Microvascular oxygenation, oxidative stress, NO suppression and superoxide dismutase during postischemic reperfusion

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 285, Issue 3 54-3, 2003, Pages

  Bertuglia, S ^a   Giusti, A ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Capillaries; Nitric oxide; Oxygen free radicals; Oxygen tension

Indexed keywords

FREE RADICAL; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; HEART RATE; LEUKOCYTE ADHERENCE; LIPID PEROXIDATION; MALE; MEAN ARTERIAL PRESSURE; MICROVASCULATURE; NONHUMAN; OXIDATIVE STRESS; OXYGEN TENSION; PRIORITY JOURNAL; REPERFUSION INJURY;

EID: 0042860120     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00124.2003     Document Type: Article

References (45)

1. Agullo L, Garcia-Dorado D, Escalona N, Inserte J, Ruiz-Meana M, Barrabes JA, Mirabet M, Pina P, and Soler-Soler J. Hypoxia and acidosis impair cGMP synthesis in moicrovascular coronary endothelial cells. Am J Physiol Heart Circ Physiol 283: H917-H925, 2002.
2. Beckman JS, Beckman TW, Chen J, Marshall PA, and Freeman BA. Apparent hydroxyl radical production by peroxinitrite, implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87: 1620-1624, 1990.
3. Bertuglia S and Colantuoni A. Protective effects of leukopenia and t-PA in ischemia reperfusion injury in hamster cheek pouch microcirculation. Am J Physiol Heart Circ Physiol 278: H755-H761, 2000.
4. Bertuglia S, Colantuoni A, and Intaglietta M. Treatment with L-arginine, L-NMMA, L-NNA in ischemia reperfusion injury in cheek pouch microvasculature. Microvasc Res 50: 162-175, 1995.
5. Bertuglia S and Giusti A. Blockade of P-selectin does not affect reperfusion injury in hamsters subjected to GSH inhibition. Microvasc Res 64: 56-64, 2002.
6. Bertuglia S, Giusti A, Fedele S, and Picano E. Glucose-insulin-potassium treatment in combination with dipyridamole inhibits ischemia-reperfusion-induced damage. Diabetologia 44: 2165-2170, 2001.
7. Bertuglia S, Giusti A, and Pittman RN. Microcirculatory oxygenation and oxygen free radical generation during ischemia and reperfusion. J Vasc Res 39: PIR. 1,32, 2002.
8. 2 measurements in hamster skin fold by recessed P02 microelectrodes and phosphorescence quenching are in agreement. Microcirculation 5: 219-226, 1998.
9. Carey C, Siegfried MR, Ma XL, Weyrich AS, and Lefer AM. Antishock and endothelial protective actions of a NO donor in mesenteric ischemia and reperfusion. Circ Shock 38: 209-216, 1998.
10. Cesarone MR, Belcaro G, and Caratelli M. A simple test to monitor oxidative test. Int Angiol 18: 127-130, 1999.
11. Coste J, Vial JC, Faury G, Deronzier A, Usson Y, Robert-Nicoud M, and Verdetti J. NO synthesis, unlike respiration, influences intracellular oxygen tension. Biochem Biophys Res Commun 290: 97-104, 2002.
12. Damon DN and Duling B. Venular reactivity in the hamster cheek pouch and cremaster muscle. Microvasc Res 31: 379-383, 1986.
13. Droger W. Free radicals in the physiological control of cell function. Physiol Rev 82: 47-95, 2002.
14. Grishman MB, Granger DN, and Lefer DJ. Modulation of leukocyte endothelial interaction by reactive metabolites of oxygen a nitrogen: relevance to ischemic heart disease. Free Radic Biol Med 25: 404-433, 1998.
15. Golub A, Popel AS, Zheng L, and Pittman RN. Analysis of phosphorescence in heterogeneous systems using distributions of quencher concentration. Biophys J 73: 452-465, 1999.
16. Hearse DJ, Maxwell L, Saldanha C, and Gavin JB. The myocardial vasculature during ischemia and reperfusion: a target for injury and protection. J Mol Cardiol 25: 759-800, 1993.
17. Ince C, Ashruf JF, Avontour JA, Wieringa PA, Spaan JA, and Bruining HA. Heterogeneity of the hypoxic state in rat heart is determined at capillary level. Am J Physiol Heart Circ Physiol 264: H294-H301, 1993.
18. Intaglietta M, Johnson PC, and Winslow RM. Microvascular and tissue oxygen distribution. Cardiovasc Res 32: 632-643,1996.
19. Itoh T, Yaegashi K, Kosaka T, Kinoshita T, and Morimoto T. In vivo visualization of oxygen transport in microvascular network. Am J Physiol Heart Circ Physiol 267: H2068-H2078, 1994.
20. Jolly SR, Kane WJ, Bailie MB, Abrams GD, and Lucchesi BR. Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase. Circ Res 3: 277-285, 1984.
21. Jones SP, Hoffmeyer MR, Sharp BR, Ho YS, and Lefer DJ. Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol 284: H277-H282, 2003.
22. Jugdutt BI. Nitric oxide and cardioprotection during ischemia-reperfusion. Heart Fail Rev 7: 391-405, 2002.
23. Kadambi A and Skalak TC. Role of leukocyes and tissue derived oxidants in short term skeletal muscle ischemia reperfusion injury. Am J Physiol Heart Circ Physiol 278: H435-H443, 2000.
24. Kashiwagi S, Kajimura M, Yoshimura Y, and Suematsu M. Nonendothelial source of nitric oxide in arterioles but not in venules: alternative source revealed in vivo by diaminofluorescein microfluorography. Circ Res 13, Suppl 91: e55-e64, 2002.
25. Kenneth L, Giovanelli CJ, and Kaufman S. Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide. J Biol Chem 270: 1721-1728, 1995.
26. Kubes P, Ibbotson G, Russel E, Wallace JL, and Granger DN. Influence of white blood cell in ischemia-reperfusion-induced leukocyte adhesion. Am J Physiol Gastrointest Liver Physiol 259: G300-G305, 1990.
27. Kurose I, Argenbright LW, Wolf R, Lianxi L, and Granger DN. Ischemia-reperfusion-induced microvascular dysfunction: role of oxidants and lipid mediator. Am J Physiol Heart Circ Physiol 272: H2976-H2982, 1997.
28. Lo SK, Janakidevi K, Lai L, and Malik AB. Hydrogen peroxide-induced increase in endothelial adhesiveness is dependent on ICAM-1 activaction. Am J Physiol Lung Cell Mol Physiol 264: L406-L412, 1993.
29. Menger MD, Pelikan S, Steiner D, and Messmer K. Microvascular ischemia-reperfusion injury in striated muscle: significance of reflow paradox. Am J Physiol Heart Circ Physiol 263: H1901-H1906, 1992.
30. Popel AS, Pittman RN, and Ellsworth ML. Rate of oxygen loss from arterioles is an order of magnitude higher than expected. Am J Physiol Heart Circ Physiol 256: H921-H924, 1989.
31. Richard VJ, Murry CE, Jennings RB, and Reimer KA. Therapy to reduce free radicals during early reperfusion does not limit the size of myocardial infarcts caused by 90 min of ischemia in dogs. Circulation 2: 473-480, 1988.
32. Shah S, Allen JA, Wood JG, and Gonzalez NC. Dissociation between skeletal muscle microvascular P02 and hypoxia-induced microvascular inflammation. J Appl Physiol 94: 2323-2329, 2003.
33. Suematsu M, Suzuki K, Ishii H, Kato S, Yanagisawa T, Asako H, Suzuki M, and Tsuchiya M. Early midzonal oxida tive stress preceding cell death in hypoperfused rat liver. Gastroenterology 103: 994-1001, 1992.
34. Suematsu M, Tamatani T, Delano FA, Miyasaka M, Forrest M, Suzuki H, and Schmid-Schonbein GW. Microvascular oxidative stress preceding leukocyte activation elicited by in vivo nitric oxide suppression. Am J Physiol Heart Circ Physiol 266: H2410-H2415, 1994.
35. Swain DP and Pittman RN. Oxygen exchange in the microcirculation of hamster cremaster muscle. Am J Physiol Heart Circ Physiol 256: H247-H255, 1989.
36. Takehara T, Nakahara H, Okada K, Hamazaki K, Yamazato A, Inoue M, Utsumi K. Oxygen concentration regulates NO-dependent relaxation of aortic smooth muscles. Free Radic Res 30: 287-294, 1999.
37. Tomoda H, Morimoto K, and Aoki N. Superoxide dismutase activity as a predictor of myocardial reperfusion and salvage in acute myocardial infarct. Am Heart J 131: 849-856, 1998.
38. 2 measurements by phosphorence decay method. Am J Physiol Heart Circ Physiol 265: H1434-H1438, 1993.
39. Tsao PS and Lefer AM. Time course and mechanism of endothelial dysfunction in isolated ischemic and hypoxic perfused rat hearts. Am J Physiol Heart Circ Physiol 259: H1660-H1666, 1990.
40. Uraizee A, Reimer KA, Murry CE, and Jennings RB. Failure of superoxide dismutase to limit size of myocardial infarction after 40 min of ischemia and 4 days of reperfusion. Circulation 6: 1237-1248, 1987.
41. Vetterlein F, Prange M, Lubrich D, Pedina J, Neckel M, and Schmidt G. Capillary perfusion pattern and microvascular geometry in heterogenous hypoxic areas of hypoperfused rat myocardium. Am J Physiol Heart Circ Physiol 268: H2183-H2194, 1995.
42. Whorton AR, Simonds DB, and Piantadosi CA. Regulation of nitric oxide synthesis by oxygen in vascular endothelial cells. Am J Physiol Lung Cell Mol Physiol 272: L1161-L1166, 1997.
43. Wolin MS. Interactions of oxidants with vascular signaling systems. Arterioscler Thromb Vasc Biol 20: 1430-1442, 2000.
44. Kakita T, Suzuki M, Takeuchi H, Unno M, and Matsuno S. Significance of xanthine oxidase in the production of intracellular oxygen radicals in an in-vitro hypoxia-reoxygenation model. J Hepatobiliary Pancreat Surg 9: 249-255, 2002.
45. Yoshida N, Granger DN, Anderson DC, Rothlein R, Lane C, and Kvietys PR. Anoxia reoxygenation induced neutrophil adherence to cultured endothelial cells. Am J Physiol Heart Circ Physiol 262: H1891-H1895, 1992.