Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

EMBO Journal

Volumn 21, Issue 13, 2002, Pages 3307-3316

  Zanata, Silvio M ^a   Lopes, Marilene H ^a   Mercadante, Adriana F ^a   Hajj, Glaucia N M ^a   Chiarini, Luciana B ^a   Nomizo, Regina ^a   Freitas, Adriana R O ^a   Cabral, Ana L B ^a   Lee, Kil S ^a   Juliano, Maria A ^a   De Oliveira, Elizabeth ^a   Jachieri, Saul G ^a   Burlingame, Alma ^a   Huang, Lan ^a   Linden, Rafael ^a   Brentani, Ricardo R ^a   Martins, Vilma R ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Brazil)

Author keywords

Neuroprotection; Prion; PrPc PrPc ligand; Stress inducible protein

Indexed keywords

CELL SURFACE PROTEIN; PRION PROTEIN; SIALOGLYCOPROTEIN; STRESS INDUCIBLE PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CELL SURFACE; CONTROLLED STUDY; IMMUNOPRECIPITATION; LIGAND BINDING; MEMBRANE BINDING; MOUSE; NEUROPROTECTION; NONHUMAN; PRION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; WESTERN BLOTTING;

ANIMALS; ANISOMYCIN; APOPTOSIS; BINDING SITES; COPPER; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EYE PROTEINS; HEAT-SHOCK PROTEINS; HYDROPHOBICITY; LAMININ; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MICE; MOLECULAR CHAPERONES; NERVE TISSUE PROTEINS; NEURONS; ORGAN CULTURE TECHNIQUES; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PRPC PROTEINS; RECOMBINANT FUSION PROTEINS; RETINA; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 18444397736     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf325     Document Type: Article

References (68)

1. Prion research: The next frontiers
2. Structure and function of laminin: Anatomy of a multidomain glycoprotein
3. Molecular characterization of extendin: A protein localized in extending pseudopodia
4. Isolation of a mouse cDNA encoding mSTI1, a stress-inducible protein containing the TPR motif
5. Is hydropathic complementarity involved in antigen-antibody binding?
6. Similarity between the corticotropin (ACTH) receptor and a peptide encoded by an RNA that is complementary to ACTH mRNA
7. Biological implications of complementary hydropathy of amino acids
8. The cellular prion protein binds copper in vivo
9. Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
10. Normal prion protein has an activity like that of superoxide dismutase
11. Normal development and behaviour of mice lacking the neuronal cellsurface PrP protein
12. Mice devoid of PrP are resistant to scrapie
13. Formation of the 67-kDa laminin receptor by acylation of the precursor
14. c gene expression depends on chromatin conformation
15. Cellular prion protein transduces neuroprotective signals
16. Role of accurate mass measurement (±10 p.p.m.) in protein identification strategies employing MS or MS/MS and database searching
17. Prion dementia without characteristic pathology
18. Collagen binding site in collagenase can be determined using the concept of sense-antisense peptide interactions
19. Neurotoxicity of a prion protein fragment
20. The 37 kDa/67 kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein
21. Two-dimensional polyacrylamide gel electrophoresis with immobilized pH gradients in the first dimension (IPG-Dalt): The state of art and the controversy of vertical versus horizontal systems
22. Cellular prion protein binds laminin and mediates neuritogenesis
23. Laminin-induced PC-12 cell differentiation is inhibited following laser inactivation of cellular prion protein
24. An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II
25. Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress-inducible yeast protein STI1
26. Identification and isolation of three proteasome subunits and their encoding genes from Trypanosoma brucei
27. Identification of interaction domains of the prion protein with its 37 kDa/67 kDa laminin receptor
28. The cellular prion protein colocalizes with the dystroglycan complex in the brain
29. Function of PrP(C) as a copper-binding protein at the synapse
30. Prions prevent neuronal cell-line death
31. Stress-inducible, murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases
32. Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells
33. Internalization of a mammalian fluorescent prion protein involves classical endocytic organelles
34. The in vitro phosphorylation of the co-chaperone mSTI1 by cell cycle kinases substantiates a predicted casein kinase II-p34cdc2-NLS (CcN) motif
35. De novo generation of a PrPSc-like conformation in living cells
36. Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation
37. Infection by Trypanosoma cruzi. Identification of a parasite ligand and its host cell receptor
38. Complementary hydropathy identifies a cellular prion protein receptor
39. Insights into the physiological function of cellular prion protein
40. Cellular prion protein: On the road for functions
41. Fatal familial insomnia: A second kindred with mutation of prion protein gene at codon 178
42. Bovine prion protein as a modulator of protein kinase CK2
43. Actin is a surface component of calf pulmonary artery endothelial cells in culture
44. Signal transduction through prion protein
45. A novel pathway for secretory proteins?
46. Susceptibility of the prion protein to enzymic phosphorylation
47. Copper stimulates endocytosis of the prion protein
48. Prions
49. Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension
50. Selective sensitivity of early postmitotic retinal cells to apoptosis induced by inhibition of protein synthesis
51. The human 37-kDa laminin receptor precursor interacts with the prion protein in eukariotic cells
52. Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A
53. Can loss-of-function prion-related diseases exist?
54. A prion-linked psychiatric disorder
55. The attraction of proteins for small molecules and ions
56. Contact activation: A revision
57. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion prolein
58. Prion protein gene expression in cultured cells
59. A protein partially expressed on the surface of HepG2 cells that binds lipoproteins specifically is nucleolin
60. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
61. Induced release of cell surface protein kinase yields CK1- and CK2-like enzymes in tandem
62. Increased sensitivity to seizures in mice lacking cellular prion protein
63. Cytokeratin 18 is expressed on the hepatocyte plasma membrane surface and interacts with thrombin-antithrombin complexes
64. Copper refolding of prion protein
65. Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein
66. Human prion proteins expressed in Escherichic coli and purified by high-affinity column refolding
67. Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in semaphorin 3A-induced cytoskeletal collapse