Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways

Journal of Cell Biology

Volumn 156, Issue 2, 2002, Pages 299-313

  Janda, Elzbieta ^a   Lehmann, Kerstin ^b,d   Killisch, Iris ^a   Jechlinger, Martin ^a   Herzig, Michaela ^a   Downward, Julian ^b   Beug, Hartmut ^a   Grünert, Stefan ^a,c  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c MetaGen GmbH ^*  (Austria)

^d MetaGen Pharmaceuticals GmbH   (Germany)

Author keywords

EMT; MAPK; Metastasis; PI3K; TGF

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CANCER INVASION; CARCINOGENESIS; CELL STRUCTURE; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENETIC TRANSFORMATION; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; MOUSE; NONHUMAN; ONCOGENE RAS; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPINDLE CELL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL MOVEMENT; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; HEPATOCYTE GROWTH FACTOR; MAMMARY GLANDS, ANIMAL; MAP KINASE SIGNALING SYSTEM; MESODERM; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR WEIGHT; MUTATION; NEOPLASM METASTASIS; ONCOGENE PROTEIN P21(RAS); SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 0037148532     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200109037     Document Type: Article

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