Cancer cell mitochondria confer apoptosis resistance and promote metastasis

Cancer Biology and Therapy

Volumn 8, Issue 14, 2009, Pages 1378-1385

  Kulawiec, Mariola ^a   Owens, Kjerstin M ^a   Singh, Keshav K ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

AKT; Apoptosis; Breast tumor; Cybrids; Metastasis; Mitochondria; Mitochondrial DNA; Transmitochondrial; 0 cells

Indexed keywords

CASPASE 3; ETOPOSIDE; MITOCHONDRIAL DNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSFER RNA; AKT1 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; TUMOR PROTEIN;

ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER RESISTANCE; CARCINOGENESIS; CELL MUTANT; CONTROLLED STUDY; CYBRID; DNA SEQUENCE; ENZYME ACTIVATION; GENE MUTATION; LUNG METASTASIS; METASTASIS; MITOCHONDRIAL GENOME; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; ADENOCARCINOMA; ANIMAL; BREAST TUMOR; CANCER TRANSPLANTATION; FEMALE; GENETICS; HUMAN; HYBRID CELL; LUNG TUMOR; METABOLISM; MISSENSE MUTATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; TRANSPLANTATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA; ANIMALS; APOPTOSIS; BREAST NEOPLASMS; DNA, MITOCHONDRIAL; FEMALE; HUMANS; HYBRID CELLS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, SCID; MITOCHONDRIA; MUTATION, MISSENSE; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SEQUENCE ANALYSIS, DNA;

EID: 76249097338     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.14.8751     Document Type: Article

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