Mutations in mitochondrial DNA polymerase-γ promote breast tumorigenesis

Journal of Human Genetics

Volumn 54, Issue 9, 2009, Pages 516-524

  Singh, Keshav K ^a   Ayyasamy, Vanniarajan ^a   Owens, Kjerstin M ^a   Koul, Manika Sapru ^b   Vujcic, Marija ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b TRANSGENOMIC INC   (United States)

Author keywords

Breast cancer; Mitochondria; Mitochondrial; MtDNA; Mutation; POLG

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA;

ARTICLE; BREAST CARCINOGENESIS; CONTROLLED STUDY; DNA CONTENT; EXON; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRON; MISSENSE MUTATION; MITOCHONDRIAL DNA DEPLETION; MUTATIONAL ANALYSIS; PROTEIN DOMAIN; SOMATIC MUTATION;

BREAST NEOPLASMS; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; FEMALE; GENOME, MITOCHONDRIAL; HUMANS; MITOCHONDRIA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOPLASM INVASIVENESS; PLASMIDS; TUMOR CELLS, CULTURED;

EID: 70349606857     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1038/jhg.2009.71     Document Type: Article

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