Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and Swedish mutant amyloid precursor protein

Journal of Biological Chemistry

Volumn 286, Issue 38, 2011, Pages 33489-33500

  Griffiths, Heledd H ^a   Whitehouse, Isobel J ^a   Baybutt, Herbert ^b   Brown, Debbie ^b   Kellett, Katherine A B ^a   Jackson, Carolyn D ^a   Turner, Anthony J ^a   Piccardo, Pedro ^b,c   Manson, Jean C ^b   Hooper, Nigel M ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEINS; CELL SURFACES; CELLULAR MECHANISMS; CELLULAR MODEL; CELLULAR PRION PROTEINS; ENDOSOMES; INDIANA; MOUSE BRAIN; PRION PROTEIN; PROTEOLYTIC PROCESSING; RATE-LIMITING STEPS; SECRETASES; SUBCELLULAR LOCATION; TRANSGENIC MICE; WILD TYPES;

C (PROGRAMMING LANGUAGE); CELL MEMBRANES; DISEASE CONTROL; GLYCOPROTEINS; MAMMALS; NEURODEGENERATIVE DISEASES; OLIGOMERS;

PROTEINS;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; MUTANT PROTEIN; OLIGOMER; PRION PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVITY; ENZYME REGULATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SENILE PLAQUE; WILD TYPE;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BINDING SITES; CELL LINE; GENE DELETION; HUMANS; MALE; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PRIONS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; SUBCELLULAR FRACTIONS;

MURINAE; MUS; MUS MUSCULUS;

EID: 80052979854     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.278556     Document Type: Article

References (40)

1. Morrissette, D. A., Parachikova, A., Green, K. N., and LaFerla, F. M. (2009) J. Biol. Chem. 284, 6033-6037
2. Mullan, M., Crawford, F., Axelman, K., Houlden, H., Lilius, L., Winblad, B., and Lannfelt, L. (1992) Nat. Genet. 1, 345-347
3. Murrell, J., Farlow, M., Ghetti, B., and Benson, M. D. (1991) Science 254, 97-99
4. Selkoe, D. J. (2001) Physiol. Rev. 81, 741-766
5. Vardy, E. R., Catto, A. J., and Hooper, N. M. (2005) Trends Mol. Med. 11, 464-472
6. Cole, S. L., and Vassar, R. (2008) J. Biol. Chem. 283, 29621-29625
7. Fukumoto, H., Cheung, B. S., Hyman, B. T., and Irizarry, M. C. (2002) Arch. Neurol. 59, 1381-1389
8. Li, R., Lindholm, K., Yang, L. B., Yue, X., Citron, M., Yan, R., Beach, T., Sue, L., Sabbagh, M., Cai, H., Wong, P., Price, D., and Shen, Y. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 3632-3637
9. Vassar, R., Kovacs, D. M., Yan, R., and Wong, P. C. (2009) J. Neurosci. 29, 12787-12794
10. Parkin, E. T., Watt, N. T., Hussain, I., Eckman, E. A., Eckman, C. B., Manson, J. C., Baybutt, H. N., Turner, A. J., and Hooper, N. M. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 11062-11067
11. Hooper, N. M., and Turner, A. J. (2008) Trends Biochem. Sci. 33, 151-155
12. Whitehouse, I. J., Jackson, C., Turner, A. J., and Hooper, N. M. (2010) J. Alzheimers Dis. 22, 1023-1031
13. Bennett, B. D., Denis, P., Haniu, M., Teplow, D. B., Kahn, S., Louis, J. C., Citron, M., and Vassar, R. (2000) J. Biol. Chem. 275, 37712-37717
14. Capell, A., Steiner, H., Willem, M., Kaiser, H., Meyer, C., Walter, J., Lammich, S., Multhaup, G., and Haass, C. (2000) J. Biol. Chem. 275, 30849-30854
15. Benjannet, S., Elagoz, A., Wickham, L., Mamarbachi, M., Munzer, J. S., Basak, A., Lazure, C., Cromlish, J. A., Sisodia, S., Checler, F., Chrétien, M., and Seidah, N. G. (2001) J. Biol. Chem. 276, 10879-10887
16. Creemers, J. W., Ines Dominguez, D., Plets, E., Serneels, L., Taylor, N. A., Multhaup, G., Craessaerts, K., Annaert, W., and De Strooper, B. (2001) J. Biol. Chem. 276, 4211-4217
17. Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., Luo, Y., Fisher, S., Fuller, J., Edenson, S., Lile, J., Jarosinski, M. A., Biere, A. L., Curran, E., Burgess, T., Louis, J. C., Collins, F., Treanor, J., Rogers, G., and Citron, M. (1999) Science 286, 735-741
18. Huse, J. T., Pijak, D. S., Leslie, G. J., Lee, V. M., and Doms, R. W. (2000) J. Biol. Chem. 275, 33729-33737
19. Yan, R., Han, P., Miao, H., Greengard, P., and Xu, H. (2001) J. Biol. Chem. 276, 36788-36796
20. Haass, C., Lemere, C. A., Capell, A., Citron, M., Seubert, P., Schenk, D., Lannfelt, L., and Selkoe, D. J. (1995) Nat. Med. 1, 1291-1296
21. Thinakaran, G., Teplow, D. B., Siman, R., Greenberg, B., and Sisodia, S. S. (1996) J. Biol. Chem. 271, 9390-9397
22. Manson, J. C., Clarke, A. R., Hooper, M. L., Aitchison, L., McConnell, I., and Hope, J. (1994) Mol. Neurobiol. 8, 121-127
23. Zhao, J., Fu, Y., Yasvoina, M., Shao, P., Hitt, B., O'Connor, T., Logan, S., Maus, E., Citron, M., Berry, R., Binder, L., and Vassar, R. (2007) J. Neurosci. 27, 3639-3649
24. Walmsley, A. R., Zeng, F., and Hooper, N. M. (2001) EMBO J. 20, 703-712
25. Mucke, L., Masliah, E., Yu, G. Q., Mallory, M., Rockenstein, E. M., Tatsuno, G., Hu, K., Kholodenko, D., Johnson-Wood, K., and McConlogue, L. (2000) J. Neurosci. 20, 4050-4058
26. Piccardo, P., Manson, J. C., King, D., Ghetti, B., and Barron, R. M. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 4712-4717
27. Kawarabayashi, T., Younkin, L. H., Saido, T. C., Shoji, M., Ashe, K. H., and Younkin, S. G. (2001) J. Neurosci. 21, 372-381
28. Haugabook, S. J., Yager, D. M., Eckman, E. A., Golde, T. E., Younkin, S. G., and Eckman, C. B. (2001) J. Neurosci. Methods 108, 171-179
29. Bennett, B. D., Babu-Khan, S., Loeloff, R., Louis, J. C., Curran, E., Citron, M., and Vassar, R. (2000) J. Biol. Chem. 275, 20647-20651
30. Sun, X., He, G., and Song, W. (2006) FASEB J. 20, 1369-1376
31. Walsh, D. M., and Selkoe, D. J. (2007) J. Neurochem. 101, 1172-1184
32. Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Science 300, 486-489
33. Kayed, R., Head, E., Sarsoza, F., Saing, T., Cotman, C. W., Necula, M., Margol, L., Wu, J., Breydo, L., Thompson, J. L., Rasool, S., Gurlo, T., Butler, P., and Glabe, C. G. (2007) Mol. Neurodegener. 2, 18
34. Cole, S. L., and Vassar, R. (2007) Mol. Neurodegener. 2, 22
35. Andersen, O. M., Reiche, J., Schmidt, V., Gotthardt, M., Spoelgen, R., Behlke, J., von Arnim, C. A., Breiderhoff, T., Jansen, P., Wu, X., Bales, K. R., Cappai, R., Masters, C. L., Gliemann, J., Mufson, E. J., Hyman, B. T., Paul, S. M., Nykjaer, A., and Willnow, T. E. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 13461-13466
36. Spoelgen, R., von Arnim, C. A., Thomas, A. V., Peltan, I. D., Koker, M., Deng, A., Irizarry, M. C., Andersen, O. M., Willnow, T. E., and Hyman, B. T. (2006) J. Neurosci. 26, 418-428
37. Gimbel, D. A., Nygaard, H. B., Coffey, E. E., Gunther, E. C., Laurén, J., Gimbel, Z. A., and Strittmatter, S. M. (2010) J. Neurosci. 30, 6367-6374
38. Calella, A. M., Farinelli, M., Nuvolone, M., Mirante, O., Moos, R., Falsig, J., Mansuy, I. M., and Aguzzi, A. (2010) EMBO Mol. Med. 2, 306-314
39. Schwarze-Eicker, K., Keyvani, K., Görtz, N., Westaway, D., Sachser, N., and Paulus, W. (2005) Neurobiol. Aging 26, 1177-1182
40. Yamakawa, H., Yagishita, S., Futai, E., and Ishiura, S. (2010) J. Biol. Chem. 285, 1634-1642