High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

Nature Genetics

Volumn 28, Issue 2, 2001, Pages 147-150

  Coller, Hilary A ^a   Khrapko, Konstantin ^b   Bodyak, Natalya D ^b   Nekhaeva, Ekaterina ^b   Herrero Jimenez, Pablo ^c   Thilly, William G ^c  

^a USA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Massachusetts Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

ARTICLE; CANCER GENETICS; CELL DIVISION; DNA REPLICATION; GENE MUTATION; HUMAN; HUMAN TISSUE; POINT MUTATION; PRIORITY JOURNAL; SOMATIC MUTATION;

AGED; AGED, 80 AND OVER; COLONIC NEOPLASMS; COMPUTER SIMULATION; DNA, MITOCHONDRIAL; EPITHELIAL CELLS; HUMANS; MIDDLE AGED; MODELS, BIOLOGICAL; MUTATION; NEOPLASMS; POINT MUTATION; SELECTION (GENETICS);

EID: 0034972303     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/88859     Document Type: Article

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