Glycosaminoglycans and β-amyloid, prion and tau peptides in neurodegenerative diseases

Peptides

Volumn 23, Issue 7, 2002, Pages 1323-1332

  Díaz Nido, Javier ^a   Wandosell, Francisco ^a   Avila, Jesús ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Alzheimer's disease; Amyloid peptide; Neurodegenerative disease; Neurofibrillary tangle; Neuroprotection; Neurotoxicity; Prion disease; Protein aggregation; Proteoglycan; Spongiform encephalopathy; Sulfated glycosaminoglycan; Tau protein; Tauopathy

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE; CHONDROITIN; GAMMA SECRETASE; GLYCOSAMINOGLYCAN POLYSULFATE; HEPARAN SULFATE; HYALURONIC ACID; PENTOSAN POLYSULFATE; PRION PROTEIN; PROTEOGLYCAN; TAU PROTEIN; GLYCOSAMINOGLYCAN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BRAIN SPONGIOSIS; DEGENERATIVE DISEASE; HUMAN; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; SENILE PLAQUE; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; METABOLISM; PATHOLOGY; PRION; PROTEIN CONFORMATION; PROTEIN PROCESSING; REVIEW;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; GLYCOSAMINOGLYCANS; HUMANS; MODELS, BIOLOGICAL; NEURODEGENERATIVE DISEASES; NEUROFIBRILLARY TANGLES; PRIONS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SENILE PLAQUES; TAU PROTEINS;

EID: 0035997236     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(02)00068-2     Document Type: Review

References (116)

1. Does the agent of scrapie replicate without nucleic acid?
2. Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration
3. Prion rods contain an inert polysaccharide scaffold
4. Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations
5. Role of glycosaminoglycans in determining the helicity of paired helical filaments
6. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
7. Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo Red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent
8. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
9. Characterization and polyanion-binding properties of purified recombinant prion protein
10. Mise en evidence immunologique de la proteine tau an niveau des lesions degenerescence neurofibrillaire de la maladie d'Alzheimer
11. Prion protein peptides: Optimal toxicity and peptide blockade of toxicity
12. Perineuronal nets provide a polyanionic, glia-associated form of microenvironment around certain neurons in many parts of the rat brain
13. Cortical areas abundant in extracellular matrix chondroitin sulphate proteoglycans are less affected by cytoskeletal changes in Alzheimer's disease
14. Cortical areas are revealed by distribution patterns of proteoglycan components and parvalbumin in the Mongolian gerbil and rat
15. β-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding
16. Molecular modeling of protein-glycosaminoglycan interactions
17. The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation
18. Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and Congo Red
19. Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells
20. Scrapie associated PrP accumulation and its prevention: Insights from cell culture
21. Perineuronal nets: Past and present
22. Prion diseases of humans and animals: Their causes and molecular basis
23. Chondroitin sulfate proteoglycans are a common component of neuronal inclusions and astrocytic reaction in neurodegenerative diseases
24. Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease
25. Dextran sulphate 500 delays and prevents mouse scrapie by impairment of agent replication in spleen
26. In vivo cytotoxicity of the prion protein fragment 106-126
27. Neurotoxicity of a prion protein fragment
28. Amyloid in Alzheimer's disease and prion-related encephalopathies: Studies with synthetic peptides
29. Structure and function of proteoglycans
30. Effects of sulfate ions on Alzheimer beta/A4 peptide assemblies: Implications for amyloid fibril-proteoglycan interactions
31. Heparin-like molecules bind differentially to prion-proteins and change their intracellular metabolic fate
32. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity
33. Alzheimer's disease (senile dementia) a research update and critique with recommendations
34. Filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases
35. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
36. Filamentous nerve cell inclusions in neurodegenerative diseases
37. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: Differential expression of tau protein mRNAs in human brain
38. Filamentous nerve cell inclusions in neurodegenerative diseases: Tauopathies and alpha-synucleinopathies
39. Self-replication and scrapie
40. Microtubule-associated protein tau. A component of Alzheimer paired helical filaments
41. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
42. Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation
43. Proteoglycans: Many forms and many functions
44. Amyloid, the presenilins and Alzheimer's disease
45. Chondroitin sulfate proteoglycan-immunoreactivity of lectin-labeled perineuronal nets around parvalbumin-containing neurons
46. Hyperphosphorylated protein tau is restricted to neurons devoid of perineuronal nets in the cortex of aged bison
47. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
48. Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: Assessment of selectivity, heterogeneity and the participation of core proteins in binding
49. Accumulation of abnormal amounts of glycosaminoglycans in murine mucopolysaccharidosis type VII neural progenitor cells does not alter the growth rate or efficiency of differentiation into neurons
50. Prions and neurodegenerative diseases
51. In search of an enzyme: The beta-secretase of Alzheimer's disease is an aspartic proteinase
52. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
53. Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease
54. Alzheimer's paired helical filaments
55. Mammalian prion proteins
56. The role of microtubules in the regulation of proteoglycan synthesis in chondrocytes under hydrostatic pressure
57. A synthetic peptide initiates Gerstmann-Straussler-Scheinker (GSS) disease in transgenic mice
58. Aberrant protein deposition and neurological disease
59. Paired helical filaments in electron microscopy of Alzheimer's disease
60. Suppression of scrapie infection in mice by heteropolyanion 23, dextran sulfate, and some other polyanions
61. Proteoglycans: Structures and interactions
62. Targeting small A beta oligomers: The solution to an Alzheimer's disease conundrum?
63. Age-related modifications of MAP-2
64. High molecular weight microtubule-associated proteins: Purification by electro-elution and amino acid compositions
65. Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease
66. Proteoglycans in the nervous system
67. A family of activity-dependent neuronal cell-surface chondroitin sulfate proteoglycans in cat visual cortex
68. Following nature's anti-amyloid strategy
69. Regulated diversity of heparan sulfate
70. On the nucleation and growth of amyloid beta-protein fibrils: Detection of nuclei and quantitation of rate constants
71. Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: Mapping of ligand binding and GAG attachment sites
72. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by Congo Red
73. Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor
74. Aggrecan-versican-neurocan family proteoglycans
75. Amyloid plaque core protein in Alzheimer disease and Down syndrome
76. Effect of amino-acid substitutions on Alzheimer's amyloid-beta peptide-glycosaminoglycan interactions
77. Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease
78. Oligosaccharide transport: Pumping waste from the ER into lysosomes
79. A modified form of microtubule-associated tau protein is the main component of paired helical filaments
80. Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome
81. Effects of lipid-derivatized glycosaminoglycans (GAGs), a novel probe for functional analyses of GAGs, on cell-to-substratum adhesion and neurite elongation in primary cultures of fetal rat hippocampal neurons
82. The chondroitin sulfate attachment site of appican is formed by splicing out exon 15 of the amyloid precursor gene
83. Cell surface heparan sulfate proteoglycans: Selective regulators of ligand-receptor encounters
84. Polymerization of tau into filaments in the presence of heparin: The minimal sequence required for tau-tau interaction
85. Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment
86. Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton
87. Neurodegeneration induced by beta-amyloid peptides in vitro: The role of peptide assembly state
88. Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of beta-amyloid in rat PC12 cells
89. Neurotoxicity but not infectivity of prion proteins can be induced reversibly in vitro
90. Novel proteinaceous infectious particles cause scrapie
91. Prion diseases and the BSE crisis
92. Synthesis and sorting of proteoglycans
93. Brain extracellular matrix
94. Translating cell biology into therapeutic advances in Alzheimer's disease
95. Reconstitution of prion infectivity from solubilized protease-resistant PrP and non-protein components of prion rods
96. c, in cultured cells
97. Role of proteoglycans in neural development, regeneration, and the aging brain
98. A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth
99. The role of heparan sulfate proteoglycans in the pathogenesis of Alzheimer's disease
100. The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease
101. An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain
102. Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie
103. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
104. Scrapie prion protein contains a phosphatidylinositol glycolipid
105. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
106. A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Straussler-Scheinker disease A117V
107. Dynamic regulation of expression and phosphorylation of tau by fibroblast growth factor-2 in neural progenitor cells from adult rat hippocampus
108. Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126
109. Aβ amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice
110. Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
111. Structural characterization of the core of the paired helical filament of Alzheimer disease
112. Sulfated glycans and elevated temperature stimulate PrP (sc)-dependent cell-free formation of protease-resistant prion protein
113. Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)
114. Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate beta-amyloid (25-35) induced neurodegeneration in cultured hippocampal neurons
115. Mechanisms of neuronal degeneration in Alzheimer's disease