Cell-surface-bound nucleic acids: Free and cell-surface-bound nucleic acids in blood of healthy donors and breast cancer patients

Annals of the New York Academy of Sciences

Volumn 1022, Issue , 2004, Pages 221-227

  Laktionov, Pavel P ^a   Tamkovich, Svetlana N ^a   Rykova, Elena Yu ^a   Bryzgunova, Olga E ^a   Starikov, Andrey V ^b   Kuznetsova, Nina P ^b   Vlassov, Valentin V ^a  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

^b National Novosibirsk Regional Oncologic Dispensary   (Russian Federation)

Author keywords

Breast cancer; Cell surface bound DNA; Cell surface bound RNA; Extracellular DNA; Extracellular RNA; Fibroadenoma

Indexed keywords

DNA; DNA FRAGMENT; EDETIC ACID; NUCLEIC ACID; RNA; TRYPSIN;

BLOOD; BREAST CANCER; CANCER PATIENT; CELL SURFACE; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DIFFERENTIAL DIAGNOSIS; ERYTHROCYTE; HUMAN; HUMAN CELL; LEUKOCYTE; PLASMA;

EID: 3242703880     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1318.034     Document Type: Conference Paper

References (19)

1. Sozzi, G. et al. 2001. Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients. Cancer Res. 61: 4675-4678.
2. RAINER, T. et al. 2001. Derivation of a prediction rule for posttraumatic organ failure using plasma DNA and other variables. Ann. N.Y. Acad. Sci. 945: 211-220.
3. VASILYEVA, I. 2001. Low-molecular-weight DNA in blood plasma as an index of the influence of ionizing radiation. Ann. N. Y. Acad. Sci. 945: 221-228.
4. SILVA, J. et al. 1999. Presence of tumor DNA in plasma of breast cancer patients: clinicopathological correlations. Cancer Res. 59: 3251-3256.
5. Lo, Y.M.D. et al. 1998. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am. J. Hum. Genet. 62: 768-775.
6. RAPTIS, L. et al. 1980. Quantitation and characterization of plasma DNA in normals and patients with systemic lupus erythematosus. J. Clin. Invest. 66: 1391-1399.
7. HAMILTON, T. et al. 1975. Ribonucleic acid in plasma from normal adults and multiple myeloma patients. Clin. Chem. 25: 1774-1779.
8. NG, E. et al. 2002. Presence of filterable and nonfilterable mRNA in the plasma of cancer patients and healthy individuals. Clin. Chem. 48: 1212-1217.
9. KOPRESKI, M.S. et al. 1999. Detection of tumor messenger RNA in the serum of patients with malignant melanoma. Clin. Cancer Res. 5: 1961-1965.
10. BENNETT, R.M. et al. 1985. DNA binding to human leukocytes. J. Clin. Invest. 76: 2182-2190.
11. BENNETT, R.M. et al. 1987. DNA receptor dysfunction in systemic lupus erythematosus and kindred disorders. J. Exp. Med. 166: 850-863.
12. LAKTIONOV, P. et al., inventors; Laktionov, P. & V. Vlassov, assignees. 2002. Russian patent 2002126328. Date of application: October 2.
13. LAKTIONOV, P. et al., inventors; LAKTIONOV, P. & V. VLASSOV, assignees. 2002. Russian patent 20022134341. Date of application: December 19.
14. MOROZKIN, E. et al. 2003. Fluorometric quantification of RNA and DNA in solutions containing both nucleic acids. Anal. Biochem. 322: 48-50.
15. MATRISIAN, L.M. et al. 2003. Extracellular proteolysis and cancer: meeting summery and future directions. Cancer Res. 63: 6105-6109.
16. SCHMITT, M. et al. 1991. Biological and clinical relevance of the urokinase-type plasminogen activator (uPA) in breast cancer. Biomed. Biochim. Acta 50: 731-741.
17. CHITRABAMRUNG, S. et al. 1981. A radial diffusion assay for plasma and serum deoxyribonuclease I. Rheumatol. Int. 1: 49-53.
18. PRINCE, W. et al. 1998. Pharmacodynamics of recombinant human DNase I in serum. Clin. Exp. Immunol. 113: 289-296.
19. DELIGEZER, U. et al. 2003. Frequent copresence of methylated DNA and fragmented nucleosomal DNA in plasma of lymphoma patients. Clin. Chim. Acta 335: 89-94.