Mismatch repair protein deficiency compromises cisplatin-induced apoptotic signaling

Journal of Biological Chemistry

Volumn 284, Issue 21, 2009, Pages 14029-14039

  Topping, Ryan P ^a   Wilkinson, John C ^a   Scarpinato, Drotschmann ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC SIGNALING; CASPASE; CASPASE-3; CASPASES; CHEMICAL INHIBITION; CHEMOTHERAPEUTIC DRUGS; CIS-PLATIN; CLINICAL RESPONSE; CYTOCHROME C; DNA ADDUCTS; DNA DAMAGES; IN-CELL; MISMATCH REPAIR; MOLECULAR EVENTS; P53 PROTEIN; POLY POLYMERASE; RE-LOCALIZATION; RESPONSE PATHWAYS; SIGNALING MECHANISMS;

CELL DEATH; DNA; GENES; NUCLEIC ACIDS; PLATINUM COMPOUNDS; PROTEINS; SIGNALING;

CYTOTOXICITY;

CASPASE 3; CASPASE 9; CISPLATIN; CYTOCHROME C; MISMATCH REPAIR PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P53; DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MSH2 PROTEIN, HUMAN; PROTEIN MSH2; PROTEINASE INHIBITOR;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; CYTOPLASM; ENDOMETRIUM CARCINOMA; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION; CELL SURVIVAL; DRUG ANTAGONISM; DRUG EFFECT; IC 50; METABOLISM; MISMATCH REPAIR; PROTEIN TRANSPORT; TUMOR CELL LINE;

APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; CYTOCHROMES C; CYTOPLASM; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; MUTS HOMOLOG 2 PROTEIN; POLY(ADP-RIBOSE) POLYMERASES; PROTEASE INHIBITORS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 67649784587     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M809303200     Document Type: Article

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