Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells

Biochemical Journal

Volumn 348, Issue 2, 2000, Pages 425-432

  Lee, Hsin Chen ^a   Yin, Pen Hui ^a   Lu, Ching You ^a   Chi, Chin Wen ^a   Wei, Yau Huei ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Aging; Cell cycle arrest; Copy number; Hydrogen peroxide; MtDNA; Reactive oxygen species

Indexed keywords

BUTHIONINE SULFOXIMINE; GENISTEIN; HYDROGEN PEROXIDE; MEVINOLIN; MIMOSINE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; TETRAZOLIUM;

AGING; ARTICLE; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL MEMBRANE POTENTIAL; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; LUNG FIBROBLAST; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY CHAIN;

CELL CYCLE; CELL DIVISION; CELL LINE; CELL SURVIVAL; DNA, MITOCHONDRIAL; FIBROBLASTS; GENISTEIN; HUMANS; HYDROGEN PEROXIDE; LOVASTATIN; LUNG; MIMOSINE; MITOCHONDRIA; OXIDATIVE STRESS; RHODAMINE 123; TETRAZOLIUM SALTS;

EID: 0034214103     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3480425     Document Type: Article

References (35)

1. 1 Chance, B., Sies, H. and Boveris, A. (1979) Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59, 527-604
2. 2 Papa, S. (1996) Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications. Biochim. Biophys. Acta 1276, 87-105
3. 3 Wei, Y. H. (1998) Oxidative stress and mitochondrial DNA mutations in human aging. Proc. Soc. Exp. Biol. Med. 217, 53-63
4. 4 Lee, H. C., Lu, C. Y., Fahn, H. J. and Wei, Y. H. (1998) Aging-and smoking-associated alteration in the relative content of mitochondrial DNA in human lung. FEBS Lett. 441, 292-296
5. 5 Fahn, H. J., Wang, L. S., Hsieh, R. H., Chang, S. C. Kao, S. H., Huang, M. H. and Wei, Y. H. (1996) Age-related 4,977 bp deletion in human lung mitochondrial DNA. Am. J. Respir. Crit. Care Med. 154, 1141-1145
6. 6 Fahn, H. J., Wang, L. S., Kao, S. H., Chang, S. C., Huang, M. H. and Wei, Y. H. (1998) Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues. Am. J. Respir. Cell Mol. Biol. 19, 901-909
7. 7 Lee, H. C. Lim, M. L. R., Lu, C. Y. Liu, V. W. S., Fahn, H. J., Zhang, C., Nagley, P. and Wei, Y. H. (1999) Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging-smoking enhances oxidative stress on the aged tissues. Arch. Biochem. Biophys. 362, 309-316
8. 8 Wei, Y. H., Kao, S. H. and Lee, H. C. (1996) Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging. Ann. N.Y. Acad. Sci. 786, 24-43
9. 9 Lu, C. Y., Lee, H. C., Fahn, H. J. and Wei, Y. H. (1999) Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin. Mutat. Res. 423, 11-21
10. 10 Gadaleta, M. N., Rainaldi, G., Lezza, A. M. S., Milella, F., Fracasso, F. and Cantatore, P. (1992) Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats. Mutat. Res. 275, 181-193
11. 11 Barrientos, A., Casademont, J., Cardellach, F., Estivill, X., Urbano-Marquez, A. and Nunes, V. (1997) Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging. Mol. Brain Res. 52, 284-289
12. 12 Ames, B. N., Shigenaga, M. K. and Hagen, T. M. (1995) Mitochondrial decay in aging. Biochim. Biophys. Acta 1271, 165-170
13. 13 Sohal, R. S. and Sohal, B. H. (1991) Hydrogen peroxide release by mitochondria increases during aging. Mech. Ageing Dev. 57, 187-202
14. 14 Richter, C., Gogvadze, V., Laffranchi, R., Schlapbach, R., Schnizer, M., Surer, M., Walter, P. and Yaffee, M. (1995) Oxidants in mitochondria: from physiology to disease. Biochim. Biophys. Acta 1271, 67-74
15. 15 Sohal, R. S., Sohal, B. H. and Orr, W. C. (1995) Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage and longevity in ditterent species of flies. Free Radical Biol. Med. 19, 499-504
16. 16 Sen, C. K. and Packer, L. (1996) Antioxidant and redox regulation of gene transcription. FASEB J. 10, 709-720
17. 17 Lander, H. M. (1997) An essential role for free radicals and derived species in signal transduction. FASEB J. 11, 118-124
18. 18 Burdon, R. H. (1995) Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radical Biol. Med. 18, 775-794
19. 19 Poyton, R. O. and McEwen, J. E. (1996) Crosstalk between nuclear and mitochondrial genomes. Annu. Rev. Biochem. 65, 563-607
20. 20 Scarpulla, R. C. (1997) Nuclear control of respiratory chain expression in mammalian cells. J. Bioenerg. Biomembr. 29, 109-119
21. 21 Lee, H. C. and Wei, Y. H. (2000) Mitochondrial role in life and death of the cell. J. Biomed. Sci. 7, 2-15
22. 22 Maftah, A., Petit, J. M., Ratinaud, M. H. and Julien, R. (1989) 10-N nonyl acridine orange: a fluorescent probe which stains mitochondria independently of their energetic state. Biochem. Biophys. Res. Commun. 164, 185-190
23. 23 Petit, J. M., Maftah, A., Ratinaud, M. H. and Julien, R. (1992) 10-N nonyl aridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria. Eur. J. Biochem. 209, 267-273
24. 24 Mancini, M., Anderson, B. O., Caldwell, E., Sedghinasab, M., Paty, P. B. and Hockenbery, D. M. (1997) Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line. J. Cell Biol. 138, 449-469
25. 25 Rothe, G. and Valet, G. (1990) Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlofofluorescin. J. Leuk. Biol. 47, 440-448
26. 26 Garcia-Ruiz, C., Colell, A., Morales, A., Kaplowitz, N. and Fernandez-Checa, J. C. (1995) Role of oxidative stress generated from mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-κB: studies with isolated mitochondria and rat hepatocytes. Mol. Pharmacol. 48, 825-834
27. 27 Pagliacci, M. C., Spinozzi, F., Migliorati, G., Fumi, G., Smacchia, M., Grignani, F., Riccardi, C. and Nicoletti, I. (1993) Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival. Eur. J. Cancer 29A, 1573-1577
28. 28 Robin, E. D. and Wong, R. (1988) Mitochondrial DNA molecules and virtual number of mitochondria per cell in mammalian cells. J. Cell. Physiol. 136, 507-513
29. 29 Renis, M., Cantatore, P., Polosa, P. L., Fracasso, F. and Gadaleta, M. N. (1989) Content of mitochondrial DNA and of three mitochondrial RNAs in developing and adult cerebellum. J. Neurochem. 52, 750-754
30. 30 Shay, J. W., Pierce, D. J. and Werbin, H. (1990) Mitochondrial DNA copy number is proportional to total cell DNA under a variety of growth conditions. J. Biol. Chem. 265, 14802-14807
31. 31 Williams, R. S., Salmons, S., Newsholme, E. A., Kaulman, R. E. and Mellor, J. (1986) Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle. J. Biol. Chem. 261, 376-380
32. 2: senescence-like growth arrest or apoptosis. Cell Growth Differ. 8, 589-598
33. 1 arrest but not cell replication. Biochem. J. 332, 43-50
34. 34 Suzuki, H., Kumagai, T., Goto, A. and Sugiura, T. (1998) Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells. Biochem. Biophys. Res. Commun. 249, 542-545
35. 35 Sazer, S. and Sherwood, S. W. (1990) Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast. J. Cell Sci. 97, 509-516