-
1
-
-
0041733065
-
Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase
-
Achan V, Broadhead M, Malaki M, Whitley G, Leiper J, MacAllister R, Vallance P. Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase. Arterioscler Thromb Vasc Biol 23: 1455-1459, 2003.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1455-1459
-
-
Achan, V.1
Broadhead, M.2
Malaki, M.3
Whitley, G.4
Leiper, J.5
Macallister, R.6
Vallance, P.7
-
2
-
-
0031002483
-
Oral-arginine improves endothelium-dependent dilatation and reduces monocyte adhesion to endothelial cells in young men with coronary artery disease
-
Adams MR, McCredie R, Jessup W, Robinson J, Sullivan D, Celermajer DS. Oral-arginine improves endothelium-dependent dilatation and reduces monocyte adhesion to endothelial cells in young men with coronary artery disease. Atherosclerosis 129: 261-269, 1997.
-
(1997)
Atherosclerosis
, vol.129
, pp. 261-269
-
-
Adams, M.R.1
McCredie, R.2
Jessup, W.3
Robinson, J.4
Sullivan, D.5
Celermajer, D.S.6
-
3
-
-
0025605627
-
Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung
-
Adkins W, Taylor A. Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung. J Appl Physiol 69: 2012, 1990.
-
(1990)
J Appl Physiol
, vol.69
, pp. 2012
-
-
Adkins, W.1
Taylor, A.2
-
4
-
-
0345276632
-
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
-
Aicher A, Heeschen C, Mildner-Rihm C, Urbich C, Ihling C, Technau-Ihling K, Zeiher AM, Dimmeler S. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 9: 1370-1376, 2003.
-
(2003)
Nat Med
, vol.9
, pp. 1370-1376
-
-
Aicher, A.1
Heeschen, C.2
Mildner-Rihm, C.3
Urbich, C.4
Ihling, C.5
Technau-Ihling, K.6
Zeiher, A.M.7
Dimmeler, S.8
-
5
-
-
0031023733
-
L-Arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice
-
Aji W, Ravalli S, Szabolcs M, Jiang Xc Sciacca RR, Michler RE, Cannon PJ. L-Arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice. Circulation 95: 430-437, 1997.
-
(1997)
Circulation
, vol.95
, pp. 430-437
-
-
Aji, W.1
Ravalli, S.2
Szabolcs, M.3
Jiang Xc Sciacca, R.R.4
Michler, R.E.5
Cannon, P.J.6
-
6
-
-
1542283780
-
Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease
-
Alp NJ, Channon KM. Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease. Arterioscler Thromb Vasc Biol 24: 413-420, 2004.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 413-420
-
-
Alp, N.J.1
Channon, K.M.2
-
7
-
-
1542344000
-
Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in apoE-knockout mice
-
Alp NJ, McAteer MA, Khoo J, Choudhury RP, Channon KM. Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in apoE-knockout mice. Arterioscler Thromb Vasc Biol 24: 445-450, 2004.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 445-450
-
-
Alp, N.J.1
McAteer, M.A.2
Khoo, J.3
Choudhury, R.P.4
Channon, K.M.5
-
8
-
-
0024562467
-
Flow-mediated and reflex changes in large peripheral artery tone in humans
-
Anderson EA, Mark AL. Flow-mediated and reflex changes in large peripheral artery tone in humans. Circulation 79: 93-100, 1989.
-
(1989)
Circulation
, vol.79
, pp. 93-100
-
-
Anderson, E.A.1
Mark, A.L.2
-
9
-
-
0028939363
-
The effect of cholesterol-lowering and antioxidant therapy on endothelium- dependent coronary vasomotion
-
Anderson TJ, Meredith IT, Yeung AC, Frei B, Selwyn AP, Ganz P. The effect of cholesterol-lowering and antioxidant therapy on endothelium- dependent coronary vasomotion. N Engl J Med 332: 488-493, 1995.
-
(1995)
N Engl J Med
, vol.332
, pp. 488-493
-
-
Anderson, T.J.1
Meredith, I.T.2
Yeung, A.C.3
Frei, B.4
Selwyn, A.P.5
Ganz, P.6
-
10
-
-
65949123566
-
Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide productionand endothelial nitric oxide synthase uncoupling: Implications for endothelial function in human atherosclerosis
-
Antoniades C, Shirodaria C, Leeson P, Antonopoulos A, Warrick N, Van-Assche T, Cunnington C, Tousoulis D, Pillai R, Ratnatunga C, Stefanadis C, Channon KM. Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide productionand endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis. Eur Heart J 30: 1142-1150, 2009.
-
(2009)
Eur Heart J
, vol.30
, pp. 1142-1150
-
-
Antoniades, C.1
Shirodaria, C.2
Leeson, P.3
Antonopoulos, A.4
Warrick, N.5
Van-Assche, T.6
Cunnington, C.7
Tousoulis, D.8
Pillai, R.9
Ratnatunga, C.10
Stefanadis, C.11
Channon, K.M.12
-
11
-
-
33748645122
-
5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: Effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling
-
Antoniades C, Shirodaria C, Warrick N, Cai S, de Bono J, Lee J, Leeson P, Neubauer S, Ratnatunga C, Pillai R, Refsum H, Channon KM. 5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling. Circulation 114: 1193-1201, 2006.
-
(2006)
Circulation
, vol.114
, pp. 1193-1201
-
-
Antoniades, C.1
Shirodaria, C.2
Warrick, N.3
Cai, S.4
de Bono, J.5
Lee, J.6
Leeson, P.7
Neubauer, S.8
Ratnatunga, C.9
Pillai, R.10
Refsum, H.11
Channon, K.M.12
-
12
-
-
3242678848
-
Arginase pathway in human endothelial cells in pathophysiological conditions
-
Bachetti T, Comini L, Francolini G, Bastianon D, Valetti B, Cadei M, Grigolato P, Suzuki H, Finazzi D, Albertini A, Curello S, Ferrari R. Arginase pathway in human endothelial cells in pathophysiological conditions. J Mol Cell Cardiol 37: 515-523, 2004.
-
(2004)
J Mol Cell Cardiol
, vol.37
, pp. 515-523
-
-
Bachetti, T.1
Comini, L.2
Francolini, G.3
Bastianon, D.4
Valetti, B.5
Cadei, M.6
Grigolato, P.7
Suzuki, H.8
Finazzi, D.9
Albertini, A.10
Curello, S.11
Ferrari, R.12
-
13
-
-
27644537902
-
Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: Insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS Overexpression
-
Bendall JK, Alp NJ, Warrick N, Cai S, Adlam D, Rockett K, Yokoyama M, Kawashima S, Channon KM. Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS Overexpression. Circ Res 97: 864-871, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 864-871
-
-
Bendall, J.K.1
Alp, N.J.2
Warrick, N.3
Cai, S.4
Adlam, D.5
Rockett, K.6
Yokoyama, M.7
Kawashima, S.8
Channon, K.M.9
-
14
-
-
3543042462
-
Three different oxygeninduced radical species in endothelial nitric-oxide synthase oxygenase domain under regulation by L-arginine and tetrahydrobiopterin
-
Berka V, Wu G, Yeh HC, Palmer G, Tsai Al. Three different oxygeninduced radical species in endothelial nitric-oxide synthase oxygenase domain under regulation by L-arginine and tetrahydrobiopterin. J Biol Chem 279: 32243-32251, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 32243-32251
-
-
Berka, V.1
Wu, G.2
Yeh, H.C.3
Palmer, G.4
Tsai, A.5
-
15
-
-
0042860120
-
Microvascular oxygenation, oxidative stress, NO suppression, and superoxide dismutase during postischemic reperfusion
-
Bertuglia S, Giusti A. Microvascular oxygenation, oxidative stress, NO suppression, and superoxide dismutase during postischemic reperfusion. Am J Physiol Heart Circ Physiol 285: H1064-H1071, 2003.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
-
-
Bertuglia, S.1
Giusti, A.2
-
16
-
-
0141607693
-
Oral L-arginine improves endothelial function in healthy individuals older than 70 years
-
Bode-Boger SM, Muke J, Surdacki A, Brabant G, Boger RH, Frolich JC. Oral L-arginine improves endothelial function in healthy individuals older than 70 years. Vasc Med 8: 77-81, 2003.
-
(2003)
Vasc Med
, vol.8
, pp. 77-81
-
-
Bode-Boger, S.M.1
Muke, J.2
Surdacki, A.3
Brabant, G.4
Boger, R.H.5
Frolich, J.C.6
-
17
-
-
34249706763
-
The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio
-
Bode-Boger SM, Scalera F, Ignarro LJ. The L-arginine paradox: importance of the L-arginine/asymmetrical dimethylarginine ratio. Pharmacol Therapeut 114: 295-306, 2007.
-
(2007)
Pharmacol Therapeut
, vol.114
, pp. 295-306
-
-
Bode-Boger, S.M.1
Scalera, F.2
Ignarro, L.J.3
-
18
-
-
0342378190
-
Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: Comparison with lovastatin
-
Boger RH, Bode-Boger SM, Brandes RP, Phivthong-ngam L, Bohme M, Nafe R, Mugge A, Frolich JC. Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. Circulation 96: 1282-1290, 1997.
-
(1997)
Circulation
, vol.96
, pp. 1282-1290
-
-
Boger, R.H.1
Bode-Boger, S.M.2
Brandes, R.P.3
Phivthong-Ngam, L.4
Bohme, M.5
Nafe, R.6
Mugge, A.7
Frolich, J.C.8
-
19
-
-
33645796222
-
Homocysteine lowering and cardiovascular events after acute myocardial infarction
-
Bonaa KH, Njolstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T, Wang H, Nordrehaug JE, Arnesen E, Rasmussen K. Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med 354: 1578-1588, 2006.
-
(2006)
N Engl J Med
, vol.354
, pp. 1578-1588
-
-
Bonaa, K.H.1
Njolstad, I.2
Ueland, P.M.3
Schirmer, H.4
Tverdal, A.5
Steigen, T.6
Wang, H.7
Nordrehaug, J.E.8
Arnesen, E.9
Rasmussen, K.10
-
20
-
-
0036791644
-
Human macrophage-induced vascular smooth muscle cell apoptosis requires NO enhancement of Fas/Fas-L interactions
-
Boyle JJ, Weissberg PL, Bennett MR. Human macrophage-induced vascular smooth muscle cell apoptosis requires NO enhancement of Fas/Fas-L interactions. Arterioscler Thromb Vasc Biol 22: 1624-1630, 2002.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1624-1630
-
-
Boyle, J.J.1
Weissberg, P.L.2
Bennett, M.R.3
-
21
-
-
77951879565
-
Atrial expression of endothelial nitric oxide synthase in patients with and without atrial fibrillation
-
Bukowska A, Rocken C, Erxleben M, Rohl FW, Hammwohner M, Huth C, Ebert MPA, Lendeckel U, Goette A. Atrial expression of endothelial nitric oxide synthase in patients with and without atrial fibrillation. Cardiovasc Pathol 19: e51-e60, 2010.
-
(2010)
Cardiovasc Pathol
, vol.19
-
-
Bukowska, A.1
Rocken, C.2
Erxleben, M.3
Rohl, F.W.4
Hammwohner, M.5
Huth, C.6
Ebert, M.P.A.7
Lendeckel, U.8
Goette, A.9
-
22
-
-
0036251095
-
Lisdat F
-
Büttemeyer R, Philipp AW, Mall JW, Ge B, Scheller FW, Lisdat F. In vivo measurement of oxygen derived free radicals during reperfusion injury. Microsurgery 22: 108-113, 2002.
-
(2002)
Vivo Measurement of Oxygen Derived Free Radicals During Reperfusion Injury. Microsurgery
, vol.22
, pp. 108-113
-
-
Büttemeyer, R.1
Philipp, A.W.2
Mall, J.W.3
Ge, B.4
Scheller, F.W.5
-
23
-
-
0037180407
-
Downregulation of endocardial nitric oxide synthase expression and nitric oxide production in atrial fibrillation
-
Cai H, Li Z, Goette A, Mera F, Honeycutt C, Feterik K, Wilcox JN, Dudley SC, Harrison DG, Langberg JJ. Downregulation of endocardial nitric oxide synthase expression and nitric oxide production in atrial fibrillation. Circulation 106: 2854-2858, 2002.
-
(2002)
Circulation
, vol.106
, pp. 2854-2858
-
-
Cai, H.1
Li, Z.2
Goette, A.3
Mera, F.4
Honeycutt, C.5
Feterik, K.6
Wilcox, J.N.7
Dudley, S.C.8
Harrison, D.G.9
Langberg, J.J.10
-
24
-
-
21144435142
-
Endothelial dihydrofolate reductase: Critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase
-
Chalupsky K, Cai H. Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase. Proc Natl Acad Sci USA 102: 9056-9061, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9056-9061
-
-
Chalupsky, K.1
Cai, H.2
-
25
-
-
13444262357
-
Tetrahydrobiopterin: Regulator of endothelial nitric oxide synthase in vascular disease
-
Channon K. Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc Med 14: 323-327, 2004.
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 323-327
-
-
Channon, K.1
-
26
-
-
0035942232
-
Inhibits vascular endothelial growth factorinduced endothelial cell migration by an inhibitory effect on the Akt/ endothelial nitric oxide synthase pathway
-
Chavakis E, Dernbach E, Hermann C, Mondorf UF, Zeiher AM, Dimmeler S. Oxidized LDL inhibits vascular endothelial growth factorinduced endothelial cell migration by an inhibitory effect on the Akt/ endothelial nitric oxide synthase pathway. Circulation 103: 2102-2107, 2001.
-
(2001)
Circulation
, vol.103
, pp. 2102-2107
-
-
Chavakis, E.1
Dernbach, E.2
Hermann, C.3
Mondorf, U.F.4
Zeiher, A.M.5
Dimmeler, S.6
Oxidized, L.D.L.7
-
27
-
-
33846335174
-
Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion
-
Chen Q, Camara AKS, Stowe DF, Hoppel CL, Lesnefsky EJ. Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion. Am J Physiol Cell Physiol 292: C137-C147, 2007.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Chen, Q.1
Camara, A.K.S.2
Stowe, D.F.3
Hoppel, C.L.4
Lesnefsky, E.J.5
-
28
-
-
0034723761
-
Blood levels of homocysteine and increased risks of cardiovascular disease: Causal or casual?
-
Christen WG, Ajani UA, Glynn RJ, Hennekens CH. Blood levels of homocysteine and increased risks of cardiovascular disease: causal or casual? Arch Intern Med 160: 422-434, 2000.
-
(2000)
Arch Intern Med
, vol.160
, pp. 422-434
-
-
Christen, W.G.1
Ajani, U.A.2
Glynn, R.J.3
Hennekens, C.H.4
-
29
-
-
15844389652
-
Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults
-
Clarkson P, Adams MR, Powe AJ, Donald AE, McCredie R, Robinson J, McCarthy SN, Keech A, Celermajer DS, Deanfield JE. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults. J Clin Invest 97: 1989-1994, 1996.
-
(1996)
J Clin Invest
, vol.97
, pp. 1989-1994
-
-
Clarkson, P.1
Adams, M.R.2
Powe, A.J.3
Donald, A.E.4
McCredie, R.5
Robinson, J.6
McCarthy, S.N.7
Keech, A.8
Celermajer, D.S.9
Deanfield, J.E.10
-
30
-
-
0030837996
-
High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
-
Cosentino F, Hishikawa K, Katusic ZS, Luscher TF. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96: 25-28, 1997.
-
(1997)
Circulation
, vol.96
, pp. 25-28
-
-
Cosentino, F.1
Hishikawa, K.2
Katusic, Z.S.3
Luscher, T.F.4
-
31
-
-
41149105370
-
Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia
-
Cosentino F, Hurlimann D, Delli Gatti C, Chenevard R, Blau N, Alp NJ, Channon KM, Eto M, Lerch P, Enseleit F, Ruschitzka F, Volpe M, Lüscher TF, Noll G. Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia. Heart 94: 487-492, 2008.
-
(2008)
Heart
, vol.94
, pp. 487-492
-
-
Cosentino, F.1
Hurlimann, D.2
Delli, G.C.3
Chenevard, R.4
Blau, N.5
Alp, N.J.6
Channon, K.M.7
Eto, M.8
Lerch, P.9
Enseleit, F.10
Ruschitzka, F.11
Volpe, M.12
Lüscher, T.F.13
Noll, G.14
-
32
-
-
79955613244
-
Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
-
Crabtree MJ, Hale AB, Channon KM. Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency. Free Radic Biol Med 50: 1639-1646, 2011.
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 1639-1646
-
-
Crabtree, M.J.1
Hale, A.B.2
Channon, K.M.3
-
33
-
-
41849144894
-
Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS
-
Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS. Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS. Am J Physiol Heart Circ Physiol 294: H1530-H1540, 2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Crabtree, M.J.1
Smith, C.L.2
Lam, G.3
Goligorsky, M.S.4
Gross, S.S.5
-
34
-
-
59449086328
-
Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterineNOS stoichiometry and biopterin redox status
-
Crabtree MJ, Tatham AL, Al-Wakeel Y, Warrick N, Hale AB, Cai S, Channon KM, Alp NJ. Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterineNOS stoichiometry and biopterin redox status. J Biol Chem 284: 1136-1144, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 1136-1144
-
-
Crabtree, M.J.1
Tatham, A.L.2
Al-Wakeel, Y.3
Warrick, N.4
Hale, A.B.5
Cai, S.6
Channon, K.M.7
Alp, N.J.8
-
35
-
-
79960778588
-
Is NOS uncoupling the missing link between atrial fibrillation and chronic non-ischaemic cardiomyopathy?
-
Crijns HJ, Schotten U, Moens AL. Is NOS uncoupling the missing link between atrial fibrillation and chronic non-ischaemic cardiomyopathy? Cardiovasc Res 91: 556, 2011.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 556
-
-
Crijns, H.J.1
Schotten, U.2
Moens, A.L.3
-
36
-
-
78650794625
-
Transplantation of endothelial progenitor cells overexpressing endothelial nitric oxide synthase enhances inhibition of neointimal hyperplasia and restores endothelium- dependent vasodilatation
-
Cui B, Huang L, Fang Y, Guo R, Yin Y, Zhao X. Transplantation of endothelial progenitor cells overexpressing endothelial nitric oxide synthase enhances inhibition of neointimal hyperplasia and restores endothelium- dependent vasodilatation. Microvasc Res 81: 143-150, 2011.
-
(2011)
Microvasc Res
, vol.81
, pp. 143-150
-
-
Cui, B.1
Huang, L.2
Fang, Y.3
Guo, R.4
Yin, Y.5
Zhao, X.6
-
37
-
-
34247853270
-
Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin
-
d'Uscio LV, Smith LA, Santhanam AV, Richardson D, Nath KA, Katusic ZS. Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin. Hypertension 49: 1142-1148, 2007.
-
(2007)
Hypertension
, vol.49
, pp. 1142-1148
-
-
D'Uscio, L.V.1
Smith, L.A.2
Santhanam, A.V.3
Richardson, D.4
Nath, K.A.5
Katusic, Z.S.6
-
38
-
-
2942733214
-
Role of endothelial dysfunction in atherosclerosis
-
III-27-32
-
Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 109: III-27-32, 2004.
-
(2004)
Circulation
, vol.109
-
-
Davignon, J.1
Ganz, P.2
-
39
-
-
0037743396
-
Tetrahydrobiopterin attenuates homocysteine induced endothelial dysfunction
-
Dhillon B, Badiwala MV, Maitland A, Rao V, Li SH, Verma S. Tetrahydrobiopterin attenuates homocysteine induced endothelial dysfunction. Mol Cell Biochem 247: 223-227, 2003.
-
(2003)
Mol Cell Biochem
, vol.247
, pp. 223-227
-
-
Dhillon, B.1
Badiwala, M.V.2
Maitland, A.3
Rao, V.4
Li, S.H.5
Verma, S.6
-
40
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Aktdependent phosphorylation
-
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Aktdependent phosphorylation. Nature 399: 601-605, 1999.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
41
-
-
7944223539
-
Vascular repair by circulating endothelial progenitor cells: The missing link in atherosclerosis?
-
Dimmeler S, Zeiher AM. Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis? J Mol Med 82: 671-677, 2004.
-
(2004)
J Mol Med
, vol.82
, pp. 671-677
-
-
Dimmeler, S.1
Zeiher, A.M.2
-
42
-
-
0035721992
-
Folate improves endothelial function in coronary artery disease: An effect mediated by reduction of intracellular superoxide?
-
Doshi SN, McDowell IFW, Moat SJ, Lang D, Newcombe RG, Kredan MB, Lewis MJ, Goodfellow J. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arterioscler Thromb Vasc Biol 21: 1196-1202, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1196-1202
-
-
Doshi, S.N.1
McDowell, I.F.W.2
Moat, S.J.3
Lang, D.4
Newcombe, R.G.5
Kredan, M.B.6
Lewis, M.J.7
Goodfellow, J.8
-
43
-
-
35448929005
-
Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4
-
Dumitrescu C, Biondi R, Xia Y, Cardounel AJ, Druhan LJ, Ambrosio G, Zweier JL. Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4. Proc Natl Acad Sciences USA 104: 15081-15086, 2007.
-
(2007)
Proc Natl Acad Sciences USA
, vol.104
, pp. 15081-15086
-
-
Dumitrescu, C.1
Biondi, R.2
Xia, Y.3
Cardounel, A.J.4
Druhan, L.J.5
Ambrosio, G.6
Zweier, J.L.7
-
44
-
-
35448929005
-
Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4
-
Dumitrescu C, Biondi R, Xia Y, Cardounel AJ, Druhan LJ, Ambrosio G, Zweier JL. Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4. Proc Natl Acad Sciences USA 104: 15081, 2007.
-
(2007)
Proc Natl Acad Sciences USA
, vol.104
, pp. 15081
-
-
Dumitrescu, C.1
Biondi, R.2
Xia, Y.3
Cardounel, A.J.4
Druhan, L.J.5
Ambrosio, G.6
Zweier, J.L.7
-
45
-
-
0035902547
-
Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase
-
Duplain H, Burcelin Rm Sartori C, Cook Sp Egli M, Lepori M, Vollenweider P, Pedrazzini T, Nicod P, Thorens B, Scherrer U. Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase. Circulation 104: 342-345, 2001.
-
(2001)
Circulation
, vol.104
, pp. 342-345
-
-
Duplain, H.1
Burcelin Rm Sartori, C.2
Cook Sp Egli, M.3
Lepori, M.4
Vollenweider, P.5
Pedrazzini, T.6
Nicod, P.7
Thorens, B.8
Scherrer, U.9
-
46
-
-
0037592128
-
Hyperhomocysteinemia due to folate deficiency is thrombogenic in rats
-
Ebbesen LS, Christiansen K, Ingerslev J. Hyperhomocysteinemia due to folate deficiency is thrombogenic in rats. J Nutr 133: 2250-2255, 2003.
-
(2003)
J Nutr
, vol.133
, pp. 2250-2255
-
-
Ebbesen, L.S.1
Christiansen, K.2
Ingerslev, J.3
-
47
-
-
77956246887
-
Cigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction: Role of VEGFR2
-
Edirisinghe I, Rahman I. Cigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction: role of VEGFR2. Ann NY Acad Sci 1203: 66-72, 2010.
-
(2010)
Ann NY Acad Sci
, vol.1203
, pp. 66-72
-
-
Edirisinghe, I.1
Rahman, I.2
-
48
-
-
46749139440
-
VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction
-
Edirisinghe I, Yang SR, Yao H, Rajendrasozhan S, Caito S, Adenuga D, Wong C, Rahman A, Phipps RP, Jin ZG, Rahman I. VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction. FASEB J 22: 2297-2310, 2008.
-
(2008)
FASEB J
, vol.22
, pp. 2297-2310
-
-
Edirisinghe, I.1
Yang, S.R.2
Yao, H.3
Rajendrasozhan, S.4
Caito, S.5
Adenuga, D.6
Wong, C.7
Rahman, A.8
Phipps, R.P.9
Jin, Z.G.10
Rahman, I.11
-
49
-
-
77954689257
-
Changes in caveolin-1 expression and vasoreac-tivity in the aorta and corpus cavernosum of fructose and streptozotocininduced diabetic rats
-
Elçioglu KH, Kabasakal L, Çetinel S, Conturk G, Sezen SF, Ayanoglu-Dülger G. Changes in caveolin-1 expression and vasoreac-tivity in the aorta and corpus cavernosum of fructose and streptozotocininduced diabetic rats. Eur J Pharmacol 642: 113-120, 2010.
-
(2010)
Eur J Pharmacol
, vol.642
, pp. 113-120
-
-
Elçioglu, K.H.1
Kabasakal, L.2
Çetinel, S.3
Conturk, G.4
Sezen, S.F.5
Ayanoglu-Dülger, G.6
-
50
-
-
0035830412
-
Reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance
-
Feron O, Dessy C, Desager JP, Balligand JL. Hydroxy-methylglutarylcoenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance. Circulation 103: 113-118, 2001.
-
(2001)
Circulation
, vol.103
, pp. 113-118
-
-
Feron, O.1
Dessy, C.2
Desager, J.P.3
Balligand, J.L.4
Hydroxy-Methylglutarylcoenzyme, A.5
-
51
-
-
84857379924
-
Reactive oxygen species and cell signaling in lung ischemia
-
Fisher AB. Reactive oxygen species and cell signaling in lung ischemia. Cell Signaling Vasc Inflammation 125-135, 2005.
-
(2005)
Cell Signaling Vasc Inflammation
, pp. 125-135
-
-
Fisher, A.B.1
-
52
-
-
79960392882
-
Critical role of the nitric oxide/reactive oxygen species balance in endothelial progenitor dysfunction
-
Fleissner F, Thum T. Critical role of the nitric oxide/reactive oxygen species balance in endothelial progenitor dysfunction. Antioxidants Redox Signaling 15: 933-948, 2011.
-
(2011)
Antioxidants Redox Signaling
, vol.15
, pp. 933-948
-
-
Fleissner, F.1
Thum, T.2
-
53
-
-
0023750135
-
Response of human coronary arteries to aggregating platelets: Importance of endotheliumderived relaxing factor and prostanoids
-
Forstermann U, Mugge A, Bode SM, Frolich JC. Response of human coronary arteries to aggregating platelets: importance of endotheliumderived relaxing factor and prostanoids. Circ Res 63: 306-312, 1988.
-
(1988)
Circ Res
, vol.63
, pp. 306-312
-
-
Forstermann, U.1
Mugge, A.2
Bode, S.M.3
Frolich, J.C.4
-
54
-
-
53749096012
-
Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction
-
Fraccarollo D, Widder JD, Galuppo P, Thum T, Tsikas D, Hoffmann M, Ruetten H, Ertl G, Bauersachs J. Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction. Circulation 118: 818-827, 2008.
-
(2008)
Circulation
, vol.118
, pp. 818-827
-
-
Fraccarollo, D.1
Widder, J.D.2
Galuppo, P.3
Thum, T.4
Tsikas, D.5
Hoffmann, M.6
Ruetten, H.7
Ertl, G.8
Bauersachs, J.9
-
55
-
-
70349652240
-
The eNOS enhancer AVE 9488: A novel cardioprotectant against ischemia reperfusion injury
-
Frantz S, Adamek A, Fraccarollo D, Tillmanns J, Widder J, Dienesch C, Schäfer A, Podolskaya A, Held M, Ruetten H, Ertl G, Bauersachs J. The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury. Basic Res Cardiol 104: 773-779, 2009.
-
(2009)
Basic Res Cardiol
, vol.104
, pp. 773-779
-
-
Frantz, S.1
Adamek, A.2
Fraccarollo, D.3
Tillmanns, J.4
Widder, J.5
Dienesch, C.6
Schäfer, A.7
Podolskaya, A.8
Held, M.9
Ruetten, H.10
Ertl, G.11
Bauersachs, J.12
-
56
-
-
0033542414
-
Regulation of endothelium- derived nitric oxide production by the protein kinase Akt
-
Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium- derived nitric oxide production by the protein kinase Akt. Nature 399: 597-601, 1999.
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
Fontana, J.4
Fujio, Y.5
Walsh, K.6
Franke, T.F.7
Papapetropoulos, A.8
Sessa, W.C.9
-
57
-
-
35348966158
-
Oxygen metabolism by endothelial nitric-oxide synthase
-
Gao YT, Roman LJ, Martasek P, Panda SP, Ishimura Y, Masters BSS. Oxygen metabolism by endothelial nitric-oxide synthase. J Biol Chem 282: 28557-28565, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 28557-28565
-
-
Gao, Y.T.1
Roman, L.J.2
Martasek, P.3
Panda, S.P.4
Ishimura, Y.5
Masters, B.S.S.6
-
58
-
-
84857415020
-
The impact of rapid atrial pacing on ADMA and endothelial NOS
-
Oct 4. [Epub ahead of print] PMID: 20926145
-
Goette A, Hammwöhner M, Bukowska A, Scalera F, Martens- Lobenhoffer J, Dobrev D, Ravens U, Weinert S, Medunjanin S, Lendeckel U. The impact of rapid atrial pacing on ADMA and endothelial NOS. Int J Cardiol 2010 Oct 4. [Epub ahead of print] PMID: 20926145.
-
(2010)
Int J Cardiol
-
-
Goette, A.1
Hammwöhner, M.2
Bukowska, A.3
Scalera, F.4
Martens-lobenhoffer, J.5
Dobrev, D.6
Ravens, U.7
Weinert, S.8
Medunjanin, S.9
Lendeckel, U.10
-
59
-
-
79955656767
-
Hyperglycemia induces apoptosis of pancreatic islet endothelial cells via reactive nitrogen species-mediated Jun N-terminal kinase activation
-
Gong L, Liu Fq Wang J, Wang Xp Hou Xg Sun Y, Qin Wd Wei Sj Zhang Y, Chen L, Zhang MX. Hyperglycemia induces apoptosis of pancreatic islet endothelial cells via reactive nitrogen species-mediated Jun N-terminal kinase activation. Biochim Biophys Acta 1813: 1211-1219, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1211-1219
-
-
Gong, L.1
Liu Fq Wang, J.2
Wang Xp Hou Xg Sun, Y.3
Qin Wd Wei Sj Zhang, Y.4
Chen, L.5
Zhang, M.X.6
-
60
-
-
34249744707
-
Transgenic expression of human C-reactive protein suppresses endothelial nitric oxide synthase expression and bioactivity after vascular injury
-
Grad E, Golomb M, Mor-Yosef I, Koroukhov N, Lotan C, Edelman ER, Danenberg HD. Transgenic expression of human C-reactive protein suppresses endothelial nitric oxide synthase expression and bioactivity after vascular injury. Am J Physiol Heart Circ Physiol 293: H489-H495, 2007.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Grad, E.1
Golomb, M.2
Mor-Yosef, I.3
Koroukhov, N.4
Lotan, C.5
Edelman, E.R.6
Danenberg, H.D.7
-
61
-
-
0037173099
-
S-nitroso human serum albumin treatment reduces ischemia/reperfusion injury in skeletal muscle via nitric oxide release
-
Hallstrom S, Gasser H, Neumayer C, Fugl A, Nanobashvili J, Jakubowski A, Huk I, Schlag G, Malinski T. S-nitroso human serum albumin treatment reduces ischemia/reperfusion injury in skeletal muscle via nitric oxide release. Circulation 105: 3032-3038, 2002.
-
(2002)
Circulation
, vol.105
, pp. 3032-3038
-
-
Hallstrom, S.1
Gasser, H.2
Neumayer, C.3
Fugl, A.4
Nanobashvili, J.5
Jakubowski, A.6
Huk, I.7
Schlag, G.8
Malinski, T.9
-
62
-
-
79958833427
-
Nitric oxide: A key factor behind the dysfunctionality of endothelial progenitor cells in diabetes mellitus type-2
-
Hamed S, Brenner B, Roguin A. Nitric oxide: a key factor behind the dysfunctionality of endothelial progenitor cells in diabetes mellitus type-2. Cardiovasc Res 91: 9-15, 2010.
-
(2010)
Cardiovasc Res
, vol.91
, pp. 9-15
-
-
Hamed, S.1
Brenner, B.2
Roguin, A.3
-
63
-
-
54549094846
-
Nitric oxide overproduction derived from inducible nitric oxide synthase increases cardiomyocyte apoptosis in human atrial fibrillation
-
Han W, Fu S, Wei N, Xie B, Li W, Yang S, Li Y, Liang Z, Huo H. Nitric oxide overproduction derived from inducible nitric oxide synthase increases cardiomyocyte apoptosis in human atrial fibrillation. Int J Cardiol 130: 165-173, 2008.
-
(2008)
Int J Cardiol
, vol.130
, pp. 165-173
-
-
Han, W.1
Fu, S.2
Wei, N.3
Xie, B.4
Li, W.5
Yang, S.6
Li, Y.7
Liang, Z.8
Huo, H.9
-
64
-
-
34247877763
-
Oxidative stress and hypertension
-
Harrison DG, Gongora MC, Guzik TJ, Widder J. Oxidative stress and hypertension. J A Soc Hypertension 1: 30-44, 2007.
-
(2007)
J a Soc Hypertension
, vol.1
, pp. 30-44
-
-
Harrison, D.G.1
Gongora, M.C.2
Guzik, T.J.3
Widder, J.4
-
65
-
-
34247220499
-
Oral administration of tetrahydrobiopterin slows the progression of atherosclerosis in apolipoprotein E-knockout mice
-
Hattori Y, Hattori S, Wang X, Satoh H, Nakanishi N, Kasai K. Oral administration of tetrahydrobiopterin slows the progression of atherosclerosis in apolipoprotein E-knockout mice. Arterioscler Thromb Vasc Biol 27: 865-870, 2007.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 865-870
-
-
Hattori, Y.1
Hattori, S.2
Wang, X.3
Satoh, H.4
Nakanishi, N.5
Kasai, K.6
-
66
-
-
0345532411
-
Cyclohydrolase I. HMG-CoA reductase inhibitor increases GTP HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells
-
Hattori Y, Nakanishi N, Akimoto K, Yoshida M, Kasai K. HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells. Arterioscler Thromb Vasc Biol 23: 176-182, 2003.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 176-182
-
-
Hattori, Y.1
Nakanishi, N.2
Akimoto, K.3
Yoshida, M.4
Kasai, K.5
-
67
-
-
0032416119
-
Time course of endothelial-neutrophil interaction in splanchnic artery ischemia-reperfusion
-
Hayward R, Lefer AM. Time course of endothelial-neutrophil interaction in splanchnic artery ischemia-reperfusion. Am J Physiol Heart Circ Physiol 275: H2080-H2086, 1998.
-
(1998)
Am J Physiol Heart Circ Physiol
, vol.275
-
-
Hayward, R.1
Lefer, A.M.2
-
68
-
-
78649671320
-
Homocysteine impairs coronary artery endothelial function by inhibiting tetrahydrobiopterin in patients with hyperhomocysteinemia
-
He L, Zeng H, Li F, Feng J, Liu S, Liu J, Yu J, Mao J, Hong T, Chen AF, Wang X, Wang G. Homocysteine impairs coronary artery endothelial function by inhibiting tetrahydrobiopterin in patients with hyperhomocysteinemia. Am J Physiol Endocrinol Metab 299: E1061-E1065, 2010.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
-
-
He, L.1
Zeng, H.2
Li, F.3
Feng, J.4
Liu, S.5
Liu, J.6
Yu, J.7
Mao, J.8
Hong, T.9
Chen, A.F.10
Wang, X.11
Wang, G.12
-
69
-
-
0034602878
-
Tetrahydrobiopterin improves endotheliumdependent vasodilation in chronic smokers: Evidence for a dysfunctional nitric oxide synthase
-
Heitzer T, Brockhoff C, Mayer B, Warnholtz A, Mollnau H, Henne S, Meinertz T, Munzel T. Tetrahydrobiopterin improves endotheliumdependent vasodilation in chronic smokers: evidence for a dysfunctional nitric oxide synthase. Circ Res 86: e36-e41, 2000.
-
(2000)
Circ Res
, vol.86
-
-
Heitzer, T.1
Brockhoff, C.2
Mayer, B.3
Warnholtz, A.4
Mollnau, H.5
Henne, S.6
Meinertz, T.7
Munzel, T.8
-
70
-
-
0033752910
-
Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus
-
Heitzer T, Krohn K, Albers S, Meinertz T. Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia 43: 1435-1438, 2000.
-
(2000)
Diabetologia
, vol.43
, pp. 1435-1438
-
-
Heitzer, T.1
Krohn, K.2
Albers, S.3
Meinertz, T.4
-
71
-
-
0036100972
-
Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals[ast]
-
Higashi Y, Sasaki S, Nakagawa K, Fukuda Y, Matsuura H, Oshima T, Chayama K. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals[ast]. Am J Hypertens 15: 326-332, 2002.
-
(2002)
Am J Hypertens
, vol.15
, pp. 326-332
-
-
Higashi, Y.1
Sasaki, S.2
Nakagawa, K.3
Fukuda, Y.4
Matsuura, H.5
Oshima, T.6
Chayama, K.7
-
72
-
-
33646402907
-
Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production
-
Higashi Y, Sasaki S, Nakagawa K, Kimura M, Noma K, Hara K, Jitsuiki D, Goto C, Oshima T, Chayama K, Yoshizumi M. Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production. Atherosclerosis 186: 390-395, 2006.
-
(2006)
Atherosclerosis
, vol.186
, pp. 390-395
-
-
Higashi, Y.1
Sasaki, S.2
Nakagawa, K.3
Kimura, M.4
Noma, K.5
Hara, K.6
Jitsuiki, D.7
Goto, C.8
Oshima, T.9
Chayama, K.10
Yoshizumi, M.11
-
73
-
-
0035793616
-
Mechanisms underlying endothelial dysfunction in diabetes mellitus
-
Hink U, Li H, Mollnau H, Oelze M, Matheis E, Hartmann M, Skatchkov M, Thaiss F, Stahl RAK, Warnholtz A, Meinertz T, Griendling K, Harrison DG, Forstermann U, Munzel T. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 88: e14-22, 2001.
-
(2001)
Circ Res
, vol.88
-
-
Hink, U.1
Li, H.2
Mollnau, H.3
Oelze, M.4
Matheis, E.5
Hartmann, M.6
Skatchkov, M.7
Thaiss, F.8
Stahl, R.A.K.9
Warnholtz, A.10
Meinertz, T.11
Griendling, K.12
Harrison, D.G.13
Forstermann, U.14
Munzel, T.15
-
74
-
-
0028798319
-
Inhibition of endothelial nitric oxide synthase activity by protein kinase C
-
Hirata Ki Kuroda R, Sakoda T, Katayama M, Inoue N, Suematsu M, Kawashima S, Yokoyama M. Inhibition of endothelial nitric oxide synthase activity by protein kinase C. Hypertension 25: 180-185, 1995.
-
(1995)
Hypertension
, vol.25
, pp. 180-185
-
-
Hirata Ki Kuroda, R.1
Sakoda, T.2
Katayama, M.3
Inoue, N.4
Suematsu, M.5
Kawashima, S.6
Yokoyama, M.7
-
75
-
-
0035107609
-
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
-
Hofmann MA, Lalla E, Lu Y, Gleason MR, Wolf BM, Tanji N, Ferran LJ, Kohl B, Rao V, Kisiel W, Stern DM, Schmidt AM. Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model. J Clin Invest 107: 675-683, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 675-683
-
-
Hofmann, M.A.1
Lalla, E.2
Lu, Y.3
Gleason, M.R.4
Wolf, B.M.5
Tanji, N.6
Ferran, L.J.7
Kohl, B.8
Rao, V.9
Kisiel, W.10
Stern, D.M.11
Schmidt, A.M.12
-
76
-
-
68149137621
-
eNOS Syndrome metabolic, Disease cardiovascular
-
Huang PL. eNOS, metabolic syndrome and cardiovascular disease. Trends Endocrinol Metab 20: 295-302, 2009.
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 295-302
-
-
Huang, P.L.1
-
77
-
-
0030872552
-
L-Arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscle
-
Huk I, Nanobashvili J, Neumayer C, Punz A, Mueller M, Afkhampour K, Mittlboeck M, Losert U, Polterauer P, Roth E, Patton S, Malinski T. L-Arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscle. Circulation 96: 667-675, 1997.
-
(1997)
Circulation
, vol.96
, pp. 667-675
-
-
Huk, I.1
Nanobashvili, J.2
Neumayer, C.3
Punz, A.4
Mueller, M.5
Afkhampour, K.6
Mittlboeck, M.7
Losert, U.8
Polterauer, P.9
Roth, E.10
Patton, S.11
Malinski, T.12
-
78
-
-
55249104753
-
Accuracy of quantitative coronary angiography with computed tomography and its dependency on plaque composition
-
Husmann L, Gaemperli O, Schepis T, Scheffel H, Valenta I, Hoefflinghaus T, Stolzmann P, Desbiolles L, Herzog B, Leschka S, Marincek B, Alkadhi H, Kaufmann P. Accuracy of quantitative coronary angiography with computed tomography and its dependency on plaque composition. International J Cardiovasc Imaging 24: 895-904, 2008.
-
(2008)
International J Cardiovasc Imaging
, vol.24
, pp. 895-904
-
-
Husmann, L.1
Gaemperli, O.2
Schepis, T.3
Scheffel, H.4
Valenta, I.5
Hoefflinghaus, T.6
Stolzmann, P.7
Desbiolles, L.8
Herzog, B.9
Leschka, S.10
Marincek, B.11
Alkadhi, H.12
Kaufmann, P.13
-
79
-
-
0036083567
-
Interaction of 5-methyltetrahydrofolate and tetrahydrobiopterin on endothelial function
-
Hyndman ME, Verma S, Rosenfeld RJ, Anderson TJ, Parsons HG. Interaction of 5-methyltetrahydrofolate and tetrahydrobiopterin on endothelial function. Am J Physiol Heart Circ Physiol 282: H2167-H2172, 2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
-
-
Hyndman, M.E.1
Verma, S.2
Rosenfeld, R.J.3
Anderson, T.J.4
Parsons, H.G.5
-
80
-
-
0032707717
-
Nitric oxide as a signaling molecule in the vascular system: An overview
-
Ignarro LJ, Cirino G, Casini A, Napoli C. Nitric oxide as a signaling molecule in the vascular system: an overview. J Cardiovasc Pharmacol 34: 879-886, 1999.
-
(1999)
J Cardiovasc Pharmacol
, vol.34
, pp. 879-886
-
-
Ignarro, L.J.1
Cirino, G.2
Casini, A.3
Napoli, C.4
-
81
-
-
0346157997
-
Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury
-
Iwakura A, Luedemann C, Shastry S, Hanley A, Kearney M, Aikawa R, Isner JM, Asahara T, Losordo DW. Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury. Circulation 108: 3115-3121, 2003.
-
(2003)
Circulation
, vol.108
, pp. 3115-3121
-
-
Iwakura, A.1
Luedemann, C.2
Shastry, S.3
Hanley, A.4
Kearney, M.5
Aikawa, R.6
Isner, J.M.7
Asahara, T.8
Losordo, D.W.9
-
82
-
-
3042677716
-
C-reactive protein: Risk marker or mediator in atherothrombosis?
-
Jialal I, Devaraj S, Venugopal SK. C-reactive protein: risk marker or mediator in atherothrombosis? Hypertension 44: 6-11, 2004.
-
(2004)
Hypertension
, vol.44
, pp. 6-11
-
-
Jialal, I.1
Devaraj, S.2
Venugopal, S.K.3
-
83
-
-
34347397160
-
Homocysteine induces endothelial dysfunction via inhibition of arginine transport
-
RWC
-
Jin L, Caldwell RB, Li-Masters T, RWC. Homocysteine induces endothelial dysfunction via inhibition of arginine transport. J Physiol Pharmacol 58: 191-206, 2007.
-
(2007)
J Physiol Pharmacol
, vol.58
, pp. 191-206
-
-
Jin, L.1
Caldwell, R.B.2
Li-Masters, T.3
-
84
-
-
79960711345
-
Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice
-
Jo H, Otani H, Jo F, Shimazu T, Okazaki T, Yoshioka K, Fujita M, Kosaki A, Iwasaka T. Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice. Clin Exper Pharmacol Physiol 38: 485-493, 2011.
-
(2011)
Clin Exper Pharmacol Physiol
, vol.38
, pp. 485-493
-
-
Jo, H.1
Otani, H.2
Jo, F.3
Shimazu, T.4
Okazaki, T.5
Yoshioka, K.6
Fujita, M.7
Kosaki, A.8
Iwasaka, T.9
-
85
-
-
0030714681
-
Expression of nitric oxide synthase in skeletal muscle: A novel role for nitric oxide as a modulator of insulin action
-
Kapur S, Bedard S, Marcotte B, Cote CH, Marette A. Expression of nitric oxide synthase in skeletal muscle: a novel role for nitric oxide as a modulator of insulin action. Diabetes 46: 1691-1700, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1691-1700
-
-
Kapur, S.1
Bedard, S.2
Marcotte, B.3
Cote, C.H.4
Marette, A.5
-
86
-
-
0035146185
-
Synthase overexpression inhibits lesion formation in mouse model of vascular remodeling
-
Kawashima S, Yamashita T, Ozaki M, Ohashi Y, Azumi H, Inoue N, Hirata Ki Hayashi Y, Itoh H, Yokoyama M. Endothelial NO synthase overexpression inhibits lesion formation in mouse model of vascular remodeling. Arterioscler Thromb Vasc Biol 21: 201-207, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 201-207
-
-
Kawashima, S.1
Yamashita, T.2
Ozaki, M.3
Ohashi, Y.4
Azumi, H.5
Inoue, N.6
Hirata Ki Hayashi, Y.7
Itoh, H.8
Yokoyama, M.9
Endothelial, N.O.10
-
87
-
-
0035200038
-
Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism
-
Kersten JR, Toller WG, Tessmer JP, Pagel PS, Warltier DC. Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism. Am J Physiol Heart Circ Physiol 281: H2097-H2104, 2001.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.281
-
-
Kersten, J.R.1
Toller, W.G.2
Tessmer, J.P.3
Pagel, P.S.4
Warltier, D.C.5
-
88
-
-
79957629912
-
Role of tetrahydrobiopterin (BH4) in hyperhomocysteinemia-induced endothelial dysfuction: New indication for this orphan-drug (LTE)
-
Kietadisorn R, Kietselaer BL, Schmidt HHHW, Moens AL. Role of tetrahydrobiopterin (BH4) in hyperhomocysteinemia-induced endothelial dysfuction: new indication for this orphan-drug? (LTE) Am J Physiol Endocrinol Metab 300: E1176, 2011.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
-
-
Kietadisorn, R.1
Kietselaer, B.L.2
Schmidt, H.H.H.W.3
Moens, A.L.4
-
89
-
-
0032080913
-
Protection from reoxygenation injury by inhibition of rac1
-
Kim KS, Takeda K, Sethi R, Pracyk JB, Tanaka K, Zhou YF, Yu ZX, Ferrans VJ, Bruder JT, Kovesdi I, Irani K, Goldschmidt- Clermont P, Finkel T. Protection from reoxygenation injury by inhibition of rac1. J Clin Invest 101: 1821-1826, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 1821-1826
-
-
Kim, K.S.1
Takeda, K.2
Sethi, R.3
Pracyk, J.B.4
Tanaka, K.5
Zhou, Y.F.6
Yu, Z.X.7
Ferrans, V.J.8
Bruder, J.T.9
Kovesdi, I.10
Irani, K.11
Goldschmidt-clermont, P.12
Finkel, T.13
-
90
-
-
26244432775
-
A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation
-
Kim YM, Guzik TJ, Zhang YH, Zhang MH, Kattach H, Ratnatunga C, Pillai R, Channon KM, Casadei B. A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation. Cir Res 97: 629-636, 2005.
-
(2005)
Cir Res
, vol.97
, pp. 629-636
-
-
Kim, Y.M.1
Guzik, T.J.2
Zhang, Y.H.3
Zhang, M.H.4
Kattach, H.5
Ratnatunga, C.6
Pillai, R.7
Channon, K.M.8
Casadei, B.9
-
91
-
-
0034926855
-
Endothelial function and coronary artery disease
-
Kinlay S, Libby P, Ganz P. Endothelial function and coronary artery disease. Curr Opin Lipidol 12: 383-389, 2001.
-
(2001)
Curr Opin Lipidol
, vol.12
, pp. 383-389
-
-
Kinlay, S.1
Libby, P.2
Ganz, P.3
-
92
-
-
0032029145
-
Impairment of endothelium-dependent vasorelaxation in experimental atherosclerosis is dependent on gender
-
Kojda G, Husgen B, Hacker A, Perings D, Schnaith EM, Kottenberg E, Noack E. Impairment of endothelium-dependent vasorelaxation in experimental atherosclerosis is dependent on gender. Cardiovasc Res 37: 738-747, 1998.
-
(1998)
Cardiovasc Res
, vol.37
, pp. 738-747
-
-
Kojda, G.1
Husgen, B.2
Hacker, A.3
Perings, D.4
Schnaith, E.M.5
Kottenberg, E.6
Noack, E.7
-
93
-
-
0034016067
-
Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia
-
Kossenjans W, Eis A, Sahay R, Brockman D, Myatt L. Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia. Am J Physiol Heart Circ Physiol 278: H1311-H1319, 2000.
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
-
-
Kossenjans, W.1
Eis, A.2
Sahay, R.3
Brockman, D.4
Myatt, L.5
-
94
-
-
0035954312
-
Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice
-
Kuhlencordt PJ, Chen J, Han F, Astern J, Huang PL. Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice. Circulation 103: 3099-3104, 2001.
-
(2001)
Circulation
, vol.103
, pp. 3099-3104
-
-
Kuhlencordt, P.J.1
Chen, J.2
Han, F.3
Astern, J.4
Huang, P.L.5
-
95
-
-
33745934321
-
Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein
-
Kuhlencordt PJ, Hotten S, Schodel J, Rutzel S, Hu K, Widder J, Marx A, Huang PL, Ertl G. Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein E knockout mice. Arterioscler Thromb Vasc Biol 26: 1539-1544, 2006.
-
(2006)
E Knockout Mice. Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1539-1544
-
-
Kuhlencordt, P.J.1
Hotten, S.2
Schodel, J.3
Rutzel, S.4
Hu, K.5
Widder, J.6
Marx, A.7
Huang, P.L.8
Ertl, G.9
-
96
-
-
3943054801
-
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation
-
Kupatt C, Dessy C, Hinkel R, Raake P, Daneau G, Bouzin C, Boekstegers P, Feron O. Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation. Arterioscler Thromb Vasc Biol 24: 1435-1441, 2004.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1435-1441
-
-
Kupatt, C.1
Dessy, C.2
Hinkel, R.3
Raake, P.4
Daneau, G.5
Bouzin, C.6
Boekstegers, P.7
Feron, O.8
-
97
-
-
0038604446
-
Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols
-
Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols. J Biol Chem 278: 22546-22554, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 22546-22554
-
-
Kuzkaya, N.1
Weissmann, N.2
Harrison, D.G.3
Dikalov, S.4
-
98
-
-
33748302921
-
Impairment of the vascular relaxation and differential expression of caveolin-1 of the aorta of diabetic _db/_db mice
-
Lam TY, Seto SW, Lau YM, Au LS, Kwan YW, Ngai SM, Tsui KW. Impairment of the vascular relaxation and differential expression of caveolin-1 of the aorta of diabetic _db/_db mice. Eur J Pharmacol 546: 134-141, 2006.
-
(2006)
Eur J Pharmacol
, vol.546
, pp. 134-141
-
-
Lam, T.Y.1
Seto, S.W.2
Lau, Y.M.3
Au, L.S.4
Kwan, Y.W.5
Ngai, S.M.6
Tsui, K.W.7
-
99
-
-
0037399439
-
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
-
Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest 111: 1201-1209, 2003.
-
(2003)
J Clin Invest
, vol.111
, pp. 1201-1209
-
-
Landmesser, U.1
Dikalov, S.2
Price, S.R.3
McCann, L.4
Fukai, T.5
Holland, S.M.6
Mitch, W.E.7
Harrison, D.G.8
-
100
-
-
20844431696
-
Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase
-
Landmesser U, Engberding N, Bahlmann FH, Schaefer A, Wiencke A, Heineke A, Spiekermann S, Hilfiker-Kleiner D, Templin C, Kotlarz D, Mueller M, Fuchs M, Hornig B, Haller H, Drexler H. Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase. Circulation 110: 1933-1939, 2004.
-
(2004)
Circulation
, vol.110
, pp. 1933-1939
-
-
Landmesser, U.1
Engberding, N.2
Bahlmann, F.H.3
Schaefer, A.4
Wiencke, A.5
Heineke, A.6
Spiekermann, S.7
Hilfiker-Kleiner, D.8
Templin, C.9
Kotlarz, D.10
Mueller, M.11
Fuchs, M.12
Hornig, B.13
Haller, H.14
Drexler, H.15
-
101
-
-
0033800718
-
Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice (Editorial comment)
-
Laufs U, Gertz K, Huang P, Nickenig G, Bohm M, Dirnagl U, Endres M, Vaughan CJ. Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice (Editorial comment). Stroke 31: 2442-2449, 2000.
-
(2000)
Stroke
, vol.31
, pp. 2442-2449
-
-
Laufs, U.1
Gertz, K.2
Huang, P.3
Nickenig, G.4
Bohm, M.5
Dirnagl, U.6
Endres, M.7
Vaughan, C.J.8
-
102
-
-
0032584177
-
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
-
Laufs U, La Fata V, Plutzky J, Liao JK. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97: 1129-1135, 1998.
-
(1998)
Circulation
, vol.97
, pp. 1129-1135
-
-
Laufs, U.1
la Fata, V.2
Plutzky, J.3
Liao, J.K.4
-
103
-
-
84855203002
-
Methods for evaluating endothelial function: A position statement from the European Society of Cardiology Working Group on Peripheral Circulation
-
Lekakis J, Abraham P, Balbarini A, Blann A, Boulanger CM, Cockcroft J, Cosentino F, Deanfield J, Gallino A, Ikonomidis I, Kremastinos D, Landmesser U, Protogerou A, Stefanadis C, Tousoulis D, Vassalli G, Vink H, Werner N, Wilkinson I, Vlachopoulos C. Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation. Eur J Cardiovasc Prev Rehab 2011.
-
(2011)
Eur J Cardiovasc Prev Rehab
-
-
Lekakis, J.1
Abraham, P.2
Balbarini, A.3
Blann, A.4
Boulanger, C.M.5
Cockcroft, J.6
Cosentino, F.7
Deanfield, J.8
Gallino, A.9
Ikonomidis, I.10
Kremastinos, D.11
Landmesser, U.12
Protogerou, A.13
Stefanadis, C.14
Tousoulis, D.15
Vassalli, G.16
Vink, H.17
Werner, N.18
Wilkinson, I.19
Vlachopoulos, C.20
more..
-
104
-
-
79955061886
-
Mthfr deficiency induces endothelial progenitor cell senescence via uncoupling of eNOS and downregulation of SIRT1
-
Lemarie CA, Shbat L, Marchesi C, Angulo OJ, Deschenes ME, Blostein MD, Paradis P, Schiffrin EL. Mthfr deficiency induces endothelial progenitor cell senescence via uncoupling of eNOS and downregulation of SIRT1. Am J Physiol Heart Circ Physiol 300: H745-H753, 2011.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
-
-
Lemarie, C.A.1
Shbat, L.2
Marchesi, C.3
Angulo, O.J.4
Deschenes, M.E.5
Blostein, M.D.6
Paradis, P.7
Schiffrin, E.L.8
-
105
-
-
78650391731
-
Impairment of both nitric oxidemediated and EDHF-type relaxation in small mesenteric arteries from rats with streptozotocin-induced diabetes
-
Leo CH, Hart JL, Woodman OL. Impairment of both nitric oxidemediated and EDHF-type relaxation in small mesenteric arteries from rats with streptozotocin-induced diabetes. Br J Pharmacol 162: 365-377, 2010.
-
(2010)
Br J Pharmacol
, vol.162
, pp. 365-377
-
-
Leo, C.H.1
Hart, J.L.2
Woodman, O.L.3
-
106
-
-
33845226686
-
Increased salt-sensitivity in endothelial nitric oxide synthase-knockout mice
-
Leonard AM, Chafe LL, Montani JP, Van Vliet BN. Increased salt-sensitivity in endothelial nitric oxide synthase-knockout mice. Am J Hypertens 19: 1264-1269, 2006.
-
(2006)
Am J Hypertens
, vol.19
, pp. 1264-1269
-
-
Leonard, A.M.1
Chafe, L.L.2
Montani, J.P.3
van Vliet, B.N.4
-
107
-
-
18544392083
-
Activation of protein kinase Cα and/or ∈ enhances transcription of the human endothelial nitric oxide synthase gene
-
Li H, Oehrlein SA, Wallerath T, Ihrig-Biedert I, Wohlfart P, Ulshofer T, Jessen T, Herget T, Forstermann U, Kleinert H. Activation of protein kinase Cα and/or ∈ enhances transcription of the human endothelial nitric oxide synthase gene. Mol Pharmacol 53: 630-637, 1998.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 630-637
-
-
Li, H.1
Oehrlein, S.A.2
Wallerath, T.3
Ihrig-Biedert, I.4
Wohlfart, P.5
Ulshofer, T.6
Jessen, T.7
Herget, T.8
Forstermann, U.9
Kleinert, H.10
-
108
-
-
79959746256
-
Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow
-
Li L, Chen W, Rezvan A, Jo H, Harrison DG. Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow. Arterioscler Thromb Vasc Biol 31: 1547-1554, 2011.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1547-1554
-
-
Li, L.1
Chen, W.2
Rezvan, A.3
Jo, H.4
Harrison, D.G.5
-
109
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature 420: 868-874, 2002.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
110
-
-
0037143637
-
Impaired nitric oxide synthase pathway in diabetes mellitus: Role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase
-
Lin KY, Ito A, Asagami T, Tsao PS, Adimoolam S, Kimoto M, Tsuji H, Reaven GM, Cooke JP. Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 106: 987-992, 2002.
-
(2002)
Circulation
, vol.106
, pp. 987-992
-
-
Lin, K.Y.1
Ito, A.2
Asagami, T.3
Tsao, P.S.4
Adimoolam, S.5
Kimoto, M.6
Tsuji, H.7
Reaven, G.M.8
Cooke, J.P.9
-
111
-
-
33645753544
-
HOPE-2 Investigators. Homocysteine lowering with folic acid and B vitamins in vascular disease
-
Lonn E, Yusuf S, Arnold MJ, Sheridan P, Pogue J, Micks M, McQueen MJ, Probstfield J, Fodor G, Held; GJ C Jr; HOPE-2 Investigators. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 354: 1567-1577, 2006.
-
(2006)
N Engl J Med
, vol.354
, pp. 1567-1577
-
-
Lonn, E.1
Yusuf, S.2
Arnold, M.J.3
Sheridan, P.4
Pogue, J.5
Micks, M.6
McQueen, M.J.7
Probstfield, J.8
Fodor, G.9
Held Jr, C.G.J.10
-
112
-
-
9144271032
-
Endothelial progenitor cell dysfunction
-
Loomans CJM, de Koning EJP, Staal FJT, Rookmaaker MB, Verseyden C, de Boer HC, Verhaar MC, Braam B, Rabelink TJ, van Zonneveld AJ. Endothelial progenitor cell dysfunction. Diabetes 53: 195-199, 2004.
-
(2004)
Diabetes
, vol.53
, pp. 195-199
-
-
Loomans, C.J.M.1
de Koning, E.J.P.2
Staal, F.J.T.3
Rookmaaker, M.B.4
Verseyden, C.5
de Boer, H.C.6
Verhaar, M.C.7
Braam, B.8
Rabelink, T.J.9
van Zonneveld, A.J.10
-
113
-
-
33645777279
-
Homocysteine trials- clear outcomes for complex reasons
-
Loscalzo J. Homocysteine trials- clear outcomes for complex reasons. N Engl J Med 354: 1629-1632, 2006.
-
(2006)
N Engl J Med
, vol.354
, pp. 1629-1632
-
-
Loscalzo, J.1
-
114
-
-
0034624994
-
What we know and don't know about L-arginine and NO
-
Loscalzo J. What we know and don't know about L-arginine and NO. Circulation 101: 2126-2129, 2000.
-
(2000)
Circulation
, vol.101
, pp. 2126-2129
-
-
Loscalzo, J.1
-
115
-
-
11144311234
-
Time-dependent inhibition and tetrahydrobiopterin depletion of endothelial nitric-oxide synthase caused by cigarettes
-
Lowe ER, Everett AC, Lee AJ, Lau M, Dunbar AY, Berka V, Tsai Al, Osawa Y. Time-dependent inhibition and tetrahydrobiopterin depletion of endothelial nitric-oxide synthase caused by cigarettes. Drug Metab Dispos 33: 131-138, 2005.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 131-138
-
-
Lowe, E.R.1
Everett, A.C.2
Lee, A.J.3
Lau, M.4
Dunbar, A.Y.5
Berka, V.6
Tsai, A.L.7
Osawa, Y.8
-
116
-
-
0034089318
-
Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits
-
Lund DD, Faraci FM, Miller FJ Jr, Heistad DD. Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits. Circulation 101: 1027-1033, 2000.
-
(2000)
Circulation
, vol.101
, pp. 1027-1033
-
-
Lund, D.D.1
Faraci, F.M.2
Miller Jr., F.J.3
Heistad, D.D.4
-
117
-
-
0031265794
-
Biology of the endothelium
-
Lüscher T, Barton M. Biology of the endothelium. Clin Cardiol 20, Suppl II: II-3-II-10, 1997.
-
(1997)
Clin Cardiol
, vol.20
, Issue.SUPPL. II
-
-
Lüscher, T.1
Barton, M.2
-
118
-
-
33744807726
-
Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase
-
Ma FX, Zhou B, Chen Z, Ren Q, Lu SH, Sawamura T, Han ZC. Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase. J Lipid Res 47: 1227-1237, 2006.
-
(2006)
J Lipid Res
, vol.47
, pp. 1227-1237
-
-
Ma, F.X.1
Zhou, B.2
Chen, Z.3
Ren, Q.4
Lu, S.H.5
Sawamura, T.6
Han, Z.C.7
-
119
-
-
0042196814
-
3-Hydroxy- 3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: Balance between transcriptional and posttranscriptional regulation
-
Martinez-Gonzalez J, Raposo B, Rodriguez C, Badimon L. 3-Hydroxy- 3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation. Arterioscler Thromb Vasc Biol 21: 804-809, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 804-809
-
-
Martinez-Gonzalez, J.1
Raposo, B.2
Rodriguez, C.3
Badimon, L.4
-
120
-
-
35549008884
-
SIRT1 promotes endothelium- dependent vascular relaxation by activating endothelial nitric oxide synthase
-
Mattagajasingh I, Kim CS, Naqvi A, Yamamori T, Hoffman TA, Jung SB, DeRicco J, Kasuno K, Irani K. SIRT1 promotes endothelium- dependent vascular relaxation by activating endothelial nitric oxide synthase. Proc Natl Acad Sci USA 104: 14855-14860, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14855-14860
-
-
Mattagajasingh, I.1
Kim, C.S.2
Naqvi, A.3
Yamamori, T.4
Hoffman, T.A.5
Jung, S.B.6
Dericco, J.7
Kasuno, K.8
Irani, K.9
-
121
-
-
0031939771
-
Inducible nitric oxide synthase and blood pressure
-
Mattson DL, Maeda CY, Bachman TD, Cowley AW Jr. Inducible nitric oxide synthase and blood pressure. Hypertension 31: 15-20, 1998.
-
(1998)
Hypertension
, vol.31
, pp. 15-20
-
-
Mattson, D.L.1
Maeda, C.Y.2
Bachman, T.D.3
Cowley Jr., A.W.4
-
122
-
-
33846362954
-
Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
-
Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 292: C82-C97, 2007.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Mehta, P.K.1
Griendling, K.K.2
-
123
-
-
34548151294
-
Circulating endothelial progenitor cells and clinical outcome in patients with congestive heart failure
-
Michowitz Y, Goldstein E, Wexler D, Sheps D, Keren G, George J. Circulating endothelial progenitor cells and clinical outcome in patients with congestive heart failure. Heart 93: 1046-1050, 2007.
-
(2007)
Heart
, vol.93
, pp. 1046-1050
-
-
Michowitz, Y.1
Goldstein, E.2
Wexler, D.3
Sheps, D.4
Keren, G.5
George, J.6
-
124
-
-
0033527413
-
Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
-
Milstien S, Katusic Z. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 263: 681-684, 1999.
-
(1999)
Biochem Biophys Res Commun
, vol.263
, pp. 681-684
-
-
Milstien, S.1
Katusic, Z.2
-
125
-
-
0031456801
-
Plasma levels of nitrite/nitrate and platelet cGMP levels are decreased in patients with atrial fibrillation
-
Minamino T, Kitakaze M, Sato H, Asanuma H, Funaya H, Koretsune Y, Hori M. Plasma levels of nitrite/nitrate and platelet cGMP levels are decreased in patients with atrial fibrillation. Arterioscler Thromb Vasc Biol 17: 3191-3195, 1997.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 3191-3195
-
-
Minamino, T.1
Kitakaze, M.2
Sato, H.3
Asanuma, H.4
Funaya, H.5
Koretsune, Y.6
Hori, M.7
-
126
-
-
32444439891
-
Fc_RIIB mediates C-reactive protein inhibition of endothelial NO synthase
-
Mineo C, Gormley AK, Yuhanna IS, Osborne-Lawrence S, Gibson LL, Hahner L, Shohet RV, Black S, Salmon JE, Samols D, Karp DR, Thomas GD, Shaul PW. Fc_RIIB mediates C-reactive protein inhibition of endothelial NO synthase. Circ Res 97: 1124-1131, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 1124-1131
-
-
Mineo, C.1
Gormley, A.K.2
Yuhanna, I.S.3
Osborne-Lawrence, S.4
Gibson, L.L.5
Hahner, L.6
Shohet, R.V.7
Black, S.8
Salmon, J.E.9
Samols, D.10
Karp, D.R.11
Thomas, G.D.12
Shaul, P.W.13
-
127
-
-
33750728400
-
High- but not low-dose folic acid improves endothelial function in coronary artery disease
-
Moat SJ, Madhavan A, Taylor SY, Payne N, Allen RH, Stabler SP, Goodfellow J, McDowell IFW, Lewis MJ, Lang D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 36: 850-859, 2006.
-
(2006)
Eur J Clin Invest
, vol.36
, pp. 850-859
-
-
Moat, S.J.1
Madhavan, A.2
Taylor, S.Y.3
Payne, N.4
Allen, R.H.5
Stabler, S.P.6
Goodfellow, J.7
McDowell, I.F.W.8
Lewis, M.J.9
Lang, D.10
-
128
-
-
41949135887
-
High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury
-
Moens AL, Champion HC, Claeys MJ, Tavazzi B, Kaminski PM, Wolin MS, Borgonjon DJ, Van Nassauw L, Haile A, Zviman M, Bedja D, Wuyts FL, Elsaesser RS, Cos P, Gabrielson KL, Lazzarino G, Paolocci N, Timmermans JP, Vrints CJ, Kass DA. High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury. Circulation 117: 1810-1819, 2008.
-
(2008)
Circulation
, vol.117
, pp. 1810-1819
-
-
Moens, A.L.1
Champion, H.C.2
Claeys, M.J.3
Tavazzi, B.4
Kaminski, P.M.5
Wolin, M.S.6
Borgonjon, D.J.7
van Nassauw, L.8
Haile, A.9
Zviman, M.10
Bedja, D.11
Wuyts, F.L.12
Elsaesser, R.S.13
Cos, P.14
Gabrielson, K.L.15
Lazzarino, G.16
Paolocci, N.17
Timmermans, J.P.18
Vrints, C.J.19
Kass, D.A.20
more..
-
129
-
-
33846816727
-
Effect of folic acid on endothelial function following acute myocardial infarction
-
Moens AL, Claeys MJ, Wuyts FL, Goovaerts I, Van Hertbruggen E, Wendelen LC, Van Hoof VO, Vrints CJ. Effect of folic acid on endothelial function following acute myocardial infarction. Am J Cardiol 99: 476-481, 2007.
-
(2007)
Am J Cardiol
, vol.99
, pp. 476-481
-
-
Moens, A.L.1
Claeys, M.J.2
Wuyts, F.L.3
Goovaerts, I.4
van Hertbruggen, E.5
Wendelen, L.C.6
van Hoof, V.O.7
Vrints, C.J.8
-
130
-
-
21844470252
-
Flow-mediated vasodilation: A diagnostic instrument, or an experimental tool?
-
Moens AL, Goovaerts I, Claeys MJ, JVC. Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool? Chest 127: 2254-2263, 2005.
-
(2005)
Chest
, vol.127
, pp. 2254-2263
-
-
Moens, A.L.1
Goovaerts, I.2
Claeys, M.J.3
-
131
-
-
33750200993
-
Tetrahydrobiopterin and cardiovascular disease
-
Moens AL, Kass DA. Tetrahydrobiopterin and cardiovascular disease. Arterioscler Thromb Vasc Biol 26: 2439-2444, 2006.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 2439-2444
-
-
Moens, A.L.1
Kass, D.A.2
-
132
-
-
80052807512
-
Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure
-
Moens AL, Ketner EA, Takimoto E, Schmidt TS, O'Neill CA, Wolin MS, Alp NJ, Channon KM, Kass DA. Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure. J Mol Cell Cardiol 51: 564-569, 2011.
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 564-569
-
-
Moens, A.L.1
Ketner, E.A.2
Takimoto, E.3
Schmidt, T.S.4
O'Neill, C.A.5
Wolin, M.S.6
Alp, N.J.7
Channon, K.M.8
Kass, D.A.9
-
133
-
-
79960803194
-
Targeting endothelial and myocardial dysfunction with tetrahydrobiopterin
-
Moens AL, Kietadisorn R, Lin JY, Kass D. Targeting endothelial and myocardial dysfunction with tetrahydrobiopterin. J Mol Cell Cardiol 51: 559-563, 2011.
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 559-563
-
-
Moens, A.L.1
Kietadisorn, R.2
Lin, J.Y.3
Kass, D.4
-
134
-
-
47649122637
-
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: Efficacy of recoupling nitric oxide synthase as a therapeutic strategy
-
Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, Paolocci N, Champion HC, Kass DA. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation 117: 2626-2636, 2008.
-
(2008)
Circulation
, vol.117
, pp. 2626-2636
-
-
Moens, A.L.1
Takimoto, E.2
Tocchetti, C.G.3
Chakir, K.4
Bedja, D.5
Cormaci, G.6
Ketner, E.A.7
Majmudar, M.8
Gabrielson, K.9
Halushka, M.K.10
Mitchell, J.B.11
Biswal, S.12
Channon, K.M.13
Wolin, M.S.14
Alp, N.J.15
Paolocci, N.16
Champion, H.C.17
Kass, D.A.18
-
135
-
-
44949141630
-
Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease
-
Moens AL, Vrints CJ, Claeys MJ, Timmermans JP, Champion HC, Kass DA. Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease. Am J Physiol Heart Circ Physiol 294: H1971-H1977, 2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Moens, A.L.1
Vrints, C.J.2
Claeys, M.J.3
Timmermans, J.P.4
Champion, H.C.5
Kass, D.A.6
-
136
-
-
0037040947
-
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling
-
Mollnau H, Wendt M, Szocs K, Lassegue B, Schulz E, Oelze M, Li H, Bodenschatz M, August M, Kleschyov AL, Tsilimingas N, Walter U, Forstermann U, Meinertz T, Griendling K, Munzel T. Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ Res 90: e58-65, 2002.
-
(2002)
Circ Res
, vol.90
-
-
Mollnau, H.1
Wendt, M.2
Szocs, K.3
Lassegue, B.4
Schulz, E.5
Oelze, M.6
Li, H.7
Bodenschatz, M.8
August, M.9
Kleschyov, A.L.10
Tsilimingas, N.11
Walter, U.12
Forstermann, U.13
Meinertz, T.14
Griendling, K.15
Munzel, T.16
-
137
-
-
0036513249
-
Does nitric oxide modulate mitochondrial energy generation and apoptosis?
-
Moncada S, Erusalimsky JD. Does nitric oxide modulate mitochondrial energy generation and apoptosis? Nat Rev Mol Cell Biol 3: 214-220, 2002.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 214-220
-
-
Moncada, S.1
Erusalimsky, J.D.2
-
138
-
-
0035839532
-
Insulin-stimulated activation of eNOS is independent of Ca2_ but requires phosphorylation by Akt at Ser1179
-
Montagnani M, Chen H, Barr VA, Quon MJ. Insulin-stimulated activation of eNOS is independent of Ca2_ but requires phosphorylation by Akt at Ser1179. J Biol Chem 276: 30392-30398, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 30392-30398
-
-
Montagnani, M.1
Chen, H.2
Barr, V.A.3
Quon, M.J.4
-
139
-
-
67449152446
-
Phosphoinositide 3-kinase signalling in the vascular system
-
Morello F, Perino A, Hirsch E. Phosphoinositide 3-kinase signalling in the vascular system. Cardiovasc Res 82: 261-271, 2009.
-
(2009)
Cardiovasc Res
, vol.82
, pp. 261-271
-
-
Morello, F.1
Perino, A.2
Hirsch, E.3
-
140
-
-
79958802528
-
Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failureinduced alterations in atrial electrophysiology
-
Nishijima Y, Sridhar A, Bonilla I, Velayutham M, Khan M, Terentyeva R, Li C, Kuppusamy P, Elton TS, Terentyev D. Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failureinduced alterations in atrial electrophysiology. Cardiovasc Res 91: 71, 2011.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 71
-
-
Nishijima, Y.1
Sridhar, A.2
Bonilla, I.3
Velayutham, M.4
Khan, M.5
Terentyeva, R.6
Li, C.7
Kuppusamy, P.8
Elton, T.S.9
Terentyev, D.10
-
141
-
-
0027319970
-
Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells
-
Nishinaga M, Ozawa T, Shimada K. Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest 92: 1381-1386, 1993.
-
(1993)
J Clin Invest
, vol.92
, pp. 1381-1386
-
-
Nishinaga, M.1
Ozawa, T.2
Shimada, K.3
-
142
-
-
0028916513
-
Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions
-
Noris M, Morigi M, Donadelli R, Aiello S, Foppolo M, Todeschini M, Orisio S, Remuzzi G, Remuzzi A. Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions. Circ Res 76: 536, 1995.
-
(1995)
Circ Res
, vol.76
, pp. 536
-
-
Noris, M.1
Morigi, M.2
Donadelli, R.3
Aiello, S.4
Foppolo, M.5
Todeschini, M.6
Orisio, S.7
Remuzzi, G.8
Remuzzi, A.9
-
143
-
-
33847073821
-
Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice
-
Oak JH, Cai H. Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice. Diabetes 56: 118-126, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 118-126
-
-
Oak, J.H.1
Cai, H.2
-
144
-
-
35349011597
-
Sirt1 modulates premature senescence-like phenotype in human endothelial cells
-
Ota H, Akishita M, Eto M, Iijima K, Kaneki M, Ouchi Y. Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J Mol Cell Cardiol 43: 571-579, 2007.
-
(2007)
J Mol Cell Cardiol
, vol.43
, pp. 571-579
-
-
Ota, H.1
Akishita, M.2
Eto, M.3
Iijima, K.4
Kaneki, M.5
Ouchi, Y.6
-
145
-
-
0029037532
-
Attenuation of acetylcholine-induced vasoconstriction by -arginine is related to the progression of atherosclerosis
-
Otsuji S, Nakajima O, Waku S, Kojima S, Hosokawa H, Kinoshita I, Okubo T, Tamoto S, Takada K, Tadashi I, Osawa N. Attenuation of acetylcholine-induced vasoconstriction by -arginine is related to the progression of atherosclerosis. Am Heart J 129: 1094-1100, 1995.
-
(1995)
Am Heart J
, vol.129
, pp. 1094-1100
-
-
Otsuji, S.1
Nakajima, O.2
Waku, S.3
Kojima, S.4
Hosokawa, H.5
Kinoshita, I.6
Okubo, T.7
Tamoto, S.8
Takada, K.9
Tadashi, I.10
Osawa, N.11
-
146
-
-
0036330231
-
Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice
-
Ozaki M, Kawashima S, Yamashita T, Hirase T, Namiki M, Inoue N, Hirata Ki Yasui H, Sakurai H, Yoshida Y, Masada M, Yokoyama M. Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice. J Clin Invest 110: 331-340, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 331-340
-
-
Ozaki, M.1
Kawashima, S.2
Yamashita, T.3
Hirase, T.4
Namiki, M.5
Inoue, N.6
Hirata Ki Yasui, H.7
Sakurai, H.8
Yoshida, Y.9
Masada, M.10
Yokoyama, M.11
-
147
-
-
0035092464
-
Reduced hypoxic pulmonary vascular remodeling by nitric oxide from the endothelium
-
Ozaki M, Kawashima S, Yamashita T, Ohashi Y, Rikitake Y, Inoue N, Hirata KI, Hayashi Y, Itoh H, Yokoyama M. Reduced hypoxic pulmonary vascular remodeling by nitric oxide from the endothelium. Hypertension 37: 322-327, 2001.
-
(2001)
Hypertension
, vol.37
, pp. 322-327
-
-
Ozaki, M.1
Kawashima, S.2
Yamashita, T.3
Ohashi, Y.4
Rikitake, Y.5
Inoue, N.6
Hirata, K.I.7
Hayashi, Y.8
Itoh, H.9
Yokoyama, M.10
-
148
-
-
0242409173
-
Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice
-
Pannirselvam M, Simon V, Verma S, Anderson T, Triggle CR. Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice. Br J Pharmacol 140: 701-706, 2003.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 701-706
-
-
Pannirselvam, M.1
Simon, V.2
Verma, S.3
Anderson, T.4
Triggle, C.R.5
-
149
-
-
1042301971
-
C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice
-
Paul A, Ko KWS, Li L, Yechoor V, McCrory MA, Szalai AJ, Chan L. C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Circulation 109: 647-655, 2004.
-
(2004)
Circulation
, vol.109
, pp. 647-655
-
-
Paul, A.1
Ko, K.W.S.2
Li, L.3
Yechoor, V.4
McCrory, M.A.5
Szalai, A.J.6
Chan, L.7
-
150
-
-
0022590909
-
Crucial role of endothelium in the vasodilator response to increased flow in vivo
-
Pohl U, Holtz J, Busse R, Bassenge E. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 8: 37-44, 1986.
-
(1986)
Hypertension
, vol.8
, pp. 37-44
-
-
Pohl, U.1
Holtz, J.2
Busse, R.3
Bassenge, E.4
-
151
-
-
44049104413
-
Tetrahydrobiopterin: A novel antihypertensive therapy
-
Porkert M, Sher S, Reddy U, Cheema F, Niessner C, Kolm P, Jones DP, Hooper C, Taylor WR, Harrison D, Quyyumi AA. Tetrahydrobiopterin: a novel antihypertensive therapy. J Hum Hypertens 22: 401-407, 2008.
-
(2008)
J Hum Hypertens
, vol.22
, pp. 401-407
-
-
Porkert, M.1
Sher, S.2
Reddy, U.3
Cheema, F.4
Niessner, C.5
Kolm, P.6
Jones, D.P.7
Hooper, C.8
Taylor, W.R.9
Harrison, D.10
Quyyumi, A.A.11
-
152
-
-
84857391094
-
The role of tetrahydrobiopterin and dihydrobiopterin in ischemia/reperfusion injury when given at reperfusion
-
Qian C, Katrina E, Christopher Z, Samuel K, Jane C. The role of tetrahydrobiopterin and dihydrobiopterin in ischemia/reperfusion injury when given at reperfusion. Adv Pharmacol Sci 1-11, 2010.
-
(2010)
Adv Pharmacol Sci
, pp. 1-11
-
-
Qian, C.1
Katrina, E.2
Christopher, Z.3
Samuel, K.4
Jane, C.5
-
153
-
-
80052602720
-
Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: Implications for the antiarrhythmic effect of statins
-
Reilly S, Jayaram R, Nahar K, Antoniades C, Verheule S, Channon K, Alp N, Schotten U, Casadei B. Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins. Circulation 124: 1107-1117, 2011.
-
(2011)
Circulation
, vol.124
, pp. 1107-1117
-
-
Reilly, S.1
Jayaram, R.2
Nahar, K.3
Antoniades, C.4
Verheule, S.5
Channon, K.6
Alp, N.7
Schotten, U.8
Casadei, B.9
-
154
-
-
0036249863
-
Interactions of nitric oxide and peroxynitrite with low-density lipoprotein
-
Rubbo H, Trostchansky A, Botti H, Batthyany C. Interactions of nitric oxide and peroxynitrite with low-density lipoprotein. Biol Chem 383: 547-552, 2002.
-
(2002)
Biol Chem
, vol.383
, pp. 547-552
-
-
Rubbo, H.1
Trostchansky, A.2
Botti, H.3
Batthyany, C.4
-
155
-
-
0032831472
-
Salt-induced hypertension in Dahl salt-resistant and salt-sensitive rats with NOS II inhibition
-
Rudd MA, Trolliet M, Hope S, Scribner AW, Daumerie G, Toolan G, Cloutier T, Loscalzo J. Salt-induced hypertension in Dahl salt-resistant and salt-sensitive rats with NOS II inhibition. Am J Physiol Heart Circ Physiol 277: H732-H739, 1999.
-
(1999)
Am J Physiol Heart Circ Physiol
, vol.277
-
-
Rudd, M.A.1
Trolliet, M.2
Hope, S.3
Scribner, A.W.4
Daumerie, G.5
Toolan, G.6
Cloutier, T.7
Loscalzo, J.8
-
156
-
-
0035834028
-
Induction of NAD(P)H oxidase by oxidized low-density lipoprotein in human endothelial cells: Antioxidative potential of hydroxymethylglutaryl coenzyme A reductase inhibitor therapy
-
Rueckschloss U, Galle J, Holtz J, Zerkowski HR, Morawietz H. Induction of NAD(P)H oxidase by oxidized low-density lipoprotein in human endothelial cells: antioxidative potential of hydroxymethylglutaryl coenzyme A reductase inhibitor therapy. Circulation 104: 1767-1772, 2001.
-
(2001)
Circulation
, vol.104
, pp. 1767-1772
-
-
Rueckschloss, U.1
Galle, J.2
Holtz, J.3
Zerkowski, H.R.4
Morawietz, H.5
-
157
-
-
54049094100
-
Leptin enhances the recruitment of endothelial progenitor cells into neointimal lesions after vascular injury by promoting integrin-mediated adhesion
-
Schroeter MR, Leifheit M, Sudholt P, Heida NM, Dellas C, Rohm I, Alves F, Zientkowska M, Rafail S, Puls M, Hasenfuss G, Konstantinides S, Schafer K. Leptin enhances the recruitment of endothelial progenitor cells into neointimal lesions after vascular injury by promoting integrin-mediated adhesion. Circ Res 103: 536-544, 2008.
-
(2008)
Circ Res
, vol.103
, pp. 536-544
-
-
Schroeter, M.R.1
Leifheit, M.2
Sudholt, P.3
Heida, N.M.4
Dellas, C.5
Rohm, I.6
Alves, F.7
Zientkowska, M.8
Rafail, S.9
Puls, M.10
Hasenfuss, G.11
Konstantinides, S.12
Schafer, K.13
-
158
-
-
29944434110
-
L-Arginine therapy in acute myocardial infarction
-
Schulman SP, Becker LC, Kass DA, Champion HC, Terrin ML, Forman S, Ernst KV, Kelemen MD, Townsend SN, Capriotti A, Hare JM, Gerstenblith G. L-Arginine therapy in acute myocardial infarction. JAMA 295: 58-64, 2006.
-
(2006)
JAMA
, vol.295
, pp. 58-64
-
-
Schulman, S.P.1
Becker, L.C.2
Kass, D.A.3
Champion, H.C.4
Terrin, M.L.5
Forman, S.6
Ernst, K.V.7
Kelemen, M.D.8
Townsend, S.N.9
Capriotti, A.10
Hare, J.M.11
Gerstenblith, G.12
-
159
-
-
34249703567
-
C-reactive protein downregulates endothelial NO synthase and attenuates reendothelialization in vivo in mice
-
Schwartz R, Osborne-Lawrence S, Hahner L, Gibson LL, Gormley AK, Vongpatanasin W, Zhu W, Word RA, Seetharam D, Black S, Samols D, Mineo C, Shaul PW. C-reactive protein downregulates endothelial NO synthase and attenuates reendothelialization in vivo in mice. Circ Res 100: 1452-1459, 2007.
-
(2007)
Circ Res
, vol.100
, pp. 1452-1459
-
-
Schwartz, R.1
Osborne-Lawrence, S.2
Hahner, L.3
Gibson, L.L.4
Gormley, A.K.5
Vongpatanasin, W.6
Zhu, W.7
Word, R.A.8
Seetharam, D.9
Black, S.10
Samols, D.11
Mineo, C.12
Shaul, P.W.13
-
160
-
-
42149175901
-
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo
-
Seddon MD, Chowienczyk PJ, Brett SE, Casadei B, Shah AM. Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo. Circulation 117: 1991-1996, 2008.
-
(2008)
Circulation
, vol.117
, pp. 1991-1996
-
-
Seddon, M.D.1
Chowienczyk, P.J.2
Brett, S.E.3
Casadei, B.4
Shah, A.M.5
-
161
-
-
0031442394
-
Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids
-
Shah V, Haddad FG, Garcia-Cardena G, Frangos JA, Mennone A, Groszmann RJ, Sessa WC. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids. J Clin Invest 100: 2923-2930, 1997.
-
(1997)
J Clin Invest
, vol.100
, pp. 2923-2930
-
-
Shah, V.1
Haddad, F.G.2
Garcia-Cardena, G.3
Frangos, J.A.4
Mennone, A.5
Groszmann, R.J.6
Sessa, W.C.7
-
162
-
-
0013054309
-
Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance
-
Shankar RR, Wu Y, Shen HQ, Zhu JS, Baron AD. Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance. Diabetes 49: 684-687, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 684-687
-
-
Shankar, R.R.1
Wu, Y.2
Shen, H.Q.3
Zhu, J.S.4
Baron, A.D.5
-
163
-
-
0037163147
-
Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation
-
Shi Y, Baker JE, Zhang C, Tweddell JS, Su J, Pritchard KA Jr. Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation. Circ Res 91: 300, 2002.
-
(2002)
Circ Res
, vol.91
, pp. 300
-
-
Shi, Y.1
Baker, J.E.2
Zhang, C.3
Tweddell, J.S.4
Su, J.5
Pritchard Jr., K.A.6
-
164
-
-
0022885121
-
Biosynthesis of tetrahydrobiopterin
-
Shin-Ichiro T, Hans-Christoph C, Udo R, Walter L, Sandro G. Biosynthesis of tetrahydrobiopterin. Eur J Biochem 161: 295-302, 1986.
-
(1986)
Eur J Biochem
, vol.161
, pp. 295-302
-
-
Shin-Ichiro, T.1
Hans-Christoph, C.2
Udo, R.3
Walter, L.4
Sandro, G.5
-
165
-
-
0033512422
-
Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta
-
Shinozaki K, Kashiwagi A, Nishio Y, Okamura T, Yoshida Y, Masada M, Toda N, Kikkawa R. Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta. Diabetes 48: 2437-2445, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 2437-2445
-
-
Shinozaki, K.1
Kashiwagi, A.2
Nishio, Y.3
Okamura, T.4
Yoshida, Y.5
Masada, M.6
Toda, N.7
Kikkawa, R.8
-
166
-
-
76349120581
-
Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction
-
Silberman GA, Fan THM, Liu H, Jiao Z, Xiao HD, Lovelock JD, Boulden BM, Widder J, Fredd S, Bernstein KE, Wolska BM, Dikalov S, Harrison DG, Dudley SC Jr. Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction. Circulation 121: 519-528, 2010.
-
(2010)
Circulation
, vol.121
, pp. 519-528
-
-
Silberman, G.A.1
Fan, T.H.M.2
Liu, H.3
Jiao, Z.4
Xiao, H.D.5
Lovelock, J.D.6
Boulden, B.M.7
Widder, J.8
Fredd, S.9
Bernstein, K.E.10
Wolska, B.M.11
Dikalov, S.12
Harrison, D.G.13
Dudley Jr., S.C.14
-
167
-
-
36448943247
-
C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling
-
Singh U, Devaraj S, Vasquez-Vivar J, Jialal I. C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling. J Mol Cell Cardiol 43: 780-791, 2007.
-
(2007)
J Mol Cell Cardiol
, vol.43
, pp. 780-791
-
-
Singh, U.1
Devaraj, S.2
Vasquez-Vivar, J.3
Jialal, I.4
-
168
-
-
77956694480
-
Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS_/_, and iNOS_/_ mice
-
Steed MM, Tyagi N, Sen U, Schuschke DA, Joshua IG, Tyagi SC. Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS_/_, and iNOS_/_ mice. Am J Physiol Lung Cell Mol Physiol 299: L301-L311, 2010.
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.299
-
-
Steed, M.M.1
Tyagi, N.2
Sen, U.3
Schuschke, D.A.4
Joshua, I.G.5
Tyagi, S.C.6
-
169
-
-
0024603895
-
Modifications of low-density lipoprotein that increase its atherogenicity
-
Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum Beyond Cholesterol JL. modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320: 915-924, 1989.
-
(1989)
N Engl J Med
, vol.320
, pp. 915-924
-
-
Steinberg, D.1
Parthasarathy, S.2
Carew, T.E.3
Khoo, J.C.4
Cholesterol, W.B.J.L.5
-
170
-
-
0037197722
-
Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
-
Steinberg D, Witztum JL. Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation 105: 2107-2111, 2002.
-
(2002)
Circulation
, vol.105
, pp. 2107-2111
-
-
Steinberg, D.1
Witztum, J.L.2
-
171
-
-
0037139438
-
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor
-
Stuhlinger MC, Abbasi F, Chu JW, Lamendola C, McLaughlin TL, Cooke JP, Reaven GM, Tsao PS. Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA 87: 1420-1426, 2002.
-
(2002)
JAMA
, vol.87
, pp. 1420-1426
-
-
Stuhlinger, M.C.1
Abbasi, F.2
Chu, J.W.3
Lamendola, C.4
McLaughlin, T.L.5
Cooke, J.P.6
Reaven, G.M.7
Tsao, P.S.8
-
172
-
-
0035923560
-
Homocysteine impairs the nitric oxide synthase pathway: Role of asymmetric dimethylarginine
-
Stuhlinger MC, Tsao PS, Her JH, Kimoto M, Balint RF, Cooke JP. Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation 104: 2569-2575, 2001.
-
(2001)
Circulation
, vol.104
, pp. 2569-2575
-
-
Stuhlinger, M.C.1
Tsao, P.S.2
Her, J.H.3
Kimoto, M.4
Balint, R.F.5
Cooke, J.P.6
-
173
-
-
4544257933
-
Cigarette smoke extract inhibits angiogenesis of pulmonary artery endothelial cells: The role of calpain
-
Su Y, Cao W, Han Z, Block ER. Cigarette smoke extract inhibits angiogenesis of pulmonary artery endothelial cells: the role of calpain. Am J Physiol Lung Cell Mol Physiol 287: L794-L800, 2004.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Su, Y.1
Cao, W.2
Han, Z.3
Block, E.R.4
-
175
-
-
0037216677
-
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: Effects of L-arginine and B vitamins
-
Sydow K, Schwedhelm E, Arakawa N, Bode-Boger SM, Tsikas D, Hornig B, Frolich JC, Boger RH. ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. Cardiovasc Res 57: 244-252, 2003.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 244-252
-
-
Sydow, K.1
Schwedhelm, E.2
Arakawa, N.3
Bode-Boger, S.M.4
Tsikas, D.5
Hornig, B.6
Frolich, J.C.7
Boger, R.H.8
-
176
-
-
8444230851
-
Endothelial dysfunction and reactive oxygen species production in ischemia/reperfusion and nitrate tolerance
-
Szocs K. Endothelial dysfunction and reactive oxygen species production in ischemia/reperfusion and nitrate tolerance. Gen Physiol Biophys 23: 265-296, 2004.
-
(2004)
Gen Physiol Biophys
, vol.23
, pp. 265-296
-
-
Szocs, K.1
-
177
-
-
0035069011
-
Atrial fibrillation impairs endothelial function of forearm vessels in humans
-
Takahashi N, Ishibashi Y, Shimada T, Sakane T, Ohata S, Sugamori T, Ohta Y, Inoue S, Nakamura K, Shimizu H. Atrial fibrillation impairs endothelial function of forearm vessels in humans. J Card Fail 7: 45-54, 2001.
-
(2001)
J Card Fail
, vol.7
, pp. 45-54
-
-
Takahashi, N.1
Ishibashi, Y.2
Shimada, T.3
Sakane, T.4
Ohata, S.5
Sugamori, T.6
Ohta, Y.7
Inoue, S.8
Nakamura, K.9
Shimizu, H.10
-
178
-
-
34250836426
-
A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression
-
Takaya T, Hirata Ki Yamashita T, Shinohara M, Sasaki N, Inoue N, Yada T, Goto M, Fukatsu A, Hayashi T, Alp NJ, Channon KM, Yokoyama M, Kawashima S. A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression. Arterioscler Thromb Vasc Biol 27: 1632-1637, 2007.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1632-1637
-
-
Takaya, T.1
Hirata Ki Yamashita, T.2
Shinohara, M.3
Sasaki, N.4
Inoue, N.5
Yada, T.6
Goto, M.7
Fukatsu, A.8
Hayashi, T.9
Alp, N.J.10
Channon, K.M.11
Yokoyama, M.12
Kawashima, S.13
-
179
-
-
20944445197
-
Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load
-
Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Tavazzi B, Lazzarino G, Paolocci N, Gabrielson KL, Wang Y, Kass DA. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest 115: 1221-1231, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 1221-1231
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Ren, S.4
Rodriguez, E.R.5
Tavazzi, B.6
Lazzarino, G.7
Paolocci, N.8
Gabrielson, K.L.9
Wang, Y.10
Kass, D.A.11
-
181
-
-
41249093674
-
Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification
-
Terashima M, Nguyen PK, Rubin GD, Iribarren C, Courtney BK, Go AS, Fortmann SP, McConnell MV. Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification. JACC Cardiovasc Imaging 1: 167-173, 2008.
-
(2008)
JACC Cardiovasc Imaging
, vol.1
, pp. 167-173
-
-
Terashima, M.1
Nguyen, P.K.2
Rubin, G.D.3
Iribarren, C.4
Courtney, B.K.5
Go, A.S.6
Fortmann, S.P.7
McConnell, M.V.8
-
182
-
-
0034176921
-
Tetrahydrobiopterin biosynthesis, regeneration and functions
-
Thony B, Auerbach G, Blau N. Tetrahydrobiopterin biosynthesis, regeneration and functions. Biochem J 347: 1-16, 2000.
-
(2000)
Biochem J
, vol.347
, pp. 1-16
-
-
Thony, B.1
Auerbach, G.2
Blau, N.3
-
183
-
-
31344475472
-
Spotlight on endothelial progenitor cell inhibitors: Short review
-
Thum T, Bauersachs J. Spotlight on endothelial progenitor cell inhibitors: short review. Vasc Med 10: S59-S64, 2005.
-
(2005)
Vasc Med
, vol.10
-
-
Thum, T.1
Bauersachs, J.2
-
184
-
-
0034739459
-
Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis
-
Tiefenbacher CP, Bleeke T, Vahl C, Amann K, Vogt A, Kubler W. Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis. Circulation 102: 2172-2179, 2000.
-
(2000)
Circulation
, vol.102
, pp. 2172-2179
-
-
Tiefenbacher, C.P.1
Bleeke, T.2
Vahl, C.3
Amann, K.4
Vogt, A.5
Kubler, W.6
-
185
-
-
0029833673
-
Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin
-
Tiefenbacher CP, Chilian WM, Mitchell M, DeFily DV. Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin. Circulation 94: 1423, 1996.
-
(1996)
Circulation
, vol.94
, pp. 1423
-
-
Tiefenbacher, C.P.1
Chilian, W.M.2
Mitchell, M.3
Defily, D.V.4
-
186
-
-
63849086007
-
Cerebral blood flow regulation by nitric oxide: Recent advances
-
Toda N, Ayajiki K, Okamura T. Cerebral blood flow regulation by nitric oxide: recent advances. Pharmacol Rev 61: 62-97, 2009.
-
(2009)
Pharmacol Rev
, vol.61
, pp. 62-97
-
-
Toda, N.1
Ayajiki, K.2
Okamura, T.3
-
187
-
-
70350463869
-
Control of systemic and pulmonary blood pressure by nitric oxide formed through neuronal nitric oxide synthase
-
Toda N, Ayajiki K, Okamura T. Control of systemic and pulmonary blood pressure by nitric oxide formed through neuronal nitric oxide synthase. J Hypertens 27: 1929-1940, 2009.
-
(2009)
J Hypertens
, vol.27
, pp. 1929-1940
-
-
Toda, N.1
Ayajiki, K.2
Okamura, T.3
-
188
-
-
2942558814
-
Homocysteine induces oxidative stress by uncoupling of no synthase activity through reduction of tetrahydrobiopterin
-
Topal G, Brunet A, Millanvoye E, Boucher JL, Rendu F, Devynck MA, David-Dufilho M. Homocysteine induces oxidative stress by uncoupling of no synthase activity through reduction of tetrahydrobiopterin. Free Radic Biol Med 36: 1532-1541, 2004.
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 1532-1541
-
-
Topal, G.1
Brunet, A.2
Millanvoye, E.3
Boucher, J.L.4
Rendu, F.5
Devynck, M.A.6
David-Dufilho, M.7
-
189
-
-
0025542037
-
Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat
-
Tsao PS, Aoki N, Lefer DJ, Johnson G. Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat. Circulation 82: 1402, 1990.
-
(1990)
Circulation
, vol.82
, pp. 1402
-
-
Tsao, P.S.1
Aoki, N.2
Lefer, D.J.3
Johnson, G.4
-
190
-
-
16644369729
-
Neuronal nitric oxide synthase as a novel anti-atherogenic factor
-
Tsutsui M. Neuronal nitric oxide synthase as a novel anti-atherogenic factor. J Atheroscler Thromb 11: 41-48, 2004.
-
(2004)
J Atheroscler Thromb
, vol.11
, pp. 41-48
-
-
Tsutsui, M.1
-
191
-
-
28244492862
-
Mechanisms of homocysteine-induced oxidative stress
-
Tyagi N, Sedoris KC, Steed M, Ovechkin AV, Moshal KS, Tyagi SC. Mechanisms of homocysteine-induced oxidative stress. Am J Physiol Heart Circ Physiol 289: H2649-H2656, 2005.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Tyagi, N.1
Sedoris, K.C.2
Steed, M.3
Ovechkin, A.V.4
Moshal, K.S.5
Tyagi, S.C.6
-
192
-
-
33745395054
-
Erythropoietin-mobilized endothelial progenitors enhance reendothelialization via Akt-endothelial nitric oxide synthase activation and prevent neointimal hyperplasia
-
Urao N, Okigaki M, Yamada H, Aadachi Y, Matsuno K, Matsui A, Matsunaga S, Tateishi K, Nomura T, Takahashi T, Tatsumi T, Matsubara H. Erythropoietin-mobilized endothelial progenitors enhance reendothelialization via Akt-endothelial nitric oxide synthase activation and prevent neointimal hyperplasia. Circ Res 98: 1405-1413, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 1405-1413
-
-
Urao, N.1
Okigaki, M.2
Yamada, H.3
Aadachi, Y.4
Matsuno, K.5
Matsui, A.6
Matsunaga, S.7
Tateishi, K.8
Nomura, T.9
Takahashi, T.10
Tatsumi, T.11
Matsubara, H.12
-
193
-
-
0034758378
-
Endothelial function and nitric oxide: Clinical relevance
-
Vallance P, Chan N. Endothelial function and nitric oxide: clinical relevance. Heart 85: 342, 2001.
-
(2001)
Heart
, vol.85
, pp. 342
-
-
Vallance, P.1
Chan, N.2
-
194
-
-
0036020286
-
Impaired NO-dependent vasodilation in patients with Type II (non-insulin-dependent) diabetes mellitus is restored by acute administration of folate
-
van Etten, de Koning Eelco JP, Verhaar Gaillard, Rabelink
-
van Etten, de Koning Eelco JP, Verhaar Gaillard, Rabelink. Impaired NO-dependent vasodilation in patients with Type II (non-insulin-dependent) diabetes mellitus is restored by acute administration of folate. Diabetologia 45: 1004-1010, 2002.
-
(2002)
Diabetologia
, vol.45
, pp. 1004-1010
-
-
-
195
-
-
70350106731
-
Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: A case-control pilot study
-
van Oostrom O, de Kleijn D, Fledderus J, Pescatori M, Stubbs A, Tuinenburg A, Lim SK, Verhaar M. Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study. Cardiovasc Diabetol 8: 47, 2009.
-
(2009)
Cardiovasc Diabetol
, vol.8
, pp. 47
-
-
van Oostrom, O.1
de Kleijn, D.2
Fledderus, J.3
Pescatori, M.4
Stubbs, A.5
Tuinenburg, A.6
Lim, S.K.7
Verhaar, M.8
-
196
-
-
65449160912
-
Endothelial dysfunction and vascular disease
-
Vanhoutte PM, Shimokawa H, Tang EHC, Feletou M. Endothelial dysfunction and vascular disease. Acta Physiologica 196: 193-222, 2009.
-
(2009)
Acta Physiologica
, vol.196
, pp. 193-222
-
-
Vanhoutte, P.M.1
Shimokawa, H.2
Tang, E.H.C.3
Feletou, M.4
-
197
-
-
17644433975
-
Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
-
Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H, Zeiher AM, Dimmeler S. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89: e1-e7, 2001.
-
(2001)
Circ Res
, vol.89
-
-
Vasa, M.1
Fichtlscherer, S.2
Aicher, A.3
Adler, K.4
Urbich, C.5
Martin, H.6
Zeiher, A.M.7
Dimmeler, S.8
-
198
-
-
0036790604
-
Altered tetrahydrobiopterin metabolism in atherosclerosis: Implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants
-
Vasquez-Vivar J, Duquaine D, Whitsett J, Kalyanaraman B, Rajagopalan S. Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants. Arterioscler Thromb Vasc Biol 22: 1655-1661, 2002.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1655-1661
-
-
Vasquez-Vivar, J.1
Duquaine, D.2
Whitsett, J.3
Kalyanaraman, B.4
Rajagopalan, S.5
-
199
-
-
0037126012
-
Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells
-
Venugopal SK, Devaraj S, Yuhanna I, Shaul P, Jialal I. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells. Circulation 106: 1439-1441, 2002.
-
(2002)
Circulation
, vol.106
, pp. 1439-1441
-
-
Venugopal, S.K.1
Devaraj, S.2
Yuhanna, I.3
Shaul, P.4
Jialal, I.5
-
200
-
-
0034696681
-
Effect of native and oxidized low-density lipoprotein on endothelial nitric oxide and superoxide production: Key role of L-arginine availability
-
Vergnani L, Hatrik S, Ricci F, Passaro A, Manzoli N, Zuliani G, Brovkovych V, Fellin R, Malinski T. Effect of native and oxidized low-density lipoprotein on endothelial nitric oxide and superoxide production: key role of L-arginine availability. Circulation 101: 1261-1266, 2000.
-
(2000)
Circulation
, vol.101
, pp. 1261-1266
-
-
Vergnani, L.1
Hatrik, S.2
Ricci, F.3
Passaro, A.4
Manzoli, N.5
Zuliani, G.6
Brovkovych, V.7
Fellin, R.8
Malinski, T.9
-
201
-
-
0033609454
-
Effects of oral folic acid supplementation on endothelial function in familial hypercholesterolemia: A randomized placebo-controlled trial
-
Verhaar MC, Wever RMF, Kastelein JJP, van Loon D, Milstien S, Koomans HA, Rabelink TJ. Effects of oral folic acid supplementation on endothelial function in familial hypercholesterolemia: a randomized placebo-controlled trial. Circulation 100: 335-338, 1999.
-
(1999)
Circulation
, vol.100
, pp. 335-338
-
-
Verhaar, M.C.1
Wever, R.M.F.2
Kastelein, J.J.P.3
van Loon, D.4
Milstien, S.5
Koomans, H.A.6
Rabelink, T.J.7
-
202
-
-
2442422177
-
C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: Further evidence of a mechanistic link between C-reactive protein and cardiovascular disease
-
Verma S, Kuliszewski MA, Li SH, Szmitko PE, Zucco L, Wang CH, Badiwala MV, Mickle DAG, Weisel RD, Fedak PWM, Stewart DJ, Kutryk MJB. C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease. Circulation 109: 2058-2067, 2004.
-
(2004)
Circulation
, vol.109
, pp. 2058-2067
-
-
Verma, S.1
Kuliszewski, M.A.2
Li, S.H.3
Szmitko, P.E.4
Zucco, L.5
Wang, C.H.6
Badiwala, M.V.7
Mickle, D.A.G.8
Weisel, R.D.9
Fedak, P.W.M.10
Stewart, D.J.11
Kutryk, M.J.B.12
-
203
-
-
0036622464
-
Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: Identifying cellular targetsfor pharmacologic manipulation
-
Verma S, Maitland A, Weisel RD, Fedak PWM, Pomroy NC, Li SH, Mickle DAG, Li RK, Rao V. Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: Identifying cellular targetsfor pharmacologic manipulation. J Thorac Cardiovasc Surg 123: 1074, 2002.
-
(2002)
J Thorac Cardiovasc Surg
, vol.123
, pp. 1074
-
-
Verma, S.1
Maitland, A.2
Weisel, R.D.3
Fedak, P.W.M.4
Pomroy, N.C.5
Li, S.H.6
Mickle, D.A.G.7
Li, R.K.8
Rao, V.9
-
204
-
-
0037143638
-
Self-fulfilling prophecy. C-reactive protein attenuates nitric oxide production and inhibits angiogenesis
-
Verma S, Wang CH, Li SH, Dumont AS, Fedak PWM, Badiwala MV, Dhillon B, Weisel RD, Li RK, Mickle DAG, Stewart DJ. A self-fulfilling prophecy. C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation 106: 913-919, 2002.
-
(2002)
Circulation
, vol.106
, pp. 913-919
-
-
Verma, S.1
Wang, C.H.2
Li, S.H.3
Dumont, A.S.4
Fedak, P.W.M.5
Badiwala, M.V.6
Dhillon, B.7
Weisel, R.D.8
Li, R.K.9
Mickle, D.A.G.10
Stewart, D.J.A.11
-
205
-
-
70449458051
-
Oxidative stress, endothelial dysfunction and atherosclerosis
-
Victor VM, Rocha M, Sola E, Banuls C, Garcia-Malpartida K, Hernandez-Mijares A. Oxidative stress, endothelial dysfunction and atherosclerosis. Curr Pharmaceut Design 15: 2988-3002, 2009.
-
(2009)
Curr Pharmaceut Design
, vol.15
, pp. 2988-3002
-
-
Victor, V.M.1
Rocha, M.2
Sola, E.3
Banuls, C.4
Garcia-Malpartida, K.5
Hernandez-Mijares, A.6
-
206
-
-
0037663840
-
Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin
-
Vincent MA, Barrett EJ, Lindner JR, Clark MG, Rattigan S. Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin. Am J Physiol Endocrinol Metab 285: E123-E129, 2003.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Vincent, M.A.1
Barrett, E.J.2
Lindner, J.R.3
Clark, M.G.4
Rattigan, S.5
-
207
-
-
0037173080
-
Statin therapy accelerates reendothelialization: A novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells
-
Walter DH, Rittig K, Bahlmann FH, Kirchmair R, Silver M, Murayama T, Nishimura H, Losordo DW, Asahara T, Isner JM. Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 105: 3017-3024, 2002.
-
(2002)
Circulation
, vol.105
, pp. 3017-3024
-
-
Walter, D.H.1
Rittig, K.2
Bahlmann, F.H.3
Kirchmair, R.4
Silver, M.5
Murayama, T.6
Nishimura, H.7
Losordo, D.W.8
Asahara, T.9
Isner, J.M.10
-
208
-
-
0030588976
-
Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits
-
Wang BY, Candipan RC, Arjomandi M, Hsiun PT, Tsao PS, Cooke JP. Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits. J Am Coll Cardiol 28: 1573-1579, 1996.
-
(1996)
J Am Coll Cardiol
, vol.28
, pp. 1573-1579
-
-
Wang, B.Y.1
Candipan, R.C.2
Arjomandi, M.3
Hsiun, P.T.4
Tsao, P.S.5
Cooke, J.P.6
-
209
-
-
0345169177
-
Influence of hyperhomocysteinemia on the cellular redox state-impact on homocysteine-induced endothelial dysfunction
-
Weiss N, Heydrick SJ, Postea O, Keller C, Keaney JF, Loscalzo J. Influence of hyperhomocysteinemia on the cellular redox state-impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med 41: 1455-1461, 2003.
-
(2003)
Clin Chem Lab Med
, vol.41
, pp. 1455-1461
-
-
Weiss, N.1
Heydrick, S.J.2
Postea, O.3
Keller, C.4
Keaney, J.F.5
Loscalzo, J.6
-
210
-
-
0031965641
-
Homocysteine-induced nitric oxide production in vascular smooth-muscle cells by NF-kappa B-dependent transcriptional activation of Nos2
-
Welch GN, Upchurch GR Jr, Farivar RSPA, Vu K, Brecher P, Keaney JF Jr, JL. Homocysteine-induced nitric oxide production in vascular smooth-muscle cells by NF-kappa B-dependent transcriptional activation of Nos2. Proc Assoc Am Physicians 110: 22-31, 1998.
-
(1998)
Proc Assoc Am Physicians
, vol.110
, pp. 22-31
-
-
Welch, G.N.1
Upchurch Jr., G.R.2
Farivar, R.S.P.A.3
Vu, K.4
Brecher, P.5
Keaney J.F, J.L.6
-
211
-
-
40949122403
-
Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus
-
Wenzel P, Daiber A, Oelze M, Brandt M, Closs EI, Xu J, Thum T, Bauersachs J, Ertl G, Zou MH, Förstermann U, Müunzel T. Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus. Atherosclerosis 198: 65-76, 2008.
-
(2008)
Atherosclerosis
, vol.198
, pp. 65-76
-
-
Wenzel, P.1
Daiber, A.2
Oelze, M.3
Brandt, M.4
Closs, E.I.5
Xu, J.6
Thum, T.7
Bauersachs, J.8
Ertl, G.9
Zou, M.H.10
Förstermann, U.11
Müunzel, T.12
-
212
-
-
0025943248
-
Lung ischemia-reperfusion injury in awake sheep: Protection with verapamil
-
Wickersham N, Johnson J, Meyrick B, Gilroy R, Loyd J. Lung ischemia-reperfusion injury in awake sheep: protection with verapamil. J Appl Physiol 71: 1554, 1991.
-
(1991)
J Appl Physiol
, vol.71
, pp. 1554
-
-
Wickersham, N.1
Johnson, J.2
Meyrick, B.3
Gilroy, R.4
Loyd, J.5
-
213
-
-
0031444666
-
Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels
-
Wilcox JN, Subramanian RR, Sundell CL, Tracey WR, Pollock JS, Harrison DG, Marsden PA. Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. Arterioscler Thromb Vasc Biol 17: 2479-2488, 1997.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2479-2488
-
-
Wilcox, J.N.1
Subramanian, R.R.2
Sundell, C.L.3
Tracey, W.R.4
Pollock, J.S.5
Harrison, D.G.6
Marsden, P.A.7
-
214
-
-
42449083767
-
Antiatherosclerotic effects of small-molecular-weight compounds enhancing endothelial nitric-oxide synthase (eNOS) expression and preventing eNOS uncoupling
-
Wohlfart P, Xu H, Endlich A, Habermeier A, Closs EI, Hubschle T, Mang C, Strobel H, Suzuki T, Kleinert H, Forstermann U, Ruetten H, Li H. Antiatherosclerotic effects of small-molecular-weight compounds enhancing endothelial nitric-oxide synthase (eNOS) expression and preventing eNOS uncoupling. J Pharmacol Exper Therapeut 325: 370-379, 2008.
-
(2008)
J Pharmacol Exper Therapeut
, vol.325
, pp. 370-379
-
-
Wohlfart, P.1
Xu, H.2
Endlich, A.3
Habermeier, A.4
Closs, E.I.5
Hubschle, T.6
Mang, C.7
Strobel, H.8
Suzuki, T.9
Kleinert, H.10
Forstermann, U.11
Ruetten, H.12
Li, H.13
-
215
-
-
0036799499
-
Cigarette smoke induces rapid changes in gene expression in pulmonary arteries
-
Wright JL, Tai H, Dai J, Churg A. Cigarette smoke induces rapid changes in gene expression in pulmonary arteries. Lab Invest 82: 1391-1398, 2002.
-
(2002)
Lab Invest
, vol.82
, pp. 1391-1398
-
-
Wright, J.L.1
Tai, H.2
Dai, J.3
Churg, A.4
-
216
-
-
0031021827
-
Effect of long-term passive smoking on erectile function and penile nitric oxide synthase in the rat
-
Xie Y, Garban H, Ng C, Rajfer J, Gonzalez-Cadavid NF. Effect of long-term passive smoking on erectile function and penile nitric oxide synthase in the rat. J Urol 157: 1121-1126, 1997.
-
(1997)
J Urol
, vol.157
, pp. 1121-1126
-
-
Xie, Y.1
Garban, H.2
Ng, C.3
Rajfer, J.4
Gonzalez-Cadavid, N.F.5
-
217
-
-
9444220218
-
Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension
-
Xu W, Kaneko FT, Zheng S, Comhair SAA, Janocha AJ, Goggans T, Thunnissen FBJM, Farver C, Hazen SL, Jennings C, Dweik RA, Arroliga AC, Erzurum SC. Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension. FASEB J 18: 1746-1748, 2004.
-
(2004)
FASEB J
, vol.18
, pp. 1746-1748
-
-
Xu, W.1
Kaneko, F.T.2
Zheng, S.3
Comhair, S.A.A.4
Janocha, A.J.5
Goggans, T.6
Thunnissen, F.B.J.M.7
Farver, C.8
Hazen, S.L.9
Jennings, C.10
Dweik, R.A.11
Arroliga, A.C.12
Erzurum, S.C.13
-
218
-
-
77955663336
-
Hyperglycemia induces inducible nitric oxide synthase gene expression and consequent nitrosative stress via c-Jun N-terminal kinase activation
-
Yang P, Cao Y, Li H. Hyperglycemia induces inducible nitric oxide synthase gene expression and consequent nitrosative stress via c-Jun N-terminal kinase activation. Am J Obstet Gynecol 203: 185. e185-185. e111, 2010.
-
(2010)
Am J Obstet Gynecol
, vol.203
, Issue.185
-
-
Yang, P.1
Cao, Y.2
Li, H.3
-
219
-
-
79958789023
-
AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats
-
Yang Q, Xue HM, Wong WT, Tian XY, Huang Y, Tsui SKW, Ng PKS, Wohlfart P, Li H, Xia N, Tobias S, Underwood MJ, He GW. AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats. Br J Pharmacol 163: 1078-1085, 2011.
-
(2011)
Br J Pharmacol
, vol.163
, pp. 1078-1085
-
-
Yang, Q.1
Xue, H.M.2
Wong, W.T.3
Tian, X.Y.4
Huang, Y.5
Tsui, S.K.W.6
Ng, P.K.S.7
Wohlfart, P.8
Li, H.9
Xia, N.10
Tobias, S.11
Underwood, M.J.12
He, G.W.13
-
220
-
-
0027985057
-
Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo
-
Zanzinger J, Czachurski J, Seller H. Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ Res 75: 1073-1077, 1994.
-
(1994)
Circ Res
, vol.75
, pp. 1073-1077
-
-
Zanzinger, J.1
Czachurski, J.2
Seller, H.3
|