메뉴 건너뛰기




Volumn 138, Issue 5, 2010, Pages

Functional Switching of TGF-β1 Signaling in Liver Cancer via Epigenetic Modulation of a Single CpG Site in TTP Promoter

Author keywords

HCC; Methylation; TGF 1; TTP

Indexed keywords

MESSENGER RNA; MYC PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRISTETRAPROLIN;

EID: 77951667118     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.12.044     Document Type: Article
Times cited : (87)

References (30)
  • 1
    • 0034785348 scopus 로고    scopus 로고
    • TGF-β signaling in tumor suppression and cancer progression
    • Derynck R., Akhurst R.J., and Balmain A. TGF-β signaling in tumor suppression and cancer progression. Nat Genet 29 (2001) 117-129
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 2
    • 33750069029 scopus 로고    scopus 로고
    • Escaping from the TGF-β antiproliferative control
    • Seoane J. Escaping from the TGF-β antiproliferative control. Carcinogenesis 27 (2006) 2148-2156
    • (2006) Carcinogenesis , vol.27 , pp. 2148-2156
    • Seoane, J.1
  • 3
    • 0036781812 scopus 로고    scopus 로고
    • c-MYC: more than just a matter of life and death
    • Pelengaris S., Khan M., and Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer 2 (2002) 764-776
    • (2002) Nat Rev Cancer , vol.2 , pp. 764-776
    • Pelengaris, S.1    Khan, M.2    Evan, G.3
  • 4
    • 0035970035 scopus 로고    scopus 로고
    • Defective repression of c-myc in breast cancer cells: a loss at the core of the transforming growth factor β growth arrest program
    • Chen C.R., Kang Y., and Massague J. Defective repression of c-myc in breast cancer cells: a loss at the core of the transforming growth factor β growth arrest program. Proc Natl Acad Sci U S A 98 (2001) 992-999
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 992-999
    • Chen, C.R.1    Kang, Y.2    Massague, J.3
  • 5
    • 0037444273 scopus 로고    scopus 로고
    • Loss of c-myc repression coincides with ovarian cancer resistance to transforming growth factor β growth arrest independent of transforming growth factor β/Smad signaling
    • Baldwin R.L., Tran H., and Karlan B.Y. Loss of c-myc repression coincides with ovarian cancer resistance to transforming growth factor β growth arrest independent of transforming growth factor β/Smad signaling. Cancer Res 63 (2003) 1413-1419
    • (2003) Cancer Res , vol.63 , pp. 1413-1419
    • Baldwin, R.L.1    Tran, H.2    Karlan, B.Y.3
  • 6
    • 1542314236 scopus 로고    scopus 로고
    • Transforming growth factor β-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element
    • Frederick J.P., Liberati N.T., Waddell D.S., et al. Transforming growth factor β-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element. Mol Cell Biol 24 (2004) 2546-2559
    • (2004) Mol Cell Biol , vol.24 , pp. 2546-2559
    • Frederick, J.P.1    Liberati, N.T.2    Waddell, D.S.3
  • 7
    • 0023691647 scopus 로고
    • Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β
    • Coffey Jr. R.J., Bascom C.C., Sipes N.J., et al. Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β. Mol Cell Biol 8 (1988) 3088-3093
    • (1988) Mol Cell Biol , vol.8 , pp. 3088-3093
    • Coffey Jr., R.J.1    Bascom, C.C.2    Sipes, N.J.3
  • 8
    • 33749822544 scopus 로고    scopus 로고
    • Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling
    • Marderosian M., Sharma A., Funk A.P., et al. Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling. Oncogene 25 (2006) 6277-6290
    • (2006) Oncogene , vol.25 , pp. 6277-6290
    • Marderosian, M.1    Sharma, A.2    Funk, A.P.3
  • 9
    • 0032516626 scopus 로고    scopus 로고
    • Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin
    • Carballo E., Lai W.S., and Blackshear P.J. Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin. Science 281 (1998) 1001-1005
    • (1998) Science , vol.281 , pp. 1001-1005
    • Carballo, E.1    Lai, W.S.2    Blackshear, P.J.3
  • 10
    • 0025051298 scopus 로고
    • Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein
    • Lai W.S., Stumpo D.J., and Blackshear P.J. Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein. J Biol Chem 265 (1990) 16556-16563
    • (1990) J Biol Chem , vol.265 , pp. 16556-16563
    • Lai, W.S.1    Stumpo, D.J.2    Blackshear, P.J.3
  • 11
    • 0042530470 scopus 로고    scopus 로고
    • Transcriptional regulation of tristetraprolin by transforming growth factor-β in human T cells
    • Ogawa K., Chen F., Kim Y.J., et al. Transcriptional regulation of tristetraprolin by transforming growth factor-β in human T cells. J Biol Chem 278 (2003) 30373-30381
    • (2003) J Biol Chem , vol.278 , pp. 30373-30381
    • Ogawa, K.1    Chen, F.2    Kim, Y.J.3
  • 12
    • 13244298460 scopus 로고    scopus 로고
    • Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1
    • Lykke-Andersen J., and Wagner E. Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. Genes Dev 19 (2005) 351-361
    • (2005) Genes Dev , vol.19 , pp. 351-361
    • Lykke-Andersen, J.1    Wagner, E.2
  • 13
    • 45249099847 scopus 로고    scopus 로고
    • Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin
    • Stoecklin G., Tenenbaum S.A., Mayo T., et al. Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin. J Biol Chem 283 (2008) 11689-11699
    • (2008) J Biol Chem , vol.283 , pp. 11689-11699
    • Stoecklin, G.1    Tenenbaum, S.A.2    Mayo, T.3
  • 14
    • 0034704847 scopus 로고    scopus 로고
    • Similar but distinct effects of the tristetraprolin/TIS11 immediate-early proteins on cell survival
    • Johnson B.A., Geha M., and Blackwell T.K. Similar but distinct effects of the tristetraprolin/TIS11 immediate-early proteins on cell survival. Oncogene 19 (2000) 1657-1664
    • (2000) Oncogene , vol.19 , pp. 1657-1664
    • Johnson, B.A.1    Geha, M.2    Blackwell, T.K.3
  • 15
    • 0038798677 scopus 로고    scopus 로고
    • A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA
    • Stoecklin G., Gross B., Ming X.F., et al. A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA. Oncogene 22 (2003) 3554-3561
    • (2003) Oncogene , vol.22 , pp. 3554-3561
    • Stoecklin, G.1    Gross, B.2    Ming, X.F.3
  • 16
    • 23044469636 scopus 로고    scopus 로고
    • Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development
    • Park I.Y., Sohn B.H., Choo J.H., et al. Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development. J Cell Biochem 94 (2005) 585-596
    • (2005) J Cell Biochem , vol.94 , pp. 585-596
    • Park, I.Y.1    Sohn, B.H.2    Choo, J.H.3
  • 17
    • 0037073061 scopus 로고    scopus 로고
    • Regulation of transcription elongation by phosphorylation
    • Kobor M.S., and Greenblatt J. Regulation of transcription elongation by phosphorylation. Biochim Biophys Acta 1577 (2002) 261-275
    • (2002) Biochim Biophys Acta , vol.1577 , pp. 261-275
    • Kobor, M.S.1    Greenblatt, J.2
  • 18
    • 33746457753 scopus 로고    scopus 로고
    • Enhanced histone acetylation and transcription: a dynamic perspective
    • Clayton A.L., Hazzalin C.A., and Mahadevan L.C. Enhanced histone acetylation and transcription: a dynamic perspective. Mol Cell 23 (2006) 289-296
    • (2006) Mol Cell , vol.23 , pp. 289-296
    • Clayton, A.L.1    Hazzalin, C.A.2    Mahadevan, L.C.3
  • 19
    • 33749344476 scopus 로고    scopus 로고
    • Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription
    • Ross S., Cheung E., Petrakis T.G., et al. Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription. EMBO J 25 (2006) 4490-4502
    • (2006) EMBO J , vol.25 , pp. 4490-4502
    • Ross, S.1    Cheung, E.2    Petrakis, T.G.3
  • 20
    • 0035542974 scopus 로고    scopus 로고
    • Methyl CpG-binding proteins and transcriptional repression
    • Wade P.A. Methyl CpG-binding proteins and transcriptional repression. Bioessays 23 (2001) 1131-1137
    • (2001) Bioessays , vol.23 , pp. 1131-1137
    • Wade, P.A.1
  • 21
    • 0033521032 scopus 로고    scopus 로고
    • c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads
    • Akiyoshi S., Inoue H., Hanai J., et al. c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads. J Biol Chem 274 (1999) 35269-35277
    • (1999) J Biol Chem , vol.274 , pp. 35269-35277
    • Akiyoshi, S.1    Inoue, H.2    Hanai, J.3
  • 22
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat Rev Genet 3 (2002) 415-428
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 23
    • 0037068351 scopus 로고    scopus 로고
    • Gene silencing in mammalian cells and the spread of DNA methylation
    • Turker M.S. Gene silencing in mammalian cells and the spread of DNA methylation. Oncogene 21 (2002) 5388-5393
    • (2002) Oncogene , vol.21 , pp. 5388-5393
    • Turker, M.S.1
  • 24
    • 33745753087 scopus 로고    scopus 로고
    • Inhibition of IFN-γ transcription by site-specific methylation during T helper cell development
    • Jones B., and Chen J. Inhibition of IFN-γ transcription by site-specific methylation during T helper cell development. EMBO J 25 (2006) 2443-2452
    • (2006) EMBO J , vol.25 , pp. 2443-2452
    • Jones, B.1    Chen, J.2
  • 25
    • 33845645132 scopus 로고    scopus 로고
    • Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers
    • Zou B., Chim C.S., Zeng H., et al. Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology 131 (2006) 1835-1843
    • (2006) Gastroenterology , vol.131 , pp. 1835-1843
    • Zou, B.1    Chim, C.S.2    Zeng, H.3
  • 26
    • 16044369031 scopus 로고    scopus 로고
    • A pathogenetic role for TNF α in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency
    • Taylor G.A., Carballo E., Lee D.M., et al. A pathogenetic role for TNF α in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 4 (1996) 445-454
    • (1996) Immunity , vol.4 , pp. 445-454
    • Taylor, G.A.1    Carballo, E.2    Lee, D.M.3
  • 27
    • 0035930565 scopus 로고    scopus 로고
    • HuA and tristetraprolin are induced following T-cell activation and display distinct but overlapping RNA binding specificities
    • Raghavan A., Robison R.L., McNabb J., et al. HuA and tristetraprolin are induced following T-cell activation and display distinct but overlapping RNA binding specificities. J Biol Chem 276 (2001) 47958-47965
    • (2001) J Biol Chem , vol.276 , pp. 47958-47965
    • Raghavan, A.1    Robison, R.L.2    McNabb, J.3
  • 28
    • 65349120262 scopus 로고    scopus 로고
    • The mRNA binding proteins HuR and Tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis
    • Young L.E., Sanduja S., Bemis-Standoli K., et al. The mRNA binding proteins HuR and Tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology 136 (2009) 1669-1679
    • (2009) Gastroenterology , vol.136 , pp. 1669-1679
    • Young, L.E.1    Sanduja, S.2    Bemis-Standoli, K.3
  • 29
    • 35848935012 scopus 로고    scopus 로고
    • Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation
    • Essafi-Benkhadir K., Onesto C., Stebe E., et al. Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation. Mol Biol Cell 18 (2007) 4648-4658
    • (2007) Mol Biol Cell , vol.18 , pp. 4648-4658
    • Essafi-Benkhadir, K.1    Onesto, C.2    Stebe, E.3
  • 30
    • 64049107465 scopus 로고    scopus 로고
    • miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis
    • Gebeshuber C.A., Zatloukal K., and Martinez J. miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. EMBO Rep 10 (2009) 400-405
    • (2009) EMBO Rep , vol.10 , pp. 400-405
    • Gebeshuber, C.A.1    Zatloukal, K.2    Martinez, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.