Human macrophage-induced vascular smooth muscle cell apoptosis requires NO enhancement of Fas/Fas-L interactions

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 10, 2002, Pages 1624-1630

  Boyle, Joseph J ^a,b   Weissberg, Peter L ^a   Bennett, Martin R ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Fas; Macrophages; Nitric oxide; Plaque rupture; Vascular smooth muscle cells

Indexed keywords

FAS ANTIGEN; FAS LIGAND; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; NITROPRUSSIDE SODIUM;

APOPTOSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL CULTURE; CELL INTERACTION; CONTROLLED STUDY; ENANTIOMER; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; VASCULAR SMOOTH MUSCLE;

ANTIGENS, CD95; APOPTOSIS; AUTOCRINE COMMUNICATION; CAROTID ARTERY DISEASES; CELLS, CULTURED; ENZYME INHIBITORS; FAS LIGAND PROTEIN; GOLGI APPARATUS; HUMANS; LIGANDS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITROPRUSSIDE; OMEGA-N-METHYLARGININE; POLYAMINES; PROTEIN TRANSPORT; UP-REGULATION;

EID: 0036791644     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000033517.48444.1A     Document Type: Article

References (38)

1. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999;340:115-126.
2. van der Wal AC, Becker AE, van der Loos CM, Das PK. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation. 1994;89:36-44.
3. Bennett MR. Apoptosis of vascular smooth muscle cells in vascular remodelling and atherosclerotic plaque rupture. Cardiovasc Res. 1999;41:361-368.
4. Bauriedel G, Schmucking I, Hutter R, Luchesi C, Welsch U, Kandolf R, Luderitz B. Increased apoptosis and necrosis of coronary plaques in unstable angina [in German]. Z Kardiol. 1997;86:902-910.
5. Bauriedel G, Hutter R, Welsch U, Bach R, Sievert H, Luderitz B. Role of smooth muscle cell death in advanced coronary primary lesions: implications for plaque instability. Cardiovasc Res. 1999;41:480-488.
6. Newby AC, Libby P, van der Wal AC. Plaque instability: the real challenge for atherosclerosis research in the next decade? Cardiovasc Res. 1999;41:321-322.
7. Boyle JJ, Bowyer DE, Weissberg PL, Bennett MR. Human blood-derived macrophages induce apoptosis in human plaque-derived vascular smooth muscle cells by Fas-ligand/Fas interactions. Arterioscler Thromb Vase Biol. 2001;21:1402-1407.
8. Martin JH, Edwards SW. Interferon-gamma enhances monocyte cytotoxicity via enhanced reactive oxygen intermediate production: absence of an effect on macrophage cytotoxicity is due to failure to enhance reactive nitrogen intermediate production. Immunology. 1994;81:592-597.
9. Martin JH, Edwards SW. Changes in mechanisms of monocyte/macrophage-mediated cytotoxicity during culture: reactive oxygen intermediates are involved in monocyte-mediated cytotoxicity, whereas reactive nitrogen intermediates are employed by macrophages in tumor cell killing. J Immunol. 1993;150:3478-3486.
10. Leone AM, Furst VW, Foxwell NA, Cellek S, Moncada S. Visualisation of nitric oxide generated by activated murine macrophages. Biochem Biophys Res Commun. 1996;221:37-41.
11. Gross SS, Wolin MS. Nitric oxide: pathophysiological mechanisms. Annu Rev Physiol. 1995;57:737-769.
12. Albina JE. On the expression of nitric oxide synthase by human macrophages: why no NO? J Leukoc Biol. 1995;58:643-649.
13. Gross A, Dugas N, Spiesser S, Vouldoukis I, Damais C, Kolb JP, Dugas B, Domand J. Nitric oxide production in human macrophagic cells phagocytizing opsonized zymosan: direct characterization by measurement of the luminol dependent chemiluminescence. Free Radic Res. 1998;28:179-191.
14. Forrester K, Ambs S, Lupold SE, Kapust RB, Spillare EA, Weinberg WC, Felley BE, Wang XW, Geller DA, Tzeng E, Billiar TR, Harris CC. Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. Proc Natl Acad Sci U S A. 1996;93:2442-2447.
15. Bennett M, Macdonald K, Chan SW, Luzio JP, Simari R, Weissberg P. Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. Science. 1998;282:290-293.
16. Bossi G, Griffiths GM. Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells. Nat Med. 1999;5:90-96.
17. Smith RJ, Ignarro LJ. Bioregulation of lysosomal enzyme secretion from human neutrophils: roles of guanosine 3′:5′-monophosphate and calcium in stimulus-secretion coupling. Proc Natl Acad Sci USA. 1975;72:108-112.
18. Geng YJ, Hansson GK. Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages. J Clin Invest. 1992;89:1322-1330.
19. de Fougerolles AR, Chi-Rosso G, Bajardi A, Gotwals P, Green CD, Koteliansky VE. Global expression analysis of extracellular matrixintegrin interactions in monocytes. Immunity. 2000;13:749-758.
20. Bennett MR, Littlewood TD, Schwartz SM. Weissberg PL. Increased sensitivity of human vascular smooth muscle cells from atherosclerotic plaques to p53-mediated apoptosis. Cire Res. 1997;81:591-599.
21. Kolb JP, Paul-Eugene N, Damais C, Yamaoka K, Drapier JC, Dugas B. Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes: involvement of the nitric oxide synthase pathway. J Biol Chem. 1994;269:9811-9816.
22. Lloyd-Jones DM, Bloch KD. The vascular biology of nitric oxide and its role in atherogenesis. Annu Rev Med. 1996;47:365-375.
23. Podrez EA, Febbraio M, Sheibani N, Schmitt D, Silverstein RL, Hajjar DP, Cohen PA, Frazier WA, Hoff HF, Hazen SL. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. J Clin Invest. 2000;105:1095-1108.
24. Weinberg JB, Granger DL, Pisetsky DS, Seldin MF, Misukonis MA, Mason SN, Pippen AM, Ruiz P, Wood ER, Gilkeson GS. The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-Larginine. J Exp Med. 1994;179:651-660.
25. Kim YM, Bombeck CA, Billiar TR. Nitric oxide as a bifunctional regulator of apoptosis. Circ Res. 1999;84:253-256.
26. Moore WM, Webber RK, Jerome GM, Tjoeng FS, Misko TP, Currie MG. L-N6-(1-Iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J Med Chem. 1994;37:3886-3888.
27. Faraci WS, Nagel AA, Verdries KA, Vincent LA, Xu H, Nichols LE, Labasi JM, Salter ED, Pettipher ER. 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo. Br J Pharmacol. 1996;119:1101-1108.
28. Andreesen R, Brugger W, Scheibenbogen C, Kreutz M, Leser HG, Rehm A, Lohr GW. Surface phenotype analysis of human monocyte to macrophage maturation. J Leukoc Biol. 1990;47:490-497.
29. Lippincott-Schwartz J, Yuan L, Tipper C, Amherdt M, Orci L, Klausner RD. Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell. 1991;67:601-616.
30. Chardin P, McCormick F, Brefeldin A: the advantage of being uncompetitive. Cell. 1999;97:153-155.
31. Geng YJ, Henderson LE, Levesque EB, Muszynski M, Libby P. Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine-primed human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1997;17:2200-2208.
32. Beltran B, Mathur A, Duchen MR, Erusalimsky JD, Moncada S. The effect of nitric oxide on cell respiration: a key to understanding its role in cell survival or death. Proc Natl Acad Sci U S A. 2000;97:14602-14607
33. Fukuo K, Hata S, Suhara T, Nakahashi T, Shinto Y, Tsujimoto Y, Morimoto S, Ogihara T. Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle. Hypertension. 1996;27:823-826.
34. Chung HT, Pae HO, Choi BM, Billiar TR, Kim YM. Nitric oxide as a bioregulator of apoptosis. Biochem Biophys Res Commun. 2001;282:1075-1079.
35. Esaki T, Hayashi T, Muto E, Kano H, Kumar TN, Asai Y, Sumi D, Iguchi A. Expression of inducible nitric oxide synthase and Fas/Fas ligand correlates with the incidence of apoptotic cell death in atheromatous plaques of human coronary arteries. Nitric Oxide. 2000;4:561-571.
36. Esaki T, Hayashi T, Asai Y, Kumar TN, Kano H, Muto E, Iguchi A. Expression of inducible nitric oxide synthase in T lymphocytes and macrophages in vessels with advanced atherosclerosis. Heart Vessels. 1997;(suppl 12):89-92.
37. Kockx MM, De Meyer GR, Muhring J, Jacob W, Bult H, Herman AG. Apoptosis and related proteins in different stages of human atherosclerotic plaques. Circulation. 1998;97:2307-2315.
38. Yende S. Treatment of acute coronary syndromes. N Engl J Med. 2002;346:206-208.