Reversible regulation of metastasis by ROS-generating mtDNA mutations

Mitochondrion

Volumn 8, Issue 4, 2008, Pages 339-344

  Ishikawa, Kaori ^a,b   Koshikawa, Nobuko ^c   Takenaga, Keizo ^d   Nakada, Kazuto ^a   Hayashi, Jun Ichi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c CHIBA CANCER CENTER   (Japan)

^d SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

Metastasis; mtDNA mutation; mtDNA transfer technology; Nuclear gene regulation; ROS overproduction

Indexed keywords

MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

ARTICLE; CANCER CONTROL; GENE FUNCTION; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; MALIGNANT TRANSFORMATION; METASTASIS; MISSENSE MUTATION; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SCAVENGING SYSTEM; TARGET CELL; TUMOR CELL; UPREGULATION;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; DNA, MITOCHONDRIAL; DNA, NEOPLASM; ELECTRON TRANSPORT COMPLEX I; FREE RADICAL SCAVENGERS; HYBRID CELLS; MICE; MUTATION, MISSENSE; NEOPLASM METASTASIS; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 52749089104     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2008.07.006     Document Type: Article

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