Glypican-1 mediates both prion protein lipid raft association and disease isoform formation

PLoS Pathogens

Volumn 5, Issue 11, 2009, Pages

  Taylor, David R ^a   Whitehouse, Isobel J ^a   Hooper, Nigel M ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GLYPICAN 1; HEPARIN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL LYASE; PRION PROTEIN; PROTEOHEPARAN SULFATE; SMALL INTERFERING RNA; AMYLOID; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; GLYPICAN; ISOPROTEIN; SECRETASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; ENDOCYTOSIS; ENZYME INHIBITION; IMMUNOPRECIPITATION; LIPID RAFT; MOUSE; NONHUMAN; PRION DISEASE; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SCRAPIE; ANIMAL; CELL MEMBRANE; DISEASE MODEL; DRUG EFFECT; METABOLISM; PRION; TUMOR CELL LINE;

AMYLOID; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; CELL LINE, TUMOR; CELL MEMBRANE; DISEASE MODELS, ANIMAL; GLYPICANS; HEPARIN; MEMBRANE MICRODOMAINS; MICE; PRION DISEASES; PRIONS; PROTEIN ISOFORMS; PRPC PROTEINS; PRPSC PROTEINS;

EID: 73549083896     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000666     Document Type: Article

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