Assigning functions to distinct regions of the N-terminus of the prion protein that are involved in its copper-stimulated, clathrin-dependent endocytosis

Journal of Cell Science

Volumn 118, Issue 21, 2005, Pages 5141-5153

  Taylor, David R ^a   Watt, Nicole T ^a   Perera, W Sumudhu S ^a   Hooper, Nigel M ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Clathrin; Copper; Endocytosis; Lipid rafts; Prion protein

Indexed keywords

ADAPTOR PROTEIN; CLATHRIN; COPPER; MEMBRANE PROTEIN; MUTANT PROTEIN; PRION PROTEIN; TRITON X 100; TYROSINE; TYRPHOSTIN;

AMINO TERMINAL SEQUENCE; ARTICLE; ASSAY; BIOTINYLATION; CONTROLLED STUDY; DISSOCIATION; ENDOCYTOSIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTERNALIZATION; LIPID RAFT; METAL BINDING; NERVE CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SUCROSE DENSITY GRADIENT CENTRIFUGATION;

ANIMALS; BINDING SITES; CELL LINE, TUMOR; CLATHRIN; COPPER; DETERGENTS; ENDOCYTOSIS; HUMANS; MEMBRANE MICRODOMAINS; MICE; MONOMERIC CLATHRIN ASSEMBLY PROTEINS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN TRANSPORT; PRPC PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; SOLUBILITY; TRANSFECTION; TYRPHOSTINS;

EID: 27944486535     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02627     Document Type: Article

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