Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol γ

EMBO Journal

Volumn 24, Issue 19, 2005, Pages 3482-3492

  Achanta, Geetha ^a   Sasaki, Ryohei ^a,b   Feng, Li ^a   Carew, Jennifer S ^a   Lu, Weiqin ^a   Pelicano, Helene ^a   Keating, Michael J ^a   Huang, Peng ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

DNA polymerase ; Mitochondria; Mutation; p53; Reactive oxygen species (ROS)

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DNA DAMAGE; DNA DEGRADATION; DNA REPLICATION; DNA STRAND BREAKAGE; GENE TRANSLOCATION; GENETIC HETEROGENEITY; GENETIC STABILITY; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; INDUCED MUTATION; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL GENETICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TUMOR SUPPRESSOR GENE; WILD TYPE;

CELL LINE, TUMOR; DNA DAMAGE; DNA PRIMERS; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; GENOMIC INSTABILITY; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MUTATION; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 27144488229     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600819     Document Type: Article

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