-
1
-
-
34250020201
-
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
-
DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007;132:2557-2576 (Pubitemid 46890874)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
2
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: From genes to environment
-
DOI 10.1038/nrc1934, PII NRC1934
-
Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 2006;6:674-687 (Pubitemid 44286000)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.9
, pp. 674-687
-
-
Farazi, P.A.1
Depinho, R.A.2
-
3
-
-
33847069207
-
Genomics and signaling pathways in hepatocellular carcinoma
-
DOI 10.1055/s-2006-960171
-
Villanueva A, Newell P, Chiang DY, Friedman SL, Llovet JM. Genomics and signaling pathways in hepatocellular carcinoma. Semin Liver Dis 2007;27:55-76. (Pubitemid 46269805)
-
(2007)
Seminars in Liver Disease
, vol.27
, Issue.1
, pp. 55-76
-
-
Villanueva, A.1
Newell, P.2
Chiang, D.Y.3
Friedman, S.L.4
Llovet, J.M.5
-
4
-
-
4544273428
-
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
-
DOI 10.1002/hep.20375
-
Lee JS, Chu IS, Heo J, et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 2004;40:667-676 (Pubitemid 39265589)
-
(2004)
Hepatology
, vol.40
, Issue.3
, pp. 667-676
-
-
Lee, J.-S.1
Chu, I.-S.2
Heo, J.3
Calvisi, D.F.4
Sun, Z.5
Roskams, T.6
Durnez, A.7
Demetris, A.J.8
Thorgeirsson, S.S.9
-
5
-
-
0035985214
-
Gene expression patterns in human liver cancers
-
DOI 10.1091/mbc.02-02-0023.
-
Chen X, Cheung ST, So S, et al. Gene expression patterns in human liver cancers. Mol Biol Cell 2002;13:1929-1939 (Pubitemid 34651483)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.6
, pp. 1929-1939
-
-
Chen, X.1
Cheung, S.T.2
So, S.3
Fan, S.T.4
Barry, C.5
Higgins, J.6
Lai, K.-M.7
Ji, J.8
Dudoit, S.9
Ng, I.O.L.10
Van De Rijn, M.11
Botstein, D.12
Brown, P.O.13
-
6
-
-
0037443891
-
Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection
-
DOI 10.1016/S0140-6736(03)12775-4
-
Iizuka N, Oka M, Yamada-Okabe H, et al. Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection. Lancet 2003;361:923-929 (Pubitemid 36332108)
-
(2003)
Lancet
, vol.361
, Issue.9361
, pp. 923-929
-
-
Iizuka, N.1
Oka, M.2
Yamada-Okabe, H.3
Nishida, M.4
Maeda, Y.5
Mori, N.6
Takao, T.7
Tamesa, T.8
Tangoku, A.9
Tabuchi, H.10
Hamada, K.11
Nakayama, H.12
Ishitsuka, H.13
Miyamoto, T.14
Hirabayashi, A.15
Uchimura, S.16
Hamamoto, Y.17
-
7
-
-
4344652974
-
Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpression
-
DOI 10.1158/0008-5472.CAN-04-0292
-
Breuhahn K, Vreden S, Haddad R, et al. Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpression. Cancer Res 2004;64:6058-6064 (Pubitemid 39129404)
-
(2004)
Cancer Research
, vol.64
, Issue.17
, pp. 6058-6064
-
-
Breuhahn, K.1
Vreden, S.2
Haddad, R.3
Beckebaum, S.4
Stippel, D.5
Flemming, P.6
Nussbaum, T.7
Caselmann, W.H.8
Haab, B.B.9
Schirmacher, P.10
-
8
-
-
0037391756
-
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
-
DOI 10.1038/nm843
-
Ye QH, Qin LX, Forgues M, et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med 2003;9:416-423 (Pubitemid 36460075)
-
(2003)
Nature Medicine
, vol.9
, Issue.4
, pp. 416-423
-
-
Ye, Q.-H.1
Qin, L.-X.2
Forgues, M.3
He, P.4
Kim, J.W.5
Peng, A.C.6
Simon, R.7
Li, Y.8
Robles, A.I.9
Chen, Y.10
Ma, Z.-C.11
Wu, Z.-Q.12
Ye, S.-L.13
Liu, Y.-K.14
Tang, Z.-Y.15
Wang, X.W.16
-
9
-
-
5644258323
-
Distinct chromosomal bias of gene expression signatures in the progression of hepatocellular carcinoma
-
DOI 10.1158/0008-5472.CAN-04-1275
-
Midorikawa Y, Tsutsumi S, Nishimura K, et al. Distinct chromosomal bias of gene expression signatures in the progression of hepatocellular carcinoma. Cancer Res 2004;64:7263-7270 (Pubitemid 39372063)
-
(2004)
Cancer Research
, vol.64
, Issue.20
, pp. 7263-7270
-
-
Midorikawa, Y.1
Tsutsumi, S.2
Nishimura, K.3
Kamimura, N.4
Kano, M.5
Sakamoto, H.6
Makuuchi, M.7
Aburatani, H.8
-
10
-
-
33846463379
-
Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
-
DOI 10.1002/hep.21467
-
Boyault S, Rickman DS, de Reynies A, et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 2007;45:42-52. (Pubitemid 46144363)
-
(2007)
Hepatology
, vol.45
, Issue.1
, pp. 42-52
-
-
Boyault, S.1
Rickman, D.S.2
De Reynies, A.3
Balabaud, C.4
Rebouissou, S.5
Jeannot, E.6
Herault, A.7
Saric, J.8
Belghiti, J.9
Franco, D.10
Bioulac-Sage, P.11
Laurent-Puig, P.12
Zucman-Rossi, J.13
-
11
-
-
53049086329
-
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma
-
Chiang DY, Villanueva A, Hoshida Y, et al. Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Res 2008;68:6779-6788
-
(2008)
Cancer Res
, vol.68
, pp. 6779-6788
-
-
Chiang, D.Y.1
Villanueva, A.2
Hoshida, Y.3
-
12
-
-
43149108659
-
Subclass mapping: Identifying common subtypes in independent disease data sets
-
DOI 10.1371/journal.pone.0001195
-
Hoshida Y, Brunet JP, Tamayo P, Golub TR, Mesirov JP. Subclass mapping: identifying common subtypes in independent disease data sets. PLoS ONE 2007;2:e1195. (Pubitemid 351638058)
-
(2007)
PLoS ONE
, vol.2
, Issue.11
-
-
Hoshida, Y.1
Brunet, J.-P.2
Tamayo, P.3
Golub, T.R.4
Mesirov, J.P.5
-
13
-
-
1642529511
-
Metagenes and molecular pattern discovery using matrix factorization
-
DOI 10.1073/pnas.0308531101
-
Brunet JP, Tamayo P, Golub TR, Mesirov JP. Metagenes and molecular pattern discovery using matrix factorization. Proc Natl Acad Sci U S A 2004;101:4164-4169 (Pubitemid 38405900)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.12
, pp. 4164-4169
-
-
Brunet, J.-P.1
Tamayo, P.2
Golub, T.R.3
Mesirov, J.P.4
-
14
-
-
57349090407
-
Gene expression in fixed tissues and outcome in hepatocellular carcinoma
-
Hoshida Y, Villanueva A, Kobayashi M, et al. Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 2008;359:1995-2004.
-
(2008)
N Engl J Med
, vol.359
, pp. 1995-2004
-
-
Hoshida, Y.1
Villanueva, A.2
Kobayashi, M.3
-
15
-
-
51049111671
-
Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases
-
Xu L, Shen SS, Hoshida Y, et al. Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Mol Cancer Res 2008;6:760-769
-
(2008)
Mol Cancer Res
, vol.6
, pp. 760-769
-
-
Xu, L.1
Shen, S.S.2
Hoshida, Y.3
-
16
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
DOI 10.1073/pnas.0506580102
-
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 2005;102:15545-15550 (Pubitemid 41528093)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
17
-
-
0037308463
-
Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy
-
DOI 10.1016/S0168-8278(02)00360-4
-
Imamura H, Matsuyama Y, Tanaka E, et al. Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy. J Hepatol 2003;38:200-207 (Pubitemid 36169630)
-
(2003)
Journal of Hepatology
, vol.38
, Issue.2
, pp. 200-207
-
-
Imamura, H.1
Matsuyama, Y.2
Tanaka, E.3
Ohkubo, T.4
Hasegawa, K.5
Miyagawa, S.6
Sugawara, Y.7
Minagawa, M.8
Takayama, T.9
Kawasaki, S.10
Makuuchi, M.11
-
18
-
-
33845760039
-
Prevention of hepatocellular carcinoma recurrence with alpha-interferon after liver resection in HCV cirrhosis
-
DOI 10.1002/hep.21415
-
Mazzaferro V, Romito R, Schiavo M, et al. Prevention of hepatocellular carcinoma recurrence with α-interferon after liver resection in HCV cirrhosis. Hepatology 2006;44:1543-1554 (Pubitemid 44970357)
-
(2006)
Hepatology
, vol.44
, Issue.6
, pp. 1543-1554
-
-
Mazzaferro, V.1
Romito, R.2
Schiavo, M.3
Mariani, L.4
Camerini, T.5
Bhoori, S.6
Capussotti, L.7
Calise, F.8
Pellicci, R.9
Belli, G.10
Tagger, A.11
Colombo, M.12
Bonino, F.13
Majno, P.14
Llovet, J.M.15
-
19
-
-
2442689079
-
A versatile assay for high-throughput gene expression profiling on universisal array matrices
-
DOI 10.1101/gr.2167504
-
Fan JB, Yeakley JM, Bibikova M, et al. A versatile assay for high-throughput gene expression profiling on universal array matrices. Genome Res 2004;14:878-885 (Pubitemid 38660505)
-
(2004)
Genome Research
, vol.14
, Issue.5
, pp. 878-885
-
-
Fan, J.-B.1
Yeakley, J.M.2
Bibikova, M.3
Chudin, E.4
Wickham, E.5
Chen, J.6
Doucet, D.7
Rigault, P.8
Zhang, B.9
Shen, R.10
McBride, C.11
Li, H.-R.12
Fu, X.-D.13
Oliphant, A.14
Barker, D.L.15
Chee, M.S.16
-
20
-
-
33745220780
-
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
-
DOI 10.1172/JCI27236
-
Kaposi-Novak P, Lee JS, Gomez-Quiroz L, Coulouarn C, Factor VM, Thorgeirsson SS. Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. J Clin Invest 2006;116:1582-1595 (Pubitemid 43911012)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.6
, pp. 1582-1595
-
-
Kaposi-Novak, P.1
Lee, J.-S.2
Gomez-Quiroz, L.3
Coulouarn, C.4
Factor, V.M.5
Thorgeirsson, S.S.6
-
21
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
Lee JS, Heo J, Libbrecht L, et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006;12:410-416
-
(2006)
Nat Med
, vol.12
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
-
22
-
-
28844480321
-
Management of hepatocellular carcinoma
-
Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005;42:1208-1236
-
(2005)
Hepatology
, vol.42
, pp. 1208-1236
-
-
Bruix, J.1
Sherman, M.2
-
24
-
-
9644254191
-
Application of comparative functional genomics to identify best-fit mouse models to study human cancer
-
DOI 10.1038/ng1481
-
Lee JS, Chu IS, Mikaelyan A, et al. Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat Genet 2004;36:1306-1311 (Pubitemid 39577940)
-
(2004)
Nature Genetics
, vol.36
, Issue.12
, pp. 1306-1311
-
-
Lee, J.-S.1
Chu, I.-S.2
Mikaelyan, A.3
Calvisi, D.F.4
Heo, J.5
Reddy, J.K.6
Thorgeirsson, S.S.7
-
25
-
-
40449099255
-
EpCAM and α-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma
-
DOI 10.1158/0008-5472.CAN-07-6013
-
Yamashita T, Forgues M, Wang W, et al. EpCAM and α-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. Cancer Res 2008;68:1451-1461 (Pubitemid 351346853)
-
(2008)
Cancer Research
, vol.68
, Issue.5
, pp. 1451-1461
-
-
Yamashita, T.1
Forgues, M.2
Wang, W.3
Jin, W.K.4
Ye, Q.5
Jia, H.6
Budhu, A.7
Zanetti, K.A.8
Chen, Y.9
Qin, L.-X.10
Tang, Z.-Y.11
Xin, W.W.12
-
26
-
-
11144236505
-
MTOR and P70 S6 kinase expression in primary liver neoplasms
-
DOI 10.1158/1078-0432.CCR-04-0941
-
Sahin F, Kannangai R, Adegbola O, Wang J, Su G, Torbenson M. mTOR and P70 S6 kinase expression in primary liver neoplasms. Clin Cancer Res 2004;10:8421-8425 (Pubitemid 40053405)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.24
, pp. 8421-8425
-
-
Sahin, F.1
Kannangai, R.2
Adegbola, O.3
Wang, J.4
Su, G.5
Torbenson, M.6
-
27
-
-
57349087153
-
Pivotal role of mTOR signaling in hepatocellular carcinoma
-
Villanueva A, Chiang DY, Newell P, et al. Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology 2008;135:1972-1983
-
(2008)
Gastroenterology
, vol.135
, pp. 1972-1983
-
-
Villanueva, A.1
Chiang, D.Y.2
Newell, P.3
-
29
-
-
0029964851
-
Signal transduction through β-catenin and specification of cell fate during embryogenesis
-
Miller JR, Moon RT. Signal transduction through β-catenin and specification of cell fate during embryogenesis. Genes Dev 1996;10:2527-2539
-
(1996)
Genes Dev
, vol.10
, pp. 2527-2539
-
-
Miller, J.R.1
Moon, R.T.2
-
31
-
-
33846846541
-
Differential effects of inactivated Axin1 and activated β-catenin mutations in human hepatocellular carcinomas
-
DOI 10.1038/sj.onc.1209824, PII 1209824
-
Zucman-Rossi J, Benhamouche S, Godard C, et al. Differential effects of inactivated Axin1 and activated β-catenin mutations in human hepatocellular carcinomas. Oncogene 2007;26:774-780 (Pubitemid 46204256)
-
(2007)
Oncogene
, vol.26
, Issue.5
, pp. 774-780
-
-
Zucman-Rossi, J.1
Benhamouche, S.2
Godard, C.3
Boyault, S.4
Grimber, G.5
Balabaud, C.6
Cunha, A.S.7
Bioulac-Sage, P.8
Perret, C.9
-
32
-
-
24644487312
-
TGF-β and epithelial-to-mesenchymal transitions
-
Zavadil J, Bottinger EP. TGF-β and epithelial-to-mesenchymal transitions. Oncogene 2005;24:5764-5774
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Bottinger, E.P.2
-
33
-
-
27744527762
-
Laminin-5 with transforming growth factor-β1 induces epithelial to mesenchymal transition in hepatocellular carcinoma
-
DOI 10.1053/j.gastro.2005.09.055, PII S0016508505019980
-
Giannelli G, Bergamini C, Fransvea E, Sgarra C, Antonaci S. Laminin-5 with transforming growth factor-β1 induces epithelial to mesenchymal transition in hepatocellular carcinoma. Gastroenterology 2005;129:1375-1383 (Pubitemid 41597379)
-
(2005)
Gastroenterology
, vol.129
, Issue.5
, pp. 1375-1383
-
-
Giannelli, G.1
Bergamini, C.2
Fransvea, E.3
Sgarra, C.4
Antonaci, S.5
-
34
-
-
34249028607
-
PDGF essentially links TGF-β signaling to nuclear β-catenin accumulation in hepatocellular carcinoma progression
-
DOI 10.1038/sj.onc.1210121, PII 1210121
-
Fischer AN, Fuchs E, Mikula M, Huber H, Beug H, Mikulits W. PDGF essentially links TGF-β signaling to nuclear β-catenin accumulation in hepatocellular carcinoma progression. Oncogene 2007;26:3395-3405 (Pubitemid 46788880)
-
(2007)
Oncogene
, vol.26
, Issue.23
, pp. 3395-3405
-
-
Fischer, A.N.M.1
Fuchs, E.2
Mikula, M.3
Huber, H.4
Beug, H.5
Mikulits, W.6
-
35
-
-
46249085489
-
Transforming growth factor-β gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer
-
DOI 10.1002/hep.22283
-
Coulouarn C, Factor VM, Thorgeirsson SS. Transforming growth factor-β gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer. Hepatology 2008;47:2059-2067 (Pubitemid 351945572)
-
(2008)
Hepatology
, vol.47
, Issue.6
, pp. 2059-2067
-
-
Coulouarn, C.1
Factor, V.M.2
Thorgeirsson, S.S.3
-
36
-
-
33645007189
-
SMAD3-dependent nuclear translocation of β-catenin is required for TGF-β1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells
-
Jian H, Shen X, Liu I, Semenov M, He X, Wang XF. SMAD3-dependent nuclear translocation of β-catenin is required for TGF-β1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells. Genes Dev 2006;20:666-674
-
(2006)
Genes Dev
, vol.20
, pp. 666-674
-
-
Jian, H.1
Shen, X.2
Liu, I.3
Semenov, M.4
He, X.5
Wang, X.F.6
-
37
-
-
5844370499
-
Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma
-
DOI 10.1056/NEJM199606133342402
-
Muto Y, Moriwaki H, Ninomiya M, et al. Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. Hepatoma Prevention Study Group. N Engl J Med 1996;334:1561-1567 (Pubitemid 26177483)
-
(1996)
New England Journal of Medicine
, vol.334
, Issue.24
, pp. 1561-1567
-
-
Muto, Y.1
Moriwaki, H.2
Ninomiya, M.3
Adachi, S.4
Saito, A.5
Takasaki, T.6
Tanaka, T.7
Tsurumi, K.8
Okuno, M.9
Tomita, E.10
Nakamura, T.11
Kojima, T.12
-
38
-
-
54449083925
-
Molecular targeted therapies in hepatocellular carcinoma
-
Llovet JM, Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology 2008;48:1312-1327
-
(2008)
Hepatology
, vol.48
, pp. 1312-1327
-
-
Llovet, J.M.1
Bruix, J.2
|