Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125

EMBO Journal

Volumn 26, Issue 2, 2007, Pages 548-558

  Li, Aimin ^a   Christensen, Heather M ^a   Stewart, Leanne R ^a   Roth, Kevin A ^b   Chiesa, Roberto ^c   Harris, David A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Lethal; Neurodegeneration; Prion; Transgenic

Indexed keywords

AMINO ACID; PRION PROTEIN; PROTEIN DERIVATIVE; PROTEIN DOPPEL; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENGINEERING; BIRTH; CENTRAL NERVOUS SYSTEM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENE DELETION; GENE OVEREXPRESSION; HYPOTHESIS; LETHALITY; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NEWBORN MORTALITY; NONHUMAN; PHENOTYPE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CELLS, CULTURED; GENE DELETION; GENES, LETHAL; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; MODELS, BIOLOGICAL; PRPC PROTEINS;

MURINAE; MUS; MUS MUSCULUS;

EID: 33846543360     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601507     Document Type: Article

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