Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells

Oncogene

Volumn 29, Issue 27, 2010, Pages 3964-3976

  Favre, C ^a   Zhdanov, A ^a   Leahy, M ^a   Papkovsky, D ^a   O'Connor, R ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

EMT in cancer; IGF I; metabolism; mitochondria; PNC1; ROS

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; PYRIMIDINE NUCLEOTIDE CARRIER 1; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CANCER CELL; CANCER INHIBITION; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL INVASION; CELL METABOLISM; CELL PROTECTION; CELL STRAIN MCF 7; CELL TRANSFORMATION; EPITHELIAL MESENCHYMAL TRANSITION; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOFLUORESCENCE; MITOCHONDRIAL DNA REPLICATION; MITOCHONDRIAL GENE; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PHENOTYPE; PLASMID; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL NUCLEUS; CELL RESPIRATION; DNA REPLICATION; DNA, MITOCHONDRIAL; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOLYSIS; HELA CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MESODERM; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEOPLASM INVASIVENESS; NEOPLASMS; NUCLEOTIDE TRANSPORT PROTEINS; PHENOTYPE; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

EID: 77954542997     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.146     Document Type: Article

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