-
1
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
Consortium
-
Consortium Finishing the euchromatic sequence of the human genome Nature 431 2004 931 945
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
2
-
-
0035058360
-
Evolution of genome size: New approaches to an old problem
-
D.A. Petrov Evolution of genome size: new approaches to an old problem Trends Genet. 17 2001 23 28
-
(2001)
Trends Genet.
, vol.17
, pp. 23-28
-
-
Petrov, D.A.1
-
3
-
-
0141867857
-
Challenging the dogma: The hidden layer of non-protein-coding RNAs in complex organisms
-
J.S. Mattick Challenging the dogma: the hidden layer of non-protein-coding RNAs in complex organisms Bioessays 25 2003 930 939
-
(2003)
Bioessays
, vol.25
, pp. 930-939
-
-
Mattick, J.S.1
-
5
-
-
0037235543
-
Multifunctional proteins: Examples of gene sharing
-
C.J. Jeffery Multifunctional proteins: examples of gene sharing Ann. Med. 35 2003 28 35
-
(2003)
Ann. Med.
, vol.35
, pp. 28-35
-
-
Jeffery, C.J.1
-
6
-
-
9944225262
-
Molecular mechanisms for multitasking: Recent crystal structures of moonlighting proteins
-
C.J. Jeffery Molecular mechanisms for multitasking: recent crystal structures of moonlighting proteins Curr. Opin. Struct. Biol. 14 2004 663 668
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 663-668
-
-
Jeffery, C.J.1
-
7
-
-
0032749078
-
Intrinsically unstructured proteins: Re-assessing the protein structure-function paradigm
-
P.E. Wright, and H.J. Dyson Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm J. Mol. Biol. 293 1999 321 331
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 321-331
-
-
Wright, P.E.1
Dyson, H.J.2
-
8
-
-
0036803243
-
Intrinsically unstructured proteins
-
P. Tompa Intrinsically unstructured proteins Trends Biochem. Sci. 27 2002 527 533
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 527-533
-
-
Tompa, P.1
-
9
-
-
0037188377
-
Intrinsic disorder and protein function
-
A.K. Dunker Intrinsic disorder and protein function Biochemistry 41 2002 6573 6582
-
(2002)
Biochemistry
, vol.41
, pp. 6573-6582
-
-
Dunker, A.K.1
-
10
-
-
13844255387
-
Natively unfolded proteins
-
A.L. Fink Natively unfolded proteins Curr. Opin. Struct. Biol. 15 2005 35 41
-
(2005)
Curr. Opin. Struct. Biol.
, vol.15
, pp. 35-41
-
-
Fink, A.L.1
-
11
-
-
14644435825
-
Intrinsically unstructured proteins and their functions
-
H.J. Dyson, and P.E. Wright Intrinsically unstructured proteins and their functions Nat. Rev. Mol. Cell Biol. 6 2005 197 208
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 197-208
-
-
Dyson, H.J.1
Wright, P.E.2
-
12
-
-
0036408751
-
Intrinsic disorder in cell-signaling and cancer-associated proteins
-
L. Iakoucheva Intrinsic disorder in cell-signaling and cancer-associated proteins J. Mol. Biol. 323 2002 573 584
-
(2002)
J. Mol. Biol.
, vol.323
, pp. 573-584
-
-
Iakoucheva, L.1
-
13
-
-
1542358787
-
Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
-
J.J. Ward Prediction and functional analysis of native disorder in proteins from the three kingdoms of life J. Mol. Biol. 337 2004 635 645
-
(2004)
J. Mol. Biol.
, vol.337
, pp. 635-645
-
-
Ward, J.J.1
-
14
-
-
3442902456
-
The role of structural disorder in the function of RNA and protein chaperones
-
P. Tompa, and P. Csermely The role of structural disorder in the function of RNA and protein chaperones FASEB J. 18 2004 1169 1175
-
(2004)
FASEB J.
, vol.18
, pp. 1169-1175
-
-
Tompa, P.1
Csermely, P.2
-
15
-
-
0029662315
-
Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: Conformational disorder mediates binding diversity
-
R.W. Kriwacki Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity Proc. Natl. Acad. Sci. U. S. A. 93 1996 11504 11509
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 11504-11509
-
-
Kriwacki, R.W.1
-
16
-
-
0033574614
-
Mechanisms of cyclin-dependent kinase regulation: Structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
-
N.P. Pavletich Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors J. Mol. Biol. 287 1999 821 828
-
(1999)
J. Mol. Biol.
, vol.287
, pp. 821-828
-
-
Pavletich, N.P.1
-
17
-
-
0033559264
-
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
-
M. Cheng The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts EMBO J. 18 1999 1571 1583
-
(1999)
EMBO J.
, vol.18
, pp. 1571-1583
-
-
Cheng, M.1
-
18
-
-
0037662824
-
The random-coil 'C' fragment of the dihydropyridine receptor II-III loop can activate or inhibit native skeletal ryanodine receptors
-
C.S. Haarmann The random-coil 'C' fragment of the dihydropyridine receptor II-III loop can activate or inhibit native skeletal ryanodine receptors Biochem. J. 372 2003 305 316
-
(2003)
Biochem. J.
, vol.372
, pp. 305-316
-
-
Haarmann, C.S.1
-
19
-
-
23044518337
-
Stimulatory and inhibitory functions of the R domain on CFTR chloride channel
-
J. Ma Stimulatory and inhibitory functions of the R domain on CFTR chloride channel News Physiol. Sci. 15 2000 154 158
-
(2000)
News Physiol. Sci.
, vol.15
, pp. 154-158
-
-
Ma, J.1
-
20
-
-
3242709056
-
Cell cycle control: A complex issue
-
N. Olashaw Cell cycle control: a complex issue Cell Cycle 3 2004 263 264
-
(2004)
Cell Cycle
, vol.3
, pp. 263-264
-
-
Olashaw, N.1
-
21
-
-
1842473094
-
P27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding
-
E.R. Lacy p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding Nat. Struct. Mol. Biol. 11 2004 358 364
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 358-364
-
-
Lacy, E.R.1
-
22
-
-
0028169236
-
P21-containing cyclin kinases exist in both active and inactive states
-
H. Zhang p21-containing cyclin kinases exist in both active and inactive states Genes Dev. 8 1994 1750 1758
-
(1994)
Genes Dev.
, vol.8
, pp. 1750-1758
-
-
Zhang, H.1
-
23
-
-
0037088661
-
Calpastatin subdomains a and C are activators of calpain
-
P. Tompa Calpastatin subdomains A and C are activators of calpain J. Biol. Chem. 277 2002 9022 9026
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9022-9026
-
-
Tompa, P.1
-
24
-
-
0038198603
-
Caspase-1-induced calpastatin degradation in myoblast differentiation and fusion: Cross-talk between the caspase and calpain systems
-
S. Barnoy, and N.S. Kosower Caspase-1-induced calpastatin degradation in myoblast differentiation and fusion: cross-talk between the caspase and calpain systems FEBS Lett. 546 2003 213 217
-
(2003)
FEBS Lett.
, vol.546
, pp. 213-217
-
-
Barnoy, S.1
Kosower, N.S.2
-
25
-
-
1642533607
-
The functional benefits of protein disorder
-
P. Tompa The functional benefits of protein disorder J. Mol. Struct. THEOCHEM 666-667 2003 361 371
-
(2003)
J. Mol. Struct. THEOCHEM
, vol.666-667
, pp. 361-371
-
-
Tompa, P.1
-
26
-
-
0034725628
-
Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif
-
J. Yang Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif J. Biol. Chem. 275 2000 22635 22644
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 22635-22644
-
-
Yang, J.1
-
27
-
-
0028865511
-
Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1
-
H.Y. Tung Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1 Mol. Cell. Biol. 15 1995 6064 6074
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6064-6074
-
-
Tung, H.Y.1
-
28
-
-
0035906989
-
Securin is required for chromosomal stability in human cells
-
P.V. Jallepalli Securin is required for chromosomal stability in human cells Cell 105 2001 445 457
-
(2001)
Cell
, vol.105
, pp. 445-457
-
-
Jallepalli, P.V.1
-
29
-
-
0037172655
-
The dual mechanism of separase regulation by securin
-
N.C. Hornig The dual mechanism of separase regulation by securin Curr. Biol. 12 2002 973 982
-
(2002)
Curr. Biol.
, vol.12
, pp. 973-982
-
-
Hornig, N.C.1
-
30
-
-
1542390384
-
Separase regulation during mitosis
-
F. Uhlmann Separase regulation during mitosis Biochem. Soc. Symp. 70 2003 243 251
-
(2003)
Biochem. Soc. Symp.
, vol.70
, pp. 243-251
-
-
Uhlmann, F.1
-
31
-
-
0037675852
-
Mutual induced fit binding of Xenopus ribosomal protein L5 to 5S rRNA
-
J.P. DiNitto, and P.W. Huber Mutual induced fit binding of Xenopus ribosomal protein L5 to 5S rRNA J. Mol. Biol. 330 2003 979 992
-
(2003)
J. Mol. Biol.
, vol.330
, pp. 979-992
-
-
Dinitto, J.P.1
Huber, P.W.2
-
32
-
-
7244238177
-
Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5
-
M.S. Dai, and H. Lu Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5 J. Biol. Chem. 279 2004 44475 44482
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44475-44482
-
-
Dai, M.S.1
Lu, H.2
-
33
-
-
0032555233
-
The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression
-
V. Ruvolo The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression Proc. Natl. Acad. Sci. U. S. A. 95 1998 8852 8857
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 8852-8857
-
-
Ruvolo, V.1
-
34
-
-
1942437554
-
MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53
-
Z. Zhang MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53 J. Biol. Chem. 279 2004 16000 16006
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16000-16006
-
-
Zhang, Z.1
-
35
-
-
0034810227
-
MDM2 enhances the function of estrogen receptor α in human breast cancer cells
-
S. Saji MDM2 enhances the function of estrogen receptor α in human breast cancer cells Biochem. Biophys. Res. Commun. 281 2001 259 265
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.281
, pp. 259-265
-
-
Saji, S.1
-
36
-
-
2542492280
-
Coupling of folding and binding of thymosin β4 upon interaction with monomeric actin monitored by nuclear magnetic resonance
-
M. Domanski Coupling of folding and binding of thymosin β4 upon interaction with monomeric actin monitored by nuclear magnetic resonance J. Biol. Chem. 279 2004 23637 23645
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23637-23645
-
-
Domanski, M.1
-
37
-
-
9644281738
-
Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
-
I. Bock-Marquette Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair Nature 432 2004 466 472
-
(2004)
Nature
, vol.432
, pp. 466-472
-
-
Bock-Marquette, I.1
-
38
-
-
0037177848
-
Control of actin dynamics by proteins made of β-thymosin repeats: The actobindin family
-
M. Hertzog Control of actin dynamics by proteins made of β-thymosin repeats: the actobindin family J. Biol. Chem. 277 2002 14786 14792
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14786-14792
-
-
Hertzog, M.1
-
39
-
-
2542421811
-
The β-thymosin/WH2 domain; Structural basis for the switch from inhibition to promotion of actin assembly
-
M. Hertzog The β-thymosin/WH2 domain; structural basis for the switch from inhibition to promotion of actin assembly Cell 117 2004 611 623
-
(2004)
Cell
, vol.117
, pp. 611-623
-
-
Hertzog, M.1
-
40
-
-
0034624877
-
Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction
-
J. Liao Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction Proc. Natl. Acad. Sci. U. S. A. 97 2000 5267 5272
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5267-5272
-
-
Liao, J.1
-
41
-
-
0037041024
-
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
-
T. Megidish Activation of p53 by protein inhibitor of activated Stat1 (PIAS1) J. Biol. Chem. 277 2002 8255 8259
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8255-8259
-
-
Megidish, T.1
-
42
-
-
0031578217
-
Cloning and characterization of Gu/RH-II binding protein
-
B.C. Valdez Cloning and characterization of Gu/RH-II binding protein Biochem. Biophys. Res. Commun. 234 1997 335 340
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.234
, pp. 335-340
-
-
Valdez, B.C.1
-
43
-
-
0038094496
-
Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II
-
C. Fabrega Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II Mol. Cell 11 2003 1549 1561
-
(2003)
Mol. Cell
, vol.11
, pp. 1549-1561
-
-
Fabrega, C.1
-
44
-
-
11144341950
-
Substrate recognition strategy for botulinum neurotoxin serotype a
-
M.A. Breidenbach, and A.T. Brunger Substrate recognition strategy for botulinum neurotoxin serotype A Nature 432 2004 925 929
-
(2004)
Nature
, vol.432
, pp. 925-929
-
-
Breidenbach, M.A.1
Brunger, A.T.2
-
45
-
-
0032956071
-
CFTR is a conductance regulator as well as a chloride channel
-
E.M. Schwiebert CFTR is a conductance regulator as well as a chloride channel Physiol. Rev. 79 1999 S145 S166
-
(1999)
Physiol. Rev.
, vol.79
-
-
Schwiebert, E.M.1
-
46
-
-
0037050026
-
Functional organization of the yeast proteome by systematic analysis of protein complexes
-
A.C. Gavin Functional organization of the yeast proteome by systematic analysis of protein complexes Nature 415 2002 141 147
-
(2002)
Nature
, vol.415
, pp. 141-147
-
-
Gavin, A.C.1
-
47
-
-
0038148710
-
Conformational diversity and protein evolution - A 60-year-old hypothesis revisited
-
L.C. James, and D.S. Tawfik Conformational diversity and protein evolution - a 60-year-old hypothesis revisited Trends Biochem. Sci. 28 2003 361 368
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 361-368
-
-
James, L.C.1
Tawfik, D.S.2
-
48
-
-
14844342815
-
The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins
-
Z. Dosztányi The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins J. Mol. Biol. 347 2005 827 839
-
(2005)
J. Mol. Biol.
, vol.347
, pp. 827-839
-
-
Dosztányi, Z.1
-
49
-
-
0032735680
-
Thymosin β4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids
-
J.D. Young Thymosin β4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids Nat. Med. 5 1999 1424 1427
-
(1999)
Nat. Med.
, vol.5
, pp. 1424-1427
-
-
Young, J.D.1
|