Hyperglycemia induces apoptosis of pancreatic islet endothelial cells via reactive nitrogen species-mediated Jun N-terminal kinase activation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1813, Issue 6, 2011, Pages 1211-1219

  Gong, Lei ^a   Liu, Fu qiang ^a   Wang, Juan ^a   Wang, Xu ping ^a   Hou, Xin guo ^a   Sun, Yu ^a   Qin, Wei dong ^a   Wei, Shu jian ^a   Zhang, Yun ^a   Chen, Li ^a   Zhang, Ming Xiang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Hyperglycemia; JNK; Pancreatic islet endothelial cells; Reactive nitrogen species

Indexed keywords

CASPASE 3; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PEROXYNITRITE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE NITROGEN SPECIES; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; ENZYME ACTIVATION; HYPERGLYCEMIA; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

AMIDINES; ANIMALS; ANTHRACENES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZYLAMINES; BLOTTING, WESTERN; CASPASE 3; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUCOSE; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PEROXYNITROUS ACID; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE NITROGEN SPECIES;

EID: 79955656767     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.03.011     Document Type: Article

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