F.1    Berse, B.2    Jackman, R.W.3
  • 6
    • 0031038068 scopus 로고    scopus 로고
    • Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, plateletderived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
    • (1997) Cancer Res , vol.57 , pp. 963-969
    • Relf, M.1    LeJeune, S.2    Scott, P.3
  • 8
    • 0029929046 scopus 로고    scopus 로고
    • Strong expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in ovarian borderline and malignant neoplasms
    • (1996) Lab Invest , vol.74 , pp. 1105-1115
    • Abu-Jawdeh, G.M.1    Faix, J.D.2    Niloff, J.3
  • 10
    • 0029790466 scopus 로고    scopus 로고
    • The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade
    • (1996) EMBO J , vol.15 , pp. 4919-4927
    • Davis-Smyth, T.1    Chen, H.2    Park, J.3
  • 11
    • 0027980356 scopus 로고
    • A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1)
    • (1994) Oncogene , vol.9 , pp. 2683-2690
    • Yamane, A.1    Seetharam, L.2    Yamaguchi, S.3
  • 12
    • 19144366561 scopus 로고    scopus 로고
    • Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor
    • (1996) Hepatology , vol.23 , pp. 455-464
    • Mise, M.1    Arii, S.2    Higashituji, H.3
  • 15
    • 0030908887 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: An immunohistochemical study
    • (1997) Hum Pathol , vol.28 , pp. 698-703
    • Chow, N.H.1    Hsu, P.I.2    Lin, X.Z.3
  • 16
    • 0031778206 scopus 로고    scopus 로고
    • Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver
    • (1998) Hepatology , vol.27 , pp. 1554-1562
    • El-Assal, O.N.1    Yamanoi, A.2    Soda, Y.3
  • 18
    • 0031690845 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor is associated with tumor progression in hepatocellular carcinoma
    • (1998) Hum Pathol , vol.29 , pp. 986-991
    • Torimura, T.1    Sata, M.2    Uena, T.3
  • 19
    • 0033071015 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor mRNA expression in patients with chronic hepatitis C and hepatocellular carcinoma
    • (1999) Int J Oncol , vol.14 , pp. 353-359
    • Shimoda, K.1    Mori, M.2    Shibuta, K.3
  • 21
  • 22
    • 0028845813 scopus 로고
    • Prognostic significance of pathologic features of hepatocellular carcinoma: A multivariate analysis of 278 patients
    • (1995) Cancer , vol.76 , pp. 2443-2448
    • Ng, I.O.L.1    Lai, E.C.S.2    Fan, S.T.3
  • 24
    • 0032502843 scopus 로고    scopus 로고
    • Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor
    • (1998) Human Gene Ther , vol.9 , pp. 823-833
    • Kong, H.L.1    Hecht, D.2    Song, W.3
  • 25
    • 0033231069 scopus 로고    scopus 로고
    • Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
    • (1999) Cancer Res , vol.59 , pp. 5412-5416
    • Shaheen, R.M.1    Davis, D.W.2    Liu, W.3
  • 27
    • 0032055524 scopus 로고    scopus 로고
    • The prognostic significance of microvessel density and thymidine phosphorylase expression in squamous cell carcinoma of the esophagus
    • (1998) Cancer , vol.82 , pp. 1225-1232
    • Igarashi, M.1    Dhar, D.K.2    Kubota, H.3
  • 28
    • 0033083125 scopus 로고    scopus 로고
    • Vascularity index as a novel parameter for the in vivo assessment of angiogenesis in patients with cervical carcinoma
    • (1999) Cancer , vol.85 , pp. 651-657
    • Cheng, W.F.1    Lee, C.N.2    Chu, J.S.3
  • 32
    • 0028935608 scopus 로고
    • Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
    • (1995) J Clin Invest , vol.95 , pp. 1789-1797
    • Warren, R.S.1    Yuan, H.2    Matli, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.