Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 7, 2011, Pages 1547-1554

  Li, Li ^a,b   Chen, Wei ^a   Rezvan, Amir ^a   Jo, Hanjoong ^a,c   Harrison, David G ^b,d  

^a Division of Cardiology   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

atherosclerosis; immune system; nitric oxide synthase; reactive oxygen species; superoxide

Indexed keywords

APOLIPOPROTEIN E; CD11B ANTIGEN; CD3 ANTIGEN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; NITRIC OXIDE SYNTHASE; SUPEROXIDE; TETRAHYDROBIOPTERIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL REACTIVITY; CAROTID ARTERY LIGATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME DEFECT; ENZYME UNCOUPLING; IN VIVO STUDY; LEUKOCYTE; LIPID DIET; LOW TEMPERATURE; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN SYNTHESIS; T LYMPHOCYTE; TETRAHYDROBIOPTERIN DEFICIENCY; VASCULITIS; VASODILATATION;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BIOPTERIN; CAROTID ARTERY, COMMON; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; INFLAMMATION; INFLAMMATION MEDIATORS; LIGATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; REGIONAL BLOOD FLOW; SUPEROXIDES; T-LYMPHOCYTES; VASODILATION; VASODILATOR AGENTS;

EID: 79959746256     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.226456     Document Type: Article

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