The prion protein unstructured N-terminal region is a broad-spectrum molecular sensor with diverse and contrasting potential functions

Journal of Neurochemistry

Volumn 120, Issue 6, 2012, Pages 853-868

  Béland, Maxime ^a   Roucou, Xavier ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Endocytosis; Intrinsically unstructured; Neurotoxicity; Prion protein; sheet

Indexed keywords

AMYLOID BETA PROTEIN; CUPRIC ION; DNA; HEMIN; HEPARAN SULFATE; NUCLEIC ACID; PRION PROTEIN; RECOMBINANT PRION PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; DNA TRANSFER; ENDOCYTOSIS; EXTRACELLULAR SPACE; GENE DELETION; HUMAN; LIGAND BINDING; METAL BINDING; MOLECULAR SENSOR; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

EID: 84857834839     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07613.x     Document Type: Review

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