Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a

Cancer Letters

Volumn 268, Issue 1, 2008, Pages 31-37

  Suzuki, Seigo ^a   Naito, Akihiro ^a   Asano, Takayuki ^b   Evans, Teresa T ^a   Reddy, Shrikanth A G ^b   Higuchi, Masahiro ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

AKT; Mitochondrial DNA; TNF

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 9; CYCLOHEXIMIDE; MITOCHONDRIAL DNA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN SYNTHESIS INHIBITOR; RECOMBINANT TUMOR NECROSIS FACTOR;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; HUMAN; HUMAN CELL; MITOCHONDRIAL DNA DEPLETION; MYELOID LEUKEMIA; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL LINE, TUMOR; CHROMONES; CLONE CELLS; CYCLOHEXIMIDE; DNA, MITOCHONDRIAL; HUMANS; LEUKEMIA, MYELOID; MORPHOLINES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 48149083134     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.03.020     Document Type: Article

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