The awakening of an advanced malignant cancer: An insult to the mitochondrial genome

Biochimica et Biophysica Acta - General Subjects

Volumn 1820, Issue 5, 2012, Pages 652-662

  Cook, Cody C ^a   Higuchi, Masahiro ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Cancer; Depletion; Mitochondria; Mitochondrial DNA; Mutation

Indexed keywords

BIOLOGICAL MARKER; DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; REACTIVE OXYGEN METABOLITE;

ADVANCED CANCER; BINDING SITE; CANCER GROWTH; CANCER RISK; CARCINOGENESIS; DISEASE MARKER; GENE AMPLIFICATION; GENE DOSAGE; HAPLOTYPE; HETEROPLASMY; HUMAN; INTRACELLULAR SIGNALING; MALIGNANT NEOPLASTIC DISEASE; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL GENOME; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MUTATIONAL ANALYSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW; SEGREGATION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; TRANSCRIPTION REGULATION;

DISEASE PROGRESSION; DNA, MITOCHONDRIAL; GENOME, MITOCHONDRIAL; HUMANS; MUTATION; NEOPLASMS;

EID: 84859432042     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2011.08.017     Document Type: Review

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