Unexpected tolerance of α-cleavage of the prion protein to sequence variations

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Oliveira Martins, José B ^a   Yusa, Sei Ichi ^a   Calella, Anna Maria ^a   Bridel, Claire ^a   Baumann, Frank ^a   Dametto, Paolo ^a   Aguzzi, Adriano ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GLYCINE; MUTANT PROTEIN; PRION PROTEIN; PEPTIDE HYDROLASE; PRNP PROTEIN, MOUSE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MOUSE; NEUROTOXICITY; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; ANIMAL; BINDING SITE; CELL LINE; CELL STRAIN 3T3; CHEMISTRY; GENETICS; GLYCOSYLATION; HELA CELL; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; MUTATION; PRION; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

MUS MUSCULUS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CELL LINE; GLYCOSYLATION; HELA CELLS; HUMANS; HYDROPHOBICITY; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUTATION; NIH 3T3 CELLS; PEPTIDE HYDROLASES; PRIONS; PRPC PROTEINS; PRPSC PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 77949405435     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009107     Document Type: Article

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