Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 547, Issue 1-2, 2004, Pages 71-78

  Lee, Hsin Chen ^a,b   Li, Shu Hui ^a   Lin, Jin Ching ^c   Wu, Cheng Chung ^c   Yeh, Dah Cherg ^c   Wei, Yau Huei ^b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Copy number; Hepatocellular carcinoma; Mitochondrial DNA; mtDNA; nDNA; np; Nuclear DNA; Nucleotide position; PCR; Polymerase chain reaction; Reactive oxygen species; ROS; Somatic mutation

Indexed keywords

MITOCHONDRIAL DNA; NUCLEOTIDE; POLYCYTIDYLIC ACID;

ARTICLE; CONTROLLED STUDY; DNA REPLICATION ORIGIN; DNA SEQUENCE; DNA STRAND; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; POINT MUTATION; PRIORITY JOURNAL; SOMATIC MUTATION;

BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CONSERVED SEQUENCE; DNA, MITOCHONDRIAL; GENE DOSAGE; HUMANS; LIVER NEOPLASMS; MUTATION; POINT MUTATION; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION;

EID: 1542345767     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2003.12.011     Document Type: Article

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